About six months after the FDA approved the first treatment for peanut allergy, a new biotech, IgGenix (South San Francisco, CA) has raised $10 million to discover antibodies that could address that and other common allergies. The six-person startup, is based out of the Johnson & Johnson JLABS incubator [Sarah de Crescenzo, xconomy.com, August 5, 20]
Coronavirus vaccine developer Moderna has confirmed that its vaccine candidate could, in fact, be the most expensive on the market. [Boston Business Journal, Aug 5, 20]
More is better. “If you had asked me this a couple months ago, I would have said we just need to be doing the PCR tests,” said Susan Butler-Wu, a clinical microbiologist at the University of Southern California. “But we are so far gone in this country. It is a catastrophe. It’s kitchen sink time, even if the tests are imperfect.” [Katherine Wu, NY Times, Aug 5, 20] If tests are plentiful and frequent, false negatives will soon be corrected.
Sorrento Thera up 31% [Aug 4, 20]
GentiBio (Boston, MA, Seattle, WA, and Israel; no SBIR) an emerging biotherapeutics company developing engineered regulatory T cells (EngTregs) programmed to treat autoimmune, alloimmune, autoinflammatory, and allergic diseases, announced it has closed a $20 million seed funding [company press release, Aug 4, 20]
Immunic up 28% [Aug 3, 20] a clinical-stage biopharmaceutical company focused on developing best-in-class, oral therapies for the treatment of chronic inflammatory and autoimmune diseases, today announced positive top-line data from its phase 2 EMPhASIS trial of lead asset, IMU-838, the company's selective oral DHODH inhibitor, in patients with relapsing-remitting multiple sclerosis (RRMS). [company presss release, Aug 2, 20] also announced that it intends to offer and sell 5 million shares of its common stock in an underwritten public offering. [company presss release, Aug 3, 20]
Plug Power up 19% [Aug 3, 20]
Athenen Therapeutics (Boston, MA; no SBIR) raised $7M in equity in a $15M funding round, according to an SEC filing. [BostInno, Aug 3, 20]
After five years, $30 million and outside support from a tiger team of tech experts from the U.S. Digital Service, the [SBA]’s online small business verification program, Certify, is ineffective and being scrapped. [Aaron Boyd, govexec.com, Aug 3, 20]
By tying career advancement to the publishing of papers, academia already creates incentives for scientists to do attention-grabbing but irreproducible work. The pandemic strengthened those incentives by prompting a rush of panicked research and promising ambitious scientists global attention. [Ed Yong, The Atlantic, Aug 3, 20]
Fluidigm (South San Francisco, CA; $2.4M SBIR) up 21% [Jul 31, 20] announced execution of a letter contract with the National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering, for a proposed project under the agency's Rapid Acceleration of Diagnostics (RADx) program. The project, with a total proposed budget of up to $37 million, contemplates expanding production capacity and throughput capabilities for COVID-19 testing with Fluidigm(R) microfluidics technology. [company press release, Jul 31, 20]
[NIH] is revealing the first beneficiaries of its Rapid Acceleration of Diagnostics (RADx) program, and Helix (San Mateo, CA; no SBIR) is on the receiving end of $33 million in federal funding as a result. Helix is a health tech startup founded in 2015 that focuses on insights derived from personal genomics, but the company has also developed a COVID-19 test that detects the presence of SARS-CoV-2 using RT-PCR methods. The funding will be used to support Helix’s efforts to scale its COVID-19 testing efforts, with the aim of achieving a rate of 100,000 tests per day by this fall, and then extending the throughput capacity even further after that. [Darrell Etherington, TechCrunch, Jul 31, 20]
Fantasy exposed. Capital investment [since Reagan] remained relatively weak despite deep tax cuts (as it does today under Donald Trump). [Jeff Madrick, reviewing Robert Reich's THE SYSTEM Who Rigged It, How We Fix It, NYTimes, Jul 31, 20]
Capricor Therapeutics down 19% [Jul 30, 20]
Inhibrx (LaJolla, CA; $1.5M SBIR) couldn’t get their $75 million IPO over the goal line last year. But with the fervor for new biotech filings seemingly growing on Wall Street, they plan to see how a $100 million play will work out now. This time around, Inhibrx touts four Phase I drugs in the pipeline developed on its single domain antibody (sdAb) platform, three of which are geared toward various cancers. [Nicole DeFeudis, Endpoints News, Jul 29, 20]
Inovio Pharmaceuticals (labs in San Diego, CA; $1.4M DOD SBIR in 2012), funded by DARPA, entered Phase 1 trials for its DNA-delivered covid-19 vaccine in April, making it the second company to enter trials in the United States. The [Plymouth Meeting] Pennsylvania-based firm, which began trials 80 days after receiving the virus’s genetic code, is looking to begin its Phase 2 and 3 trials this summer, pending regulatory approval. [Pau Sonne, WashPo, Jul 30, 20]
The White House is trying to solve bad polling by agreeing to indefensibly bad debt. This proposal is not targeted to fix precise problems — it’s about Democrats and Trumpers competing to outspend each other. [Sen Ben Sasse, Jul 29, 20]
Alector (South San Francisco CA; $1.5M SBIR) down 24% [Jul 29, 20] a clinical-stage biotechnology company pioneering immuno-neurology, announced preliminary data from its Phase 1b and open-label Phase 2 studies of AL001, for the treatment of people with frontotemporal dementia with a progranulin gene (GRN) mutation (FTD-GRN). AL001 is the company's wholly owned, investigational human monoclonal antibody designed to modulate progranulin, a key regulator of immune activity in the brain. [company press release, Jul 28, 20]
Altis Biosystems (Chapel Hill, NC; $1.2M SBIR) stem-cell technology startup, has raised a $3.1M round .... Altis' stem-cell platform was created at UNC-Chapel Hill following a NIH research award to develop a microfluidic organ-on-a-chip to mimic the human colon. [ATLinno, Jul 29, 20]
Constant Therapeutics (formerly Constant Pharmaceuticals, Boston, MA; no SBIR) announced that peptide drug will be used in a Phase 2 clinical trial in the treatment of Covid-19 patients. [BostInno, Jul 29, 20]
Thrive Earlier Detection (Cambridge, MA; no SBIR) dedicated to extending and saving lives by incorporating earlier cancer detection into routine medical care, announced that it has raised $257 million in a Series B financing. [company press release, Jul 29, 20]
Omega Therapeutics (Cambridge, MA; no SBIR founded 2017) pioneering a new category of genomic medicine through epigenomic programming, announced the completion of an $85 million financing [to] support progression to first-in-human clinicaltrialsofthe company’s Epigenomic Controllersfor programsin oncology, inflammation, autoimmune, metabolic,and rare genetic diseases. [company press release, Jul 29, 20]
POP Biotechnologies (Buffalo, NY; $900K SBIR, founded 2015) a preclinical stage biotech developing next-generation drug and vaccines products, announces that it has entered an agreement to receive a [$3 million] equity investment from South Korean vaccine manufacturer Eubiologics Co., Ltd. in conjunction with the establishment of a joint venture, EUPOP Life Sciences. [company press release, July, 2020]
MediciNova (LaJolla, CA; no SBIR) down 33% [Jul 28, 20]
Success attracts mimics. AstraZeneca is set to pay Daiichi Sankyo $1 billion to co-develop the antibody-drug conjugate (ADC) DS-1062 outside of Japan. The deal, which features a further $5 billion in milestones, represents a big bet on a solid tumor drug that hits the same target as Immunomedics’ approved ADC [Nick Paul Taylor, Fierce Biotech, Jul 27, 20]
MediciNova (LaJolla, CA; no SBIR) up 95% [Jul 27, 20] biopharmaceutical announced an agreement with BioComo (Japan) for joint development of a SARS-CoV-2 vaccine using BC-PIV, a human parainfluenza virus type 2 vector developed by BioComo and Tetsuya Nosaka, M.D., Ph.D., professor of Mie University. MediciNova has been granted exclusive worldwide development rights to use BC-PIV for SARS-CoV-2 vaccine development. BC-PIV, an innovative non-transmissible viral vector is derived from the recombinant human parainfluenza virus type 2 (hPIV2). [company press release, Jul 27, 20]
Capricor Therapeutics up 27% [Jul 27, 20]
Capricor Therapeutics up 29% [Jul 24, 20]
Novavax and FUJIFILM Diosynth Biotechnologies, a world leading contract development and manufacturing organization (CDMO) for biologics, viral vaccines and gene therapies, announced an agreement to manufacture bulk drug substance for NVX-CoV2373, Novavax’ COVID-19 vaccine candidate. FDB’s site in Morrisville, North Carolina has begun production of the first batch of NVX-CoV2373. This arrangement falls under Novavax’ recent $1.6 billion award by the federal government as part of Operation Warp Speed. [joint companies press release, Jul 24, 20]
FLIR Systems announced it has been awarded a full-rate production option worth $21.8 million on an indefinite-delivery/ indefinite-quantity (IDIQ) contract with the United States (U.S.) Army. FLIR will deliver its Agentase™ C2 disclosure spray to detect G- and V-series nerve agents, highly toxic chemical warfare agents. [company press release, Jul 15, 20]
Battery tech startup NanoGraf (Chicago, IL; one $1M SBIR as Sinode) has landed a $1.65 million [DOD] grant to develop longer-lasting batteries to power military equipment. The grant from the DoD is meant to develop silicon anode-based lithium-ion technology that is compatible with all portable batteries. [company press release, Jul 22, 20]
Bra-Ket Science, a stealthy research firm in Austin [TX}, reported raising $1.8M in equity funding out of a $3.1M offering. The company’s sparse website says it’s working on a new approach to creating “practical, room-temperature qubit storage.” [Brent Wistrom, AustinInno, July 1, 20
Savi Technology (Alexandria, VA; early Navy SBIR) has landed a [DOD] contract worth up to $45M to supply its military branches and other government agencies smart technologies and connected devices — portable deployment kits, readers and satellite communications among them, as well as support services for the software and hardware. It follows Savi’s collaboration with the DOD to get its logistics tech to the Army National Guard ($3.2M) and the Army Reserve ($5.1M) amid the coronavirus crisis. [Sara Gilgore, DCInno, Jul 23, 20
Sorrento Therapeutics (San Diego, CA; $4.8M SBIR) and SmartPharm Therapeutics (Cambridge, MA; no SBIR)) announced today the signing of a letter of intent for Sorrento to acquire SmartPharm, a gene-encoded therapeutics company developing non-viral DNA and RNA gene delivery platforms for COVID-19 and rare diseases, with broad potential for application in enhancing antibody-centric therapeutics, including against COVID-19. [joint companies press release, Jul 24. 20]
Lexington Medical (Billerica, MA; no SBIR) a medical device company delivering minimally-invasive surgical stapling solutions, and BOWA Medical (Germany), a leading innovator of energy based surgery products for medical applications, have entered into a commercial agreement the companies announced. [company press release, Jul 22, 20]
Experimental blood test detects cancer up to up to four years before these people walk into the hospital, says Kun Zhang, a bioengineer at the [UCSD], and a co-author of the study. “That’s never been done before.”. The test they developed, called PanSeer, detects methylation patterns in which a chemical group is added to DNA to alter genetic activity. Past studies have shown that abnormal methylation can signal various types of cancer, including pancreatic and colon cancer. [Rachel Nuwer, Scientific American, Jul 22, 20]
Tech Startup Funding Declines [12%] as Pandemic Drags On In the first full quarter spanning the pandemic, [Angus Loten, Wall Street Journal, Jul 23, 20]
Vesigen Therapeutics (Cambridge, MA; no SBIR) is developing technology that could best other [cell or gene therapy] approaches at penetrating the cellular membrane, and it launched with $28.5 million to advance its research. [Frank Vinluan, xconomy.com, Jul 22, 20]
Small businesses are bracing for a prolonged crisis while short on cash and customers. Hopes for a quick economic recovery from the coronavirus pandemic have been dashed, and companies are exhausting rescue funds. Many are shutting down or slashing jobs again, Ruth Simon, Amara Omeokwe and Gwynn Guilford report. [Jeff Sparshott, Wall Street Journal, Jul 23, 20] Do your bit: order-in or dine-in neighborhood eateries' meals.
Applied Optoelectronics up 16% [Jul 21, 20]
Biomerica down 24% [Jul 21, 20]
Olema Oncology (San Francisco, CA; no SBIR) biopharmaceutical company developing innovative targeted therapies for women's cancers, announced the closing of an oversubscribed $54 million Series B financing [to] advance OP-1250, the Company's lead program in breast cancer, into Phase 1/2 clinical development and expand ongoing research and development activities. [company press release, Jul 22. 20]
Tech immigramts needed. Universities are in trouble and the influx of brainpower from overseas is shrinking. The long-term consequences could be disastrous. [Caleb Watney, The Atlantic, govexec.com, Jul 20, 20]
iBio (NYC, NY; no SBIR) up 64% [Jul 20, 20]
INmune up 26% [Jul 20, 20]
Capricor Thera up 18% [Jul 20, 20]
medical device maker CardioFocus (Marlborough, MA; $300K SBIR) raised $12M in equity per an SEC filing. [BostInno, Jul 20,20]
Imvax (Philadelphia, PA; no SBIR), a clinical-stage biotechnology company whose groundbreaking personalized neo-antigen immunotherapy, IGV-001, is being studied in patients with glioblastoma multiforme (GBM), and whose proprietary technology has the potential to advance care for patients with serious, unmet medical needs in other solid tumor cancers, announced the completion of a $112 million Series C financing. [ company press release, Jul 16, 20] total funding $167M [crunchbase.com]
“We designed an economic response that was predicated on a public health response that did not materialize” [Trevon Logan, Ohio State University economist and research associate at the National Bureau of Economic Research, Vox, Jul 17, 20] And the leader who bet solely on the health response has to face the voters who might be shedding their credulity.
Fixation Consequences. Hospitals Are Suddenly Short of Young Doctors — Because of Trump’s Visa Ban [Dara Lind, ProPublica, Jul 17, 20] Feeding and endangering his base, who are not people, just expected votes.
Vaccinex up 40% [Jul 17, 20]
Dynavax Technologies up 20% [Jul 17, 20]
VBI Vaccines up 23% [Jul 17, 20]
PhaseBio Pharmaceuticals up 17% [Jul 17, 20]
Novavax up 17% [Jul 17, 20]
Moderna up 16% [Jul 17, 20]
Adagio Therapeutics (Waltham, MA; no SBIR) launched with the closing of a $50 million Series A financing, to advance its portfolio of coronavirus antibodies as both therapeutics and prophylactics against SARS-CoV-2 as well as future coronavirus outbreaks. [company press release, Jul 16, 20]
Glympse Bio (Cambridge, MA; $2M SBIR) announced an early stage Series B of $46.7M Developer of a diagnostic platform designed to facilitate noninvasive disease monitoring through bio-marker technology. The company's platform utilizes precisely engineered diagnostic agents that interrogate the body for certain disease states and then carry the message to the urine for analysis, enabling physicians to use noninvasive and predictive monitoring of multiple human diseases like certain cancers, blood-clotting diseases and fibrosis of the liver faster and more accurately than currently available bio-marker technologies. [pitchbook.com, Jul 15, 20] total funding $75M [crunchbase.com]
Elicio Therapeutics (Cambridge, MA; no SBIR, founded 2019), developing vaccines and immunotherapies to defeat an array of aggressive cancers, raised $6.1M in equity in a $30M funding round, according to an SEC filing [Rowan Walrath, BostInno, Jul 17, 20]
Dreamworld continues. Measures aimed at slowing the pandemic are facing political resistance. [Talal Ansari and Allison Prang, WSJ, Jul 17, 20] Voters treated as gullible and believing in miracles from political promises. Voters do, however, show considerable cognitive dissonance that politicos exploit.
BioMerica up 18% [Jul 16, 20]
INmune Bio down 18% [Jul 16, 20]
HelixBind (Boxborough, MA; $8M SBIR) developing an innovative diagnostic platform to revolutionize care for invasive infections such as sepsis, announced it has been awarded a new $3MM [NIH] grant [company press release, Jul 16, 20]
Fluidigm up 20% [Jul 15, 20]
Perceptron down 27% [Jul 15, 20]
INmune Bio down 17% [Jul 15, 20] announced that it has commenced an underwritten public offering of shares of common stock.
Vaxart down 15% [Jul 15, 20]
Why govenment welfare. the government learned the extent of malnutrition and other negative side effects of the Depression and the years of drought that created the Dust Bowl. Nearly half the men drafted in the first twelve months were sent home. More than 100,000 were rejected because they could neither read nor write. Another group was toothless or lacked more than half their teeth. [Peter Cozzens, excerpt from The Rise of the GI Army, 1940-41 by Paul Dixon, Wall Street Journal, Jul 16, 20]
INmune Bio (La Jolla, CA; no SBIR) up 78% [Jul 14, 20] a clinical-stage immunology company focused on developing treatments that harness a patient's innate immune system to fight disease, today reported clinical data demonstrating that its lead drug candidate, XPro1595, decreases neuroinflammation in patients with Alzheimer's disease. [company press release, Jul 13, 20]
Perceptron (Plymouth, MI; one SBIR in 1987) up 112% [Jul 14, 20] a leading global provider of 3D automated in-line measurement solutions and coordinate measuring machines, announced that a global, Tier-1 automotive supplier has selected Perceptron's in-line measurement technology to measure the battery frame, compartment, and lid for an upcoming new electric vehicle launch. [company press release, Jul 13, 20]
Vaxart up 40% [Jul 14, 20]
Cytokinetics up 16% [Jul 14, 20]
Equillium (La Jolla, CA; no SBIR) down 47% [Jul 14, 20] announced that as reported by its partner, Biocon Limited, a clinical trial conducted in India by Biocon demonstrated that itolizumab significantly reduced mortality in patients hospitalized with COVID-19. Biocon has announced that the Drugs Controller General of India (DCGI), the regulatory agency that oversees drug approvals, has granted restricted emergency use of itolizumab for the treatment of cytokine release syndrome (CRS) in COVID-19 patients with moderate to severe acute respiratory distress syndrome (ARDS) in India. [company press release, Jul 13, 20]
Government goes suspiciously private. Hospitals have been ordered to bypass the Centers for Disease Control and Prevention and send all patient information to a central database in Washington, raising questions about transparency. [Sheryl Gay Stolberg, NYTimes, Jul 14, 20] Imagine that, a spur of the moment non-competitive contract for a dramatic shift in flow of public information during a presidential campaign. Politically inspired? Perish the thought.
Another problem is that the administration no longer has many experts [about stimulus] the president could lean on for advice if he was willing to do so. [Jonathan Bernstein, Bloomberg, Jul 13, 20] When loyalty and the readiness to answer YES are the prime qualifiers for high level federal service. Does a 33-year old [brings deep connections to Donald Trump and controversial Silicon Valley venture capitalist Peter Thiel] head of DOD R&D sound like a responsible appointment?
Vaxart (South San Francisco, CA; $3.5M SBIR) up 52% [Jul 13, 20] announced that it has raised gross proceeds of approximately $90 million through its At-the-Market (ATM) facility [company press release, Jul 13, 20]
Vaccinex up 18% [Jul 13, 20]
Moderna up 15% [Jul 13, 20]
NextCure down 54% ,{jul 13, 20] Based on the current enrollment criteria and clinical response data, at this time the company does not plan to advance the non-small cell lung cancer (NSCLC) and ovarian cancer cohorts into the stage 2 portion of the Simon 2-stage trial. [company press release, Jul 13, 20]
Oragenics (Tampa, FL, $900K SBIR) following a further review of new data and other factors related to the Company’s international multicenter Phase 2 clinical trial of AG013 in oral mucositis, Oragenics has determined to cease further development of AG013 in this indication by discontinuing the trial and withdrawing the applicable Investigational New Drug application [company press relese, Jul 10, 20]
Precision BioSciences (Durham, NC; $500K SBIR), a clinical stage biotechnology company dedicated to improving life with its novel and proprietary ARCUS® genome editing platform, announced that the Company will regain full rights and all data it generated for the in vivo chronic hepatitis B virus (HBV) program developed under its 2018 collaboration agreement with Gilead Sciences. ... Gilead funded the research and development and was responsible for the clinical development and commercialization of potential therapies. [company press release, Jul 10, 20]
Why [ejecting foreign high tech students] could backfire: The US just doesn’t have the irresistible pull it once did, and other countries are competing hard to attract them. America’s leading companies and universities are tough to match, but Canada, China, the United Kingdom, Australia, and others now boast flourishing tech hubs, world-class research institutions, and bold public policies to support R&D. [Tina Huang and Zachary Arnold, researchers with Georgetown University’s Center for Security and Emerging Technology, Jul 13, 20] Trump's apparent approach is to loudly eject the immigrants easiest to find. His economic rationale is basically a myth that all immigrants displace American workers. Both counter-evidence and American popular opinion say otherwise.
The first drug for neurofibromatosis type 1 (NF1) is available to patients following the FDA’s approval of the AstraZeneca treatment earlier this year. Biotech startup NFlection Therapeutics (Wayne, PA; $300K SBIR) is vying to be runner-up, but its founders say they can eventually win out with a drug that takes a different approach than the commercialized pill while also offering a safer and more effective way of addressing the tumors and skin bumps caused by the rare disease. NFlection is developing its drug as a topical gel. [Frnk Vinluan, xconomy.com, Jul 9, 20]
Aura Biosciences (Cambridge, MA; no SBIR) developing a new class of therapies to target and selectively destroy tumor cells, raised $10M in equity in a $17M funding round, according to an SEC filing. [Srividya Kalyanaraman, BostInno, Jul 10, 20]
It ain't over 'til it's over.[Yogi Berra, 1973] People are rebelling against isolation, and against science and public health. They want the old, pre-Covid-19 world, back, but it cannot be had. The virus doesn’t feel frustration or react to it. It’s not aware of your children or your job or your vacation plans. It’s not aware of our politics. The virus is a virus, mindless, and in this case, incredibly efficient and effective. It will pass from person to person for as long as that is possible. The political debate over mask wearing is a human concern, one that works to the virus’s benefit. [Charles Blow, NY Times, Jul 13, 20] A personal view: a year's self-shelter at home is a lot better than an order to the war zone in SE Asia. Evem for an avid traveler.
Perfect is the enemy of good. In the past week, “the single biggest relief package in American history,” as President Trump accurately labeled the legislation, has evolved toward the political fate of most other spending bills. Candidates who benefited from it, however indirectly, are accused of taking handouts. [David Weigel, WashPo, Jul 12, 20]
Tranquis Therapeutics (San Mateo, CA; no SBIR) launched with $30 million in Series A funding committed to the discoveryand development of innovative medicines with the potential to revolutionizethe management of neurodegenerative and aging-related diseases [conpany press release, Jul 9, 20]
Kymera Therapeutics announced [it has entered into a multi-program strategic collaboration with Sanofi (NASDQ: SNY) to develop and commercialize first-in-class protein degrader therapies targeting IRAK4 in patients with immune-inflammatory diseases. The companies will also partner on a second earlier stage program. Kymera will receive $150 million in cash upfront and may receive more than $2 billion in potential development, regulatory and sales milestones, as well as significant royalty payments. Kymera retains the option to participate in US development and commercialization for both programs. [Kymera press release, Jul 9, 20]
Fluidigm up 28% [Jul 8, 20]
Nanovircides up 26% [Jul 8, 20] announced that excellent safety and tolerability of the drug candidates it is developing against SARS-CoV-2 to treat COVID-19 spectrum of diseases was observed in an animal model. The nanoviricides drug candidates tested in this safety/tolerability study have previously shown strong effectiveness against lung infection by a SARS-CoV-2 like coronavirus, namely, hCoV-NL63, in an animal study as previously reported by the Company. [company press release, Jul 8, 20]
Crystal IS (Cohoes, NY; several SBIRs in infant years) is seeking applications for its newly launched UV Accelerator. Experienced startups and small organizations can receive up to $250K for new ideas regarding the use and application of the company’s UVC LEDs for the disinfection of air or surfaces. Learn more and apply here. [BostInno, Jul 8, 20] Now an Asahi Kasei company, is a U.S.-based manufacturer of high-performance LEDs that emit UV light. These LEDs are integrated into our customers’ products to sterilize and disinfect water, air and surfaces in a variety of applications. Additionally, our LEDs can be used as light sources for scientific and industrial instrumentation applications. founded in 1997 by Rensselaer Polytechnic Institute (RPI) professors, Leo Schowalter and Glen Slack to develop native aluminum nitride (AlN) substrate technology for more powerful and reliable semiconductor devices. [company website]
Elementary Robotics (Los Angeles, CA; no SBIR, founded 2017) announced a $12.7M Series A funding round .... has built a hardware and software platform for applying machine learning and computer vision for intelligent automation of quality and traceability workflows in manufacturing and logistics. .... is working with a number of world class manufacturing and logistics companies [company press release, Jul 8, 20]
Carbon Engineering and Aerion have teamed up to test whether synthetic fuels derived from captured CO2 can enable carbon-neutral flights. [James Temple, MIT Tech Rvw, July 8, 20] A thermodynamicist would note that getting useful energy from carbon dioxide requires splitting the molecule which requires as much energy as was released when the molecule was formed.
