Nelson's News

Carl Nelson Consulting

phone 202-841-1914carl@carl-nelson.com SBIR for high tech innovators

Hark,What News?

news and views for entrepreneurs .....as of Jul 19, 2019

Note: Carl Nelson Consulting, Inc is not an investment adviser and may hold a financial interest or client relationship in companies discussed. Looking for older stories? Visit the archives

Leuko (Boston, MA; no SBIR), an MIT-born technology startup developing the first non-invasive white blood cell monitoring device, today announced it has raised $1.8 million in seed financing [company press release, Jul 17, 19]

Pyxis Oncology (Boston, MA; no SBIR), a newly formed immuno-oncology company, launched with a focus on developing a new family of antibody-based immunotherapies derived from novel insights into the biology of the tumor microenvironment. Leaps by Bayer led the Company's USD 22 million Series A financing [joint company press release, Jul 17, 19]

Fulcrum Therapeutics (Cambridge, MA; no SBIR), a clinical-stage biopharmaceutical focused on improving the lives of patients with genetically defined diseases in areas of high unmet medical need, with an initial focus on rare diseases, announced the pricing of its [IPO] with gross proceeds of $72.0 million [company press release, Jul 17, 19]

Longeviti (Cockeysville, MD; no SBIR) raising up to $12.6M , is developing and commercializing implants for use in complex brain surgeries. [Morgan Eichenseh, Baltimore Business Journal, Jul 18, 2019]

The scent of politics and revenge. Trump Says He May Intervene in Huge Pentagon Contract Sought by Amazon. ... For the president to weigh in on the award of a major government contract would be highly unusual, raising questions of improper political influence. [Scott Shane and Karen Weise, New York Times, Jul 19, 19] What relevant and proper contribution could a president make in a contract selection competition within the announced criteria? If he did so, the contract would be tied up for years in the courts, and the DOD would fall even further behind in adapting to the cloud.

scPharmaceuticals (Burlington, MA; no SBIR, founded 2014),up 32% [Jul 17, 19] focused on developing and commercializing products that have the potential to optimize the delivery of infused therapies, advance patient care, and reduce healthcare costs, announced [that] FDA confirmed that it does not believe it will be necessary to conduct additional clinical safety, efficacy, or pharmacology studies as part of scPharmaceuticals' NDA for FUROSCIX. [company press release, Jul 16, 19] total funding $61M [crunchbase.com]

AVROBIO up 20% [Jul 17, 19] announced the pricing of an underwritten public offering [to raise] approximately $120million. [company press release, Jul 16, 19]

Seattle Genetics up 19% [Jul 17, 19]

Xenetic Biosciences down 49% [Jul 17, 19] announced the pricing of an underwritten public offering [to raise] approximately $15 million. [company press release, Jul 17, 19]

The scientists, leaders and investors of Dune Medical Devices (Atlanta, GA; no SBIR, founded 2002 ) [are] working towards eradicating the need for more than one operation to remove cancer from the body—a feat more than 20 companies have been unable to accomplish in the past two decades. The startup, which was founded in Israel in 2004 and later moved its operations to Atlanta, was founded by Dan Hashimshony, who discovered how to differentiate healthy tissue from cancerous tissue using physics and an algorithm. Using the algorithm, Hashimshony developed a pen-like probe that could determine if tissue was cancerous during surgery. [Madison Hogan, AtlInno, Jul 17, 19] total funding $50M [crunchbase.com]

Torque Therapeutics (Cambridge, MA; no SBIR) biotech startup developing immunotherapies for cancers, raised $38.3M in a funding round, according to an SEC filing. [Sri Kalyanaraman, BostInno, Jul 17, 19] earlier announced that [FDA] granted Fast Track designation for Torque’s first Deep-Primed™ T cell immunotherapy program, TRQ-1501 (Deep IL-15 Primed T cells) [company press release, Jun 19, 19]

Black Diamond Therapeutics (Cambridge, MA; no SBIR, founded 2016 in New York) biotech startup developing precision medicines for cancers, raised $44.2M in an $87.2M funding round, according to an SEC filing. [Rowan Walrath, BostInno, Jul 17, 19] prior funding $112M [crunchbase.com]

BioPath Holdings up 33% [Jul 16, 19]

Beta Bionics (Boston, MA; $400K SBIR, founded 2015), a startup using machine learning and artificial intelligence to develop the world’s first autonomous bionic pancreas, closed its Series B and B2 rounds of funding, bringing the company’s total capital to $126M. [Sri Kalyanaraman, BostInno, Jul 16, 19]

Trefoil Therapeutics (San Diego, CA; no SBIR, one $500K NIH grant) announced it raised $28 million in an oversubscribed Series A financing. ... is developing novel engineered fibroblast growth factor-1 proteins (eFGF-1) as a regenerative pharmacologic therapy to treat serious corneal endothelial diseases and epithelial disorders. [company press release, Jun 16, 19] prior funding $5M [crunchbase.com]

Orchestra BioMed (New Hope, PA; no SBIR), a biomedical innovation company providing high-impact solutions for large unmet needs in procedure-based medicine, announced it has completed a $34 million Series B-1 Preferred Stock financing ... Orchestra BioMed’s June 2019 partnership with Terumo included a $30 million up-front payment as well as significant future milestone payments from Terumo and meaningful revenue sharing through sales royalties and exclusive drug formulation supply payments. [company press release, July 10, 19] prior funding $100M [crunchbase.com]

Net loss tariffs. According to data from U.S. Customs and Border Protection, the tariffs President Trump has imposed on Chinese imports have generated $20.8 billion so far, Ana Swanson and Jim Tankersley of The New York Times reported Tuesday. ... But Swanson and Tankersley point out that the president has committed about $28 billion to payments for American farmers hurt by his trade war, leaving a net loss on that basis alone. [Michael Rainey, Financia Times, Jul 16, 19] But have faith, Trump says, "Trade wars are good, and easy to win." and most recently Trump said that there’s still a long way to go to reach a deal with China, threatening to slap tariffs on another $325 billion of Chinese goods. [Yun Li, CNBC, Jul 16, 19]

Capricor Therapeutics (Beverly Hills, CA; $8M SBIR) up 93% [Jul 15, 19] a clinical-stage biotechnology company, announced that a pre-specified interim analysis performed on 6-month data from the HOPE-2 trial showed statistically significant results [for steroid-treated boys and young men who are in advanced stages of Duchenne muscular dystrophy (DMD),across several independent clinical measures. [company press release, Jul 15, 19]

Xenetic Biosciences down 16% [Jul 15, 19]

Eton Pharma {Deer Park, IL; no SBIR) down 16% [Jul 15, 19]

Luminar Technologies said that its new Iris sensors will be ready to launch commercially on production vehicles beginning in 2022, ready to be sold for as little as $500 each. [Cromwell Schubarth, Silicon Valley Business Journal, Jul 11, 2019] acquired subsidiary Black Forest (Colorado Springs, CO; $8M SBIR)

BioMarin Pharmaceutical will file for US and Europe approvals of its hemophilia A gene therapy, known in shorthand as valrox, by the end of the year. [Alex Lash, xconomy.com, Jul 12, 19]

Fulcrum Therapeutics (Cambridge, MA; no SBIR) revealed terms for its proposed IPO, targeting [$70M]. The rare disease drug developer would use the proceeds to run Phase 2b tests of losmapimod, an experimental treatment for facioscapulohumeral muscular dystrophy. [Alex Lash, xconomy.com, Jun 12, 19]

Skyhawk Thera (Waltham, MA; no SBIR) is announcing that pharma giant Merck has stepped up with its own initiative on neurodegeneration while adding cancer to the RNA menu of collaborative specialties at the upstart drug discovery unit for the first time. [John Carroll, Endpoints News, Jul 12, 19]

IGM Biosciences (Mountain View, CA; SBIR) a global leader in [R&D of engineered IgM antibodies for therapeutic use, nnounced the closing of its $102 million Series C financing. [company press release, Jul 12, 19]

The U.S. Department of Energy (DOE) announced more than $24 million in funding for 77 projects through its Technology Commercialization Fund (TCF), which will be matched by funds from the private sector. Third party validtion does have its merits for government "investment."

The investment boom hasn’t happened. “A slim 5% rise in 2019 capital spending is in store, down from last year’s 6% gain,” Kiplinger reported last month. “That is a small annual gain compared with past decades, when double-digit increases in capital spending were relatively common.” The administration didn’t have any magic dust. Economic growth appears to be settling down around the level that Trump disparaged when Obama was president. The new normal is not much different from the old normal. [Steve Chapman, Chicago Tribune, Jul 15, 19] No gain, no matter; Trump got his large personal tax cuts with a smoke screen of economic promises made many times before by supply-side pushers.

Spend same, tax less, grow debt, beg for re-election. The U.S. budget deficit grew 23% in the first nine months of the fiscal year [Jeff Sparshott, WSJ, Jul 12, 19] while Treasury Secretary Mnuchin warned that the federal government could run out of cash sooner than expected [Fiscal Times] Imagine that, the supply-side dream again collapses, repeatedly over its forty years.

Celsius Therapeutics (Cambridge, MA; no SBIR, founded 2018), focused on the discovery and development of precision therapeutics for patients with autoimmune diseases and cancer, announced a collaboration with Janssen Biotech. ... Celsius will apply its proprietary single-cell genomics and machine learning platform to identify predictive biomarkers of response from Janssen’s VEGA study, a Phase 2a clinical trial evaluating the efficacy and safety of combination therapy with guselkumab and golimumab in patients with ulcerative colitis. [company press release, Jul 9, 19] total funding $65M [crunchbase.com]

Infinite Electronics (Irvine, CA; no SBIR), a leading global supplier of electronic components serving the urgent needs of engineers through a family of highly recognized and trusted brands, has announced today its acquisition of Integra Optics (Latham, NY; no SBIR, founded 2007), a leading provider of high-quality optical transceiver products and solutions. [Infinite press releas, Jun 9, 19]

Xi, however, apparently believes he will not be able to realize his outsized ambitions unless he can shut off China while, at the same time, obtaining access to other markets. Beijing and Washington are promoting two irreconcilable visions of that country’s future. [Gordon Chang, Hoover Institution, Jul 11, 19] Meanwhile our Twittering leader says Trade wars are good, and easy to win. And his "base" seems not to mind his cynical exploiation of them.

Immunic (San Diego, CA; no SBIR) up 71% [Jul 10, 19] a clinical-stage biopharmaceutical company developing a pipeline of selective oral immunology therapies aimed at treating chronic inflammatory and autoimmune diseases ... Its subsidiary, Immunic AG, is based in Planegg-Martinsried, Germany, where the company’s research and development activities are conducted. [company website]

Eight years after biotech Prometheus Laboratories (San Diego, CA; $400K SBIR) was acquired by Nestlé Health Science, the diagnostic business has been sold again, this time to a little-known biotech called Precision IBD {San Diego, CA; no SBIR) that plans to lay off approximately a quarter of Prometheus’s workforce. [Sarah de Crescenzo, xconomy.com. Jul 11, 19]

And the winners are ... . Treasury Secretary Steven Mnuchin in recent days urged U.S. suppliers of Huawei Technologies to seek exemptions to resume sales to the blacklisted Chinese firm. [Kate O’Keeffe and William Mauldin and Asa Fitch, Wall Street Jounral, Jul 10, 19] And with no law to ordain criteria, an amoral executive is free to pick whomever he arbitrarily chooses to get a profitable license. What true red-meat free-market Republican would stand for such bribery bait from a Democratic president?

Blue Water Vaccines (Cincinnati, OH; no SBIR), developing a universal flu vaccine, announced the completion of an oversubscribed $7M seed round, FINSMES reports. ... basing its work on that which was originally developed by theoretical epidemiologist Sunetra Gupta and virologist Craig Thompson’s team at the University of Oxford in the U.K. [Courtney Gabrielson, CincyInno, Jul 9, 19]

Lyndra Therapeutics (Watertown, MA; $1.9M SBIR), making daily pills a thing of the past, has announced a partnership with Gilead Sciences to develop and commercialize ultra-long-acting oral HIV therapies. Gilead will have exclusive rights to Lyndra’s therapeutics platform for ultra- long-acting formulations related to HIV. ... partnership announcement comes just months after Gilead joined Lyndra’s oversubscribed $60.9 million Series B financing round [Lyndra press release, Jun 9, 19] Gilead pays startup $123M [Allison DeAngelis, Boston Business Journal, Jul 9, 19]

Xenetic Biosciences down 17% [Jul 8, 19]

biotech TAI Diagnostics (Wauwatosa, WI; no SBIR, founded 2015) recently launched a Series B funding round in hopes of raising $15 million to $20 million, according to CEO Langley. [Andrew Weiland, Milwaukee BizTimes, Jun 5, 19]

Xenetic Biosciences up 39% [Jul 5, 19]

Boston Biomedical (Norwood, MA; $1.6M SBIR) announced that the CanStem111P study evaluating the safety and efficacy of investigational agent napabucasin plus weekly nab-paclitaxel will be discontinued due to futility. [company press release, Jul 1, 19]

Karyopharm Thera (Newton, MA; $1.2M SBIR) up 36% [Jul 3, 19] announced that the [FDA] approved oral XPOVIO(TM) (selinexor), a nuclear export inhibitor, in combination with dexamethasone for the treatment of adult patients with relapsed or refractory multiple myeloma (RRMM) who have received at least four prior therapies and whose disease is refractory to at least two proteasome inhibitors, at least two immunomodulatory agents, and an anti-CD38 monoclonal antibody. [company press release, Jul 2, 19]

Melinta Thera up 18% [Jul 3, 19]

Alycone Lifesciences (Lowell, MA; no SBIR) that optimizes molecular therapy for the brain, raised $2.2M in a $3M funding round, according to an SEC filing. [Sri Kalyanaraman, Boston Inno, Jul 3, 19]

Shine Medical Technologies (Janesville, WI; one SBIR) raised $18 million in new funding, a combination of equity and stock options, according to [SEC] filing The round could reach $30 million, the document shows. ... is developing particle accelerator technology used to produce a crucial medical radioisotope. [Jeff Engel, xconomy.com, Jul 3, 19]

Our [Revolutionary] army manned the air, it rammed the ramparts, it took over the airports, it did everything it had to do, and at Fort McHenry, under the rockets’ red glare, it had nothing but victory. [Donald Trump, July 4, 2019]

CyberOptics down 23% [Jul 2, 19]

Xenetic Bio down 17% [Jul 2, 19]

biotech giant Vertex Pharmaceuticals’ plans to acquire preclinical gene editing startup Exonics Therapeutics (Cambridge, MA; no SBIR, founded 2017) for $245M. [BostonInno, Jul 2, 19] total funding about $45M [crunchbase.com]

The U.S. Army’s new Futures Command is accelerating research into synthetic biotechnology to help the military develop next-generation living camouflage and other never-before-seen organisms and materials. [Patrick Tucker, DefOne, Jul 2, 19]

Adaptive Bio down 17% [Jul 1, 19]

Odylia Therapeutics (non-profit, Boston, MA) is teaming up with PTC Therapeutics (SOUTH PLAINFIELD, NJ; $6M SBIR) to develop novel gene therapies in rare inherited retinal diseases using the Anc80 vector system developed by researchers at Massachusetts Eye and Ear. [Rowan Walrath, Boston Inno, Jul 1, 19]

VC good? The question of whether the venture-capital industry creates any social benefit looms over [the book]. Mr. Nicholas, a professor at Harvard Business School, is evidently a fan of American-style venture capital. “The fact that so many innovations have been launched in this way says a lot about the economic benefits of a vibrant and unconstrained venture capital industry,” he contends. But his book doesn’t demonstrate that venture capital as promoted in the U.S. is the best way, or even a good way, to support risk-taking. [Marc Levinson reviewing Tom Nicholas’s “VC: An American History., Wall Street Journal, Jun 2, 19]

Xenetic Biosciences up 35% [Jun 28, 19]

Karuna Therapeutics (Boston, MA; no SBIR), up 25% [Jun 28, 19] a clinical-stage biopharmaceutical primarily focused on developing novel therapies to address disabling neuropsychiatric conditions, announced the pricing of its upsized [IPO] to raise $89M. [company press release, Jun 28, 19]

drugmaker ImmunoGen (Waltham, MA) announced it will reduce its workforce by approximately 220 employees, after an operational review. [company press release, Jun 27, 19[

Adaptive Bio up 20% [Jun 28, 19]

Chimerix up 19% [Jun 28, 19]

Sarepta Thera up 17% [Jun 28, 19]

Corporate and venture-capital investors are funneling $250 million into startup Century Therapeutics LLC (Philadelphia, PA) to finance an effort to cure cancers through a new type of cellular therapy. ... is using a type of stem cell, called induced pluripotent stem cells, to develop cancer treatments. The approach involves reprogramming a mature cell into a state that enables it to differentiate into any type of cell. [Brian Gormley, Wall Street Journal, Jul 1, 19]

Novavax, which develops vaccines for infectious diseases, announced yesterday that it's selling its manufacturing business to Catalent Biologics’ Baltimore-based Paragon Gene Therapy unit. The $18M deal will transfer leases of two product development and manufacturing facilities, sell off the equipment and transfer more than 100 Gaithersburg employees. For Novavax, the move frees up cash to advance its NanoFlu and ResVax products through clinical development and regulatory review, according to the company. [DCInno, Jun 28, 19]

Atossa Genetics up 16% [Jun 26, 19]

Boom and bust 1990s redux. Adaptive Biotechnologies (Seattle) [up 102% [Jun 27, 19] just raised $300 million. BridgeBio Pharma (Palo Alto, CA) has topped it, raising $348.5 million. .... BUT SVB Leerink analyst Geoffrey Porges sees a few warning signs, like a drop in financing across the biotech sector. He also notes that just over half (53 percent) of the biotechs that have gone public during this super-cycle have disappointed investors, with annualized eturns of negative 10 percent or worse. [Alex Lash, xconomy.com, Jun 27, 19]

Mirati Therapeutics (San Diego, CA; no SBIR, founded 2013, IPO 2013) plans to raise more than $200 million this week in a public offering. ... Mirati’s sitravatinib is an experimental treatment for patients with non-small-cell lung cancer (NSCLC). [Sarah de Crescenzo, xconomy.com, Jun 26, 19]

PanTheryx (Boulder, CO; no SBIR, founded 2007) CEO Mark Braman says the [first mother's milk] fluid’s components can also help resolve gastrointestinal disorders rooted in the gut microbiome. Now, the company has $50 million in new capital to ramp up its research. [Frank Vinluan, xconomy.com, Jun 26, 19] prior funding $88M [crunchbase.com]

Myriad Genetics up 17% [Jun 26, 19]

OncoCyte down 37% [Jun 26, 19]

Startup Encoded Therapeutics (South San Francisco, CA; no SBIR) raised $104 million to join the race to expand gene therapy’s reach. .... has emerged from the startup accelerator of Illumina. ... brings its total funding to $158 million and will back human tests of a gene therapy for a rare form of epilepsy called Dravet syndrome. [Ben Fidler, xconomy.com, Jun 26, 19]

ProThera Biologics (East Providence,RI; $11M prior SBIR) that works to develop proteins for the therapeutic treatment of life-threatening inflammatory conditions, received a $2.03 million [NIH SBIR] towards the company’s study of a new prognosis assessment test. This test would determine which infants “who have, or might develop, sepsis and necrotizing enterocolitis,” and a result, which infants would require a specific treatment. [Courtney Gabrielson, RhodeIsland Inno, June 25, 19]

ImmusanT (Cambridge, MA; no SBIR, founded 2011) a clinical stage company leveraging its Epitope-Specific Immuno-Therapy™(ESIT™) platform to deliver first-in-class peptide-based immunomodulatory vaccinetherapies to patients with autoimmunediseases,has discontinued thePhase 2 global study for its lead candidate,Nexvax2®, intended as a treatment forceliac disease. The results from aninterim analysis revealed Nexvax2 did not provide statistically meaningful protection from gluten exposure for celiac disease patients when compared with placebo. [company press release, Jun 25, 19] total funding $73M [crunchbase.com]

Frontier Medicines (South San Francisco, CA; no SBIR) launched with $67 million and a mission to find drug-binding pockets on previously undruggable proteins. ... described itself as being the preclinical stage and said it would develop drugs for debilitating diseases, starting with cancers. [Alaric DeArment, MedCity News, Jun 26, 19]

InterVene (South San Francisco, CA ; no SBIR, founded 2011) secured $15 million to validate its catheter-based treatment for correcting failed one-way valves in the veins of the legs, which can lead to backflows of blood, pain and swelling. [Conor Hale, Fierce Biotech, Jun 25, 19] prior funding $21M [crunchbase.com]

Toyon Research (Goleta, CA; 424 SBIR awards for about $130M from DOD 1986-2018) was one of Four companies have received five-year, cost-plus-fixed-fee contracts worth $49.8M combined to help the U.S. Navy develop, test and deploy intelligence, surveillance, reconnaissance and targeting platforms. [Jane Edwards, GovConWire, Jun 26, 19] latest listed award Person-Centered Planning ToolKit: Development of an Application to Improve Workforce Participation Through Team Collaboration and Customized Employment Discovery Technology. In nature and government, every new species triggers the rise of species specializing in feeding on it.

Chinese President Xi Jinping plans to present President Trump with a set of terms the U.S. should meet before Beijing is ready to settle a market-rattling trade confrontation, raising questions of whether the two leaders will agree to relaunch talks, Lingling Wei and Bob Davis report. Beijing is insisting the U.S. remove its ban on the sale of U.S. technology to Chinese telecommunications giant Huawei and wants the U.S. to lift all punitive tariffs. Officials also want Washington to drop efforts to get China to buy even more U.S. exports than discussed when the two leaders last met in December. [Jeff Sparshott, Wall Street Journal, Jun 26, 19] The challenge for both sides is a mercurial tariff-lover running for re-election who wants arbitrary authority to dictate trade terms. After all, the other side's leader has that kind of arbitrary authority.

