Bio-Path Holdings up 19% [Mar 22, 19]
GRO Biosciences, a Harvard Life Lab spinoff startup co-founded by geneticist George Church raised $3.7M in a new round of equity funding, according to a Form D filing. [DCInno, Mar 22, 19]
startup TearSolutions (Charlottesville, VA; no SBIR, founded 2015) is moving ever closer to commercialization after hauling in a $6.4 million funding round. The company, which launched in 2013 as a spinout of the University of Virginia, is developing a drug called Lacripep to combat dry eye. [Kieran McQuilkin, Richmond Inno, Mar 18, 19]
Pentagon: We're Buying Boeing F-15s to Keep 2 Fighter Makers in Business. ... The acting defense secretary's ties to the company had nothing to do with the decision, a senior defense official said. [Marcus Weisgerber, Defense One, Mar 25, 9] Oh, right.
Liquidia Tech down 19% [Mar 21, 19]
Turning Point Therapeutics (San Diego CA; no SBIR, founded 2013), a clinical-stage precision oncology company designing and developing novel drugs to address treatment resistance, announced it has filed [for IPO] [company press release, Mar 21, 19] total funding $144M [crunchbase.com] plans to raise $100M [Bradley Fikes, San Diego Union Tribune, Mar 21, 19]
Sherlock Bioscienecs (Cambridge, MA; no SBIR) dedicated to making diagnostic testing better, faster and more affordable, today announced its launch and initial financing of $35 million. ... using Engineering Biology tools, including CRISPR and Synthetic Biology, to create a new generation of molecular diagnostics that can rapidly deliver accurate and inexpensive results for a vast range of needs in virtually any setting. [company press release, Mar 21, 19]
Karuna Therapeutics (formerly Karuna Pharmaceuticals, Boston, MA; no SBIR), focused on targeting muscarinic cholinergic receptors for the treatment of neuropsychiatric disorders including psychosis in schizophrenia, psychosis in Alzheimer’s disease, and pain, announced the completion of a $68 million Series B [company press release, Mar 18, 19]
Vixiar Medical (Annapolis, MD; no SBIR) dedicated to the development of non-invasive devices and systems for monitoring cardiopulmonary diseases, announced today that it closed its most recent financing of $1.5 million to complete an ongoing clinical trial and to prepare regulatory submissions. [company press rleaase, Mar 21, 19]
researchers from Memorial Sloan Kettering Cancer Center, MD Anderson Cancer Center and Dana-Farber Cancer Institute have joined forces with DNA sequencing giant Illumina and its liquid-biopsy spinoff Grail to develop a new assay. According to results published in the journal Annals of Oncology, they've come up with a method that can detect mutations in NSCLC patients’ blood with high sensitivity. [Angus Liu, Fierce Biotech, Mar 20, 19]
Flagship Pioneering (Cambridge, MA) has raised $824 million for a fund to support biotech and health companies that have come up through its Flagship Labs foundry. [Amirah Al Idrus, Fierce Biotech, Mar 20, 19]
Employees as commodities. Trump proposes to integrate the functions of the Office of Personnel Management into the General Services Administration, Defense Department and the Executive Office of the President, although much remains contingent on Congress approving legislation. [Erich Wagner, govexec.com, Mar 21, 19] Don't expect Congress to agree to remake USG into Trump Tower Inc with an arbitrary dictator.