Disengaged executive. President Trump picked a public fight with federal disease experts while lobbying governors to reopen schools for in-person instruction this fall, and Vice President Pence repeated the president’s threat that federal funds are on the line if state and local officials do not bring students of all ages back to classrooms despite COVID-19 worries. [The Hill, Jul 8, 20] An engaged president would have formed the objective, appointed a temporary czar, developed a workable plan with agreed and legal tasks for the various agencies, coordinated with Congress, and rolled out the workable plan with a national address. Not Trump's style of flashy Executive Orders with little consideration of workability or legality. Just another autocrat appealing to a poltical base.
Corvus Pharmaceuticals (Burlingame, CA; no SBIR) up 81% [Jul 7, 20], a clinical-stage biopharmaceutical company, announced that it has initiated a Phase 1 study to investigate a novel immunotherapy approach for patients with COVID-19. [company press release, Jul 7, 20]
Annovis Bio up 77% [Jul 7, 20]
Hepion Pharmaceuticals (Edison, NJ; no SBIR) up 43% [Jul 7, 20], a biopharmaceutical company focusing on the development of therapeutic drugs for the treatment of liver disease arising from non-alcoholic steatohepatitis ("NASH"), announced that its clinical phase, anti-fibrotic drug candidate, CRV431, additionally was efficacious in two distinct preclinical research models related to COVID-19 disease. [company press release, Jul 7, 20]
Vaxart (South San Francisco, CA; $3.5M SBIR) up 38% [Jul 7, 20] has soared over 2,000% YTD amid an acceptance to the Russell 3000, joining Operation Warp Speed, and the possibility of an effective COVID-19 'tablet' vaccine. [Seeking Alpha, Jul 7, 20]
Novavax up 32% [Jul 7, 20]
Vor Biopharma (Cambridge, MA; no SBIR, founded 2016), an oncology company pioneering engineered hematopoietic stem cells (eHSCs) for the treatment of cancer, today announced it has raised $110 million in a Series B financing [to] advance the company’s lead candidate VOR33 into clinical trials, deepen its portfolio, and accelerate the validation of additional targets for its scientific platform, which is designed to remove redundant proteins so that transplanted stem cells become invisible to targeted therapies while leaving diseased cells vulnerable. [company press release, Jul 7, 20] prior funding $42M [crunchbase.com]
The same week Annexon Biosciences (South San Francisco, CA; no SBIR) announced it had raised $100 million in private financing to advance its research of antibody drugs to treat neurodegeneration, the company filed paperwork with regulators indicating its intention to [IPO]. [Sarah de Crescenzo, xconomy.com, Jul 6, 20]
AlloVir (formerly VeraCyte, Cambridge, MA; no SBIR) is seeking $100M IPO for its T-cell work, which includes an early-stage attempt at a T-cell therapy against the SARS-CoV-02 outbreak partnered with the Baylor College of Medicine. [Ben Adams, Fierce Biotech, Jul 7, 20]
It’s unlikely a coincidence that countries run by women have done far better controlling corona than countries run by men. They’re less obsessed with being “right” and more focused on taking care of things (and people). [KC Cole, Wired, Jul 7, 20]
Liminal BioSciences down 18% [Jul 6, 20]
Novavax (Gaithersburg,MD; $250K SBIR in 2009) announced that it has been selected to participate in Operation Warp Speed (OWS), a U.S. government program that aims to begin delivering millions of doses of a safe, effective vaccine for COVID-19 in 2021. ... awarded $1.6 billion by the federal government to complete late-stage clinical development, including a pivotal Phase 3 clinical trial; establish large-scale manufacturing; and deliver 100 million doses of NVX‑CoV2373, Novavax’ COVID-19 vaccine candidate, as early as late 2020. NVX‑CoV2373 consists of a stable, prefusion protein made using its proprietary nanoparticle technology and includes Novavax’ proprietary Matrix‑M™ adjuvant. [company press release, Jul 6, 20] total funding $777M [crunchbase.com]
Inozyme (Boston, MA; no SBIR) developing novel therapeutics for the treatment of diseases of abnormal mineralization impacting the vasculature, soft tissue and skeleton ... filed for an $86M IPO [Renaissance Capital, Jul 2, 20] total funding $150M [crunchbase.com]
At the current rate of spread—40,000 confirmed cases a day (and maybe five to 10 times that in reality)—it’s only two years until most people in the US have been infected. It means we’re pointed toward what, since the outset, has been seen as the worst-case scenario: a couple of hundred million infected and a quarter-million deaths. If you want to calculate your own death risk, you can do so at covid19survivalcalculator.com. [Antonio Regalado, MIT Tech Review, July 5, 20] The trade-off altternative is to restrict exposure by masking and forbidding dangerous public activity. How will you wager your life against your precious liberty to engage in perilous activity? Would your answer differ if only you would suffer by catching the disease?
Bolt Biotherapeutics (Redwood City, CA; no SBIR, founded 2015), a clinical-stagebiotechnology company developing its Immune-Stimulating Antibody Conjugate (ISAC) platform technology to harness the power of theinnateimmune system to treat cancer, announced the closingof an oversubscribed $93.5 million Series C financing. ... has raised more than $170 million since its founding [company press release, Jul 1, 20]
Ultragenyx Pharmaceutical (Novato, CA; no SBIR), a biopharmaceutical company focused on the development and commercialization of novel products for rare and ultra-rare diseases, announced that the U.S. Food and Drug Administration (FDA) has approved Dojolvi™ (triheptanoin) as a source of calories and fatty acids for the treatment of pediatric and adult patients with molecularly confirmed long-chain fatty acid oxidation disorders (LC-FAOD). LC-FAOD are a group of rare, lifelong and life-threatening genetic disorders in which the body is unable to convert long-chain fatty acids into energy. [company press release, Jun 30, 20]
Alexion Pharmaceuticals (Boston, MA) announced the successful completion of its acquisition of Portola Pharmaceuticals [which] adds Factor Xa inhibitor reversal agent Andexxa® [coagulation factor Xa (recombinant), inactivated-zhzo], marketed as Ondexxya® in Europe, to Alexion’s commercial portfolio. [company press release, Jul 2, 20]
Gateway Biotechnology (St Louis, MO, $1.7M SBIR) biotech startup snags $2.2M [Nathan Rubbelke, St Louis Business Journal, Jul 6, 20]
Aptinyx up 19% [Jul 1, 20]
Inovio Pharma down 27% [Jul 1, 20]
Annexon Biosciences (South San Francisco, CA; no SBIR, founded 2014) [raised] $100 million to move its two clinical-stage programs along and to continue advancing its preclinical pipeline. [Sarah de Crescenzo, xconomy.com, Jul 1, 20]
Amylyx Pharmaceuticals (Cambridge, MA; no SBIR) focused on developing new treatments for amyotrophic lateral sclerosis (ALS), Alzheimer’s disease and other neurodegenerative diseases, announced it has closed an oversubscribed $30 million Series B financing. [company press release, Jul 1, 20]
T2 Biosystems (Lexington, MA; no SBIR) has a rapid coronavirus diagnostic test: the T2SARS-CoV-2 Panel, which provides sample-to-answer results in less than two hours. It is being commercially distributed after validation and meeting requirements for an Emergency Use Authorization request to the FDA. [BostInno, Jun 30, 20]
The U.S. government plans to lend $700 million in coronavirus stimulus funds to trucking firm YRC Worldwide, in exchange for a 29.6% equity stake in the company, the Treasury Department said. [Wall Street Journal, Jul 1, 20] Trump might love the profit possibilities, since he berated "my generals" for not using military operations to collect money for the US Treasury.
Plug Power up 17% [Jun 29, 20]
Cleveland BioLabs down 42% [Jun 29, 20]
startup Cryosa (Roseville, MN; no SBIR) just wrapped up its Series A-2 financing round, raising $8.25 million. [to] develop therapies for obstructive sleep apnea, a condition that affects approximately 22 million people in the U.S. [Burl Gilyard, Twin Cities Business, June 25, 20]
Pandion Therapeutics (Watertown, MA; no SBIR) biotech developing engineered T cells for autoimmune diseases, filed to raise $75M in an IPO. [Rowan Walrath, BostInno, Jun 29. 20] totall funding $135M [crunchbase.com]
When loyalty matters most. FEMA warned states not to use COVID-19 testing supplies it bought under a $10.2 million contract after a ProPublica investigation last week showed the vendor was providing contaminated and unusable mini soda bottles. FEMA signed its first deal with Fillakit on May 7, just six days after the company was formed by an ex-telemarketer repeatedly accused of fraudulent practices over the past two decades. [Ryan Gabrielson and J. David McSwane, ProPublica, govexec.com, Jun 29, 20] Trump has systematically appointed loyalists as government agency heads, and removed inspectors general who found too many faults.
Akouos (Brookline, MA; $200K SBIR) up 29% [Jun 26, 20] a precision genetic medicine company dedicated to developing gene therapies with the potential to restore, improve, and preserve high-acuity physiologic hearing for people worldwide who live with disabling hearing loss, announced the pricing of its [IPO] to raise $212.5 million [company press release, Jun 25, 20]
Translate Bio down 21% [Jun 26, 20]
Vielo Bio down 20% [Jun 26, 20]
Immumic down 15% [Jun 26, 20]
Artiva Biotherapeutics (San Diego, CA; no SBIR for the stealthy), an oncology company focused on developing and commercializing allogeneic natural killer (NK) cell therapies, announced today the launch of the company with the close of a $78 million Series A financing [to] develop off-the-shelf universal NK cells for use in combination with monoclonal antibody therapy and tumor targeting CAR-NK cell therapies. [companyp press release, Jun 26, 20]
Somatus (McLean, VA; no SBIR, founded 2016), a market leader in value-based kidney care, announced it has completed a Series C funding round of $64 million ... brings the Company’s total capital raised to over $105 million [company press release, Jun 23, 20]
self-driving cars have proven to be a technology that—unlike social media—doesn’t particularly favor disruptive startups. The immense capital costs and deadening development cycles are perfect for large companies who can wait out the lean times. [Bloomberg Technology, Jun 29, 20]
Too much tech. Michigan has introduced a bill designed to prevent employers from forcing their staff to accept microchip implants. [Charlie Osborne, ZDNet, June 29, 20]
Toward a dumber government. Trump signed an executive order to overhaul requirements federal agencies use when evaluating job candidates, seeking to downplay the importance of college degrees. The order requires agencies to increase the use of skill assessments and interviews with subject matter experts to determine an applicant's qualifications, rather than simply looking at educational achievements. [Eric Katz, govexec.com, Jun 27, 20] Congress may step in to control anti-intellectual Executive Order land. It's also possible that Trump doesn't know the realties of federal hiring and is only just showing off for his uneducated base.
President Trump signed an executive order that calls on the U.S. government to prosecute individuals who damage statues or monuments and to limit federal support to states and law-enforcement agencies that don’t protect them. [WSJ, Jun 26, 20] Such an order will run into the same wall his sanctuary city edict did: if the law establishing the handout to a jurisdicion did not include such a criterion, an Executive Order to do so is illegal. The showtime President cannot unilaterally change a law.
Voter supression alive and well. The Supreme Court rejected an emergency appeal that sought permission for voters in Texas to cast absentee ballots in this year’s elections if they feared coronavirus risks from voting in person. [WSJ, Jun 26, 20] Elections have consequences.
as my sweet southern Grandmother would say, "Bless their hearts, they're just special stupid. " [David Spencer, Bluffton, SC on NYT piece on MI gov Witmer, commenting on SC Repubs, NYT June 25, 20]
Trump’s Napalm Politics? They Began With Newt. Gingrich wrote the playbook for it all. The nastiness, the contempt for norms, the transformation of political opponents into enemies. [Jennifer Senior, New York Times, June 28, 20]
Nanoviricides up 20% [Jun 25, 20]
Replimune up 18% [Jun 25, 20]
Relay Therapeutics (Cambridge, MA; no SBIR) focused on solid tumors, filed for a $200M IPO. [Rowan Walrath, BostInno, Jun 25, 20] total funding $520M [crunchbase.com]
startup MarvelBiome [Woburn, MA; SBIR) raised $2.3M in equity, according to an SEC filing. [Rowan Walrath, BostInno, Jun 25, 20] with a vision of harnessing the power of microbes for treating various human diseases. We are focused on isolating, identifying, and characterizing microbial populations for novel therapeutic applications. [company website]
Gilead Sciences has agreed to pay $275 million for 49.9 percent of Pionyr Immunotherapeutics (South San Francisco, CA; no SBIR) plus the option to pay another $315 million and make the startup eligible for up to $1.15 billion more in milestone payments to acquire the remaining 50.1 percent. ... developing antibody drugs that take a new approach toward boosting the body’s anti-tumor efforts. [Sarah de Crescenzo, xconomy.com, Jun 23, 20]
Century Therapeutics announced its acquisition of Empirica Therapeutics to leverage its iPSC-derived allogeneic cell therapies against glioblastoma (GBM). [Century press release, Jun 23, 20]
Simcha Therapeutics (New Haven, CT; no SBIR) developing biologic drugs that modulate cytokine pathways, launched with $25m in Series A financing.... lead program involves a customized variant of interleukin-18 (IL-18), a cytokine with potent antitumor effects. [finsmes.com, Jun 25, 20]
Karyopharm Therapeutics announced that [FDA] has approved oral XPOVIO® (selinexor), the Company’s first-in-class, Selective Inhibitor of Nuclear Export (SINE) compound, for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL), not otherwise specified, including DLBCL arising from follicular lymphoma, after at least two lines of systemic therapy. [copany press release, Jun 22, 20]
Since 2005, the One North Carolina Small Business Program has made 423 SBIR/STTR matching awards worth nearly $26 million to more than 250 businesses throughout the state. [SSTI, Jun 24, 20]
With the wealthiest 10% owning 84% of all stocks, and with the bottom 75% owning none at all, a rising stock market does absolutely nothing for the wealth of two-thirds of Americans. [Nouriel Roubini, Project Syndicate, Jun 24, 20]
Loyalty first. The White House is intensifying an effort to hire Pentagon personnel with an undisputed allegiance to President Trump at a moment when his relationship with Defense Secretary has become strained, current and former officials said. [Missy Ryan, Paul Sonne, and Josh Dawsey, WashPost, June 25, 20] Probably will not affect SBIR unless shutdown threatens at new fiscal year start Oct 1. When funding is short, SBIR gets low priority.
Five Prime Thera up 18% [Jun 24, 20]
Shattuck Labs (Research Triangle Park, NC, and Austin, TX; no SBIR), a clinical-stage biotechnology company advancing its proprietary Agonist Redirected Checkpoint (ARC™) platform to develop a novel class of biologic medicines for the treatment of cancer and autoimmune disease, announced the closing of a $118 million Series B equity financing. [company press release, Jun 24, 20] total funding $175M [crunchbase.com]
Already, an estimated 100,000 small companies have shut permanently. [Caroline Mimbs Nyce, The Atlantic, Jun 23, 20]
Tom McTague [The Atlantic], who spoke to more than a dozen European officials and policy experts, writes: “As citizens of the world the United States created, we are accustomed to listening to those who loathe America, admire America, and fear America (sometimes all at the same time). But feeling pity for America? That one is new, even if the schadenfreude is painfully myopic.”
President Donald Trump came to office promising to build a wall around to America to keep foreigners out. He may leave it with foreigners building walls to keep Americans out. [Bloomberg, Jun 24, 20]
Flexible minions. a familiar pattern: President Donald Trump says something that doesn’t line up with the facts held by scientists and other experts at government agencies. Then, instead of pushing back, federal officials scramble to reconcile the fiction with their own public statements. [ProPublica, govexec.com, Jun 23, 20]
Translate Bio up 47% [Jun 23, 20] Sanofi Pasteur (France) and Translate Bio (Lexingon, MA; no SBIR), a clinical-stage messenger RNA (mRNA) therapeutics company, have agreed to expand their existing 2018 collaboration and license agreement to develop mRNA vaccines for infectious diseases. Translate Bio will receive a total upfront payment of $425 million, ... Translate Bio will also be eligible for potential future milestones and other payments up to $1.9 billion, including $450 million of milestones under the 2018 agreement. Of these potential milestones and other payments, approximately $360 million are anticipated over the next several years, inclusive of COVID-19 vaccine development milestones. [joint companies press release, Jun 23, 20]
Inovio Pharma up 41% [Jun 23, 20] announced it has received $71 million funding from the U.S. DOD] to support the large-scale manufacture of the company's proprietary CELLECTRA(R) 3PSP smart device and the procurement of CELLECTRA(R) 2000 devices, which are used to deliver INO-4800 directly into the skin. [company press release, Jun 23, 20]
Cyclerion Thera (Cambridge, MA; no SBIR) up 37% [Jun 23, 20]
AsclepiX Therapeutics (Baltimore, MD; $3.5M SBIR), biopharmaceutical company that uses computational biology to identify potent peptide regulators of vascular homeostasis for the treatment of retinal and other important diseases, announced that it has closed a $35 million Series A financing [which] will fund Phase 1/2a clinical trials of AXT107, the Company’s lead investigational drug, for the treatment of diabetic macular edema (DME), wet age-related macular degeneration (wet AMD) and macular edema secondary to retinal vein occlusion (RVO). [company press release, Jun 24, 20]
Engrail Therapeutics (San Diego, CA; no SBIR) announced the close of a $32 million Series A financing round [to] support the clinical development of its first pipeline asset, ENX-101, a sub-type selective GABA A modulator. [company press release, Jun 18, 20]
Glyscend Therapeutics (Baltimore, MD; no SBIR), developing novel treatments for type 2 diabetes (T2D) and related metabolic conditions, announced the closing of a $20.5 million Series A financing round [to] to support the development of the company’s novel oral polymer therapy for patients with T2D and other metabolic diseases. [company press release, Jun 11, 20]
Sure, Trump threatens China constantly, but he mainly follows through with trade wars that are the equivalent of punching himself in the face out of spite. [Bloomberg, Jun 23, 20]
Five Prime Therapeutics up 45% [Jun 22, 20]
Biomerica up 21% [Jun 22, 20]
Sarepta Therapeutics, the leader in precision genetic medicine for rare diseases, and Codiak BioSciences (Cambridge, MA; no SBIR), a company at the forefront of advancing engineered exosomes as a new class of biologic medicines, announced a global research and option agreement to design and develop engineered exosome therapeutics to deliver gene therapy, gene editing and RNA technologies for neuromuscular diseases. The engineered exosome approach offers the potential to effectively deliver genetic therapeutics without triggering the adaptive immune response. The two-year agreement includes up to five neuromuscular targets. Codiak is eligible to receive up to $72.5 million in upfront and near-term license payments plus research funding. Sarepta is granted an option to any of the candidates developed pursuant to the research alliance. [company press release, Jun 22, 20]
It’s not just that the USA has the highest number of coronavirus cases and deaths in the world. Republican political dysfunction has made a coherent campaign to fight the pandemic impossible. ... we’re seeing a combination of the blustering contempt for science that marks the conservative approach to climate change and the high tolerance for carnage that makes American gun culture unique. No matter how bad things get in red America, it’s hard to imagine where the political will to contain the virus will come from. [Michelle Goldberg, NY Times, Jun 22, 20
Feeling important and in control? The deeper challenge for us humans on Earth — Earth being only one of 40-some billion other Earthlike planets in our galaxy — is that our brains can’t figure out what to do with numbers. “The equation of luck and skill is, at its heart, probabilistic,” Konnikova writes. [Michael Paterniti reviewing THE BIGGEST BLUFF How I Learned to Pay Attention, Master Myself, and Win By Maria Konnikova, NY Times, Jun 23, 20]
Repare Therapeutics (Cambridge, MA and Canada; no SBIR) up 54% [Jun 19, 20], a leading precision oncology company enabled by our proprietary synthetic lethality approach to the discovery and development of novel therapeutics, announced the pricing of its upsized [IPO] to raise $220.0 million. [company press release, Jun 18, 20]
Celldex Thera up 29% [Jun 19, 20] announced the closing of its underwritten public offering to raise $150 million [company press release, Jun 18, 20]
Diamedica Thera up 22% [Jun 19, 20]
Anaptys Bio up 16% [Jun 19, 20]
Neurocrine Biosciences and Takeda Pharmaceutical announced a strategic collaboration to develop and commercialize compounds in Takeda’s early-to-mid-stage psychiatry pipeline. Specifically, Takeda granted an exclusive license to Neurocrine Biosciences for seven pipeline programs, including three clinical stage assets for schizophrenia, treatment-resistant depression and anhedonia. ... Takeda will receive a total of $120 million USD in upfront cash. Additionally, Takeda will be entitled to development milestones of up to $495 million USD, commercial milestones of up to $1.4 billion USD and up to double-digit royalties on net sales. [joint press release, Jun 16, 20]
Assembly Biosciences (South San Francisco, CA; no SBIR), a clinical-stage biotechnology company developing innovative therapeutics targeting hepatitis B virus (HBV) and diseases associated with the microbiome, announced that the Company will regain worldwide rights to all microbiome gastrointestinal programs licensed under its collaboration agreement with AbbVie (formerly Allergan pre-acquisition). AbbVie has decided to terminate the research, development, collaboration and license agreement. This decision was not based on any efficacy, safety, or other data related to the collaboration programs. ... As of March 31, 2020, Assembly had cash, cash equivalents and investments totaling $249 million. [company press release, Jun 18, 20]
Epizyme (Cambridge, MA; no SBIR) a fully integrated, commercial-stage biopharmaceutical company developing novel epigenetic therapies, today announced that the [FDA] has approved the supplemental New Drug Application (sNDA) for TAZVERIK™ (tazemetostat) for two distinct follicular lymphoma (FL) indications. [company press release, Jun 18, 20]
Ultragenyx Pharmaceutical (Novato, CA; no SBIR), a biopharmaceutical focused on the development and commercialization of novel products for rare and ultra-rare diseases, and Kyowa Kirin (Japan), a global specialty pharmaceutical company creating innovative medical solutions using the latest biotechnology, today announced that the [FDA] has approved Crysvita® (burosumab) for the treatment of fibroblast growth factor 23 (FGF23)-related hypophosphatemia in tumor-induced osteomalacia (TIO) associated with phosphaturic mesenchymal tumors that cannot be curatively resected or localized in adults and pediatric patients 2 years of age and older. Crysvita is a human antibody that blocks excess activity of FGF23, a hormone that causes phosphate urinary excretion and suppresses active vitamin D production by the kidney. [company press release, Jun 18, 20]
Alpine Immune Sciences (Seattle, WA; no SBIR), a leading clinical-stage immunotherapy company focused on developing innovative treatments for cancer and autoimmune/inflammatory diseases, and AbbVie, a research-based global biopharmaceutical company, announced an exclusive worldwide option and license agreement for ALPN-101, a first-in-class dual CD28/ICOS costimulation antagonist. ... Alpine will receive an upfront payment of $60 million, and will also be eligible to receive up to an aggregate of $805 million for exercise of the option and success-based development, regulatory and commercial milestones. In addition, Alpine is eligible to receive tiered royalties on net sales of ALPN-101 [joint press release, Jun 18, 20]
Leidos's Dynetics (many SBIRs near the Huntsville AL flagpole) subsidiary has secured a potential 10-year, $356M contract to produce and maintain a suite of foreign radar simulators for use by the U.S. Air Force and the Department of Defense in enterprise-wide test efforts [Mary-Louise Hoffman, govconwire.com, Jun 22, 20]
Markets are the answer; what's the question? The problem with letting private investment alone drive innovation is that the money is skewed toward the most lucrative markets. The biggest practical uses of AI have been to optimize things like web search, ad targeting, speech and face recognition, and retail sales. ... the government has to take on a leading role in directing innovation to meet the public’s most pressing needs. That doesn’t sound like the government the US has now. [David Rotman, MIT Tech Review, July 2020] Free-market government's role is to invest for public benefit where there is no market, only a need.
