Immune Design up 19% [Jun 21,17]
Immunogen up 11% [Jun 21,17]
Cellular Biomedicine up 10% [Jun 21,17]
Myomo down 23% [Jun 21,17]
Syntimmune (New York, NY; no SBIR, founded 2013)’s leaders believe their company has found a way to block the immune system’s attack on the body. And now the biotech has $50 million to advance its lead drug through clinical trials in two rare diseases. ... focusing its research on two autoimmune diseases. The first is pemphigus, a group of rare skin disorders that cause blisters and sores on the skin or mucus membranes. The second is warm autoimmune hemolytic anemia, a disorder in which healthy red blood cells are destroyed by the body’s own antibodies. [Frank Vinluan, xconomy.com, Jun 21, 17]
RE2 Robotics (Pittsburgh, PA; at least $4.5M SBIR) announced that the Company was selected by the Air Force SBIR to develop a drop-in robotic system to rapidly convert a variety of traditionally manned aircraft to robotically piloted, autonomous aircraft. This robotic system, named “Common Aircraft Retrofit for Novel Autonomous Control” (CARNAC), will operate the aircraft similarly to a human pilot and will not require any modifications to the aircraft. [company press release, Jun 21, 17]
Sigilon Therapeutics (Cambridge, MA; no SBIR, founded 2016) biotech, announced it has raised $23.5 million to take its technology to clinical trials. [David Holley, xconomy.com, Jun 21, 17]
Arena Pharma up 12% [Jun 20,17]
Immunogen up 10% [Jun 20,17]
ConforMIS down 10% [Jun 20,17]
Neos Therapeutics (Dallas, TX; no SBIR, IPO 2015) developing, manufacturing and commercializing innovative extended-release (XR) products using its proprietary modified-release drug delivery and orally disintegrating tablet (ODT) technologies, announced that [FDA] approved Cotempla XR-ODT, the first and only methylphenidate extended-release orally disintegrating tablet for the treatment of attention-deficit/hyperactivity disorder (ADHD) in patients 6 to 17 years old. [company press release, Jun 19, 17]
Aziyo Biologics (Richmond, CA and Silver Spring, MD; no SBIR, founded 2015) raised $12 million in a recent funding round, [SEC] filing shows. [Tina Reed, Washington Business Journal, Jun 14, 17] ..... a fully integrated regenerative medicine company, announced it has completed an asset purchase agreement with CorMatrix® Cardiovascular (Roswell, GA; no SBIR), for the purchase of all CorMatrix commercial assets and related intellectual property. [company press release, May 31, 17] .... vision is to impact healthcare through innovation of new solutions realizing the commercial potential of regenerative medicine. KeraLink is one of the world’s leading eye banks with a mission to reverse corneal blindness through transplantation. [company website]
AquaHarmonics (Oregon City, OR; no SBIR) grand-prize winner of the Wave Energy Prize [$5M] — a [federal] Energy Department-funded public competition to increase the energy capture potential of wave energy devices—will build a larger version of its winning device for open-ocean testing. regon-based AquaHarmonics won the Wave Energy Prize competition by demonstrating a five-fold improvement in energy capture per unit structural cost. The company will seek to upscale its device while maintaining low costs. runner-up California Wave Power Technologies (Berkeley, CA; no SBIR) will upscale its WEC technology for open-ocean testing. ... CWPT's device demonstrated more than a three-fold improvement in energy capture per unit structural cost. Through testing, the alifornia-based company will validate and update estimated costs for a full-scale version of its technology. [press release, USDOE, Jun 15, 17] total money to all four winners: $12M
Innovate Biopharmaceuticals (Raleigh, NC; no SBIR) is poised to become a public company through a reverse merger with California-based Monster Digital [Jennifer Henderson, Triangle Business Journal, Jun 20, 17] Innovate’s lead drug candidate, larazotide acetate (INN-202), is the only drug which has successfully met its primary endpoint in an efficacy clinical trial for celiac disease. [Monster press release]
Dova Pharmaceuticals (Durham, NC; no SBIR) set terms of its [IPO] which the developer of drug candidates for diseases treated by specialist physicians expects to raise up to $69.1 million [Tomi Kilgore, MarketWatch, Jun 20, 17]
a Canadian gentleman asked me a simple question: “What do you fear most these days?” ... “I fear we’re seeing the end of ‘truth’ — that we simply can’t agree any more on basic facts. And I fear that we’re becoming Sunnis and Shiites — we call them ‘Democrats’ and ‘Republicans,’ but the sectarianism that has destroyed nation-states in the Middle East is now infecting us.” [Tom Friedman, New York Times, Jun 20, 17]
Myomo up 34% [Jun 19,17]
Seattle Genetics said it is discontinuing a Phase 3 clinical trial after data showed “a higher rate of deaths, including fatal infections” in acute myeloid leukemia (AML) patients receiving its drug than in the study’s other patients. [Seattle Times, Jun 19, 17]
Stratasys (Eden Prairie, MN; no SBIR) added the maker of a new generation, high-speed aircraft to its roster of aerospace customers. Boom Supersonic (Denver, CO; no SBIR) aviation startup, is deploying Stratasys 3-D printing capabilities to build its new supersonic passenger airplane capable of flying nearly three times as fast as any commercial aircraft on the market, according to a news release from both companies. ... Stratasys generated $672 million in 2016 [Nick Williams, Minneapolis / St. Paul Business Journal, Jun 15, 17]
Fallen Angels. Despite hailed by medtech and biotech entrepreneurs as a vital piece of the puzzle in efforts to translate Minnesota’s leadership in medical research into startup businesses. ... The Minnesota High Tech Association asserts $377 million in business investment has been tied to the credits since their inception in 2010. .... an intense lobbying effort from “dozens of companies and organizations.” “the funding for the Angel Tax Credit was removed” [Don Jacobson, Twin Cities Business, Jun 7, 17] Politics of subsidies usually lacks credible accounting for what would have happened without the subsidy. Minnesota legislators may have called the bluff.
[$258 million in research contracts to six companies developing supercomputing technology] comes after a White House budget proposal advocated nixing research and development funding across agencies and especially at the Energy Department. .... proposed eliminating the Energy Department’s R&D unit, the Advanced Research Project Agency-Energy, or ARPA-E, because “the private sector is better positioned to finance disruptive energy technology research and development." [Mohana Ravindranath, nextgov.com, Jun 19, 17] Great trust in private investment in innovation that might undercut present technology investment. Ah well, whatever works to cut taxes (and the many present R&D jobs paying good wages).
Myomo up 61% [Jun 16,17]
Eastern New York Angels is seeking entrepreneurs who are interested in obtaining early stage funding ... with a primary focus for companies located within the 11 county region surrounding Albany known as Tech Valley. recently closed its latest investment in Free Form Fibers (Saratoga Springs, NY; one SBIR)[which] created a new technology to manufacture high-performance fibers (HPF) at a substantially lower cost and environmental impact than competing processes. [Eastern Angels website].
Myomo up 33% [Jun 15,17]
Epizyme up 17% [Jun 15,17]
Advaxiz down 11% [Jun 15,17]
Merck KGaA (Germany) pharmaceutical and life sciences company, launched a digital information center where it will experiment with virtual and augmentsed reality. [Will Anderson, Austin Business Journal , Jun 12, 17]
Athenex up 14% [Jun 14,17] after raising $66M in IPO to devote mostly to a pair of cancer drugs in late-stage clinical development. [company press release]
Omeros up 12% [Jun 14,17]
Epizyme up 11% [Jun 14,17]
Omeros up 15% [Jun 13,17]
GTx (Memphis, TN; $300K SBIR) down 22% [Jun 13,17] after 99% rise on Jun 12 after announced release of preliminary clinical data from its ongoing, open-label, Phase 2 clinical trial of enobosarm 3 mg (GTx-024) in postmenopausal women with stress urinary incontinence (SUI). [company press release, Jun 12, 17]
Reaching for the stars. Princeton Satellite Systems (Plainsboro, NJ; $7M SBIR) was selected for two NASA STTRs on their new topic, T2.01-9960, Advanced Nuclear Propulsion! Our research institution partner is Princeton Plasma Physics Laboratory. Our proposals were featured in NASA’s official press release! Here is a quote: High temperature superconducting coils for a future fusion reaction space engine. These coils are needed for the magnetic field that allows the engine to operate safely. Nuclear fusion reactions are what power our sun and other stars, and an engine based on this technology would revolutionize space flight. [company press release, Jun 6, 17]
every single one of America’s 493 wealthiest counties, almost all of them urban, voted for Hillary Clinton. The remaining 2623 counties, most of them suburban or small-town, went for Donald Trump [Edward Luce, The Retreat of Western Liberalism, Jun 2017] And the Republican Congress is doing its best to serve those rich counties while the richest-ever President dithers about what his mandate means and how to pursue it.
XBIOTECH up 31% [Jun 12,17]
Omeros up 12% [Jun 12,17]
Dynavax Tech up 10% [Jun 12,17]
Enzo Biochem (NYC, NY; $1.5M SBIR) up 13% [Jun 9,17]
XBIOTECH down 66% [Jun 9,17] announced today that an Independent Data Monitoring Committee (IDMC) ... recommended the early termination of the study since the findings were not sufficient to meet efficacy or the threshold forcontinuation, which involved a prospectively defined acceptance boundary for the interim analysis [company press release, Jun 9, 17]
Applied Optoelectronics down 12% [Jun 9,17]
Medical-robotics maker Myomo (Cambridge,MA; one SBIR) completed its [$8M IPO] and is now set to become the first company to list on a major U.S. exchange through a little-used provision of federal law known as Reg A+. .... makes orthotic devices for people with upper-body paralysis. [Corrie Driebusch, Wall Street Jounral, Jun 11, 17]
Google-owner Alphabet has agreed to sell robotics firm Boston Dynamics (Waltham, MA; $3.2M SBIR) to SoftBank, the Japanese telecommunications and technology company. Terms of the deal remain undisclosed. ... That Alphabet has finally sold its most high-profile robotics subsidiary may signal an end to the company’s passing flirtation with the world of humanoid and industrial robots. .... As part of the SoftBank deal, Alphabet is also selling Schaft, a humanoid robotics company Google acquired as part of its Replicant buying spree back in 2013 and 2014. Schaft was spun out of the JSK Robotics Laboratory within the University of Tokyo. [theverge.com, Jun 9, 17]
Sedia Biosciences (Portland, OR; at least $3M SBIR) has laid the groundwork with its test that determines how recently someone has been infected with HIV. Its new test will be able to give the result in just 20 minutes. [Elizabeth Hayes, Portland Business Journal, Jun 7, 17]
Citing a shrinking labor force and a growing worldwide demand for food, Abundant Robotics (Hayward, CA; no SBIR) is off to a good start in the apple-picking business. The company has designed intelligent robots capable of determining whether apples are ready to pick, day or night, and carefully picking them using a gentle vacuum technology rather than a standard claw- or hand-like mechanism. Abundant Robotics recently raised $10 million in an investment round led by GV (formerly Google Ventures), which will help the company develop robots that can harvest other foods. [cybertrend.com, Jun 1, 17]
Everspin Technologies (Chandler, AZ; one SBIR) up 18% [Jun 8,17]
NewLink Genetics down 41% [Jun 8,17] announced that Genentech, a member of the Roche Group, informed NewLink Genetics that it intends to return the rights to IDO inhibitor GDC-0919 (navoximod) pursuant to the License Agreement dated October 16, 2014. [company press release, Jun 8, 17]
Platelet BioGenesis (Boston, MA; no SBIR) startup spun out of Harvard lab, developing a process to produce life-saving human platelets from stem cells, announced it has raised $10 million in Series A. [company press release, Jun 8, 17]
Acera Surgical (Creve Coeur, MO; no SBIR), a medical device startup born out of Washington University, has reported raising [$600K] of a $4 million debt and option offering. [Brian Feldt, St. Louis Business Journal , Jun 5, 17] commercializing a portfolio of fully synthetic electrospun scaffolds for regenerative medical applications. [company website]
Apse (St Louis, MO; one SBIR) raised $464K seed capital. [crunchbase.com, Jun 5, 17] developed technology that will allow the cost efficient production of RNA for broad acre topical RNAi uses in agriculture. [company website]
Seattle Genetics tees up another application of its flagship drug that could net $100M [Puget Sound Business Journal, Jun 7, 17] .... Takeda Pharmaceutical and Seattle Genetics announced that data from the randomized Phase 3 ALCANZA clinical trial evaluating ADCETRIS (brentuximab vedotin) in patients with cutaneous T-cell lymphoma (CTCL) were published in the journal Lancet. [joint companies press release, Jun 7, 17]
NanoString Technologies (Seattle, WA; no SBIR, 450 employees), a provider of life science tools for translational research and molecular diagnostic products, announced the closing of its previously announced underwritten public offering of ... approximately $56.5 million. [company press release, Jun 6, 17]
Cash for spinouts. University of Pittsburgh Chancellor Patrick Gallagher’s efforts to hotwire the region’s fledgling life sciences industry is getting a spark from a new seed capital fund targeted to helping develop new medications. The Pittsburgh Revolution Fund is soliciting $200 million, which will be made available in the form of investments in drug research teams with the idea of spinning out companies, said Bill Newlin, chairman, Newlin Investment Co., a seed-stage investment firm [Kris B. Mamula, Pittsburgh Post-Gazette, May 30, 17]
Scattered and incalculable. One might expect that over that amount of time, the Department of Defense would have developed a system to become compliant with SBIR’s fundamental provision that a minimum threshold of innovation research spending be directed toward small businesses. Yet, a new report from the Government Accountability Office concludes DOD couldn’t say if it was meeting the threshold because, DoD did not submit the required obligations data. The report states “DOD officials told [the GAO] that obtaining obligations data would require requesting information from more than 10 individual program offices that, in turn, would have to request the information from various DOD comptrollers, which would be a major effort.” [SSTI, Jun 7, 17] Each sub-agency of DOD has its own incentives to short-change SBIR in favor of spending its R&D money its its main purposes. But the politicians seem to care for nothing about SBIR except handing the mandated amounts to the small biz political constituents.
bluebird bio up 11% [Jun 7,17]
Editas Medicine up 10% [Jun 7,17]
Fluidigm down 11% [Jun 7,17]
Lung Therapeutics (Austin, TX; no SBIR, at least $1.7M NIH grant), a clinical stage pharmaceutical company developing novel therapeutics for niche, orphan drug indications in fibrosis, lung injury and disease, announced the successful completion of a $14.3 million Series B financing. The proceeds will support ongoing LTI-01 clinical trials in Australia and New Zealand, as well as development activities to advance the Company's transformative drug for fibrosis, LTI-03. The total outside funding Lung Therapeutics has raised is now $17 million. This is in addition to the $27M in non-dilutive funding awarded for discovery research and development for both drug candidates. [company press release, Jun 6, 17]
Dova Pharmaceuticals (Durham, NC; no SBIR, founded 2016, four employees), focused on developing drugs to treat low blood platelet counts, is attempting to raise as much as $75 million through an IPO. .... one promising drug candidate called avatrombopag, which it acquired from the Japanese pharmaceutical company Eisai in March 2016 [Zachery Eanes, Raleigh News & Observer, Jun 7, 17]
CardioNXT (Westminster, CO; no SBIR, founded 2012) medical device company raises $2.1M for atrial fibrillation tech ... Total Equity Funding: $3.6M [innovationews.com, Jun 2, 17] ... has built a platform of products that enable a better understanding of complex cardiac arrhythmias [crunchbase.com]
Neuronetics (Malvern, PA; no SBIR) maker of non-invasive depression [mgnetic] treatment system raises $15M [John George, Philadelphia Business Journal, Jun 7, 17] NeuroStar TMS Therapy is indicated for the treatment of Major Depressive Disorder in adult patients who have failed to receive satisfactory improvement from prior antidepressant medication in the current episode. [company website]
Trice Medical (King of Prussia, PA; no SBIR) announced that it closed a $19.3 million Series C and will use the proceeds to accelerate and expand the company’s U.S. market penetration for mi-eye2™, R&D, sales, marketing and key international regulatory approvals. ... received FDA 510(K) clearance during the fourth quarter of 2016, has captured the attention of medical professionals who are embracing the technology as a replacement to the MRI [company press release, Jun 6, 17]
Economic dream. Trump has plans, and promise, to create a "first-class" system of roads, bridges and waterways by using $200 billion in public funds that he says will generate $1 trillion in investment to pay for construction projects that most public officials agree are badly needed and long overdue. [San Jose Mercury News, Jun 7, 17] Private invesors, though, don't do it for politics, only for profit, which is hard to come by from road and bridges. If it were a good investmnt, we would already have a lot of it. Even The Donald would have invested in it. Now we shall see how persuasive he is with private investors as he tweets his way to fame and fortune for public goods. Stand by for rip-off stories as private firms take public money controlled by politicians.
CTI Biopharma down 20% [Jun 6,17]
Contract drug manufacturer and research company Albany Molecular Research (Albany, NY; $800K SBIR) said it had agreed to be taken private by buyout firms Carlyle Group LP and GTCR LLC for about $922 million in cash. [Divya Grover, Reuters, Jun 6, 17]
Athenex (Buffalo, NY; no SBIR) hopes to raise about $72 million in IPO [Buffalo Business First, Jun 6, 17]
Lumisyn LLC (Rochester, NY; three prior SBIRs, founded 2014) received a $1 million [Phase II SBIR] from the U.S. Department of Energy ... will work to double the efficiency of LED lights [Kerry Feltner, Rochester Business Journal, Jun 6, 17] develops high-performance cadmium-free phosphors to enhance lighting and optoelectronic products. [company website]
Novan (Morrisville, N.C; $3.5M SBIR) makes wholesale managment shifts. To be exceedingly clear, the Company will require additional capital in order to proceed on broadening the potential application of the science (nitric oxide) and the underlying technology, and specifically to initiate and complete the planned phase 2 trials in both psoriasis and atopic dermatitis. ... Creating a longer term “runway” for the overall Novan business remains a central imperative for the executive management team and the Board of Directors. [company press release, Jun 5, 17]
Retroactive cancellation. In January, the Department of Homeland Security announced 31 winners in a controversial grant program to fight violent extremism. A team lead by UNC-Chapel Hill researchers won the largest – nearly $900,000 to develop information campaigns to counter jihadist and white supremacist recruiting. ... and so far the Trump administration has refused to release the money. ... A spokesman for the Department of Homeland Security wrote in an emailed statement that it’s unclear whether the money will be released. He declined to say why the department hasn’t sent it. .... Congress, though, has already approved the grant program for the current fiscal year. [Jay Price, WUNC Radio, Jun 5, 17] Politics or incompetence? In the chaos of Trump's fumbling administration, almost any explanation could be true.
Pay some, stiff others. [OMB Director] Mulvaney said, “You cannot meet all of your obligations as a nation; that’s not a desirable outcome.” However, he added, there is “absolutely no way” the U.S. would default on Treasury securities. “We are not going to do that. You can take that off the table,” Mulvaney vowed. What’s likely to trouble the financial markets in that statement is the distinction Mulvaney makes between payment to debtors who hold Treasury securities and all other payments -- from Social Security checks to the federal payroll to bills from government contractors. [Rob Garver and Eric Pianin, Fiscal Times, Jun 5, 17] The message: Rich US bond holders will get paid but poor Social Security recipients will have to compete with all other government bills for underpayment or outright default. Our new president is reportedly quite adept at not paying the full bill for services and his OMB chief is ready to arbitrarily default on obligations enacted in law.
Back toward sane government. Kansas legislators repudiated the tax-cutting experiment that brought Gov. Sam Brownback national attention, with even fellow Republicans voting to override his veto of plan reversing many of the income tax reductions he's championed in recent years as a way to fix the cash-strapped state's budget. [JOHN HANNA, AP, Jun 6, 17]
Dynavax up 17% [Jun 5,17]
NewLink Genetics down 12% [Jun 5,17] announces the presentation of results from a randomized Phase 2 investigator initiated study with indoximod in combination with the therapeutic cancer vaccine, PROVENGE (sipuleucel-T), for patients with metastatic castration resistant prostate cancer. [company press release, Jun 5, 17]
Juno Thera down 11% [Jun 5,17]
XBiotech down 10% [Jun 5,17]
The Stago group (France) announced that it has completed the acquisition of HemoSonics LLC (Charlottesville, VA; $700K SBIR), a company specialized in the development of innovative Point-of-Care testing solutions... With the acquisition of the patented SEER technology (Sonic Estimation of Elasticity via Resonance) and its associated QuantraTM Hemostasis Analyzer, Stago demonstrates its willingness to develop a Point-of-Care offering to complete its leadership in Haemostasis testing and beyond. [Stago press release, May 30, 17] HemoSonics has been awarded more than $8 million in grants from the [several, mostly USG] institutions [HemoSonics website]
After a big stock bump from positive trials results, Duke University spinout Aerie Pharmaceuticals announced it’s raised another $125M. [Jennifer Henderson, Triangle Business Journal, May 26, 17]
A transformative event. Mr Trump has revolutionized our ideas of what the US stands for. We live in the world the US made. Now it is unmaking it. We cannot ignore the grim reality. ... Hard power and lower taxes: these are the US priorities under Mr Trump. [Martin Wolf, Financial Times, May 31, 17]
So in love with the sound of his own voice speaking power: Trump may have irretrievably undermined his lawyers’ efforts to persuade the Supreme Court to reinstate his executive order limiting travel from six predominantly Muslim countries. Saying he preferred the original travel ban, “not the watered down, politically correct version” he had issued in March, Trump attacked both the Justice Department and the federal courts. [Adam Liptak and Peter Baker, New York Times, Jun 6, 17]
TG Therapeutics up 17% [Jun 2,17]
Achillion Pharma up 12% [Jun 2,17]
Stock prices of Editas Medicine, CRISPR Therapeutics (Switzerland), and Intellia Therapeutics (Cambridge, MA; no SBIR) dropped sharply after the publication of a Nature Methods article that described unintended effects stemming from the use of CRISPR-Cas9 gene-editing technology. But as Xconomy noted two years ago, the possibility of “off-target effects” from use of these tools have long been a concern. [Ben Fidler, xconomy.com, Jun 2, 17]
Intuitive Surgical (Sunnyvale, CA; $2.4M SBIR) won FDA clearance for the da Vinci X Surgical System, the latest iteration of its robotic-assisted surgery platform, and will launch it the U.S. later this year. [Ben Fidler, xconomy.com, Jun 2, 17]
ImmunoGen got $30 million from Sanofi to amend a 2003 deal and give up its right to co-promote a group of experimental cancer drugs in the U.S. [Ben Fidler, xconomy.com, Jun 2, 17]
Array Biopharma will get $31.6 million up front in a deal with Ono Pharmaceutical for partial rights to two of the Boulder, CO, biotech’s cancer drugs. [Ben Fidler, xconomy.com, Jun 2, 17]
Endocyte (West Lafayette, IN; $3.5M SBIR) is halting a clinical trial for one of its cancer drugs and narrowing the focus of another following a review of the two early-stage drug programs, the company announced. The changes are sparking a corporate restructuring that will shift the company’s focus to compounds in its drug pipeline that have yet to enter clinical trials. Endocyte said in a securities filing that the shakeup will cut 47 jobs companywide, which represents approximately 40 percent of the workforce. [Frank Vinluan, xconomy.com, Jun 2, 17]
Mayo Clinic secured a big potential stock ownership position in Twin Cities-based medical device startup BioSig Technologies (Minneapolis, MN; no SBIR) in connection with a long-term research collaboration with the Rochester institution and its licensing arm, Mayo Clinic Ventures ... in the development of its PURE electrophysiology (EP) platform, which uses proprietary technology to filter out electromagnetic interference from equipment in a typical EP lab. [Don Jacobson, Twin Cities Business, May 31, 17]
Monteris Medical (Plymouth, MN and Winnipeg, Manitoba; no SBIR) announced the recent completion of a Series C financing, raising $26.6M in new equity. ... leader in the market for minimally invasive, MRI-guided laser ablation systems for treating brain lesions. ... currently markets the NeuroBlate® System in the United States and Canada as a surgical tool that provides neurosurgeons an alternative to traditional craniotomies. [company press release, Jun 1, 17]
Mersana Therapeutics (Cambridge, MA; no SBIR, founded 1999, 75 employees) has filed for [$75M IPO] that would help fund clinical trials for the company’s experimental treatment for breast cancer. ....is developing antibody drug conjugates (ADCs), a type of cancer drug that links antibodies to cancer-fighting toxins. This approach uses antibodies to deliver a targeted strike to tumors that’s meant to spare healthy tissue from the treatment’s toxic effects. .... In 2014, Mersana began a research partnership with Japan-based Takeda Pharmaceuticals to develop ADCs targeting up to seven antigen targets selected by Takeda. So far, Mersana has received $24.8 million in payments from that deal. If the collaboration successfully produces seven commercialized drugs, the company stands to gain milestone payments topping $1 billion. [Frank Vinluan, xconomy.com, Jun 2, 17]
Vertera Spine (Atlanta, GA, at least one SBIR) raised more than $3 million, according to [SEC] documents [Ellie Hensley, Atlanta Business Chronicle, May 31, 17] to address the unmet clinical need for improved spinal fusion solutions by developing and commercializing fusion devices using patented porous PEEK technology. [company website]
ARPA-E intends to issue a Funding Opportunity Announcement (FOA) for the development of hybrid fuel cell and engine systems for the ultra-high efficiency conversion of natural gas to electricity. The objective of this FOA will be to encourage the development of commercial-scale (>100 kW) Distributed Generation (DG) systems that have fuel-to-electric power conversion efficiencies in excess of 70% on a Lower Heating Value (LHV) basis. [ARPA-E Newsletter: June 2, 2017]
Technology will leave few segments of the labor market untouched .... while machines with rudimentary artificial intelligence capabilities are already writing basic news stories .... The [worry] is that Americans will embrace a still more radical politics that threatens to compound the damage. Already, both parties are flirting with populist “quick fix” remedies. ... A bipartisan new deal would instead be premised on helping individuals to acquire the education and skills they need to prosper in a fast-changing economy. [Edward Alden and Robert Litan, Council for Foreign Relations, May 31, 17] People with short attention spans and declining education standards call for quick fixes to any problem.