Acer Thrapeutics (Newton, MA; no SBIR) down 79% [Jun 25, 19] focused on the acquisition, development and commercialization of therapies for serious rare and life-threatening diseases with significant unmet medical needs, announced it has received a Complete Response Letter (CRL) from [FDA] regarding its New Drug Application (NDA) for EDSIVO(TM) for the treatment of vascular Ehlers-Danlos syndrome (vEDS). The CRL states that it will be necessary to conduct an adequate and well-controlled trial to determine whether celiprolol reduces the risk of clinical events in patients with vEDS. Acer plans to request a meeting to discuss the FDA's response. [company press release, Jun 25, 19]

Immunic down 26% [Jun 25, 19]

CEL-SCI down 17% [Jun 25, 19]

Applied Research Associates (Albuquerque, NM; about $20M SBIR) was one of five entities who won spots on a potential six-year, $100M other transaction agreement to develop expeditionary warfare technology protoypes for the Naval Sea Systems Command. [Brenda Marie Rivers, GovConWire, Jun 26, 19]

Avisa Pharma (Santa Fe, NM; no SBIR, founded 2010) biotech startup raises millions ahead of product launch [Collin Krabbe, Albuquerque Business Journal, Jun 25, 19] Developer of a rapid, point-of-care breath test for the diagnosis of pulmonary infections designed to aid clinical decision making on use and choice of antibiotics. prior funding $7M [pitchbook.com]

SomaDetect (Buffalo, NY; no SBIR), a past 43North champion, has received a $500,000 investment from the Western New York Impact Investment Fund. [Matt Glynn, The Buffalo News, Jun 25, 19]

Immunic (San Diego, CA; no SBIR), up 91% [Jun 24, 19] clinical-stage biopharm focused on developing potentially best-in-class, oral therapies for the treatment of chronic inflammatory and autoimmune diseases, announced that [it] will present previously unpublished data regarding the company's lead program, IMU-838, at the GI Inflammatory Diseases Summit (GIIDS). [company press release, Jun 24, 19]

Krystal Biotech (Pittsburgh, PA; no SBIR) up 41% [Jun 24, 19] announced that it has priced the previously announced underwritten public offering [to raise $100M] [company press release, Jun 24, 19]

Minerva Neurosciences (Waltham MA; no SBIR) up 40% [Jun 24, 19] focused on the development of therapies to treat central nervous system (CNS) disorders, announced results of a clinical trial (ISM2005) of seltorexant (MIN-202) in patients with insomnia disorder that demonstrated highly statistically significant (p <=0.001) and clinically meaningful improvement on LPS at Night 1, the primary endpoint of the study. The mean decrease from baseline at Night 1 in LPS was 15 minutes for placebo, 30 minutes for seltorexant 5 mg, 50 minutes for seltorexant 10 mg, and 48 minutes for seltorexant 20 mg. [company press release, Jun 24, 19]

RE2 Robotics (Pittsburgh PA; no SBIR says SBA database), a leading developer of robotic manipulation systems, announced that the company was awarded an [Army] Phase III SBIR grant from the Army and the U.S. Army Medical Research Acquisition Activity (USAMRAA) to continue the development of its LIFELINE system, which is designed to assist combat medics in the field. [company press release, Jun 24, 19] Note: Phase III is SBIR in name only, no SBIR money, just a competitive edge for sole-source follow-on work. Also got $2.9M AF SBIR in 2018, a Phase II Navy SBIR and a Phase II Army in 2017, $1M Phase II in 2016, a Phase II Army in 2012, and of course a Phase I SBIR contract before every Phase II [data from company website]. Warning: do not trust SBA database for accurate SBIR award info.

OncoCyte up 19% [Jun 21, 19]

AMAG Pharma up 15% [Jun 21, 19] [FDA] approved a drug to treat low libido in women, and shares of the company slated to market the medication, ... AMAG licensed Vyleesi from Palatin Technologies Inc. PTN, +4.69% and under the terms of their agreement the FDA approval triggers a $60 million payment to Palatin, plus tiered royalties tied to sales milestones. [Claudia Assis, Market Watch, Jun 21, 19]

Axial Biotherapeutics (Waltham, MA; no SBIR) announced a direct investment of $10M to fund the discovery and development of novel gut-targeted, small molecule approaches in oncology [Rowan Walrath, BostonInno, Jun 21, 19]

Tangen Biosciences (Branford, CT; $400K SBIR, founded 2013), developers of cheap and portable molecular diagnostics for outside the lab, announced that it has closed a $9 million Series A equity round [company press release, Jun 20, 19] prior funding $2M [crunchbase.com]

Platelet BioGenesis (Harvard spinout, Chestnut Hill, MA; $2M SBIR, founded 2014), startup that uses a bioreactor to create platelets, raised $11.4M in a funding round, according to an SEC filing [Sri Kalyanaraman, BostonInno, Jun 21, 19] private funding $1M [crunchbase.com]

Acutus Medical (Carlsbad, CA; no SBIR, founded 2011) announced a $170 million financing, including a $100 million Series D equity financing and a $70 million credit facility. The funding is intended to accelerate commercialization and facilitate global business development activities as the company continues to transform arrhythmia care through distinct, innovative technologies designed to provide physicians and patients with improved results. [company press release, Jun 20, 19] prior funding $208M [crunchbase.om]

The lion’s share of the U.S. drone fleet is easy prey for advanced air defenses. “Current generation drones simply can’t operate effectively in contested airspace. [Patrick Tucker, Defense One, Jun 20, 19] But the Mississippi Congressional delegation forced the Navy to spend a decent part of its money on building ships the Navy didn't want.

Cat's away, mice can play. The Trump administration has found a way to deregulate: don't hire people to enforce the rules. [Jeff Sparshott, WSJ, Jun 24] That attitude of arbitrary failure to "faithfully execute" could spread to programs like SBIR unless and until Congress steps in.

Peers v users. NIH awards are much less concentrated than those awarded by the DoD. Firms receiving at least 10 awards during the 10-year period received more than half (51 percent) of all DoD SBIR/STTR awards from 2008 to 2017, while similar firms received just 11.6 percent of NIH SBIR/STTR awards, according to an SSTI analysis. The total size of NIH SBIR/STTR awards, the relative lack of concentration, and the availability of plentiful proposal data make the agency ideal for the following Useful Stats analysis. [Jonathan Dworin, SSTI, Jan,, 3, 19] The effect of NIH peer review versus DOD user review. Users fund what they intend to use or would make government smarter.

SBIR success rates 2008-2017 published by SSTI - a misleading but easy to collect figure. A low success rate means that the agency is not clarifyng the realities of what succeeds, and a lot of useless work by hopeful proposers for free money. It's all a natural consequnence of Congress's inventing a handout program for a favored constituency with no oversight on efficiency for all concerned. And, no, there is no prospect for fixing the problem. Read the analysis .

CEL-SCI up 15% [Jun 20, 19]

Diamedica Thera up 30% [Jun 20, 19] announced that DM199 (recombinant KLK1) was observed to be safe and well tolerated with no drug-related serious adverse events (SAEs), consistent with earlier DM199 studies in healthy volunteers. [company press release, Jun 19, 19]

Gilead Sciences and Nurix Therapeutics (San Francisco, CA; one SBIR) discovering drugs that harness the body’s natural process to control protein levels, announced a global strategic collaboration to discover, develop and commercialize a pipeline of innovative targeted protein degradation drugs for patients with cancer and other challenging diseases. [joint companies press release, Jun 19, 19] Nurix's NIH SBIR was College Alcohol Assessment and Intervention Training Simulation, a redux of NIH's famous early SBIR for a Smoke-enders Video. Ah well, Congress gave them unliateral authority to decide what constitutes investment quality innovation.

Prevail Therapeutics (New York, NY; no SBIR) announced the pricing of its [IPO] to raise $125 million [company press relese, Jun 19, 19] developing disease-modifying gene therapies to prevail against neurodegenerative diseases [company website]

Vuzix up 19% [Jun 20, 19]

Genocea Bio down 25% [Jun 19, 19] announced the pricing of a public offering at $3.50 per share [company press release, Jun 19, 19]

Stoke Therapeutics (Boston, MA; no SBIR, founded 2014) is the latest biotech company to debut on Wall Street, raising $142 million to test an experimental therapy for a rare form of epilepsy. Stoke does not yet have any human data to show investors, but the Bedford, MA, company was still able to sell more shares than it planned—and at a higher price. [xconomy.com, Jun 19, 19] prior funding $130M [crunchbase.com]

Pyran LLC (Madison, WI; $200K SBIR) received a $120,000 investment from new angel investor group. ... makes a compound that can be used to make environmentally-friendly paint and plastic chemicals [that] was developed by University of Wisconsin student Kevin Barnett and his professor, George Huber, with a three-year, $3.3 million U.S. Department of Energy grant. The technology, which uses catalytic engineering to convert a feedstock derived from corncobs. [Molly Dill, Milwaukee BizTimes, Jun 18, 19] The federal agencies missed the Trumpian directive that the energy answer is coal and oil.

Nimble Therapeutics (Madison, WI; no SBIR, spun off from Roche (Swiss)) raised a $10 million Series A round from three investors [to] to commercialize a “proprietary chemical synthesis technology for drug discovery and development” that was developed by a team led by Jigar Patel at Roche. [Molly Dill, Milwaukee BizTimes, Apr 30, 19]

Great North Labs, (St. Cloud and Minneapolis) closed a $23.7 million fund that it will use to grow its portfolio of Upper Midwest startups. [Alex Wittenberg, Minneapolis / St. Paul Business Journal, Jun 19, 2019]

G1 Thera (Research Triangle Park, NC; no SBIR, founded 2008) up 24% [Jun 18, 19] announced preliminary overall survival (OS) results from a randomized Phase 2 trial which demonstrated that women with metastatic triple-negative breast cancer (mTNBC) lived significantly longer when receiving trilaciclib and chemotherapy compared with women receiving chemotherapy alone. Detailed data from this trial will be presented at a medical meeting later this year. [company press release, Jun 18, 19]

Oncternal Therapeutics up 24% [Jun 18, 19]

Viela Bio (Gaithersburg, MD; SBIR) closed on $75M of funding, for a total haul of $350M since launching 16 months ago. ... in late May, Viela sealed a deal worth up to $220M with Chinese company Hansoh Pharmaceutical Group to commercialize inebilizumab in China. [DCInno, Jun 18, 19]

Kura Oncology (San iego, CA; no SBIR, founded 2014), a clinical-stage biopharmaceutical focused on the development of precision medicines for oncology, announced the pricing of stock shares to rise $100M [company press release, Jun 18, 19] prior funding $60M; claims the knowledge and tools to create targeted treatments and companion diagnostics to identify those patients most likely to benefit. [crunchbase.com]

Arcadia Biosciences raised $6.9M, to invest in hemp research and commercialize its low-gluten and high-fiber GoodWheat product. [Mark Anderson, Sacramento Business Journal, Jun 18, 19]

Cree's Wolfspeed division makes chips out of silicon carbide, which means they can manage high-voltage power distribution without overheating, notes Eric Marshall, a portfolio manager [Michel Brush, MarktWatc, Jun 18, 19] Cree's early work in the early 1990s on conquering defects in silicon carbide was funded by SBIR from BMDO (now MDA) and ONR (Navy research).

Array BioPharma (Boulder, CO; no SBIR) up 57% [Jun 17, 19] Pfizer and Array BioPharma announced that they have entered into a definitive merger agreement under which Pfizer will acquire Array, a commercial stage biopharmaceutical company focused on the discovery, development and commercialization of targeted small molecule medicines to treat cancer and other diseases of high unmet need. Pfizer has agreed to acquire Array for $48 per share in cash, for a total enterprise value of approximately $11.4 billion. [joint companies press release, Jun 17, 19]

biotech startup Comet Therapeutics (Cambridge, MA; SBIR) raised $14.1M in a funding round, according to an SEC filing. [Sri) Kalyanaraman, BostonInno, Jun 17, 19]

Diamedica Therapeutics (Minneapolis, MN; no SBIR) up 19% [Jun 17, 19]

Precipio (New Haven, CT; no SBIR) down 21% [Jun 17, 19]

Ten years after spinning out from Fred Hutch, Adaptive Biotechnologies (Seattle, WA; $4.5M SBIR) is planning a $200 million IPO to help power its diagnostic sequencing tests aimed at the body’s immune system and the scores of related therapies. [Conor Hale, Fierce Biotech, Jun 17, 19]

Orchestra BioMed (New Hope, PA; no SBIR), providing high-impact solutions for large unmet needs in procedure-based medicine, announced it has formed a global strategic partnership with Terumo Corporation (Japan), one of the world’s leading medical device manufacturers, for development and commercialization of Virtue® Sirolimus-Eluting Balloon (SEB), one of its lead assets, in the percutaneous coronary and peripheral interventions field. ... Terumo will make a one-time, up-front payment of $30 million and an equity commitment of $5 million to Orchestra BioMed. Terumo will also make substantial future clinical and regulatory milestone payments to Orchestra BioMed. [Orchestra press release, Jun 13, 19]

U.S. businesses beg to be left off Trump's tariff list. [Reuters, Jun 17, 19] Corruption invited when executive has arbitrary power to award favors. Rule-of-law would specify conditions and criteria for imposition and exemption of such favors as trade tariffs. But Republican Senate too terrified of reaction by Trump "base" to reining in their hero.

Bluebird Bio, which just won approval of Zynteglo in Europe two weeks ago, announced the latest price tag [$1.8M] for a gene therapy, a treatment meant to provide a long-lasting effect with a single dose, developed for the rare blood disease beta thalassemia, [Frank Vinluan, xconomy.com, Jun 14, 19]

Catalyst Pharmaceuticals (Coral Gables, FL; no SBIR), which markets amifampridine (Firdapse) for the autoimmune disorder Lambert-Eaton myasthenic syndrome, sued the FDA claiming the agency’s approval of a rival drug from Jacobus Pharmaceutical (Princeton, NJ; $2M SBIR) violates its drug’s marketing exclusivity. [company press release, Jun 12, 19]

small-molecule therapeutics developer Morphic Holding (Waltham MA; no SBIR) is planning to raise $75M in an IPO [Rowan Walrath, BostonInno, Jun 13, 19]

deciBel Research (Huntsville, AL; $10M SBIR) won a potential 60-month, $172.6M contract to help the Missile Defense Agency develop software and model applications to support ballistic missile defense system operations. [Brenda Marie Rivers, GovConWire, Jun 17, 19] Military software makes useful R&D and sometimes build government confidence in a contractor, especially one near the flagpole. Which gets the gov R&D done with little chance of technical failure, but opens few windows for innovation with long range consequences. It all comes from Congress's wish to help small biz without annual appropriations wrestling.

Pivot Bio (Emeryville, CA; $150K SBIR) believes it can convince farmers to swap out nitrogen fertilizer in favor of specially-fermented soil bacteria that can fuel crop growth organically, without the waste and ecological hazard of traditional methods. The eight-year-old company is armed with more tha n $86 million in financing from the likes of the Gates Foundation, DARPA, and Breakthrough Energy Ventures. [Andrew Zaleski, onezero.medium.com, Jun 13, 19]

Tell whom what? Multiple administration officials also told the [New York Times] that they do not believe Trump was briefed about the plans to deploy computer code into Russia's grid. Some officials within the Pentagon and intelligence community told the Times that there was hesitation to give Trump details about the operations. [Justin Wise, The Hill, Jun 16, 19]

CEL-SCI up 20% [Jun 13, 19]

Ocular Therapeutix up 18% [Jun 13, 19]

Savara (Austin TX; $4.5M SBIR, founded 2007) down 75% [Jun 13, 19], an orphan lung disease company, announced top line data from IMPALA, a pivotal Phase 3 clinical study evaluating Molgradex, an inhaled formulation of recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF), for the treatment of aPAP. [company press release, Jun 12, 19] total funding $101M [crunchbase.com]

Arcadia Biosciences down 32% [Jun 12, 19] announced that it entered into definitive agreements with several institutional and accredited investors for the purchase of its common stock [company press release, Jun 12, 19]

Synlogic (Cambridge, MA; no SBIR) up 25% [Jun 12, 19] a clinical-stage company applying synthetic biology to beneficial microbes to develop novel, living medicines and Ginkgo Bioworks, the organism company, announced a platform collaboration to accelerate expansion and development of Synlogic's pipeline of Synthetic Biotic medicines using Ginkgo's cell programming platform. The agreement provides an $80.0 million equity investment at a premium in Synlogic by Ginkgo and entry into a long-term strategic platform collaboration. Synlogic will use Ginkgo's cell programming platform for building and testing thousands of microbial strains to accelerate progression of early preclinical leads to drug candidates optimized for further clinical development. [company press release, Jun 11, 19]

Arcadia Biosciences up 20% [Jun 12, 19]

Tocagen up 16% [Jun 12, 19]

Oncternal Therapeutics (San Diego, CA, no SBIR, founded 2013) down 17% [Jun 12, 19] Goes Public After Reverse Merger With GTx. Oncternal is in the midst of early-stage testing of its lead drug candidate, cirmtuzumab, which is being studied in combination with AbbVie’s (NYSE: ABBV) cancer drug ibrutinib (Imbruvica) for the treatment of chronic lymphocytic leukemia and mantle cell lymphoma. [Sarah de Crescenzo, xconomy.com, Jun 12, 19) total funding $53M [crunchbase.com]

Stem-cell technology developer InGeneron (Houston, TX; no SBIR) added another $23 million to a Series D financing it announced in 2017, bringing the total of the funding round to $43 million for a clinical study in rotator cuff tendinopathy, a swelling of the tendons and muscles that support the shoulder joint. [David Holley, xconomy.com, Jun 11, 19]

Our age seems to share the skepticism voiced by the German philosopher G W F Hegel (1770-1831) when he said that the only lesson history teaches us is that nobody ever learned anything from history. [Terry Pinkard, Aeon, Jun 12, 19]

Vuzix up 23% [Jun 11, 19]

Ocular Therapeutix up 20% [Jun 11, 19]

Zynerba Pharma up 17% [Jun 11, 19]

CymaBay Thera down 45 % [Jun 11, 19]

Crinetics Pharma down 15% [Jun 11, 19]

Skin microbiome therapeutics company DermBiont (Boston, MA; no SBIR), raised $8.8M in a funding round, according to an SEC filing. [Rowan Walrath, Boston Inno, Jun 11, 19]

Chanel invested in biotech Evolved By Nature (Boston, MA; no SBIR) which has developed liquid silk. No financial terms were disclosed. [Sri Kalyanaraman, Boston Inno, Jun 11, 19]

AeroVironment purchased Pulse Aerospace (Lawrence, KS; no SBIR) for $25.7M in cash to expand its line of small unmanned aircraft systems. [Jane Edwards, GovConWire, Jun 11, 19]

Mapp Biopharmaceutical (San Diego, CA; much government support, founded 2013) announced that it has been awarded an advanced (R&D] contract for $16.5 million with options for an additional $30.0 million by the [HHS's] Biomedical Advanced Research and Development Authority (BARDA), to advance MBP091 though the completion of a Phase 1 clinical trial. MBP091 is a single human monoclonal antibody (mAb) that is being developed as a pan-Marburg virus therapeutic for the treatment of hemorrhagic fevers caused by Marburg and the closely related Ravn virus. [company press release, Jun 11, 19]

Shrinking capital. As some U.S. startups reject their money, Chinese venture-capital firms in the U.S. are dialing back investments, structuring deals to avoid regulators or shutting down local offices. Some complain the U.S. government is going too far .... Chinese investors were once embraced in Silicon Valley both for their pocketbooks and their access to one of the world’s largest and trickiest markets. [Rolfe Winkler, Wall Street Journal, Jun 11, 19] A consequence of Trump's America Alone.