Innovation. Matt Ridley tells us at the start of his new treatise on the subject, “is the most important fact about the modern world, but one of the least well understood.” Even as it functions as a powerful engine of prosperity — the accelerant of human progress — innovation remains the “great puzzle” that baffles technologists, economists and social scientists alike. [Jon Gertner reviewing Ridley's How Innovation Works: And Why It Flourishes in Freedom, WashPost, Jun 18, 20]
Sailors cheer, Navy brass jeer. In a reversal, the service’s top officer says further investigation revealed lapses in Capt. Brett Crozier’s judgment and actions aboard his COVID-stricken [aircraft carrier] ship. [Bradley Peniston, DefOne, Jun 22, 20]
Tribalism. [Nebraska] Republican Gov. Pete Ricketts has threatened to withhold funds from any county that requires people to wear a mask in public buildings. The Republican governor is forbidding counties to require residents to do something that will, at very minimal personal inconvenience, reduce the spread of covid-19 to their fellow Nebraskans.[Megan McArdle, WashPo, Jun 18,20] Like so many issues rooted in science and medicine, the pandemic is now fully entangled with ideological tribalism. [Lori Rozsa et al, WashPo, Jun 18, 20]
Guarded privacy, unguarded health. N.Y.C. Hired 3,000 Workers for Contact Tracing. It’s Not Going Well. workers have not had much success in getting information from people who test positive. [Sharon Otterman, NY Times, June 21, 2020]
Alpine Immune Sciences (Seattle, WA; no SBIR) up 135% [Jun 18, 20], a leading clinical-stage immunotherapy company focused on developing innovative treatments for cancer and autoimmune/inflammatory diseases, and AbbVie announced an exclusive worldwide option and license agreement for ALPN-101, a first-in-class dual CD28/ICOS costimulation antagonist. [joint press release, Jun 18, 20]
Anavex Life Sciences up 21% [Jun 18, 20]
CryoLife down 25% [Jun 18, 20]
IDEAYA Biosciences down 23% [Jun 18, 20]
Who's paying for MAGA? Critics of the administration’s actions on China say hawkish officials have overreached or adopted misguided measures — for example, pushing a trade war that has resulted in mainly American companies paying about $55 billion in tariffs and caused suffering among farmers, or starting tit-for-tat punishments against Chinese media organizations that have resulted in the expulsions of American reporters from China. [Edward Wong and Michael Crowley, NY Times, Jun 18, 20]
When you wish upon a star... Trump claims the coronavirus pandemic is ending. Data and the experts disagree. [Philip Bump, WashPo, Jun 18, 20] Do presidents have ex officio superior understanding?
IDEAYA Biosciences up 45% [Jun 17, 20]
Diamedica Thera up 19%[Jun 17, 20]
RAPT Thera up 16%[Jun 17, 20]
Chembio Diagnosticsdown 61% [Jun 17, 20] announced that [FDA] has revoked the Emergency Use Authorization granted to the company in April to sell its rapid test for the antibodies domestically. [James T. Madore and Ken Schachter, newsday.com, Jun 17, 20]
Immunic up 17%[Jun 17, 20]
Orca Bio (Menlo Park, CA; no SBIR) is coming out of stealth with a $192 million series D round that will propel a pipeline of “high precision” allogeneic cell therapies and the manufacturing technology behind those treatments. Founded in 2016, Orca Bio zeroed in on manufacturing to make bone marrow transplants safer and more effective. ... brings Orca’s total raised to nearly $300 million [Amirah Al Idrus, Fierce Biotech, Jun 17, 20]
Lassen Therapeutics (San Diego, CA; SBIR) announced it has emerged from stealth and secured $31 million in Series A financing to develop antibodies as potential treatments for fibrosis, rare diseases and oncology. [company press release, Jun 17, 20]
IDEAYA Biosciences up 43% [Jun 16, 20] IDEAYA Biosciences and GlaxoSmithKline plc (British)) announce a strategic partnership in Synthetic Lethality, an emerging field in Oncology. ... IDEAYA will lead the MAT2A program through early clinical development. IDEAYA is responsible for all costs of the MAT2A program prior to the GSK option exercise. Thereafter, IDEAYA is responsible for 20% of global development costs. IDEAYA will receive a 50% US profit share and ex-US royalties for the MAT2A and Werner Helicase programs and is responsible for 20% of global development costs for licensed products being developed with GSK. IDEAYA will receive global royalties for the Pol Theta program, and GSK will cover all research, development, and commercialization costs. [joint companies pres release, Jun 16, 20] Also, IDEAYA announced that it intends to offer and sell up to $60 million of shares of its common stock in an underwritten public offering [company press release, Jun 16, 20]
Annovis Bio up 26% [Jun 16, 20]
Vaxcyte up 15% [Jun 16, 20]
Federal Reserve Chairman Jerome Powell said the economy faces potentially significant long-term damage from higher unemployment and a wave of small business failures due to the coronavirus pandemic despite recent signs of an economic rebound. [WSJ, Jun 17, 20] Beware breezy economic claims by campaigning politicians because lying is an epidemic disease in politics.
Celldex Therapeutics up 37% [Jun 15, 20] announced the [$130M] pricing of its previously announced underwritten public offering. [company press release, Jun 15, 20]
Arcturus Therapeutics up 17% [Jun 15, 20]
Viela Bio (Gaithersburg, MD; no SBIR) announced that [FDA] has approved UPLIZNATM (inebilizumab-cdon) for the treatment of adult patients with neuromyelitis optica spectrum disorder (NMOSD) who are anti-AQP4 antibody positive as a twice-a-year maintenance regimen following initial doses. Approximately 80% of all patients with NMOSD test positive for anti-AQP4 antibodies. [company press release, Jun 11, 20]
BioIQ (Atlanta, GA; no SBIR) a healthcare engagement and clinical adherence technology platform company, announced today availability of the first home test for COVID-19 that combines COVID-19, Flu A / Flu B, and a 21 Test Respiratory Panel from a single saliva sample. Partnering with P23 Labs, one of the first laboratories to receive Emergency Use Authorization (EUA) from the [FDA] for home saliva collection for COVID-19, the availability of this home test signifies a major step forward in the next phase to combat COVID-19. [company press release, Jun 15, 20]
The truth is that government efforts to inform the public about the pandemic have been a colossal failure, which means that most people are hearing mixed and muffled messages about what to do. [Jonathan Bernstein, Bloomberg Opinion, Jun 15, 20] When messages on health depend on politics, disease gets an unfair advantage.
Vaxcyte (formerly Sutrovax, Foster City, CA; no SBIR, founded 2013) up 63% [Jun 12, 20] a next-generation vaccine company seeking to improve global health by developing superior and novel vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide, announced the [IPO] pricing of $250.0 million [company press release, Jun 11, 20] prior funding $177M [crunchbase.com]
Avidity Biosciences (San Diego, CA; $200K SBIR) up 58% [Jun 12, 20] announced pricing of its [IPO] to raise $259M [company press release, Jun 11, 20]
Illumina received an emergency authorization from the FDA for its COVID-19 test designed to sequence the full genome of the novel coronavirus. [Conor Hale, Fierce Biotech, Jun 10, 20]
Lycia Therapeutics is launching out of Versant Ventures with $50 million to develop drugs targeting protein degradation in a new way. ... Enter Lycia’s lysosomal-targeting chimeras, LYTACs. Based on the work of Carolyn Bertozzi, Ph.D., a professor of chemistry and an investigator at the Howard Hughes Medical Institute at Stanford University, LYTACs are designed to “grab” proteins from cell membranes, or proteins that are in circulation, and “drag” them into the cell, where they are degraded by the lysosome. [Amirah Al Idrus, Fierce Biotech, Jun 9, 2020]
Cash is us. Facebook confirmed that it was also developing a venture capital fund to invest in promising start-ups. Other technology giants are engaging in similar behavior. Apple has bought at least four companies this year and released a new iPhone. Microsoft has purchased three cloud computing businesses. ... tech’s largest companies — still wildly profitable and flush with billions of dollars from years of corporate dominance — are deliberately laying the groundwork for a future where they will be bigger and more powerful than ever. [Mike Isaac, New York Times, Jun 13, 20] The monopoly building of the late 19C has re-emerged with a politically neutered federal government. If you want a government in thrall to large biz profit interests, vote for Trump re-election.
Public Education. In times of crisis, a government’s duty is to lead the public through a process of diagnosing the problem and identifying a shared plan for solving it. This is fundamentally an act of public education. ... When the pandemic hit, none of this happened. Trump, the person with the greatest power to educate the public and motivate the whole country behind a common purpose, declined to use that power. [Danielle Allen Foreign Affairs, J/A2020]
Celldex Therapeutics (Hampton NJ; $500K SBIR) up 82% [Jun 11, 20]
Myriad Gdnetics down 21% [Jun 11, 20]
Verve Therapeutics (Cambridge, MA; no SBIR, founded 2018) a next-generation cardiovascular company developing therapies that safely edit the adult human genome to permanently reduce a person’s risk of coronary heart disease, today announced it has raised $63 million in a Series A2 financing [to] use the genetic mutation and the gene editing technology CRISPR to turn off eight genes linked to high cholesterol. [company press release, Jun 11, 20]
Fulcrum Therapeutics (Cambridge, MA; no SBIR, founded 2016) announced the closing of a $68.5 million private placement pursuant to a securities purchase agreement [to] to fund research and development expenses, including the ongoing clinical development of losmapimod for facioscapulohumeral muscular dystrophy (FSHD), the initiation of clinical development of losmapimod for COVID-19 pending review of the Company’s recently filed investigational new drug application by [FDA], the advancement of its hemoglobinopathies program into clinical development and the advancement of both its discovery efforts and product engine capabilities. [company press release, Jun 11, 20] prior funding $140M [crunchbase.com]
The Senate Armed Services Committee voted 25-2 to approve annual authorization of Defense Department spending that exceeds levels requested by the administration in a number of areas, including emerging technology investments to keep pace with China, according to a summary the committee released today. [Mariam Baksh, nextgov.com, Jun 11, 20] Note: authorization s only permisssion, not demand, for appropriation - the money creating step. But these are welcoming days for deficit spending in trillions.
Only large companies with deep pockets will be able to ride out the storm, with the technology giants gaining most of all, as digital interactions become ever more important. A lingering epidemic combined with deep job losses, a prolonged recession, and an unprecedented debt burden will inevitably create tensions that turn into a political backlash—but against whom is as yet unclear. [Francis Fukuyama, Foreign Affars, J/A2020]
National Science Board (NSB) recently released its Vision 2030 report. It identifies the primary challenges facing the S&E enterprise in the United States, the essential elements of leadership, and a roadmap for implementing these recommendations and maintaining U.S. leadership in S&E for the next decade. [SSTI, Jun 10, 20]
China has embarked on a new trillion-dollar push to develop next-generation technologies such as artificial intelligence, data centers, mobile communications, in an effort to catapult the communist nation ahead of the U.S. in critical areas. [Liza Lin, Wall Street Journal, Jun 12, 20]
Trump announces rallies in states where new infections are surging. [The Hill, Jun 11, 20] Maybe he will thank the throng by shaking all their hands whle wearing a hazmat suit.
Arcadia Biosciences, a leader in science-based approaches to enhancing the quality and nutritional value of crops and food ingredients, announced it has entered into a binding term sheet with Industrial Seed Innovations (ISI), an Oregon-based industrial hemp breeding and seed company, to acquire its commercial and genetic assets, including its seed varieties, germplasm library and intellectual property. [company press release, Jun 10, 20]
Verve Therapeutics (Cambridge, MA; no SBIR, founded 2019), a next-generation cardiovascular company developing therapies that safely edit the adult human genome to permanently reduce a person’s risk of coronary heart disease, announced it has raised $63 million in a Series A2 financing [to] advance its lead program through IND-enabling studies and fuel follow-on pipeline programs. ... has raised a total of $123M [company press release, Jun 11, 20]
Two decades to cold nationalism. It is difficult now to remember how high American prestige was less than two decades ago, as recently as Sept. 10, 2001—that post-Cold War unipolar moment when the Yale University historian Paul Kennedy observed that the lone superpower had surpassed even ancient Rome in economic and military dominance—and how quickly that went off course. In what was possibly the worst strategic misdirection in U.S. history, Bush and his neoconservative abettors (who are all in hiding now, conceptually speaking) turned what should have been a globally unifying struggle against the international community’s remaining criminal holdouts, Islamist terrorists, into an exhausting imperialist game of invasion and whack-a-mole, exposing in the process America’s worst vulnerabilities on the ground and in the air. [Michael Hirsh, reviewing The Inevitability of Tragedy: Henry Kissinger and His World, by Barry Gewen, Foreign Policy, Jun 7, 20] You have to return to Lyndon Johnson's 1968 abdication for the start with Nixon-Kissinger of the long decline and recent nationalist abandonment of American hegemony.
Calyxt up 25% [Jun 9, 20]
Biomerica up 19% [Jun 9, 20]
ArcherDX (Boulder, CO; no SBIR) files IPO for up to $100 million [Jensen Werley, Denver Business Journal, Jun 9, 20] offers a robust platform for detecting variants associated with cancers and inherited diseases. [company website]
Histosonics (Plymouth,MN and Ann Arbor, MI; no SBIR), a medical technology company creating a non-invasive device that destroys cancerous tissue, has closed on $40 million in an oversubscribed Series C round [Maddy Kennedy, MinneInno, Jun 9, 20]
Akouos [Brookline, MA; $200K SBIR) is developing a gene therapy to address [hearing loss caused by genetic defects and it’s planning an IPO [for $100M] to finance the first tests of its approach in humans. [Frank Vinluan, xconomy.com, Jun 9, 20]
Dan Levangie [CEO of CereVasc (Boston, MA; no SBIR) CEO]'s medical device startup aims to treat hydrocephalus with a less invasive method that leverages newer technologies now in use for vascular and neurological procedures. As the company prepares to test its device in humans, it is announcing the close of $43.9 million in Series A financing [Frank Vinluan, xconomy.com, Jun 9, 20]
there is a war being waged on our institutions by the president. This war - foreign and domestic - has been a wild success. And these developments leave us weakened and at the mercy of ever-increasing centralized control in the hands of Donald Trump, a particular danger considering he lacks the knowledge and respect for these institutions to see their value and necessity. ... Trump has been the perfect vessel for [Steve] Bannon's vision to tear apart global infrastructure, take power and solidify control. [Jessica Tarlov, The Hill, Jun 9, 20]
the president who now fancies himself an expert on polling began the day by sharing a poll number that is by now pretty obviously made up. ... how his approval rating among Republicans is 96 percent, without ever citing a poll that includes that figure. [Philip Bump, WashPo, Jun 8, 20]
Intravacc (Netherlands), one of the leading translational research and development vaccine institutes with an extensive track record in developing viral and bacterial vaccines and Versatope (Lowell, MA; $1.1M SBIR) developing vaccines and therapeutics, announced that they have signed a research service agreement to further develop a universal vaccine against influenza based on Intravacc's innovative Outer Membrane Vesicles (OMV) technology. Both parties will collaborate to further advance the candidate vaccine through clinical development. signed a research service agreement to further develop a universal vaccine against influenza. Intravacc will provide its services to Versatope in bringing their universal influenza vaccine candidate, VT-105, towards their first clinical trials. [joint press release, Jun 8, 20]
Melinta Therapeutics has struck a deal to buy Tetraphase Pharmaceuticals (no SBIR). The deal, which follows a bidding war with AcelRx Pharmaceuticals (no SBIR), gives Melinta another approved product and potentially complementary R&D expertise to support its bid to bounce back from bankruptcy. [Nick Paul Taylor, Fierce Biotech, Jun 5, 20]
Chinook Therapeutics (Canada) is set to merge with fallen Big Pharma darling Aduro Biotech (Berkeley, CA; $700K SBIR) to create a kidney disease player with $180 million in cash. [Nick Paul Taylor, Fierce Biotech, Jun 3, 2020]
Yes, a chemical. No, there were not chemical irritants. Pepper spray is not a chemical irritant. It's not chemical[said USAG Barr]. [NPR, Jun 8, 20] Au contraire PepperBall’s website declares: “With multiple payload options and a proprietary chemical irritant that’s proven more effective from even greater distances, PepperBall® projectiles offer the protection and versatility for any situation.” (The company did not respond to a request for comment.) What’s that ingredient? It’s called pelargonic acid vanillylamide, or PAVA, a “synthetic'' form of capsaicin, the active ingredient in hot peppers. [Glenn Kessler, WashPo fact checker, Jun 8, 20]
Mr Podsnap was well to do, and stood very high in Mr Podsnap’s opinion. He never could make out why everybody was not quite satisfied, and he felt conscious that he set a brilliant social example in being particularly well satisfied with most things, and, above all other things, with himself. [Charles Dickens, Our Mutual Friend] But not being a natural born American, Podsnap was not eligible to compete with his mirror image, Mr Trump, in this century.
Annovis Bio up 18% [Jun 5, 20]
Liqudia Tech down 16% [Jun 5, 20]
We've been there.“There’s a lot of denial here, as there was in the 1930s,” said Eric Rauchway, a historian at the University of California, Davis, who has written extensively about the Great Depression. “At the beginning of the Depression, nobody wanted to admit that it was a crisis. The actions the government took were not adequate to the scope of the problem, yet they were very quick to say there had been a turnaround.” the evidence is everywhere if you look closely. [Neil Irwin, NY Times, Jun 6, 20] Politicians are positive when holding office, and negative when seeking office.
Kezar Life Sciences (South San Francisco, CA; no SBIR) up 73% [Jun 4, 20] announced updated results from the Phase 1b (Ph1b) portion of MISSION, which is evaluating the safety and tolerability of KZR-616 in patients with systemic lupus erythematosus (SLE) with and without nephritis. [company press release, Jun 3, 20]
Plug Power up 20% [Jun 4, 20]
Replimune up 16% [Jun 4, 20]
Novavax announced that the company has been awarded a contract by the [DoD] for the manufacturing of NVX‑CoV2373, Novavax’ COVID-19 vaccine candidate. NVX‑CoV2373 consists of a stable, prefusion protein antigen made using its proprietary the Defense Health Program, has agreed to fund up to $60 million to support Novavax in its production of several components of the vaccine that will be manufactured in the U.S. The agreement includes a 2020 delivery of 10 million doses of NVX‑CoV2373 for DoD that could be used in Phase 2/3 clinical trials or under an Emergency Use Authorization (EUA) if approved by the U.S. FDA. [company press release, Jun 3, 20] and the company inked a deal with Bothell, Washington-based AGC Biologics to manufacture an element of its Covid-19 vaccine candidate. And it tapped PolyPetide Group to also assist with production. [DCInno, Jun 4, 20]
NASA is calling all entrepreneurs through its newly-launched pilot Entrepreneurs Challenge to seek fresh ideas from new participants to bolster the agency’s science and space exploration goals with new tools and technologies, at lower costs. NASA’s Science Mission Directorate, based in Washington, D.C., is seeking novel ideas from technologists and entrepreneurs in areas including machine learning, artificial intelligence, autonomy, robotics and advanced sensors. White paper submissions are due Friday, June 26, with the challenge event to be held July 29. [DCInno, Jun 4, 20]
a survey from the Society for Human Resource Management (SHRM) found that 52 percent of small businesses expected to be out of business within six months. [SSTI, Jun 3, 20]
The Small Business Administration (SBA) recently rolled out a new website for the SBIR/STTR program which SBA administers. Reorganized and including new landing pages for entrepreneurs, support organizations, and federal agencies, the new page provides quicker and easier access to the right information. [SSTI, Jun 3, 20]
of the nine people of Chinese ethnicity who have been awarded Nobel Prizes in the sciences, eight were U.S. citizens or subsequently became U.S. citizens. [LEE HSIEN LOONG Singapore PM, Foreign Affairs, Jun 4, 20]
The 51-foot ladders. People are sawing through and climbing over Trump’s border wall. [Nick Miroff, WashPo, Jun 4, 20] As predicted by then AZ Gov Janet Napolitano, 50-foot wall? I'll show you a 51-foot ladder.
Translate Bio down 19% [Jun 3, 20]
PROMISS Diagnostics (Milwaukee, WI; no SBIR, founded 2017), developing an early-detection ovarian cancer test, has raised $400,000 in a seed round of funding, the company announced. PROMISS Diagnostics is a venture-stage biotech company that develops bio-analytical solutions to assist physicians in improving women’s health outcomes. [Milwaukee BizTimes, Apr 29, 20]
“No powerful political actor had set out to destroy the American political system itself — until, that is, Trump won the Republican nomination,” [Massa] Gessen writes. “He was probably the first major party nominee who ran not for president but for autocrat.” [Jennifer Szalai reviewing Surviving Autocracy, NY Times, Jun 3, 20]
Nanoscope Technologies (Bedford, TX; $2.6M prior SBIR, founded 2009) announced receiving a $2 million multi-year [NIH SBIR] to advance its therapeutic gene and delivery platform. “Through laser delivery, we have now overcome the limitation on size of the therapeutic genes that can be delivered”, said Subrata Batabyal, co-investigator of the grant. [Kevin Cummings, North Texas Inno, Jun 1, 20]
Dynavax Tech up 29% [Jun 1, 20]
Novavax up 15% [Jun 1, 20]
Arca biopharma down 27% [Jun 1, 20]
Codiak BioSciences ( Cambridge, MA; no SBIR) at the forefront of advancing engineered exosomes as a new class of biologic medicines, announced that it has entered into two strategic collaborations with the Ragon Institute of MGH, MIT and Harvard to investigate the potential of its exoVACC vaccine platform in (1) SARS-CoV-2, the virus that causes COVID-19, and in (2) human immunodeficiency virus (HIV). [company press release, Jun 1, 20] total funding $168M [crunchbase.com]
Personal Genome Diagnostics (Baltimore, MD; $1M SBIR) looks to raise $3.5M following FDA clearance for cancer diagnostics tech [Morgan Eichensehr, Baltimore Business Journal, May 27, 20]
No happy early morning in America. The U.S. economy could take the better part of a decade to fully recover from the coronavirus pandemic and related shutdowns. [Congressional Budget Office, Jun 1, 20]
Trump doing his thing. The belief in Beijing, Moscow and Berlin is that the U.S. can no longer lead the globe. ... For its part, the Chinese leadership seems to believe that it is impossible to conciliate Mr. Trump, but that there is also little to fear from him. ... They likely believe that the triple threat of the pandemic, economic crash and civil unrest in the U.S. will promote an American withdrawal from global issues no matter who wins in November. [Walter Russell Mead, Wall Street Journal, Jun 2, 20] Trump's America First now means America no longer first as walls, tariffs, and withdrawals do their work of estranging America.
Dynavax Tech up 26% [May 29, 20]
Minerva Neurosciences down 72% [May 29, 20] announced that the Phase 3 trial of roluperidone to treat negative symptoms in schizophrenia did not meet its primary (reduction in PANSS Marder Negative Symptoms Factor Score or NSFS) and key secondary (improvement in the Personal and Social Performance Scale Total Score or PSP) endpoints. [company press release, May 29, 20]
Macrogenics down 16% [May 29, 20]
VentureOhio announced that it plans to cease operations. The organization worked to attract venture capital for early-stage companies to Ohio. VentureOhio directors decided to wind down after losing its leader earlier this year and because the pandemic put its biggest event of the year, an awards dinner that usually attracts around 600 people, in jeopardy. Leaders say that their advocacy work will continue through other programs throughout the state,
Q. I don’t remember being taught much of anything about [the 1918 Spnish flu] in school. Why are we not more familiar with how devastating it was? A. Well, until a couple of decades ago, historians wrote only about what people did to people. It was very unusual for historians to write about what nature did to people. [Joe Heim interviewing John M. Barry, the author of The Great Influenza: The Story of the Deadliest Pandemic in History, WashPo, May 30, 20] If people and their polticians ignore or make up history, we will repeat epidemics about every decade. And with little appreciation of history and mathematics, the country will be putty in the hands of unscrupulous politicians.
Science doubted. A housing crisis is imminent. Many parts of the country are reopening prematurely. Protesters have stormed state capitals, demanding that businesses reopen. The country is starkly dividing between those who believe in science and those who don’t. [Roxane Gay, NY Times, May 30, 20] Politics creates a lot of experts with expertise that extends only to getting elected.