Everyone's on their own. It was put most succinctly this week by two Trump advisers, H.R. McMaster and Gary Cohn, when they wrote in the Wall Street Journal that “the world is not a ‘global community’ but an arena where nations, non-governmental actors and businesses engage and compete for advantage...Rather than deny this elemental nature of international affairs, we embrace it.” [The Economist, Jun 3, 17] Trump apparently requires his "advisors" to promote his opinions without regard to the advisors' earned reputation for strategic thinking and respect for facts.
Weeks before Trump made the announcement on the Paris accord, it was clear the debate inside the White House on the issue was "content free" and purely political, Forign Policy's Robbie Gramer and Dan De Luce reported. And the [climate is a security problem] views of [SECDEF] Mattis and others in the national security establishment were not solicited. [Foreign Policy sitrep, Jun 2, 17]
XBIOTECH up 27% [Jun 1,17] Presents Phase III Findings for its Antibody Therapy for Colorectal Cancer ... Data Show Reduced Disease Progression and Improved Survival for Patients Achieving Primary Endpoint [company press release, Jun 1, 17]
Cellular Biomedicine up 24% [Jun 1,17] announced the Company's approved a new stock repurchase program granting the company authority to repurchase up to $10 million in common shares [company press release, Jun 1, 17]
Minerva Neurosciences up 21% [Jun 1,17] announced that Minerva and Johnson & Johnson entered into a binding term sheet to amend that certain Co-Development and License Agreement between Minerva and [JNJ sub] Janssen Pharmaceutica NV, related to the Company's MIN-202 product candidate. Minerva has also agreed to repurchase all Minerva stock held by J&J at a per share price of $0.0001. .... JNJ to make an upfront payment to Minerva of $30 million [company press release, Jun 1, 17]
HTG Molecular Diagnostics up 13% [Jun 1,17]
Senseonics Holdings (Germantown, MD; no SBIR) a medical technology company focused on the development and commercialization of Eversense®, a long-term, implantable continuous glucose monitoring (CGM) system for people with diabetes, announced the pricing of its underwritten offering expected to be $41.0 million. [company press release, May 26, 17]
Bicycle Therapeutics (Cambridge, UK and Cambridge, MA) is developing a new class of drugs that it says can offer a more targeted approach, and it has raised $52 million [Series B]to support plans to bring its lead drug into clinical trials. ... claiming that its drugs combine the advantages of other types of drugs. Large molecule drugs, made from proteins, offer the ability to bind to specific sites on a cell’s surface. But their large size keeps them from penetrating the cell itself. Meanwhile, the size of small molecule drugs allows them to reach almost anywhere in the body, and including the inside of cells [Frank Vinluan, xconomy.com, Jun 1, 17]
Dr. Canfield leads Siwa Biotech (Oklahoma City, OK, one SBIR in 2008, founded 2005), which is advancing a technology to ensure that people having blood transfusions receive the correct blood type. OCAST has provided funding for Siwa just as it did for Canfield’s earlier research [OCAST $150K grant in 1991 fueled groundbreaking research into causes of often fatal enzyme deficiency conditions such as Pompe disease] that became Novazyme (no SBIR, acquired by Genzyme for $206M in 2001) [Oklahoma OCAST 2017 Impact Report, May 2017]
Medical-robotics maker Myomo (Cambridge, MA; one SBIR in 2007) is taking a shortcut to go public for $15M. ... is tapping Reg A+, a provision of the Jumpstart Our Business Startups Act, a 2012 law designed to help fund small-business growth and increase employment by removing some hurdles for companies trying to go public. Reg A+ allows companies to raise up to $50 million by pitching their IPOs to all investors—not just those with a certain net worth or income—in fast-tracked deals. [Corrie Driebusch, Wall Street Journal, Jun 1, 17]
The Kauffman Foundation’s recently updated Index of Startup Activity finds that startup activity has increased for the third consecutive year and has now reached pre-recession levels. Nationally, the index, which measures business startup activity from 1997 to 2016, increased moderately after two years of sharp growth. [SSTI, May 31, 17]
The Department of Homeland Security announced that it would not be implementing a ban on laptops and other electronic devices on flights to the United States from Europe. Whether the U.S. government will pursue a rule like this in the future remains uncertain [Crain's Washington DC, Jun 1, 17]
Catalyst Biosciences up 13% [May 31,17]
Cleveland Biolabs up 13% [May 31,17]
Exact Sciences (Madison, WI; no SBIR) up 12% [May 31,17] on news that the health insurer UnitedHealthcare will cover Cologuard, Exact’s stool-based DNA test for colorectal cancer, starting July 1. [Jeff Buchanan, xconomy.com, May 31, 17]
Grail (Menlo Park, CA; no SBIR), the Illumina spinout aiming to develop a blood test that can detect cancer at its earliest stages, has gone global. The , startup, is merging with China’s Cirina (Hong Kong, founded 2014) co-founded by a pioneer in the field of blood-based diagnostics, Dennis Lo [the first to discover that bits of fetal DNA circulate in a pregnant mother’s blood]. ... [Grail] recently raised a record $900 million round from a group of drugmakers and others, didn’t disclose the financial terms of the merger. [Ben Fidler, xconomy.com, May 3, 17]
Arcturus Therapeutics (San Diego, CA; no SBIR, founded 2013) said a leading RNA medicines company, announced that it has entered into a research agreement with Cystic Fibrosis Foundation Therapeutics Inc. (CFFT), the nonprofit drug discovery and development affiliate of the Cystic Fibrosis Foundation in which CFFT will pay up to $3 million to advance LUNAR-CF, a novel messenger RNA (mRNA) therapeutic formulated with Arcturus' LUNAR™ delivery technology. .... The company owns LUNAR™ nanoparticle delivery and unlocked nucleomonomer agent (UNA) technology including UNA Oligomers, which are covered by its patent portfolio (80 patents and patent applications, issued in the U.S., Europe, Japan, China and other countries). [company press release, May 30, 17]
Array BioPharma and pharmaceutical giant Bristol-Myers Squibb will test the effectiveness of Array’s drug binimetinib in combination with a Bristol-Myers’ immunotherapy drug as a treatment for some kinds of colorectal cancer [Greg Avery, Denver Business Journal, May 30, 17]
Snake oil state. Lawmakers in Austin have approved a bill authorizing unapproved stem cell therapies, putting Texas on track to become the first state to explicitly recognize the experimental treatments. [Andrew Joseph, statenews.com, May 30, 17] You could be an experiment in over-promising ventures.
A watchdog site calling out academic publishers for incorrectly charging readers for open access papers is gaining momentum. The site, Paywall Watch, tracks papers published in open access (OA) journals that are supposed to make content freely available online but instead appear behind a paywall for readers. [Dalmeet Singh Chawla, the Scientist, May 31, 2017]
a golden rule: When the product is free, that means you are the product. Your privacy is the cost of a free social network, free tax prep or free photo storage. [Geoffrey A. Fowler, Wall Street Journal, May 31, 17]
Ultralife up 10% [May 29,17]
Editas Medicine down 10% [May 29,17]The Pentagon conducted a successful test of a system designed to shoot down an intercontinental ballistic missile : ICBM from southern Pacific, interceptor from California.
Cellular Biomedicine Group up 13% [May 26,17]
BioCryst Pharma down 14% [May 26,17]
Symic Bio (Emeryville, CA; at least $1.5M SBIR in 2015) a biopharmaceutical company developing novel matrix regulator therapeutics, announced the successful completion of a $30 million Series B financing and provided a program update regarding lead program SB-030. ... to support clinical programs including SB-030 in the prevention of peripheral vein graft failure and SB-061 for pain management and disease modification in the treatment of osteoarthritis of the knee [company press release, May 22, 17]
Harpoon Therapeutics (South San Francisco, CA; no SBIR, founded 2015) raised $45 million in a Series B round of funding to bring two cancer immunotherapies into clinical trials. .... Harpoon’s first clinical candidate, HPN424, is a prostate-specific membrane antigen (PSMA)-targeting TriTAC™. HPN424 is in development for the treatment of metastatic prostate cancer and is expected to enter Phase 1 clinical trials in 2018. The company anticipates additional clinical candidates to be identified and move into development within the next year [company website, May 26, 17]
If a new version of an antibiotic of last resort lives up to its promise, that date with doom may be averted. A study on this bolstered form of vancomycin by scientists at The Scripps Research Institute in La Jolla was released Monday. ... three modifications to vancomycin, all lethal to bacteria and independent of each other. ... The study was published in the Proceedings of the National Academy of Sciences. .... Once made available online, the report can be found at j.mp/bogervanco. [Bradley Fikes, San Diego Union Tribune, May 29, 17]
OrphoMed (Mill Valley, CA; no SBIR), a clinical stage biopharmaceutical company developing first-in-class dimer therapies, announced the completion of a $39 million Series A financing [co-led by existing seed investor Takeda Ventures]... to advance the clinical development of OrphoMed’s lead candidate, ORP-101, for the treatment of irritable bowel syndrome with diarrhea (IBS-D). [company press release, May 24, 17].
Qualcomm is asking a federal judge to order four companies that build Apple’s iPhones and iPads to resume paying cellular patent royalties while the two tech giants wage legal war over the value of intellectual property. [Mike Freeman, San Diego Union Tribune, May 25, 17]
Debiopharm International SA (Switzerland) and Immunogen (Waltham, MA, $1.6M SBIR in 1990s, founded 1981), a leader in the expanding field of antibody-drug conjugates (ADCs) for the treatment of cancer, announced that Debiopharm has acquired ImmunoGen's IMGN529/DEBIO 1562, a clinical-stage anti-CD37 ADC for the treatment of patients with B-cell malignancies, such as non-Hodgkin lymphomas (NHL). ... ImmunoGen received a $25 million upfront payment for IMGN529/DEBIO 1562 and is entitled to a $5 million milestone payment to be paid after completion of the transfer of ImmunoGen technologies related to the asset, which the parties expect to achieve by the end of 2017. In addition, ImmunoGen is eligible for a second success-based milestone payment of $25 million upon IMGN529/DEBIO 1562 entering a Phase 3 clinical trial. [joint companies press release, May 23, 17]
The DeSoto County [CA] Board of Supervisors approved 10-year partial property tax incentives for Intuitive Surgical on May 15. [Elle Perry, Memphis Business Journal, May 19, 17]
BayoTech (Fort Collins, CO; no SBIR, founded 2015), a biotechnology startup announced as the first business to receive money from the $20 million Catalyst Fund. .... licensed its technology from Sandia National Laboratories for $50 million about three years ago, which Eisenach said has made their goal of creating an affordable hydrogen economy a reality. [May Ortega, Albuquerque Business First, May 22, 17] raised a $1.5 million Series A funding round as it works to develop a smaller, more cost-effective system for manufacturing nitrogen fertilizer. [company press release, Sept 2016]
China is investing billions of dollars into growing its own biotechnology industry. ... Li Yan, general manager of Qilu Pharmaceutical was here to preside over her company’s opening of the area’s first Chinese-owned biotech incubator: the Qilu (pronounced chee-lew) Boston Innovation Center. The new 25,000-square-foot center in Brighton eventually could house up to 10 early-stage drug discovery companies in its sparkling first-floor labs [below] home office and research center of QLB Biotherapeutics startup that is an arm of the big Chinese drug maker. [Robert Weisman, Boston Globe, May 26, 17]
[John Boehner] said a repeal and replacement of the Affordable Care Act is "not going to happen. Republicans never ever agree on health care." Twenty four million people will not give up their health insurance for the sake of a few thousand billionaires [who don't need health insurance] paying less tax for social insurance in a tax cut bill pretending to be a healthcare plan.
Aerie Pharma up 34% [May 25,17] a clinical-stage pharmaceutical company focused on the discovery, development and commercialization of first-in-class therapies for the treatment of patients with glaucoma and other diseases of the eye, today announced that it has commenced a registered underwritten public offering of $50 million of shares of its common stock. [company press release, May 25, 17]
BioCryst Pharma up 31% [May 25,17] Reports Additional Positive Results From the Second Interim Analysis of Its APeX-1 Trial. 125 mg dose of BCX7353 showed a reduction of 73% in overall attack rate (p=0.002) [company press release, May 25, 17]
GTx (Memphis, TN; $300K SBIR in 2003) down 22% [May 25,17]
Cellular Biomedicine Group down 10% [May 25,17]
EnteroMedics (St Paul, MN; no SBIR), the developer of medical devices treating obesity, metabolic diseases and other gastrointestinal disorders, announced today that it has acquired the Gastric Vest System™ (the "Gastric Vest" or "Vest"), through its acquisition of BarioSurg (Lake Forest, CA; no SBIR, founded 2008) [for stock and $2M cash]. The Gastric Vest is an investigational, minimally-invasive, laparoscopically implanted medical device being studied for weight loss in morbidly obese patients. [Enteromedics press release, May 23, 17]
Nitride Solutions (Wichita, KS; no SBIR, founded 2009), a leading developer and manufacturer of advanced nitride substrates for LEDs, lasers, and power electronics, announced that it has successfully closed $2.75M in new funding. ... to ramp up manufacturing capacity and staffing to meet rapidly growing customer demand for the company’s aluminum nitride products [company press release, Apr 24, 17]
Sciaderm (Paoli, PA; no SBIR) received part of a $575K grant to three firms from Ben Franklin Partners of Southestern PA .... is developing a new and novel treatment for psoriasis with a mode of action that is different from other treatments currently in use. [Ben Franklin press release, May 17, 17]
Cleveland Biolabs up 17% [May 23,17]
EntertMedics up 11% [May 23,17]
Sangamo Thera up 10% [May 23,17]
Fluidigm down 10% [May 23,17]
Qualcomm
demonstrated its vision
of dynamic
electric vehicle charging on a test track in France, showcasing that
progress is being made toward recharging while in motion.
Using
its Qualcomm Halo wireless electric vehicle charging system, the San
Diego company said it charged Renault Kangoo electric vehicles on a
100-meter test track at highway speeds, delivering 20 kilowatts of
power along a track. ... The 100 meter test track used in
last
week’s demonstration costs $10.1 million, which was funded mostly by
the European Commission. [Mike Freeman, San
Diego Union
Tribune, May 22, 17] QTI
has designed, built, and tested a DEVC system capable of charging an EV
dynamically at, and in excess of, 100 km/h with 20 kW. Even better,
we’ve done this with not just one vehicle but two — charging them
simultaneously. [Qualcomm press release. May 18,
17]
ViaCyte (originally Novocell, San Diego, CA; no SBIR) said it is ready to move into human testing with a new product intended for patients with Type 1 diabetes who are at high risk for acute, life-threatening complications from severe episodes of low blood sugar (hypoglycemia). ... said it has raised an additional $10 million to initiate the clinical trial and for other corporate purposes [Bruce Bigelow, xconomy.com, May 22, 17]
BGI (China) announced the launch of a West Coast Innovation Center, co-located in Seattle and San Jose. .... Seven years ago, BGI began its bid to turn China into a DNA superpower by buying 128 of the world’s fastest sequencing machines—then the Illumina HiSeq 200. That made BGI Illumina’s biggest single customer at the time, and an overnight sequencing sensation. .... Last March, almost exactly a year after Obama announced a $215 million initiative to sequence 1 million Americans, China finalized its plans for a much bigger, multi-billion dollar project. [Megan Molteni, Wired, May 18, 17] A Chinese company [A U.S. subsidiary of BGI-Shenzhen] will buy human genome sequencing company Complete Genomics (no SBIR, IPO 2010) for $113 million and provide $30 million in bridge financing for operations after signing a merger agreement. [Ron Leuty, San Francisco Business Times, Sep 17, 12]
Economics trumps Trump. More than 600 Carrier employees in Indianapolis will soon be out of a job. ... Last year, the company originally said it planned to move its entire operation to Mexico, laying off more than 1,000 Hoosiers. Last fall, President Trump struck a deal with Carrier to save many of those jobs. [Indianapolis Star, May 22, 17] As Trump knows and does at home, economics tops politics for profit-making corporations.
Made America great. [billionaire biotech investor Gerald] Chan said investments in basic science are paying off for many Asian countries, which have been “unsparing” in pouring money into that sector. “Slowly but surely, they are chipping away at America’s commanding lead in science, which was part and parcel of the post-World War II world order,” Chan said. “If we are to make America great again, let us never forget what made America great in the first place,” he told the audience, [Bradley Fikes, San Diego Union Tribune, May 19, 17]Trump's energy plan: more oil, less R&D. heavily influenced by the Heritage Foundation, a conservative think tank that argues that the federal government should fund only very basic scientific research and get out of the business of helping companies commercialize new energy technologies. ... Office of Energy Efficiency and Renewable Energy, which has helped nudge down the cost of solar power, faces a 69 percent cut. The Office of Fossil Energy, which invests in methods for capturing carbon dioxide from coal plants and burying it underground, faces a 54 percent cut. The Office of Nuclear Energy, which is pursuing technology to help extend the life of the United States’ existing nuclear reactors, faces a 31 percent cut. [BRAD PLUMER and CORAL DAVENPORT, New York Times, May 23, 17] Chances in Congress? Nil.
Applied Optoelectronics up 12% [May 22, 17]
Finisar (one SBIR) up 10% [May 22, 17]
Cellular Biomedicine down 12% [May 22, 17]
Sharklet Technologies (Aurora, CO; one SBIR) lauded for the creation and commercialization of Sharklet®, the world’s first micro-texture that inhibits bacterial growth on surfaces, announced that it has completed a financing event led by Peaceful Union, [Chinese] medical device firm. ... The acquisition of the company will enable Sharklet Technologies to accelerate the development of Sharklet for medical devices where chemical-free bacterial inhibition is desired as well as high-touch surfaces prone to bacterial contamination. [company press release, May 15, 17]
The Trump
administration says it
can balance the federal budget within a decade. Its blueprint calls for
significant cuts to social safety net programs and assumes more robust
economic growth [with] what it calls a "Taxpayer First"
budget.
... the first time in a long time that an administration has written a
budget through the eyes of the people who are actually paying the
taxes,” said Trump’s budget director. [npr,
May 22,
17]
Look for the
entitlements clause that allows the rich to sleep under the
bridges. It's consistent with Trump's lifelong approach to
deals:
ask for more than everything. He did suggest in his campaign
that
even Treasury bond-holders could also be asked to take less than their
due. He will find that government doesn't work like a family private
entity, especially when the other party can fire him.