It seemed good politics. The Wisconsin group that negotiated $3 billion in tax incentives for Foxconn Technology Group has problematic oversight practices, a state audit has found, highlighting fresh concerns about the costly incentives states use to attract economic growth. [Shayndi Raice, Wall Street Journal, Jun 11, 19]

CEL-SCI up 22% [Jun 10, 19]

La Jolla Pharma down 17% [Jun 10, 19]

Cymabay (Newark, CA; no SBIR, founded 1991) reported interim results from a Phase 2 study of its experimental drug seladelpar in 181 NASH patients. After 12 weeks of treatment, seladelpar led to “minimal and not significant” reductions in patients’ liver fat compared to placebo—the study’s main goal. [Ben Fidler, xconomy.com, Jun 11, 19] total funding $180M [crunchbase.com]

The Michigan Translational Research and Commercialization (MTRAC) Advanced Applied Materials Innovation Hub at Michigan Technological University recently awarded a combined $302,000 in funding to four projects from researchers across the state. [all at Michigan universities] [MTRAC press release, May 29, 19]

Artizan (New Haven, CT, no SBIR, founded 2016) aims to turn its research about disease-causing microbes into a pipeline of new microbiome drugs. ...announced it completed a Series A round, bringing its total venture capital haul to $12 million. [CEO] Rosen says his company could start human testing within two years. [Frank Vinluan, xconomy.com, Jun 10, 19] prior funding $3m [crunchbase.com]

Cancer immunotherapy leader Merck continued to roll up oncology assets with a deal this morning to acquire Tilos Therapeutics (Lexington, MA; no SBIR, founded 2016). Merck didn’t disclose how much it will pay up front for Tilos, a startup developing drugs for cancer, fibrosis, and autoimmune diseases. But the overall payout could reach $773 million for Tilos shareholders [Frank Vinluan, xconomy.com, Jun 10, 19] prior funding $3M [crunchbase.com]

La Jolla Pharma up 26% [Jun 7, 19]

Vertex Pharmaceuticals ($1M SBIR) is committing $420 million in a pair of deals that expand the company’s research scope to experimental genetic treatments for two forms of muscular dystrophy. Vertex announced that it reached an agreement to pay $245 million up front to acquire Exonics Therapeutics (Watertown, MA; no SBIR, prior funding $45M [crunchbase.com]), using gene editing techniques to develop a treatment for Duchenne muscular dystrophy and myotonic dystrophy type 1. Vertex also said it is paying CRISPR Therapeutics (Swiss) $175 M to expand an existing research collaboration to include Duchenne and myotonic dystrophy type 1. [Frank Vinluan, xconomy.com, Jun 7, 19]

A push to capitalize on potential gene-editing cures is helping early-stage firms draw heavy interest from investors and acquirers.[Wall Street Journal, Jun 8, 19]

La Jolla Pharma up 92% [Jun 6, 19]

American Superconductor down 18% [Jun 6, 19]

biotech LexaGene (Beverly, MA; no SBIR) placed its first beta prototype into Massachusetts Veterinary Referral Hospital in Woburn. [Sri Kalyanaraman, BostonInno, Jun 7, 19]

biotech Arsenal Medical (Watertown, MA; $1.8M SBIR) raised just over $6M according to an SEC filing. [Rowan Walrath, BostonInno, Jun 7, 19]

ChemoCentryx down 19% [Jun 5, 19]

nanotech manufacturer NANO-C (Westwood, MA; $1.2M SBIR) raised $4.8M in a $9M funding round, according to an SEC filing. [Boston Inno.com, Jun 5, 19]

Lung Therapeutics (Austin, TX; one SBIR, founded 2013) raised a $36 million Series C round to take a treatment for a serious complication of pneumonia through phase 2 studies. [ Nick Paul Taylor, Fierce Biotech, Jun 5, 19] prior funding $14M [crunchbase.com]

Another fake exposed. a new [IMF] research paper says there is still no consensus on whether that [gleefully promisd] investment boost has in fact occurred. Outgoing White House economic adviser Kevin Hassett has linked better-than-expected GDP growth to a rise in business investment spurred by the tax cuts, but many analysts outside the Trump administration say the evidence is weak to nonexistent. [Yuval Rosenberg and Michael Rainey, Fiscal Times, Jun 5, 19] Trump and rich supporters got their taxes cut; the people in the street got nothing. Vote Republican if you want to keep those promise-makers in office.

The proposed census changes have a similar goal: If you’re losing in the game of numbers, change the way you count. [Charles Blow, NYTimes, Jun 5,19] Stalin said: It's not who votes, it's who counts the votes.

CEL-SCI up 26% [Jun 4, 19]

Macrogenics down 17% [Jun 4, 19]

Bayer (Germany) is committing $115 million to Arvinas (New Haven, CT; $1M SBIR) in a partnership focused on turning the biotech’s technology for getting rid of harmful proteins into new products for both human health and agriculture. [Bayer] will pay Arvinas more than $60 million. ... Arvinas could earn more than $685 million in milestone payments [Frank Vinluan, xconomy.com, Jun 4, 19]

Bluebird Bio said that the European Commission’s regulatory nod for its therapy, Zynteglo, is a conditional approval, meaning the decision was made with less data than typically required for new drugs. [Frank Vinluan, xconomy.com, Jun 3. 19]

NextCure (Beltsville, MD; SBIR) filed to go public three years after its founding, with a cancer-fighting drug in clinical testing and several local biotech veterans leading the charge. The startup projects $66 million to $77 million in net proceeds from the IPO. [DCInno, Jun 4, 19]

ARCA Bio up 27% [Jun 2, 19]

Genocea Bio up 20% [Jun 2, 19]

Aduro Biotech down 40% [Jun 2, 19] announced the presentation of data from an ongoing Phase 1b clinical trial in collaboration with Novartis. [company press release, Jun 2, 19]

Five Prime Thera down 19% [Jun 2, 19] presented monotherapy data from the dose escalation portion of the Phase 1a/1b clinical trial of FPA150 in patients with advanced solid tumors. [company press release, Jun 1, 19]

Zynerba Pharma down 15% [Jun 2, 19]

Neuralstem (Germantown, MD; $1.8M SBIR) received notice that it could be delisted from the Nasdaq after failing to elevate its stock price consistently above $1 over the past six months. [Washington Business Journal, Jun 2, 19]

Genocea Bio up 25% [May 31, 19]

XBioTek down 21% [May 31, 19]

Merrimack Pharmaceuticals (Cambridge, MA; SBIR) is closing up shop and, over the next two months, will lay off its remaining 27 employees, [said] CEO Richard Peters [BostonInno, May 31, 19]

Pushing back, proudly. As the economic relationship between the two countries frays at warp speed, the much-anticipated tech cold war is escalating. “If China continues to push back, and we continue to push back, there will soon be dual technology standards,” said Rebecca Fannin, author of the coming book “Tech Titans of China.” “Prices will probably rise for components, which companies will pass along to consumers. But both sides will strengthen their innovation edge, and that helps the global economy.” [David Streitfeld and Don Clark, New York Times, May 31, 19] Testosterone contest.

I could help anybody if I endorse them. I mean, we’ve had endorsements where they have gone up for 40, 50 points at a shot. [Our Pres abroad with mouth in gear.

History, the enemy. History has become an ideological tool, with certain episodes celebrated for showing the party’s best version of itself, while others are rooted out and erased. [Louisa Lim, New York Times, Jun 2, 19] Who controls the past controls the future. [George Orwell, 1984 in 1948]

Tocagen up 21% [May 30, 19]

BioCryst Pharma up 15% [May 30, 19]

Akero Therapeutics (South San Francisco, CA; no SBIR, founded 2017) set a preliminary $86.2 million [IPO] target among the growing number of biotechs developing drugs to treat nonalcoholic steatohepatitis (NASH), a type of fatty liver disease that has no FDA-approved therapies. Akero acquired its NASH drug, AKR-001, from Amgen, which the IPO filing shows owns a 5 percent stake in the company. [Frank Vinluan, xconomy.com, May 29, 19] total funding $135M [crunchbase.com]

Adaptive Biotech (Seattle, WA; at least $2.5M SBIR, founded 2009, 300+ employees) a high-flying startup that makes technology to read the human immune system, has officially filed to go public to raise $230 million [James Thorne, geekwire.com, May 30, 19] total funding $400M [crunchbase.com]

Prevail Therapeutics (New York, NY; no SBIR) is eyeing a $100 million IPO to continue development of gene therapies to treat neurodegenerative disorders. The company’s lead program, PR001, is an experimental treatment for Parkinson’s disease in patients who have a particular genetic mutation. says in its prospectus that the drug is also being developed to treat the neurological effects of Gaucher disease, an enzyme deficiency disorder. [Frank Vinluan, xconomy.com, May 28, 19]

CardioFocus (Marlborough, MA; $300K SBIR, founded 1990), dedicated to advancing ablation treatment for atrial fibrillation (AFib), announced the completion of a $55 million round of financing. [company press release, May 29, 19] prior funding $220M [crunchbase.com]

Preclinical biotech Atreca (Redwood City, CA; no SBIR, founded 2010) set a preliminary $100 million [IPO] target, which it says will finance development of its cancer immunotherapies. uses the immune system to guide researchers to discover pairs of antibodies and their targets. Atreca says that its technology has discovered more than 1,400 antibodies that bind to tumor tissue from patients who are not the source of the antibodies. [Frank Vinluan, xconomy.com, May 28, 19] total funding $223M [crunchbase.com]

EndoGastric Solutions (San Mateo, CA; no SBIR, founded 2003) announced the closing of its Series I financing at a total of $45 million. [company press release, May 28, 19]

Thrive Earlier Detection (Baltimore, MD; no SBIR, founded 2019) has raised $110 million to commercialize a cancer-detecting blood test, developed by Johns Hopkins researchers, that doctors would give patients during routine physicals. [Lorraine Mirabella, Baltimore Sun, May 30, 19]

Viela Bio (Gaithersburg, MD; no SBIR, MedImmune spinoff) landed a $220M agreement for Chinese pharmaceutical company Hansoh Pharmaceutical Group to commercialize Viela's lead drug candidate. The partnership allows Hansoh to develop and sell Inebilizumab, the local biotech firm's product for autoimmune diseases. [DCInno, May 29, 19]

AstraZeneca (UK) is starting to look at cutting some of the fat from its external pacts, and Inovio Pharmaceuticals is in the crosshairs. AstraZeneca's biologics arm MedImmune and Inovio have a long history, penning a deal back in 2015 worth $27.5 million upfront and up to $700 million in milestones for work on Inovio's cancer vaccines. [Ben Adams, Fierce Biotech, May 29, 19]

Going Big. [NIH] awarded up to $35 million to an international consortium led by a top San Diego virologist [Erica Ollmann Saphire of the La Jolla Institute of Immunology]to find treatments for viral threats, including Ebola and Lassa fever. [Bradley Fikes, San Diego Union Tribune, May 29, 19]

The career G-man [Special Counseel Robert Mueller] is bound by the rules. He made it clear that the president is bound only by Congress. [Russell Berman, govexeec.com, May 30, 19] At least a few people still respect rules in a political arena mostly ruled by partisan myopia. Lose your rules, lose your counter-balancing mechanisms.

Tariffs for all seasons. Trump said the U.S. would impose a 5% [and growing monthly] tariff on Mexican imports in frustration over the continued flow of asylum-seeking Central American families to the southern border. [Wall Street Journal, May 31, 19] With enough tariffs he thinks he can build his castle walls for America Alone.

Kezar Life Sciences (S San Francisco, CA; no SBIR, founded 2015) down 41% [May 28, 19] a clinical-stage biotechnology company discovering and developing novel small molecule therapeutics to treat unmet needs in autoimmunity and cancer, announced that data from the first two cohorts of an open-label dose escalation trial of KZR-616 in patients with systemic lupus erythematosus (SLE) will be featured in a poster presentation at the European League Against Rheumatism (EULAR) 2019 annual meeting [company press release, May 28, 19] total funding $78M plus IPO 2018 [crunchbase.com]

Slipping our grip. Singapore leapfrogged the U.S. to become the world’s most competitive economy, according to the latest rankings by Swiss-based IMD World Competitiveness Center. ... U.S.’s drop from first the third. [Jeff Sparshott, Wall Strreet Journal, May 29, 19] Our wealthy can keep their tax cuts and the rest of us get higher after-tariff prices and lower incomes. Elections have consequences.

Expecting ethical government? The [Washington] Post writes about how Trump has repeatedly pressured the Army Corps of Engineers and the Department of Homeland Security to award a contract for building a wall at the southern U.S. border to a North Dakota company headed by a leading Republican donor. ... [company CEO] has wisely made himself a fixture on Fox News, which the president watches obsessively. [David Graham, DefenseOne, May 28, 19]

Rockville-based biotech Vigene Biosciences announced the close of a $7.5M Series A round to fund the completion of a new facility. The move will more than double its current footprint, giving it dedicated space to develop, manufacture and test drugs. [DCInno, May 28, 19]

year-old MedImmune spinoff Viela Bio, created to focus on autoimmune disease, is raising $75M and could hit the 100-employee target by yearend. The funding would add to a $282M Series A round led by three Chinese investment groups when it launched in February 2018. [May 28, 19]

Kytopen, a startup working on gene-modified cell therapies, announced it has raised $3.6M in seed financing [Boston Business Journal,May 28, 19]

Up the blocked staircase. The CIA-affiliated venture-capital firm In-Q-Tel has nurtured many promising technology start-ups with seed money. But getting any technological innovations to take root inside the intelligence agencies has been a challenge, thanks to embedded contractors with their own financial incentives, bespoke and aging information technology systems, and sclerotic, risk-averse acquisition policies that make it exceptionally difficult for commercial companies, especially start-ups, to work with the government. [Amy Ziggart and Michael Morell, Foreign Affairs, M/J19] The inventors of SBIR claimed that getting more private firms into federal R&D would improve the adoption of new technology. The wiser heads in Congress knew better but were carried along on the chance to reward a politically favored group.

RNA-altering startup Stoke Therapeutics (Bedford, MA; no SBIR) filed for an $86M IPO.... developing treatments for diseases in which a genetic mutation leads to a protein deficiency. says it is focusing on autosomal dominant diseases, which are disorders in which only one copy of the gene needs to be mutated for the disease to develop. [Frank Vinluan, xconomy.com, May 24, 19]

Inhibrx (La Jolla, CA; SBIR, founded 2010), developer of protein drugs targeting cancer and other diseases, has raised $40 million as the biotech steers several programs through early-stage clinical trials. [Sarah de Crescenzo, xconomy.com, May 24, 19]

Dynavax Tech (Berkeley, CA; $6.3M SBIR, founded 1996) is pulling out of immuno-oncology R&D, laying off 82 staff and parting company with its CEO. The actions will create a slimmed-down commercial-stage company focused on selling hepatitis B vaccine HEPLISAV-B. [Nick Paul Taylor, Fierce Biotech, May 24, 19] total funding $175M [crunchbase.com]

Locana (San Diego, CA; no SBIR), a biotech working on gene therapies that target RNA rather than DNA, raised $55 million to expand its platform and pipeline as well as to build out its leadership team. The company is taking aim at diseases such as Huntington’s and amyotrophic lateral sclerosis (ALS) that are caused by problems in RNA that stop cells from producing essential proteins. [Amirah Al Idrus, Fierce Biotech, May 23, 19]

Tocagen down 39% [May 22, 19] announced the Toca 5 Phase 3 clinical trial evaluating Toca 511 & Toca FC in patients with recurrent high grade glioma (HGG) continues without modification following a planned interim analysis of data conducted by an Independent Data Monitoring Committee (IDMC). [company press release, May 21, 19]

RE2 Robotics received $3 million from the Office of Naval Research to develop an underwater, dextrous robotic hand for use in the U.S. Navy. [Julia Mericle, Pittsurgh Business Journal, May 20, 19[

Big ideas too big. A $10 billion data cloud, giant ray guns in space, a sixth-generation fighter jet — these are just some of the biggest ideas out of the Pentagon in the last several years. But they’ve failed to impress the House Appropriations Committee. [Patrick Tucker, Defense One, May 22, 2019]

Threating paralysis. President Trump abruptly blew up a meeting with Democratic congressional leaders, declaring that he could not work with them until they stopped investigating him. [NY Times, May 22, 19] A reactionary dream: the goverrnment promises nothing to discomfort the comfortable, plus an executive threat to attempt rule by decree. Eventually even the Republicans will object. SBIR's problem: the agencies will likely protect their mainline programs by deferring SBIR awards until the last week of the fiscal year.

Viasat landed a potential $450M indefinite-delivery/indefinite-quantity from the General Services Administration to provide technology platforms and services for both special operations and general purpose forces. [Matthew Nelson, GovConWire, May 21, 19]

NanoVibronix (New York, NY; no SBIR) up 49% [May 21, 19] noninvasive biological response-activating devices. It targets wound healing and pain therapy [Wall Street Journal]

Array Biopharma up 23% [May 21, 19]

BioCryst Pharma down 53% [May 21, 19] announced that the randomized (n=121), double-blind, placebo-controlled, Phase 3 APeX-2 trial of once-daily, oral BCX7353 for the prevention of hereditary angioedema (HAE) attacks achieved its primary endpoint [company press release, May 21, 19]

Reneo Pharmaceuticals (San Diego, CA and UK; no SBIR) a clinical stage pharmaceutical company, announced that it has completed a $50 million Series A financing to develop therapies for diseases associated with deficits in cellular metabolism and energy production. [company press release, May 20, 19]

Actuate Therapeutics (Ft Worth, TX; no SBIR, founded 2015) raised $21.7 million to take its lead oncology asset deeper into the clinic. The series B round comes shortly after Actuate dosed the first patient in a phase 1/2 trial of glycogen synthase kinase‐3 beta (GSK-3β) 9-ING-41. [Nick Paul Taylor, Fierce Biotech, May 20, 19]

ArcherDX (Boulder, CO, no SBIR), a molecular technology company dedicated to developing breakthrough solutions that advance the application of personalized genomic medicine, announced the closing of an up to $60 million Series B financing round [company press release, May 15, 19]

Marrone Bio Innovations (Davis, CA) maker of biologically based pest control products, said it's partnering with Compass Minerals International (Overland Park, KS) to develop new sustainable plant nutrition products. [Mark Anderson, Sacramento Business Journal, May 16, 19]

Iovance BioThera (San Carlos, CA; no SBIR) up 36% [May 16, 19] reaction to new interim data from clinical trials evaluating its tumor-infiltrating lymphocyte (TIL) candidates. The data will be presented at ASCO in Chicago. [Douglas W. House, seekingalpha.com, May 16, 19]

Mersana Thera down 16% [May 16, 19]

Dynetics was one of eleven companies picked by NASA to produce prototypes of a human [lunar] landing platform with descent, ascent, transfer and refueling elements and shoulder at least 20 percent of the total development cost under the Next Space Technologies for Exploration Partnerships Appendix E contracts. [Jane Edwards, GovConWire, May 17, 19]

Already struggling to keep pace with Sarepta Therapeutics in the race to develop a gene therapy for Duchenne muscular dystrophy, Solid Biosciences reported another setback. A patient treated with its Duchenne muscular dystrophy gene therapy suffered a transient decline in platelet levels from the gene therapy, and a serious GI infection that wasn’t related to the treatment. The patient recovered and the trial continues, but shares nonetheless fell 40 percent. [Frank Vinluan, xconomy.com, May 17, 19]

ElevateBio unveiled $150 million in Series A funding to back its plans to invest in cell and gene therapy startups, and build a shared facility in Waltham, MA, that will manufacture their experimental treatments. [Frank Vinluan, xconomy.com, May 17, 19]

clinical-stage biopharmaceutical CinCor Pharma (Cincinnati, OH; no SBIR, founded 2018) announced the completion of a $50 million Series A round. ... the largest Series A the city has ever seen. ... also CinCor announced that Swiss multinational health care company Roche would acquire exclusive global rights to CIN-107, an aldosterone synthase inhibitor compound. Said compound will be further developed to use against treatment-resistant hypertension and primary aldosteronism. Financial terms of the deal were not disclosed. [Courtney Gabrielson, CincyInno, May 15,19 ]

Usual SBIR politics. The Senate Small Business Committee held a hearing on “Reauthorization of the SBA’s Innovation Programs,” which had a heavy emphasis on SBIR/STTR. Earlier in the day, Chairman Marco Rubio (R-Fla.) published a report on business investment, which places many shortcomings of the national economy at the feet of “sharedholder primacy” and calls for policies to incentivize investment by businesses into research and innovation. Among the topics raised during the hearing were making SBIR/STTR permanent, faster contracting, and additional support for innovative companies. [Jason Rittenberg, SSTI, May 16, 19] Usual noises that beneficiaries love SBIR for three decades, but no defensible economic evaluation. No matter, small money for beloved constituency, little harm done to government R&D.