ARCA biopharma (Westminster, CO; no SIR) up 386% [May 28, 20] announced a new development program to evaluate AB201 (rNAPc2), a potent, selective inhibitor of tissue factor (TF), as a potential treatment for COVID-19 associated coagulopathy (CAC) and the related inflammatory response. CAC is one of the most serious adverse effects seen in COVID-19 patients. AB201 has previously undergone clinical testing through Phase 2 in more than 700 patients for other indications, generating substantial safety data, which the Company believes may enable more rapid development. [company press release, May 28, 30]
Phasebio Pharma up 36% [May 28, 20] receives clearance of IND application from U.S. FDA under Coronavirus Treatment Acceleration Program (CTAP) "VANGARD" trial will assess the efficacy and safety of PB1046 in hospitalized COVID-19 patients at high risk for rapid clinical deterioration and acute respiratory distress syndrome Based on FDA feedback, PhaseBio believes that positive, clearly interpretable and clinically meaningful trial results may enable PhaseBio to submit a Biologics License Application [company press release, May 27, 30]
Five Prime Therapeutics down 16% [May 28, 20]
IDEAYA Biosciences up 23% [May 28, 20]
Novavax developing next-generation vaccines for serious infectious diseases, announced the acquisition of Praha Vaccines 9(Czech Republic) [for $167M] cash .... includes a biologics manufacturing facility and associated assets in Czech Republic. The facility is expected to provide an annual capacity of over 1 billion doses of antigen starting in 2021 for NVX‑CoV2373, Novavax’ COVID-19 vaccine candidate [compamy press release, May 27, 20]
Six months after banking a $100 million venture round, Avidity Biosciences (La Jolla, CA; $200K SBIR) is heading to the public market. The company filed to raise up to $100 million in its IPO, which will push its lead muscle disorder program through IND-enabling studies and into the clinic in 2021. [Amirah Al Idrus, Fierce Biotech, May 26, 20]
Wake-up coming. Subsidies will soon end. Americans will then feel the economic pain—and revolt. Historically, American elections after a crisis have been decided on the question of who can more competently lead the country to better days. Yet unlike previous challenges, the true nature of America’s economic crisis hasn’t set in on the American people. When it does, the familiar political fault lines fused with millions unemployed could make 2020 the most explosive ideological election in modern history. [Josh Holmes, Wall Street Journal, May 29, 20]
Mersana Thera (Cambridge, MA; no SBIR) up 69% [May 27, 20] a clinical-stage biopharmaceutical company focused on discovering and developing a pipeline of antibody-drug conjugates (ADCs) targeting cancers in areas of high unmet medical need, today reported interim safety, tolerability and efficacy data from the ongoing expansion portion of the Phase 1 study evaluating XMT-1536, its first-in-class ADC candidate targeting NaPi2b, in patients with ovarian cancer and non-small cell lung (NSCLC) adenocarcinoma. [company press release, May 27, 20]
Arcturus Thera down 29% [May 27, 20]
Q32 Bio (Cambridge, MA; no SBIR) developing biologics to restore healthy immune regulation, announced the company's pipeline and plans to enter the clinic this year with its lead candidate. Enabled by a $46M Series A financing [is] advancing a portfolio of biologics targeting the body's innate and adaptive immune systems. The company has a robust product pipeline including a monoclonal antibody antagonist of the interleukin-7 receptor (IL-7R), and a complement therapeutics platform that has generated fusion proteins that downregulate complement activity specifically in disease-affected tissues. [company press release, May 27, 20]
RE2 Robotics (Pittsburgh, PA; no SBIR), a developer of human-like robotic manipulation systems, has received $2.5 million in funding from the Office of Naval Research to continue the development and commercialization of its technology under the Dexterous Maritime Manipulation System (DM2S) program. [David Edwards, Robotics & Automation, May 27 20]
Virna Therapeutics (Boston, MA: no SBIR) announces that they are partnering with University of Toronto to in-license neutralizing antibodies, to treat COVID-19. The discovery was made in the laboratory of Sachdev Sidhu, PhD., a professor of Molecular Genetics at the University of Toronto ... Virna Therapeutics has a three-pronged strategy to target the COVID-19 virus: (1) neutralizing antibodies that will prevent the virus from entering host cells, (2) CRISPR/Cas13d-based and LNA-based technologies for the treatment and prevention of RNA virus infection and (3) novel protease inhibitors that will prevent replication and release from host cells. [company press release, May 27, 20]
Investors have just pumped $27.5 million into Nanotech Energy (Los Angeles, CA; no SBIR) Because the company claims its graphene based lithium batteries can charge 18 times faster than conventional lithium-ion batteries. [Steve Hanley, Cleantechnica, May 25, 20]
A group of bipartisan lawmakers introduced legislation to boost research into emerging technology including artificial intelligence and quantum computing. The Endless Frontiers Act would create a Directorate of Technology at the National Science Foundation (NSF), and would rename the NSF the National Science and Technology Foundation. The new directorate would be given $100 billion over five years to invest in American science and technology research, with specific research areas including cybersecurity, robotics, AI, quantum computing, national disaster prevention and biotechnologies. In addition, the Department of Commerce would be given $10 billion over five years to establish “regional technology hubs” across the nation. [Maggie Miller, The Hill, May 27, 20]
Moderna down 16% [May 26, 20]
Purinomia Biotech (Woburn, MA; no SBIR), which focuses on biologicals and small molecule development to target key ectonucleotidases for treatment of cancer, autoimmunity, inflammatory disease and metabolic syndrome, raised $2.8M in equity in a $3.8M funding round, according to an SEC filing. [Srividya Kalyanaraman, BostInno, May 26, 20]
GelSight (Waltham, MA; $200K SBIR) announced that it has been awarded a $728,000 [NSF SBIR] grant to develop a compact sensor toolkit that will provide human-like tactile sensing capabilities for robotics.[company press release, May 26, 20] prior funding $10M [crunchbase.com]
Savi Technology (Alexandria, VA; $2.4M SBIR) is working with the Department of Defense to get its logistics tech to the Army National Guard, a 221-unit order amounting to $3.2M in business. It’s one of two multimillion-dollar orders from the DoD, to help get first responders logistics equipment — Savi’s Portable Deployment Kit, as it’s called — amid the coronavirus crisis. The other? The Army Reserve’s $5.1M order for 354 units [DCInno, May 26, 20]
Xeris Pharmaceuticals (Chicago, IL; no SBIR) up 28% [May 22, 20], a specialty pharmaceutical company leveraging its novel formulation platforms to develop and commercialize ready-to-use injectable and infusible drug formulations, today announced positive findings from the outpatient stage of a Phase 2 proof-of-concept study of its developmental ready-to-use (RTU) glucagon in patients who experience postprandial hypoglycemic episodes following bariatric surgery. [company press release, May 22, 20]
Zynerba Pharma up 18% [May 22, 20]
AMAG Pharmaceuticals has completed the sale of its rights to vaginal pain relief drug Intrarosa to Millicent Pharma Limited. The sale is worth up to $125M. [company press release, May 21, 20]
Biotech Day One Pharmaceuticals (Menlo Park, CA; no SBIR) debuts with $60M to change cancer care—starting with children. The drug has been tested in more than 250 patients, adults and children, and it’s in an investigator-sponsored trial testing it in children with relapsed gliomas. [Amirah Al Idrus, Fierce Biotech, May 21, 20]
SQZ Biotech (Watertown, MA; $1.7M SBIR) a clinical stage cell therapy c ompany developing innovative treatments for multiple therapeutic areas, announced the completion of a $65 million Series D preferred stock financing. [company press release, May 18, 20] total funding $166M [crunchbase.com]
Atea Pharmaceuticals (Boston, MA; no SBIR), a biopharmaceutical company engaged in the discovery and development of next-generation therapeutics for severe human viral infections, today announced a $215 million Series D financing [company press release, May 20, 20]
Inflammatory disease biotech Applied Molecular Transport [South San Francisco, CA; no SBIR) aims for $100M IPO to bring its lead program, an oral IL-10 agonist, into phase 2 studies. [Amirah Al Idrus, Fierce Biotech, May 19, 20] total funding $73M [crunchbase.com]
A staggeringly large proportion of people in the so-called "free world" have the emotional maturity of toddlers; they genuinely think their immediate desire is an existential need. Those countries who have done well in this crisis are those with unified, socially-cohesive populations who recognise the simple truth: "What is good for all of us, is probably good for me too." [commenter, NYTimes, May 24, 20]
One of Donald Trump’s special talents is to hold every conceivable position on a given subject at the same time. [The Economist, Apr 18, 20]
Nanoviricides down 16% [May 21, 20]
Mammoth Biosciences (South San Francisco, CA; no SBIR), is leveraging its CRISPR-based DETECTR platform with GSK Consumer Healthcare’s global reach and commercialization expertise to develop an accurate, easy-to-use, fully disposable, rapid and handheld test that consumers and health care providers in clinics can use to detect active SARS-CoV-2, the novel coronavirus that causes COVID-19. [Christine Hall, crunchbase news, May 20, 2020] What happens to test results is unclear.
Aperiomics (Sterling, VA). has teamed up with biotech Antibody Biopharm (Gaithersburg, MD) to offer a rapid antibody test for Covid-19. The Loudoun County diagnostics startup has used its existing testing platform — the same tech involved in its own testing kits — in its Northern Virginia lab to validate and, now, begin offering the test to other laboratories that meet Clinical Laboratory Improvement Amendments, or CLIA, requirements. But the partners still need a nod from the FDA to administer the test as a point-of-care diagnostic given by doctors and other health care providers, which Aperiomics said it expects within two months. [DCInno, May 21, 20]
[DOD] has shelved some of its most ambitious laser plans in order to focus on getting fiber lasers up to a power level where they will actually be useful. especially for lasers on planes to shoot down ICBMs, says Mike Griffin, top DOD science leader and former 1990s overseer of Stars Wars tech group that contained my SBIR program. [Patrick Tucker, DefOne, May 21, 20]
The annual DOD budget battle is on, with a request for $700+B, to do what? We are pulling out of our international role of the hegemonic world organizer and defender. East Asia will have to defend itself from the expanding regional hegemon. World shipping powers will protect the sea lanes. The US will defend itself from Mexican border invasions with a magic wall. And taxes can be cut for the abused wealthy. We used to call that a peace dividend, especially in 1992 when the Bush 41 establishment, and then Clinton, discovered the use of SBIR for dual-use technology.
Act in haste. Hundreds of millions of dollars in unemployment funds were lost to fraud even as jobless claims soar. [New York Times, May 22, 20] A law passed in haste, to be admininstered by an Executive Branch stuffed by loyalists nto the Grupenfuhrer, with control devolved to private enterprise sound like something right of the 19th century. Act in haste, repent at leisure.
For Spy Agencies, Briefing Trump Is a Test of Holding His Attention [NY Times, May 22, 20] When your audience is only thinking of what he will say next, he may miss the message about a possible pandemic. You, of course, will be blamed when it happens.
Liquidia Tech up 18% [May 20, 20]
Vir Biotech up 17% [May 20, 20]
Immunogen up 16% [May 20, 20]
Novavax filed a prospectus to sell up to $250 million of shares of common stock as it prepares to scale up production of its coronavirus vaccine candidate. [yahoofinance.com, May 20, 20]
HotSpot Therapeutics (Boston, MA; no SBIR) a biotechnology company pioneering the discovery and development of first-in-class allosteric therapies targeting nature’s regulatory sites, announced the completion of a $65 million Series B financing. .... to realize our vision of designing and developing first-in-class allosteric medicines,” said Jonathan Montagu, CEO and co-founder [company press release, May 21, 20]
news and views about government programs, politics, attitudes ...1996-1997; 1998; 1999; Y2K; 2001 , 2002-2003 ; 2004-5; 2006; 2007-08 2009-2010; 2011-2012; 2013-14 ; 2015; 2016; 2017-18; 2019-20
BMDO/ MDA including SBIR the doings of star wars
Miscellaneous Stories 1996-1997; 1998-1999; 2000-2001; 2002-2003 ; 2004-5 ; 2006; 2007 2009-2010 ; 2011-2012; 2013-2014; 2015; 2016; 2017
IPO and Venture Markets 1996-1998 .... 1999-2005 ... 2006-present
Quotes steal them if you like
Note: in these old stories, many links are dead, obsolete, or missing
Stories about companies; 1-Al .. Am-Az .. B .. C ... D-E .. F .. G-H .. I-J .. K-L .. M ... N-O ... P ... Q-R .. S1-Se .. ... Sf-Sz .. T-U .... V-Z
10 Kardiac Devices .... 10X Genomics ..... 1366
Technologies ... 1st Detect ...
21-Century Silicon ... 21st Century
Systems .... 23andMe ... 24M Technologies
... 30
Second Software ... 360fly ..... 3Bar Biologics .... 3C Semiconductor
... 3DEO .... 3D Glass Solutions ..... 3Dnamics ..... 3D
Robotics .... 3D Systems
..... 3D Technology
Laboratories
.... 3F ... 3iNanotech .... 3PrimiR ...
3Scan ..... 3-V
Biosciences
.... 3VR ... 410 Medical Innovation .... 454 Life Sciences .... 4C
Medical Technologies .... 4D Molecular Therapeutics ..... 4s3
Bioscience ... 5D Robotics
..... 7AC
Technologies ... 89Bio ... 908Devices ... 9Mile Labs
A10 Networks ... A123Systems ... A4 Pharma .... A&G
Pharmaceutical ... Aastrom
Bioscience
.. Abacus Technology ... ... Abaxis .... Abcombi Sciences
.....
Abeona Therapeutics
..... AbGenomicsInternational ..... Abilitech
Medical ... Abiomed ... Ablative Solutions ....
Ablexis
...... ABL
Technologies .... Abpro
Therapeutics ..... AbSci .... Absorbent
Materials ... Abundant Robotics ..... AbVitro ...
Acadia Pharma ... Acambis
.. Accel Diagnostics ..... Acceleron Pharma
... Accelrys
... Accentia
BioPharmaceuticals ... Accent Therapeutics ..... Accera ....
Access Pharmaceuticals
...
Access
Scientific .... Access Vascular ... Accion Systems .....
Accumetrics
... AccuraGen ..... Accurate
Automation
.. Accuray ... Accuri Cytometers
... Acelerox ....
Acelity .... AcelRx
Pharmaceuticals ...
Acera Surgical .... Acer Thrapeutics .... Acetylon
Pharmaceuticals ... Achaogen ... Achates
Power .....
Achillion
Pharmaceuticals ... ACIST Medical Systems .... Acorda
Therapeutics
... Acorn
Cardiovascular ... Acquia .... AcroMetrix
... AcryMed ...
ActaCell ... Actasys .... ACT Biotech ... Active
Power ...
ActivBiotics
... ActivMedia Robotics .... Acton Pharmaceuticals
...
Actuality... Actuate
Therapeutics .... Acucela ... AcuFocus ....
Aculight
...
Acumentrics ... AcuraStem .... Acutus Medical .... Adamas
Pharmaceuticals ......
Adamis Pharmaceuticals
... Adapteva .... Adaptimmune Therapeutics .... Adaptive
Biotechnologies ..... Adaptive
Computing
... Adaptive
Phage Therapeutics ..... Adaptive TCR ... Adarza BioSystems
.....
Addiction
Therapeutix
...
Addrenex Pharmaceuticals ... Adelor ... Adenosine
Therapeutics
... Adesto Technologies .... Adeza Technologies ... Adherex
Technologies ... Adhesys Medical .... Adial Pharmaceuticals .... Adicet
Bio .... AdiMab
... ADispell ... Adlyfe .... ADMA
Biologics .... Admittance
Technologies
.... Admune Therapeutics ..... Adnexus
Therapeutics ... Adrenergics .... Advanced
BioHealing ... ADS Biotechnology ... Aduro BioTech
.... Advanced Animal Diagnostics .... Advanced Biologics ..... Advanced
Bionics
... Advanced Cell Diagnostics ... Advanced Cell
Technology (now sub to Bio-Techne) ... Advanced Ceramics
.... Advanced
Circulatory .....
Advanced Countermeasures
Systems ... Advanced Diamond
Technologies .... Advanced Electron Beams ...
Advanced Fuel
Research ...Advanced Life Sciences ... Advanced Lighting
Technologies ... Advanced Liquid Logic
...
Advanced Magnetics ... Advanced Photonix ....
Advanced
Programming Concepts ... Advanced Receiver
Technologies .... Advanced Scanners .... Advanced Scientific Concepts
..... Advanced Targeting
Systems
.... Advanced
Technology
Materials.(ATMI) ... Advanced Uro-Solutions ..... AdvanDx ...
Advantic ..... Advaxis ..... Adventrx
... Adverum Biotechnologies ..... Advion BioSciences
...
Adynxx ...... Aegea
Medical ... Aegerion Pharmaceuticals .... Aeglea
BioTherapeutics
Holdings ..... Aerial BioPharma .... Aerie
Pharmaceuticals
... Aerin Medical ..... AerisPhotonics ...... Aerius
Photonics
... Aerodyne Research ... Aero Farms System
... Aerovel ..... AeroVironment ... Aerpio
Therapeutics .... AesRX
...
AETC ... Aethlon Medical
... Aethon .... Aevi Genomic Medicine .....
Affectiva
.... Afferent
Pharmaceuticals ..... Affigen .... Affinia Therapeutics< .....
Affinimark
Technologies
... Affinity BioReagents ... Affinium
Pharmaceuticals ..... Affinivax .... Affomix ....
Affymax ....Affymetrix ... aFraxis ... AgBiome ..... AgeneBio
....
Agennix ... Agenovir ..... Agenus .... Agere
Pharmaceuticals ..... Agile
Materials
... Agile
Planet ... AgileSwitch .... Agile Therapeutics ....
Agility
Robotics ..... Agilis Biotherapeutics .... Agiltron...Agilvax ....
Agilyx ....
Aagios
Pharmaceuticals... AgraQuest .... Agritope... Agrivida
... Agro Biosciences .... Aguila
Technologies.....Ahura Scientific.... Aiko Biotechnology
... Aileron Therapeutics .... Aimmune Therapeutics
(formerly
Allergen Research) ..... airtricity... Airware .... Airxpanders ....
Airway Therapeutics .... ait laboratories... Akadeum Life Sciences ....
Akamai
Physics
Akarna
Therapeutics
..... Akashi Therapeutics ..... Akcea Therapeutics ..... Akebia ....
Akero Therapeutics ... Akermin ..... Akers BioScience ..... Akita
Innovations
... Akouos ....
Akrevia Thera {now Xilio Thera) .... Akron
Polymer Systems ..... Akron Surface
Technologies ..... Akros Medical ....
Alabama
Cryogenics ... Alafair Biosciences .... Albany Molecular
(AMRI) ...A?
nanotech .... Alcon .... Alcresta
.... Aldagen
... Aldatu Biosciences ..... Aldea
Pharmaceuticals
... .
Alder biopharma Aldevon ..... Aldeyra Therapeutics (formerly
Aldexa Therapeutics) .... Alector .... Alexar Therapeutics .....
Alexion
... ....Alexza ....
Alfalight.... Algaeventure Systems ... Algenetix .... Algeternal
.... Algorithmia ..... Alien Technology
.... Alimera sciences.... Alios BioPharma ....Aliva
biopharmaceuticals ..... AliveGen .... Alivio Therapeutics .....
Alkermes...
Alkeus Pharmaceuticals ...
Allakos ... Allcast ....
Allegro Diagnostics ....
Allegro
microsystems ... Allena Pharmaceuticals .... Allergy Amulet
.....
Allerquest
.... Alleviant Medical .... Allied BioScience ..... Allied Minds ....
Alliqua .... Allos
Alloy Polymers .... Alloy
Surfaces .....
Allurion Technologies ... Allylix ... Ally Therapeutics ....
Alnara Pharmaceutical
...
Alnylam... Alper Biotech ... Alphabet Energy .... AlphaCore Pharma ...
Alphamed.... Alphatec
Holdings .....
Alphavax ... Alpine Biosciences .... Alpine Data
Labs .... Alpine Immune Sciences ..... Alseres ..... Algeternal
.... Alta Devices ... AltAir Fuels ... Altair
Therapeutics
... Altamira Technologies .... AltaRock
... AltheaDX .... Althea
Technologies ... Altimmune ..... Altor ...
Altra ...
Altura Medical ... Altus Pharmaceuticals ...
ALung
Technologies
... Alvine Pharmaceuticals .... ALX
Oncology .... Alycone
Lifesciences .... Alzeca ..... AMAG Pharmaceuticals
... Alzheon ..... Amaranth Medical .... Ambarella .....
Amberwave
... Ambiq
Micro ....
Ambit
Biosciences .... AMBP
Technology ... Ambri .... Ambrx ...
Ambry .... Ambys Medicines .... Amendia .... American Bionics .....
American
Gene Technologies International .... American Lithium Energy ....
American Medical Systems ....
American Science and Engineering
... America Stem Cell, now Targagyme .... American
Superconductor
... American XTAL .. Ames
Technology ... Amgen ... Amicus Therapeutics .... Amionx ..... Amnis
...
AMO
Pharma ..... Amphivena Therapeutics .... Ampio Pharmaceuticals .....
Ampla
Pharmaceuticals ... Amplimmune .... Amplyx Pharmaceuticals
.....
Amprius .... ARMO
BioSciences .... Amunix Pharmaceuticals .... Amylin
Pharmaceuticals ... Amylyx ..... Amyris
Biotechnologies ... AN2 Therapeutics .... Anacor
Pharmaceuticals ...
Anadys
Pharmaceuticals ... Anakim Biologics ....
Analog Computing
Solutions .... Analytical Space ..... AnaptysBio
... Anavex Life Sciences .... Anchor Therapeutics ...
Ancora Pharmaceuticals
... AnDAPT ..... Anexon .... Anew Optics ... Angeion ...
AngioDynamics
... Angiologix ... Angstrom Medica .... Angstron
Materials
... Animalgesic Labs .... ANI Pharmaceuticals ...
Animetrics .... Anivax .... Anivive Therapeutics ..... Annexon
Bioscience ..... Annovis Bio .... ANP Technologies
..... Ansoft
... Ansun Biopharma (formerly NexBio) .... Antegrin
Therapeutics
..... Anthera
Pharmaceuticals .... Anthos Therapeutics .....
Antigenics ... Anue Systems ... Anulex Technologies
... Anybots ... AOBiome Therapeutics
(formerly
Nitrocell) .... AOptix Technologies
... Aortica ..... APA
Optics (Enterprises) ... Apellis Pharmaceuticals
.....
Apexigen ... Aperiomics .... Aperion Biologics .... Aphios
... Apic Bio .... Apieron ... Apnex Medical
... ApniCure .....
ApoCell ....
ApoGen Biotechnologies .... Apollo
Diamond
... Apollo Endosurgery ... Apollomics
(previously CBT
Pharmaceuticals) .... Apoplogic Pharmaceuticals
... Applied Biomolecular Technologies .... Applied Biosystems
.... Applied Defense Solutions ..... Applied DNA
Sciences .... Applied Genetic Technology ... Applied Nanotech
....
Applied
NanoWorks ... Applied Optimization ..... Applied
Optoelectronics ... Applied Physical Electronics ...
Applied Physical Sciences ... Applied Precision ..... Applied
Proteomics ..... Applied Quantum Technologies .... Applied Quantum
Technology
.... Applied Research Associates
... Applied
Science and Technology ... Applied Signal
Technology
... Applied Therapeutics ...... AppThwack ....
Aprea Therapeutics .... Aprecia Pharmaceuticals ....
Apricus
Biosciences
... APS BioGroup .... Apse .... Aptalis Pharma .... Aptevo
Therapeutics .....
Aptima ... AptamiR
Therapeutics .... Aptinyx .... Aptose
Biosciences .... Aptus
Endosystems ... Aquaback Technologies ...
Aqua Bounty
... Aquacue .... AquaHarmonics ..... Aqua Metals .... AquaMost
...
Aquarius
Technologies ... Aquestive Therapeutics ....
AqueSys
... Aqueti .... Aquion .... Aradigm ....
AragonPharmaceuticals
...
Aratana
Therapeutics ..... Arbor Biosciences< ..... Arbor Biotechnologie
..... Arbor Pharmaceuticals
...
Arbovax
... Arbutus BioPharma (formerly OnCore) ..... Arca Biopharma ....
Arcadia Biosciences ..... Arcadia Pharma ..... Arcantatura...
Archemix
... Arcellx .... ArcherDX ......Arch Innotek ..... Arch
Oncology ..... Arch
Therapeutics
... Arctic Sand Technologies .... Arcturus Therapeutics ....
Arcus Biosciences ..... Arcutis Biotherapeutics .... Ardea Biosciences
...
Ardelyx .... Ardian .... Arena Pharmaceuticals
... Argentum ..... Arginetix
... Argo AI ..... ArgonST ... Argos Therapeutics ... Aria CV
...