Cytokinetics up 19% [Mar 20, 19]
Catalyst Pharma up 16% [Mar 20, 19]
Bio-Path Holdings down 15% [Mar 20, 19]
Zynerba Pharma up 15% [Mar 19, 19]
resTORbio down23% [Mar 19, 19]
Cree is selling its entire lighting division to Ideal Industries Inc. in a $310 million deal [Lauren Ohnesorge, Triangle Business Journal, Mar 15, 19]
Cubic announced the acquisition of Nuvotronics [Duham, NC and Radford,VA; $27M SBIR, founded 2008), a disruptive technology provider of microfabricated radio frequency (RF) products, for approximately $64 million in cash .... The cornerstone of Nuvotronics’ innovation platform is their patented PolyStrata® technology, which was developed under DARPA and enables the company to design and produce uniquely packaged RF devices, such as antennas, filters and combiners [Cubic press release, Mar 14, 19]
All the federal government’s initiatives and resources around [AI] can now be accessed on one dedicated website, AI.gov, which the White House launched. [Brandi Vincent, nextgov.com, Mar 19, 19]
Governor Cuomo announced companies in 43North’s portfolio have created more than 400 jobs in Western New York. 43North is the startup competition that invests $5 million annually to attract start-up companies to Western New York and cultivate their growth in the region. Since launching the competition in 2014, 43North has invested in 44 companies. [43North press release, Mar 7, 19]
Tech mafia: In Silicon Valley’s tightknit club, success typically hinges on whom you know. Employees of tech startups frequently leave the companies once they have been enriched by their firms’ [IPO]s networks of alumni from these companies — called mafias — support their peers’ new businesses with hiring, advice and money. [Erin Griffith, New York Times, Mar 17, 19]
Dermira (Menlo Park, CA; no SBIR, founded 2010) up 84% [Mar 15, 19] generated evidence that its treatment for moderate-to-severe atopic dermatitis can pose a challenge to Dupixent. [Fierce Biotech, Mar 18, 19] total funding $130M [crunchbse.com]
Phase Bio Pharma up 67% [Mar 18, 19]
Atossa Genetics up 25% [Mar 18, 19]
Aerpio Thera (one SBIR) down 71% [Mar 18, 19] announced that Administration of AKB-9778 twice daily did not meet the study's primary endpoint of the percentage of patients with an improvement of two or more steps in the study eye diabetic retinopathy severity score (DRSS) compared to placebo. [company press release, Mar 15, 19]
Synaptics down 23% [Mar 18, 19]
QR Pharma (Berwyn, PA; no SBIR, founded 2008) raised $530K [John George, Philadelphia Business Journal, Mar 18, 19] total funding $8M [crunchbase.com]
BioCold Genesys (Santa Ana, CA; no SBIR) developing novel immunotherapies used to treat cancer, has closed on $22 million in financing. [I-Chun Chen, LA Biz News, Mar 18, 19]
NantCell (Culver City, CA; no SBIR), a subsidiary of NantWorks, raised $30 million in investor funding after a similar injection late last year, according to a March 14 securities filing. [Dana Bartholomew, LA Business Journal, Mar 14, 19]
Trethera (Los Angeles, CA; no SBIR), a biotechnology firm raised up to $8 million from investors, according to a securities filing posted March 11. [Dana Bartholomew, LA Business Journal, Mar 11, 19] a preclinical-stage biopharmaceutical company developing cancer treatments for a range of cancers with unmet needs. [company website]
Include Us Out. U.S. semiconductor companies want no part of any trade deal that calls for stepped-up purchases from China. Washington has pressed Beijing to buy more than $1 trillion in U.S. goods and services as part of an agreement, and China has offered to buy $30 billion of U.S. chips over six years. But U.S. chip makers have told President Trump’s administration not to include them, Bob Davis reports. Why? Because U.S. production costs are so high, mandatory-purchase quotas would essentially force U.S. chip makers to open new factories in China and give Beijing bureaucrats more sway over the U.S. firms. [Jef Sparshott, Wall Street Journal, Mar 19, 19]
Magenta Thera up 26% [Mar 15, 19]
Catabasis Pharma up 16% [Mar 15, 19]
Atossa Genetics down 50% [Mar 15, 19]
Chinese investment in U.S. startups has remained resilient in recent months despite new legislation that some thought could severely hamper deal flow, according to a new report from research firm Rhodium Group, after a record $3.3 billion in 2018. [Rolfe Winkler, Wall Street Journal, Mar 15, 19]
Making government like a real estate biz. The Trump administration has long expressed a desire to make the federal non-salary compensation system more in line with private sector employers, who mostly have abandoned offering pensions to employees. .... “We believe it is the first step to eliminating any kind of defined benefit pension plan for federal employees,” [AFGE Senior Policy Counsel Richard] Loeb said. “Despite [the administration’s] claims to the contrary, they’re not doing this to enhance retirement benefits. They’re doing it to reduce their costs.” [Erich Wagner, govexec.com, Mar 15, 19]