In the Archives older stories back to 1996

news and views about government programs, politics, attitudes ...1996-1997; 1998; 1999; Y2K; 2001 , 2002-2003 ; 2004-5; 2006; 2007-08 2009-2010; 2011-2012; 2013-14 ; 2015; 2016; 2017-18

BMDO/ MDA including SBIR the doings of star wars

Miscellaneous Stories 1996-1997; 1998-1999; 2000-2001; 2002-2003 ; 2004-5 ; 2006; 2007 2009-2010 ; 2011-2012; 2013-2014; 2015; 2016; 2017

IPO and Venture Markets 1996-1998 .... 1999-2005 ... 2006-present

Quotes steal them if you like

Note: in these old stories, many links are dead, obsolete, or missing

Stories about companies; 1-Al .. Am-Az .. B .. C ... D-E .. F .. G-H .. I-J .. K-L .. M ... N-O ... P ... Q-R .. S1-Se .. ... Sf-Sz .. T-U .... V-Z

Companies in the Archives

10X Genomics ..... 1366 Technologies ... 1st Detect ... 21-Century Silicon ... 21st Century Systems .... 23andMe ... 24M Technologies ... 30 Second Software ... 360fly ..... 3Bar Biologics .... 3C Semiconductor ... 3DEO .... 3D Glass Solutions ..... 3Dnamics ..... 3D Robotics .... 3D Systems ..... 3D Technology Laboratories .... 3F ... 3iNanotech .... 3PrimiR ... 3Scan ..... 3-V Biosciences .... 3VR ... 410 Medical Innovation .... 454 Life Sciences .... 4C Medical Technologies .... 4D Molecular Therapeutics ..... 4s3 Bioscience ... 5D Robotics ..... 7AC Technologies ... 89Bio ... 908Devices ... 9Mile Labs

A10 Networks ... A123Systems ... A4 Pharma .... A&G Pharmaceutical ... Aastrom Bioscience .. Abacus Technology ... ... Abaxis .... Abcombi Sciences ..... Abeona Therapeutics ..... AbGenomicsInternational ... Abiomed ... Ablative Solutions .... Ablexis ...... ABL Technologies .... Abpro Therapeutics ..... AbSci .... Absorbent Materials ... Abundant Robotics ..... AbVitro ... Acadia Pharma ... Acambis .. Accel Diagnostics ..... Acceleron Pharma ... Accelrys ... Accentia BioPharmaceuticals ... Accent Therapeutics ..... Accera .... Access Pharmaceuticals ... Access Scientific .... Accion Systems ..... Accumetrics ... AccuraGen ..... Accurate Automation .. Accuray ... Accuri Cytometers ... Acelerox .... Acelity .... AcelRx Pharmaceuticals ... Acera Surgical .... Acetylon Pharmaceuticals ... Achaogen ... Achates Power ..... Achillion Pharmaceuticals ... ACIST Medical Systems .... Acorda Therapeutics ... Acorn Cardiovascular ... Acquia .... AcroMetrix ... AcryMed ... ActaCell ... Actasys .... ACT Biotech ... Active Power ... ActivBiotics ... ActivMedia Robotics .... Acton Pharmaceuticals ... Actuality... Acucela ... AcuFocus .... Aculight ... Acumentrics ... AcuraStem .... Acutus Medical .... Adamas Pharmaceuticals ...... Adamis Pharmaceuticals ... Adapteva .... Adaptimmune Therapeutics .... Adaptive Biotechnologies ..... Adaptive Computing ... Adaptive Phage Therapeutics ..... Adaptive TCR ... Adarza BioSystems ..... Addiction Therapeutix ... Addrenex Pharmaceuticals ... Adelor ... Adenosine Therapeutics ... Adesto Technologies .... Adeza Technologies ... Adherex Technologies ... Adhesys Medical .... Adial Pharmaceuticals .... Adicet Bio .... AdiMab ... ADispell ... Adlyfe .... ADMA Biologics .... Admittance Technologies .... Admune Therapeutics ..... Adnexus Therapeutics ... Adrenergics .... Advanced BioHealing ... ADS Biotechnology ... Aduro BioTech .... Advanced Animal Diagnostics .... Advanced Biologics ..... Advanced Bionics ... Advanced Cell Diagnostics ... Advanced Cell Technology (now sub to Bio-Techne) ... Advanced Ceramics .... Advanced Circulatory ..... Advanced Countermeasures Systems ... Advanced Diamond Technologies .... Advanced Electron Beams ... Advanced Fuel Research ...Advanced Life Sciences ... Advanced Lighting Technologies ... Advanced Liquid Logic ... Advanced Magnetics ... Advanced Photonix .... Advanced Programming Concepts ... Advanced Receiver Technologies .... Advanced Scientific Concepts ..... Advanced Targeting Systems .... Advanced Technology Materials.(ATMI) ... Advanced Uro-Solutions ..... AdvanDx ... Advantic ..... Advaxis ..... Adventrx ... Adverum Biotechnologies ..... Advion BioSciences ... Adynxx ...... Aegea Medical ... Aegerion Pharmaceuticals .... Aeglea BioTherapeutics Holdings ..... Aerial BioPharma .... Aerie Pharmaceuticals ... Aerin Medical ..... AerisPhotonics ...... Aerius Photonics ... Aerodyne Research ... Aero Farms System ... Aerovel ..... AeroVironment ... Aerpio Therapeutics .... AesRX ... AETC ... Aethlon Medical ... Aethon .... Aevi Genomic Medicine ..... Affectiva .... Afferent Pharmaceuticals ..... Affigen .... Affinimark Technologies ... Affinity BioReagents ... Affinium Pharmaceuticals ..... Affinivax .... Affomix .... Affymax ....Affymetrix ... aFraxis ... AgBiome ..... AgeneBio .... Agennix ... Agenovir ..... Agenus .... Agere Pharmaceuticals ..... Agile Materials ... Agile Planet ... AgileSwitch .... Agile Therapeutics .... Agility Robotics ..... Agilis Biotherapeutics .... Agiltron...Agilvax .... Agilyx .... Aagios Pharmaceuticals... AgraQuest .... Agritope... Agrivida ... Agro Biosciences .... Aguila Technologies.....Ahura Scientific.... Aiko Biotechnology ... Aileron Therapeutics .... Aimmune Therapeutics (formerly Allergen Research) ..... airtricity... Airware .... Airxpanders .... Airway Therapeutics .... ait laboratories... Akadeum Life Sciences .... Akamai Physics Akarna Therapeutics ..... Akashi Therapeutics ..... Akcea Therapeutics ..... Akebia .... Akero Therapeutics ... Akermin ..... Akers BioScience ..... Akita Innovations ... Akouos .... Akrevia Thera .... Akron Polymer Systems ..... Akron Surface Technologies ..... Akros Medical .... Alabama Cryogenics ... Alafair Biosciences .... Albany Molecular (AMRI) ...A? nanotech .... Alcon .... Alcresta .... Aldagen ... Aldatu Biosciences ..... Aldea Pharmaceuticals ... . Alder biopharma Aldevon ..... Aldeyra Therapeutics (formerly Aldexa Therapeutics) .... Alector .... Alexar Therapeutics ..... Alexion ... ....Alexza .... Alfalight.... Algaeventure Systems ... Algenetix .... Algeternal .... Algorithmia ..... Alien Technology .... Alimera sciences.... Alios BioPharma ....Aliva biopharmaceuticals ..... AliveGen .... Alivio Therapeutics ..... Alkermes... Alkeus Pharmaceuticals ... Allakos ... Allcast .... Allegro Diagnostics .... Allegro microsystems ... Allena Pharmaceuticals .... Allergy Amulet ..... Allerquest .... Alleviant Medical .... Allied BioScience ..... Allied Minds .... Alliqua .... Allos Alloy Polymers .... Alloy Surfaces ..... Allurion Technologies ... Allylix ... Alnara Pharmaceutical ... Alnylam... Alper Biotech ... Alphabet Energy .... AlphaCore Pharma ... Alphamed.... Alphatec Holdings ..... Alphavax ... Alpine Biosciences .... Alpine Data Labs .... Alpine Immune Sciences ..... Alseres .... Algeternal .... Alta Devices ... AltAir Fuels ... Altair Therapeutics ... Altamira Technologies .... AltaRock ... AltheaDX .... Althea Technologies ... Altimmune ..... Altor ... Altra ... Altura Medical ... Altus Pharmaceuticals ... ALung Technologies ... Alvine Pharmaceuticals .... Alzeca ..... AMAG Pharmaceuticals ... Alzheon ..... Amaranth Medical .... Ambarella ..... Amberwave ... Ambiq Micro .... Ambit Biosciences .... AMBP Technology ... Ambri .... Ambrx ... Ambry .... Ambys Medicines .... Amendia .... American Bionics ..... American Gene Technologies International .... American Lithium Energy .... American Medical Systems .... American Science and Engineering ... America Stem Cell, now Targagyme .... American Superconductor ... American XTAL .. Ames Technology ... Amgen ... Amicus Therapeutics .... Amionx ..... Amnis ... AMO Pharma ..... Ampio Pharmaceuticals ..... Ampla Pharmaceuticals ... Amplimmune .... Amplyx Pharmaceuticals ..... Amprius .... ARMO BioSciences .... Amylin Pharmaceuticals ... Amylyx ..... Amyris Biotechnologies ... Anacor Pharmaceuticals ... Anadys Pharmaceuticals ... Anakim Biologics .... Analog Computing Solutions .... Analytical Space ..... AnaptysBio ... Anavex Life Sciences .... Anchor Therapeutics ... Ancora Pharmaceuticals ... AnDAPT ..... Anexon .... Anew Optics ... Angeion ... AngioDynamics ... Angiologix ... Angstrom Medica .... Angstron Materials ... Animalgesic Labs .... ANI Pharmaceuticals ... Animetrics .... Anivax .... Anivive Therapeutics ..... Annexon Bioscience ..... ANP Technologies ..... Ansoft ... Ansun Biopharma (formerly NexBio) .... Antegrin Therapeutics ..... Anthera Pharmaceuticals .... Anthos Therapeutics ..... Antigenics ... Anue Systems ... Anulex Technologies ... Anybots ... AOBiome Therapeutics (formerly Nitrocell) .... AOptix Technologies ... Aortica ..... APA Optics (Enterprises) ... Apellis Pharmaceuticals ..... Apexigen ... Aperion Biologics .... Aphios ... Apic Bio .... Apieron ... Apnex Medical ... ApniCure ..... ApoCell .... ApoGen Biotechnologies .... Apollo Diamond ... Apollo Endosurgery ... Apollomics (previously CBT Pharmaceuticals) .... Apoplogic Pharmaceuticals ... Applied Biomolecular Technologies .... Applied Biosystems .... Applied Defense Solutions ..... Applied Genetic Technology ... Applied Nanotech .... Applied NanoWorks ... Applied Optimization ..... Applied Optoelectronics ... Applied Physical Electronics ... Applied Physical Sciences ... Applied Precision ..... Applied Proteomics ..... Applied Quantum Technologies .... Applied Quantum Technology .... Applied Research Associates ... Applied Science and Technology ... Applied Signal Technology ... Applied Therapeutics ...... AppThwack .... Aprecia Pharmaceuticals .... Apricus Biosciences ... APS BioGroup .... Apse .... Aptalis Pharma .... Aptevo Therapeutics ..... Aptima ... AptamiR Therapeutics .... Aptinyx .... Aptose Biosciences .... Aptus Endosystems ... Aquaback Technologies ... Aqua Bounty ... Aquacue .... AquaHarmonics ..... Aqua Metals .... AquaMost ... Aquarius Technologies ... Aquestive Therapeutics .... AqueSys ... Aqueti .... Aquion .... Aradigm .... AragonPharmaceuticals ... Aratana Therapeutics ..... Arbor Biosciences< ..... Arbor Biotechnologie ..... Arbor Pharmaceuticals ... Arbovax ... Arbutus BioPharma (formerly OnCore) ..... Arca Biopharma .... Arcadia Biosciences ..... Arcadia Pharma ..... Arcantatura... Archemix ... ArcherDX ......Arch Innotek ..... Arch Oncology ..... Arch Therapeutics ... Arctic Sand Technologies .... Arcturus Therapeutics .... Arcus Biosciences ..... Ardea Biosciences ... Ardelyx .... Ardian .... Arena Pharmaceuticals ... Argentum ..... Arginetix ... Argo AI ..... ArgonST ... Argos Therapeutics ... Aria CV ... Ariad Pharmaceuticals .. Ariosa Diagnostics ..... Arista MD .... Arista Networks .... ARIZ Precision Medicine .... Arkis BioSciences ....... Arkansas Power Electronics ..... Armadillo Aerospace ... Armetheon .... ARMO BioSciences .... Armonica Technologies .... Armorworks ... Armune BioScience ..... Aro Biotherapeutics .... Aronora ..... Arpeggi .... ArQule ... Arrakis Therapeutics ..... Array ... Array Information Technology ..... Arresto Biosciences .... Arrien Pharmaceuticals ... Arrivo BioVentures ..... Arrowhead Pharmaceuticals ..... Arrowhead Research .... Arsanis ... Arsenal Medical .... Arstasis ... Artel .... Arteriocyte ... Arterys ..... ArthroCare ... Arthrosurface ... Artisan Pharma ... Artrility Medical ..... Arvegenix ..... Arvinas .... Arxan Technologies .... Aryx Therapeutics ..... Aryx ... Arzeda ... Asana Medical (now Regentsys) .... Asante Solutions ..... Ascelegen Therapeutics .... Ascension Orthopedics ... Ascent Solar Technologies .... Ascent Therapeutics .... AsclepiX Therapeutics .... Aseptia .... Ash Access Technology .... AstroWatt .... Aspen Aerogels .... AspenBio Pharma .... Aspen Products Group .... Aspen Technology ... Aspyrian Therapeutics .... Assurex Health ..... Astex Therapeutics ... Asthmapolis .... Astralux ... Astrobotic Technology .... Astronautics Corp. of America ... AstroPower... AstroTerra .. Astrum Solar ... Astute Medical .... Astute Medicales ... Asuragen ... Atacama ..... Atara Biotherapeutics ..... Ataxion .... Athenex (formerly Kinex) ..... Athenix ... Athens Research ..... AtheroGenics ... AtheroMed .... Athersys .... ATI Industrial Automation ... Atlantia ... Atmocean ..... Atmospheric Glow Technologies ... Atomate ... Atomic Medical Innovations ..... Atomometrics ... Atomwise ..... Atoptix .... Atossa Genetics ... Atreaon .... Atreon Orthopedics ..... AtriCure ... Atrium Medical ... ATRP Solutions ... aTyr Pharma ..... Audentes Therapeutics ..... Audience ... Augmenix .... AUM Cardiovascular ... Aura Biosciences .... Auris Health .... Auris Medical .... Auris Surgical Robotics ..... Aurora Algae ... Aurora Flight Sciences .... Aurora Imaging Technology ... Aurora Spectral Technologies ... Auspex Pharmaceuticals ... Ausra ... Auterra .... AuthenTec .... Autolus Therapeutics .... Automated Dynamics ... Automated Medical Instruments .... Autonet ... Aushon Biosystems ... AutoGenomics .... Autonomic Materials .... Autonomic Technologies ..... Autonomous Technologies .... Auxilium Pharmaceuticals ... Avalanche Biotechnologies .... Avanir Pharmaceuticals ... Avant Immunotherapeutics ... Avanti Metal ... Avaxia Biologics ... Avedro ... Avelas Biosciences .... Aveo Pharmaceuticals ... Avery Therapeutics ..... AveXis .... Aviation Resources Delaware .... AVI BioPharma ... Avici Systems ... AvidBiotics .....Avidity Biosciences .... Avid Radiopharmaceuticals ... Avila Therapeutics ... Avinger .... ... Aviragen Therapeutics (formerly Biota Pharmaceuticals) ..... Aviron ..... Avita Medical Americas ..... Avitude .... Avrobio ..... AVT Simulation .... Aware ... Axcella Health (was Pronutria) ..... Axelo .... Axerion Therapeutics ... Axial Biotech .... Axial Biotherapeutics ..... Axion BioSystems ..... Axion Power ... Axis Clinicals .... Axis Semiconductor ... Axium Nanofibers ...... Axium Pharmaceuticals .... Axogen .... Axonia Medical ....Axonics Modulation Technologies Axsome Therapeutics ..... Axsun Technologies ... Ayasdi ..... Azaya Therapeutics ... Azelon Pharmaceutical ... Azimuth .... Aziyo Biologics ..... Azure Biotech ..... AzurRx BioPharma

Baby Genes .... Bacterial Robotics .... BacterioScan .... Baebies ..... Bagaveev .... Ballard Power ... Bamboo Therapeutics ..... Bandgap ... Banner Life Sciences ..... Banyan Biomarkers ... Bardy Diagnostics .... BarioSurg ..... Baryonyx .... Barrier Therapeutics ... Baseload Renewables .... Basis Science .... Bastion Technologies .... Batu Biologics ..... Bauhaus Software ..... Baxano ... Baxano Surgical .... BayoTech ..... Beacon Biomedical ..... Beacon Power ... Beam Therapeutics ..... Beat Biotherapeutics .... Beeco ... Behavioral Recognition Systems .... Bellicum Pharmaceuticals .... Belmont Instrument .... Benchmark Automation ... BeneChill ... Benefuel ... BeneVir Biopharm .... Bennett Aerospace .... Benson Hill Biosystems ..... Benvenue Medical .... Berg .... BerrieHill Research ... BESS Technologies .... BetaBatt ... BetaLED .... LEDBG Medicine ... Bettergy .... Bexion Pharmaceuticals .... Bina Technologies .... Bind Bioscience ... Bind Therapeutics .... BinOptics ..... BiO2 Medical ... BiO2 Technologies ... BioAmber ... BioAdvanTek ... BioAffinity Technologies ..... Bioanalytical Systems ... BioBehavioral Diagnostics ... BioBridge Global ..... BioCardia ..... BioCentra Molecular Innovations ..... Biocept ... BioChemics ..... BioClin Therapeutics .... Bicycle Therapeutics ..... Bien-Etre Labs ..... BioCold Genesys .... Bioconnect Systems .... BioConsortia ..... BioCritica ... BioCryst Pharmaceuticals ... BioDelivery Sciences ... Biodesix .... BioDirection ..... BioDtech ... BioFactura ... ..... BioE ... BioFire .... BioFluidica ..... Biogenic Reagents .... BioGreenChoice ... BioHaven Pharmaceuticals ..... Bioheart ... Biohelix ... Bio-Imaging Technologies ... Bioincept .... BioKier ..... Biolex Therapeutics ... BioLife4D ..... BioLink Life Sciences ... Biolinq (formerly Electrozyme) ,,,, Biologics ... BioMagnetic Solutions .... BioMarin Pharmaceutical ... BioMarck Pharmaceuticals .... bioMASON ..... Biomatrica ... BioMedical Enterprises ... Biomedical Sciences ..... Biomedical Structures ... BioMedix .... Biomeme .... Biometric Signature ... BioMimetic Therapeutics ... BioMotiv .... BioNano Genomics ... BioNanomatrix ... Bionostics Holdings ... Bio-Path Holdings ..... Biophan Technologies ... Biophysical ... BioProcessors ... Bioptigen ... Bioptix .... BiOptix Diagnostics ..... BioPulping International ... Biopure ... Biorasis ..... BioRelix ... BioResource International ... BioRestorative Therapies (formerly Stem Cell Assurance) .... BioSante Pharmaceuticals ... BioScale .... BioSense Technologies ... BioSensics .... BioSentinel Pharmaceuticals ... BioSig Technologies ..... Biosortia Pharmaceuticals .... BioSphere Medical .... Biostage (formerly Harvard Apparatus Regenerative Technology) ..... BioStructures .... Biosurfaces .... Biosym Technologies later Accelrys .... BioSystem ... Biota Pharmaceuticals .... Bio-Techne ..... BioTechnique .... BioTechPlex ..... Biotectix .... Biotel .... BioTelemetry (formerly CardioNet) ..... BioTex .... Biothera ... BioTheranostics ... Bio Time ... Biotix ... Biotronic NeuroNetwork ..... Biotronik .... BioTrove ... BioVaxys .... Bioventus ..... Biovest International .... BioVex ... BioVirtua ..... Bird Rock Bio (formerly RuiYi) ..... Birich Technologies .... Biscayne Neurotherapeutics ..... Bitstream ... Black Diamond Therapeutics .... Black-I Robotics ... Black Sand ... BlackThorn ..... BladeLogic ... Blasch Precision Ceramics .... Blaze Bioscience ... Blend Therapeutics .... BL Healthcare ... Block Engineering ... Bloom Energy ... Bloo Solar ..... BluDiagnostics ..... Blue Belt Technologies ... Bluebird bio ... BluDiagnostics .... Bluefin Robotics ... Bluegrass Proteins .... Bluegrass Vascular Technologies .... Blueprint Medicines ... BlueRock Therapeutics ..... Blue Sky Batteries ... Bluewater Bio International ... Bolder Surgical ... Bolt Biotherapeutics .... Bolt Threads .... Boom Supersonic ..... Boragen .... Boston Biochem ... Boston Biomedical ... Boston Dynamics ... Boston Engineering ... Boston Micromachines ... Boston Micromachines (formally Boston Electrometallurgical .... Boston-Power ... Boston Therapeutics ... Bot Dolly .... Boundless ... BoXZY ..... Braeburn Pharmaceuticals ..... BrainCells ... BrainScope .... Brain Sentry .... Brain Tunnelgenix Technologies .... BrainXell ..... Branch Medical Group ..... Brayton Energy .... Breathe Technologies ... Breethe .... Breonics ... BreviTest Technologies ..... Brewer Science ... Bridger Photonics .... Bridgelux ... Brightsource Energy ... Bright View ... Brimrose Corp of America ... Briteseed .... Brock Rogers Surgical ... Bromium .... Brooks Automation ... Bruker Daltonics .... Buffalo BioLabs ..... Burl Concepts ..... Burr Oak