Cells without walls. Synvitrobio (Berkeley, CA; no SBIR) accelerates bio-discovery through cell-free systems. Synvitrobio's Next Generation Expression platform allows for high-throughput data collection that is real and experimentally validated - not simulation. ... At present, Synvitrobio is using its system to test DNA sequences (or, rather, the resulting proteins) to see if they might be worth investigating as antibiotic drugs. ... Sutro Biopharma (South San Francisco, CA; no SBIR) uses a cell-free system to create antibodies for the treatment of cancer. ... Genomatica (San Diego, CA; $6M SBIR) , an established biotechnology firm based, is experimenting with a cell-free system which produces 1,4-butanediol in this way from simple sugars. 1,4-butanediol is a small molecule that is used to make polymers such as Lycra. .... GreenLight Biosciences, (Medford, MA; no SBIR) proposes to use its own cell-free system, also based on E. coli, to produce industrial quantities of an undigestible analogue of ribose, a naturally occurring sugar, for use in zero-calorie beverages .... the idea of stripping molecular biology down to its bare essentials has an efficiency about it which suggests that, for some applications at least, the utility of the biological cell may have run its course. [The Economist. May 6, 17
Ionis Pharmaceuticals touted Phase 3 results for its rare nerve disease drug, inotersen, and said it plans to file for FDA approval. But investors noted safety concerns and sent Ionis shares down while boosting rival Alnylam Pharmaceuticals [Ben Fidler, xconomy.com, May 19, 17]
Vifor Pharma made a $50 million equity investment in Akebia Therapeutics at $14 per share. The deal gives Akebia license to sell its anemia pill vadadustat, upon FDA approval, at Fresenius Medical Care dialysis clinics in the U.S. Vadadustat and rival roxadustat from Fibrogen are both in Phase 3 testing. [Ben Fidler, xconomy.com, May 19, 17]
Stem Pharm (Madison, WI; $300K [NIH] SBIR, founded 2015, two employees) is one of the newest startups to join the field. ... builds on research conducted in the laboratory of UW-Madison biomedical engineering professor Bill Murphy, is developing biomaterials capable of supporting stem cells as they grow. ... already shipping products to customers, such as materials that promote the self-assembly of cells into human tissues, Murphy says. [Jeff Buchanan, xconomy.com, May 19, 17]
Aqua Metals (Alameda, CA; no SBIR, founded 2014) has developed a more environmentally friendly and cheaper way to recycle lead acid from batteries using a low-temperature, water-based process. ... inventing a technology called AquaRefining, which recycles lead batteries without producing additional waste that ends up in landfills. Recycled batteries are broken apart by machines that separate the plastic from the lead. The plastic is recycled, while an electrochemical process rids the lead of impurities. .... IPO in 2015 raised $36 million. ... In February, Aqua Metals announced a global licensing and operation agreement with Johnson Controls, the largest lead acid battery company in the world. [Melissa Hellman, San Francisco Business Times, May 17, 17]
Maryland Technology Development Corp approved awards of $8.5 million to 29 new stem cell research projects. The for-profit firms each receiving over $1M are: TissueGene (Rockville, MD; $100K SBIR), Longeveron LLC (Miami, FL; no SBIR), MaxCyte (Gaithersburg, MD; $1M SBIR), Propagenix (Rockville, MD; no SBIR), Seraxis (Germantown, MD; no SBIR), and 3Dnamics (Germantown, MD; no SBIR). [Morgan Eichensehr, Baltimore Business Journal, May 16, 17]
OpGen (Gaithersburg, MA; no SBIR) received a written notification from The Nasdaq that it fails to comply with Nasdaq’s Marketplace Rule because the Company’s stockholders’ equity as of March 31, 2017 fell below the required minimum of $2,500,000 [marketexecutive.com, May 15, 17]
Only the best for only the richest. The first gene therapy treatment approved outside China is being pulled from the market because of a lack of demand. In 2012, European regulators approved Glybera to treat an ultrarare genetic disorder in which patients lack an enzyme called lipoprotein lipase that breaks down fats in the blood. But Glybera, which consists of viruses that insert a gene coding for the enzyme into muscle cells, cost $1 million a year, making it the most expensive drug in the world, and only one patient has had the treatment. Glybera's manufacturer, Amsterdam-based uniQure, said on 20 April that it would not seek to renew the drug's marketing approval when it expires later this year, noting that use “has been extremely limited.” Gene therapy observers say that more clearly effective gene therapies for diseases such as inherited immune disorders and hemophilia are still on track—although they, too, may come with eye-popping price tags. [Science, Apr 18, 17]
Giving the youngsters a break. NIH will start rationing grants to experienced investigators. In a May 2 announcement it plans to cap the number of grants an investigator can hold in order to free up funding for early-career scientists and those struggling to keep their labs afloat. It noted that numerous studies have found that as biomedical labs get bigger, their rise in productivity tapers off. The announcement did not touch on SBIR/STTR awards which may require Congressional action for such a change.
Achillion Pharma up 17% [May 18, 17]
Neuralstem up 16% [May 18, 17]
Immunigen up 14% [May 18, 17]
EnteroMedics up 11% [May 18, 17]
Immune Design up 11% [May 18, 17]
G1 Therapeutics up 11% [May 18, 17]
Cellular Biomedicine Group down 10% [May 18, 17]
Parents convinced FDA. After trial data for a new medicine proved inconclusive, Sarepta Therapeutics joined with the parents of sick boys to persuade officials it helped ... An FDA advisory committee voted 7-6 last year to oppose the drug’s approval, a position later overruled. ... Two weeks after the [2012] conference [on Duchenne muscular dystrophy] , the company made a 1-for-6 stock split, which raised its share price and allowed it to keep its Nasdaq listing. It also changed its name to Sarepta from AVI BioPharma. Sarepta shares have dropped back to $35. Some insurance companies refuse to cover the drug [at more than $300,000 a year]. A label on the medicine—renamed Exondys 51—says a clinical benefit of the drug “has not been established.” [Susan Pulliam and Brody Mullins, Wall Street Journal, May 18, 17]
Making blood. Scientists at Boston Children’s Hospital in Massachusetts successfully turned human stem cells into the cells that produce red and white blood cells and platelets. A team at Weill Cornell Medical College in New York City achieved a similar feat starting with mouse cells. Results decades in the making, they may one day help create blood transfusions in the lab. [MIT Technology Review, May 18, 17]
Kasparov now believes computers will take over menial mental tasks and thus allow humans to pursue ‘creativity, curiosity, beauty, and joy.’ [Robin Hanson reviews “Deep Thinking: Where Machine Intelligence Ends and Human Creativity Begins” by Garry Kasparov, Wall Street Journal, May 18, 17] Of course, the humans will still need a means of support to affiord their enriching pursuits.
Usual fantasy coming. Trump will propose the U.S. can balance the federal budget over 10 years with substantial cuts to safety-net programs such as food stamps and other anti-poverty efforts, combined with a tax and regulatory overhaul that speeds up the nation’s economic growth rate, a senior White House budget official said. [ Nick Timiraos, Wall Street Journal, May 19, 17] Mere fantasy: tax cuts will not jump start growth without great deficits [spending more money does raise economic activity], and the people's representatives will not slaughter benefits programs for any economic classes.
Fact check. "Obamacare is collapsing. It's dead. It's gone," Trump said in a news conference. "There's nothing to compare it to because we don't have health care in this country," ... In fact, we do have health care in this country — quite a lot of it. The U.S. spent about $3.2 trillion on health care in 2015, or nearly $10,000 per person. It accounts for 17.8 percent of GDP. [Alison Kodjak, NPR, May 18, 117]
Attention getter. The president skims reports quickly, and according to Reuters, “National Security Council officials have strategically included Trump's name in ‘as many paragraphs as we can because he keeps reading if he's mentioned,’” according to one official. [Foreign Policy sitrep, May 18, 17]
G1 Therapeutics (Research Triangle Park, NC; no SBIR, 31 employees) announced the pricing of its initial public offering for aggregate gross proceeds of $105M. ... developing novel, small-molecule therapies that address significant unmet needs in the treatment of cancer. The company is advancing a pipeline of potential best-in-class and first-in-class drug candidates in multiple oncology indications. [company press release, May 16, 17] The company’s revenues have so far only come from government grants related to research. [Zachery Eanes, Raleigh News & Observer, May 17, 17]
Congress hates failure. Technology giants, not the government, are building the artificially intelligent future. And unless the government vastly increases how much it spends on research into such technologies, it is the corporations that will decide how to deploy them. [Farhad Manjoo, New York Times, May17, 17] USG R&D is quite conservative, wanting predictable success that continues Congress's willingness to keep the money rolling. SBIR could have been a gateway to tech change, but Congress simply let handing out money to small biz take priority over innovation. Since innovation needs a lot of failures.
CVD Equipment (Central Islip, NY; $100K SBIR in 1987, 173 employees) up 12% [May 16,17]
Enteromedics down 28% [May 16,17]
Cellular Biomedicine Group down 10% [May 16, 17]
Synlogic (Cambridge, MA; no SBIR) is taking over the public listing [by reverse merger] from Mirna Therapeutics (Austin, TX; $700K SBIR) down 28% [May 16, 17] , a failed developer of cancer drugs in Austin, TX, that did not progress past Phase 1 trials. Synlogic shareholders will own 83 percent of the new company. About $40 million of the new cash comes from Mirna, and Synlogic is also raising $42 million in a Series C round of financing. The firm raised $70 million in its first two funding rounds, most recently in early 2016. [Alex Lash, xconomy.com, May 16, 17]
Goldman Sachs told investors to buy Intuitive Surgical shares because robot-assisted procedures will double in the next two years. [Tae Kim, CNBC, May 16, 17]
nLight (Vancouver, WA; $10M SBIR, 400 employees, founded Y2K) raised an additional $35 million to expand production, capitalizing on what the company says is a hot market for its technology. "We are growing, growing over 30 percent a year, over $100 million in sales last year," said Scott Keeney, nLight's founder and chief executive. [Mike Rogoway, The Oregonian. May 11, 17]
Cellular Biomedicine Group (Cupertino, CA and Shanghai, China; no SBIR) up 62% [May 15, 17], a clinical-stage biopharmaceutical firm engaged in the development of effective immunotherapies for cancer and stem cell therapies for degenerative diseases, today announced the addition of a new independent Phase I clinical trial of the Company's ongoing CARD-1 study in patients with chemorefractory and aggressive DLBCL. [company press release, May 15, 17]
Enteromedics up 31% [May 15,17]
Alnylam Pharma up 16% [May 15,17]
Immunogen up 11% [May 15,17]
Minerva Neurosciences up 11% [May 15,17]
Genoa Pharmaceuticals (Seattle, WA; no SBIR), focused on development of improved therapies for idiopathic pulmonary fibrosis (IPF) and other severe pulmonary indications, announced the completion of a $62 million Series A financing. [company press release, May 15, 17]
Sangamo Thera up 17% [May 12,17]
Ocular Thera up 15% [May 12,17]
Immucell up 11% [May 12,17]
Cleveland Biolabs up 10% [May 12,17]
Ischemic Care (Cincinnati, OH; $7.93M in 9 Rounds from 1 Investor) lands $2.3M [VC] is preparing a major clinical trial as it sets up to hit the market this year. ... commercializing a series of blood tests to stratify ischemic stroke and TIA patients by cause, leading to improved patient outcomes [crunchbase.com, May 13, 17]
Athenex (formerly Kinex Pharma $1.1M SBIR, Buffalo, NY and Hong Kong, founded 2003) filed with the [SEC] announcing that it plans to go public. [Dan Miner Buffalo Business First, May 13, 17] funded from inception by approximately $200 million in private financings and public-private partnerships with an estimated aggregate value of $375 million. ... dedicated to the discovery, development and commercialization of novel therapies for the treatment of cancer. [company website] announced it has received [FDA] allowance to proceed into human clinical trials with the combination of oral topotecan and its proprietary P-glycoprotein (P-gp) inhibitor HM30181A. [company press release, Mar 24, 17] Governor Cuomo announced a major expansion of Athenex that will create 1,400 jobs throughout Western New York. ... made possible by a partnership with the SUNY Polytechnic Institute, includes a major expansion of Athenex’s North American headquarters in Buffalo, as well as the creation of a state-of-the-art, 300,000 square foot manufacturing facility in Dunkirk. The combined projects are expected to yield a $1.62 billion investment over ten years from Athenex, along with $225 million from New York State. [company press release, Feb 11, 16]
Synthetic Biologics (Rockville, MD; no SBIR), a late-stage clinical company developing therapeutics that preserve the microbiome to protect and restore the health of patients, today announced that the [FDA] has granted a Breakthrough Therapy Designation for SYN-004 (ribaxamase) for the prevention of Clostridium difficile infection. [company press release, May 11, 17]
New National Laboratory Collaborations ... the U.S. Department of Energy announced the 38 small businesses that will collaborate with national lab researchers through the third round of the Small Business Vouchers (SBV) pilot. SBV facilitates access to the DOE national labs for American small businesses, enabling them to tap into the intellectual and technical resources they need to overcome critical technology challenges for their advanced energy products and gain a global competitive advantage. Eight DOE national laboratories will receive funding to partner with 38 competitively selected small businesses across the country. Visit the Energy Department's website www.SBV.org to read the whole story.
Sangamo Thera up 61% [May 11,17] Sangamo and Pfizer announced an exclusive, global collaboration and license agreement for the development and commercialization of gene therapy programs for Hemophilia A, including SB-525, one of Sangamo's four lead product candidates, which Sangamo expects will enter the clinic this quarter. ... Sangamo also reported a consolidated net loss of $16.6 million compared to a net loss of $16.5 million for the same period in 2016. [company press release, May 10, 17]
XBIOTECH down 10% [May 11,17]
Church & Dwight, the parent company of Arm & Hammer Animal Nutrition, announce it has acquired Agro Biosciences (Wauwatosa, WI; no SBIR). Agro BioSciences is a leading microbial biotechnology company with an innovative platform to provide novel, science-based products for animal and agricultural production. [joint companies press release, May 1, 17] for $75 million plus a contingent payment of up to an additional $25 million based on business performance. Agro BioSciences, Inc. is an innovator and leader in developing custom probiotic products for poultry, cattle and swine. [Church press release, May 4, 17]
Stratatech (Madison, WI; $14M SBIR), which is developing stem cell-based human tissue for treating burn wounds, said the first patient has been enrolled in a Phase 2 clinical study of its core skin replacement product, StrataGraft. was acquired by U.K.-based Mallinckrodt (NYSE: MNK) last August for $76 million in cash, though the company could be on the hook for another $121 million in milestone payments. [Jeff Buchanan, xconomy.com, May 10, 17]
Guardant Health (Redwood City, CA; no SBIR) that sells blood tests to track and, potentially, detect cancer, is announcing this morning that it has raised $360 million from investors, with the goal of deploying its test in 1 million people over the next five years. That brings the total Guardant has raised to $550 million. ... Guardant has a new competition: A Silicon Valley company called Grail, spun out of DNA sequencing giant Illumina. Earlier this year, Grail announced that it had raised $900 million from the likes of Bristol-Myers Squibb and Johnson & Johnson. [Matthew Herper, Forbes, May 11, 17]
Cytori Therapeutics (San Diego, CA; $250K SBIR) is re-starting a San Antonio manufacturing facility it gained through its acquisition of Azaya Therapeutics (no SBIR) , a maker of nanoparticle-encapsulated generic drugs. The San Diego company plans to find a European distributor for a drug the San Antonio facility makes called ATI-0918, which is a formulation of generic chemotherapy drug liposomal doxorubicin. [Angela Shah, xconomy.com, May 9, 17]
Lantern Pharma (Dallas, TX; no SBIR, founded 2012) closed its Series A equity financing of $3.7 million ... late-stage clinical drugs are “rescued and repurposed” by Lantern through molecular profiling to identify patients who will respond favorably. [Olivia Nguyen, healthcare.dmagazine.com, May 4, 17]
bioAffinity Technologies (San Antonio, TX;no SBIR) announced that the European Patent Office (EPO) has issued a patent that protects the Company’s proprietary CyPath® technology for the early detection of lung cancer through 2030. [company press release, May 3, 17]
Agri-Star (Mexico), a company of Albaugh, LLC group and a leading distributor of crop protection products in Mexico and Marrone Bio Innovations (Davis, CA), a leading provider of effective and environmentally responsible pest management and plant health products, announced today the companies have signed an exclusive agreement to distribute and market two MBI bioinsecticides, GRANDEVO® and VENERATE® in Mexico. .... also Marrone and Jet Harvest Solutions, a leading developer of agricultural products to control disease and post harvest decay, announced that the companies have entered into a master distribution agreement to market Jet Harvest’s Jet-Ag. [Marrone press releases, May 11, 17] , earlier announced public stock offering to raise $8M [Apr 25, 17]
Juicero made the perfect punchline: a celebrated startup that had received a fawning profile from the New York Times and $120m in funding from blue-chip VCs ... was selling an expensive [$400 a copy] way to automate something you could do faster for free. ... another example of how profoundly anti-innovation America has become .... That’s because real innovation is very expensive to produce: it involves pouring extravagant sums of money into research projects that may fail, or at the very least may never yield a commercially viable product. In other words, it requires a lot of risk – something that, myth-making aside, capitalist firms have little appetite for. ... The economy becomes a mechanism for making the rich richer, and the money that might be used to finance the next internet is allocated to sports cars and superyachts. [Ben Tarnoff, The Guardian (UK), May 11, 17]
America has the only healthcare system in the world designed to avoid sick people. Private for-profit health insurers do whatever they can to insure groups of healthy people because that’s where the profits are. They also make every effort to avoid sick people, because that’s where the costs are. [Robert Reich, robertreich.org, May 7, 17]
“Government bureaucrats can be very dangerous when they have power” to make decisions on people’s health, [Congressman] MacArthur said, prompting one woman to tell the congressman she would prefer that scenario than “someone in an office” of an insurance company making the same decisions. [Adam Gabbatt and Lauren Gambino, The Guardian (UK), May 11, 17] Republicans face older and sicker constituents in stormy townhalls. The party driven by tax cuts for the wealthy face the voters who survive with government help. The wealthy do not show up to defend their demand for government help with their tax bills.
Neuralstem up 36% [May 10,17]
Array Biopharma up 20% [May 10,17]
IntraCellular Therapies up 14% [May 10,17]
Cleveland Biolabs up 12% [May 10,17]
Aqua Metals down 26% [May 10,17]
ACADIA Pharma down 10% [May 10,17]
Medical-device maker Conventus Orthopaedics (Maple Grove. MN; no SBIR, founded 2008), announced that it had locked down $20 million in equity financing. With the latest funding round, the early-stage medtech company has attracted nearly $95 million from investors over the last four years. ... Its flagship product, The Conventus Cage, is made of nitinol, a memory shape alloy, and can be inserted into a fractured bone. From inside the bone, the Cage expands, creating a “rigid internal scaffold” that prevents further collapse of the fractured bone. [Sam Schaust, Twin Cities Business, May 9, 17]
Cree announces it is forming a joint venture with San’an Optoelectronics Co., Ltd. (SHA: 600703) to produce and deliver to market high-performing, mid-power lighting class LED packaged products in an exclusive arrangement to serve the expanding markets of North and South America, Europe and Japan, and serve China and the rest of the world on a non-exclusive basis. [company press release, Apr 25, 17]
Dundee Venture Capital (Omaha, NE) raises $31M ... open to investing in technology companies with high growth potential across numerous industries, but they feel that their most successful partnerships occur when they invest in companies within the industries their partners know well. [Christine McGuigan, Silicon Prairie News, May 8, 17]
Portola Pharma up 13% [May 9,17]
AMRI up 12% [May 9, 17]
KVH Industries (Middletown,RI: $5.7M SBIR) up 12% [May 9,17] despite greater loss, [CEO] Martin Kits van Heyningen said, "We are particularly pleased with the growth in our Airtime service revenues and margins, and with our strong cash flow which allowed us to reduce our net debt by over $3.0 million at the end of the quarter. [company press release, May 9, 17]
Neuralstem down 28% [May 9,17]
Kopin down 10% [May 9, 17]
Edico Genome
(San Diego, CA;
SBIR), which makes a
fast processing
platform for next generation gene sequencing, said Tuesday that it has
raised $22 million in a second round of venture capital fundingled by Dell
Technologies
Capital.
Though it has been
quietly investing
in startups for a couple of years, Dell Technologies Capital revealed
its $100 million start-up fund on Monday after previously operating in
stealth mode. [Mike Freeman, San Diego Union Tribune, May
9, 17]
Dell Ventures, in stealth until today, has been steadily investing at a rate of about $100 million per year. The group certainly knows what the market is willing to buy. It’s seen nearly 37 percent of its 70-plus investments exit, albeit with mixed results. ... Dell’s exits alone have gone on to collectively raise $1.3 billion. The group brings the traditional benefits of a corporate venture arm to its startup portfolio — access to data, strategic sales channels and engineering and research contacts. [John Mannes, techcrunch.com, May 9, 17]
GV (formerly Google Ventures) is leading a $10 million investment in Abundant Robotics (Hayward, CA; no SBIR), a company building apple-picking robots that could eventually be adapted to harvest other fruits. [Lora Kolodny, techcrunch.com, May 3, 17]
there are already lots of proven use-cases where AI is being used to augment the medical profession. One proven area is in medical imaging where AI and computer vision is helping with medical scan and imaging analysis to help support radiologists and other clinicians. One startup operating in this space is AIdoc Medical (Israel). ... solution is an AI system that can look at an [medical scan] anatomical area and detect high-level visual abnormalities, based on what the radiologist would like to see. [Steve O'Hear, techcrunch.com, Apr 26, 17]
The American economy is poised to embark on an innovation boom of historic proportions that will undermine incumbent players, transform everyday life, and make some alert investors very rich. .... The combination of advances in platforms and intolerable pain is about to result in an explosion in entirely new applications that are inexpensive to operate, are far less likely to fail, are far more secure, and easily accommodate unimagined advances in ease of use and effective output. This scenario will be seen in sector after sector. [John Michaelson, CEO of Michaelson Capital Partners, Wall Street Journal, May 10, 17]
I believe the accelerations set loose by Silicon Valley in technology and digital globalization have created a world where every decent job demands more skill and, now, lifelong learning. More people can’t keep up, and clearly some have reached for leaders who promise to stop the wind. [Tom Friedman, New York Times, May 10, 17]
Richard Milhous Trump fired his chief investigator, which ignited a firestorm over how the decision would impact the agency’s investigation into possible collusion between the Trump campaign and Russia. [Wall Street Journal, May 10, 17] Anyone who was an adult in the early 1970s would remember Nixon's travails with a chief investigator getting too close to the inconvenient truth. The President has fast power, but Congress has the slow ultimate power. An ugly and perilous power struggle could result between autocratic business and representative democracy in a politically polarized nation.