Melinta Thera up 17% [Mar 14, 19]
X4 Pharmaceuticals (Cambridge, MA; no SBIR), a clinical-stage biopharmaceutical focused on the development of novel therapeutics for the treatment of rare diseases, announced the completion of its merger and the reverse stock split with Arsanis (Waltham, MA; no SBIR) . [X4 press release, Mar 13, 19]
AstraZeneca agreed to pay Seres Therapeutics (Cambridge, MA; no SBIR, founded 2010) $20 million up front to kickstart a three-year partnership focused on researching how tapping the gut microbiome could make cancer immunotherapies work better. [Frank Vinluan, xconomy.com, Mar 15, 19]
Regenerative medicine biotech Surrozen (San Francisco, CA; no SBIR) raised $50 million in Series B funding to continue developing treatments for liver diseases. Surrozen focuses on Wnt, a protein that plays a role in stem cell maintenance and tissue regeneration. [Frank Vinluan, xconomy.com, Mar 15, 19]
Zafgen ( Boston, MA; no SBIR) suspended plans to begin human testing of its experimental drug ZGN-1258 due to worrisome safety signs in preclinical tests. The disclosure marks another setback for Zafgen, which scrapped one drug due to safety problems and saw the FDA temporarily halt testing of another. [Frank Vinluan, xconomy.com, Mar 15, 19]
Via Separations (Somerville, MA; no SBIR), applying novel filtration to reduce the energy used in separation processes by 90%,announced the close of a $4.8 million Series A financing [company press release, Mar 14, 19]
President Trump is making the trade deficit bigger. "Pretty much anyone with a passing knowledge of macroeconomics could have predicted that this would be the likely result of moves by Trump and Congress to stimulate the U.S. economy with bigger federal deficits," Justin Fox writes at Bloomberg Opinion. "That Trump himself did not see this coming is another indication that, as someone recently said, the man doesn’t understand much about macroeconomics." [Jeff Sparshott, Wall Street Journal, Mar 14, 19] Or he simply has no connection to truth when spouting.
Ocean Power Tech down 23% [Mar 13, 19]
Phraxis (St Paul, MN; no SBIR, founded 2008), developing solutions, offers InterGraft, a percutaneously delivered arterio-venous shunt that provides a non-surgical approachfor patients who need vascular access to enable hemodialysis, raised $5.6M in a venture round ... prior funding $2.3M [crunchbase.com, Mar 11, 19].
QinetiQ North America has won a $152M initial contract to manufacture small unmanned ground robots for the U.S. Army’s Common Robotic System – Individual program, Defense News reported Thursday. QinteiQ NA and Endeavor Robotics separately developed robotic systems under the CRS-I program’s engineering and manufacturing development phase through a $429.1M contract awarded in April 2018. [Brenda Marie Rivers, GovConWire, Mar 14, 19] some of the robotics came from former SBIR champ, now Qinetic subsidiary, Foster-Miller.Trump warned Beijing he would not sign off on a trade deal that didn’t meet U.S. demands, Jong Un, Bob Davis, and Alex Leary report. ... a sharp departure from his recent optimism; it's not clear if they're a negotiating tactic or a sign of some underlying impasse in talks. [Jeff Sparshott, Wall Street Journal, Mar 14, 19] Unlike the US Congress Republicans, the Chinese don't worry about angering Trump's "base" who believe/hope in his omnipotence.
Mersana Thera up 17% [Mar 12, 19]
British medical device manufacturing company Smith & Nephew plc plans to acquire Osiris Therapeutics (Columbia, MD; $1M SBIR) for $660.5 million [cash]. ... Osiris is coming off a tumultuous three-year period in which four CEOs left the company and several former executives faced criminal charges for fraud. [Washington Business Journal, Mar 12, 19]
Prepare to
prepare. (NSF)
has instituted a new requirement
that is going to affect everyone who wants to submit a Phase I SBIR or
STTR proposal, starting immediately. And if you don’t react ASAP, you
may well be precluded from submitting a proposal in the current
solicitation “window” that ends June 13th—and you may even be precluded
from submitting if you react quickly but not well to the new
requirement. [Greenwood [SBIR] Consulting, Mar 12,
19] All
agencies have a problem with piles of proposals with no chance of
funding. Lots of work for the agency and lots of wasted work by the
proposers. Meanwhile, Trump keeps trying to chop the agencies' workers.