Ariad Pharmaceuticals .. Aria Insights (previously CyPhy
Works) .... Ariosa Diagnostics ..... Arista MD
....
Arista Networks .... ARIZ Precision
Medicine .... Arkansas Power Electronics ..... Arkuda Therapeutics ...
Armadillo Aerospace
... Armata
Pharmaceuticals .... Armetheon .... ARMO BioSciences .... Armonica
Technologies .... Armorworks
... Armune BioScience ..... Aro Biotherapeutics
.... Aronora ..... Arpeggi
.... ArQule ... Arrakis Therapeutics .....
Array ... Arranta Bio .... Array Information
Technology ..... Arresto
Biosciences .... Arrien Pharmaceuticals ... Arrivo
BioVentures ..... Arrowhead Pharmaceuticals ..... Arrowhead
Research .... Arsanis ... ArsenalBio ...
Arsenal Medical
.... Arstasis ... Artel .... Arteriocyte
... Arterys
..... ArthroCare
...
Arthrosurface ... Artisan Pharma ... Artizan .... Artrility
Medical ..... ArunA Bio .... Arvegenix ..... Arvinas .... Arxan
Technologies .... Aryx
Therapeutics ..... Aryx
... Arzeda
... Asana Medical (now Regentsys) .... Asante Solutions .....
Ascelegen
Therapeutics .... Ascension
Orthopedics ... Ascent
Solar Technologies ....
Ascent
Therapeutics .... AsclepiX Therapeutics .... Aseptia .... Ash
Access Technology .... Asklepios
Biopharmaceutical .... AstroWatt .... Aspen Aerogels
.... AspenBio
Pharma .... Aspen
Neuroscience .... Aspen Products Group ....
Aspen Technology
... Aspyrian Therapeutics .... Assurex Health ..... Astex
Therapeutics ...
Asthmapolis .... Astralux
... Astrobotic Technology ....
Astronautics Corp. of
America ... AstroPower... AstroTerra ..
Astrum Solar ... Astute
Medical ....
Astute Medicales ... Asuragen
... Atacama ..... Atara Biotherapeutics ..... Ataxion ....
Athenex
(formerly
Kinex) ..... Athenix
... Athens Research ..... AtheroGenics ... AtheroMed ....
Athersys .... ATI Industrial
Automation
... Atlantia ... Atmocean .....
Atmospheric Glow
Technologies ...
Atomate ... Atomic Medical Innovations .....
Atomometrics
... Atomwise ..... Atoptix .... Atossa
Genetics
... Atreaon ....
Atreca .... Atreon Orthopedics
..... AtriCure ... Atrium
Medical ... ATRP Solutions ... aTyr Pharma .....
Audentes
Therapeutics ..... Audience
... Augmenix
.... AUM
Cardiovascular ... Aura Biosciences ....
Auris Health .... Auris Medical .... Auris Surgical Robotics
..... Aurora
Algae ... Aurora Flight
Sciences ....
Aurora
Imaging Technology ...
Aurora Spectral Technologies
... Auspex
Pharmaceuticals ... Ausra ... Auterra
.... AuthenTec .... Autolus Therapeutics .... Automated Dynamics ...
Automated
Medical Instruments .... Autonet ... Aushon
Biosystems ... AutoGenomics .... Autonomic Materials
.... Autonomic Technologies ..... Autonomous Technologies
....
Auxilium
Pharmaceuticals ... Avalanche
Biotechnologies .... Avalyn Pharmaceuticals .... Avanir Pharmaceuticals
... Avant Immunotherapeutics ... Avanti Metal ...
Avaxia
Biologics ... Avedro ... Avelas Biosciences ....
Aveo
Pharmaceuticals
... Avery Therapeutics ..... AveXis .... Aviation Resources
Delaware .... AVI
BioPharma ... Avici Systems ... AvidBiotics
.....Avidity
Biosciences .... Avid
Radiopharmaceuticals
... Avila Therapeutics ... Avinger ....
... Aviragen Therapeutics (formerly Biota
Pharmaceuticals)
..... Aviron ..... Avisa Pharma .... Avita Medical Americas .....
Avitude .... Avrobio
..... AVT Simulation .... Aware ... Axcella Health (was Pronutria)
.....
Axelo .... Axerion Therapeutics
... Axial
Biotech .... Axial Biotherapeutics ..... Axion BioSystems
.....
Axion Power
... Axis Clinicals .... Axis
Semiconductor
... Axium Nanofibers ...... Axium Pharmaceuticals .... Axogen
.... Axonia Medical ....Axonics Modulation Technologies
Axsome Therapeutics ..... Axsun Technologies ... Ayasdi
..... Azaya
Therapeutics ... Azelon Pharmaceutical ... Azimuth
.... Azitra ..... Aziyo Biologics ..... Azure Biotech ..... AzurRx
BioPharma
Baby Genes .... Bacterial Robotics .... BacterioScan ....
Baebies
..... Bagaveev
.... Ballard
Power ... Bamboo Therapeutics ..... Bandgap ... Banner Life
Sciences ..... Banyan Biomarkers ... Bardy
Diagnostics .... BarioSurg ..... Baryonyx .... Barrier
Therapeutics ... Baseload Renewables .... Basis
Science
.... Bastion
Technologies
.... Batu Biologics ..... Bauhaus Software ..... Baxano ...
Baxano Surgical .... BayoTech ..... Beacon Biomedical ..... Beacon
Power ... Beam Therapeutics ..... Beat
Biotherapeutics .... Beeco
... Behavioral Recognition Systems .... Bellerephoon
Tera .... Bellicum
Pharmaceuticals .... Belmont Instrument ....
Benchmark
Automation ... BeneChill
... Benefuel ... BeneVir Biopharm ....
Bennett
Aerospace .... Benson Hill
Biosystems ..... Benvenue
Medical .... Berg .... BerrieHill
Research
... BESS Technologies .... BetaBatt
...
BetaLED ....
LEDBG Medicine
... Bettergy .... Bexion Pharmaceuticals .... Bina
Technologies .... Bind
Bioscience ... Bind Therapeutics .... BinOptics ..... BiO2
Medical
... BiO2
Technologies
...
BioAmber ... BioAdvanTek ... BioAffinity
Technologies .....
Bioanalytical Systems
... BioBehavioral Diagnostics ... BioBridge
Global
..... BioCardia .....
BioCentra Molecular Innovations ..... Biocept
...
BioChemics ..... BioClin Therapeutics .... Bicycle Therapeutics .....
Bien-Etre
Labs ..... BioCold Genesys .... Bioconnect Systems .... BioConsortia
..... BioCritica
... BioCryst Pharmaceuticals ...
BioDelivery Sciences ... Biodesix .... BioDirection ..... BioDtech ...
BioFactura ... ..... BioE ...
BioFire .... BioFluidica ..... Biogenic
Reagents
.... BioGreenChoice ... BioHaven Pharmaceuticals ..... Bioheart
...
Biohelix ... Bio-Imaging Technologies
...
Bioincept .... Biointervene .... BioKier ..... Biolex Therapeutics
... BioLife4D ..... BioLink Life
Sciences
... Biolinq (formerly Electrozyme) .... Biologics
...
BioMagnetic Solutions ....
BioMarin
Pharmaceutical
... BioMarck
Pharmaceuticals .... bioMASON ..... Biomatrica ...
BioMedical
Enterprises
... Biomedical Sciences ..... Biomedical
Structures ...
BioMedix .... Biomeme .... Biomerica .... Biometric
Signature
... BioMimetic Therapeutics
... BioMotiv .... BioNano
Genomics ... BioNanomatrix ... Bionostics
Holdings
... Bio-Path Holdings ..... Biophan Technologies
... Biophysical ... BioProcessors ...
Bioptigen
... Bioptix .... BiOptix Diagnostics ..... BioPulping
International
...
Biopure ... Biorasis ..... BioRelix ... BioResource
International
...
BioRestorative Therapies (formerly Stem Cell Assurance) ....
BioSante Pharmaceuticals ... BioScale
.... BioSense
Technologies ... BioSensics .... BioSentinel
Pharmaceuticals
... BioSig Technologies ..... Biosortia Pharmaceuticals ....
BioSphere Medical
.... Biostage (formerly Harvard Apparatus
Regenerative
Technology) ..... BioStructures .... Biosurfaces .... Biosym
Technologies later Accelrys
....
BioSystem
...
Biota Pharmaceuticals .... Bio-Techne ..... BioTechnique ....
BioTechPlex .....
Biotectix
....
Biotel
.... BioTelemetry (formerly CardioNet) ..... BioTex
....
Biothera
... BioTheranostics ... Bio Time ...
Biotix
... Biotronic NeuroNetwork ..... Biotronik ....
BioTrove
... BioVaxys .... Bioventus ..... Biovest International ....
BioVex
... BioVirtua ..... Bird Rock Bio (formerly RuiYi) .....
Birich
Technologies .... Biscayne Neurotherapeutics ..... Bitstream
... Black
Diamond Therapeutics .... Black-I Robotics
... Black Sand ... BlackThorn
..... BladeLogic
... Blasch Precision Ceramics .... Blaze
Bioscience ... Blend
Therapeutics ....
BL Healthcare ... Block Engineering ...
Bloom Energy
... Bloo Solar ..... BluDiagnostics ..... Blue Belt
Technologies
...
Bluebird
bio ...
BluDiagnostics .... Bluefin Robotics ... Bluegrass
Proteins
.... Bluegrass
Vascular
Technologies .... Blueprint
Medicines ...
BlueRock Therapeutics ..... Blue
Sky Batteries ... Bluewater Bio International ... Blue Water
Vaccines .... Bolder Surgical ... Bolt
Biotherapeutics .... Bolt Threads ....
Boom Supersonic ..... Boragen .... Boston Biochem
... Boston Biomedical ... Boston Dynamics
...
Boston Engineering ... Boston Micromachines ... Boston
Micromachines (formally Boston
Electrometallurgical .... Boston-Power
...
Boston
Therapeutics ... Bot Dolly .... Boundless
... Boundless Bio ... BoXZY
..... Braeburn Pharmaceuticals ..... BrainCells
... BrainScope .... Brain Sentry ....
Brain Tunnelgenix
Technologies .... BrainXell ..... Branch Medical Group ..... Brayton
Energy
.... Breathe
Technologies ... Breethe .... Breonics ...
BreviTest
Technologies
..... Brewer
Science ... Brickell Biotech .... Bridger Photonics .... Bridgelux
... Brightsource Energy ... Bright View
...
Brimrose Corp of America ... Briteseed .... Brock Rogers Surgical
...
Bromium
.... Brooks
Automation ...
Bruker Daltonics .... Buffalo BioLabs ..... Burl
Concepts
..... Burr Oak
C12 Energy ... C2Sense .... C3Nano
... C4 Therapeutics .... C8
Sciences ....
C9 ... Cabaletta Bio .... CABG Medical ....
Cadence Pharma ....
CadheRx
Therapeutics
.....
Caisson Biotech .... Calabazas
Creek
Research .... Caladrius
Bioscience ... Cala Health ..... Calando
Pharmaceuticals
... Calbiotech .... Calera ... Caliber Biotherapeutics ....
Calibra
Medical ... Calient ... California Wave Power
Technologies ..... Calimmune ..... Caliper Life Sciences
....
CaliSolar ... Calistoga Pharmaceuticals ...
Calithera
BioSciences .... Calixa
Therapeutics ... Callidus Biopharma ... Calporta
Therapeutics
.... Calspan .... Caltech Metals ... Calysta .... Calyxt ..... Cambrian
Innovation ... Cambridge
Endoscopic Devices ... Cambridge Heart
.... Cambridge
Research & Instrumentation ... Cambrios
Technologies .... CAMX ..... Candela Laser ....
Cancer
Genetics .... Cancer Prevention
Pharmaceuticals .... CanDiag .... Canopy Biosciences ..... Capesym
... Capillary
Biomedical ..... Capio Biosciences .... Capnia
... CAPP Medical ..... Capricor Therapeutics .... Cara
Therapeutics .... Carbon .....
Carbon
Design
Systems ... Carbtex Technology
.... Carbylan Therapeutics ..... Cardeas
Pharma ....
CardiacAssist ..... Cardiac Concepts ...
Cardiac
Dimensions
... Cardiac Science ..... Cardialen ..... CardiAQ Valve
Technologies ... Cardica
... CardioDx
... Cardio Flow ..... CardioFocus ... CardioInsight
Technologies .....
Cardiokinetix ..... CardioMag ... CardioMEMS .... Cardionomic ....
CardioNXT ..... Cardiorobotics
...
Cardiosolutions ... Cardiosolv .... CardioSpectra ... CardioTech
... Cardiovate ..... CardiOx ...
Cardioxyl
Pharmaceuticals
.... CareDx (formerly XDx) .... Caribou Biosciences
.....
Carigent Therapeutics .... Carisma Thera (formerly CARMA Therapeutics)
..... Carlsme .... Carmot Therapeutics
..... Carnegie Robotics
.... Carnegie Spee .... ... .... Carnot BioSciences ....
CaroGen .... Carter Aviation Technologies .... Carticept
Medical ... Cartiva ..... Cascade Designs ...
Cascade
Microtech
... Cascadian Therapeutics (formerly Oncothyreon) ..... Casma
Therapeutics .... Castle Pharmaceuticals .... Castle Creek
Pharmaceuticals
Catabasis Pharmaceuticals ... Catadon
Systems ... Catalyst Biosciences ... Catalyst Pharma
.... Catalytic Innovations ..... Catalyze ..... Catelectric
.... Cebix .... Cedarburg Pharmaceuticals .... Cedilla
Therapeutics ..... CeeTox
... Celadon ... Celator Pharmaceuticals
... CelcuityCeldara Medical ..... Celladon .... Cellara .... Cell Care
Therapeutics ..... Cellceutix
.... CellCyte
Genetics ... Cell Design Labs ..... Celldex Therapeutics
... ..... Cellectar ... Cellerant
Therapeutics
... Celleration .... Cell Genesys ... CellRight
Technologies
..... Cellular
Bioengineering
...
... Cellular Bioengineering ..... Cellular Biomedicine Group
.....
Cellular Dynamics International .... Cell>Point
.... CellSavers ..... Cellscape .... Cellscript
..... Cell
Signaling Technology ...Cell
Therapeutics (now CTI
BioPharma)
... CellTraffix ... CeloNova Biosciences
..... Cel-Sci
.... Celsion ...
Celtaxsys ..... Celula..... Celularity ..... CellzDirect ...
Cempra Pharmaceuticals.
.... CeNeRx
BioPharma ... Censa Pharmaceuticals .... Centocor ....
Centrexion Therapeutics .....
Centrose ... Centice .. Century Therapeutics .... Centritec
Seals ... Cephalon
... Cepheid
... Cephalon ... Ception Therapeutics
... Cequent
Pharmaceuticals ... Cerebras Systems ..... Ceradyne ...
Ceramic
Tubular Products .... Ceramitron ... Cerapedics
.... Ceramatec
... Cerevast Therapeutics .... Cerealus Holdings
... Cerebral
Therapeutics .... Cerecor .... Ceregene ...
Cerahelix
.. Ceres Nanosciences ..... Cerevance .... Cerexa
.... Cerion
Enterprises ...
Cermet ... Cernostics ..... Cerulean Pharma
... Cerus ... Cervel Neurotech .... Cesca
Therapeutics .... Ceterix .... Orthopaedics ... CFD Research ..
CFX Battery
.... CGI Pharmaceuticals ... ChaCha
... Chantilly BioPharma .... Chapman
Innovations ... Charles River Analytics .... Charles
River Lab ... Charter Medical ..... Chase Therapeutics ....
CHASM
.... Chatham
Therapeutics ..... Checkerspot ..... Chemat ... Chembio Diagnostic
Systems .... ChemImage ... Chemir Analytical
Services ...
ChemoCentryx
... Chemtura ....
Chesapeake Sciences
...Chesson Labs ... Chiasma .... Chimera
Bioengineering ..... Chimerix
... Chlorogen ... Choice Therapeutics
... Chondrogenics
... Chordia
Therapeutics .... Chorum Technologies
.... ChromaCode
..... ChromaDex
..... Chronix
Biomedical
... Chrysalis BioTherapeutics .... Cibus
Global
... Cidara Therapeutics .... Ciena
....Ciencia ...
Cilion .... CimaBay Thera ..... CinCor Pharma .... CinRx ....
Ciranova
... Circle
Technologies ..... Cirius Therapeutics ..... CivaTech
Oncology ... Civetta Therapeutics .... .... CiVi Biopharma .....
Civitas Therapeutics
..... Claret Medical .... Clarassance ..... Claresta
Solutions
.... Clark-MXR ...Claros
Diagnostics
.... Clean Diesel
Technologies ... Clear Catheter Systems .... ClearCount
Medical
Solutions .... ClearEdge
Power .... Clear Guide Medical .... Clearside
Biomedical ... Cleave Biosciences ... Cleveland BioLabs ...
Cleveland
Polymer Technologies ..... CleverSet ... Clinical Data
... Cloudant ... CloudMade ... Cloud
Pharmaceuticals
(formerly Teradiscoveries) .... Clovis
Oncology ... Clovis Tech ..... CMC Biologics .... C-Motive Technologies
.... CoAdna,Holdings ..... CoAxia ....
Cobalt Biofuels ... Cocoon Biotech .... Cocrystal
Discovery ... Coda
Biotherapeutics .... Codexis
... Co-Diagnostics< ... Codiak
BioSciences ..... Codon
Devices ... Co-D Therapeutics .... Cofactor
Genomics ....
Cogenra .... Cogentix Medical ..... Cognex
...Cognition
Therapeutics .... Cognitive Code
... Cohera
Medical .... Coherus Biosciences .... Cohesive
Technologies ... ColdQuanta .... ColdWatt ... Collagenex
Pharmaceuticals ...
Collegium Pharmaceutical ... CoLucid Pharmaceuticals
... Columbia Labs ..... CombiMatrix ...
CombinatoRx
..... Combined Energies .... Combinent
BioMedical Systems ... Comet Therapeutics .... Comfort Motion
Technologies
...
Commonwealth Biotechnologies ... Commonwealth
Fusion Systems ..... Compact Membrane Systems ...Compass
Therapeutics .... Compellent Technologies ... Compendia
Bioscience
.....
Complete
Genomics ....
Complexa
..... Conatus
Pharmaceuticals ... Concert
Pharmaceuticals
.... Concordia Fibers ...Concurrent Technologies ...
Conductus
.. Confluence Life Sciences ..... ConforMIS ...
Cognigen
.... Conispire
.... ConjuGon .. Connecticut
Valley Bindery ... Consonus Technologies
...
Constellation
Pharmaceuticals .... Context Therapeutics ..... Contour Energy
Systems ControlRadSystems ..... Convelo
Therapeutics ....
Conventus
Orthopaedics ..... Convergen
... ConverGene .... Convio .... Convoy
Therapeutics
.... Cool-Bio
.... CoolCAD Electronics .... CoolChip Technologies
....
Cool Earth
Solar
.... Cooligy ... CoolTech .... Corbus
Pharmaceuticals
..... Corcept
Therapeutics
...
Cordex Systems .... CoreStreet ... CoreTek ...
.Corgenix
Medical
... Corindus ....Corinthian
Ophthalmic ... Corium International .... Corixa
....
CorMatrix
Cardiovascular
.... Cormedix ... Cornami ..... Cornerstone Research
... Cornerstone BioPharma then Cornerstone
Therapeutics
..... Cornerstone Therapeutics .... Coronado
Biosciences ... CorQuest Medical ..... Correx ... Corridor
Pharmaceuticals
... Cortana ..... Cortendo AB ..... Cortexyme ....
Corvidia
Therapeutics ..... Corvus
Pharmaceuticals
..... CosmosID ..... CoStim Pharmaceuticals
.... Cougar
Biotechnology ...
Coulbourn
Instruments .... Coulter Pharmaceuticals ... Cour
Pharmaceutical
Development .... Coverity ..... Creare ...
Creative
Hybrid Solutions .... Creatv MicroTech .... Cree
Research ... Crescendo Bioscience .... Crinetics
Pharmaceuticals
....
CrispTek .... Critical Therapeutics .... CritiTech
... Crossbar .... Cross Current ..... CrossFire
... Cruise Automation .... Crux Biomedical
...
CryoCor ...
CryoLife ... Cryomedical Sciences ..... Cryptonite .....
Crystal
IS
...
Crystal Systems ... Crystallume ... CSA
Engineering ... CS-Keys ... CTD Holdings
..... CTI
BioPharma (formerly
Cell Therapeutics) .... Cubist
Pharmaceuticals
... Cue Biopharma .... Cullinan Oncology ..... Cumberland Pharma ....
CuraGen ... Curamir Therapeutics ... Curative .... Current Motor
...
Curtana Pharmaceuticals .... Custom Electronics .... CVD
Equipment ..... CVRx
... CV
Therapeutics ... Cyanotech ..... Cyberdyne .... CyberKey Solutions
... Cyberkinetics Neurotechnology ... Cybernet Systems
... CyberOptics ... Cyclerion
Therapeutics .... Cydan ....
Cygnal
Therapeutics .... Cykloburn
Technologies ..... CymaBay
Therapeutics
.... Cymbet ... CyMedica Orthopedics ..... Cymer
...
Cynosure ... Cyntellect ... Cypher Genomics ... CyPhy Works
... Cypress Bioscience ... Cyrus Biotechnology .....
Cyteir
Therapeutics ..... Cyterix
Pharmaceuticals ...
CytImmune .... CytoBioScience ..... Cytocentrics ..... CytoCore
(formerly Molecular
Diagnostics) ..... Cytocybernetics ..... CytoDyn
.... Cytogel Pharma
.... Cytokinetics
... Cytometix ....CytomX ...
Cytonome
....
Cytori Therapeutics ... Cytophil CytoSolv
... Cytosorbents ..... Cytovas ... CytRx ..... Cytyc
...
CyVek
Fallbrook
Technologies
... Famigo ... Faraday Pharmaceuticals .... Farodox
Energy
Storage
...
FarSounder ... Far-Tech.... FastCAP Systems ...
Fate
Therapeutics
... Fathom .... Fe3 Medical .... FEI ... Femasys
.... Femta
Pharmaceuticals
.... Ferrate
Treatment Technologies ... Ferric Contrast ...... FerroKin
BioSciences ....
Fervo Energy .... Feuz Manufacturing ... FGC Plasma Solutions
..... Fiber and Sensor ....
Fiberight ...
Fiber Materials ... Fibersense ... Fiberstar ....
Bio-Ingredient
Technologies ... Fibertek .... Fibrocell Science
... FibroGen ... Filter
Sensing Technologies ...
Finally Light
Bulb ..... Finch Therapeutics Group ..... FineLine Prototyping ....
Finisar
... Fire Alarm
Specialty Design .....
Firefly
BioWorks ... Firefly Energy .... Firefly LED
...
First Solar ... Fisker Automotive ... Five Prime
Therapeutics .... Flex Biomedical
... Flexion Therapeutics ... Flex Pharma
.... Flextronics
America ....
Flexus Biosciences .... FLIR Systems
.. FloDesign
Wind Turbine ... FlowCardia
...
FlowMedica .... FlowMetric .... Flow Metrix
...
FluGen
... Fluidic Energy ... Fluidigm ... Fluid Innovation
Group
... Fluidnet ... Fluidnet
FluoroPharma
... Fog Pharma ..... Foghorn
Therapeutics .... FokusLabs .... FoldRx Pharmaceuticals
...
Follica ...
Footnote .... Foresight Biotherapeutics .... Forest Devices .... Forge
Therapeutics .....
F-Origin
... Forma
Therapeutics ...
Formlabs
.... For-Robin ..... ForSight Vision5 .... Fortis Therapeutics .....
Forty Seven ..... Forum Pharmaceuticals ..... Forus
Health ... Foster-Miller .... Foundation Medicine
... Fox Chase Chemical Diversity Center ....
Fractal
Antenna Systems ... Fractyl Labs ..... Freedom Meditech
... Free
Flow Power ... Free Form Fibers .... Freenome ..... Froedtert
Health ..... Frontier
NanoSystems ..... Frontier Technology ..... Front Range Biosciences
.... FTL Solar
...
FuelCell Energy
... Fuel Tech
.. Fulcrum Therapeutics ..... Fulgent Therapeutics ..... Full
Spectrum Genetics .... Furiex
.... Fused
Innocation.
...