CombiMatrix up 19% [May 8, 17]
Alder Bio (Bothell, WA; one SBIR) down 10% [May 8,17]
Immunogen down 10% [May 8,17]
PTC Therapeutics down 12% [May 8, 17] said that it would receive a net price of $35,000 annually per patient for Emflaza, the muscular dystrophy drug it acquired from Marathon Pharmaceuticals LLC last month. ... Marathon had ignited a backlash from patient advocates and politicians in February when it announced a wholesale list price of $89,000 annually for Emflaza after it was approved for sale by [FDA]. The price was some 70 times more than some U.S. patients had been paying to import Emflaza from the U.K. [Joseph Walker, Wall Strreet Journal, May 8, 17]
A bid by a group of investors to transform a stalled cancer drug into an eye disease treatment has paid off. Horizon Pharma (Ireland) [down 35% May 8, 17] acquired River Vision Development (New York, NY; SBIR) formed to develop a therapy for an eye condition called Graves’ ophthalmopathy. .... paying $145 million in cash up front for River Vision and its drug teprotumumab, an antibody in mid-stage testing for GO. [Ben Fidler, xconomy.com, May 8, 17]
startup ID Genomics (Seattle, WA; no SBIR) has developed technology to identify bacteria in 30 minutes, giving doctors all the information they need to prescribe the best treatment. The goal is to identify the bacteria’s exact “fingerprint” while the patient is still in the clinic, so doctors can choose a narrowly targeted antibiotic. ... For several years, Sokurenko and the 10-person ID Genomics team has been creating a database of different strains of E. coli bacteria, which causes the majority of urinary-tract infections. Each strain has distinct characteristics. “It’s sort of like a bar code,” said Sokurenko [Rachel Lerman, Seattle Times, Apr 24, 17]
Scientists at UC San Diego and Sapphire Energy (San Diego, CA; $200K SBIR) say they have successfully completed the first EPA-approved outdoor field trial of genetically engineered algae. Cultivating the algae outdoors didn’t harm nearby populations of wild algae, the scientists say in a study published Thursday [Bradley Fikes, San Diego Union Tribune, May 8, 17]
Cellular analysis startup Celcuity LLC (Plymouth, MN; no SBIR) received a $5.75 million cash infusion during its latest funding round. ... Its flagship product, CELx, is a diagnostic test that analyzes live tissue and can determine a more accurate diagnosis for cancer patients, particularly those with breast cancer. [Sam Schaust, Twin Cities Business, May 3 , 17]
United Therapeutics
(Silver
Spring, MD; no SBIR) has
ambitions
to build an unlimited supply of certain transplantable
organs.
... said the company's new multiyear collaboration —
specifically
with United Therapeutics' transplantation-focused subsidiary, Lung
Biotechnology
PBC — will use patient-specific
biological material, including re-differentiated stem cells, to create
materials for the transplants. The project will be based out of 3D Systems (San
Diego, CA; no SBIR) new
bioprinting lab. ... United
Therapeutics additionally invested $100 million in two rounds, in 2014
and 2016, in Synthetic
Genomics
(La Jolla, CA), a
company started by
scientist J. Craig Venter, to further its own research and development
in its North Carolina facility. The local company also invested $41.8
million in TransMedics
(Andover, MA; no SBIR) that
develops
ex vivo perfusion systems for donor lungs, hearts and kidneys.
[Tina Reed, Washington Business Journal, May 2, 17]
The University Early Stage Proof of Concept Fund, also known as the Advance grant program, will help move research projects and technologies developed at Michigan universities from the discovery phase to commercialization. The total amount in the new fund is $1 million, to be doled out in increments of up to $40,000 to technology transfer offices in order to advance research through market analyses, proof-of-concept validation, technical feasibility demonstrations, and developing prototypes ahead of implementation and testing. The fund also requires universities to match each grant dollar for dollar. [xconomy.com, May 8, 17]
"We were young and ignorant then; Now we're old and ignorant." -- Charlie Munger, Warren Buffet's 93-year-old alter-ego. Charlie's other gems from the annual meeting attended by 40,000.
Energy Focus up 25% [May 5, 17] (Solon OH; $3M SBIR, 130 employees) [CEO] Tewksbury, commented, "As expected, we continued to experience headwinds due to excess inventory in the channel, lackluster Navy demand and delays in commercial projects, but we are beginning to see signs that our restructuring efforts and five-point strategy will return the Company to profitable growth. [company press release, May 4, 17]
Universal Display up 24% [May 5, 17]
Applied Optoelectronics up 20% [May 5, 17]
Immunomedics up 18% [May 5, 17]
Fluidigm up 18% [May 5, 17]
CombiMatrix up 11% [May 5, 17]
Exact Sciences up 11% [May 5, 17]
American Superconductor down 18% [May 5, 17] announced that it has priced its underwritten public offering at $4.00 per share [for] gross proceeds of $16M [company press release, May 5, 17]
Immersion down 10% [May 5, 17]
Seattle Genetics announced that it has agreed to terminate its license agreement with Immunomedics for sacituzumab govitecan (IMMU-132) and settle the related litigation. The license agreement had not yet closed due to legal action brought by an Immunomedics stockholder challenging the transaction. The termination and settlement remain subject to court approval. [Seattle Genetics press release, May 5, 17] Meanwhile, Immunomedics is charting its own path forward, raising $125 million in a stock sale to private investors to support development of the drug that SeaGen had hoped to bring to market. [Frank Vinluan, xconomy.com, May 5, 17]
Intra-Cellular Therapies said the FDA has raised questions relating to certain findings observed in nonclinical animal toxicology studies of lumateperone and has requested additional information to confirm that the nonclinical findings are not indicative of a safety risk associated with long term exposure in humans. [company press release, May 1, 17]
Ovid Therapeutics (New York, NY; no SBIR) raised $75 million in an IPO, continuing a recent flurry of biotech offerings—among them BioHaven Pharmaceuticals (New Haven, CT; no SBIR) and UroGene Pharma (New York, NY; no SBIR) —that have all met or exceeded their share price projections. [Ben Fidler, xconomy.com, May 5, 17]
Magenta Therapeutics (Cambridge, MA; no SBIR) a biotechnology company developing therapies to improve and expand the use of curative stem cell transplantation for more patients, today announced rapid progress in advancing the company’s strategic vision, including the completion of a $50 million Series B financing; in-licensing a clinical-stage program from Novartis to support the use of stem cell transplantation in a variety of disease settings; and a strategic partnership with Be The Match BioTherapiesSM, an organization offering solutions for delivering autologous and allogeneic cellular therapies. [company press release, May 2, 17]
Zymeworks (Canada) announced the closing of its[IPO] for a total of U.S.$58,5M in aggregate gross proceeds. [company press release, May 3, 17]
ChromaCode (Carlsbad, CA; no SBIR) a molecular diagnostics company, announced it has raised $12 million in Series B funding. ... will be used to fuel development and establish the commercial infrastructure for ChromaCode's High-Definition Polymerase Chain Reaction technology (HDPCR™). [company press release, Apr 27, 17]
Karyopharm Therapeutics (Newton, MA; no SBIR) announced the pricing of a registered underwritten public offering [with] gross proceeds expected to be $40M. [company press release, Apr 28, 17]
Karyopharm Therapeutics and Anivive Therapeutics (Orange, CA, no SBIR), focused on innovations in the veterinary drug and bioinformatics space, announced their entry into a licensing agreement whereby Anivive licensed from Karyopharm exclusive worldwide rights to research, develop and commercialize verdinexor (KPT-335) for the treatment of cancer in companion animals. [company press release, May 3, 17]
A compound that Karyopharm Therapeutics (Newton, MA; no SBIR) tested as a potential treatment for cancer and viruses was licensed to which plans to bring the drug to market to treat dogs diagnosed with lymphoma. [Ben Fidler, xconomy.com, May 5, 17]
DrugCendR (La Jolla, CA; no SBIR) developing tumor-penetrating peptides that enhance delivery of anticancer drugs announced it has entered into a collaboration with Xiamen Tobefar Technology Co. Ltd (China), partially owned by Peking University and Beijing Institute of Collaborative Innovation (BICI). [company press release, May 3, 17]
Epic Sciences (San Diego, CA; no SBIR) announced that the company has completed a $40 million Series D financing .... is developing a portfolio of blood-based tests that predict drug response in cancer and recently partnered with Genomic Health to commercialize the OncotypeDx® AR-V7 Nucleus Detect™ test to leverage Genomic Health’s world-class commercial channel and enterprise systems. [company press release, Apr 28, 17]
Vanda Pharmaceuticals (Washington, DC; no SBIR) has expanded its portfolio to include research and development into treatments for cystic fibrosis and blood cancer. During a first-quarter earnings call this week, CEO Mihael Polymeropoulos said Vanda is on track to file an investigational new drug application for trichostatin A to the Food and Drug Administration in mid-2017 for clinical study of hematologic malignancies. [Washington Business Journal, May 5, 17]
Wuxi NextCODE—the Shanghai company formed out of Wuxi Pharmatech’s acquisition of Cambridge, MA, and Iceland-based genomic data startup NextCODE Health two years ago—closed a $75 million Series B round led by Temasek and Yunfeng Capital. [Ben Fidler, xconomy.com, May 5, 17]
Engineers at the AMRC (University of Sheffield Advanced Manufacturing Research Centre, Sheffield (England)) have developed a hybrid 3D printing process that allows electrical, optical and structural elements to be introduced throughout an additively manufactured component during the build process ... With the project currently at patent-pending status, [inventor of the technique, Mark] Cocking was tight-lipped on specific technical details but he did confirm that the process – which is fully automated – is able to embed strands – and potentially even tubes – of different materials groups such as copper, fibre optic, steel, and nitinol during the 3D printing process. He added that the technique also allows unbroken connectivity through X, Y and Z axis directions and that single or multiple strands can be embedded at a rate that does not effect the original build time of the component. [The Engineer, May 4, 17]
As [Drezner] tells it, three large-scale forces have remade the marketplace of ideas. The erosion of trust in prestigious institutions, the polarization of American politics, and the dramatic growth in economic inequality has made wealthy individuals and corporations into the primary buyers, dominating the market. [Noah Millman reviewing Daniel Drezner's The Ideas Industry, New York Times, May 6, 17]
“The causes of the current slowdown can be summed up as the Three Ds: depopulation, deleveraging and deglobalization. Between the end of World War II and the financial crisis of 2008, the global economy was supercharged by explosive population growth, a debt boom that fueled investment and boosted productivity, and an astonishing increase in cross-border flows of goods, money and people. Today, all three trends have begun to sharply decelerate: families are having fewer children . . . , banks are not expanding their lending [as before] . . . , and countries are engaging in less cross-border trade.” [Robert Samuelson quoting Ruchir Sharma, a top investment strategist at Morgan Stanley, Washington Post, May 7, 17] Beware of politicians' promises of big growth from their pet-rock, applause-tested ideas.
Make science fit the answers. The Environmental Protection Agency has dismissed at least five members of a major scientific review board, the latest signal of what critics call a campaign by the Trump administration to shrink the agency’s regulatory reach by reducing the role of academic research. A spokesman for the E.P.A. administrator, Scott Pruitt, said he would consider replacing the academic scientists with representatives from industries whose pollution the agency is supposed to regulate, as part of the wide net it plans to cast. [Coral Davenport, New York Times, May 7, 17]
It takes little courage to aid those who are already powerful, already comfortable, already influential, but it takes great courage to champion the vulnerable and the sick and the infirm. [Barrack Obama, May 7, 17]
More campaign inanities. President Trump declared that “everybody” on the world stage has better health care than the United States, but suggested that the GOP’s health care plan will change that. .... “But our healthcare will soon be great.” ..... it’s somewhat ironic that the countries [actually] outranking the U.S. in general reports on this topic, such as the Commonwealth Fund, tend to provide health care for their citizens regardless of their wealth or economic status — Canada and Norway, for instance. [Michael Walsh, Yahoo News, May 5, 17] Advertisers would be called out on such claims; politicians can be called out only at the next election. And this politician was actually rewarded for endless inanities in the last election. But Trump had told us his design: In “The Art of the Deal,” Trump said that playing to people’s fantasies and promising the greatest product was “an innocent form of exaggeration.” [Maureen Dowd, New York Times, May 6, 17]
Paratek Pharma (Boston, MA; $3.8M SBIR) up 15% [May 4, 17] Reported positive top-line efficacy and safety data in the OPTIC study, a Phase 3 registration study of omadacycline in CABP [company press release, May 3, 17]
Emcore up 14% [May 4, 17] excellent growth in revenue and non-GAAP net income [company press release, May 4, 17]
Progenics Pharma down 13% [May 4, 17] reported wider loss [company press release, May 4, 17]
BioCryst Pharma down 11% [May 4, 17]
US House passed tax-cut bill promoted as healthcare improvement. After all, Republicans were born to cut taxes. Trump approves of cutting health insurance from his loyal under-employed Rust Belt voters. Fortunately for him, they probably do not yet recognize their loss. Bottom-line message: you're on your own. The rich and healthy benefit, but poor and disabled people who use Medicaid could lose out. [MARGOT SANGER-KATZ, New York Times, May 5, 17] Meanwhile, Senate Republicans have been working for weeks writing their own version, [Wall Street Journal, May 4, 17] In the Senate, where gerrymandered districts for safe seats does not apply, centrist approaches have more appeal. Who's a big winner so far? The rich and smiling President who gets huge tax cuts and does not need health insurance.
Myriad Genetics up 20% [May 3, 17] "We were very encouraged to see sequential growth in hereditary cancer testing volumes for the second consecutive quarter," said [CEO] Mark C. Capone [company press release, May 2, 17]
Neurotrope up 13% [May 3, 17]
First Solar up 12% [May 3, 17]
"It's not a good time to be a scientist ," said Dr Avissar, dean of UMiami School of Marine Science at the the opening of the new $300M science museum in Miami. in a state where the governor forbids state employes from even saying "climate change". [New York Times, May 3, 17]
ChromaDex (Irvine, CA; one SBIR) up 19% [May 2, 17]
Neurotrope up 17% [May 2, 17]
II-VI down 16% [May 2, 17]
Array BioPharma down 16% [May 2, 17]
Chimerix down 11% [May 2, 17]
Intra-Cellular Therapies down 10% [May 2, 17]
iRobot announced new features intended to make its Roomba vacuums “smarter,” continuing the company’s sharper focus on consumer robotics and its goal of enabling the connected home. .... is adding Wi-Fi connectivity to its cheaper Roomba 600 and Roomba 800 series of autonomous vacuums, a capability that was previously only available in its most expensive line of vacuums, the Roomba 900 Series [Jeff Engel, xconomy.com, May 2, 17]
Magenta Therapeutics (Cambridge, MA; no SBIR) said it has doubled its money with a $50 million Series B round. .... spun out of Harvard University last year with nearly $50 million in launch money to develop improved bone marrow transplants. ... has also licensed a drug from Novartis that it says could help boost the number of healthy stem cells that are delivered into a patient’s body, a key procedure in a transplant. [Alex Lash, xconomy.com, May 2, 17]
news and views about government programs, politics, attitudes ...1996-1997; 1998; 1999; Y2K; 2001 , 2002-2003 ; 2004-5; 2006; 2007-08 2009-2010; 2011-2012; 2013-14 ; 2015; 2016-17
BMDO/ MDA including SBIR the doings of star wars
Miscellaneous Stories 1996-1997; 1998-1999; 2000-2001; 2002-2003 ; 2004-5 ; 2006; 2007 2009-2010 ; 2011-2012; 2013-2014; 2015; 2016-17
IPO and Venture Markets 1996-1998 .... 1999-2005 ... 2006-present
Quotes steal them if you like
Note: in these old stories, many links are dead, obsolete, or missing
Stories about companies; 1-Al .. Am-Az .. B .. C ... D-E .. F .. G-H .. I-J .. K-L .. M ... N-O ... P ... Q-R .. S1-Se .. ... Sf-Sz .. T-U .... V-Z
10X Genomics ..... 1366
Technologies ... 1st Detect ...
21-Century Silicon ... 21st Century
Systems .... 23andMe ... 24M Technologies
... 30
Second Software ... 360fly ..... 3Bar Biologics .... 3C Semiconductor
... 3D Glass Solutions ..... 3D
Robotics .... 3D Systems
..... 3D Technology
Laboratories
.... 3F ... 3PrimiR ... 3Scan ..... 3-V
Biosciences
.... 3VR ... 410 Medical Innovation .... 454 Life Sciences .... 4s3
Bioscience ... 5D Robotics
..... 7AC
Technologies ... 908Devices ... 9Mile Labs
A10 Networks ... A123Systems ... A&G
Pharmaceutical ... Aastrom
Bioscience
.. Abacus Technology ... ... Abaxis .... Abcombi Sciences
.....
Abeona Therapeutics
..... AbGenomicsInternational
... Abiomed ... Ablexis
...... ABL
Technologies .... Absorbent
Materials ... AbVitro ... Acadia Pharma ... Acambis
.. Accel Diagnostics ..... Acceleron Pharma
... Accelrys
... Accentia
BioPharmaceuticals ... Accera .... Access Pharmaceuticals
...
Access
Scientific .... Accion Systems ..... Accumetrics
... AccuraGen ..... Accurate
Automation
.. Accuray ... Accuri Cytometers
... Acelerox ....
Acelity .... AcelRx
Pharmaceuticals ...
Acera Surgical ....
Acetylon
Pharmaceuticals ... Achaogen ... Achates
Power .....
Achillion
Pharmaceuticals ... ACIST Medical Systems .... Acorda
Therapeutics
... Acorn
Cardiovascular ... Acquia .... AcroMetrix
... AcryMed ...
ActaCell ... Actasys .... ACT Biotech ... Active
Power ...
ActivBiotics
... ActivMedia Robotics .... Acton Pharmaceuticals
...
Actuality... Acucela ... AcuFocus ....
Aculight
...
Acumentrics ... Acutus Medical .... Adamas Pharmaceuticals ......
Adamis Pharmaceuticals
... Adapteva .... Adaptimmune Therapeutics .... Adaptive
Biotechnologies ..... Adaptive
Computing
... Adaptive TCR ... Adarza BioSystems .....
Addiction
Therapeutix
...
Addrenex Pharmaceuticals ... Adelor ... Adenosine
Therapeutics
... Adesto Technologies .... Adeza Technologies ... Adherex
Technologies ... Adhesys Medical .... Adicet Bio .... AdiMab
... ADispell ... Adlyfe .... Admittance
Technologies
.... Admune Therapeutics ..... Adnexus
Therapeutics ... Adrenergics .... Advanced
BioHealing ... ADS Biotechnology ... Aduro BioTech
.... Advanced Animal Diagnostics .... Advanced Biologics ..... Advanced
Bionics
... Advanced Cell Diagnostics ... Advanced Cell
Technology (now sub to Bio-Techne) ... Advanced Ceramics
.... Advanced
Circulatory .....
Advanced Countermeasures
Systems ... Advanced Diamond
Technologies .... Advanced Electron Beams ...
Advanced Fuel
Research ...Advanced Life Sciences ... Advanced Lighting
Technologies ... Advanced Liquid Logic
...
Advanced Magnetics ... Advanced Photonix ....
Advanced
Programming Concepts ... Advanced Receiver
Technologies .... Advanced Scientific Concepts ..... Advanced Targeting
Systems
.... Advanced
Technology
Materials.(ATMI) ... Advanced Uro-Solutions ..... AdvanDx ...
Advantic ..... Advaxis ..... Adventrx
... Adverum Biotechnologies ..... Advion BioSciences
...
Adynxx .... .Aegea
Medical ... Aegerion Pharmaceuticals .... Aeglea
BioTherapeutics
Holdings ..... Aerial BioPharma .... Aerie
Pharmaceuticals
... Aerin Medical ..... Aerius Photonics
... Aerodyne Research ... Aero Farms System
...
AeroVironment ... Aerpio Therapeutics .... AesRX
...
AETC ... Aethlon Medical
... Aethon .... Affectiva .... Afferent
Pharmaceuticals ..... Affigen .... Affinimark
Technologies
... Affinity BioReagents ... Affinium
Pharmaceuticals ..... Affinivax .... Affomix ....
Affymax ....Affymetrix ... aFraxis ... AgBiome ..... AgeneBio
....
Agennix ... Agenovir ..... Agenus .... Agere
Pharmaceuticals ..... Agile
Materials
... Agile
Planet ... AgileSwitch .... Agile Therapeutics ....
Agiltron...Agilvax .... Agilyx ....
Aagios
Pharmaceuticals... AgraQuest .... Agritope... Agrivida
...Aguila
Technologies.....Ahura Scientific.... Aiko Biotechnology
... Aileron Therapeutics .... Aimmune Therapeutics
(formerly
Allergen Research) ..... airtricity... Airware .... Airxpanders ....
Airway Therapeutics .... ait laboratories... Akamai
Physics
Akarna
Therapeutics
..... Akashi Therapeutics ..... Akebia ....
akermin ...
Akita Innovations ... Akron Polymer Systems ..... Akron Surface
Technologies ..... Akros Medical ....
Alabama
Cryogenics ... Alafair Biosciences .... Albany Molecular
(AMRI) ...A?
nanotech .... Alcon .... Alcresta
.... Aldagen
... Aldatu Biosciences ..... Aldea
Pharmaceuticals
... .
Alder biopharma Aldevon ..... Aldeyra Therapeutics (formerly
Aldexa Therapeutics) .... Alector .... Alexar Therapeutics .....
Alexion
... ....Alexza ....
Alfalight.... Algaeventure Systems ... Algenetix .... Algeternal
.... Algorithmia ..... Alien Technology
.... Alimera sciences.... Alios BioPharma ....Aliva
biopharmaceuticals ..... Alivio Therapeutics .....
Alkermes...
Alkeus Pharmaceuticals ...
Allakos ... Allcast ....
Allegro Diagnostics ....
Allegro
microsystems ... Allena Pharmaceuticals .... Allergy Amulet
.....
Allerquest
.... Allied BioScience ..... Allied Minds .... Alliqua .... Allos
Alloy Polymers .... Alloy
Surfaces .....
Allurion Technologies ... Allylix ... Alnara Pharmaceutical
...
Alnylam... Alper Biotech ... Alphabet Energy .... AlphaCore Pharma ...
Alphamed.... Alphatec
Holdings .....
Alphavax ... Alpine Biosciences .... Alpine Data
Labs .... Alpine Immune Sciences ..... Alseres ....
Algeternal
.... Alta Devices ... AltAir Fuels ... Altair
Therapeutics
... Altamira Technologies .... AltaRock
... AltheaDX .... Althea
Technologies ... Altimmune ..... Altor ...
Altra ...
Altura Medical ... Altus Pharmaceuticals ...
ALung
Technologies
... Alvine Pharmaceuticals .... AMAG
Pharmaceuticals
... Amaranth Medical .... Ambarella ..... Amberwave ... Ambiq
Micro ....
Ambit
Biosciences .... AMBP
Technology ... Ambri .... Ambrx ...
Ambry .... Amendia .... American
Gene Technologies International .... American Lithium Energy ....
American Medical Systems ....
American Science and Engineering
... America Stem Cell, now Targagyme .... American
Superconductor
... American XTAL .. Ames
Technology ... Amgen ... Amionx ..... Amnis ...
AMO
Pharma .....
Ampla
Pharmaceuticals ... Amplimmune .... Amplyx Pharmaceuticals
.....
Amprius .... ARMO
BioSciences
.... Amylin
Pharmaceuticals
... Amylyx ..... Amyris
Biotechnologies ... Anacor Pharmaceuticals ...
Anadys
Pharmaceuticals ... Anakim Biologics ....
Analog Computing
Solutions .... AnaptysBio
... Anavex Life Sciences .... Anchor Therapeutics ...
Ancora Pharmaceuticals
... AnDAPT ..... Anexon .... Anew Optics ... Angeion ...
AngioDynamics
... Angiologix ... Angstrom Medica .... Angstron
Materials
... Animalgesic Labs .... ANI Pharmaceuticals ...