One solution is a clear agency message on what kinds of proposals have
a reasonable chance. Help them and yourself - see what they
fund,
learn what they want.
Refreshing techies. Modern Elder Academy [Resort] in El Pescadero, Mexico, considers “applications” for one-week programs [with] “tuition” of $5,000 ... aimed at workers in the digital economy — those who feel like software is speeding up while they are slowing down, no matter how old they really are. ... More workers are finding themselves in the curious position of presenting as old while still being — technically, actuarially — quite young. And Modern Elder sees a business opportunity in selling them coping workshops, salt-air yoga and access to a shaman. [Nellie Bowles, New York Times, Mar 4, 19]
Don't need no dadgum gummint. Thirty-five Congressional mandates sit unanswered, on everything from minimum seat space to secondary barriers protecting cockpits. The top job at the Federal Aviation Administration has been open for 14 months. Enforcement fines against major U.S. airlines have dropped 88% in the past two years, even as three-hour tarmac delays have more than doubled. [Scott McCartney, Wall Street Journal, Mar 12, 19]
Bio-Path Holdings up 54% [Mar 11, 19]
Aqua Bounty Tech down 26% [Mar 11, 19]
GTx (Memphis, TN; $300K SBIR) and Oncternal Therapeutics (San Diego, CA; no SBIR) biotechnology company developing potential first-in-class therapeutic candidates for cancers, jointly announced that they have entered into a definitive merger agreement under which the stockholders of Oncternal would become the majority owners of GTx’s outstanding common stock. The proposed merger will create a publicly-traded, clinical-stage oncology company, Oncternal Therapeutics. [joint companies press release, Mar 7, 19]
LKC Technologies (Gaithersburg, MD; no SBIR, founded 2014), biotech raising $635K of a maximum $1.2M round of equity according to SEC filings. ... makes devices for visual electrophysiology testing – measuring retina function to diagnose eye diseases and disorders. ... brings total funding to $3.8M. [Kieran McQuilkin, DCInno, Mar 11, 19]
Always about "me". Trump: Making daylight saving time permanent is ‘OK with me’ [AP News, Mar 11, 19]
AquaBounty Technologies (Maynard, MA; no SBIR) up 118% [Mar 8, 19] focused on enhancing productivity in the aquaculture market and a majority-owned subsidiary of Intrexon, announces the [FDA] lifting of the Import Alert, allowing the Company to start farming AquAdvantage Salmon in Indiana. ... Approximately 350,000 tons of Atlantic salmon are consumed in the United States with more than 95% of it imported. FDA's actions will allow for production and sale to begin here in the U.S., bringing opportunity for investment in rural America [company press release, Mar 8, 19]
Ra Pharma up 19% [Mar 8, 19]
Bio-Path Holdings down 46% [Mar 8, 19]
Translate Bio down 19% [Mar 8, 19]
AMAG Pharma down 18% [Mar 8, 19]
The Army is all in on innovative startups, but it will likely rely on tried and true contractors to get the tech over the finish line, Lt. Gen. Eric Wesley told SXSW. [nextgov.com, Mar 9,19] As usual, the military wants new ideas that have been thoroughly tested. Advantage: established companies. But then, the Army could be at war tomorrow in any climate, especially with a loose-cannon President.