Fusion
Coolant Systems ... Future Technologies
G1 Therapeutics ..... G3
.... Gadusol Laboratories (aka
Seaceuticals) ..... Galderma .... Galectin Thera ..... Galenea ...
Galena
Biopharma
.... Galera
Therapeutics ..... Galil Medical ..... Galleon
Pharmaceuticals ... GAM Enterprises .... GameSalad
... Gamma Medica Ideas ... Garland
Technology .....
Garwood Medical Devices ..... GATR Technologies ..... G-Con .... Gecko
Biomedical .... Gecko Robotics .... Gel Combs .... Gelesis ...
Geltech ...
Gema Diagnostics .... GEMFIRE .. Gemin X Pharmaceuticals
... Gemmus
Pharma ... Gemneo Bioscience ..... Gemphire Therapeutics
......
Gemstone
Biotherapeutics
..... Gen9 ...
Genaera ...
Genalyte
... Genapsys .... GenAudio .... Gene by Gene .... GeneCentric
Diagnostics
... Genelabs Technologies ... Gene
Logic ... Geneoscopy ..... General Compression
...
General
Pneumatics
..... Generation Bio ..... Generex
Biotechnology ... Gene Security Network .... GeneSegues
Therapeutics ..... GenesisLabs ....
GeneSystems ... Genetesis .... Genetic Networks ..... Genetix
Pharmaceuticals
... GeneTx Biotherapeutics ..... Geneu .... Genia
Technologies
.... GenMark Diagnostics
.... Genoa Pharmaceuticals ..... Genocea
Biosciences
... Genomatica
... Genome Profiling ... GenomeQuest ... Genomic Health
...
Genomind ....
Genoptix
Medical
Laboratory ... Genor ... Genprex .... Gen-Probe
...
GenSpera
.... GenTel BioSciences ... Gentris ... GenturaDx
...nbsp; GenVec ... GenWay Biotech ..... Genzyme .... Geocent
.... Geocove ..... Geomagic
... GeoMed
Analytical ... GeoVax Labs ...
Geospiza
... Germfalcon ..... Geron ...
Gevo
..... GI Dynamics
...
GigOptix
... Gilead Sciences .... Giner . ..
Ginkgo BioWorks
.... Glauconix ..... Glaukos
.... GlideLine
Systems ... Gliknik ... Global Blood
Therapeutics
...... Global Cancer Diagnostics ..... Global Positions ...
Global Blood Therapeutics ....
GlobeImmune ....
Gloucester Pharmaceuticals ... Glowforge ..... GlucaGo ...
GlycoFi
... GlycoMimetics .... GlyGenix ... Glympse Bio
.... Glyscend .....
GlySens
... GMZ
Energy
... GnuBio
.... Goddard Labs .... Goldfinch Bio .....Goodman
Technologies< ..... Good Start Genetics
.... Gore
Photonics ... Gossamer Bio ..... Gotham Biotech .... Gotham
Therapeutics ..... GPC-Rx
... gRadiant Research ... Gradiant ....
GraftWorx
..... Grail ..... Graphene
Energy
... Graphenix Development .... Graphic
Surgery ... GraphLab (now Dato) .... Grassroots Biotechnology
...
Greatbatch
... GrayBug ..... Graybug Vision ..... Great Basin Scientific .....
GreatGrow Maryland ....Great North Lab .... GreatPoint Energy
... Green & Grow .... GreenFuel
Technologies .... Greenlight Biosciences .... GreenMark Biomedical
..... Green Mountain Radio
Research .... GreenSight Agronomics ..... Green Sulfcrete
.....
GreenTech America
... Greenwich Geriatrics .... GridBridge .... Grid
Therapeutics
..... Gritstone
Oncology
..... GRO Biosciences ..... Group14 Technologies ..... Grove
Instruments
... Grow Home Organics
.... GSI Technology ... GT Advanced
Technologies ...
GTC Biotherapeutics ... G-Tech Medical .... GT
Equipment .... GTI
Diagnostics
... GT Medical
Technologies ..... GTx .... Guardant Health .... Guided Surgery
Solutions
....
Guided
Therapeutics
.... .... Guided Therapy Systems ..... Gynesonics .....
G-Zero
Therapeutics
Energy Now ...... H2O
Score ..... H2Pump ...
H2Sonics
.... H3
Biomedicine ... HNC Software ... Halozyme ...
Hana
Biosciences .... Hansen Energy and Environmental
....
Hansen Medical ... Haplogen Genomics ..... Harbor
Technologies .. Hardcore Computer ... HarkerBio .... Harmony
Enterprises ....
Harpoon Medical .... Harpoon Therapeutics .... Harvard Apparatus
Regenerative Technology .... Harrisvaccines .... Harvard Bioscience
... Harvest Automation .... Harvest Power ...
Harvest Technologies .... HDL Therapeutics .... Healionics
.. Health Diagnostics
Laboratories .... HealthMyne ....
Healthtronics
.... Hearforward
... Heartland Robotics .... HeartWare International
... Heat
Biologics .... ... HeatGenie ... Helicos
BioSciences
... Helion Energy .... Heliovolt ...
Helius Medical
Technologies ..... Helix
Therapeutics
... Helomics (formerly Precision Therapeutics)
.....
Hemadvance ..... HemaQuest Pharmaceuticals ... Hemarrest ... Hememics
Biotechnologies< .... Hemera
Biosciences .... Hemispherx Biopharma .... HemoGenyx .... Hemoshear
Therapeutics ..... HemoSonics..... Hemostasis
... Hennepin Life Sciences .... Hepion
Pharmaceuticals .... Hepregen ... Heraeus Medical
Components .... Herley Industries
... Hermemics
Biotechnologies .... Hermes Biosciences ... HexaTech
.... Hexfuel .... Hibernaid .... Highbury Defense
Group .... High Impact
Environmental
.... HighPassBio .... High Performance
Technologies ... High Point Pharmaceuticals .....
Histogen
.... HighRes Biosolutions .... Histogenics
... HistoRx
... HistoSonics .... HJM
Precision .....
HocusLocus ..... Hoku
Scientific
... Holaira .... Hollingsworth & Vose .... Hollis-Eden
Pharmaceuticals ... Holomni .... Holos .... Homology
Medicine
.....
Honeycomb Batteries .... Hontek
... Hookipa Pharma .... Hoopers Island
Oyster Aquaculture ...
Hoppe Tool
.... Hoth Therapeutics ..... Howe Industries .... Hsiri
Therapeutics ..... HTG
Molecular ..... HTSS
...
Humacyte
...
Humanetics ..... Human
Genome
Sciences ...
Human
Metabolome Technologies .... HuTerra .... Huya Bioscience International
.... Hybritech ..... Hybrivet .... HYCOR
Biomedical ...
Hydra Biosciences ...
HydroCision ... Hydrogen
Safety ... HydroLogic Industries .... Hygeia
Therapeutics
... HyperBranch Medical
Technologies ... Hyperion Therapeutics ... HyperMed
... HYPRES .. Hy-SyEnce
... HyTrust
i20 Therapeutics .... IAP ... IBC Advanced
.... iBiquity Digital ..... Ibis
....
Iblogix
.... IBT
Laboratories
... Icagen .... Icardiac.... Ichor Medical Systems .... Iconic
Therapeutics ..... Icos.... Icosavax ... ICX....
Idaho.... Ideal
Converters ... Ideapaint.... Ideaya Biosciences ..... Idera
Pharmaceuticals ..... ID Genomics ....
Idevices
... IDx ..... iFirst Medical Technologies ...... IFM
Therapeutics
..... Igenica
Biotherapeutics .... IGM Biosciences ..... Ignyta.... Ii-IV
.... Ikaria... Ikonisys... Illinois Superconductor.... Illumigen....
Illumina.... Illuminating Diagnostics ..... Illuminoss....
Illumitex.... Imagen Energy .... Imagevision.... Imaging
Biometrics... Imagineoptix ... Imago Instruments... Imanis
Life... Imara .... Imbed Biosciences... Imetalx... Immco...
Immersion... Immtech...
Immucell .... Immucor .... Immunai .... Immune...
... Immune... Immune Pharma .... Immunetics...
Immunex...
Immunexcite...
Immuneworks... Immunexpress ..... Immunic ..... Immunicon... Immunitas
Therapeutics ..... ImmunoCellular Thera .... ImmunoChemistry
Technologies ..... Immunocore...
Immunogen... Immunome ..... Immunomedics..... ImmunoMolecular
Therapeutics .... Immunomic Therapeutics
.....
Immunophotonics ... Immurx... .... Immusant...
Immusoft ..... Impact Biomedicines .... Impact Proteomics
.... Impact Science...
Impel
Neuropharma... Imperium Renewables... Impinj... Implant
Sciences... Impossible Foods .... Imprimis Pharmaceuticals .... Imprint
Energy .... Impulse
Monitoring ... Imricor Medical Systems ..... Imris .....
Imthera...
I-nalysis ... Inari Agriculture .... InCarda Therapeutics ....
INCELL .... Incelldx
..... Incitor (now XF
Technologies) .... Incodema3D ..... Incontrol
Research... InCube Labs ..... Incyte ....Incytu... Indalo
Therapeutics ..... Indiana
Nanotech... Indi Molecular ... Industrial Heat ..... Industrial
Perception...
Inentec ... InfaCare Pharmaceutical .... Infarct Reduction
Technologies .... Infinera...
... Infinia... Infinite Electronics .... Infinity... Infinium
.... Inflammatix .... Inform
Genomics... Infoscitex... Inframat... Infraredx... Infrascan... Inf
Robotics ... Infusion Medical ... Ingeneus... Ingeneron .....
Inhibitex... Inhibkase
Therapeutics .... Inhibrx< .... INI
Power... Inland Labs ..... Inmobly .... INmune Bio .... InnAVasc
Medical ....
Inneroptic...
Innerpulse... Innocrin Pharmaceuticals ..... Innography...
... Innopad... Innotec ..... Innovalight...
Innovari Energy Design Microplate Scientific...
pulmonary solutions.... silicon... Innovate Biopharmaceuticals .....
Innovative Spinal...
Innovative... Innoventiontech ... Innovention (now
Ccardiorobotics) ... Innovative Trauma or...
Innovolt ...
Innowave... ... ... Innoviva ...
Innov-x... Inocucor ..... Inorganic Specialists... Inotek...
Ino
.... Inova
Labs
Biomedical... Inovio... Inovise Medical ..... Inozyme Pharmaceuticals
..... Inphase...
... Inphi... Inpria ..... Inscripta ..... Insert MRI...
Insight...
..Insite Vision...... Insitu... InSitu
Biologics ..... Insmed... Inspired Solar Systems ...
Inspire...
Insulet
Labs
... Intact Vascular... Intaglio... Intalio ... Intarcia
Therapeutics ...
Integenx... Integra Group Diagnostics... Integral Molecular .....
Integrated BioTherapeutics
.... Integrated
Diagnostics .... Integrated
Diagnostics InDi .... Integrated DNA Technologies ..... Integrated
Fuel...
... Integration Associates... Intelect
Medical
Intelleflex ... Intellia Therapeutics .....
Intellicyt
Automation Bio-systems ...
Intelligent Devices .... Intelligent Epitaxy Technology .....
Intellimedix ..... Intelliphage.... Intellirad
Control...
.Intellisense .... Intelomed ....Inter-4... Interactive Supercomputing
... Interdigital
Interlace ....
Intermagnetics General ...Intermolecular ... Intermune....
International Stem Cell ... Interpace
Biosciences ..... Interrad Medical ..... IntersectENT ....
Intersense... Intersystems ...
Intervalve.... InterVene .... Intevac.... Intra-Cellular Therapies
.....
Intralase ...... Intralytix .... Intrepida Bio .... Intrexon .....
Intrinsic Therapeutics
.... Intrinsity....
Introgen....
... Intuitive Biosciences .... Intuitive Genomics ..... Intuitive
Surgical.... Invenra ....
Invensense .... Inventev ..... Inverness
Innovations.... Invirsa ..... Invertix.... Invictus.... Inview
Technology....
Inviragen.... Invisage Technologies ....
....InvisionHeart .... Invision Medical ....
Invitae....
Invitrogen.... ...Invivosciences.... Invivo Therapeutics=
Holdings .... Invuity....
Inx Medical.... IoGyn .... Iomai.... ... Iomed....
IOmet
Pharma ..... Ion America Optics..... Ionic Materials ..... IonQ ....
Ion
Torrent.... Iovance Biotherapeutics ..... Iovation.... Iowa Thin
Film....
Ipierian.... IPG Photonics.... ... Iquum
...Irhythm...
iRobot... Iroko...Ironbridge.... ... Ironwood....
... .... Irvine Sensors... .... biopolymer
. .... Ischemia Care.... iSee ..... iSIGHT
Partners
.....
Isis.... Island Ddata....
Isogenis.... Isomark.... IsoPlexis .... Isoray....
Isothermal....
Isthmus Biosciences ..... IstoTechnologies....
itaconix....
I-Therapeutix..... Itherxm Pharmaceuticals.... Itraumacare... .. Itseez
..... Itzbig ..... Iveric bio .... Iwalk
Jade Therapeutics ..... J&Y ... Janssen Biotech .... Janus Biotherapuetics ... Javelin Pharmaceuticals ... Javelin Semiconductor ... JDP Therapeutics ..... Jennerex ... Jnana Therapeutics ..... Joule Biotechnologies .... Jounce Therapeutics .... Joyent .... Joylux .... Joyn Bio .... Juno Therapeutics ..... Just Biotherapeutics
K2M .... K2 Therapeutics
.... KAER
Biotherapeutics .... Kala
Pharmaceuticals ... Kaleido Biosciences .....
Kallyope ..... KaloBios Pharmaceuticals ..... Kalocyte .... Kalon
Biotherapeutics ..... KalVista Pharmaceuticals .... Karius ..... Karuna
Therapeutics ...
Karyopharm Therapeutics ... Kateeva
..... Kayo
Technology ..... KaZaK
... KC BioMediX ... KCI .... KDH Defense Systems
... Kebotix .... Keithley Instrument ...
Kelyniam ...
Kenall
Manufacturing
..... Kensey-Nash
... Kent Displays ... Kentucky
BioProcessing ....
KeraNetics .... Keros Therapeutics ..... Kezar Life Sciences ..... KeyW
.... Kilawatt
Technologies ... Kindara .... KinDex ... KindHeart ..... KineMed ....
Kinestral Technologies ..... Kineta ...
Kinetic
Concepts .... Kinex
Pharmaceuticals .... Kingbright .... Kior .....
Kips Bay
Medical ... Kite Pharma ..... Kitware ...
Kiva Systems ... KLD
Energy Technologies .... Klotho Therapeutics .... KMel
Robotics .... Knightscope
.....
Knome ...
Knopp
Neurosciences .... KNOW Bio ..... Know Labs .... KnuEdge ....
Koam
Engineering Systems .... Kodiak Sciences
.... Kolltan
Pharmaceuticals
...
Komoku ... Kona Medical .... Konarka ... Koning ...
Kopin
.. KOR
Electronics ...
Koronis Pharmaceuticals ... Kosan Biosciences ... Kosmetikos
....
Kovio ... KPI
Therapeutics (from Kineta)... Kraig Biocraft ..... Kratos Defense
& Security
Solutions
.... Kronos Advanced
Technologies ... Krystal Biotech .... KSE
... KSQ Therapeutics ..... Kultevat ..... Kura Oncology ....
Kumu Networks .... KVH
.. Kylin
Therapeutics
...
Kyma ....Kymera Therapeutics ..... Kymeta
... Kyn Therapeutics .... Kyocera
Solar .... Kypha ..... Kyras Therapeutics ..... Kyron Clinical Imaging
.... Kytopen
LAAMScience
... LaBelle
Associates .....
LabNow
...Laborie Medical Technologies ... Labrys Biologics ... Lacerta
Therapeutics ..... Lactic
Solutions ..... Laguna
Pharmaceuticals (formerly ChanRx) ..... La Jolla
Pharmaceutical
... Lake Shore Cryotronics .... Landec
.... Landos Biopharma .... Lantern
Pharma ..... Lantheus
...
Lantos
Technologies ... Lariat Biosciences .... Laser
Design .... Lasergen ..... LaserMax ..... LaserMotive
... Laser Tissue
Welding .... Lattice Biologics ..... Lattice
Biotech .... LaunchPad Medical .... Lawrie ... Lazarus Effect
..... LDR
Holding
..... Leading Edge Crystal Technologies ..... Lead Therapeutics
... LeafBio .... LeCroy ... LED Lighting
Fixtures
... Lehigh
Technologies .... Leica Microsystems
.....
LetoSolutions .... Lexicon
Genetics
... LexaGene ..... Lexicon Pharmaceuticals ... Leuko .... Leyden Energy
...
Libra
BioSciences .... LifeCell ... LifeGen
Technologies ...
Life Image ... LifeMine Therapeutics .... LifeSprout ....
Life Technologies
....
Ligand
Pharmaceuticals ....Ligon Discovery ... Lightpointe
... Light Sciences Oncology ... LightWorks Optics
....
Lilliputian Systems
.... Lily Robotics ..... Linares Management
Associates
.. Lingotek
... Linnaeus Therapeutics .... LinQuest .... Lionano .... Lion
Biotechnologies ..... Lipocine ....
LipoScience
...
Liquid Biotech ..... Liquidia
Technologies ...
Liquid Light ...
Liquid Metal
Battery ...
LiquidPiston ... Liquid Robotics ... Liquid X Printed Metals
....
LiQuifix ...
Lithium Technology
... LiveData ... . LiveLeaf
Bioscience .... LKC Technologies ... Locana.... Locus Biosciences ....
Lodo
Therapeutics .... Logical
Therapeutics
... LogicBio Therapeutics ..... Logos
Tech
... Lohocla Research
.....
Lombard Medical ..... Longeveron ..... Longeviti .... LonoCloud .....
Lookingglass ..... Loon Medical
..... Lotus Tissue
Repair
...
Loxo Oncology ... LPath Thera .... Lq3 Pharmaceuticals ....
LS9
...
Luca
Technologies .... Lucerno Dynamics .... Lucidux ...
Lucigen
.... LumaSense Technologies .... Lumena
Pharmaceuticals .... Lumen Bioscience .... Lumencor
... Lumense .... Lumera ... Lumicell Diagnostics
... Luminar Technologies ..... Luminary Micro ...
Luminex .... Luminus Devices ... Lumisyn
..... Lumitex
... LumiThera .... Lumos Pharma .... Luna Innovations
... Luna Technologies
... Lung Therapeutics .... Lutonix
... Luxtera
... Lycera ... LyGenesis ..... Lyncean ..... Lyndra
Therapeutic ... Lynntech ... Lynx Biosciences ... Lyra Therapeutics
..... Lysosomal Therapeutics ....
Lytro Therapeutics
M3 Biotechnology ....
MabVax .... MacAulay-Brown
..... Macrochem ...
MacroFab ..... Macrogenics
... Macrolide Pharma ..... Macrophage Therapeutics ....
Madison
Vaccines .... Madrigal Pharmaceuticals ..... MagBioSense ..... Magenta
Therapeutics ..... Magic Leap
..... MagneMotion ...
Magnesium Development ..... Magnetek ... Magnolia
Medical
Technologies .... Magnolia Optical
Technologies
... Magnolia Solar ... Mainstay Medical International ......
Mainstream Engineering ... Major
Pharmaceuticals .... Mako Surgical
... Manhattan Scientifics ..... Mantra Bio .....
>Manufcturing Techniques ..... MapInfo
...MAP
Pharmaceuticals
... Mapp
Biopharmaceuticals .... Marathon Pharmaceuticals ..... Marcadia
Biotech
... Marina Biotech ... Marinus
Pharmaceuticals
... Maritime Applied Physics ....Marker Therapeutics ....
Marrone Bio Innovations
....
Martek Biosciences ...
Mascoma ... Mashery
... Mason Box ... Masten Space Systems
... Masterson Industries .... Mast Therapeutics
(formerly
ADVENTRX) .... Material Sciences ... Material
Technologies ... MathStar ... Mati
Therapeutics .... Matouk
Textiles ... Matritech ... Matrix Product Development
.....Matrix
Research ....
Matrix Sensors ... Maverick Therapeutics .... MAX
BioPharma
...
MaxCyte ...... Maxdem
... Maxpower ... Maxygen ....
Maze Therapeutics .... MBio Diagnostics
.... MC10 .... MCube .... M
Cubed Technologies .... MD Biosciences ..... MDSolarSciences
... Mebias Discovery ..... Mechanical
Technology
...
Mechanology ... Medafor ...
Medarex ...
MediBeacon .... Medicago USA .... Medical21 ..... Medical Cyberworlds
.... Medical
Device Logistics ...
MedicaMetrix... Medgenics ..... MediciNova .....
Medicool
Technologies .... MedImmune ..
Medina Medical .... Mediomics .... Medior Therapeutics .... Medis
... MEDITE Group .... Medivation ... Mednology Solutions ....
Medrobotics ...
MedShape .... MedSocket (formerly 1CDS) ...... Medsphere Systems .....
MedTel ..... MEI Pharma
..... Meka .... MELA
Sciences .... Melinta Therapeutics .... Melior Discovery .... Memjet
...Memry ...
Memsic ... MEMS Optical... Mendel Health .... Menlo Therapeutics .....
MER
...
Mercator Therapeutics ... Mercury Computer
Systems .... Merganser Biotech ....
Merge
Technologies ... MeriaGTx ..... Meridian Bioscience
... Meritage Pharma ..... Merkatum ... Merrimack
Pharmaceuticals
... Meryx .... Mersana Therapeutics ... Mesa
Photonics ... Mesocopic
Devices ... Metabasis ... Metabiota .... Metabolic Solutions
Development .... Metabolex .... Metabolix
... MetaCarta ... Metacrine .... Metactive Medical
.....
Metal Oxygen
Separation Technologies ... Metamark Genetics ...
MetaModix
... Metavention ..... Metompkin Seafood .... MetroLaser ...
MGC
Diagnostics
...
MIACH Orthopaedics ..... Misaole .... Micell
Technologies
... Michelman ... Micracor .... Micrel ... Microbiotix ....
MicroCoating ...
Microbe Detectives
... Microbia ... Microbot Medical ... Microfluidics International
(Microbia)
... MicroGreen
Polymers .... MicroIslet ...
Microlin Bio ....
MicroMask ...
Micronics ... MicroOptical (New
Mexico)... MicroOptical
(Massachusetts) ... MicroOptx ..... MicroPower Technologies
...
MICROrganic Technologies .... MicrowSat
Systems .... Microscopy Innovations ..... Microstaq
... MicroTransponder ..... Microvision ... MicuRx
Pharmaceuticals
.... Midori Renewables
..... Mid Valley
Industries
... Milestone Pharma ..... Millendo
Therapeutics (born as
Attercor) ..... Million Concepts ..... Miltec .... MiMedx Group ....
MimiVax ....
Minerva
Biotechnologies
... Minerva Neurosciences .... Minerva Surgical
.... Minimally Invasive Devices .... Minnesota
Thermal Science ..... Minnetronix ... MIOX ..... Mirador Biomedical
... Mira Dx ... MiRagen
Therapeutics .....
Miramar Labs .... Mirati Therapeutics ..... miRecule .... Mirimus ...
Mirina ... Mirna
Therapeutics.... Miromatrix Medical ...
Mirus Bio ....Mirum Pharmaceuticals ..... Mission Bio ..... Mission
Research ...
Mississippi Polymer ... Mithridion ...
Mitochon Pharmaceuticals ..... Mnemosyne
Pharmaceuticals ...
Mobile Robots ... Mobius Therapeutics ..... Moderna Therapeutics ....
Modern Meadow .... Modern Technology Solutions
.... Modis Therapeutics ..... Moduline Systems .... Modumetal .....
MOgene Green Chemicals ....
Molecular
Biometrics
... Mohawk
Innovative Technology ..... Molecular Assemblies .... Molecular
Detection ... Molecular Diagnostics .... Molecular Imprints
... Molecular Insight
Pharmaceuticals ... MolecularMD ... Molecular
Sensing ... Molecular Templates
.... Moleculin Biotech ..... Molten
Metal .. >Moma Therapeutics ..... MoMelan
Technologies ... Momenta
Pharmaceuticals ... Monebo ... Monogram Biosciences
.... Monopar Therapeutics ..... Monteris Medical
..... Morphic Therapeutics
.....
Morphormics
... Morphotek
...
Morris
Innovative Research ... Mortara Instrument ...
MortaSecurity .... Motif ... Motricity
... Motus Therapeutics .... Mound Laser
& Photonics Center ..... Movia Robotics ..... Moximed ....
mPower Technology .... MPP
Group ... MPSP ...