Animetrics .... Anivax .... Annexon Bioscience ..... ANP Technologies
..... Ansoft
... Ansun Biopharma (formerly NexBio) .... Antegrin
Therapeutics
..... Anthera
Pharmaceuticals ....
Antigenics ... Anue Systems ... Anulex Technologies
... Anybots ... AOptix Technologies
... Aortica ..... APA
Optics (Enterprises) ... Apexigen ... Aperion
Biologics
.... Aphios
...
Apieron ... Apnex Medical ... ApniCure .....
ApoCell ....
ApoGen Biotechnologies .... Apollo
Diamond
... Apollo Endosurgery ... Apoplogic
Pharmaceuticals
... Applied Biomolecular Technologies .... Applied Biosystems
.... Applied Genetic Technology ...
Applied Nanotech ....
Applied
NanoWorks ... Applied Optimization ..... Applied
Optoelectronics ... Applied Physical Electronics ...
Applied Physical Sciences ... Applied Proteomics ..... Applied Quantum
Technology
.... Applied Research Associates
... Applied
Science and Technology ... Applied Signal
Technology
... AppThwack .... Aprecia Pharmaceuticals ....
Apricus
Biosciences
... APS BioGroup .... Apse .... Aptalis Pharma .... Aptevo
Therapeutics .....
Aptima ... AptamiR
Therapeutics .... Aptus
Endosystems ... Aquaback Technologies ...
Aqua Bounty
... Aquacue .... Aqua Metals .... AquaMost ... Aquarius
Technologies ...
AqueSys
... Aquion .... AragonPharmaceuticals ... Aratana
Therapeutics ..... Arbor
Pharmaceuticals ...
Arbovax
... Arbutus BioPharma (formerly OnCore) ..... Arca Biopharma ....
Arcadia Biosciences .....
Arcantatura...
Archemix
... Arch Innotek ..... Arch Therapeutics
... Arctic Sand Technologies .... Arcturus Therapeutics ....
Arcus Biosciences ..... Ardea Biosciences ...
Ardelyx .... Ardian .... Arena Pharmaceuticals
... Argentum ..... Arginetix
... Argo AI ..... ArgonST ... Argos Therapeutics ... Aria CV
...
Ariad
Pharmaceuticals .. Ariosa Diagnostics ..... Arista MD ....
Arista
Networks ....
Arkansas Power Electronics ..... Armadillo Aerospace
... Armetheon .... ARMO BioSciences .... Armorworks
... Arpeggi .... ArQule ... Array
... Arresto
Biosciences .... Arrien Pharmaceuticals ... Arrivo
BioVentures ..... Arrowhead
Research .... Arsanis ... Arsenal Medical
....
Arstasis ... Arteriocyte ... Arterys .....
ArthroCare
...
Arthrosurface ... Artisan Pharma ... Arvegenix ..... Arvinas
....
Arxan
Technologies .... Aryx
Therapeutics ..... Aryx
... Arzeda
... Asana Medical .... Asante Solutions ..... Ascelegen
Therapeutics .... Ascension
Orthopedics ... Ascent
Solar Technologies ....
Ascent
Therapeutics .... AsclepiX Therapeutics .... Aseptia .... Ash
Access Technology ....
AstroWatt .... Aspen Aerogels .... AspenBio
Pharma .... Aspen Products Group ....
Aspen
Technology
... Aspyrian Therapeutics .... Assurex Health ..... Astex
Therapeutics ...
Asthmapolis
.... Astralux
... Astrobotic Technology ....
Astronautics Corp. of
America ... AstroPower... AstroTerra ..
Astrum Solar ... Astute
Medical ....
Astute Medicales ... Asuragen
... Atara Biotherapeutics ..... Ataxion .... Athenex (formerly
Kinex) ..... Athenix
... Athens Research ..... AtheroGenics ... AtheroMed ....
Athersys .... ATI Industrial
Automation
... Atlantia ... Atmocean .....
Atmospheric Glow
Technologies ...
Atomate ... Atomic Medical Innovations .....
Atomometrics
... Atoptix .... Atossa
Genetics
... Atreaon ....
AtriCure ... Atrium
Medical ... ATRP Solutions ... aTyr Pharma .....
Audentes
Therapeutics ..... Audience
... Augmenix
.... AUM
Cardiovascular ... Aura Biosciences ....
Auris Medical .... Auris Surgical Robotics ..... Aurora
Algae ... Aurora Flight
Sciences ....
Aurora
Imaging Technology ...
Aurora Spectral Technologies
... Auspex
Pharmaceuticals ... Ausra ... Auterra
.... AuthenTec
....
Automated Dynamics ...
Automated
Medical Instruments .... Autonet ... Aushon
Biosystems
... AutoGenomics .... Autonomic Materials
.... Autonomic Technologies ..... Autonomous Technologies
....
Auxilium
Pharmaceuticals ... Avalanche
Biotechnologies ....
Avanir Pharmaceuticals
... Avant Immunotherapeutics ... Avanti Metal ...
Avaxia
Biologics ... Avedro ... Avelas Biosciences ....
Aveo
Pharmaceuticals
... AveXis .... Aviation Resources Delaware .... AVI
BioPharma ... Avici Systems ... AvidBiotics
.....Avidity
Biosciences .... Avid
Radiopharmaceuticals
... Avila Therapeutics ... Avinger ....
... Aviragen Therapeutics (formerly Biota
Pharmaceuticals)
..... Aviron ..... Avita Medical Americas ..... Avitude .... Avrobio
..... AVT Simulation .... Aware ... Axcella Health (was Pronutria)
.....
Axelo .... Axerion Therapeutics
... Axial
Biotech .... Axial Biotherapeutics ..... Axion BioSystems
.....
Axion Power
... Axis Clinicals .... Axis
Semiconductor
... Axium Nanofibers ...... Axogen .... Axonia
Medical ...
Axsun
Technologies ... Ayasdi ..... Azaya
Therapeutics ... Azelon Pharmaceutical ... Azimuth
....
Azure Biotech
Bacterial Robotics .... BacterioScan .... Baebies
..... Bagaveev
.... Ballard
Power ... Bamboo Therapeutics ..... Bandgap ... Banyan Biomarkers ...
Baryonyx .... Barrier
Therapeutics ... Basis Science .... Bastion
Technologies
.... Batu Biologics ..... Bauhaus Software ..... Baxano ...
Baxano Surgical .... Beacon Biomedical ..... Beacon Power ... Beat
Biotherapeutics .... Beeco
... Behavioral Recognition Systems .... Bellicum
Pharmaceuticals .... Belmont Instrument ....
Benchmark
Automation ... BeneChill
... Benefuel ... BeneVir Biopharm ....
Benson Hill
Biosystems ..... Benvenue
Medical .... Berg .... BerrieHill
Research
... BESS Technologies .... BetaBatt
...
BetaLED ....
LEDBG Medicine
... Bettergy .... Bexion Pharmaceuticals .... Bina
Technologies .... Bind
Bioscience ... Bind Therapeutics .... BinOptics ..... BiO2
Medical
... BiO2
Technologies
...
BioAmber ... BioAdvanTek ... BioAffinity
Technologies .....
Bioanalytical Systems
... BioBehavioral Diagnostics ... BioBridge
Global
..... BioCardia .....
BioCentra Molecular Innovations ..... Biocept
...
BioChemics ..... BioClin Therapeutics .... Bioconnect Systems ....
BioConsortia ..... BioCritica
...
BioCryst Pharmaceuticals
...
BioDelivery Sciences ... Biodesix .... BioDirection ..... BioE
...
BioFire .... BioFluidica ..... Biogenic
Reagents
.... BioGreenChoice ... Bioheart ...
Biohelix ... Bio-Imaging Technologies
...
Bioincept .... BioKier ..... Biolex Therapeutics
... BioLink Life
Sciences
... Biologics ... BioMagnetic Solutions ....
BioMarin
Pharmaceutical
... BioMarck
Pharmaceuticals .... bioMASON ..... Biomatrica ...
BioMedical
Enterprises
... Biomedical
Structures ...
BioMedix .... Biomeme .... Biometric
Signature
... BioMimetic Therapeutics
... BioMotiv .... BioNano
Genomics ... BioNanomatrix ... Bionostics
Holdings
... Bio-Path Holdings ..... Biophan Technologies
... Biophysical ... BioProcessors ...
Bioptigen
... Bioptix .... BiOptix Diagnostics ..... BioPulping
International
...
Biopure ... Biorasis ..... BioRelix ... BioResource
International
...
BioRestorative Therapies (formerly Stem Cell Assurance) ....
BioSante Pharmaceuticals ... BioScale
.... BioSense
Technologies ... BioSentinel
Pharmaceuticals
... BioSig Technologies ..... Biosortia Pharmaceuticals ....
BioSphere Medical
.... Biostage (formerly Harvard Apparatus
Regenerative
Technology) ..... BioStructures .... Biosurfaces .... Biosym
Technologies later Accelrys
....
BioSystem
...
Biota Pharmaceuticals .... Bio-Techne ..... BioTechnique ....
BioTechPlex .....
Biotectix
....
Biotel
.... BioTelemetry (formerly CardioNet) ..... BioTex
....
Biothera
... BioTheranostics ... Bio Time ...
Biotix
... Biotronic NeuroNetwork ..... Biotronik ....
BioTrove
... Bioventus ..... Biovest International .... BioVex
... Bird Rock Bio (formerly RuiYi) ..... Birich
Technologies .... Bitstream
... Black-I Robotics
... Black Sand ... BlackThorn
..... BladeLogic
... Blasch Precision Ceramics .... Blaze
Bioscience ... Blend
Therapeutics ....
BL Healthcare ... Block Engineering ...
Bloom Energy
... Bloo Solar ..... BluDiagnostics ..... Blue Belt
Technologies
...
Bluebird
bio ...
BluDiagnostics .... Bluefin Robotics ... Bluegrass
Proteins
.... Bluegrass
Vascular
Technologies .... Blueprint
Medicines ...
BlueRock Therapeutics ..... Blue
Sky Batteries ... Bluewater Bio International ... Bolt Threads ....
Boragen .... Boston Biochem
... Boston Biomedical ... Boston Dynamics
...
Boston Engineering ... Boston Micromachines ... Boston-Power
...
Boston
Therapeutics ... Bot Dolly .... Boundless
... BoXZY ..... BrainCells
... BrainScope .... Brain Sentry ....
Brain Tunnelgenix
Technologies .... BrainXell ..... Branch Medical Group ..... Brayton
Energy
.... Breathe
Technologies ... Breonics ... BreviTest
Technologies
..... Brewer
Science ...
Bridgelux
... Brightsource Energy ... Bright View
...
Brimrose Corp of America ... Brock Rogers Surgical ...
Bromium
.... Brooks
Automation ...
Bruker Daltonics .... Buffalo BioLabs ..... Burl
Concepts
..... Burr Oak
C12 Energy ... C3Nano
... C4 Therapeutics .... C8
Sciences ....
C9 ... Cadence Pharma .... CadheRx Therapeutics
.....
Caisson Biotech .... Calabazas
Creek
Research .... Cala Health ..... Calando
Pharmaceuticals
... Calbiotech .... Calera ... Caliber Biotherapeutics ....
Calibra
Medical ... Calient ... Caliper Life Sciences
....
CaliSolar ... Calistoga Pharmaceuticals ...
Calithera
BioSciences .... Calixa
Therapeutics ... Callidus Biopharma ... Calporta
Therapeutics
.... Caltech Metals ... Calysta .... Calyxt ..... Cambridge
Endoscopic Devices ... Cambridge Heart
.... Cambridge
Research & Instrumentation ... Cambrios
Technologies ....
Candela Laser .... Cancer Genetics .... Cancer Prevention
Pharmaceuticals .... CanDiag .... Canopy Biosciences ..... Capesym
... Capio Biosciences .... Capnia
... CAPP Medical ..... Capricor Therapeutics .... Cara
Therapeutics .... Carbon .....
Carbon
Design
Systems ... Carbtex Technology
.... Carbylan Therapeutics ..... Cardeas
Pharma ....
CardiacAssist ..... Cardiac Concepts ...
Cardiac
Dimensions
... Cardiac Science ..... Cardialen ..... CardiAQ Valve
Technologies ... Cardica
... CardioDx
... CardioFocus ... CardioInsight Technologies .....
Cardiokinetix ..... CardioMag ... CardioMEMS .... Cardionomic ....
Cardiorobotics
...
Cardiosolutions ... Cardiosolv .... CardioSpectra ... CardioTech
... Cardiovate ..... CardiOx ...
Cardioxyl
Pharmaceuticals
.... CareDx (formerly XDx) .... Caribou Biosciences
.....
Carigent Therapeutics .... Carnegie Robotics .... Carnegie Speech
... CaroGen .... Carter Aviation Technologies
.... Carticept
Medical ... Cartiva ..... Cascade Designs ...
Cascade
Microtech
... Cascadian Therapeutics (formerly Oncothyreon) .....
Castle
Biosciences ..... Catabasis Pharmaceuticals
... Catadon
Systems
... Catalyst Biosciences ... Catalyze .....
Catelectric
.... Cebix
.... Cedarburg Pharmaceuticals .... CeeTox
... Celadon ... Celator Pharmaceuticals
... Celdara Medical ..... Celladon .... Cellara ....
Cellceutix
.... CellCyte
Genetics
... Celldex Therapeutics
... Cellectar ... Cellerant Therapeutics
... Celleration .... Cell Genesys ... CellRight
Technologies
..... Cellular
Bioengineering
...
... Cellular Bioengineering ..... Cellular Biomedicine Group
.....
Cellular Dynamics International .... Cell>Point
.... CellSavers ..... Cellscape .... Cellscript
..... Cell
Signaling Technology ...Cell
Therapeutics (now CTI
BioPharma)
... CellTraffix ... CeloNova Biosciences
..... Cel-Sci
.... Celsion ...
Celtaxsys ..... Celula...
CellzDirect ... Cempra Pharmaceuticals.
.... CeNeRx
BioPharma ... Centocor .... Centrose ... Centice
...
Centritec
Seals ... Cephalon
... Cepheid
... Cephalon ... Ception Therapeutics
... Cequent
Pharmaceuticals ... Cerebras Systems ..... Ceradyne ...
Ceramitron
... Cerapedics
.... Ceramatec
... Cerevast Therapeutics .... Cerealus Holdings
... Cerecor .... Ceregene ...
Cerahelix
.. Ceres Nanosciences ..... Cerexa .... Cerion
Enterprises ...
Cermet ... Cernostics ..... Cerulean Pharma
... Cerus ... Cervel Neurotech .... Cesca
Therapeutics
....
Ceterix
Orthopaedics ... CFD Research ..
CFX Battery
.... CGI Pharmaceuticals ... ChaCha
... Chantilly BioPharma .... Chapman
Innovations ... Charles River Analytics .... Charles
River
Lab ... Charter Medical ..... Chatham Therapeutics .....
Chemat
... Chembio Diagnostic
Systems .... ChemImage ... Chemir Analytical
Services ...
ChemoCentryx
... Chemtura ....
Chesapeake Sciences
...Chesson Labs ... Chiasma .... Chimerix
... Chlorogen ... Choice Therapeutics
... Chondrogenics
... Chorum Technologies .. ChromaDex
..... Chronix
Biomedical
... Chrysalis BioTherapeutics .... Cibus
Global
... Cidara Therapeutics .... Ciena
....Ciencia ...
Cilion .... CimaBay Thera ..... Ciranova
... Circle
Technologies ..... Cirius Therapeutics ..... CivaTech
Oncology
.... CiVi Biopharma ..... Civitas Therapeutics
..... Claret Medical .... Clarassance ..... Claresta
Solutions
.... Clark-MXR ...Claros
Diagnostics
.... Clean Diesel
Technologies ... Clear Catheter Systems .... ClearCount
Medical
Solutions .... ClearEdge
Power .... Clear Guide Medical .... Clearside
Biomedical ... Cleave Biosciences ... Cleveland BioLabs ...
Cleveland
Polymer Technologies ..... CleverSet ... Clinical Data
... Cloudant ... CloudMade ... Cloud
Pharmaceuticals
(formerly Teradiscoveries) .... Clovis
Oncology ... Clovis Tech ..... CMC Biologics .... C-Motive Technologies
.... CoAxia ....
Cobalt
Biofuels
...
Cocrystal Discovery ... Codexis
... Codiak BioSciences ..... Codon
Devices ... Co-D Therapeutics .... Cofactor
Genomics ....
Cogenra .... Cogentix Medical ..... Cognex
...Cognition
Therapeutics .... Cognitive Code
... Cohera
Medical .... Coherus Biosciences .... Cohesive
Technologies ... ColdWatt ... Collagenex Pharmaceuticals ...
Collegium Pharmaceutical ... CoLucid Pharmaceuticals
... Columbia Labs ..... CombiMatrix ...
CombinatoRx
..... Combined Energies .... Combinent
BioMedical Systems ... Comfort Motion Technologies
...
Commonwealth Biotechnologies ... Compact Membrane Systems ...
Compellent Technologies ... Compendia Bioscience .....
Complete
Genomics ....
Complexa
..... Conatus
Pharmaceuticals ... Concert
Pharmaceuticals
.... Concordia Fibers ...Concurrent Technologies ...
Conductus
.. Confluence Life Sciences ..... ConforMIS ...
Cognigen
.... Conispire
.... ConjuGon .. Connecticut
Valley Bindery ... Consonus Technologies
...
Constellation
Pharmaceuticals .... Contour Energy
Systems ControlRadSystems ..... Conventus
Orthopaedics ..... Convergen
... ConverGene .... Convio .... Convoy
Therapeutics
.... Cool-Bio
.... CoolCAD Electronics .... CoolChip Technologies
....
Cool Earth
Solar
.... Cooligy ... Corbus Pharmaceuticals
..... Corcept
Therapeutics
...
Cordex Systems .... CoreStreet ... CoreTek ...
.Corgenix
Medical
... Corindus ....Corinthian
Ophthalmic ... Corium International .... Corixa
....
CorMatrix
Cardiovascular
.... Cornami ..... Cornerstone Research
... Cornerstone BioPharma then Cornerstone
Therapeutics
..... Cornerstone Therapeutics .... Coronado
Biosciences ... CorQuest Medical ..... Correx ... Corridor
Pharmaceuticals
... Cortana ..... Cortendo AB ..... Cortexyme ....
Corvus
Pharmaceuticals
..... CosmosID ..... CoStim Pharmaceuticals
.... Cougar
Biotechnology ...
Coulbourn
Instruments .... Coulter Pharmaceuticals ... Cour
Pharmaceutical
Development .... Coverity ..... Creare ...
Creative
Hybrid Solutions .... Creatv MicroTech .... Cree
Research ... Crescendo Bioscience .... Crinetics
Pharmaceuticals
....
CrispTek .... Critical Therapeutics .... CritiTech
... Crossbar .... Cross Current ..... CrossFire
... Cruise Automation .... Crux Biomedical
...
CryoCor ...
CryoLife ...
Crystal IS ... Crystal Systems ... Crystallume ... CSA
Engineering ... CS-Keys ... CTD Holdings
..... CTI
BioPharma (formerly
Cell Therapeutics) .... Cubist
Pharmaceuticals
... Cue Biopharma .... Cumberland Pharma .... CuraGen ... Current Motor
...
Curtana Pharmaceuticals .... Custom Electronics .... CVD
Equipment ..... CVRx
... CV
Therapeutics ... Cyanotech ..... Cyberdyne .... CyberKey Solutions
... Cyberkinetics Neurotechnology ... Cybernet Systems
... CyberOptics ... Cydan .... CymaBay
Therapeutics
.... Cymbet ... CyMedica Orthopedics ..... Cymer
...
Cynosure ... Cyntellect ... Cypher Genomics ... CyPhy Works
... Cypress Bioscience ... Cyrus Biotechnology .....
Cyterix
Pharmaceuticals ...
CytImmune .... Cytocentrics ..... CytoCore (formerly Molecular
Diagnostics) ..... CytoDyn
.... Cytogel Pharma
....
Cytokinetics
... Cytometix ....CytomX ...
Cytonome
....
Cytori Therapeutics ... Cytophil CytoSolv
... Cytosorbents ..... Cytovas ... CytRx ..... Cytyc
...
CyVek
Dabble ..... Dairyvative Technologies ..... Daktari Diagnostics ... Dance Biopharm .... Dara BioSciences ... Dart Therapeutics ... DaStrong .... Datafiniti .... Data Physics ... DataRobot ..... Dato (formerly GraphLab) .... Datuit .... daydream.io ..... Daylight Solutions .... DayStar ... DBS Energy ... DCL Medical Laboratories ... Deca-Medics ... Decibel Therapeutics ..... DecImmune Therapeutics ... Deciphera Pharmaceuticals ..... Decision Biomarkers ... Deepwater Wind .. Defense Engineering .... Defense Research Associates .... Defibtech ... Dekkun .... Delcath ... Delinia ..... Deltanoid Pharmaceuticals ... Denali Medical ... Denali Therapeutics ..... Dendreon ... DeNovo Sciences .... DeNovis ... Deposition Sciences .... DermAvance Pharmaceuticals ... Dermira ... Desalitech .... Descartes Labs ..... DesignMedix ..... Detcon ..... DE Technologies ... Devicix ..... Dew & Ken Group ... Dewey Electronics ... Dexcom ... Diagnostic Biochips .... Diagnostic Hybrids ... DiaMedica ..... Diamond Foundry ..... Dicerna Pharmaceuticals ... Diffusion Pharma ..... DiFusion Technologies ... Digene ..... Digirad ... DigiSight Technologies ..... Digital Fusion ... Digital Lumens ... Digital Optics ... Dignify Therapeutics .... Dimension Therapeutics .... DioGenix .... Dipexium Pharmaceuticals ..... Directed Manufacturing .... Directed Perception .. Disc Dynamics ... Discovery Genomics ..... Discovery Labs .... Displaytech ... Distributed Energy Systems ... Divergence ... Diversified Energy ... D. Light ... DNAnexus ..... DNAPrint Genomics ... DNAtrix .... DNV GL .... DoX Systems ... Dragon Systems .. Dragoon ITCN ..... Drilling Info ... DrillMap .... DropWise .... DR Technologies ..... DSM .... DT Solar ... DuBay Ingredients ... duPont Aerospace ... Dura Biotech .... Durata Therapeutics ... Durin Technologies .... DVS Sciences .... DxUpClose .... Dyadic International ..... Dyax ...DynaBil Industries ... Dynasil ... Dynavax Technologies ... Dynogen Pharmaceuticals
E3 Clean .... Eagle
Optoelectronics ... Earl Energy .... EarLens .... Earth Networks ....
Earthrise
Nutritionals ... eASIC ..... Eboo Pharmaceuticals .... EBR
Systems ..... Ebullient
....