C12 Energy ... C2Sense .... C3Nano ... C4 Therapeutics .... C8 Sciences .... C9 ... Cabaletta Bio .... CABG Medical .... Cadence Pharma .... CadheRx Therapeutics ..... Caisson Biotech .... Calabazas Creek Research .... Caladrius Bioscience ... Cala Health ..... Calando Pharmaceuticals ... Calbiotech .... Calera ... Caliber Biotherapeutics .... Calibra Medical ... Calient ... California Wave Power Technologies ..... Calimmune ..... Caliper Life Sciences .... CaliSolar ... Calistoga Pharmaceuticals ... Calithera BioSciences .... Calixa Therapeutics ... Callidus Biopharma ... Calporta Therapeutics .... Calspan .... Caltech Metals ... Calysta .... Calyxt ..... Cambridge Endoscopic Devices ... Cambridge Heart .... Cambridge Research & Instrumentation ... Cambrios Technologies .... CAMX ..... Candela Laser .... Cancer Genetics .... Cancer Prevention Pharmaceuticals .... CanDiag .... Canopy Biosciences ..... Capesym ... Capillary Biomedical ..... Capio Biosciences .... Capnia ... CAPP Medical ..... Capricor Therapeutics .... Cara Therapeutics .... Carbon ..... Carbon Design Systems ... Carbtex Technology .... Carbylan Therapeutics ..... Cardeas Pharma .... CardiacAssist ..... Cardiac Concepts ... Cardiac Dimensions ... Cardiac Science ..... Cardialen ..... CardiAQ Valve Technologies ... Cardica ... CardioDx ... CardioFocus ... CardioInsight Technologies ..... Cardiokinetix ..... CardioMag ... CardioMEMS .... Cardionomic .... CardioNXT ..... Cardiorobotics ... Cardiosolutions ... Cardiosolv .... CardioSpectra ... CardioTech ... Cardiovate ..... CardiOx ... Cardioxyl Pharmaceuticals .... CareDx (formerly XDx) .... Caribou Biosciences ..... Carigent Therapeutics .... Carisma Thera (formerly CARMA Therapeutics) ..... Carmot Therapeutics ..... Carnegie Robotics .... Carnegie Speech ... .... Carnot BioSciences .... CaroGen .... Carter Aviation Technologies .... Carticept Medical ... Cartiva ..... Cascade Designs ... Cascade Microtech ... Cascadian Therapeutics (formerly Oncothyreon) ..... Casma Therapeutics .... Castle Pharmaceuticals .... Castle Creek Pharmaceuticals Catabasis Pharmaceuticals ... Catadon Systems ... Catalyst Biosciences ... Catalyst Pharma .... Catalytic Innovations ..... Catalyze ..... Catelectric .... Cebix .... Cedarburg Pharmaceuticals .... Cedilla Therapeutics ..... CeeTox ... Celadon ... Celator Pharmaceuticals ... CelcuityCeldara Medical ..... Celladon .... Cellara .... Cell Care Therapeutics ..... Cellceutix .... CellCyte Genetics ... Cell Design Labs ..... Celldex Therapeutics ... ..... Cellectar ... Cellerant Therapeutics ... Celleration .... Cell Genesys ... CellRight Technologies ..... Cellular Bioengineering ... ... Cellular Bioengineering ..... Cellular Biomedicine Group ..... Cellular Dynamics International .... Cell>Point .... CellSavers ..... Cellscape .... Cellscript ..... Cell Signaling Technology ...Cell Therapeutics (now CTI BioPharma) ... CellTraffix ... CeloNova Biosciences ..... Cel-Sci .... Celsion ... Celtaxsys ..... Celula..... Celularity ..... CellzDirect ... Cempra Pharmaceuticals. .... CeNeRx BioPharma ... Centocor .... Centrexion Therapeutics ..... Centrose ... Centice ... Centritec Seals ... Cephalon ... Cepheid ... Cephalon ... Ception Therapeutics ... Cequent Pharmaceuticals ... Cerebras Systems ..... Ceradyne ... Ceramitron ... Cerapedics .... Ceramatec ... Cerevast Therapeutics .... Cerealus Holdings ... Cerecor .... Ceregene ... Cerahelix .. Ceres Nanosciences ..... Cerexa .... Cerion Enterprises ... Cermet ... Cernostics ..... Cerulean Pharma ... Cerus ... Cervel Neurotech .... Cesca Therapeutics .... Ceterix Orthopaedics ... CFD Research .. CFX Battery .... CGI Pharmaceuticals ... ChaCha ... Chantilly BioPharma .... Chapman Innovations ... Charles River Analytics .... Charles River Lab ... Charter Medical ..... Chase Therapeutics .... CHASM .... Chatham Therapeutics ..... Checkerspot ..... Chemat ... Chembio Diagnostic Systems .... ChemImage ... Chemir Analytical Services ... ChemoCentryx ... Chemtura .... Chesapeake Sciences ...Chesson Labs ... Chiasma .... Chimera Bioengineering ..... Chimerix ... Chlorogen ... Choice Therapeutics ... Chondrogenics ... Chordia Therapeutics .... Chorum Technologies .... ChromaCode ..... ChromaDex ..... Chronix Biomedical ... Chrysalis BioTherapeutics .... Cibus Global ... Cidara Therapeutics .... Ciena ....Ciencia ... Cilion .... CimaBay Thera ..... CinRx .... Ciranova ... Circle Technologies ..... Cirius Therapeutics ..... CivaTech Oncology .... CiVi Biopharma ..... Civitas Therapeutics ..... Claret Medical .... Clarassance ..... Claresta Solutions .... Clark-MXR ...Claros Diagnostics .... Clean Diesel Technologies ... Clear Catheter Systems .... ClearCount Medical Solutions .... ClearEdge Power .... Clear Guide Medical .... Clearside Biomedical ... Cleave Biosciences ... Cleveland BioLabs ... Cleveland Polymer Technologies ..... CleverSet ... Clinical Data ... Cloudant ... CloudMade ... Cloud Pharmaceuticals (formerly Teradiscoveries) .... Clovis Oncology ... Clovis Tech ..... CMC Biologics .... C-Motive Technologies .... CoAdna,Holdings ..... CoAxia .... Cobalt Biofuels ... Cocrystal Discovery ... Codexis ... Codiak BioSciences ..... Codon Devices ... Co-D Therapeutics .... Cofactor Genomics .... Cogenra .... Cogentix Medical ..... Cognex ...Cognition Therapeutics .... Cognitive Code ... Cohera Medical .... Coherus Biosciences .... Cohesive Technologies ... ColdQuanta .... ColdWatt ... Collagenex Pharmaceuticals ... Collegium Pharmaceutical ... CoLucid Pharmaceuticals ... Columbia Labs ..... CombiMatrix ... CombinatoRx ..... Combined Energies .... Combinent BioMedical Systems ... Comfort Motion Technologies ... Commonwealth Biotechnologies ... Commonwealth Fusion Systems ..... Compact Membrane Systems ...Compass Therapeutics .... Compellent Technologies ... Compendia Bioscience ..... Complete Genomics .... Complexa ..... Conatus Pharmaceuticals ... Concert Pharmaceuticals .... Concordia Fibers ...Concurrent Technologies ... Conductus .. Confluence Life Sciences ..... ConforMIS ... Cognigen .... Conispire .... ConjuGon .. Connecticut Valley Bindery ... Consonus Technologies ... Constellation Pharmaceuticals .... Context Therapeutics ..... Contour Energy Systems ControlRadSystems ..... Convelo Therapeutics .... Conventus Orthopaedics ..... Convergen ... ConverGene .... Convio .... Convoy Therapeutics .... Cool-Bio .... CoolCAD Electronics .... CoolChip Technologies .... Cool Earth Solar .... Cooligy ... CoolTech .... Corbus Pharmaceuticals ..... Corcept Therapeutics ... Cordex Systems .... CoreStreet ... CoreTek ... .Corgenix Medical ... Corindus ....Corinthian Ophthalmic ... Corium International .... Corixa .... CorMatrix Cardiovascular .... Cornami ..... Cornerstone Research ... Cornerstone BioPharma then Cornerstone Therapeutics ..... Cornerstone Therapeutics .... Coronado Biosciences ... CorQuest Medical ..... Correx ... Corridor Pharmaceuticals ... Cortana ..... Cortendo AB ..... Cortexyme .... Corvidia Therapeutics ..... Corvus Pharmaceuticals ..... CosmosID ..... CoStim Pharmaceuticals .... Cougar Biotechnology ... Coulbourn Instruments .... Coulter Pharmaceuticals ... Cour Pharmaceutical Development .... Coverity ..... Creare ... Creative Hybrid Solutions .... Creatv MicroTech .... Cree Research ... Crescendo Bioscience .... Crinetics Pharmaceuticals .... CrispTek .... Critical Therapeutics .... CritiTech ... Crossbar .... Cross Current ..... CrossFire ... Cruise Automation .... Crux Biomedical ... CryoCor ... CryoLife ... Cryomedical Sciences ..... Cryptonite ..... Crystal IS ... Crystal Systems ... Crystallume ... CSA Engineering ... CS-Keys ... CTD Holdings ..... CTI BioPharma (formerly Cell Therapeutics) .... Cubist Pharmaceuticals ... Cue Biopharma .... Cullinan Oncology ..... Cumberland Pharma .... CuraGen ... Current Motor ... Curtana Pharmaceuticals .... Custom Electronics .... CVD Equipment ..... CVRx ... CV Therapeutics ... Cyanotech ..... Cyberdyne .... CyberKey Solutions ... Cyberkinetics Neurotechnology ... Cybernet Systems ... CyberOptics ... Cydan .... Cykloburn Technologies ..... CymaBay Therapeutics .... Cymbet ... CyMedica Orthopedics ..... Cymer ... Cynosure ... Cyntellect ... Cypher Genomics ... CyPhy Works ... Cypress Bioscience ... Cyrus Biotechnology ..... Cyteir Therapeutics ..... Cyterix Pharmaceuticals ... CytImmune .... CytoBioScience ..... Cytocentrics ..... CytoCore (formerly Molecular Diagnostics) ..... Cytocybernetics ..... CytoDyn .... Cytogel Pharma .... Cytokinetics ... Cytometix ....CytomX ... Cytonome .... Cytori Therapeutics ... Cytophil CytoSolv ... Cytosorbents ..... Cytovas ... CytRx ..... Cytyc ... CyVek

Dabble ..... Dairyvative Technologies ..... Daktari Diagnostics ... Dance Biopharm .... Dara BioSciences ... Daré Bioscience Operations .... Dart Therapeutics ... DaStrong .... Datafiniti .... Data Physics ... DataRobot ..... Dato (formerly GraphLab) .... Datuit .... daydream.io ..... Daylight Solutions .... DayStar ... DayZero Diagnostics ..... DBS Energy ... DCL Medical Laboratories ... Deca-Medics ... Decibel Therapeutics ..... DecImmune Therapeutics ... Deciphera Pharmaceuticals ..... Decision Biomarkers ... Deepwater Wind .. Defense Engineering .... Defense Research Associates .... Defibtech ... Dekkun .... Delcath ... Delinia ..... Deltanoid Pharmaceuticals ... Denali Medical ... Denali Therapeutics ..... Dendreon ... DeNovo Sciences .... DeNovis ... Deposition Sciences .... DermAvance Pharmaceuticals ... Dermira ... Desalitech .... Descartes Labs ..... Design Knowledge ..... DesignMedix ..... Detcon ..... DE Technologies ... Devicix ..... Dew & Ken Group ... Dewey Electronics ... Dewpoint Therapeutics .... Dexcom ... Dharmacon ..... Diagnostic Biochips .... Diagnostic Hybrids ... DiaMedica ..... Diamond Foundry ..... Dianomi Therapeutics .... Diatomix ..... Dicerna Pharmaceuticals ... Diffusion Pharma ..... DiFusion Technologies ... Digene ..... Digirad ... DigiSight Technologies ..... Digital Fusion ... Digital Lumens ... Digital Optics ... Dignify Therapeutics .... Dimien .... Dimension Therapeutics .... DioGenix .... Dipexium Pharmaceuticals ..... Directed Manufacturing .... Directed Perception .. Disarm Therapeutics .... Disc Dynamics ... Discovery Genomics ..... Discovery Labs .... Displaytech ... Distributed Energy Systems ... Divergence ... Diversified Energy ... D. Light ... DMC Biotechnologies ... DNAnexus ..... DNAPrint Genomics ... DNAtrix .... DNV GL .... Dova Pharma ..... DoX Systems ... Dracen Pharma ..... Dragon Systems .. Dragoon ITCN ..... Drilling Info ... DrillMap .... DropWise .... DR Technologies ..... DrugCendR .... DSM .... DT Solar ... DuBay Ingredients ... duPont Aerospace ... Dura Biotech .... Durata Therapeutics ... Durin Technologies .... DVS Sciences .... DxUpClose .... Dyadic International ..... Dyax ...DynaBil Industries ... Dynasil ... Dynavax Technologies ... Dyne Thrapeutics ... Dynetics .... Dynogen Pharmaceuticals

E3 Clean .... Eagle Optoelectronics ... Earl Energy .... EarLens .... Earth Networks .... Earthrise Nutritionals ... eASIC ..... Eboo Pharmaceuticals .... EBR Systems ..... Ebullient .... Echelon .... Echodyne ..... Echometrix ... EchoPixel ..... Echo Therapeutics (was Sontra)... ECI Biotech ... ECM Technologies ..... Ecocurrent ... EcoPesticides .... EcoPro Polymers ..... Eccrine Systems ..... Ecovative Design ... Edaptive Computing .... Eden Bioscience ... Edenspace Systems ... Edge Therapeutics ..... Edico Genome .... Edison Agrosciences ..... Editas Medicine .... EEStor ... Effector Therapeutics .... Egalet .... eGenesis .... Eiger BioPharmaceuticals ..... Eikos ... E-Ink ... EIS .... Ekos ... EKR Therapeutics .... Ekso ... Elcelyx Therapeutics ... Electrical Geodesics ..... ElectroCell Technologies ... ElectroChemical Systems ... Electro Energy ...Electromed ... Electro Optical Sciences ... Electro Scientific ... Electrozyme .... Elementary Robotics .... Elemetric Instruments ... Elevation Pharmaceuticals ... Eleven Biotherapeutics ... Elira Therapeutics ..... Elixir Biopharm ... Elixirgen Therapeutics ..... Elixir Pharmaceuticals ... Ellipse Technologies ..... Elon ... Elstar Therapeutics ..... eMagin .. Embera NeuroTherapeutics .... Embodied .... EmboMedics ..... Embrex .. EMCORE ... Emerald BioStructures .... Emergent BioSolutions ... Emergent Technologies ... EM Photonics .... Empire Genomics .... Empire Robotics .... EMRes Technologies ... Emtora Biosciences (formerly Rapamycin Holdings) .... Emulate .... Enable Injections ...... Enanta Pharmaceuticals ..... EnChroma ..... Encite ... Encoded Genomics .... Encompass Bioscience ..... Encore Vision .... Encysive Pharmaceuticals ... Endeavor Robotics ..... Endece ... Endgame Technologies ... EndoChoice .... Endocyte ... EndoGastric Solutions ... Endo International ..... Endoscopic Technologies ... Endosee ..... EndoStim .... Endotherapeutics ..... Ener1 ... EnerG2 ... Energen ... Energesis Pharmaceuticals .... Energetiq Technology ... Energid Technologies ... Energous ..... Ener-G-Rotors ... Energy Control ... Energy Conversion Devices . .. Energy Focus ..... Energy Recovery ... Energy Solutions ... Energy Storage Systems ..... EnerMat Technologies ..... EnerMed ..... Enertech Environmental ... EnerVault ... Engineered BioPharmaceuticals .... Engineered Propulsion ...Engineous Software ... Enlibrium ..... Enlight Bioscience ... EnSync Energy Systems (formerly ZBB Energy) ..... Ensysce Biosciences ... Entasis Therapeutics ..... Entech ... Entegrion ... Entellus Medical ..... Entera Biotech .... Entergem Ventures .... EnteroMedics ... Entia Biosciences ..... Entira Bio .... Entopica Therapeutics ... EntreMed ... Entrada Therapeutics ..... Entra Pharmaceuticals ... ENTrigue Surgical ... Envia Systems .. Entrotech Life Sciences ..... Entvantage Diagnostics ..... EnviroFlight ..... Envisia Therapeutics ..... Envistacom .... EnVivo Pharma ... Enzenia ... Enzium ... Enzo Biochem ... Enzymatics ... EnzyMed ..... Enzyvant ..... EO2 Concepts .... EOIR ... Eonix .... EpiBiome .... EpiBone .... Epicentre Biotechnologies .... Epic Sciences .... Epic Systems ..... Epicypher .... EpiEP ... Epion ... Epiphany Solar Water Systems .... Epitomics ... Epiva Biosciences ..... EpiVax ... EpiWorks .... Epix Pharmaceuticals ... Epizyme ... Eppin Pharma .... EqualLogic ... Equex ... Equillium .... Equipment Concepts ... EraGen Biosciences ... Erallo Technologies ... Erasca .... Ercole Biotech ... ERT ..... Escalier Biosciences BV ..... Escalon Medical .... E-Scape Bio ..... Escient Pharmaceuticals ..... Escoublac .... eScription ... eSolar ... Eso-Technologies ... Esperance Pharmaceuticals ..... Esperion Therapeutics ..... Essential Biotechnology ..... Essential Medical .... Essentient .... Essex... Eta Devices ..... Eta-Gen .... Etegent Technologies ... E-Tek Dynamics ... Euclid Labs .... Euclises Pharmaceuticals ..... Eureka Therapeutics ..... Euthymics Bioscience ... EVapt .... Evelo Therapeutics .... Evena Medical ..... Ever Cat Fuels ... Evergen Biotechnologies ... Evergreen Solar ... Everspin Technologies .... Evestra .... Evident Technologies ... Evofem Biosciences .... Evoke Pharma ..... Evolution Robotics ... Evolv .... Evolve BioSystems ....EWI .... Exact Sciences .... Exagen Diagnostics ... Excelimmune ... Excel Technology .... Excision BioTherapeutics ..... Exelixis ..... Exelixis Plant Sciences ... Exemplar Genetics .... Exo ..... Exogenesis ..... Exone .... Exosome Diagnostics ..... Exovita Biosciences .... ExploraMed NC4 ... Expression Analysis .... Exquadrum .... Exsulin ....Extreme Molding ... Extremity Innovations ... EyeGate Pharmaceuticals ... EyeNetra .... EyeTel

Fallbrook Technologies ... Famigo ... Faraday Pharmaceuticals .... Farodox Energy Storage ... FarSounder ... Far-Tech.... FastCAP Systems ... Fate Therapeutics ... Fathom .... Fe3 Medical .... FEI ... Femasys .... Femta Pharmaceuticals .... Ferrate Treatment Technologies ... Ferric Contrast ...... FerroKin BioSciences .... Fervo Energy .... Feuz Manufacturing ... FGC Plasma Solutions ..... Fiber and Sensor .... Fiberight ... Fiber Materials ... Fibersense ... Fiberstar .... Bio-Ingredient Technologies ... Fibertek .... Fibrocell Science ... FibroGen ... Filter Sensing Technologies ... Finally Light Bulb ..... Finch Therapeutics Group ..... FineLine Prototyping .... Finisar ... Fire Alarm Specialty Design ..... Firefly BioWorks ... Firefly Energy .... Firefly LED ... First Solar ... Fisker Automotive ... Five Prime Therapeutics .... Flex Biomedical ... Flexion Therapeutics ... Flex Pharma .... Flextronics America .... Flexus Biosciences .... FLIR Systems .. FloDesign Wind Turbine ... FlowCardia ... FlowMedica .... FlowMetric .... Flow Metrix ... FluGen ... Fluidic Energy ... Fluidigm ... Fluid Innovation Group ... Fluidnet ... Fluidnet FluoroPharma ... Fog Pharma ..... Foghorn Therapeutics .... FokusLabs .... FoldRx Pharmaceuticals ... Follica ... Footnote .... Foresight Biotherapeutics .... Forest Devices .... Forge Therapeutics ..... F-Origin ... Forma Therapeutics ... Formlabs .... For-Robin ..... ForSight Vision5 .... Fortis Therapeutics ..... Forty Seven ..... Forum Pharmaceuticals ..... Forus Health ... Foster-Miller .... Foundation Medicine ... Fox Chase Chemical Diversity Center .... Fractal Antenna Systems ... Fractyl Labs ..... Freedom Meditech ... Free Flow Power ... Free Form Fibers .... Freenome ..... Froedtert Health ..... Frontier NanoSystems ..... Frontier Technology ..... Front Range Biosciences .... FTL Solar ... FuelCell Energy ... Fuel Tech .. Fulcrum Therapeutics ..... Fulgent Therapeutics ..... Full Spectrum Genetics .... Furiex .... Fused Innocation. ... Fusion Coolant Systems ... Future Technologies

G1 Therapeutics ..... G3 .... Gadusol Laboratories (aka Seaceuticals) ..... Galderma .... Galectin Thera ..... Galenea ... Galena Biopharma .... Galera Therapeutics ..... Galil Medical ..... Galleon Pharmaceuticals ... GAM Enterprises .... GameSalad ... Gamma Medica Ideas ... Garland Technology ..... Garwood Medical Devices ..... GATR Technologies ..... G-Con .... Gecko Biomedical .... Gecko Robotics .... Gel Combs .... Gelesis ... Geltech ... Gema Diagnostics .... GEMFIRE .. Gemin X Pharmaceuticals ... Gemmus Pharma ... Gemneo Bioscience ..... Gemphire Therapeutics ...... Gemstone Biotherapeutics ..... Gen9 ... Genaera ... Genalyte ... Genapsys .... GenAudio .... Gene by Gene .... GeneCentric Diagnostics ... Genelabs Technologies ... Gene Logic ... Geneoscopy ..... General Compression ... General Pneumatics ..... Generation Bio ..... Generex Biotechnology ... Gene Security Network .... GeneSegues Therapeutics ..... GenesisLabs .... GeneSystems ... Genetesis .... Genetic Networks ..... Genetix Pharmaceuticals ... GeneTx Biotherapeutics ..... Geneu .... Genia Technologies .... GenMark Diagnostics .... Genoa Pharmaceuticals ..... Genocea Biosciences ... Genomatica ... Genome Profiling ... GenomeQuest ... Genomic Health ... Genomind .... Genoptix Medical Laboratory ... Genor ... Genprex .... Gen-Probe ... GenSpera .... GenTel BioSciences ... Gentris ... GenturaDx ...nbsp; GenVec ... GenWay Biotech ..... Genzyme .... Geocent .... Geocove ..... Geomagic ... GeoMed Analytical ... GeoVax Labs ... Geospiza ... Germfalcon ..... Geron ... Gevo ..... GI Dynamics ... GigOptix ... Gilead Sciences .... Giner . .. Ginkgo BioWorks .... Glauconix ..... Glaukos .... GlideLine Systems ... Gliknik ... Global Blood Therapeutics ...... Global Cancer Diagnostics ..... Global Positions ... Global Blood Therapeutics .... GlobeImmune .... Gloucester Pharmaceuticals ... Glowforge ..... GlucaGo ... GlycoFi ... GlycoMimetics .... GlyGenix ... Glympse Bio .... Glyscend ..... GlySens ... GMZ Energy ... GnuBio .... Goddard Labs .... Goldfinch Bio ..... Good Start Genetics .... Gore Photonics ... Gossamer Bio ..... Gotham Biotech .... Gotham Therapeutics ..... GPC-Rx ... gRadiant Research ... Gradiant .... GraftWorx ..... Grail ..... Graphene Energy ... Graphenix Development .... Graphic Surgery ... GraphLab (now Dato) .... Grassroots Biotechnology ... Greatbatch ... GrayBug ..... Graybug Vision ..... Great Basin Scientific ..... GreatGrow Maryland .... GreatPoint Energy ... Green & Grow .... GreenFuel Technologies .... Greenlight Biosciences .... GreenMark Biomedical ..... Green Mountain Radio Research .... GreenSight Agronomics ..... Green Sulfcrete ..... GreenTech America ... Greenwich Geriatrics .... GridBridge .... Grid Therapeutics ..... Gritstone Oncology ..... GRO Biosciences ..... Group14 Technologies ..... Grove Instruments ... Grow Home Organics .... GSI Technology ... GT Advanced Technologies ... GTC Biotherapeutics ... G-Tech Medical .... GT Equipment .... GTI Diagnostics ... GT Medical Technologies ..... GTx .... Guardant Health .... Guided Surgery Solutions .... Guided Therapeutics .... .... Guided Therapy Systems ..... Gynesonics ..... G-Zero Therapeutics