‘The comic thing about this drama is that no one is even pretending there is a real emergency.” So says Neeraj Kaushal, 57, a professor of social policy at Columbia who has just published a bracing book on U.S. immigration policy. Her thesis: Far from presenting an emergency, as President Trump contends, America’s immigration system is the best in the world. [Tunku Varadarajan, Wall Street Journal, Mar 8, 19] Except for Trump's view as he echoes his "base." Unfortunately, Trump is classic political theatrical exploiter of convenient myths. The real Trump is playing a character called Trump who is anti immigrant because thats what the voters in middle America want. [commenter, WSJ,Mar 9, 19]
Bio-Path Holdings up 223% [Mar 7, 19]
Altimmune up 50% [Mar 7, 19]
Harpoon Thera down 18% [Mar 7, 19]
Beam Therapeutics (Cambridge, MA; SBIR, founded 2017) developing precision genetic medicines through base editing, today announced the successful completion of a $135 million Series B financing [to] to advance the company’s development of next-generation CRISPR technologies, expand its pipeline of base editing programs, and further extend its scientific and technical leadership. [company press release, Mar 7, 19] prior funding $87M [crunchbase.com]
Erasca (San Diego, CA; no SBIR, founded 2018) dedicated to advancing exceptional scientific approaches to erase cancer, has closed an extension to its Series A financing round, bringing the total raised to $64 million [to] support the company's efforts to potentially in-license new investigational compounds in development, while also accelerating the buildout of Erasca's artificial intelligence (AI) platform that will drive discovery and development of a new generation of oncology drugs designed to not just treat, but actually cure, cancer. [company press release, Mar 5, 19] prior funding $42M [crunchbase.com]
Ambrx (San Diego, CA; no SBIR), a clinical-stage biopharma focused on the development of innovative protein therapeutics and BeiGene, (China), a commercial-stage biopharmaceutical company focused on developing and commercializing innovative molecularly-targeted and immuno-oncology drugs for the treatment of cancer, announced a global research and development collaboration. ... Ambrx will receivean upfront payment of US$10 million to fund the initial discovery and research activitiesand additional upfront payments of up to US$19 million if BeiGene elects to initiate additional programs. [company press release, Mar 6, 19] prior funding $147M [crunchbase.com]
Buy American goes to China. The Sichuan provincial government has stipulated that for 15 types of medical devices, hospitals will be reimbursed only for procedures that use Chinese-manufactured devices. [ELIZABETH C. ECONOMY, Foreign Affairs, Mar 6, 19] With Trump alienating all and sundry, China will look more and more attractive to other countries despite Xi's control fetish.
Bio-Path Holdings up 160% [Mar 6, 19] announces a clinical update to the previously reported interim analysis from the Phase 2 trial of prexigebersen (BP1001) for the treatment of acute myeloid leukemia (AML) and provides its plans for the compound's clinical development moving forward toward registration. [company press release, Mar 6, 19]
Proteon Thera up 21% [Mar 6, 19]
Synthorx down 17% [Mar 6, 19]
G1 Thera down 16% [Mar 6, 19]
Ceradyne (3M subsidiary since 2012, $4.4M SBIR, founded 1967) awarded [one of three] spots on a potential $704.2M contract to supply hard armor plates to the U.S. Army. [Brenda Marie Rivers, GovConWire, Mar 7, 19]
Axial Biotherapeutics (Boston, MA; no SBIR, founded 2016 with $19M) with roots at the California Institute of Technology raised $25 million in a Series B round. .... has licensed rights to central nervous system biotherapeutics from the Mazmanian Laboratory at Caltech. [Dana Bartholomew, LA Business Journal, Feb 27, 19]
Endo International plc (Irish) announced that its subsidiaries have terminated their respective agreements to acquire Somerset Therapeutics (Somerset, NJ, no SBIR, founded 2015) and the business of its India-based affiliate Wintac Limited, which operates as Somerset Therapeutics' contract developer and manufacturer. There are no penalties or other payments associated with terminating the agreements. [Endo press release, Feb 27, 19]
Aqua Metals up 20% [Mar 5, 19]
Bionano Genomics (San Diego, CA; $4M SBIR) up 19% [Mar 5, 19], a life sciences instrumentation company that develops and markets Saphyr®, a platform for ultra-sensitive and ultra-specific structural variation detection in genome analysis, announced the publication of the largest study of human genomes on its platform to date. [company press release, Mar 5, 19]