Echelon .... Echodyne
..... Echometrix ... EchoPixel ..... Echo Therapeutics (was
Sontra)... ECI Biotech
... ECM Technologies ..... Ecocurrent
... EcoPesticides .... EcoPro Polymers .....
Ecovative
Design ... Edaptive
Computing .... Eden
Bioscience
... Edenspace
Systems ... Edico Genome .... Edison Agrosciences ..... Editas
Medicine .... EEStor
... Effector
Therapeutics .... Egalet .... eGenesis .... Eikos ... E-Ink
... EIS .... Ekos ... EKR Therapeutics .... Ekso
...
Elcelyx Therapeutics ... ElectroCell
Technologies
... ElectroChemical Systems ... Electro Energy
...Electromed ... Electro Optical Sciences ...
Electro
Scientific ... Elemetric Instruments
... Elevation Pharmaceuticals ... Eleven
Biotherapeutics ... Elira Therapeutics
..... Elixir
Pharmaceuticals ...
Elixir Biopharm ... Ellipse Technologies ..... Elon ...
eMagin .. Embera
NeuroTherapeutics .... EmboMedics .....
Embrex ..
EMCORE
...
Emerald BioStructures
.... Emergent BioSolutions ...
Emergent
Technologies ... Empire Genomics .... Empire
Robotics ....
EMRes Technologies
... Emulate .... Enable
Injections ...... Enanta Pharmaceuticals ..... EnChroma ..... Encite
...
Encoded Genomics .... Encore
Vision .... Encysive
Pharmaceuticals ... Endeavor Robotics ..... Endece
...
Endgame Technologies
... EndoChoice .... Endocyte ... EndoGastric
Solutions
... Endo International ..... Endoscopic
Technologies ... Endosee ..... EndoStim
.... Endotherapeutics ..... Ener1
... EnerG2 ... Energen
... Energesis Pharmaceuticals .... Energetiq
Technology ... Energid Technologies ...
Ener-G-Rotors
... Energy Control ... Energy Conversion
Devices .
.. Energy Focus ..... Energy Recovery ... Energy
Solutions
... Energy Storage Systems ..... EnerMat Technologies .....
EnerMed ..... Enertech
Environmental ... EnerVault ... Engineered
BioPharmaceuticals
.... Engineered Propulsion ...Engineous
Software
... Enlibrium ..... Enlight
Bioscience ... EnSync Energy Systems (formerly ZBB Energy)
.....
Ensysce Biosciences ... Entasis
Therapeutics ..... Entech
... Entegrion ... Entellus Medical .....
Entergem
Ventures ....
EnteroMedics
... Entia Biosciences ..... Entopica Therapeutics
...
EntreMed
...
Entra Pharmaceuticals ... ENTrigue Surgical ...
Envia
Systems .. Entrotech Life Sciences ..... Entvantage
Diagnostics
..... EnviroFlight ..... Envisia Therapeutics
..... EnVivo
Pharma ... Enzenia ... Enzium
... Enzo Biochem ... Enzymatics ... EnzyMed ..... EO2
Concepts
.... EOIR
... Eonix ....
EpiBiome ....
EpiBone .... Epicentre
Biotechnologies .... Epic Sciences .... Epic Systems ..... Epicypher
.... EpiEP ...
Epion
... Epiphany Solar Water Systems .... Epitomics
...
Epiva Biosciences ..... EpiVax ... EpiWorks .... Epix
Pharmaceuticals ... Epizyme
...
Eppin Pharma .... EqualLogic ... Equex
... Equipment
Concepts ...
EraGen Biosciences ... Erallo Technologies ...
Ercole
Biotech ...
Escalon Medical .... Escoublac ....
eScription
... eSolar ... Eso-Technologies
... Esperance Pharmaceuticals ..... Esperion
Therapeutics
..... Essential Biotechnology
..... Essential Medical .... Essentient ....
Essex... Eta Devices ..... Eta-Gen .... Etegent
Technologies
... E-Tek
Dynamics ... Euclid
Labs .... Euclises Pharmaceuticals ..... Euthymics
Bioscience ... EVapt .... Evelo
Therapeutics ....
Evena Medical ..... Ever Cat Fuels
...
Evergen Biotechnologies ... Evergreen Solar ... Evestra ....
Evident
Technologies ... Evoke Pharma .....
Evolution
Robotics ...
..... Evolv
.... EWI .... Exact
Sciences .... Exagen
Diagnostics ... Excelimmune ... Excel
Technology .... Exelixis ..... Exelixis
Plant Sciences ... Exemplar Genetics .... Exo .....
Exogenesis
..... Exone ....
Exosome Diagnostics ..... Exovita
Biosciences .... ExploraMed
NC4 ...
Expression
Analysis ....Exsulin
....Extreme Molding ... Extremity Innovations ... EyeGate
Pharmaceuticals ... EyeNetra .... EyeTel
Fallbrook
Technologies
... Famigo ... Faraday Pharmaceuticals .... Farodox
Energy
Storage
...
FarSounder ... Far-Tech.... FastCAP Systems ...
Fate
Therapeutics
... Fathom .... Fe3 Medical .... FEI ... Femasys
.... Femta
Pharmaceuticals
.... Ferrate
Treatment Technologies ... FerroKin BioSciences ....
Feuz Manufacturing ... Fiber and Sensor .... Fiberight ...
Fiber Materials ... Fibersense ... Fiberstar ....
Bio-Ingredient
Technologies
Fibrocell Science ... FibroGen ... Filter
Sensing Technologies ...
FineLine Prototyping .... Finisar ... Fire Alarm
Specialty Design .....
Firefly
BioWorks ... Firefly Energy .... Firefly LED
...
First Solar ... Fisker Automotive ... Five Prime
Therapeutics .... Flex Biomedical
... Flexion Therapeutics ... Flextronics
America ....
Flexus Biosciences .... FLIR Systems
.. FloDesign
Wind Turbine ... FlowCardia
...
FlowMedica .... FlowMetric .... Flow Metrix
...
FluGen
... Fluidic Energy ... Fluidigm ... Fluid Innovation
Group
... Fluidnet ... Fluidnet
FluoroPharma
... Fog Pharma ..... FokusLabs .... FoldRx Pharmaceuticals
...
Follica ...
Footnote .... Foresight Biotherapeutics .... Forge Therapeutics .....
F-Origin
... Forma
Therapeutics ...
Formlabs
.... For-Robin ..... ForSight Vision5 .... Fortis Therapeutics .....
Forty Seven ..... Forum Pharmaceuticals ..... Forus
Health ... Foster-Miller .... Foundation Medicine
... Fox Chase Chemical Diversity Center ....
Fractal
Antenna Systems ... Freedom Meditech
... Free
Flow Power ... Free Form Fibers .... Freenome ..... Frontier
NanoSystems .....
FTL Solar ...
FuelCell Energy
... Fuel Tech
.. Fulcrum Therapeutics ..... Fulgent Therapeutics ..... Full
Spectrum Genetics .... Furiex
.... Fused
Innocation.
...
Fusion
Coolant Systems
G1 Therapeutics ..... Galenea ... Galena
Biopharma
.... Galera
Therapeutics ..... Galil Medical ..... Galleon
Pharmaceuticals ... GAM Enterprises .... GameSalad
... Gamma Medica Ideas ... Garland
Technology .....
Garwood Medical Devices ..... GATR Technologies ..... G-Con .... Gecko
Biomedical .... Gel Combs .... Gelesis ...
Geltech ...
Gema Diagnostics .... GEMFIRE .. Gemin X Pharmaceuticals
... Gemmus
Pharma ... Gmphire Therapeutics ...... Gemstone
Biotherapeutics
..... Gen9 ...
Genaera ...
Genalyte
... Genapsys .... GenAudio .... Gene by Gene .... GeneCentric
Diagnostics
...
Genelabs
Technologies ... Gene
Logic ... General Compression ... General
Pneumatics
..... Generex
Biotechnology ... Gene Security Network .... GeneSegues
Therapeutics ..... GenesisLabs ....
GeneSystems ... Genetesis .... Genetic Networks ..... Genetix
Pharmaceuticals
... Geneu .... Genia Technologies .... GenMark Diagnostics
....
Genocea
Biosciences
... Genomatica
... Genome Profiling ... GenomeQuest ... Genomic Health
...
Genomind ....
Genoptix
Medical
Laboratory ... Genor ... Genprex .... Gen-Probe
...
GenSpera
.... GenTel BioSciences ... Gentris ... GenturaDx
...nbsp; GenVec ... GenWay Biotech ..... Genzyme .... Geocent
.... Geocove ..... Geomagic
... GeoMed
Analytical ... GeoVax Labs ...
Geospiza
... Geron ... Gevo
..... GI Dynamics
...
GigOptix
... Gilead Sciences .... Giner . ..
Ginkgo BioWorks
.... Glauconix ..... Glaukos
.... GlideLine
Systems ... Gliknik ... Global Blood
Therapeutics
...... Global Cancer Diagnostics ..... Global Positions ...
Global Blood Therapeutics ....
GlobeImmune ....
Gloucester Pharmaceuticals ... Glowforge ..... GlucaGo ...
GlycoFi
... GlycoMimetics .... GlyGenix ... Glyscend .....
GlySens
... GMZ
Energy
... GnuBio
.... Goddard Labs .... Goldfinch Bio ..... Good Start Genetics
.... Gore
Photonics ... Gotham Biotech .... GPC-Rx
... gRadiant Research ... Gradiant ....
GraftWorx
..... Grail ..... Graphene
Energy
... Graphenix Development .... Graphic
Surgery ... GraphLab (now Dato) .... Grassroots Biotechnology
...
Greatbatch
... GrayBug ..... Graybug Vision ..... Great Basin Scientific .....
GreatGrow Maryland ....
GreatPoint Energy
... Green & Grow .... GreenFuel
Technologies .... Greenlight Biosciences .... Green Mountain Radio
Research .... GreenSight Agronomics ..... Green Sulfcrete
.....
GreenTech America
... Greenwich Geriatrics .... GridBridge .... Gritstone
Oncology
..... Group14 Technologies ..... Grove
Instruments
... Grow Home Organics
.... GSI Technology ... GT Advanced
Technologies ...
GTC Biotherapeutics ... G-Tech Medical .... GT
Equipment .... GTI
Diagnostics
... Guardant Health .... Guided Surgery Solutions
....
Guided
Therapeutics
.... .... Guided Therapy Systems ..... Gynesonics .....
G-Zero
Therapeutics
H2O Score ..... H2Pump ...
H2Sonics
.... H3
Biomedicine ... HNC Software ... Halozyme ...
Hana
Biosciences .... Hansen Energy and Environmental
....
Hansen Medical ... Haplogen Genomics ..... Harbor
Technologies .. Hardcore Computer ... HarkerBio .... Harmony
Enterprises ....
Harpoon Medical ....
Harvard Apparatus
Regenerative Technology .... Harrisvaccines .... Harvard Bioscience
... Harvest Automation .... Harvest Power ...
Harvest Technologies .... Healionics .. Health Diagnostics
Laboratories .... HealthMyne ....
Healthtronics
.... Hearforward
... Heartland Robotics .... HeartWare International
... Heat
Biologics .... ... HeatGenie ... Helicos
BioSciences
... Helion Energy .... Heliovolt ...
Helius Medical
Technologies ..... Helix
Therapeutics
... Helomics (formerly Precision Therapeutics)
.....
Hemadvance ..... HemaQuest Pharmaceuticals ... Hemarrest ... Hemera
Biosciences .... Hemispherx Biopharma .... HemoGenyx .... Hemostasis
... Hennepin Life Sciences .... Hepregen ... Heraeus Medical
Components .... Herley Industries
... Hermes Biosciences ... HexaTech
.... Hexfuel .... Hibernaid .... High Impact
Environmental
.... High Performance
Technologies ... High Point Pharmaceuticals .....
Histogen
.... Histogenics
... HistoRx
... HistoSonics .... HJM
Precision .....
HocusLocus ..... Hoku
Scientific
... Holaira .... Hollingsworth & Vose .... Hollis-Eden
Pharmaceuticals ... Holomni .... Homology Medicine
.....
Honeycomb Batteries .... Hontek
... Hoopers Island Oyster Aquaculture ...
Hoppe Tool
.... Hsiri Therapeutics ..... HTG Molecular ..... HTSS
...
Humacyte
...
Humanetics ..... Human
Genome
Sciences ...
Human
Metabolome Technologies .... HuTerra .... Huya Bioscience International
.... Hybritech ..... Hybrivet .... HYCOR
Biomedical ...
Hydra Biosciences ...
HydroCision ... Hydrogen
Safety ... HydroLogic Industries .... Hygeia
Therapeutics
... HyperBranch Medical
Technologies ... Hyperion Therapeutics ... HyperMed
... HYPRES .. Hy-SyEnce
... HyTrust
IAP ... IBC Advanced .... iBiquity Digital ..... Ibis
....
Iblogix
.... IBT
Laboratories
... Icagen .... Icardiac.... Ichor Medical Systems .... Iconic
Therapeutics ..... Icos.... ICX....
Idaho.... Ideal
Converters ... Ideapaint.... Ideaya Biosciences ..... ID Genomics ....
Idevices
... IFM Therapeutics ..... Igenica
Biotherapeutics .... Ignyta.... Ii-IV
.... Ikaria... Ikonisys... Illinois Superconductor.... Illumigen....
Illumina.... Illuminating Diagnostics ..... Illuminoss....
Illumitex.... Imagevision.... Imaging
Biometrics... Imagineoptix ... Imago Instruments... Imanis
Life...
Imbed Biosciences... Imetalx... Immco... Immersion... Immtech...
Immucell .... Immucor ....
Immune... ... Immune... Immune Pharma .... Immunetics...
Immunex...
Immunexcite...
Immuneworks... Immunexpress ..... Immunicon... ImmunoCellular Thera
.... ImmunoChemistry
Technologies ..... Immunocore...
Immunogen... Immunome ..... Immunomedics..... Immunomic Therapeutics
.....
Immunophotonics ... Immurx... .... Immusant...
Immusoft ...
Impact
Science... Impel
Neuropharma... Imperium Renewables... Impinj... Implant
Sciences... Impossible Foods .... Imprimis Pharmaceuticals .... Imprint
Energy .... Impulse
Monitoring ... Imris .....
Imthera...
I-nalysis ... INCELL .... Incelldx ..... Incitor (now XF
Technologies) .... Incontrol
Research... InCube Labs ..... Incyte... ....Incytu... Indalo
Therapeutics ..... Indiana
Nanotech... Indi Molecular ... Industrial Heat ..... Industrial
Perception...
Inentec ... InfaCare Pharmaceutical .... Infarct Reduction
Technologies .... Infinera...
... Infinia... Infinity... Infinium
.... Inform
Genomics... Infoscitex... Inframat... Infraredx... Infrascan... Inf
Robotics ... Infusion Medical ... Ingeneus... Ingeneron .....
Inhibitex... Inhibkase
Therapeutics .... INI
Power... Inland Labs ..... Inmobly .... InnAVasc Medical ....
Inneroptic...
Innerpulse... Innocrin Pharmaceuticals ..... Innography...
... Innopad... Innotec ..... Innovalight...
Innovari Energy Design Microplate Scientific...
pulmonary solutions.... silicon... Innovative Spinal...
Innovative... Innoventiontech... Innovention (now
Ccardiorobotics) ... Innovative Trauma or... Itraumacare...
Innovolt ... Innowave... ... ...
Innov-x...
Inorganic Specialists... Inotek... Ino .... Inova
Labs
Biomedical... Inovio... Inovise Medical ..... Inphase...
... Inphi... Inpria...
Insert MRI... Insight... ..Insite Vision...... Insitu...
Insmed... Inspired Solar Systems ... Inspire... Insulet
Labs
... Intact Vascular... Intaglio... Intalio ... Intarcia
Therapeutics ...
Integenx... Integra Group Diagnostics... Integral Molecular .....
Integrated BioTherapeutics
.... Integrated
Diagnostics .... Integrated
Diagnostics InDi .... Integrated DNA Technologies ..... Integrated
Fuel...
... Integration Associates... Intelect
Medical
Intelleflex ... Intellia Therapeutics .....
Intellicyt
Automation Bio-systems ...
Intelligent Devices .... Intelligent Epitaxy Technology .....
Intellimedix ..... Intelliphage.... Intellirad
Control...
.Intellisense .... Intelomed ....Inter-4... Interactive Supercomputing
... Interdigital
Interlace ....
Intermagnetics General ...Intermolecular ... Intermune....
International Stem Cell ... Interrad Medical ..... IntersectENT ....
Intersense...
Intersystems ...
Intervalve....
Intevac.... Intra-Cellular Therapies .....
Intralase ...... Intrexon ..... Intrinsity.... Introgen....
... Intuitive Biosciences .... Intuitive Surgical.... Invenra ....
Invensense .... Inventev ..... Inverness
Innovations.... Invertix.... Invictus.... Inview Technology....
Inviragen.... Invisage Technologies ....
....InvisionHeart .... Invision Medical ....
Invitae....
Invitrogen.... ...Invivosciences.... Invivo Therapeutics=
Holdings .... Invuity....
Inx Medical.... IoGyn .... Iomai.... ... Iomed....
IOmet
Pharma ..... Ion
America
Optics.... .. Ion Torrent.... Iovation.... Iowa Thin Film....
Ipierian.... IPG Photonics.... ... Iquum
...Irhythm...
iRobot... Iroko...Ironbridge.... ... Ironwood....
... .... Irvine Sensors... .... biopolymer
. .... Ischemia Care.... iSIGHT Partners
.....
Isis.... Island Ddata....
Isogenis.... Isomark.... IsoPlexis .... Isoray....
Isothermal....
Isthmus Biosciences ..... IstoTechnologies....
itaconix....
I-Therapeutix..... Itherxm Pharmaceuticals....
.. Itseez ..... Itzbig ..... Iwalk
Jade Therapeutics ..... J&Y ... Janssen Biotech .... Janus Biotherapuetics ... Javelin Pharmaceuticals ... Javelin Semiconductor ... JDP Therapeutics ..... Jennerex ... Joule Biotechnologies .... Jounce Therapeutics .... Joyent .... Joylux .... Juno Therapeutics ..... Just Biotherapeutics
K2M .... K2 Therapeutics .... KAER
Biotherapeutics .... Kala
Pharmaceuticals ... Kallyope ..... KaloBios
Pharmaceuticals
..... Kalon
Biotherapeutics ..... Karyopharm Therapeutics ... Kateeva ..... Kayo
Technology ..... KaZaK
... KC BioMediX ... KCI .... KDH Defense Systems
...
Keithley Instrument ... Kelyniam ... Kenall
Manufacturing
..... Kensey-Nash
... Kent Displays ... Kentucky
BioProcessing ....
KeraNetics .... Kilawatt
Technologies ... Kindara .... KinDex ... KindHeart ..... KineMed ....
Kinestral Technologies ..... Kineta ...
Kinetic
Concepts .... Kinex
Pharmaceuticals .... Kingbright .... Kior .....
Kips Bay
Medical ... Kite Pharma ..... Kitware ...
Kiva Systems ... KLD
Energy Technologies .... KMel Robotics .... Knightscope
.....
Knome ...
Knopp
Neurosciences .... KnuEdge .... Kodiak Sciences .... Kolltan
Pharmaceuticals
...
Komoku ... Kona Medical .... Konarka ... Koning ...
Kopin
.. KOR
Electronics ...
Koronis Pharmaceuticals ... Kosan Biosciences ... Kosmetikos
....
Kovio ... KPI
Therapeutics (from Kineta)... Kraig Biocraft ..... Kratos Defense
& Security
Solutions
.... Kronos Advanced
Technologies ... KSE
... Kultevat ..... Kura Oncology .... Kumu Networks .... KVH
.. Kylin
Therapeutics
...
Kyma .... Kymeta
... Kyocera
Solar .... Kypha ..... Kyras Therapeutics ..... Kyron
Clinical Imaging
LAAMScience ... LaBelle
Associates .....
LabNow
...Laborie Medical Technologies ... Labrys Biologics ... Laguna
Pharmaceuticals (formerly ChanRx) ..... La Jolla
Pharmaceutical
... Lake Shore Cryotronics .... Landec
.... Lantern
Pharma ..... Lantheus
...
Lantos
Technologies ... Lariat Biosciences .... Laser
Design .... Lasergen ..... LaserMax ..... LaserMotive
... Laser Tissue
Welding .... Lattice Biologics ..... Lattice
Biotech ....
Lawrie ... Lazarus Effect ..... LDR
Holding
..... Lead
Therapeutics
... LeafBio .... LeCroy ... LED Lighting
Fixtures
... Lehigh
Technologies .... Leica Microsystems
.....
LetoSolutions .... Lexicon
Genetics
... Lexicon Pharmaceuticals ... Leyden Energy ... Libra
BioSciences .... LifeCell ... LifeGen
Technologies ...
Life Image ... Life Technologies ....
Ligand
Pharmaceuticals ....Ligon Discovery ... Lightpointe
... Light Sciences Oncology ... LightWorks Optics
....
Lilliputian Systems
.... Lily Robotics ..... Linares Management
Associates
.. Lingotek
... Lionano .... Lion Biotechnologies ..... LipoScience ...
Liquid Biotech ..... Liquidia
Technologies ...
Liquid Light ...
Liquid Metal
Battery ...
LiquidPiston ... Liquid Robotics ... Liquid X Printed Metals
....
LiQuifix ...
Lithium Technology
... LiveData ... . LiveLeaf
Bioscience ....
Logical Therapeutics
... Lodo Therapeutics .... Logos Tech ... Lohocla Research
.....
Lombard Medical .....
LonoCloud .....
Lookingglass ..... Loon Medical
..... Lotus Tissue
Repair
...
Loxo Oncology ... LPath Thera .... Lq3 Pharmaceuticals ....
LS9
...
Luca
Technologies .... Lucerno Dynamics .... Lucidux ...
Lucigen
.... LumaSense Technologies .... Lumena
Pharmaceuticals .... Lumencor
... Lumense .... Lumera ... Lumicell Diagnostics
...
Luminary
Micro ...
Luminex .... Luminus Devices ... Lumitex
... LumiThera .... Lumos Pharma .... Luna Innovations
... Luna
Technologies
... Lung Therapeutics .... Lutonix
...
Luxtera
... Lycera ... Lyncean ..... Lynntech ... Lysosomal
Therapeutics ....
Lytro Therapeutics
M3 Biotechnology .... MabVax .... MacAulay-Brown
..... Macrochem ...
MacroFab ..... Macrogenics
... Macrophage Therapeutics .... Madison
Vaccines .... MagBioSense ..... Magenta Therapeutics ..... Magic Leap
..... MagneMotion ...
Magnesium Development ..... Magnetek ... Magnolia
Medical
Technologies .... Magnolia Optical
Technologies
... Magnolia Solar ... Mainstay Medical International ......