2 Energy Now ...... H2O Score ..... H2Pump ... H2Sonics .... H3 Biomedicine ... HNC Software ... Halozyme ... Hana Biosciences .... Hansen Energy and Environmental .... Hansen Medical ... Haplogen Genomics ..... Harbor Technologies .. Hardcore Computer ... HarkerBio .... Harmony Enterprises .... Harpoon Medical .... Harpoon Therapeutics .... Harvard Apparatus Regenerative Technology .... Harrisvaccines .... Harvard Bioscience ... Harvest Automation .... Harvest Power ... Harvest Technologies .... Healionics .. Health Diagnostics Laboratories .... HealthMyne .... Healthtronics .... Hearforward ... Heartland Robotics .... HeartWare International ... Heat Biologics .... ... HeatGenie ... Helicos BioSciences ... Helion Energy .... Heliovolt ... Helius Medical Technologies ..... Helix Therapeutics ... Helomics (formerly Precision Therapeutics) ..... Hemadvance ..... HemaQuest Pharmaceuticals ... Hemarrest ... Hemera Biosciences .... Hemispherx Biopharma .... HemoGenyx .... Hemoshear Therapeutics ..... HemoSonics..... Hemostasis ... Hennepin Life Sciences .... Hepregen ... Heraeus Medical Components .... Herley Industries ... Hermes Biosciences ... HexaTech .... Hexfuel .... Hibernaid .... Highbury Defense Group .... High Impact Environmental .... High Performance Technologies ... High Point Pharmaceuticals ..... Histogen .... HighRes Biosolutions .... Histogenics ... HistoRx ... HistoSonics .... HJM Precision ..... HocusLocus ..... Hoku Scientific ... Holaira .... Hollingsworth & Vose .... Hollis-Eden Pharmaceuticals ... Holomni .... Homology Medicine ..... Honeycomb Batteries .... Hontek ... Hookipa Pharma .... Hoopers Island Oyster Aquaculture ... Hoppe Tool .... Hoth Therapeutics ..... Howe Industries .... Hsiri Therapeutics ..... HTG Molecular ..... HTSS ... Humacyte ... Humanetics ..... Human Genome Sciences ... Human Metabolome Technologies .... HuTerra .... Huya Bioscience International .... Hybritech ..... Hybrivet .... HYCOR Biomedical ... Hydra Biosciences ... HydroCision ... Hydrogen Safety ... HydroLogic Industries .... Hygeia Therapeutics ... HyperBranch Medical Technologies ... Hyperion Therapeutics ... HyperMed ... HYPRES .. Hy-SyEnce ... HyTrust

IAP ... IBC Advanced .... iBiquity Digital ..... Ibis .... Iblogix .... IBT Laboratories ... Icagen .... Icardiac.... Ichor Medical Systems .... Iconic Therapeutics ..... Icos.... ICX.... Idaho.... Ideal Converters ... Ideapaint.... Ideaya Biosciences ..... Idera Pharmaceuticals ..... ID Genomics .... Idevices ... IDx ..... iFirst Medical Technologies ...... IFM Therapeutics ..... Igenica Biotherapeutics .... Ignyta.... Ii-IV .... Ikaria... Ikonisys... Illinois Superconductor.... Illumigen.... Illumina.... Illuminating Diagnostics ..... Illuminoss.... Illumitex.... Imagen Energy .... Imagevision.... Imaging Biometrics... Imagineoptix ... Imago Instruments... Imanis Life... Imbed Biosciences... Imetalx... Immco... Immersion... Immtech... Immucell .... Immucor .... Immune... ... Immune... Immune Pharma .... Immunetics... Immunex... Immunexcite... Immuneworks... Immunexpress ..... Immunicon... ImmunoCellular Thera .... ImmunoChemistry Technologies ..... Immunocore... Immunogen... Immunome ..... Immunomedics..... Immunomic Therapeutics ..... Immunophotonics ... Immurx... .... Immusant... Immusoft ..... Impact Biomedicines .... Impact Proteomics .... Impact Science... Impel Neuropharma... Imperium Renewables... Impinj... Implant Sciences... Impossible Foods .... Imprimis Pharmaceuticals .... Imprint Energy .... Impulse Monitoring ... Imricor Medical Systems ..... Imris ..... Imthera... I-nalysis ... Inari Agriculture .... InCarda Therapeutics .... INCELL .... Incelldx ..... Incitor (now XF Technologies) .... Incodema3D ..... Incontrol Research... InCube Labs ..... Incyte ....Incytu... Indalo Therapeutics ..... Indiana Nanotech... Indi Molecular ... Industrial Heat ..... Industrial Perception... Inentec ... InfaCare Pharmaceutical .... Infarct Reduction Technologies .... Infinera... ... Infinia... Infinity... Infinium .... Inform Genomics... Infoscitex... Inframat... Infraredx... Infrascan... Inf Robotics ... Infusion Medical ... Ingeneus... Ingeneron ..... Inhibitex... Inhibkase Therapeutics .... INI Power... Inland Labs ..... Inmobly .... InnAVasc Medical .... Inneroptic... Innerpulse... Innocrin Pharmaceuticals ..... Innography... ... Innopad... Innotec ..... Innovalight... Innovari Energy Design Microplate Scientific... pulmonary solutions.... silicon... Innovate Biopharmaceuticals ..... Innovative Spinal... Innovative... Innoventiontech ... Innovention (now Ccardiorobotics) ... Innovative Trauma or... Innovolt ... Innowave... ... ... Innoviva ... Innov-x... Inocucor ..... Inorganic Specialists... Inotek... Ino .... Inova Labs Biomedical... Inovio... Inovise Medical ..... Inozyme Pharmaceuticals ..... Inphase... ... Inphi... Inpria ..... Inscripta ..... Insert MRI... Insight... ..Insite Vision...... Insitu... InSitu Biologics ..... Insmed... Inspired Solar Systems ... Inspire... Insulet Labs ... Intact Vascular... Intaglio... Intalio ... Intarcia Therapeutics ... Integenx... Integra Group Diagnostics... Integral Molecular ..... Integrated BioTherapeutics .... Integrated Diagnostics .... Integrated Diagnostics InDi .... Integrated DNA Technologies ..... Integrated Fuel... ... Integration Associates... Intelect Medical Intelleflex ... Intellia Therapeutics ..... Intellicyt Automation Bio-systems ... Intelligent Devices .... Intelligent Epitaxy Technology ..... Intellimedix ..... Intelliphage.... Intellirad Control... .Intellisense .... Intelomed ....Inter-4... Interactive Supercomputing ... Interdigital Interlace .... Intermagnetics General ...Intermolecular ... Intermune.... International Stem Cell ... Interrad Medical ..... IntersectENT .... Intersense... Intersystems ... Intervalve.... Intevac.... Intra-Cellular Therapies ..... Intralase ...... Intralytix .... Intrexon ..... Intrinsic Therapeutics .... Intrinsity.... Introgen.... ... Intuitive Biosciences .... Intuitive Genomics ..... Intuitive Surgical.... Invenra .... Invensense .... Inventev ..... Inverness Innovations.... Invirsa ..... Invertix.... Invictus.... Inview Technology.... Inviragen.... Invisage Technologies .... ....InvisionHeart .... Invision Medical .... Invitae.... Invitrogen.... ...Invivosciences.... Invivo Therapeutics= Holdings .... Invuity.... Inx Medical.... IoGyn .... Iomai.... ... Iomed.... IOmet Pharma ..... Ion America Optics..... Ionic Materials ..... Ion Torrent.... Iovance Biotherapeutics ..... Iovation.... Iowa Thin Film.... Ipierian.... IPG Photonics.... ... Iquum ...Irhythm... iRobot... Iroko...Ironbridge.... ... Ironwood.... ... .... Irvine Sensors... .... biopolymer . .... Ischemia Care.... iSee ..... iSIGHT Partners ..... Isis.... Island Ddata.... Isogenis.... Isomark.... IsoPlexis .... Isoray.... Isothermal.... Isthmus Biosciences ..... IstoTechnologies.... itaconix.... I-Therapeutix..... Itherxm Pharmaceuticals.... Itraumacare... .. Itseez ..... Itzbig ..... Iwalk

Jade Therapeutics ..... J&Y ... Janssen Biotech .... Janus Biotherapuetics ... Javelin Pharmaceuticals ... Javelin Semiconductor ... JDP Therapeutics ..... Jennerex ... Jnana Therapeutics ..... Joule Biotechnologies .... Jounce Therapeutics .... Joyent .... Joylux .... Juno Therapeutics ..... Just Biotherapeutics

K2M .... K2 Therapeutics .... KAER Biotherapeutics .... Kala Pharmaceuticals ... Kaleido Biosciences ..... Kallyope ..... KaloBios Pharmaceuticals ..... Kalocyte .... Kalon Biotherapeutics ..... KalVista Pharmaceuticals .... Karius ..... Karuna Therapeutics ... Karyopharm Therapeutics ... Kateeva ..... Kayo Technology ..... KaZaK ... KC BioMediX ... KCI .... KDH Defense Systems ... Kebotix .... Keithley Instrument ... Kelyniam ... Kenall Manufacturing ..... Kensey-Nash ... Kent Displays ... Kentucky BioProcessing .... KeraNetics .... Keros Therapeutics ..... Kezar Life Sciences ..... KeyW .... Kilawatt Technologies ... Kindara .... KinDex ... KindHeart ..... KineMed .... Kinestral Technologies ..... Kineta ... Kinetic Concepts .... Kinex Pharmaceuticals .... Kingbright .... Kior ..... Kips Bay Medical ... Kite Pharma ..... Kitware ... Kiva Systems ... KLD Energy Technologies .... Klotho Therapeutics .... KMel Robotics .... Knightscope ..... Knome ... Knopp Neurosciences .... KNOW Bio ..... Know Labs .... KnuEdge .... Koam Engineering Systems .... Kodiak Sciences .... Kolltan Pharmaceuticals ... Komoku ... Kona Medical .... Konarka ... Koning ... Kopin .. KOR Electronics ... Koronis Pharmaceuticals ... Kosan Biosciences ... Kosmetikos .... Kovio ... KPI Therapeutics (from Kineta)... Kraig Biocraft ..... Kratos Defense & Security Solutions .... Kronos Advanced Technologies ... Krystal Biotech .... KSE ... KSQ Therapeutics ..... Kultevat ..... Kura Oncology .... Kumu Networks .... KVH .. Kylin Therapeutics ... Kyma ....Kymera Therapeutics ..... Kymeta ... Kyn Therapeutics .... Kyocera Solar .... Kypha ..... Kyras Therapeutics ..... Kyron Clinical Imaging .... Kytopen

LAAMScience ... LaBelle Associates ..... LabNow ...Laborie Medical Technologies ... Labrys Biologics ... Lacerta Therapeutics ..... Lactic Solutions ..... Laguna Pharmaceuticals (formerly ChanRx) ..... La Jolla Pharmaceutical ... Lake Shore Cryotronics .... Landec .... Landos Biopharma .... Lantern Pharma ..... Lantheus ... Lantos Technologies ... Lariat Biosciences .... Laser Design .... Lasergen ..... LaserMax ..... LaserMotive ... Laser Tissue Welding .... Lattice Biologics ..... Lattice Biotech .... Lawrie ... Lazarus Effect ..... LDR Holding ..... Lead Therapeutics ... LeafBio .... LeCroy ... LED Lighting Fixtures ... Lehigh Technologies .... Leica Microsystems ..... LetoSolutions .... Lexicon Genetics ... Lexicon Pharmaceuticals ... Leyden Energy ... Libra BioSciences .... LifeCell ... LifeGen Technologies ... Life Image ... LifeMine Therapeutics .... LifeSprout .... Life Technologies .... Ligand Pharmaceuticals ....Ligon Discovery ... Lightpointe ... Light Sciences Oncology ... LightWorks Optics .... Lilliputian Systems .... Lily Robotics ..... Linares Management Associates .. Lingotek ... Linnaeus Therapeutics .... LinQuest .... Lionano .... Lion Biotechnologies ..... Lipocine .... LipoScience ... Liquid Biotech ..... Liquidia Technologies ... Liquid Light ... Liquid Metal Battery ... LiquidPiston ... Liquid Robotics ... Liquid X Printed Metals .... LiQuifix ... Lithium Technology ... LiveData ... . LiveLeaf Bioscience .... LKC Technologies ... Locus Biosciences .... Lodo Therapeutics .... Logical Therapeutics ... LogicBio Therapeutics ..... Logos Tech ... Lohocla Research ..... Lombard Medical ..... Longeveron ..... LonoCloud ..... Lookingglass ..... Loon Medical ..... Lotus Tissue Repair ... Loxo Oncology ... LPath Thera .... Lq3 Pharmaceuticals .... LS9 ... Luca Technologies .... Lucerno Dynamics .... Lucidux ... Lucigen .... LumaSense Technologies .... Lumena Pharmaceuticals .... Lumen Bioscience .... Lumencor ... Lumense .... Lumera ... Lumicell Diagnostics ... Luminary Micro ... Luminex .... Luminus Devices ... Lumisyn ..... Lumitex ... LumiThera .... Lumos Pharma .... Luna Innovations ... Luna Technologies ... Lung Therapeutics .... Lutonix ... Luxtera ... Lycera ... LyGenesis ..... Lyncean ..... Lynntech ... Lynx Biosciences ... Lyra Therapeutics ..... Lysosomal Therapeutics .... Lytro Therapeutics

M3 Biotechnology .... MabVax .... MacAulay-Brown ..... Macrochem ... MacroFab ..... Macrogenics ... Macrolide Pharma ..... Macrophage Therapeutics .... Madison Vaccines .... Madrigal Pharmaceuticals ..... MagBioSense ..... Magenta Therapeutics ..... Magic Leap ..... MagneMotion ... Magnesium Development ..... Magnetek ... Magnolia Medical Technologies .... Magnolia Optical Technologies ... Magnolia Solar ... Mainstay Medical International ...... Mainstream Engineering ... Major Pharmaceuticals .... Mako Surgical ... Manhattan Scientifics ..... Mantra Bio ..... >Manufcturing Techniques ..... MapInfo ...MAP Pharmaceuticals ... Mapp Biopharmaceuticals .... Marathon Pharmaceuticals ..... Marcadia Biotech ... Marina Biotech ... Marinus Pharmaceuticals ... Maritime Applied Physics .... Marrone Bio Innovations .... Martek Biosciences ... Mascoma ... Mashery ... Mason Box ... Masten Space Systems ... Masterson Industries .... Mast Therapeutics (formerly ADVENTRX) .... Material Sciences ... Material Technologies ... MathStar ... Mati Therapeutics .... Matouk Textiles ... Matritech ... Matrix Product Development .....Matrix Research .... Matrix Sensors ... Maverick Therapeutics .... MAX BioPharma ... MaxCyte ...... Maxdem ... Maxpower ... Maxygen .... Maze Therapeutics .... MBio Diagnostics .... MC10 .... MCube .... M Cubed Technologies .... MD Biosciences ..... MDSolarSciences ... Mebias Discovery ..... Mechanical Technology ... Mechanology ... Medafor ... Medarex ... MediBeacon .... Medicago USA .... Medical21 ..... Medical Cyberworlds .... Medical Device Logistics ... MedicaMetrix... Medgenics ..... MediciNova ..... Medicool Technologies .... MedImmune .. Medina Medical .... Mediomics .... Medior Therapeutics .... Medis ... MEDITE Group .... Medivation ... Mednology Solutions .... Medrobotics ... MedShape .... MedSocket (formerly 1CDS) ...... Medsphere Systems ..... MedTel ..... MEI Pharma ..... Meka .... MELA Sciences .... Melinta Therapeutics .... Melior Discovery .... Memjet ...Memry ... Memsic ... MEMS Optical...Menlo Therapeutics ..... MER ... Mercator Therapeutics ... Mercury Computer Systems .... Merganser Biotech .... Merge Technologies ... MeriaGTx ..... Meridian Bioscience ... Meritage Pharma ..... Merkatum ... Merrimack Pharmaceuticals ... Meryx .... Mersana Therapeutics ... Mesa Photonics ... Mesocopic Devices ... Metabasis ... Metabiota .... Metabolic Solutions Development .... Metabolex .... Metabolix ... MetaCarta ... Metacrine .... Metactive Medical ..... Metal Oxygen Separation Technologies ... Metamark Genetics ... MetaModix ... Metavention ..... Metompkin Seafood .... MetroLaser ... MGC Diagnostics ... MIACH Orthopaedics ..... Misaole .... Micell Technologies ... Michelman ... Micracor .... Micrel ... MicroCoating ... Micracor .... Microbe Detectives ... Microbia ... Microbot Medical ... Microfluidics International (Microbia) ... MicroGreen Polymers .... MicroIslet ... Microlin Bio .... MicroMask ... Micronics ... MicroOptical (New Mexico)... MicroOptical (Massachusetts) ... MicroOptx ..... MicroPower Technologies ... MICROrganic Technologies .... MicrowSat Systems .... Microscopy Innovations ..... Microstaq ... MicroTransponder ..... Microvision ... MicuRx Pharmaceuticals .... Midori Renewables ..... Mid Valley Industries ... Millendo Therapeutics (born as Attercor) ..... Million Concepts ..... Miltec .... MiMedx Group .... MimiVax .... Minerva Biotechnologies ... Minerva Neurosciences .... Minerva Surgical .... Minimally Invasive Devices .... Minnesota Thermal Science ..... Minnetronix ... MIOX ..... Mirador Biomedical ... Mira Dx ... MiRagen Therapeutics ..... Miramar Labs .... Mirati Therapeutics ..... miRecule .... Mirimus ... Mirina ... Mirna Therapeutics.... Miromatrix Medical ... Mirus Bio ....Mirum Pharmaceuticals ..... Mission Bio ..... Mission Research ... Mississippi Polymer ... Mithridion ... Mitochon Pharmaceuticals ..... Mnemosyne Pharmaceuticals ... Mobile Robots ... Mobius Therapeutics ..... Moderna Therapeutics .... Modern Meadow .... Modern Technology Solutions .... Moduline Systems .... Modumetal ..... MOgene Green Chemicals .... Molecular Biometrics ... Mohawk Innovative Technology ..... Molecular Detection ... Molecular Diagnostics .... Molecular Imprints ... Molecular Insight Pharmaceuticals ... MolecularMD ... Molecular Sensing ... Molecular Templates .... Moleculin Biotech ..... Molten Metal .. MoMelan Technologies ... Momenta Pharmaceuticals ... Monebo ... Monogram Biosciences .... Monteris Medical ..... Morphic Therapeutics ..... Morphormics ... Morphotek ... Morris Innovative Research ... Mortara Instrument ... MortaSecurity .... Motif ... Motricity ... Motus Therapeutics .... Mound Laser & Photonics Center ..... Movia Robotics ..... Moximed .... MPP Group ... MPSP ... MSNW .... Mudawar Thermal Systems ..... Munksjo Paper ... Muons ... Muse bio .... Myco Technology .... Myocor ... MyoKardia ... Myomo ... Myonexus Therapeutic ..... Myovant Sciences ..... Myriad Genetics ... Myriant Technologies ... Mystic Pharmaceuticals