Cerecor down 20% [Mar 5, 19] announced sale of common stock
Yield Lab, an agribusiness accelerator based in Creve Coeur [MO], has chosen six software and ingredients companies for its spring class. ... includes two firms from the St. Louis area, three from elsewhere in the United States and one from Argentina. Each gets a $100,000 investment and participates in a business development program at Yield Lab's headquarters. ... Arch Innotek (St. Louis, MO; $300K SBIR) uses a fermentation process to produce natural ingredients. ... VakSea (Baltimore, MD; no SBIR) sells immune-boosting proteins for shrimp aquaculture. [David Nicklaus, St Louis Post Dispatch, Feb 28, 19]
Anything Goes. When America, the world’s most influential democracy, has a leader without shame, who is backed by a party without spine willing to prostitute itself to Trump no matter how low he goes — and both are protected by a virtually state-run network without integrity, called Fox — it becomes a hunting license for leaders everywhere to go after their own domestic opponents and cross any human rights redline to stay in power. [Tom Friedman, New York Times, Mar 6, 19]
Luna Innovations (Roanoke VA; $180M SBIR, 200 employees) up 17% [Mar 4, 19]
Vusix up 15% [Mar 4, 19]
Precision BioSciences (Durham, NC; $500K SBIR, 130 employees) files plans for $100 million IPO. [Raleigh News & Observer, Mar 4, 19]
Mechanical Technology (Latham, NY; $200K SBIR) declared a cash dividend of $0.37 per share, .. the first dividend in the Company’s 58 year history. [company press release, Feb 26, 19]
Bio-Path Holdings (Bellaire, TX; no SBIR) up 197% [Mar 1, 19] a biotechnology company leveraging its proprietary DNAbilize(R) antisense RNAi nanoparticle technology to develop a portfolio of targeted nucleic acid cancer drugs, today announced an upcoming poster presentation at the 2019 American Association for Cancer Research (AACR) Annual Meeting [company press release, Mar 1, 19] total fundng $2.3M [crunchbase.com]
Apellis Pharma up 21% [Mar 1, 19]
XBIOTECH up 18% [Mar 1, 19] announced breakthrough results from its Phase 2 clinical trial of its antibody therapy, bermekimab [company press release, Mar 1, 19]
Editas Medicine up 15% [Mar 1, 19]
A phase 3 trial of ImmunoGen’s antibody-drug conjugate mirvetuximab soravtansine has missed its primary endpoint. The ADC failed to extend progression-free survival by more than chemotherapy. [Nick Paul Taylor, Fierce Biotech, Mar 1, 19]
Axial Biotherapeutics (Waltham, MA; no SBIR, founded 2016) dedicated to building a unique class of gut-targeted programs for neurodegenerative and neuropsychiatric diseases, today announced the completion of a $25 million series B equity financing. [company press release, Feb 27, 19] prior funding $19M [crunchbase.com]
Novavax’s RSV shot missed another phase 3 trial, causing the company’s stock price to lose about two-thirds of its remaining value premarket [Conor Hale, Fierce Biotech, Feb 28, 19]
Inovio Pharma spinout Geneos Therapeutics (Plymouth Meeting, PA; founded 2016) closed a $10.5 million first-round financing that will help launch its R&D in neoantigen-targeting cancer immunotherapies. [Phil Taylor, Fierce Biotech, Feb 22, 19]
Hunkering down. DOE has drafted new restrictions on research collaborations between the scientists it funds and certain foreign governments suspected of trying to steal sensitive technologies. DOE officials are still debating the scope of the new rules. [Jeffrey Mervis, Science, Feb 15, 19]
Like Spain in 1796, the U.S. is at the apparent apogee of its power, consciously facing a post-hegemonic future but uncertain about how to proceed. Like the Spanish monarchy then, the U.S. today is riven between hostile constituencies—radical and reactionary, Christian and secularist—with no formula for reconciling them. [Felipe Fernández-Armesto reviewing Carrie Gibson's El Norte and Robert Goodwin's America, Wall Street Journal, Mar 2, 19]
Arcadia Biosciences up 49% [Feb 28, 19] announced the company will apply its expertise to a new crop: cannabis. With the establishment of Arcadia Specialty Genomics(TM), the company is dedicating a first-of-its-kind strategic business unit to the optimization and standardization of cannabis plant content, quality, climate resiliency and yield. [company press release, Feb 28, 19]