Mainstream Engineering ... Major
Pharmaceuticals .... Mako Surgical
... Manhattan Scientifics ..... MapInfo ...MAP
Pharmaceuticals
... Mapp
Biopharmaceuticals .... Marathon Pharmaceuticals ..... Marcadia
Biotech
... Marina Biotech ... Marinus
Pharmaceuticals
... Maritime Applied Physics .... Marrone Bio Innovations
....
Martek Biosciences ...
Mascoma ... Mashery
... Mason Box ... Masten Space Systems
... Masterson Industries .... Mast Therapeutics
(formerly
ADVENTRX) .... Material Sciences ... Material
Technologies ... MathStar ... Mati
Therapeutics .... Matouk
Textiles ... Matritech ... Matrix Product Development
.....Matrix
Research ....
Matrix Sensors ... Maverick Therapeutics ....
MaxCyte
...... Maxdem
... Maxpower ... Maxygen ....
MBio Diagnostics
.... MC10 .... MCube .... M
Cubed Technologies .... MD Biosciences ..... MDSolarSciences
... Mebias Discovery ..... Mechanical
Technology
...
Mechanology ... Medafor ...
Medarex ...
MediBeacon .... Medicago USA .... Medical Cyberworlds .... Medical
Device Logistics ...
MedicaMetrix... Medgenics .....
MedImmune ..
Medina Medical .... Mediomics ....
Medis
... MEDITE Group .... Medivation ... Mednology Solutions ....
Medrobotics ...
MedShape .... MedSocket (formerly 1CDS) ...... Medsphere Systems .....
MedTel ..... MEI Pharma
..... Meka .... MELA
Sciences .... Melinta Therapeutics .... Melior Discovery .... Memjet
...Memry ...
Memsic ... MEMS Optical...MER
...
Mercator Therapeutics ... Mercury Computer
Systems .... Merganser Biotech ....
Merge
Technologies ... Meridian Bioscience
... Meritage Pharma ..... Merkatum ... Merrimack
Pharmaceuticals
... Meryx .... Mersana Therapeutics ... Mesa
Photonics ... Mesocopic
Devices ... Metabasis ... Metabiota .... Metabolic Solutions
Development .... Metabolex .... Metabolix
... MetaCarta ... Metacrine .... Metal Oxygen
Separation Technologies ... Metamark Genetics ...
MetaModix
... Metompkin Seafood .... MetroLaser ... MGC
Diagnostics
...
Misaole .... Micell
Technologies
... Michelman ... Micracor .... Micrel ... MicroCoating ...
Micracor ....
Microbe Detectives
... Microbia ... Microbot Medical ... Microfluidics International
(Microbia)
... MicroGreen
Polymers .... MicroIslet ...
Microlin Bio ....
MicroMask ...
Micronics ... MicroOptical (New
Mexico)... MicroOptical
(Massachusetts) ... MicroOptx ..... MicroPower Technologies
...
MICROrganic Technologies .... MicrowSat
Systems .... Microscopy Innovations ..... Microstaq
... MicroTransponder ..... Microvision ... MicuRx
Pharmaceuticals
.... Midori Renewables
..... Mid Valley
Industries
... Millendo Therapeutics (born as
Attercor) .....
Miltec .... MiMedx Group .... MimiVax ....
Minerva
Biotechnologies
... Minerva Neurosciences .... Minerva Surgical
....
Minimally Invasive
Devices ....
Minnesota
Thermal Science ..... Minnetronix ... MIOX ..... Mirador Biomedical
... Mira Dx ... MiRagen
Therapeutics .....
Miramar Labs .... Mirimus ...
Mirina ...
Mirna
Therapeutics.... Miromatrix Medical ...
Mirus Bio ...
Mission Research ... Mississippi Polymer ... Mithridion ...
Mitochon Pharmaceuticals ..... Mnemosyne
Pharmaceuticals ...
Mobile Robots ... Mobius Therapeutics ..... Moderna Therapeutics ....
Modern Technology Solutions
.... Moduline Systems .... Modumetal ..... MOgene Green Chemicals ....
Molecular
Biometrics
... Molecular
Detection ... Molecular Diagnostics .... Molecular Imprints
... Molecular
Insight
Pharmaceuticals ... MolecularMD ... Molecular
Sensing ...
Molecular
Templates
.... Moleculin Biotech ..... Molten
Metal .. MoMelan Technologies ... Momenta
Pharmaceuticals ... Monebo ... Monogram Biosciences
.... Monteris Medical ..... Morphic Therapeutics
.....
Morphormics
... Morphotek
...
Morris
Innovative Research ... Mortara Instrument ...
MortaSecurity .... Motricity
... Mound Laser
& Photonics Center ..... Movia Robotics ..... Moximed .... MPP
Group ... MPSP ...
MSNW ....
Mudawar Thermal
Systems
.....
Munksjo Paper ... Muons ... Muse bio .... Myco
Technology
....
Myocor
... MyoKardia
...
Myomo
... Myovant Sciences ..... Myriad Genetics
...
Myriant
Technologies
... Mystic Pharmaceuticals
N12 Technologies
... (N30 Pharmaceuticals) now Nivalis Thera .... NABsys
... Nalas
Engineering ....
NanOasis Technologies ... NanoBio
...
Nanobiosym ... Nano-C ... NanoCellect (formerly NanoSort)
.....
Nanocomp Technologies ...
NanoCoolers ... Nanocopoeia ... NanoCor Therapeutics
...Nanodynamics (Buffalo) ... Nano DX ..... Nanodynamics
(NYC)...
NanoeXa
.... Nanofiber Solutions ... Nanogen ... NanoGram .... nanoGriptech
..... NanoH2O
... Nanohmics ... NanoLab
... NanoLite Systems ... NanoLogix ...
NanoLumens
..... Nanomaterials
Research
... NanoMatrix ... NanoMedex ... NanoMedicalSystems
...
NanoMedical Systems .. Nanomix ... nanoMR ..... Nanophase
Technologies
... NanoPhotonica ... Nanopore Diagnostics ..... Nanoptek ...
nanoRETE .... Nanoscale
Components ...
Nanoscale
Materials
... Nanosolar ...
Nanosonic ... Nanospectra Biosciences .... Nanosphere ... NanoSteel
...
Nanostim .... NanoString
Technologies .... Nanosys ...
NanoSystems ... Nano Tailor ... Nanotek Instruments
.....
Nano-Terra ... Nanotherapeutics ..... NanoTune Technologies
... Nanova
....
Nanovation
Technologies ... NanoVault Medical .... NanoViricides
... NanoVision Diagnostics .... Nantero
... Napo
Pharmaceuticals ... NantKwest ..... Narus
Biotechnologies ..... Nascentric
... Nastech
Pharmaceutical ... Natera .... National Technical Systems
..... Natural Molecular Testing ..... NaturalNano ...
Nature's
First .....
Natus Medical ... Naverus ... Navidea
Biopharmaceuticals ... Navini Networks
... Navitor Pharmaceuticals .... Navmar Applied Sciences
... NBD Nanotechnologies ....NCD Technologies
.... nContact
Surgical ...
Neah Power ... Near Infinity .... Neato Robotics ... Nektar
Therapeutics ... Nekton
Research
.... NemaMetrix .... NeoChord ... Neogen
....
Neograft
..... Neon Therapeutics .... NeoPhotonics
...
Neoprobe
...
Neos Therapeutics ..... Neothetics .... Neotron ...
NephroGenex .... Nereus
Pharmaceuticals ... Nest .... Netezza ... NetLogics
Microsystems... Netspeed Systems ...... Net Watch
Solutions
..... NetworkFab
...
NeurAccel
Biosciences ...
Neurala .... Neuralstem .... Neuro Amp .... Neurobiological
Technologies
...
NeuroChaos Solutions .... Neurocrine Biosciences
...
NeuroDx Development ... NeuroEM .... Neurodyne Medical ...
Neurofluidics .... Neurogen
... NeurogesX ...
Neurognostics .. NeuroHabilitation .... NeuroLogica
.... NeuroLutions ..... NeuroMap
... Neuro Kinetics ....
NeuroMetrix... Neurona Therapeutics .... Neuronetics .
Neuronex .. NeuroPace
...
NeuroPhage
Pharmaceuticals
... Neuron Systems ...
Neuroptix ... Neuroscience .... NeuroTek .... Neurotrack ....
NeuroTronik .... Neurotrope ..... Neurovance
... NeuroVigil ...
NeuroVision Imaging .... NeuroVista ....
NeuroVive
.... NeuWave
Medical ...Nevro ... NewLeaf Symbiotics .... NewLink Genetics
.... Newlink genetics england ... biolabs ...
new
era technology ... New Haven Pharmaceuticals ... Nexant
...Nexbio
... NexImmune .... NexPlanar .... NextCure ..... Nextio ....
NEXTracker
....Nextreme Thermal Solutions ... Nexus
Biosystems ... NG1 Technologies .... NGM Biopharmaceuticals .... Nico
..... Night Vision ...
Nimblegen Systems ... Nimble Storage ....
Nimbus Discovery ... Nimbus Therapeutic
.....
Ninepoint
...Niowave ... NIRvana Sciences .... Nitero....
Nitric Biotherapeutics
....Nitricgen ... Nitride Solutions .... Nitrogenics .....
Nitromed ...Nitronex
... Nivalis Therapeutics formerly N30 Thera ..... NKT
Therapeutics ...
Nlight ... NMT Medical .... Noah
Technologies ....
Noble Fiber
... Nohla Therapeutics .... Noivatone .... Nok Nok
Labs
....
Nomadics .... NONA Composites .... Noninvasix ....
Nonvolatile
Electronics .... Nora Therapeutics .... Norian ... NorMedix
.....
Normoxys
.... Norse .... Northeast Photosciences
... Northstar Medical
Radioisotopes .... Northstar Photonics...
Northwest Biotherapeutics .. Norwich Technologies .... Notice
Ttechnologies ... .Novacea
... Novalar Pharmaceuticals ... Novalux
... Novan
Therapeutics .... NovaScan
... Nova Synthetix .... Novatek ... NovaTorque
... NovaTract
Surgical
... Novavax .... Novazyme Pharmaceuticals ..... Novecon
Technologies ... Novella
Clinical
.... Novelos
Pharmaceuticals
... Novelos Therapeutics ... Noveome Biotherapeutic
.....
Novian Health .... Novira
Therapeutics ...
Novocell ... Novogy
... Novomer ...
Novophage ... Novo Sol-u-tions MD .... Novosource ...
Novozymes .... Novus Biologicals ....
Noxilizer
... Nox Technologies ... NP Photonics ...
NPS Pharma ..... NRGindependence ..... NSS Labs
..... Nucelis
.... Nuclea
Bioechnologies ... Nufern .... NuGEN Technologies .....
NuMedii
.... NumereX .... NuPathe
....
Nurel (now PeriphaGen) .... Nuron Biotech ... Nutrabiotix
... Nutrient Recovery and
Upcycling .... NuVant
... NuVascular Technologies .... Nuve ..... Nuventix ...
Nuvera
Biosciences ... Nuvera Fuel Cells.. . Nuvotronics ..... Nuvox
Pharma ..... Nu Waves
..... NxThera
... Nvision Biomedical Technologies ..... NZ
Applied Technologies
Oak-Mitsui .... Oasys ...
ObjectVideo
... OBS
Medical ... Ocarina Networks ... Ocata Thera ...
Occipital
....
Ocean Power
Technologies
... Ocean Renewable Power .... Ocera Thera .... OCI ...
Ocugen ..... Ocular
Therapeutix
....
Oculeve
... Oculus ... Oddpost
... Odyssey Systems
Consulting Group ... Oil Chem
Technologies ... OLEDWorks .... Omeros
... OmniGene Bioproducts ... OmniGuide ...
OmniLytics
... Omniox ..... OmniSonics Medical Technologies
... Omnis
PharmaRebiotix .... Omni
Water Solutions ... Onboard Dynamics .... ONCE Innovations
.....
OnChip
Power .... Oncobiologics ..... Oncogenex
... Oncolmmune ..... Oncolinx .... Oncolytics Biotech
...
OncoMed
Pharmaceuticals .... OncoNano Medicine .... Onconova
Therapeutics
...Oncoscope
...
OnCore Biopharma ..... OncoResponse ..... Oncorus .....
OncoSec
Medical
....
Oncothyreon
... Oncovista Innovative Therapies ..... Onduo ..... Onko
Solutions .... ONL
Therapeutics ....
On-Q-ity ....
Ontela ..... On-X Life Technologies ....
Onyx
Pharmaceuticals ... Oorja
Protonics .... Open Algae ... Open Monoclonal Technology
.....
Open Silicon
... OpenWater
Power .... Opertech Bio ..... Opexa
Therapeutics
... OpGen ... OPNET Technologies
... Opsonix .... OptTek
Systems ... Optelecom ...Optelecom-NKF ... Optherion ...
Optical
Concepts .. Optigain .. Optimal Technologies ... Optimus
Technologies .... OptiNose .... Optivision
...
Optofluidics ... OptoLum ..... Optonicus .... Opto Technology
...
Optomec
....
OPX
Biotech
... Oragenics .... OraMerix
... Orasi Medical ... OraSure
Technologies ....
Orbital
Technologies
... Orbotix .... Orchard Therapeutics ..... Orchid
Cellmark
... Oregon Iron
Works .... Orexigen
Therapeutics
... Organic Research .... Organogenesis ...
Organovo
..
ORIC Pharmaceuticals ..... Oricula Therapeutics .... Origin
Medsystems ..... OriginOil
... Orion Energy Systems ... Orion Genomics ...
Ormet
Circuits ... Orologic... Ortel ... OrthoAccel
Technologies ... Ortho Kinematics
.... Oryx Technology ...Oscient Pharamceuticals ...Oscilla
Power
.... Osiris
Therapeutics ... OSI Pharmaceuticals ... Oso Biopharmaceuticals
Manufacturing .... Osprey Medical ....
Ossianix
... Ostendo Technologies ...
Osteotech ... Osterhout Design Group .... OtoNexus Medical
Technologies .... Otonomy .... OtoSense
.... Ottomatika .... Outset Medical .... OvaScience ...
Oxford
Performance Materials ... Oxis International .... Oxygen
Biotherapeutics
P3I ... Pace Packaging .... Pacific Biosciences
.... Padlock Therapeutics .... Pain Therapeutics ...
PaizaBio .... Palantir Technologies .... Palmaz Scientific ..... Palmer
Labs
...
Paloma Pharmaceuticals ... Panacea Solutions ....
Panacos
... Pan Genome Systems .... Panomics
..... PanTheryx .... Paper
Battery ....
PapGene .... Paradigm Diagnostics .... Paradigm
Sensors
... Paragon Dynamics
...
Paragonix Technologies .... Parasol Therapeutics
... Paratek
Pharmaceuticals .... Parexel International .... Parion Sciences
... ParkerVision .... Partpic .... Passport
Systems ... Pasteuria Bioscience ... Pathfinder ...
PathoGenetix
... PathoVax ..... Pathway Genomics .... PatientStream ...
PatientWise ...
Patton Medical Devices ... Patton Surgical .... Pavilion
Technologies ... Pax Streamline ... PaxVax ...
PDI Therapeutics ..... PDL
BioPharma ... Pearl Therapeutics
... Pear Therapeutics ..... PECA Labs
.... Pediatric Bioscience .... Peerless Technologies .... Pegasus
Sustainability Solutions ....
Pelican
Products ..... Pellion
Tech ... Peloton Therapeutics ..... Peninsula
Pharmaceuticals ..... PennAlt Organics ..... Penumbra .....
Peptimed
... Peptilogics .... Peptimmune
... Perceptive Navigation ..... Perceptive Sciences
... Perceptron ....
PercipEnz
Technologies
... Peregrine Semiconductor .... PeriphaGen .... Permeon
Biologics
...
Perosphere .... Perscitus Biosciences ... Perseon .....
Persimmon
Technologies ....
PersonalBee ... Personalis ...... Personal Genome
Diagnostics
.... Pervasis Therapeutics
... Pervasive
.... Petra Pharma ..... Pfenex ...
Pharmacyclics
.... PharmaJet .... PharmAkea Therapeutics ....
Pharmasset
... PharmAthene
... PharmatrophiX .... PhaseBio
Pharmaceuticals .... Phase Bioscience ... PhaseRx ....
Phigenix
..... Phoenix Biotechnology .... Phoenix
Nuclear Labs ...
Phoenix Science .. Phononic
Devices
... Photobit ... Photolitec .....
PhotoMedex
... Photonics
Innovations ... Photon-X ....
PhotoSonix Medical .... PhotoThera
...
Photronics ... Phoundry Pharmaceuticals ....
Phurnace
Software ...
Phylonix
.... Phylos Bioscience ..... Physcient .... Physical
Optics... Physical
Sciences
... PhysioGenix
... PhysioSonics ... PhytoTech ... Picolight ....
Picometrix
... Piedmont Biofuels ....Pika Energy ... Pilus
Energy ....
Pinger
...
Pinnacle Technology ... Pioneer Surgical
Technology .... Pixelligent .... Pixel
Optics .. Pixim ... Pixtronix ... Planar Energy
...
Planar Systems ... Planet Labs .... Plano Microwave ..... Plasan ...
PlasmaTech Biopharmaceuticals .... Platypus
... Play-i
.... PLC
Medical Systems
... Plextronics ... Plexxikon
... Pliant Therapeutics .... Plug
Power ... Pluromed ... PLx Pharma ..... PLX Technology ....
PMT
.... PMV Pharmaceuticals .... PneumRx .....
Point Source .... Polarean ..... Polatis
.... Polychromix
...
Polyera ... PolyMedica ... PolyMedix ... Polymer
Technology
Systems ... Polynoma ..... PolyNova .... PolyPlus ... PolyRemedy ...
Polysciences ... Polystor ... Portola
Pharmaceuticals ...
Possis Medical ... Pothole Pros ... PowerGenix ...
Powerlight
... Power
Precise Solutions ... PowerVision ... Pozen ...
Prairie
Technologies ..... Pranalytica ... Precision Biopsy
...
Precision BioSciences
.... Precision for Medicine .... Precision Genome
Engineering .... Precision Ocular Metrology ..... Precision Optics
...
Precision
Therapeutics (now Helomics) .... Precision Virologics .... Predictive
Biosciences
... Pregmama ..... Presage Biosciences
... Presidio
Pharmaceuticals
.... Pressure BioSciences
... Preventice ..... Prevention Pharmaceuticals ....
Prieto Battery ..... Primera
Biosciences ... Primordial .... Primorigen Biosciences
... Primus Power .... Principia Biopharma ....
Prism
Solar Technologies .... Procept BioRobotics ..... ProCertus
BioPharm
... Proclara Biosciences (formerly
NeuroPhage
Pharmaceuticals) .... Procyrion .... Profectus BioSciences .
.. Progenics
Pharmaceuticals
... Progenity .... Prologic ... Promedior
...
Promega .....
Promentis
.... Pronutria ..... Propeller Health ....
Propulsive Wing
.... ProstaGene ....
Protagonist
Therapeutics .... Protein Foundry ..... Protein Sciences
... ProteinSimple (formerly Cell
Biosciences) .... Proteon Therapeutics
...
Proteostasis
Therapeutics
... Proteotech ... Proteus
Biomedical
... Proteus Digital Health .... Protez Pharmaceuticals
.... Prothena .... ProThera Biologics ...
Proto Labs ... Proton Energy Systems ...Protonex ..
Prototype
Productions .Provagen ... Provenance Biopharmaceuticals
... Proventys
... Provista Diagnostics .... Pryor Medical Devices .....
PsiKick
..... pSivida
... PTC Therapeutics
.... Pulmatrix ... Pulmotect ..... Pulse Electronics ....
PulseTherapeutics ....
PUR
Biologics ..... Pure Bioscience .... Purfresh
... Purillume ..... Pursuit Vascular ... PurThread
.... PvP
Biologics
Qcept Technologies .... Qcue .... QD Vision
...
QED ... qFuzion ..... Qioptiq
... QM Power
... QPixel ... QR Pharma
... QSpex .... Qteros
... QuaDPharma .... Quadra-Aerrow International ...
Quadraspec
...
Quad Technologies .... Qualcomm ... QualityMetric
...
Qualtech Systems ....
Qualtré ... Quanterix
... QuantRx Biomedical
.... Quanttus .... QuantTera .... Quantum Epitaxial
Designs ... Quantum Fuel Systems... Quantum Logic
Devices
... Quantum Materials .... QuantumSphere
.... Quark
Biotech ... Quark
Pharmaceuticals ... Quick–Med
Technologies .... Quid ..... Quidel
... Quincy
Bioscience
... Quintessence Biosciences ... Quorum
Systems
Radant Technologies ... Radiabeam Technologies
... Radiance Technologies .... Radiant Photonics...Radiation
Monitoring Devices
... RadioMedix ... Radius
Health ....
Rafagen ... Rainbow Organic Farms ... RainDance
Technologies
...
RainStorm ...
Rain Water Solutions ... Raland Therapeutics .... RaNA
Therapeutic ...
RAN Biotechnologies .... Range Fuels
... Rapamycin Holdings ..... RaPharmaceuticals
... Rapid Diagnostek ... Rapid
Micro Biosystems
... Rapiscan ... Raser Technologies
.... Raydiance ... Raymond .... Raze Therapeutics
.... RE2
.... Rebellion
Photonics ....
Rebiotix ....
Receptor Logic ...
Receptos
..... Recodagen ...
Recombinetics
... ReconRobotics
.. Recro Pharma .... Redox Power Systems .... Red
Rock
Biofuels .... Redwood
Robotics .... RedZone
Robotics .... RefleXion
Medical .... Regado
Biosciences
... ReGear Life Sciences ..... ReGen
Biologics ... Regenerative
Medical Solutions ..... Regenerative Sciences ... Regenxbio
....
Regulus Therapeutics ... Rehabtics .... ReliantHeart ....
Relievant Medsystems
..... Relypsa .... Remedium
Technologies
...
RemoteReality .... Rempex
Pharmaceuticals .... Renaissance Services ..... Renegade
Materials .... Renewable
Alternatives
... Renewable Energy Group .... Renmatix .....
Renovion
.... Renovis ...
Rentech ... Replidyne
...
Repligen .. Research Frontiers .. Resolve
Therapeutics
... Resolvyx
Pharmaceuticals ... Resonetics ..... Respicardia
... Respira
Therapeutics .... Response Genetics
...
Restoration Robotics .....Restore Medical ... Retectix ..... Retek
...Rethink
Robotics ... Retriever Technology
.... RetroSense Therapeutics ..... Reva Medical
... Revance Therapeutics Pharmaceutical ....
Revegen
... ReVision Optics ....
ReVision
Therapeutics .... Revitope Oncology ..... ReVivo Medical
....
RevMedx .... ReVolt Tech
... Revolution
Medicines .... ReWalk
Robotics (Israel) .... Rexahn
Pharmaceuticals
... Rex Computing ..... RF Code ...