N12 Technologies ... (N30 Pharmaceuticals) now Nivalis Thera .... NABsys ... Nalas Engineering .... Nammi Therapeutics ..... NanOasis Technologies ... NanoBio ... Nanobiosym ... Nano-C ... NanoCellect (formerly NanoSort) ..... Nanocomp Technologies ... NanoCoolers ... Nanocopoeia ... NanoCor Therapeutics ...Nanodynamics (Buffalo) ... Nano DX ..... Nanodynamics (NYC)... NanoeXa .... Nanofiber Solutions ... Nanogen ... NanoGraf (formery SiNode) ..... NanoGram .... nanoGriptech ..... NanoGuard Technologies .... NanoH2O ... Nanohmics ... NanoLab ... NanoLite Systems ... NanoLogix ... NanoLumens ..... Nanomaterials Research ... NanoMatrix ... NanoMedex ... NanoMedicalSystems ... NanoMedical Systems .. Nanomix ... nanoMR ..... Nanophase Technologies ... NanoPhotonica ... Nanopore Diagnostics ..... Nanoptek ... Nanoramic Laboratories (formerly FastCap Systems) ..... nanoRETE .... Nanoscale Components ... Nanoscale Materials ... Nanosolar ... Nanosonic ... Nanospectra Biosciences .... Nanosphere ... NanoSteel ... Nanostim .... NanoString Technologies .... Nanosys ... NanoSystems ... Nano Tailor ... Nanotek Instruments ..... Nano-Terra ... Nanotherapeutics ..... NanoTune Technologies ... Nanova .... Nanovation Technologies ... NanoVault Medical .... NanoViricides ... NanoVision Diagnostics .... NantCell ..... Nantero ... Napo Pharmaceuticals ... NantKwest ..... Narus Biotechnologies ..... Nascentric ... Nastech Pharmaceutical ... Natera .... National Technical Systems ..... Natural Molecular Testing ..... NaturalNano ... Nature's First ..... Natus Medical ... Naverus ... Navidea Biopharmaceuticals ... Navini Networks ... Navire Pharmaceuticals .... Navitor Pharmaceuticals .... Navmar Applied Sciences ... NBD Nanotechnologies ....NCD Technologies .... nContact Surgical ... Neah Power ... Near Infinity .... Neato Robotics ... Nektar Therapeutics ... Nekton Research .... NemaMetrix .... NeoChord ... Neogen .... NeoGenomics ..... Neograft ..... NeoLight ..... Neon Therapeutics .... NeoPhotonics ... Neoprobe ... Neos Therapeutics ..... NeoSync ..... Neothetics .... Neotron ... NephroGenex .... Nereus Pharmaceuticals ... Nest .... Netcentric .... Netezza ... NetLogics Microsystems... Netspeed Systems ...... Net Watch Solutions ..... NetworkFab ... NeurAccel Biosciences ... Neurala .... Neural Analytics .... Neuralstem .... Neuraly ..... Neuraptive Therapeutics ..... Neuro Amp .... Neurobiological Technologies ... NeuroChaos Solutions .... Neurocrine Biosciences ... NeuroDx Development ... NeuroEM .... Neurodyne Medical ... Neurofluidics ....Neurogastrx .... Neurogen ... NeurogesX ... Neurognostics .. NeuroHabilitation .... NeuroLogica .... NeuroLutions ..... NeuroMap ... Neuro Kinetics .... NeuroMetrix... Neurona Therapeutics .... Neuronetics . Neuronex .. NeuroOne ..... NeuroPace ... NeuroPhage Pharmaceuticals ... Neuron Systems ... NeuroPointDX ..... Neuroptix ... Neuroscience .... NeuroSigma .... NeuroTek .... Neurotrack .... NeuroTronik .... Neurotrope ..... Neurovance ... NeuroVigil ... Neurovascular Diagnostics ..... NeuroVision Imaging .... NeuroVista .... NeuroVive .... NeuWave Medical ...Nevro ... New Dominion Enterprises ..... NewLeaf Symbiotics .... NewLink Genetics .... Newlink genetics england ... biolabs ... new era technology ... New Haven Pharmaceuticals ... Nexant ...Nexbio ... NexImmune .... NexPlanar .... NextCODE Health .... NextCure ..... Nextio .... NEXTracker ....Nextreme Thermal Solutions ... NextStep Robotics ..... Nexus Biosystems ..... NG1 Technologies .... NGM Biopharmaceuticals .... Nico ..... Night Vision ... Nimblegen Systems ... Nimble Storage .... Nimble Therapeutics .... Nimbus Discovery ... Nimbus Therapeutic ..... Ninepoint ...Niowave ... NIRvana Sciences .... Nitero.... Nitric Biotherapeutics ....Nitricgen ... Nitride Solutions .... Nitrogenics ..... Nitromed ...Nitronex ... Nivalis Therapeutics formerly N30 Thera ..... NKT Therapeutics ... Nlight ... NMT Medical .... Noah Technologies .... Noble Fiber ... Nocion Therapeutics .... Nohla Therapeutics .... Noivatone .... Nok Nok Labs .... Nomadics .... NONA Composites .... Noninvasix .... Nonvolatile Electronics .... Nora Therapeutics .... Norian ... NorMedix ..... Normoxys .... Norse .... Northeast Photosciences ... Northstar Medical Radioisotopes .... Northstar Photonics... Northwest Biotherapeutics .. Norwich Technologies .... Nostopharma .... Notice Ttechnologies ... .Novacea ... Novalar Pharmaceuticals ... Novalux ... Novan Therapeutics .... NovaScan ... Nova Synthetix .... Novatek ... NovaTorque ... NovaTract Surgical ... Novavax .... Novazyme Pharmaceuticals ..... Novecon Technologies ... Novella Clinical .... Novelos Pharmaceuticals ... Novelos Therapeutics ... Noveome Biotherapeutic ..... Novian Health .... Novira Therapeutics ... Novocell ... Novogy ... Novomer ... Novophage ... Novo Sol-u-tions MD .... Novosource ... Novozymes .... Novus Biologicals .... Noxilizer ... Nox Technologies ... NP Photonics ... NPS Pharma ..... NRGindependence ..... NSS Labs ..... Nucelis .... Nuclea Bioechnologies ... Nufern .... NuGEN Technologies ..... NuMat Technologies ..... NuMedii .... NumereX .... NUMiX Materials ..... NuPathe .... Nurel (now PeriphaGen) .... Nuron Biotech ... Nutrabiotix ... Nutrient Recovery and Upcycling .... NuVant ... Nuvaira .... NuVascular Technologies .... Nuve ..... Nuventix ... Nuvera Biosciences ... Nuvera Fuel Cells.. . Nuvotronics ..... Nuvox Pharma ..... Nu Waves ..... NxThera ... Nvision Biomedical Technologies ..... NZ Applied Technologies

Oak-Mitsui .... Oasys ... ObjectVideo ... Obsidian Therapeutics ..... OBS Medical ... Ocarina Networks ... Ocata Thera ... Occipital .... Ocean Power Technologies ... Ocean Renewable Power .... Ocera Thera .... OCI ... Ocugen ..... Ocular Therapeutix .... Oculeve ... Oculogica ..... Oculus ... Oddpost ... Odyssey Systems Consulting Group ... Oil Chem Technologies ... OLEDWorks .... Omeros ... OmniGene Bioproducts ... OmniGuide ... OmniLytics ... Omniox ..... OmniSonics Medical Technologies ... Omnis PharmaRebiotix .... Omni Water Solutions ... Onboard Dynamics .... ONCE Innovations ..... OnChip Power .... Oncobiologics ..... OncoCyte .... Oncogenex ... Oncolmmune ..... Oncolinx .... Oncolix ..... Oncolytics Biotech ... OncoMed Pharmaceuticals .... OncoNano Medicine .... Onconova Therapeutics ...Oncoscope ... OnCore Biopharma ..... OncoResponse ..... Oncorus ..... OncoSec Medical .... OncoTartis ...... Oncothyreon ... Oncovista Innovative Therapies ..... Oncternal Therapeutics ... Onduo ..... One Resonance Sensors .... Onexio Biosystems .... Onko Solutions .... ONL Therapeutics .... On-Q-ity .... Onspira Therapeutics .... On Target Laboratories .... Ontela ..... On-X Life Technologies .... Onyx Pharmaceuticals ... Oorja Protonics .... Open Algae ... Open Monoclonal Technology ..... Open Silicon ... OpenWater Power .... Opertech Bio ..... Opexa Therapeutics ... OpGen ... OPNET Technologies ... Opsonix .... OptTek Systems ... Optelecom ...Optelecom-NKF ... Optherion ... Optical Concepts .. Optigain .. Optimal Technologies ... Optimus Technologies .... OptiNose .... Optivision ... Optofluidics ... OptoLum ..... Optonicus .... Opto Technology ... Optomec .... OPX Biotech ... Oragenics .... OraMerix ... Orasi Medical ... OraSure Technologies .... Orbital Technologies ... Orbotix .... Orchard Therapeutics ..... Orchid Cellmark ... Oregon Iron Works .... Orexigen Therapeutics ... Organic Research .... Organogenesis ... Organovo .. ORIC Pharmaceuticals ..... Oricula Therapeutics .... Origin Medsystems ..... OriginOil ... Orion Energy Systems ... Orion Genomics ... Ormet Circuits ... Orologic... OrphoMed ..... Ortel ... OrthoAccel Technologies ... Ortho Kinematics .... Oryx Technology ...Oscient Pharamceuticals ...Oscilla Power .... Osiris Therapeutics ... OSI Pharmaceuticals ... Oso Biopharmaceuticals Manufacturing .... Osprey Medical .... Ossianix ... OSSIO ..... Ostendo Technologies ... Osteotech ... Osterhout Design Group .... OtoNexus Medical Technologies .... Otonomy .... OtoSense .... Ottomatika .... Outset Medical .... OvaScience ... >Ovid Therapeutics ..... Oxalo Therapeutics .... Oxford Performance Materials ... Oxis International .... Oxygen Biotherapeutics

P3I ... Pace Packaging .... Pacific Biosciences .... Padlock Therapeutics .... Pain Therapeutics ... PaizaBio .... Palvella Therapeutics ... Palantir Technologies .... Palleon Pharmaceuticals .... Palmaz Scientific ..... Palmer Labs ... Paloma Pharmaceuticals ... Panacea Solutions .... Panacos ... Pandion ..... Pandromics ..... Pan Genome Systems .... Panomics ..... PanTheryx .... Paper Battery .... PapGene .... Parabricks .... Paradigm Diagnostics .... Paradigm Sensors ... Paradromics ..... ParaGen Technologies ..... Paragon Bioservices ..... Paragon Dynamics ... Paragonix Technologies .... Parasol Therapeutics ... Paratek Pharmaceuticals .... Parexel International .... Parhelion .... Parion Sciences ... ParkerVision .... Partner Therapeutics ..... Partpic .... Passage Bio ... Passport Systems ... Pasteuria Bioscience ... Pathfinder ... PathoGenetix ... PathoVax ..... Pathway Genomics .... PatientStream ... PatientWise ... Patton Medical Devices ... Patton Surgical .... Pavilion Technologies ... Pax Streamline ... PaxVax ... PDI Therapeutics ..... PDL BioPharma ... PDS Biotechnology ..... Pearl Therapeutics ... Pear Therapeutics ..... PECA Labs .... Pediatric Bioscience .... Peerless Technologies .... Pegasus Sustainability Solutions .... Pelican Products ..... PellePharm .... Pellion Tech ... Peloton Therapeutics ..... Peninsula Pharmaceuticals ..... PennAlt Organics ..... Penumbra ..... PeproMene Bio .... Peptimed ... Peptilogics .... Peptimmune ... Perceptive Navigation ..... Perceptive Sciences ... Perceptron .... PercipEnz Technologies ... Peregrine Semiconductor .... PeriphaGen .... Permeon Biologics ... Perosphere .... Perscitus Biosciences ... Perseon ..... Persimmon Technologies .... PersonalBee ... Personalis ...... Personal Genome Diagnostics .... Pervasis Therapeutics ... Pervasive .... Petra Pharma ..... Pfenex ... Pharmacyclics .... PharmaJet .... PharmAkea Therapeutics .... Pharmasset ... PharmAthene ... PharmatrophiX .... PhaseBio Pharmaceuticals .... Phase Bioscience ... PhaseRx .... Phigenix ..... Phoenix (formerly Phoenix Nuclear Labs) ..... Phoenix Biotechnology .... Phoenix Nuclear Labs ... Phoenix Science .. Phononic Devices ... Photobit ... Photolitec ..... PhotoMedex ... Photonics Innovations ... Photon-X .... PhotoSonix Medical .... PhotoThera ... Photronics ... Phoundry Pharmaceuticals .... Phraxis .... Phrixus Pharmaceuticals ..... Phurnace Software ... PhylloTech ..... Phylonix .... Phylos Bioscience ..... Physcient .... Physical Optics... Physical Sciences ... PhysioGenix ... PhysioSonics ... PhytoTech ... Picolight .... Picometrix ... Piedmont Biofuels .... Pieris Pharmaceuticals ..... Pika Energy ... Pilus Energy .... Pinger ... Pinnacle Technology ... Pioneer Surgical Technology .... Pionyr Immunotherapeutics ..... Pivot Bio ..... Pixelligent .... Pixel Optics .. Pixim ... Pixtronix ... Plakous Therapeutics ..... Planar Energy ... Planar Systems ... Planet Labs .... Plano Microwave ..... Plasan ... PlasmaTech Biopharmaceuticals .... Platelet BioGenesis .... Platypus ... Play-i .... PLC Medical Systems ... Plextronics ... Plexxikon ... Pliant Therapeutics .... Plug Power ... Pluromed ... PLx Pharma ..... PLX Technology .... PMT .... PMV Pharmaceuticals .... PneumRx ..... Point Source .... Polarean ..... Polatis .... Polychromix ... Polyera ... PolyMedica ... PolyMedix ... Polymer Technology Systems ... Polynoma ..... PolyNova .... PolyPlus ... PolyRemedy ... Polysciences ... Polystor ... Portola Pharmaceuticals ... Poseida Therapeutics .... Possis Medical ... Pothole Pros ... PowerGenix ... Powerlight ... Power Precise Solutions ... PowerVision ... Pozen ... PQ Bypass .... Prairie Technologies ..... Pranalytica ... Praxis Biotechnology ..... Precision Biopsy ... Precision BioSciences .... Precision for Medicine .... Precision Genome Engineering .... Precision Ocular Metrology ..... Precision Optics ... Precision Therapeutics (now Helomics) .... Precision Virologics .... Predictive Biosciences ... Pregmama ..... Presage Biosciences ... Presidio Pharmaceuticals .... Pressure BioSciences ... PreTalen ..... Prevail Therapeutics ..... Preventice ..... Prevention Pharmaceuticals .... Prieto Battery ..... Primary Data ..... Primera Biosciences ... Primordial .... Primorigen Biosciences ... Primus Power .... Princeton Satellite Systems ..... Principia Biopharma .... Prism Solar Technologies .... Procept BioRobotics ..... ProCertus BioPharm ... Processa Pharmaceuticals ..... Proclara Biosciences (formerly NeuroPhage Pharmaceuticals) .... Procyrion .... Profectus BioSciences . .. Progenics Pharmaceuticals ... Progenity .... Progeny Systems ..... Prologic ... Promedior ... Promega ..... Promentis .... Pronutria ..... Propagenix ..... Propeller Health .... Propulsive Wing .... ProstaGene .... Protagonist Therapeutics .... Protein Foundry ..... Protein Sciences ... ProteinSimple (formerly Cell Biosciences) .... Proteon Therapeutics ... Proteostasis Therapeutics ... Proteotech ... Proteus Biomedical ... Proteus Digital Health .... Protez Pharmaceuticals .... Prothena .... ProThera Biologics ... Proto Labs ... Proton Energy Systems ...Protonex .. Prototype Productions .Provagen ... Provenance Biopharmaceuticals ... Provention Bio .... Proventys ... Provista Diagnostics .... Pryor Medical Devices ..... PsiKick ..... pSivida ... PTC Therapeutics .... Pulmatrix ... Pulmonx .... Pulmotect ..... Pulse Electronics .... PulseTherapeutics .... Puma Biotechnology ..... PUR Biologics ..... Pure Bioscience .... Purfresh ... Purillume ..... Pursuit Vascular ... PurThread .... PvP Biologics

Qcept Technologies .... Qcue .... QD Vision ... QED ... qFuzion ..... Qioptiq ... QM Power ... Qpex .... QPixel ... QR Pharma ... QSpex .... Qteros ... QuaDPharma .... Quadra-Aerrow International ... Quadraspec ... Quad Technologies .... Qualcomm ... QualityMetric ... Qualtech Systems .... Qualtré ... Quanterix ... QuantRx Biomedical .... Quanttus .... QuantTera .... Quantum Circuits ..... Quantum Epitaxial Designs ... Quantum Fuel Systems... Quantum Logic Devices ... Quantum Materials .... QuantumSphere .... Quantum Xchange .... Quark Biotech ... Quark Pharmaceuticals ... Qubitekk ..... Quentis Therapeutics ..... Quick–Med Technologies .... Quid ..... Quidel ... Quincy Bioscience ... Quintessence Biosciences ... Quorum Systems

Radant Technologies ... Radiabeam Technologies ... Radiance Technologies .... Radiant Photonics...Radiation Monitoring Devices ... RadioMedix ... Radius Health .... Rafagen ... Rainbow Organic Farms ... RainDance Technologies ... RainStorm ... Rain Water Solutions ... Rallybio ..... Raland Therapeutics .... RaNA Therapeutic ... RAN Biotechnologies .... Range Fuels ... Rapamycin Holdings ..... RaPharmaceuticals ... Rapid Diagnostek ... Rapid Micro Biosystems ... Rapiscan ... RareCyte ..... Raser Technologies .... Raydiance ... Raydiant Oximetry .... Raymond .... Raze Therapeutics .... RE2 .... Ready Robotics ..... Reata Pharmaceuticals .... Rebellion Photonics .... Rebion ..... Rebiotix .... Receptor Logic ... Receptos ..... Recodagen ... Recombinetics ... ReconRobotics .. Recovery Engineering ..... Recro Pharma .... Recursion .... Redox Power Systems .... Red Rock Biofuels .... RedShift BioAnalytics .... Redwood Robotics .... RedZone Robotics .... RefleXion Medical .... Refuge Biotechnologies .... Regado Biosciences ... ReGear Life Sciences ..... ReGen Biologics ... Regenerative Medical Solutions ..... Regenerative Sciences ... Regentys (formerly Asana Medical) .... Regenxbio .... Regulus Therapeutics ... Rehabtics .... Relay Therapeutics ..... ReliantHeart .... ReliefBand Technologies ..... Relievant Medsystems ..... Relypsa .... Remedy Plan Therapeutics .... Remedium Technologies ... RemoteReality .... Rempex Pharmaceuticals .... Renaissance Services ..... Renegade Materials .... Reneo Pharmaceuticals ..... Renerva ..... ReNeuroGen .... Renewable Alternatives ... Renewable Energy Group .... Renmatix ..... RenovoDerm ..... Renovia .... Renovion .... Renovis ... Rentech ... Replidyne ... Repligen .. Replimune Group .... Research Frontiers .. Research Innovations ..... Resolve Therapeutics ... Resolvyx Pharmaceuticals ... Resonetics ..... Respicardia ... Respira Therapeutics .... Response Genetics ... Restoration Robotics ..... resTORbio ..... Restore Medical ... Retectix ..... Retek ...Rethink Robotics ... Retia Medical .... Retriever Technology .... RetroSense Therapeutics ..... Reva Medical ... Revance Therapeutics Pharmaceutical .... Revegen ... ReVision Optics .... ReVision Therapeutics .... Revitope Oncology ..... ReVivo Medical .... RevMedx .... ReVolt Tech ... Revolution Medicines .... ReWalk Robotics (Israel) .... Rexahn Pharmaceuticals ... Rex Computing ..... RF Code ... RFMicron .. RFS Pharma ..... RF Surgical. .... Rgenix .... Rhenium Alloys .. Rheos Medicines ..... Rheostat Therapeutics ..... Rheumco .... Rhevision ... Rho ... Rhythm Pharmaceuticals ... Rhythmia Medical ... Ribometrix .... RiboNova .... Ribon Therapeutics ..... Rib-X Pharmaceuticals ... Rice Technology ..... Ridgetop Group ... Rigel Pharmaceuticals .... RightEye ..... RightHand Robotics .... Rinat Pharmaceuticals .... Rinovum Women’s Health ..... Rio Grande Neurosciences ..... RipCode ... Rite Solutions .... Ritter Pharmaceuticals ..... River Vision Development ..... Rive Technology ... RJA Dispersions ... R.L. Phillips ... RMH Sciences ... Robb Surgical Devices .... Robopsy ... Robotic FX ... Robotics VISION Technologies ..... Robotic Technology ... Rocket Pharmaceuticals .... Rockwell Medical ..... Rocky Research .... Rodeo Therapeutics ..... Rodin Therapeutics ... Roka Bioscience ..... RoosterBio .... RootPath .... Rosina Food Products .... Ross Valve ..... Rotational Medical .... RotoMetrics ..... RoverMed Biosciences ..... Rowbot Systems .... Royole ..... RQx Pharmaceuticals .... RRE Solar .... Rubicon Tech ... Rubigo Therapeutics .... Rubitection ..... Rubius Therapeutics .... RubrYc Therapeutics ..... Rules-Based Medicine ... Rushford Hypersonic ... Ruud Lighting ..... RxFunction ... RXi Pharmaceuticals ... RxMedic .... Rypos