MSNW ....
Mudawar Thermal
Systems
.....
Munksjo Paper ... Muons ... Muse bio .... Myco
Technology
....
Myocor
... MyoKardia
...
Myomo
... Myonexus Therapeutic ..... Myovant Sciences
.....
Myriad Genetics
...
Myriant
Technologies
... Mystic Pharmaceuticals
N12 Technologies
... (N30 Pharmaceuticals) now Nivalis Thera .... NABsys
... Nalas
Engineering ....
Nammi Therapeutics ..... NanOasis Technologies
... NanoBio
...
Nanobiosym ... Nano-C ... NanoCellect (formerly NanoSort)
.....
Nanocomp Technologies ...
NanoCoolers ... Nanocopoeia ... NanoCor Therapeutics
...Nanodynamics (Buffalo) ... Nano DX ..... Nanodynamics
(NYC)...
NanoeXa
.... Nanofiber Solutions ... Nanogen ... NanoGraf (formery SiNode)
..... NanoGram .... nanoGriptech
..... NanoGuard Technologies .... NanoH2O ...
Nanohmics ... NanoLab
... NanoLite Systems ... NanoLogix ...
NanoLumens
..... Nanomaterials
Research
... NanoMatrix ... NanoMedex ... NanoMedicalSystems
...
NanoMedical Systems .. Nanomix ... nanoMR ..... Nanophase
Technologies
... NanoPhotonica ... Nanopore Diagnostics ..... Nanoptek
... Nanoramic
Laboratories (formerly FastCap Systems) ..... nanoRETE .... Nanoscale
Components ...
Nanoscale
Materials
... Nanosolar ...
Nanosonic ... Nanospectra Biosciences .... Nanosphere ... NanoSteel
...
Nanostim .... NanoString
Technologies .... Nanosys ...
NanoSystems ... Nano Tailor ... Nanotek Instruments
.....
Nano-Terra ... Nanotherapeutics ..... NanoTune Technologies
... Nanova
....
Nanovation
Technologies ... NanoVault Medical .... NanoVibronix ... NanoViricides
... NanoVision Diagnostics .... NantCell
..... Nantero .... NantHealth ... NantKwest ..... Napo
Pharmaceuticals ... Narus
Biotechnologies ..... Nascentric
... Nastech
Pharmaceutical ... Natera .... National Technical Systems
..... Natural Molecular Testing ..... NaturalNano ...
Nature's
First .....
Natus Medical ... Naverus ... Navidea
Biopharmaceuticals ... Navini Networks
... Navire Pharmaceuticals .... Navitor Pharmaceuticals ....
Navmar Applied Sciences
... NBD Nanotechnologies ....NCD Technologies
.... nContact
Surgical ...
Neah Power ... Near Infinity .... Neato Robotics ... Necci
.... Nektar
Therapeutics ... Nekton
Research
.... NemaMetrix .... NeoChord ... Neogen
.... NeoGenomics ..... Neograft
..... Neoleukin Therapeutics ..... NeoLight .....
Neon Therapeutics ....
NeoPhotonics ... Neoprobe
...
Neos Therapeutics ..... NeoSync ..... Neothetics .... Neotron
...
NephroGenex .... Nereus
Pharmaceuticals ... Nest .... Netcentric .... Netezza ...
NetLogics
Microsystems... Netspeed Systems ...... Net Watch
Solutions
..... NetworkFab
...
NeurAccel
Biosciences ...
Neurala .... Neural Analytics .... Neuralstem .... Neuraly
..... Neuraptive
Therapeutics .....
Neuro
Amp .... Neurobiological
Technologies
...
NeuroChaos Solutions .... Neurocrine Biosciences
...
NeuroDx Development ... NeuroEM .... Neurodyne Medical ...
Neurofluidics ....Neurogastrx .... Neurogen
... NeurogesX ...
Neurognostics .. NeuroHabilitation .... NeuroLogica
.... NeuroLutions ..... NeuroMap
... Neuro Kinetics ....
NeuroMetrix... Neurona Therapeutics .... Neuronetics .
Neuronex .. NeuroOne ..... NeuroPace
...
NeuroPhage
Pharmaceuticals
... Neuron Systems ... NeuroPointDX
..... Neuroptix
... NeuroRecovery
Technologies .... Neuroscience .... NeuroSigma .... NeuroTek ....
Neurotrack ....
NeuroTronik .... Neurotrope ..... Neurovance
... NeuroVigil ...
Neurovascular
Diagnostics ..... NeuroVision Imaging .... NeuroVista ....
NeuroVive
.... NeuWave
Medical ...Nevro ... New Dominion Enterprises ..... NewLeaf
Symbiotics .... NewLink Genetics
.... Newlink genetics england ... biolabs ...
new
era technology ... New Haven Pharmaceuticals ... Nexant
...Nexbio
... NexImmune .... NexPlanar .... NextCODE Health ....
NextCure ..... Nextio ....
NEXTracker
....Nextreme Thermal Solutions ... NextStep Robotics .....
Nexus
Biosystems ..... NG1 Technologies .... NGM Biopharmaceuticals .... Nico
..... Night Vision ... Nido Biosciences ....
Nimblegen Systems ... Nimble Storage .... Nimble Therapeutics
.... Nimbus Discovery ... Nimbus
Therapeutic
.....
Ninepoint
...Niowave ... NIRvana Sciences .... Nitero....
Nitric Biotherapeutics
....Nitricgen ... Nitride Solutions .... Nitrogenics ..... Nitrome
Biosciences ..... Nitromed ...Nitronex
... Nivalis Therapeutics formerly N30 Thera ..... NKT
Therapeutics ...
Nlight ... NMT Medical .... Noah
Technologies ....
Noble Fiber
... Nocion Therapeutics .... Nohla Therapeutics
.... Noivatone .... Nok Nok
Labs .... Nomadics .... NONA Composites .... Noninvasix ....
Nonvolatile
Electronics .... Nora Therapeutics .... Norian ... NorMedix
.....
Normoxys
.... Norse .... Northeast Photosciences
... Northstar Medical
Radioisotopes .... Northstar Photonics...
Northwest Biotherapeutics .. Norwich Technologies ....
Nostopharma .... Notice
Ttechnologies ... .Novacea
... Novalar Pharmaceuticals ... Novalux
... Novan
Therapeutics .... NovaScan
... Nova Synthetix .... Novatek ... NovaTorque
... NovaTract
Surgical
... Novavax .... Novazyme Pharmaceuticals ..... Novecon
Technologies ... Novella
Clinical
.... Novelos
Pharmaceuticals
... Novelos Therapeutics ... Noveome Biotherapeutic
.....
Novian Health .... Novira
Therapeutics ...
Novocell ... Novogy
... Novome Biotechnologies .... Novomer
...
Novophage ... Novo Sol-u-tions MD .... Novosource ...
Novozymes .... Novus Biologicals ....
Noxilizer
... Nox Technologies ... NP Photonics ...
NPS Pharma ..... NRGindependence ..... NSS Labs
..... Nucelis
.... Nuclea
Bioechnologies ... Nufern .... NuGEN Technologies ..... NuMat
Technologies ..... NuMedii
.... NumereX .... NUMiX Materials ..... NuPathe .... Nurel
(now PeriphaGen) .... Nurix Therapeutics ... Nuron
Biotech ... Nutrabiotix
... Nutrient Recovery and Upcycling .... NuVant
... Nuvaira .... NuVascular Technologies ....Nuvation Bio ....
Nuve .....
Nuventix ...
Nuvera Biosciences ... Nuvera Fuel Cells.. . Nuvotronics
.....
Nuvox
Pharma ..... Nu Waves ..... NxThera ... Nvision
Biomedical
Technologies ..... NZ
Applied Technologies
Oak-Mitsui .... Oasys
...
ObjectVideo
... Obsidian Therapeutics ..... OBS
Medical ... Ocarina Networks ... Ocata Thera ...
Occipital .... Ocean Bio-Chem .... Ocean Power
Technologies
... Ocean Renewable Power .... Ocera Thera .... OCI ...
Ocugen ..... Ocular
Therapeutix
....
Oculeve
... Oculogica ..... Oculus ... Oddpost
... Odyssey Systems
Consulting Group ... Oil Chem
Technologies ... OLEDWorks .... Omeros
... OmniGene Bioproducts ... OmniGuide ...
OmniLytics
... Omniox ..... OmniSonics Medical Technologies
... Omnis
PharmaRebiotix .... Omni
Water Solutions ... Onboard Dynamics .... ONCE Innovations
.....
OnChip
Power .... Oncobiologics ..... OncoCyte
.... Oncogenex
... Oncolmmune ..... Oncolinx .... Oncolix ..... Oncolytics
Biotech
...
OncoMed
Pharmaceuticals .... OncoNano Medicine .... Onconova
Therapeutics
...Oncoscope
...
OnCore Biopharma ..... OncoResponse ..... Oncorus .....
OncoSec
Medical
.... OncoTartis ...... Oncothyreon
... Oncovista Innovative Therapies ..... Oncternal
Therapeutics ... Onduo ..... One
Resonance Sensors .... Onexio Biosystems .... Onko Solutions ....
OnKure Therapeutics ..... ONL
Therapeutics .... OnLume ....
On-Q-ity .... Onspira Therapeutics .... On Target
Laboratories
.... Ontela ..... On-X
Life
Technologies ....
Onyx
Pharmaceuticals ... Oorja
Protonics .... Open Algae ... Open Monoclonal Technology
.....
Open Silicon
... OpenWater
Power .... Opertech Bio ..... Opexa
Therapeutics
... OpGen ... OPNET Technologies
... Opsonix .... OptTek
Systems ... Optelecom ...Optelecom-NKF ... Optherion ...
Optical
Concepts .. Optigain .. Optimal Technologies ... Optimus
Technologies .... OptiNose .... Optivision
...
Optofluidics ... OptoLum ..... Optonicus .... Opto Technology
...
Optomec
....
OPX
Biotech
... Oragenics .... OraMerix
... Orasi Medical ... OraSure
Technologies .... Orbital Insight .... Orbital Sidekick ... Orbital
Technologies
... Orbotix .... Orchard Therapeutics .....
Orchestra BioMed .... Orchid
Cellmark
... Oregon Iron
Works .... Orexigen
Therapeutics
... Organic Research .... Organogenesis ...
Organovo
..
ORIC Pharmaceuticals ..... Oricula Therapeutics .... Origin
Medsystems ..... OriginOil
... Orion Energy Systems ... Orion Genomics ...
Ormet
Circuits ... Oroboros Bio .... Orologic...
OrphoMed ..... Ortel ...
OrthoAccel
Technologies ... Ortho Kinematics
.... Oryx Technology ... Osazda Energy ... Oscient
Pharamceuticals ...Oscilla
Power
.... Osiris
Therapeutics ... OSI Pharmaceuticals ... Oso Biopharmaceuticals
Manufacturing .... Osprey Medical ....
Ossianix
... OSSIO ..... Ostendo Technologies ...
Osteotech ... Osterhout Design Group .... OtoNexus Medical
Technologies .... Otonomy .... OtoSense
.... Ottomatika .... Outset Medical .... OvaScience ...
>Ovid Therapeutics ..... Oxalo Therapeutics .... Oxford
Performance Materials ... Oxis International .... Oxygen
Biotherapeutics ... Oyster Point Pharma
P3I ... Pace Packaging
.... Pacific Biosciences
.... Padlock Therapeutics .... Pain Therapeutics ...
PaizaBio .... Palvella Therapeutics ... Palantir Technologies ....
Palleon Pharmaceuticals ....
Palmaz Scientific ..... Palmer
Labs
...
Paloma Pharmaceuticals ... Panacea Solutions ....
Panacos
... Pandion ..... Pandromics ..... Pan Genome Systems .... Panomics
..... PanTheryx .... Paper
Battery ....
PapGene .... Parabricks .... Paradigm Diagnostics
.... Paradigm Sensors
... Paradromics ..... ParaGen Technologies ..... Paragon
Bioservices ..... Paragon Dynamics .... Paragon Space
Development ...
Paragonix Technologies .... Parasol Therapeutics
... Paratek
Pharmaceuticals .... Parexel International .... Parhelion .... Parion
Sciences
... ParkerVision .... Partner Therapeutics ..... Partpic ....
Passage Bio ... Passport
Systems ... Pasteuria Bioscience ... Pathfinder ...
PathoGenetix
... PathoVax ..... Pathway Genomics .... PatientStream ...
PatientWise ...
Patton Medical Devices ... Patton Surgical .... Pavilion
Technologies ... Pax Streamline ... PaxVax ...
PDI Therapeutics ..... PDL
BioPharma ... PDS Biotechnology ..... Pearl
Therapeutics
... Pear Therapeutics ..... PECA Labs
.... Pediatric Bioscience .... Peerless Technologies .... Pegasus
Sustainability Solutions ....
Pelican
Products ..... PellePharm .... Pellion
Tech ... Peloton Therapeutics ..... Peninsula
Pharmaceuticals ..... PennAlt Organics ..... Penumbra .....
PeproMene Bio .... Peptimed
... Peptilogics .... Peptimmune
... Perceptive Navigation ..... Perceptive Sciences
... Perceptron ....
PercipEnz
Technologies
... Peregrine Semiconductor .... PeriphaGen .... Permeon
Biologics
...
Perosphere .... Perscitus Biosciences ... Perseon .....
Persimmon
Technologies ....
PersonalBee ... Personalis ...... Personal Genome
Diagnostics
.... Pervasis Therapeutics
... Pervasive
.... Petra Pharma ..... Pfenex ...
Pharmacyclics
.... PharmaJet .... PharmAkea Therapeutics ....
Pharmasset
... PharmAthene
... PharmatrophiX .... PhaseBio
Pharmaceuticals .... Phase Bioscience ... PhaseRx ....
Phigenix
..... Phoenix (formerly Phoenix Nuclear Labs) ..... Phoenix Analysis
and Design Technologies ..... Phoenix
Biotechnology .... Phoenix Molecular Designs .... Phoenix
Nuclear Labs ...
Phio Pharmaceuticals .... Phoenix Science
.. Phononic
Devices
... Photobit ... Photolitec .....
PhotoMedex
... Photonics
Innovations ... Photon-X ....
PhotoSonix Medical .... PhotoThera
...
Photronics ... Phoundry Pharmaceuticals .... Phraxis
.... Phrixus
Pharmaceuticals ..... Phurnace
Software ... PhylloTech ..... Phylonix
.... Phylos Bioscience ..... Physcient .... Physical
Optics... Physical
Sciences
... PhysioGenix
... PhysioSonics ... PhytoTech ... Picolight ....
Picometrix
... PIC Therapeutics .... Piedmont Biofuels .... Pieris
Pharmaceuticals ..... Pika
Energy ... Pilus
Energy ....
Pinger
...
Pinnacle Technology ... Pioneer Surgical
Technology .... Pionyr Immunotherapeutics ..... Pivot
Bio ..... Pixelligent .... Pixel
Optics .. Pixim ... Pixtronix ... Plakous Therapeutics .....
Planar Energy
...
Planar Systems ... Planet Labs .... Plano Microwave ..... Plasan ...
PlasmaTech Biopharmaceuticals .... Platelet
BioGenesis .... Platypus
... Play-i
.... PLC
Medical Systems
... Plextronics ... Plexxikon
... Pliant Therapeutics .... Plug
Power ... Pluromed ... Plus Therapeutics .... PLx Pharma
..... PLX Technology ....
PMT
.... PMV Pharmaceuticals .... PneumRx .....
Point Source .... Polarean ..... Polatis
.... Polychromix
...
Polyera ... PolyMedica ... PolyMedix ... Polymer
Technology
Systems ... Polynoma ..... PolyNova .... PolyPlus ... PolyRemedy ...
Polysciences ... Polystor ... Portola
Pharmaceuticals ... Poseida Therapeutics .... Possis
Medical ... Pothole Pros ... PowerGenix ...
Powerlight
... Power
Precise Solutions ... PowerVision ... Pozen ... PQ
Bypass .... Prairie
Technologies ..... Pranalytica ... Praxis Biotechnology .....
Precipio ... Precision Biopsy
... Precision BioSciences
.... Precision for Medicine .... Precision Genome
Engineering .... Precision Ocular Metrology ..... Precision Optics
...
Precision
Therapeutics (now Helomics) .... Precision Virologics .... Precisive
Surgical .... Predictive
Biosciences
... Pregmama ..... Prellis Biologics .... Presage
Biosciences
... Presidio
Pharmaceuticals
.... Pressure BioSciences
... PreTalen ..... Prevail Therapeutics ..... Preventice .....
Prevention
Pharmaceuticals ....
Prieto Battery ..... Primary Data ..... Primera
Biosciences ... Primordial .... Primorigen Biosciences
... Primus Power .... Princeton Satellite
Systems ..... Principia Biopharma ....
Prism
Solar Technologies .... Procept BioRobotics ..... ProCertus
BioPharm
... Processa Pharmaceuticals .....
Proclara
Biosciences (formerly
NeuroPhage
Pharmaceuticals) .... Procyrion .... Profectus BioSciences .
.. Progenics
Pharmaceuticals
... Progenity .... Progeny Systems ..... Prologic
...
Promedior
...
Promega ..... Promentis .... Prometheus Laboratories
.... PROMISS
Diagnostics ...... Pronutria ..... Propagenix ..... Propeller
Health .... Propulsive Wing .... ProstaGene ....
Protagonist
Therapeutics .... Protein Foundry ..... Protein Sciences
... ProteinSimple (formerly Cell
Biosciences) .... Proteon Therapeutics
...
Proteostasis
Therapeutics
... Proteotech ... Proteus
Biomedical
... Proteus Digital Health .... Protez Pharmaceuticals
.... Prothena .... ProThera Biologics ...
Proto Labs ... Proton Energy Systems ...Protonex ..
Prototype
Productions .Provagen ... Provenance Biopharmaceuticals
... Provention Bio .... Proventys
... Provista Diagnostics .... Pryor Medical Devices .....
PsiKick
..... pSivida
... PTC Therapeutics
.... Pulmatrix ... Pulmonx .... Pulmotect ..... Pulse
Aerospace .... Pulse
Electronics ....
PulseTherapeutics .... Puma Biotechnology ..... PUR
Biologics ..... Pure Bioscience .... Purfresh
... Purillume ..... Pursuit Vascular ... PurThread
.... PvP
Biologics ..... Pylum Biosciences ... Pyran ... Pyxis Oncology
Qcept Technologies ....
Qcue .... QD Vision
... QED ... qFuzion ..... Qioptiq
... QM Power
... Qpex .... QPixel ... QR
Pharma
... QSpex .... Qteros
... QuaDPharma .... Quadra-Aerrow International ...
Quadraspec
...
Quad Technologies .... Qualcomm ... QualityMetric
...
Qualtech Systems ....
Qualtré ... Quanterix
... QuantRx Biomedical
.... Quanttus .... QuantTera .... Quantum Circuits ..... Quantum
Epitaxial
Designs ... Quantum Fuel Systems... Quantum Logic
Devices
... Quantum Materials .... QuantumSphere
.... Quantum Xchange .... Quark
Biotech ... Quark
Pharmaceuticals ... Qubitekk ..... QQuench Bio .... Quentis
Therapeutics .....
Quick–Med
Technologies .... Quid ..... Quidel
... Quincy
Bioscience
... Quintessence Biosciences ... Quorum
Systems QurAlis
Radant Technologies ... Radiabeam Technologies
... Radiance Technologies .... Radiant Photonics...Radiation
Monitoring Devices
... RadioMedix ... Radius
Health ....
Rafagen ... Rainbow Organic Farms ... RainDance
Technologies
...
RainStorm ...
Rain Water Solutions ... Rallybio ..... Raland Therapeutics .... RaNA
Therapeutic ...
RAN Biotechnologies .... Range Fuels
... Rapamycin Holdings ..... RaPharmaceuticals
... Rapid Diagnostek ... Rapid
Micro Biosystems
... Rapiscan ... Rapt Therapeutics ... RareCyte
..... Raser Technologies
.... Raydiance ... Raydiant Oximetry .... Raymond
.... Raze
Therapeutics
.... RE2
.... ReadCoor ..... Ready Robotics ..... ReAlta Life
Sciences .... Reata Pharmaceuticals ....
Rebellion
Photonics .... Rebion ..... Rebiotix ....
Receptor Logic ...
Receptos
..... Recodagen ... ReCode
Therapeutics .... Recombinetics
... ReconRobotics
.. Recovery Engineering ..... Recro Pharma ....
Recursion
.... Redox Power
Systems .... Redpin Therapeutics .... Red Rock Biofuels .... RedShift
BioAnalytics .... Redwood Robotics .... RedZone
Robotics .... RefleXion
Medical .... Refuge Biotechnologies .... Regado
Biosciences
... ReGear Life Sciences ..... ReGen
Biologics ... Regenerative
Medical Solutions ..... Regenerative Sciences ... Regentys
(formerly Asana Medical) .... Regenxbio
....
Regulus Therapeutics ... Rehabtics .... Relativity Space ....
Relay Therapeutics
..... ReliantHeart ....
ReliefBand Technologies ..... Relievant Medsystems
..... Relypsa .... Remedy Plan Therapeutics .... Remedium
Technologies ... RemoteReality .... Rempex
Pharmaceuticals .... Renaissance Services ..... Renegade
Materials .... Reneo
Pharmaceuticals ..... Renerva ..... ReNeuroGen .... Renewable
Alternatives
... Renewable Energy Group .... Renmatix .....
Renovacor
..... RenovoDerm ..... Renovia .... Renovion .... Renovis ...
Rentech ... Repare Therapeutics .... Replidyne
...
Repligen .. Replimune Group .... Research Frontiers
.. Research Innovations ..... Resolve
Therapeutics
... Resolvyx
Pharmaceuticals ... Resonetics ..... Respicardia
... Respira
Therapeutics .... Response Genetics
...
Restoration Robotics ..... resTORbio ..... Restore Medical ... Retectix
..... Retek
...Rethink
Robotics ... Retia Medical .... Retriever
Technology
.... Retrophin< ... RetroSense Therapeutics .....
Revacom ... Reva
Medical
... Revance Therapeutics Pharmaceutical ....
Revegen
... ReVision Optics ....
ReVision
Therapeutics .... Revitope Oncology ..... ReVivo Medical
....
RevMedx .... ReVolt Tech
... Revolution
Medicines .... ReWalk
Robotics (Israel) .... Rexahn
Pharmaceuticals
... Rex Computing ..... RF Code ...
RFMicron
.. RFS Pharma ..... RF Surgical.
.... Rgenix .... Rgenta Therapeutics .... Rhenium
Alloys .. Rheos Medicines ..... Rheostat
Therapeutics ..... Rheumco .... Rhevision
... Rho ... Rhythm Pharmaceuticals ... Rhythmia
Medical
... Ribometrix ....
RiboNova .... Ribon Therapeutics ..... Rib-X
Pharmaceuticals ... Rice Technology ..... Ridgeback BioTherapeutics
.... Ridgetop
Group ... Rigel Pharmaceuticals .... RightEye ..... RightHand
Robotics .... Rinat
Pharmaceuticals
.... Rinovum Women’s Health ..... Rio Grande Neurosciences .....
RipCode ... Rite
Solutions .... Ritter
Pharmaceuticals ..... River Vision Development ..... Rive Technology
... RJA Dispersions ... R.L. Phillips ...
RMH
Sciences ...
Robb Surgical Devices .... Robopsy ...
Robotic FX ... Robotics VISION
Technologies ..... Robotic Research .... Robotic Technology
... Rocket Pharmaceuticals .... Rockwell Medical
..... Rocky Research .... Rodeo Therapeutics ..... Rodin
Therapeutics ... Roka
Bioscience
.....
RoosterBio .... RootPath .... Rosina Food Products ....
Ross Valve ..... Rotational
Medical .... RotoMetrics ..... RoverMed Biosciences ..... Rowbot
Systems .... Royole ..... RQx
Pharmaceuticals .... RRE
Solar ....
Rubicon Tech ...
Rubigo Therapeutics .... Rubitection ..... Rubius Therapeutics ....
RubrYc Therapeutics ..... Rules-Based
Medicine
... Rushford Hypersonic ... Ruud Lighting ..... RxFunction
...
RXi Pharmaceuticals
...
RxMedic .... Rypos
S2 ... Sadasis
.... SafeShot .... Saffron
Technology
.... Sage
Electrochromics ... SADAR 3D .... SafeLi .... Sage Science
... Sage
Therapeutics ... Sakti3 ... Salarius
Pharmaceuticals .....