RFMicron
.. RFS Pharma ..... RF Surgical.
.... Rgenix .... Rhenium
Alloys .. Rheumco .... Rhevision
... Rho ... Rhythm Pharmaceuticals ... Rhythmia
Medical
... RiboNova ......
Rib-X
Pharmaceuticals ... Ridgetop
Group ... Rigel Pharmaceuticals .... RightEye ..... RightHand
Robotics .... Rinat
Pharmaceuticals
.... Rinovum Women’s Health ..... Rio Grande Neurosciences .....
RipCode ... Rive Technology
... RJA Dispersions
... R.L. Phillips ... RMH Sciences ...
Robb Surgical
Devices .... Robopsy
...
Robotic FX ... Robotic Technology
... Rockwell Medical ..... Rocky
Research .... Rodin Therapeutics ... Roka Bioscience .....
RoosterBio .... Rosina Food
Products ....
Ross Valve ..... Rotational
Medical .... RotoMetrics ..... Rowbot Systems .... Royole ..... RQx
Pharmaceuticals .... RRE
Solar ....
Rubicon Tech ...
Rubigo Therapeutics .... Rubitection ..... Rubius Therapeutics ....
Rules-Based
Medicine
... Rushford Hypersonic ... Ruud Lighting ..... RxFunction
...
RXi Pharmaceuticals
...
RxMedic .... Rypos
S2 ... Sadasis .... SafeShot .... Saffron
Technology
.... Sage
Electrochromics ... SADAR 3D .... Sage Science ... Sage
Therapeutics ...Sakti3 ... Salarius
Pharmaceuticals .....
Salient Surgical
Technologies
... Salix
Pharmaceuticals ... Salutaris Medical Devices ..... SAM Medical ....
Sancilio
Pharmaceuticals .... Sand 9 .
.. Sandia Biotech .... Sangamo
Biosciences
... Sangart
... Santalis Pharmaceuticals ..... Santarus .... Sanuwave
Health
.... Sapheon .... Sapphire
Energy ....
SARbarcode .... Sarda
Technologies ...
Sarepta Therapeutics .... SatCon
Technology ...
Satori Pharmaceuticals
.... Savara Pharmaceuticals .... Savi ...
SBH
Sciences ...
Scanadu ..... Scholar Rock .... SciClone Pharmaceuticals
... Sciencescape ..... Scientific
Conservation .... Scientific Research ...
Scientific
Solutions ... Scientific Systems ... SciFluor Life Sciences ... Scilex
Pharmaceuticals .... Scinovia ..... Scioderm .... SciQuest ...
Scopic Software
...
Scynexis ...
SD Catalyst
Group ... SDL .. SeaChange ...
Seacoast Science
... Seahawk Biosystems ... Seahorse
Bioscience
... Seaside Therapeutics .... Seattle BioMed .....
Seattle
Genetics
...
Seattle Medical Tech .... Sebacia .... Second Genome ....
Second
Sight Medical
Products ... Securboration ..... Secure
Computing ... Sedia Biosciences ..... Seeo
....Segetis ... Seldon
Labs ... Selecta Biosciences
...
Semiconductor Laser ... SemiProbe ... Semler
Scientific
.... Semnur
Pharmaceuticals .... Semprius ... Semprus
BioSciences .... Sencera International ...
SenesTech .....
SenGenix ....
Senior Scientific ..... Seno Medical
Instruments .... Senomyx
... SensAble Technologies ... Sense .... Sense
Diagnostics
....
Senseonics ..... Sensintel .... Sensiotec ...
Sensors
Unlimited
... SensorTran ... Sentelligence
... Sentient
Technologies ..... SentreHEART ..... Sepracor
... SeprOx .... SeQual Technologies ... Sequella ...
Sequel
Pharmaceuticals .... Sequenom ... Sequenta ...
Sequent
Medical
.... SeraCare Life Sciences ... Seragon
Pharmaceuticals .... Seres Health .... Serenex ... Sermonix
Pharmaceuticals .... Servergy .....
SetPoint Medical .... Seventh Sense Biosystems ...
SGB
Biofuels ..... SGX
Pharmaceuticals ...
Shamrock Energy ... Shape Pharmaceuticals ..... Shape Security ....
Shapeways .... Sharklet
Technologies ..... Sharp Edge Labs ..... Shift Labs ..... Shiloh
Labs ....Shine
Medical Technologies
... Shore
Thing Shellfish .... Si-Bone .... Sicel Technologies ...
SiCortex
... Sideris Pharmaceuticals ..... SI
Diamond Technology .... Sienna Biopharmaceuticals ..... Sierra Energy
..... Sierra Monolithics
... Sierra Nevada ...
Siga Technologies ...
SiGe Semiconductor ... Sigma Labs (NM) .... Sigma
Technologies .... SignalFX (formerly Signal Fuse) ..... Signal Genetics
.... Signature
Genomic Laboratories
... Sila Nanotechnologies .... Silarus Therapeutics
.... Silatronix ..
Silent
Power ... Silicon Biosystems Menarini ..... SiliconBlue
....
Silicon Laboratories ...
Silicon
Mountain
Design .. Silicon Space Technology .... Siluria ...
Silverbrook
... Silverback ..... Silvergate Pharmaceuticals .... Silver
Spring Networks
... Simbol Materials ... Simply Incredible Foods ... SiMPore
...
Simulation
Technology and Applied Research ... Simulution
... Singlera Genomics ..... Singulex ... Sinmat
... SiNode Systems .....
Sintact Medical Systems
..... Sion
Power
... SiOnyx ... Sioux Manufacturing ...
Sirga Advanced
Biopharma .... Sirion Therapeutics ...
Sirna
Therapeutics ... Sirtris Pharmaceuticals ... Sisu Global
Health
..... Sitari Pharma .....
Skybox Imaging ....
Skyline Medical
....
Skyonic
... SLI .. SLIPS Technologies .....
SmartCells
... Smart Modular
Technologies ... SmartSpark Energy Systems ...
Smart
Structures .... Smart Wires ..... Smisson-Cartledge Biomedical ...
Smooth-Stone
...
SNP Bio ..... Socrates Health Solutions .... Soft Machines
....
Soft Robotics ..... SoftSwitching
Technologies
... Soft Tissue
Regeneration ... Soladigm (now View) ..... SolAero
Technologies ..... Solaicx ....
Solais Lighting
....
Solana Surgical ..... SolaranRx ..... SolarBridge
Technologies ... Solar Connection ....
Solaria ...
Solarmer
Energy ...
Solar Power Technologies ... SolarWinds
... Solazyme
... Solexant ... Solexel ... SolFocus ... Soliant
... Solid Biosciences .... Solid Concepts ..... SolidEnergy
....
Solidus Biosciences
..... SolidWorks
... Soliris .... Soliton ..... Solixia
... Solix
Biofuels
... SolMap
Pharmaceuticals ... SoloHealth ... Solomon
Technologies
... Solo Power .... Solstice Biologics .... Soluble Therapeutics ....
Solx ....
Solyndra ... Soma .... SomaLogic .... Somaxon
Pharmaceuticals ....Somna Therapeutics ...
Sonalysts ...
Soneter .... Sonex Aircraft ... Sonitus Medical
... Sonivate ..... SonoSite
... Sonovex .... Sontra Medical ... Sonus
Pharmaceuticals
...
Sophiris
Bio .... Sophono ..... Soraa .... Sorrento Therapeutics ....
Soteira
... Sostena .... Sotera Wireless ... Sound Pharmaceuticals
.....
Sourcefire
... Source MDx
... Southwall Technologies ... Southwest Windpower
...
Space Dev ...
Spaltudaq ... Spansion .... Sparkbuy ..... Spark Therapeutics ....
Sparo Labs .....
Spatial Photonics
...
SPEC ..... Spectra254 .... Spectragenetics .... Spectral Energies .....
Spectral
Systems .....
Spectranetics ...
SpectraWatt ... Spectro Coating ... SpectrumS4 ....
Speech
Tails ... Speer Medical .... Spero Therapeutics ..... Spinal
Modulation ..... Spinal
Restoration
... Spinal Simplicity ..... SpineGuard ...
Spineology
... Spine Wave .. Spintech .... Spin
Transfer
Technologies ....
SpiralGenetics .... Spiration ... Spire
... Spirox (formerly Nasoform) ..... Spoonflower .... Spotfire ... Spot
On Sciences ...
Spredfast
... Spring Bank Pharmaceuticals ... SpringLeaf Therapeutics
... Spyrix ....SQZ Biotech ..... SRL ... Staktek
Holdings
... Standard
Bariatrics ....
STAR
Cryoelectronics
... Starfire ... Startech Environmental
... Startup Circle Pharma .... StarVision
Technologies
.... Stasys Medical ..... SteadyMed Therapeutics ..... Stealth
Therapeutics
...
Stellaray .... Stellar Science .... Stellent ....
Stemagen
... StemBioSys ....
Stem Cell Assurance (Now BioRestorative Therapies) .... StemCells
... Stemcentrx ..... StemCo
Biomedical ... Stemgent ...
Stemina Biomarker
Discovery ... Stemonix ..... Stereotaxis ... Sterling
Semiconductor ..... StimMed ..... Stirling Energy .... Stottler
Henke ... Straight Flight .... Stratagene ... Strata Oncology
..... Stratasys
... Stratatech
... Strategic Response Initiatives .... Stratos
Genomics
... Stromedix .... Strongbridge
Biopharma .....
Sucampo Pharmaceuticals ..... Summit
Technology
.... Sun BioPharma ..... Sun Catalytix
.... Sunesis
Pharmaceuticals
.... SunHealth Solutions ... Suniva ....
Sunovion
Pharmaceuticals
... SunPower ... Sun Power Biodiesel ...
Sunrise
Ridge Algae ....Sunshine Heart .... Suntech ...
Superconductive
Components ... Superconductor Technologies ... SuperDimension ...
SuperFlex ..... SuperPower ... Superprotonic
.... SupraSensor .....
Surefire
Medical
.... Surface
Logix
... Surface Oncology ..... Surgient ...
SurgiQuest
.... Surmet
... SurModics ... Suros Surgical Systems
..... Surrozen .... Sustainable Oils ....
SustainX ... Sutron ..... SutroVax ..... SuturePro
Technologies (now Ceterix) .... SuviCA .... SuVolta ... Suzlon Rotor
... SVS
... SPEC ... Swallow Solutions .... SweetSpot Diabetes Care
... Swift Biosciences .... Syagen Technology
... Symbiomix Therapeutics ..... Symbiont Web
...
Symbotic ...
Symetrix .... Symic Biomedical ..... Symyx
Technologies
... Synack .... Synageva BioPharma ... SynAm Vaccine
....
SynapDx
....
Synaptics ... SynCardia Systems ..,.. Synchroneuron ....
SynchroPET .... Syndax
Pharmaceuticals
... Syndexa Pharmaceuticals .... Synergy Biomedical
....
Synergy Pharma ..... SynGen .... Synlogic ..... Synopsys .... SynSonix
.... Synta
Pharmaceuticals ... Syntax-Brillian ... SyntheMed
... Synthetic Genomics .... SyntheZyme .....
Synthorx ....
Syntimmune ..... Syntrix
Biosystems ....
Syros
Pharmaceuticals .... Sysgain .... Syslogic .... Systagenix Wound
Management .....
Systems and Processes Engineering
SPEC ... Systima Technologies ..... Sytera
T2
Biosystems ... T3D Therapeutics ..... Tabula ... Tactile
Systems
Technology .... TAI Diagnostics ..... Talecris Biotherapeutics
... Taligen Therapeutics
...
Talima Therapeutics ... Tal Medical ... Talon Therapeutics
... Tandem Diabetes Care ...
Tangen Biosciences
..... Tanox ..Tantaline
.... Tarari ... .Targacept ... TargeGen
... Targ-Anox ... Targanta
... Targazyme (formerly)America Stem Cell....
Targeson
... Targeted Genetics ... Targeted Growth
... Taris Biomedical .... Tarveda Therapeutics
..... Tascent .... Tauriga
Sciences
.... Taxa Biotechnologies ..... Taxon
Biosciences .... Taxus
Cardium (formerly Cardium Therapeutics) ... Taylor
Devices ..... TDA
Research .... Tealium ..... TearScience
...
Tech-X .... Techniscan Medical Systems
... Technology
and Devices Int'l ... TechTol Imaging ... TELA Bio .....
Telecardia ...
TeleContinuity ... Telefactor ..... Telemedicine
Up Close operates as DxUpClose ...... Telik ... Templex
Technology... Tenaya Therapeutics ..... Tendril ... Tendyne
Holdings ..... Tensha Therapeutics ...
Tepha
... TeraDiode .... TeraDiscoveries (now Cloud
Pharma) ....
Terapio ... TeraStor ...
Terrabon ...
Terrajoule ... TerraMetrics ... Terumo BCT .... Terus
Technologies .... TESARO ....
TeselaGen
Biotechnology .... Tessera
Technologies ... Tethys BioScience .... Tetra
Discovery
Partners .... Tetragenetics
... TetraLogic Pharmaceuticals ...
Tetraphase
Pharmaceuticals ... TetraVue ... Tezzaron
Semiconductor ....
TGS Knee Innovations
... TG Therapeutics .... Thar Pharma .... Thalchemy ..... The
ExOne .... The Medicines ..... Therabron Therapeutics ..... Theraclone
Sciences
...
Theragenics
.... Therametric Technologies ... Theranos
....
Therion
Biologics ... Thermacore ... Thermage
...
Thermal Gradiant .... Thermal Spray Technologies
....
ThermalTherapeutic Systems
... Thermedical ...
ThermoAura ....
ThermoCeramiX .... ThermoGenesis .... Thermon ... TherOx ....
Thesan
Pharmaceuticals .... Theseus...
Thetis Pharmaceuticals ...
ThingMagic... Third Wave Technologies .. Thoratech
Tech
... Thorley Industries .... ThreeRivers 3D ..... Threshold
Pharmaceuticals ...
ThromboVision .... Thyritope Biosciences
.... Tiax
...
Tibbetts Industries
... Tibion ..... Tilera ...
Tillges
Technologies ... Tioma Therapeutics ..... TissueLink
... Tissue Regeneration Systems .... Titan
Pharmaceuticals .... Titan Spine ..... TJ Technologies .... TLC
Precision Wafer
... Tmunity Therapeutics .... Tobira Therapeutics ....
Tocagen
...
Tokai Pharmaceuticals .... Tolerx .... TomoTherapy
... Tone Tree ..... Topia Technology .... TopicalRemedy ....
Topokine Therapeutics
.... Torax
Medical ...
Total Immersion ... TotipotentRx .... Totus Solutions ....
Tracon
Pharmaceuticals
... TranS1
.... Transatomic Power .... Transcend Medical ...Transcept
Pharmaceuticals
.... TransCorp
..... TransEnterix ... Transgenomic ... Translattice
.....
TransMedics
... Transmeta ... TransMolecular
... Transphorm .....
TransTech
.... TransTech Pharma (now vTv Therapeutics) ... Transzyme
Transzyme Pharma ... Traverse
Biosciences ... Traycer
Diagnostic Systems ..... Trellis
Bioscience
... Trellis Earth Products ...
Trevena
... Trevi Therapeutics ..... Trex Enterprises ... Triad
Semiconductor .... Tri Alpha
Energy ..... Triangle
BioSystems .... Tribogenics
....
Tribologix
.... Trice
Orthopedics .... Tricida ..... Trident Systems ... Trilumina ....
Trimble Navigation
.... Trimeris
... Triquint
Semiconductor ...
Triton Systems ... Trius Therapeutics ...
TriVascular
Technologies .... Trovagene ..... Trubion
Pharmaceuticals ... Tru-D SmartUVC ..... True Diagnostics
....
True Health Diagnostics
.... True North Therapeutics
..... TruTouch Technologies ..... Try Eco ..... Tryton
Medical
... Tularik .... Turtle Mountain
Communications .... TVA Medical
... Twelve .... Twin Star Medical ... Twist
Bioscience
..... Tyrosine
Pharmaceuticals
....
Tyrx
uBiome .... UCAN ... UES
... Ulthera .... UltraCell ... Ultragenyx
....
Ultralife Batteries
...
Ultramet... Ultradian
Diagnostics ..... Ultraviolet Sciences ... Unbounded Robotics
.... Unchained Labs .... UNIAX
... Unica
... Unidym ... UniEnergy Technologies ..... Unified
Nexsys
.... Unilife ..... Uni-Pixel .... Uniqure
.... United
Devices ... United
Therapeutics
... United Therapies ..... Unity Biotechnology .... Universal
Display ... Universal
Robots ..... Universal
Technology .... Unum Therapeutics .... Unwired
Nation ... Uptake Medical
... UQM Technologies ... Urigen Pharmaceuticals
.... US
Nanocorp ... Uroplasty ..... US Bioscience ..... US
Silicones ... UTC Power .... Utilidata ... Utron
.....
UVision360
Vaccinex ..... Vaccinogen .... Vader Systems .....
Vala
Sciences
....Valencell ... Valence Technology .... Validity
Sensors
... Valmont Industries .... Vanda Pharmaceuticals
... Vanguard Space Technologies ..... Vapogenix ..... Vascular
Biogenics (also VBL
Therapeutics) .....
Vascular
Designs ...
Vascular Pathways ... Vascular Pharmaceuticals ....
Vascular Solutions .....
Vasculox .... VasoGenix
Pharmaceuticals ... Vasoptic Medical ..... Vativ
Technologies ... Vaxart ... Vaxess
Technologies ....
VaxGen
...
VaxInnate ... vCalc .... Vecna Tech ...
Vectorlogics
....
Vedanta
Biosciences
.... Veeva Systems .... Veezyon
... VeinAid ... Velano Vascular .... Velicept
Therapeutic
..... Velocimed ...
Velomedix
... Venaxis ..... Vendormate .... Veniti ... Vensun
Pharmaceuticals ....
VentiRx
...
Ventria Bioscience
... Ventrix ..... Ventrus
Biosciences ... Veracode
... Veracyte
... Veran Medical Technologies ..... Verastem
... VeraSun Energy
... Verax
Biomedical ... Verdezyne ... VerinataHealth ...
Verenium ... Vericel (formerly Aastrom Bio) .... Verifica-BG
... Veritas Genetics .....
Vermillion .... Vermont
Composites ...Veros Systems ... Versar .... Versartis ...
Vestagen
Technical
Textiles .... Vestaron .... Vertex
Pharmaceuticals ... VeruTEK Technologies ... Vextec
... VGBioCogCubed .... V-Glass .... VGo
Communications ...
ViaCell
... ViaCyte
.... Viacor
.... Viamet Pharmaceuticals
... ViaSat
... Vical ... Vicarious .... Vicus Technologies .... Vidacare
... View ..... Viking
Therapeutics .... Vion
Pharmaceuticals
... ViraCor Laboratories ... Viracta Therapeutics ..... Viral
Genetics ....
Virdante Pharmaceuticals ...
Virdia
.... Virent Energy Systems ... Viresco Energy
... Virobay .... ViroPharma . .. ViroXis ...
Virtify .
VirtualScopics
.... Virtusa
... Viscardia ..... VisEn Medical ... VisiGen
Biotechnologies
... VisionGate ..... Vision-Sciences ... Vistagen
Therapeutics ... Vistec
Lithography ... Visterra ...
Visualase .... Vitae Pharmaceuticals ..... VitalMedix
... Vital Therapies ...... Vital Vio .... VitaPath Genetics
... Vitriflex .... Vium ..... Vivex Biomedical
.... Vivisimo
.... Vixar
... Vixel ... Vizzario .... Vlingo
... VLST ..... VMware ... Voci Technologies .... Volcano ....
VoltServer ... VORAGO Technologies (previously Silicon
Space Technology) ..... Vorbeck
Materials
... Vor BioPharma ..... Vortex Biosciences ..... Vortex
Medical
... Voxel
.. voxeljet ..... Voyager Therapeutics
.... Vtesse ....
VT
Silicon
.... vTv Therapeutics (formerly TransTech Pharma) ..... VUV Analytics
.... Vuzix .... Vyriad .... Vyrx
Pharmaceuticals ..... VytronUS
WaferGen
Biosystems ...
Wakonda Technologies ... Walker Magnetics Group ...
Waste2Watergy
.... Waveband
..... Wave Computing ..... Waveguide ..... WaveRx ... Weinberg Medical
Physics .... WellStat
Therapeutics .... Whole Biome ..... Whole
Trees
.....
WiBotic .... Wicab ..... WildcatDiscovery .. Willow Garage
...
Wilocity
.... Wilson
Greatbatch
.. Wilson Tool International .... Wilson Wolf Manufacturing
...
WiMax.com ...
Windlift ... WinSanTor .... Wintegra ... WISErg .... Wizbe
Innovations ...
WMR
Biomedical (now Arsenal Medical) ... Wolf Technical
Services ... WoundZoom .... Woven Orthopedic Technologies
....
Wright Materials Research
... Wright Therapy Products ..... W Solar
Group
X4 Pharmaceuticals ..... Xanofi ... Xanthus
Pharmaceuticals
... XBiotech USA ..... X-Body Biosciences
... Xcede Technologies ..... Xcell Biosciences
....
Xcellerex ... XChanger
Companies .... Xencor .... X-energy ..... Xenetic Biosciences ....
Xenex
Disinfection Services .... Xenex
Healthcare Services ... XenoGen Biosystems .... Xenomics
... Xenoport ... Xeris
Pharmaceuticals ... Xetrios Therapeutics .... XF
Technologies .... xG Technology .... Xidex ... Xitronix
... XL
Hybrids ... Xlumena .... Xollai ... Xolve
(formerly
Graphene Solutions)
... Xoma
... XProSciences (now Icagen) ..... X-Ray Optical .... XSunX
...
Xtalic .. Xtent ...Xtreme Power
... XTuit Pharmaceuticals .... Xunlight
Yan Engines ... Yardney Technical Products .... Y-Carbon ... Yulex .... Yumanity Therapeutics .... Yurie
Z ... Zacharon Pharmaceuticals .... ZafGen .... Zavante Therapeutics ..... ZBB Energy ... ZeaChem ... ZeaKal .... Zebra Imaging .... Zebra Medical Vision (Israel) ..... Ze-gen ... ZenBio ... Zenverge ..... Zeo .... Zephyr Technology ... ZeptoMetrix .... ZeroFOX .... Zero Locus .... ZetaRx Biosciences .... Zilker Labs ... Zinc Matrix Power ... Zintera ..... Ziopharm Oncology ... Ziptronix .... Zogenix ... Zosano Pharma ... ZPower ... ZS Genetics ..... zSpace ..... ZS Pharma ... ZSX Medical .... Zumobi ... Zurex Pharma ... Zwitter Technology .... Zyga Technology .... Zygo ... Zymergen ..... ZymoGenetics ... Zynerba Pharmaceuticals ..... Zyomyx ... Zystor Therapeutics ... Zyvex Technologies