S2 ... Sadasis .... SafeShot .... Saffron Technology .... Sage Electrochromics ... SADAR 3D .... Sage Science ... Sage Therapeutics ...Sakti3 ... Salarius Pharmaceuticals ..... Salient Surgical Technologies ... Salix Pharmaceuticals ... Salutaris Medical Devices ..... SAM Medical .... Sancilio Pharmaceuticals .... Sand 9 . .. Sandia Biotech .... Sangamo Biosciences ... Sangart ... Santalis Pharmaceuticals ..... Santarus .... Sanuwave Health .... Sapheon .... Sapphire Energy .... SARbarcode .... Sarda Technologies ... Sarepta Therapeutics .... SatCon Technology ... Satori Pharmaceuticals .... Savara Pharmaceuticals .... Savi ... SBH Sciences ... Scanadu ..... Scholar Rock .... Sciaderm ..... SciClone Pharmaceuticals ... Sciencescape ..... Scientific Conservation .... Scientific Research ... Scientific Solutions ... Scientific Systems ... SciFluor Life Sciences ... Scilex Pharmaceuticals .... Scinovia ..... Scioderm .... SciQuest ... Scopic Software ... Scout Bio .... Scynexis ... SD Catalyst Group ... SDL .. SeaChange ... Seacoast Science ... Seahawk Biosystems ... Seahorse Bioscience ... Seaside Therapeutics .... Seattle BioMed ..... Seattle Genetics ... Seattle Medical Tech .... Sebacia .... Second Genome .... Second Sight Medical Products ... Securboration ..... Secure Computing ... Sedia Biosciences ..... Seeo ....Segetis ... S.E.G-WAY Orthopaedics .... Seldon Labs ... Selecta Biosciences ... SELLAS Life Sciences Group .... SeLux Diagnostics .... Sema4 Natalis ..... Semiconductor Laser ... SemiProbe ... Semler Scientific .... Semma Therapeutics .... Semnur Pharmaceuticals .... Semprius ... Semprus BioSciences .... Sencera International ... SenesTech ..... SenGenix .... Senior Scientific ..... Seno Medical Instruments .... Senomyx ... SensAble Technologies ... Sense .... Sense Diagnostics .... Senseonics ..... Sensintel .... Sensiotec ... Sensors Unlimited ... SensorTran ... Sentelligence ... Senti Biosciences ..... Sentient Technologies ..... SentreHEART ..... Sepracor ... SeprOx .... SeQual Technologies ... Sequella ... Sequel Pharmaceuticals .... Sequenom ... Sequenta ... Sequent Medical .... SeraCare Life Sciences ... Seragon Pharmaceuticals .... Seraxis ..... Seres Therapeutics (formerly Seres Health) .... Serenex ... Sermonix Pharmaceuticals .... Servergy ..... SetPoint Medical .... Seurat Therapeutics ..... Seventh Sense Biosystems ... SGB Biofuels ..... SGX Pharmaceuticals ... Shamrock Energy ... Shape Pharmaceuticals ..... Shape Security .... Shapeways .... Sharklet Technologies ..... Sharp Edge Labs ..... Sherlock Biosciences Shift Labs ..... Shift Pharmaceuticals ..... Shiloh Labs ....Shine Medical Technologies ... Shore Thing Shellfish .... Shuttle Pharmaceuticals ..... Si-Bone .... Sicel Technologies ... SiCortex ... Sideris Pharmaceuticals ..... SI Diamond Technology .... Sienna Biopharmaceuticals ..... Sierra Energy ..... Sierra Monolithics ... Sierra Nevada ... Siga Technologies ... SiGe Semiconductor ... Sigilon Therapeutics .... Sigma Labs (NM) .... Sigma Technologies .... SignalFX (formerly Signal Fuse) ..... Signal Genetics .... Signature Genomic Laboratories ... Sila Nanotechnologies .... Silarus Therapeutics .... Silatronix .. Silent Power ... Silicon Biosystems Menarini ..... SiliconBlue .... Silicon Laboratories ... Silicon Mountain Design .. Silicon Space Technology .... Silk .... SilkTech Biopharmaceuticals ..... Silk Tech .... Siluria ... Silverbrook ... Silverback ..... Silvergate Pharmaceuticals .... Silver Spring Networks ... Simbol Materials ... Simply Incredible Foods ... SiMPore ... Simulation Technology and Applied Research ... Simulution ... Singlera Genomics ..... Singulex ... Sinmat ... SiNode Systems ..... Sintact Medical Systems ..... Sion Power ... SiOnyx ... Sioux Manufacturing ... Sirga Advanced Biopharma .... Sirion Therapeutics ... Sirnaomics ..... Sirna Therapeutics ... Sirtris Pharmaceuticals ... Sisu Global Health ..... Sitari Pharma ..... Skybox Imaging .... Skyhawk Therapeutics ..... Skyline Medical .... Skyonic ... SLI .. SLIPS Technologies ..... SmartCells ... Smart Modular Technologies ... SmartSpark Energy Systems ... Smart Structures .... Smart Wires ..... SmartZyme BioPharma .... Smisson-Cartledge Biomedical ... Smooth-Stone ... SNP Bio ..... Socrates Health Solutions .... Soft Machines .... Soft Robotics ..... SoftSwitching Technologies ... Soft Tissue Regeneration ... Soladigm (now View) ..... SolAero Technologies ..... Solaicx .... Solais Lighting .... Solana Surgical ..... SolaranRx ..... SolarBridge Technologies ... Solar Connection .... Solarea ..... Solaria ... Solarmer Energy ... Solar Power Technologies ... SolarWinds ... Solazyme ... Solexant ... Solexel ... SolFocus ... Soliant ... Solid Biosciences .... Solid Concepts ..... SolidEnergy .... Solidus Biosciences ..... SolidWorks ... Soliris .... Soliton ..... Solixia ... Solix Biofuels ... SolMap Pharmaceuticals ... SoloHealth ... Solomon Technologies ... Solo Power .... Solstice Biologics .... Soluble Therapeutics .... Solx .... Solyndra ... Soma .... SomaLogic .... Somatic Labs ..... Somaxon Pharmaceuticals .... Somerset Therapeutics .... Somna Therapeutics ... Sonalysts ... Soneter .... Sonex Aircraft ... Sonitus Medical ... Sonivate ..... SonoSite ... Sonovex .... Sontra Medical ... Sonus Pharmaceuticals ... Sophiris Bio .... Sophono ..... Soraa .... Sorrento Therapeutics .... Soteira ... Sostena .... Sotera Wireless ... Sound Pharmaceuticals ..... Sourcefire ... Source MDx ... Southwall Technologies ... Southwest Windpower ... Space Dev ... Spaltudaq ... Spansion .... Sparkbuy ..... SparkCharge .... Spark Therapeutics .... Sparo Labs ..... Spatial Photonics ... SPEC ..... Spectra254 .... Spectragenetics .... Spectral Energies ..... Spectral Systems ..... Spectranetics ... SpectraWatt ... Spectro Coating ... SpectrumS4 .... Speech Tails ... Speer Medical .... Spero Therapeutics ..... Spinal Modulation ..... Spinal Restoration ... Spinal Simplicity ..... Spinal Stabilization Technologies ..... SpineEX .... SpineGuard ... Spineology ... Spine Wave .. Spintech .... Spin Transfer Technologies .... SpiralGenetics .... Spiral Therapeutics .... Spiration ... Spire ... Spirox (formerly Nasoform) ..... Spoonflower .... Spotfire ... Spot On Sciences ... Spredfast ... Spring Bank Pharmaceuticals ... SpringLeaf Therapeutics ... SpringWorks .... SpringWorks Therapeutics .... SPR Therapeutics .... Spyrix ....SQZ Biotech ..... SRL ... Staktek Holdings ... Standard Bariatrics .... STAR Cryoelectronics ... Starfire ... Startech Environmental ... Startup Circle Pharma .... StarVision Technologies .... Stasys Medical ..... SteadyMed Therapeutics ..... Stealth BioTherapeutics ..... Stealth Therapeutics ... Steel City Optronics .... Stellaray .... Stellar Biotech .... Stellar Science .... Stellent .... Stemagen ... StemBioSys .... Stem Cell Assurance (Now BioRestorative Therapies) .... StemCells ... Stemcentrx ..... StemCo Biomedical ... Stemgent ... StemImmune .... Stemina Biomarker Discovery ... Stemonix ..... Stem Pharm .... Stereotaxis ... Sterilmed ...... Sterling Semiconductor ..... StimMed ..... Stirling Energy .... Stoke Therapeutics ..... Stottler Henke ... Straight Flight .... Stratagene ... Strata Oncology ..... Stratasys ... Stratatech ... Strategic Response Initiatives .... Stratos Genomics ... Strella Biotechnology ..... Stromedix .... Strongbridge Biopharma ..... Sucampo Pharmaceuticals ..... Summit Technology .... Sun BioPharma ..... Sun Catalytix .... Sunesis Pharmaceuticals .... SunHealth Solutions ... Suniva .... Sunovion Pharmaceuticals ... SunPower ... Sun Power Biodiesel ... Sunrise Ridge Algae ....Sunshine Heart .... Suntech ... Suono ..... Superconductive Components ... Superconductor Technologies ... SuperDimension ... SuperFlex ..... Superior Organoid Technologies ..... Supernus Pharmaceuticals .... SuperPower ... Superprotonic .... SupraSensor ..... Surefire Medical .... Surface Logix ... Surface Oncology ..... Surgient ... SurgiQuest .... Surmet ... SurModics ... Suro Biopharma ..... Suros Surgical Systems ..... Surrozen .... SURVICE Engineering ..... Sustainable Bioproducts .... Sustainable Oils .... SustainX ... Sutro Biopharma ..... Sutron ..... SutroVax ..... SuturePro Technologies (now Ceterix) .... SuviCA .... SuVolta ... Suzlon Rotor ... SVS ... SPEC ... Swallow Solutions .... SweetSpot Diabetes Care ... Swift Biosciences .... Syagen Technology ... Symbiomix Therapeutics ..... Symbiont Web ... Symbotic ... Symetrix .... Symic Biomedical ..... Symyx Technologies ... Synack .... Synageva BioPharma ... SynAm Vaccine .... SynapDx .... Synaptics ... SynCardia Systems ..,.. Synchroneuron .... SynchroPET .... Syndax Pharmaceuticals ... Syndexa Pharmaceuticals .... Synedgen .... Synergy Biomedical .... Synergy Pharma ..... SynGen .... Synlogic ..... Synopsys .... SynSonix .... Synta Pharmaceuticals ... Syntax-Brillian ... SyntheMed ... Synthetic Biologics ..... Synthetic Genomics .... SyntheZyme ..... Synthorx .... Syntimmune ..... Syntrix Biosystems .... Syntronics .... Synvitrobio ..... Syros Pharmaceuticals .... Sysgain .... Syslogic .... Systagenix Wound Management ..... Systems and Processes Engineering SPEC ... Systima Technologies ..... Sytera

T2 Biosystems ... T3D Therapeutics ..... Tabula ... Taconic BioSciences ..... Tactical Engineering and Analysis ..... Tactile Systems Technology .... Tactiva Therapeutics ..... TAI Diagnostics ..... Talaris Therapeutics .... Talecris Biotherapeutics ... Talee Bio ..... Taligen Therapeutics ... Talima Therapeutics ... Tal Medical ... Talon Therapeutics ... Tandem Diabetes Care ... Tangen Biosciences ..... Tango Therapeutics ..... Tanox ..Tantaline .... TapImmune .... Tarari ... .Targacept ... TargeGen ... Targ-Anox ... Targanta ... Targazyme (formerly)America Stem Cell.... Targeson ... Targeted Genetics ... Targeted Growth ... Taris Biomedical .... Tarveda Therapeutics ..... Tascent .... Tauriga Sciences .... Taxa Biotechnologies ..... Taxon Biosciences .... Taxus Cardium (formerly Cardium Therapeutics) ... Taylor Devices ..... TCR² Therapeutics ..... TDA Research .... Tealium ..... TearScience ... TearSolutions .... Tech-X .... Techniscan Medical Systems ... Technology and Devices Int'l ... TechTol Imaging ... TELA Bio ..... Telecardia ... TeleContinuity ... Telefactor ..... Telemedicine Up Close operates as DxUpClose ...... Telik ... Tempest Therapeutics ..... Templex Technology... Tempus ..... Tenax Therapeutics .... Tenaya Therapeutics ..... Tendril ... Tendyne Holdings ..... Tensha Therapeutics ... Tepha ... TeraDiode .... TeraDiscoveries (now Cloud Pharma) .... Terapio ... TeraStor ... Terrabon ... Terrajoule ... TerraMetrics ... Terumo BCT .... Terus Technologies .... TESARO .... TeselaGen Biotechnology .... Tessera Technologies ... Tethys BioScience .... Tetra Discovery Partners .... Tetragenetics ... TetraLogic Pharmaceuticals ... Tetraphase Pharmaceuticals ... TetraVue ... Tezzaron Semiconductor .... TFF Pharmaceuticals .... TGS Knee Innovations ... TG Therapeutics .... Thar Pharma .... Thalchemy ..... The ExOne .... The Medicines ..... Therabron Therapeutics ..... Theraclone Sciences ... Theragenics .... Therametric Technologies ... Theranos .... Therion Biologics ... Thermacore ... Thermage ... Thermal Gradiant .... Thermal Spray Technologies .... ThermalTherapeutic Systems ... Thermedical ... ThermoAura .... ThermoCeramiX .... ThermoGenesis .... Thermon ... TherOx .... Thesan Pharmaceuticals .... Theseus... Thetis Pharmaceuticals ... ThingMagic... Third Wave Technologies .. Thoratech Tech ... Thorley Industries .... ThreeRivers 3D ..... Threshold Pharmaceuticals ... ThromboVision .... Thyritope Biosciences .... Tiax ... Tibbetts Industries ... Tibion ..... Tiburio Therapeutics ..... Tilera ... Tillges Technologies ... Tioma Therapeutics ..... TissueGene ..... TissueLink ... Tissue Regeneration Systems .... Titan Pharmaceuticals .... Titan Spine ..... TJ Technologies .... TLC Precision Wafer ... Tmunity Therapeutics .... Tobira Therapeutics .... Tocagen ... Tokai Pharmaceuticals .... Tolerx .... TomoTherapy ... Tone Tree ..... Topia Technology .... TopicalRemedy .... Topokine Therapeutics .... Torax Medical ... Torque Therapeutics ..... Total Immersion ... TotipotentRx .... Totus Solutions .... TP Therapeutics ..... Trace Genomics ..... Tracon Pharmaceuticals ... TranS1 .... TransAstra .... Transatomic Power .... Transcend Medical ...Transcept Pharmaceuticals .... TransCorp ..... Transcriptic ..... TransEnterix ... Transgenomic ... Translattice ..... TransMedics ... Transmeta ... TransMolecular ... Transphorm ..... TransTech .... TransTech Pharma (now vTv Therapeutics) ... Transzyme Transzyme Pharma ... Traverse Biosciences ... Traycer Diagnostic Systems ..... Trellis Bioscience ... Trellis Earth Products ... Trethera .... Trevena ... Trevi Therapeutics ..... Trex Enterprises ... Triad Semiconductor .... Tri Alpha Energy ..... Triangle BioSystems .... Tribogenics .... Tribologix .... Trice Medical .... Trice Orthopedics .... Tricida ..... Trident Systems ... Trilumina .... Trimble Navigation .... Trimeris ... Triquint Semiconductor ... Triton Systems ... Trius Therapeutics ... TriVascular Technologies .... Trovagene ..... Trubion Pharmaceuticals ... Tru-D SmartUVC ..... True Diagnostics .... True Health Diagnostics .... True North Therapeutics .... Truestone ..... TruTouch Technologies ..... Try Eco ..... Tryton Medical ... Tularik .... Turtle Mountain Communications .... TVA Medical ... Tvardi Therapeutics .... Twelve .... Twentyeight-Seven Therapeutics ...... Twin Star Medical ... Twist Bioscience ..... TwoXAR ..... Tyme Technologies .... TypeZero Technologies .... Tyrosine Pharmaceuticals .... Tyrx

uBiome .... UCAN ... UES ... Ulthera .... UltraCell ... Ultragenyx .... Ultralife Batteries ... Ultramet... Ultradian Diagnostics ..... Ultraviolet Sciences ... Unbounded Robotics .... Unchained Labs .... UNIAX ... Unica ... Unidym ... UniEnergy Technologies ..... Unified Nexsys .... Unilife ..... Uni-Pixel .... Uniqure .... United Devices ... United Therapeutics ... United Therapies ..... Unity Biotechnology .... Universal Cells ...... Universal Display ... Universal Robots ..... Universal Technical Resources .... Universal Technology .... Unleash Immuno Oncolytics ..... Unum Therapeutics .... Unwired Nation ... Uptake Medical ... UQM Technologies ... Urbix Resources .... Urigen Pharmaceuticals .... UroGene Pharma ..... US Nanocorp ... Uroplasty ..... US Bioscience ..... US Silicones ... UTC Power .... Utilidata ... Utron ..... UVision360

Vaccinex ..... Vaccinogen .... Vader Systems ..... VakSea .... Vala Sciences ....Valencell ... Valence Technology .... Validity Sensors ... Valmont Industries .... Vanda Pharmaceuticals ... Vanguard Space Technologies ..... Vapogenix ..... Variant Pharmaceuticals ..... Vascudyne ..... Vascular Biogenics (also VBL Therapeutics) ..... Vascular Designs ... Vascular Genesis ..... Vascular Pathways ... Vascular Pharmaceuticals .... Vascular Solutions ..... Vasculox .... VasoGenix Pharmaceuticals ... Vasoptic Medical ..... Vast Therapeutics .... Vativ Technologies ... Vaxart ... Vaxess Technologies .... VaxGen ... VaxInnate ... vCalc .... Vecna Tech ... Vectorlogics .... Vedanta Biosciences .... Veeva Systems .... Veezyon ... VeinAid ... Velano Vascular .... Velicept Therapeutic ..... Velocimed ... Velomedix ... VelosBio ..... VenatoRx Pharmaceuticals ..... Venaxis ..... Vendormate .... Veniti ... Vensun Pharmaceuticals .... VentiRx ... Ventria Bioscience ... Ventrix ..... Ventrus Biosciences ... Veracode ... Veracyte ... Veran Medical Technologies ..... Verastem ... VeraSun Energy ... VerAvanti .... Verax Biomedical ... Verdezyne ... Vergent Bioscience ..... VerinataHealth ... Verenium ... Vericel (formerly Aastrom Bio) .... Verifica-BG ... Veritas Genetics ..... Vermillion .... Vermont Composites ...Veros Systems ... Verrica Pharmaceuticals .... Versar .... Versartis ... Vestagen Technical Textiles .... Vestaron .... VerteCore ..... VerteraSpine ..... Vertex Pharmaceuticals ... VeruTEK Technologies ... Verve Therapeutic .... Vesper Medical ..... Vextec ... VGBioCogCubed .... V-Glass .... VGo Communications ... VGX Pharmaceuticals ..... ViaCell ... ViaCyte .... Viacor .... Viamet Pharmaceuticals ... ViaSat ... Via Separations .... Vical . .. Vicarious .... Vicus Technologies .... Vidacare ... View ..... Viking Therapeutics .... Vion Pharmaceuticals ... ViraCor Laboratories ... Viracta Therapeutics ..... Viral Genetics .... Virdante Pharmaceuticals ... Virdia .... Virent Energy Systems ... Viresco Energy ... Virobay .... ViroPharma . .. ViroXis ... Virtify . VirtualScopics .... Virtusa ... Viscardia ..... VisEn Medical ... VisiGen Biotechnologies ... VisionGate ..... VisionQuest ..... Vision-Sciences ... Vistagen Therapeutics ... Vistec Lithography ... Visterra ... Visualase .... Vitae Pharmaceuticals ..... VitalMedix ... Vital Therapies ...... Vital Vio .... VitaPath Genetics ... Vitriflex .... Vium ..... Vivex Biomedical .... Vividion Therapeutics ..... Vivisimo .... Vixar ... Vixel ... Vixiar Medical ..... Vizzario .... Vlingo ... VLST ..... VMware ... Voci Technologies .... Volcano .... VoltServer ... VORAGO Technologies (previously Silicon Space Technology) ..... Vorbeck Materials ... Vor BioPharma ..... Vortex Biosciences ..... Vortex Medical ... Voxel .. voxeljet ..... Voyager Therapeutics .... Vtesse .... VT Silicon .... vTv Therapeutics (formerly TransTech Pharma) ..... VUV Analytics .... Vuzix .... Vyriad .... Vyrx Pharmaceuticals ..... VytronUS

WaferGen Biosystems ... Wakonda Technologies ... Walker Magnetics Group ... Waste2Watergy .... Waveband ..... Wave Computing ..... Waveguide ..... WaveRx ... Weinberg Medical Physics .... WellStat Therapeutics .... Whole Biome ..... Whole Trees ..... WiBotic .... Wicab ..... WildcatDiscovery .... Wiliot ..... Willow Garage ... Wilocity .... Wilson Greatbatch .. Wilson Tool International .... Wilson Wolf Manufacturing ... WiMax.com ... Windlift ... Windtree Therapeutics ..... WinSanTor .... Wintegra ... WISErg .... Wizbe Innovations ... WMR Biomedical (now Arsenal Medical) ... Wolf Technical Services ... WoundZoom .... Woven Orthopedic Technologies .... Wright Materials Research ... Wright Therapy Products ..... W Solar Group

X4 Pharmaceuticals ..... Xanofi ... Xanthus Pharmaceuticals ... XBiotech USA ..... X-Body Biosciences ... Xcede Technologies ..... XCELL BIOLOGIX ..... Xcell Biosciences .... Xcellerex ... XChanger Companies .... Xencor .... X-energy ..... Xenetic Biosciences .... Xenex Disinfection Services .... Xenex Healthcare Services ... XenoGen Biosystems .... Xenomics ... Xenoport ... Xeris Pharmaceuticals ... Xetrios Therapeutics .... XF Technologies .... xG Technology .... Xidex ... Xitronix ... XL Hybrids ... Xlumena .... Xoc Pharmaceuticals ..... Xollai ... Xolve (formerly Graphene Solutions) ... Xoma ... XProSciences (now Icagen) ..... X-Ray Optical .... X-Spine .... XSunX ... Xtalic .. Xtant Medical Holdings ..... Xtent ...Xtreme Power ... XTuit Pharmaceuticals .... Xunlight .... XyloCor Therapeutics .... Xynomic Pharma

Yan Engines ... Yardney Technical Products .... Y-Carbon ... Yulex .... Yumanity Therapeutics .... Yurie

Z ... Zacharon Pharmaceuticals .... ZafGen .... Zavante Therapeutics ..... ZBB Energy ... ZeaChem ... ZeaKal .... Zebra Imaging .... Zebra Medical Vision (Israel) ..... Ze-gen ... ZenBio ... Zenomics .... Zenverge ..... Zeo .... Zephyr Technology ... ZeptoMetrix .... ZeroFOX .... Zero Locus .... Zero Mass Water .... ZetaRx Biosciences .... Zeteo Tech .... Zilker Labs ... Zinc Matrix Power ... Zintera ..... Ziopharm Oncology ... Ziptronix .... Zogenix ... Zosano Pharma ... ZPower ... ZS Genetics ..... zSpace ..... ZS Pharma ... ZSX Medical .... Zumobi ... Zunum Aero ..... Zurex Pharma ... Zwitter Technology .... Zyga Technology .... Zygo ... Zymergen ..... ZymoGenetics ... Zynerba Pharmaceuticals .....Zymeworks ..... Zyomyx ... Zystor Therapeutics ... Zyvex Technologies

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