Salient Surgical
Technologies
... Salix
Pharmaceuticals ... Salutaris Medical Devices ..... SAM Medical ....
Sancilio
Pharmaceuticals .... Sand 9 .
.. Sandia Biotech .... Sangamo
Biosciences
... Sangart
... Santalis Pharmaceuticals ..... Santarus .... Sanuwave
Health
.... Sapheon .... Sapphire
Energy ....
SARbarcode .... Sarda
Technologies ...
Sarepta Therapeutics .... SatCon
Technology ...
Satori Pharmaceuticals
.... Savara Pharmaceuticals .... Savi ...
SBH
Sciences ...
Scanadu ..... Scholar Rock .... Sciaderm ..... SciClone
Pharmaceuticals
... Sciencescape ..... Scientific
Conservation .... Scientific Research ...
Scientific
Solutions ... Scientific Systems ... SciFluor Life Sciences ... Scilex
Pharmaceuticals .... Scinovia ..... Scioderm .... Scion Plasma ....
SciQuest ...
Scopic Software
... Scout Bio .... scPharmaceuticals ..... Scynexis ...
SD Catalyst
Group ... SDL .. SeaChange ...
Seacoast Science
... Seahawk Biosystems ... Seahorse
Bioscience
... Seaside Therapeutics .... Seattle BioMed .....
Seattle
Genetics
...
Seattle Medical Tech .... Sebacia .... Second Genome ....
Second
Sight Medical
Products ... Securboration ..... Secure
Computing ... Sedia Biosciences ..... Seeo
....Segetis ... S.E.G-WAY Orthopaedics .... Seldon
Labs ... Selecta Biosciences
... SELLAS Life Sciences Group .... SeLux
Diagnostics .... Sema4
Natalis
..... Semiconductor
Laser ... SemiProbe ... Semler
Scientific
.... Semma Therapeutics .... Semnur
Pharmaceuticals .... Semprius ... Semprus
BioSciences .... Sencera International ...
SenesTech .....
SenGenix ....
Senior Scientific ..... Seno Medical
Instruments .... Senomyx
... SensAble Technologies ... Sense .... Sense
Diagnostics
....
Senseonics ..... Sensintel .... Sensiotec ...
Sensors
Unlimited
... SensorTran ... Sentelligence
... Senti Biosciences ..... Sentient
Technologies ..... SentreHEART ..... Sepracor
... SeprOx .... SeQual Technologies ... Sequella ...
Sequel
Pharmaceuticals .... Sequenom ... Sequenta ...
Sequent
Medical
.... SeraCare Life Sciences ... Seragon
Pharmaceuticals .... Seraxis ..... Seres Therapeutics (formerly Seres
Health) .... Serenex
... Serionix .... Sermonix
Pharmaceuticals .... Servergy .....
SetPoint Medical .... Seurat Therapeutics ..... Seventh Sense
Biosystems ...
SGB
Biofuels ..... SGX
Pharmaceuticals ...
Shamrock Energy ... Shape Pharmaceuticals ..... Shape Security ....
Shapeways .... Sharklet
Technologies ..... Sharp Edge Labs ..... Sherlock Biosciences
Shift Labs ..... Shift Pharmaceuticals ..... Shiloh
Labs ....Shine
Medical Technologies
... ShiraTronics ... Shore
Thing Shellfish .... Shuttle
Pharmaceuticals ..... Siamab Therapeutics .... Si-Bone ....
Sicel Technologies ...
SiCortex
... Sideris Pharmaceuticals ..... SI
Diamond Technology .... Sienna Biopharmaceuticals ..... Sierra Energy
..... Sierra Monolithics
... Sierra Nevada ...
Siga Technologies ...
SiGe Semiconductor ... Sigilon Therapeutics ....
Sigma Labs
(NM) .... Sigma
Technologies .... SignalFX (formerly Signal Fuse) ..... Signal Genetics
.... Signature
Genomic Laboratories
... Sila Nanotechnologies .... Silarus Therapeutics
.... Silatronix ..
Silent
Power ... Silicon Biosystems Menarini ..... SiliconBlue
....
Silicon Laboratories ...
Silicon
Mountain
Design .. Silicon Space Technology .... Silk .... SilkTech
Biopharmaceuticals ..... Silk Tech .... Siluria
... Silverbrook
... Silverback ..... Silvergate Pharmaceuticals .... Silver
Spring Networks
... Simbol Materials ... Simply Incredible Foods ... SiMPore
...
Simulation
Technology and Applied Research ... Simulution
... Singlera Genomics ..... Singulex ... Sinmat
... SiNode Systems .....
Sintact Medical Systems
..... Sion
Power
... SiOnyx ... Sioux Manufacturing ...
Sirga Advanced
Biopharma .... Sirion Therapeutics ...
Sirnaomics ..... Sirna
Therapeutics ... Sirtris Pharmaceuticals ... Sisu Global
Health
..... Sitari Pharma .....
Skybox Imaging .... Skyhawk Therapeutics ..... Skyline Medical
....
Skyonic
... SLI .. SLIPS Technologies .....
SmartCells
... Smart Modular
Technologies ... SmartSpark Energy Systems ...
Smart
Structures .... Smart Wires ..... SmartZyme BioPharma ....
Smisson-Cartledge Biomedical ...
Smooth-Stone
...
SNP Bio ..... Socrates Health Solutions .... Sofregen ....
Soft Machines
....
Soft Robotics ..... SoftSwitching
Technologies
... Soft Tissue
Regeneration ... Soladigm (now View) ..... SolAero
Technologies ..... Solaicx ....
Solais Lighting
....
Solana Surgical ..... SolaranRx ..... SolarBridge
Technologies ... Solar Connection ....
Solarea .....
Solaria ...
Solarmer
Energy ...
Solar Power Technologies ... SolarWinds
... Solazyme
... Solexant ... Solexel ... SolFocus ... Soliant
... Solid Biosciences .... Solid Concepts ..... SolidEnergy
....
Solidus Biosciences
..... SolidWorks
... Soliris .... Soliton ..... Solixia
... Solix
Biofuels
... SolMap
Pharmaceuticals ... SoloHealth ... Solomon
Technologies
... Solo Power .... Solstice Biologics .... Soluble Therapeutics ....
Solx ....
Solyndra ... Soma .... SomaDetect .... SomaLogic
.... Somatic Labs
..... Somaxon
Pharmaceuticals .... Somerset Therapeutics .... Somna Therapeutics ...
Sonalysts ....Sonavex .... Soneter .... Sonex Aircraft ... Sonitus
Medical
... Sonivate ..... SonoSite
... Sonovex .... Sontra Medical ... Sonus
Pharmaceuticals
...
Sophiris
Bio .... Sophono ..... Soraa .... Sorrento Therapeutics ....
Soteira
... Sostena .... Sotera Wireless ... Sound Pharmaceuticals
.....
Sourcefire
... Source MDx
... Southwall Technologies ... Southwest Windpower
...
Space Dev ...
Spaltudaq ... Spansion .... Sparkbuy ..... SparkCharge .... Spark
Therapeutics ....
Sparo Labs .....
Spatial Photonics
...
SPEC ..... Spectra254 .... Spectragenetics .... Spectral Energies .....
Spectral
Systems .....
Spectranetics ...
SpectraWatt ... Spectro Coating ... SpectrumS4 ....
Speech
Tails ... Speer Medical .... Spero Therapeutics ..... Spinal
Modulation ..... Spinal
Restoration
... Spinal Simplicity ..... Spinal
Stabilization Technologies ..... SpineEX .... SpineGuard ...
Spineology
... Spine Wave .. Spintech .... Spin
Transfer
Technologies ....
SpiralGenetics .... Spiral Therapeutics .... Spiration
... Spire
... Spirox (formerly Nasoform) ..... Spoonflower .... Spotfire ... Spot
On Sciences ...
Spredfast
... Spring Bank Pharmaceuticals ... SpringLeaf Therapeutics
... SpringWorks .... SpringWorks Therapeutics ....
SPR Therapeutics
.... Spyrix ....SQZ
Biotech ..... SRL ... Staktek Holdings ... Standard
Bariatrics .... STAR Cryoelectronics
... Starfire ... Startech Environmental
... Startup Circle Pharma .... StarVision
Technologies .... Stasys Medical ..... SteadyMed Therapeutics
..... Stealth BioTherapeutics ..... Stealth
Therapeutics ... Steel City Optronics ....
Stellaray
.... Stellar Biotech .... Stellar Science ....
Stellent .... Stemagen ... StemBioSys .... Stem Cell Assurance (Now
BioRestorative Therapies) .... StemCells
... Stemcentrx ..... StemCo
Biomedical ... Stemgent ...
StemImmune ....
Stemina Biomarker
Discovery ... Stemonix ..... Stem Pharm .... Stereotaxis ...
Sterilmed ...... Sterling
Semiconductor ..... StimMed ..... Stirling Energy .... Stoke
Therapeutics ..... Stottler
Henke ... Straight Flight .... Stratagene ... Strata Oncology
..... Stratasys
... Stratatech
... Strategic Response Initiatives .... Stratos
Genomics
... Strella Biotechnology ..... StrideBio ....
Stromedix ....
Strongbridge
Biopharma .....
Sucampo Pharmaceuticals ..... Summit
Technology
.... Sun BioPharma ..... Sun Catalytix
.... Sunesis
Pharmaceuticals
.... SunHealth Solutions ... Suniva ....
Sunovion
Pharmaceuticals
... SunPower ... Sun Power Biodiesel ...
Sunrise
Ridge Algae ....Sunshine Heart .... Suntech ...
Sunvapor .... Suono ..... Superconductive
Components ... Superconductor Technologies ... SuperDimension ...
SuperFlex ..... Superior
Organoid Technologies ..... Supernus
Pharmaceuticals .... SuperPower ... Superprotonic
.... SupraSensor .....
Surefire
Medical
.... Surface
Logix
... Surface Oncology ..... Surgient ...
SurgiQuest
.... Surmet
... SurModics ... Suro Biopharma .....
Suros Surgical Systems
..... Surrozen .... SURVICE Engineering ..... Sustainable
Bioproducts .... Sustainable Oils ....
SustainX ... Sutro Biopharma ..... Sutron .....
SutroVax ..... SuturePro
Technologies (now Ceterix) .... SuviCA .... SuVolta ... Suzlon Rotor
... SVS
... SPEC ... Swallow Solutions .... SweetSpot Diabetes Care
... Swift Biosciences .... Swift Coat ..... Syagen Technology
... Symbiomix Therapeutics ..... Symbiont Web
...
Symbotic ...
Symetrix .... Symic Biomedical ..... Symyx
Technologies
... Synack .... Synageva BioPharma ... SynAm Vaccine
....
SynapDx
....
Synaptics ... SynCardia Systems ..,.. Synchroneuron ....
SynchroPET .... Syndax
Pharmaceuticals
... Syndexa Pharmaceuticals .... Synedgen ....
Synergy
Biomedical
....
Synergy Pharma ..... SynGen .... Synlogic ..... Synopsys .... SynSonix
.... Synta
Pharmaceuticals ... Syntax-Brillian ... SyntheMed
... Synthetic Biologics ..... Synthetic Genomics
.... SyntheZyme .....
Synthorx ....
Syntimmune ..... Syntrix
Biosystems .... Syntronics .... Synvitrobio ..... Syros
Pharmaceuticals .... Sysgain .... Syslogic .... Systagenix Wound
Management .....
Systems and Processes Engineering
SPEC ... Systima Technologies ..... Sytera
T2
Biosystems ... T3D Therapeutics ..... Tabula ... Taconic
BioSciences ..... Tactical Engineering and Analysis ..... Tactile
Systems
Technology .... Tactiva Therapeutics ..... TAI Diagnostics .....
Talaris Therapeutics .... Talecris Biotherapeutics
... Talee Bio ..... Taligen Therapeutics
...
Talima Therapeutics ... Tal Medical ... Talon Therapeutics
... Tandem Diabetes Care ...
Tangen Biosciences
..... Tango
Therapeutics ..... Tanox ..Tantaline
.... TapImmune .... Tarari ...
.Targacept ...
TargeGen
... Targ-Anox ... Targanta
... Targazyme (formerly)America Stem Cell....
Targeson
... Targeted Genetics ... Targeted Growth
... Taris Biomedical .... Tarveda Therapeutics
..... Tascent .... Tauriga
Sciences
.... Taxa Biotechnologies ..... Taxon
Biosciences .... Taxus
Cardium (formerly Cardium Therapeutics) ... Taylor
Devices .....Taysha Gene Therapies .... TCR² Therapeutics ..... TDA
Research .... Tealium ..... TearScience
... TearSolutions .... Tech-X ....
Techniscan Medical Systems
... Technology
and Devices Int'l ... TechTol Imaging ... Tectus ..... TELA
Bio .....
Telecardia ...
TeleContinuity ... Telefactor ..... Telemedicine
Up Close operates as DxUpClose ...... Telik ... Tempest
Therapeutics ..... Templex
Technology... Tempus ..... Tenax Therapeutics .... Tenaya
Therapeutics ..... Tendril
...
Tendyne
Holdings ..... Tensha Therapeutics ...
Tepha
... TeraDiode .... TeraDiscoveries (now Cloud
Pharma) ....
Terapio ... TeraStor ...
Terrabon ...
Terrajoule ... TerraMetrics ... Terumo BCT .... Terus
Technologies .... TESARO ....
TeselaGen
Biotechnology .... Tessera
Technologies ... Tethys BioScience .... Tetra
Discovery
Partners .... Tetragenetics
... TetraLogic Pharmaceuticals ...
Tetraphase
Pharmaceuticals ... TetraVue ... Tezzaron
Semiconductor .... TFF Pharmaceuticals .... TGS Knee Innovations
... TG Therapeutics .... Thar Pharma .... Thalchemy ..... The
ExOne .... The Medicines ..... Therabron Therapeutics ..... Theraclone
Sciences
...
Theragenics
.... Therametric Technologies ... Theranos
....
Therion
Biologics ... Thermacore ... Thermage
...
Thermal Gradiant .... Thermal Spray Technologies
....
ThermalTherapeutic Systems
... Thermedical ...
ThermoAura ....
ThermoCeramiX .... ThermoGenesis .... Thermon ... TherOx ....
Thesan
Pharmaceuticals .... Theseus...
Thetis Pharmaceuticals ...
ThingMagic... Third Wave Technologies .. Thoratech
Tech
... Thorley Industries .... ThreeRivers 3D ..... Threshold
Pharmaceuticals .... Thrive Earlier Detection .....
ThromboVision .... Thyritope Biosciences
.... Tiax ... Tibbetts Industries
... Tibion ..... Tiburio
Therapeutics ..... Tilera ... Tillges
Technologies ... Tilos Therapeutics .... Tioma Therapeutics .....
TissueGene ..... TissueLink
... Tissue Regeneration Systems .... Titan
Pharmaceuticals .... Titan Spine ..... TJ Technologies .... TLC
Precision Wafer
... Tmunity Therapeutics .... Tobira Therapeutics ....
Tocagen
...
Tokai Pharmaceuticals .... Tolerx .... TomoTherapy
... Tone Tree ..... Topia Technology .... TopicalRemedy ....
Topokine Therapeutics
.... Torax
Medical ... Torque Therapeutics ..... Total Immersion
...
TotipotentRx .... Totus Solutions .... Toyon Research ..... TP
Therapeutics ..... Trace
Genomics ..... Tracon
Pharmaceuticals
... TranS1
.... TransAstra .... Transatomic Power .... Transcend Medical
...Transcept Pharmaceuticals .... TransCorp
..... Transcriptic ..... TransEnterix ... Transgenomic
... Translattice ..... TransMedics
... Transmeta ... TransMolecular
... Transphorm .....
TransTech
.... TransTech Pharma (now vTv Therapeutics) ... Transzyme
Transzyme Pharma ... Travecta Therapeutics .... Traverse
Biosciences ... Traycer
Diagnostic Systems ..... Trefoil Thera .... Trellis
Bioscience
... Trellis Earth Products ... Trethera
.... Trevena
... Trevi Therapeutics ..... Trex Enterprises ... Triad
Semiconductor .... Tri Alpha
Energy ..... Triangle
BioSystems .... Tribogenics
....
Tribologix
.... Trice Medical .... Trice
Orthopedics .... Tricida ..... Trident Systems ... Trilumina ....
Trimble Navigation
.... Trimeris
... Triplet Therapeutics .... Triquint Semiconductor ...
Triton Systems ... Trius Therapeutics ...
TriVascular
Technologies .... Trovagene ..... Trubion
Pharmaceuticals ... Trucode
Gene Repair .... Tru-D SmartUVC ..... True Bearing Diagnostics ....
True Diagnostics
....
True Health Diagnostics
.... True North Therapeutics .... Truestone ..... TruTouch Technologies
..... Try Eco ..... Tryton
Medical
... TScan Therapeutics ..... Tularik .... Turtle Mountain
Communications .... TVA Medical
... Tvardi Therapeutics .... Twelve .... Twentyeight-Seven
Therapeutics ...... Twin Star Medical ... Twist
Bioscience
..... TwoXAR ..... Tyme Technologies .... TypeZero Technologies
....Tyra Biosciences .... Tyrosine Pharmaceuticals .... Tyrx
uBiome .... UCAN
... UES
... Ulthera .... UltraCell ... Ultragenyx
....
Ultralife Batteries
...
Ultramet... Ultradian
Diagnostics ..... Ultraviolet Sciences ... Unbounded Robotics
.... Unchained Labs .... UNIAX
... Unica
... Unidym ... UniEnergy Technologies ..... Unified
Nexsys
.... Unilife ..... Uni-Pixel .... Uniqure
.... United
Devices ... United
Therapeutics
... United Therapies ..... Unity Biotechnology .... Universal
Cells ...... Universal
Display ... Universal
Robots ..... Universal
Technical Resources .... Universal
Technology .... Unleash Immuno
Oncolytics ..... Unum Therapeutics .... Unwired
Nation ... Uptake Medical
... UQM Technologies ... Urbix Resources ....
Urigen
Pharmaceuticals
.... UroGene Pharma ..... US
Nanocorp ... Uroplasty ..... US Bioscience ..... US
Silicones ... UTC Power .... Utilidata ... Utron
.....
UVision360
Vaccinex .....
Vaccinogen .... Vader Systems ..... VakSea ....
Vala Sciences
....Valencell ... Valence Technology .... Validity
Sensors
... Valmont Industries .... Valulytics .... Vanda
Pharmaceuticals
... Vanguard Space Technologies ..... Vapogenix ..... Variant
Pharmaceuticals ..... Vascudyne ..... Vascular
Biogenics (also VBL Therapeutics) .....
Vascular
Designs ... Vascular Genesis ..... Vascular Pathways
...
Vascular Pharmaceuticals ....
Vascular Solutions .....
Vasculox .... VasoGenix
Pharmaceuticals ... Vasoptic Medical ..... Vast Therapeutics
.... Vativ
Technologies ... Vaxart ... Vaxess
Technologies ....
VaxGen
... VaxNewMo ..... VaxInnate ... vCalc
.... Vecna Tech ...
Vectorlogics
....
Vedanta
Biosciences
.... Veeva Systems .... Veezyon
... VeinAid ... Velano Vascular .... Velicept
Therapeutic
..... Velocimed ...
Velomedix
... VelosBio ..... VenatoRx Pharmaceuticals ..... Venaxis
..... Vendormate
....
Veniti ... Vensun
Pharmaceuticals ....
VentiRx
...
Ventria Bioscience
... Ventrix ..... Ventrus
Biosciences ... Ventus Therapeutics .....
Veracode
... Veracyte
... Veralox Therapeutics .... Veran Medical Technologies
..... Verastem
... VeraSun Energy
... VerAvanti .... Verax
Biomedical ... Verdezyne ... Vergent Bioscience .....
VerinataHealth ...
Verenium ... Vericel (formerly Aastrom Bio) .... Verifica-BG
... Veritas Genetics .....
Vermillion .... Vermont
Composites ...Veros Systems ... Verrica Pharmaceuticals .... Versar
.... Versartis ... Verseau
Therapeutics ... Vestagen Technical
Textiles .... Vestaron .... VerteCore ..... VerteraSpine ..... Vertex
Pharmaceuticals ... VeruTEK Technologies ... Verve
Therapeutic .... Vesper
Medical
..... Vextec
... VGBioCogCubed .... V-Glass .... VGo
Communications ... VGX Pharmaceuticals ..... ViaCell
... ViaCyte
.... Viacor
.... Viamet Pharmaceuticals
... ViaSat
... Via Separations .... Vical . .. Vicarious .... Vicus Technologies
.... Vidacare VIDA Diagnostics ..... ... View .....
Vigene Biosciences .... Viking
Therapeutics .... Vion
Pharmaceuticals
... ViraCor Laboratories ... Viracta Therapeutics ..... Viral
Genetics ....
Vir Biotech .... Virdante Pharmaceuticals
...
Virdia
.... Virent Energy Systems ... Viresco Energy
... Virobay .... ViroPharma . .. ViroXis ...
Virtify ... Virtualitics .... VirtualScopics
.... Virtusa
... Viscardia ..... VisEn Medical ... VisiGen
Biotechnologies
... VisionGate ..... VisionQuest ..... Vision-Sciences
... Vistagen
Therapeutics ... Vistec
Lithography ... Visterra ...
Visualase .... Vitae Pharmaceuticals ..... VitalMedix
... Vital Therapies ...... Vital Vio .... VitaPath Genetics
... Vitriflex .... Vium ..... Vivex Biomedical
.... Vividion Therapeutics ..... Vivisimo .... Vixar
... Vixel ... Vixiar Medical ..... Vizgen ... Vizzario ....
Vlingo
... VLST ..... VMware ... Voci Technologies .... Volcano ....
Voltron
Therapeutics .... VoltServer ... VORAGO Technologies
(previously Silicon
Space Technology) ..... Vorbeck Materials
... Vor BioPharma ..... Vortex Biosciences ..... Vortex
Medical
... Voxel
.. voxeljet ..... Voyager Therapeutics
.... Vtesse ....
VT
Silicon
.... vTv Therapeutics (formerly TransTech Pharma) ..... VUV Analytics
.... Vuzix .... Vyriad .... Vyrx
Pharmaceuticals ..... VytronUS
WaferGen
Biosystems ...
Wakonda Technologies ... Walker Magnetics Group ...
Waste2Watergy
.... Waveband
..... Wave Computing ..... Waveguide ..... WaveRx ... Weinberg Medical
Physics .... WellStat
Therapeutics .... Werewolf Therapeutics ..... Whole Biome ..... Whole
Trees
.....
WiBotic .... Wicab ..... Wickr ... WildcatDiscovery ....
Wiliot .....
Willow Garage
...
Wilocity
.... Wilson
Greatbatch
.. Wilson Tool International .... Wilson Wolf Manufacturing
...
WiMax.com ...
Windlift ... Windtree
Therapeutics ..... WinSanTor .... Wintegra ... WISErg .... Wizbe
Innovations ...
WMR
Biomedical (now Arsenal Medical) ... Wolf Technical
Services ... WoundZoom .... Woven Orthopedic Technologies
....
Wright Materials Research
... Wright Therapy Products ..... W Solar
Group
X4 Pharmaceuticals .....
Xanofi ... Xanthus
Pharmaceuticals
... XBiotech USA ..... X-Biotix Therapeutics .... X-Body
Biosciences
... Xcede Technologies ..... XCELL BIOLOGIX .....
Xcell Biosciences
....
Xcellerex ... XChanger
Companies .... Xencor .... X-energy ..... Xenetic Biosciences ....
Xenex
Disinfection Services .... Xenex
Healthcare Services ... XenoGen Biosystems .... Xenomics
... Xenoport ... Xeris
Pharmaceuticals ... Xetrios Therapeutics .... XF
Technologies .... xG Technology .... Xidex ... Xilio Therapeutics
(formerly Akrevia Thera) .... Xitronix
... XL
Hybrids ... Xlumena .... Xoc Pharmaceuticals ..... Xollai ...
Xolve
(formerly
Graphene Solutions)
... Xoma
... XProSciences (now Icagen) ..... X-Ray Optical .... X-Spine
.... XSunX
...
Xtalic .. Xtant Medical
Holdings ..... Xtent ...Xtreme Power
... XTuit Pharmaceuticals ....
Xunlight .... XyloCor Therapeutics .... Xynomic
Pharma
Yan Engines ... Yardney Technical Products .... Y-Carbon ... Yulex .... Yumanity Therapeutics .... Yurie