TG Therapeutics (New York, no SBIR) up 31% [Feb 28, 19] announced that it intends to sell [common] shares in public offering. ...announced that it has entered into a debt financing agreement for up to $60.0 million ... also announced that the Marginal Zone Lymphoma (MZL) cohort of the UNITY-NHL Phase 2b pivotal trial evaluating umbralisib (TGR-1202), our novel, once daily, PI3K delta inhibitor, met the primary endpoint [company press release, Feb 28, 19]
Mersana Thera down 20% [Feb 28, 19]
Applied Optoelectronics down 17% [Feb 28, 19]
StemoniX (Maple Grove, MN; no SBIR, founde 2014), a biotech startup using stem cells to create micro-organs for drug testing and development, has raised $14.4 million in a secured $14.4 million in Series B funding .... seeks to transform conventional drug development via ready-to-assay plates containing functioning microOrgans®, including active neural circuits (microBrain®) and beating heart cells (microHeart®) [company press release, Feb 28, 19] prior funding $12 [crunchbase.com]
Ionis Pharma up 15% [Feb 27, 19]
Energous down 24% [Feb 27, 19]
Immunogen down 20% [Feb 27, 19]
Maze Therapeutics (San Francisco, CA) is launching with $191 million from investors led by Third Rock Ventures and Arch Venture Partners, both known for pouring tens of millions of dollars into new high-risk companies. Maze is looking at diseases where, in rare cases, a modifier gene is improving or even eliminating the symptoms stemming from a disease-causing gene. [Ben Fidler, xconomy.com, Feb 27, 19]
Sarepta Therapeutics has been steadily building up its gene therapy capabilities for a few years now, and it took two more steps forward on that front this morning. First, it exercised an option to buy gene therapy startup Myonexus Therapeutics (New Albany, OH; no SBIR) for $165 million. And then it disclosed early human results from the first program to come from the deal, a potential treatment for a form of Limb-Girdle Muscular Dystrophy (LGMD), a progressive, deadly genetic disease with no available treatments. [Ben Fidler, xconomy.com, Feb 27, 19]
Kaleido Biosciences (Bedford, MA; no SBIR, founded 2017), a clinical-stage healthcare company with a differentiated, chemistry-driven approach to leveraging the potential of the microbiome organ to treat disease and improve human health, announced the pricing of its [IPO]... expected to be $75 million. [company press release, Feb 27, 19]
CyTomx Thera down 19% [Feb 26, 19]
Energous down 31% [Feb 26, 19]
startup Dianomi Therapeutics (Madison, WI; no SBIR) draws a $3M investment .... says it has a new way to make prescription medications pack a bigger punch — to help not only humans but injured pets or technology combines drug candidates with mineral-coated microparticles. It is based on the concept that minerals in bones and teeth stabilize proteins and extend their staying power. [JUDY NEWMAN, madison.com, Feb 24, 19]
Motif, a startup that's a subsidiary of biotechnology major Ginkgo Bioworks, launched today with $90M Series A in its pocket to make alternative proteins. [DCInno, Feb 25, 19]
Blackstone Life Sciences, the biopharma investing arm of private equity firm Blackstone Group, has made its first strike. It has joined with Novartis to start a new biotech, Anthos Therapeutics (Cambridge, MA), backed with $250 million in cash and rights to an experimental drug originally discovered by the Swiss firm. [Ben Fidlar, xconomy.com, Feb 27, 19]
Spark Thera up 120% [Feb 25, 19]
Avrobio up 22% [Feb 25, 19]
Akcea Thera up 17% [Feb 25, 19] Novartis [said it] will pay $150 million to license a heart disease medication discovered by Ionis Pharma co-developed by Ionis with its majority-owned subsidiary Akcea Therapeutics. Ionis will get half the money, paid for with Akcea stock.[Bradley Fikes, San Diego Union Tribune, Feb 25, 19]
REGENXBIO up 16% [Feb 25, 19]
immunotherapy startup NexImmune (Gaithersburg, MD; $300K SBIR) reported raising $7.7M in new equity funding.[Kieran McQuilkin, DCInno, Feb 25, 19]
Nuvaira (Minneapolis, MN; no SBIR), developer of therapeutic medical devices for treating certain lung diseases, announced it had closed a $79 million financing round. The capital will be used to support a clinical trial for Nuvaira’s Lung Denervation System, a catheter-based treatment meant as an alternative to drug therapy. [Amanda Ostuni, MinnieInno, Feb 11, 19]
Dexcom, a maker of continuous glucose monitors for people with diabetes, said it will cut 350 full-time jobs in San Diego and Arizona as its shifts some customer support and other functions overseas. [Mike Freeman, San Diego Union Tribune, Feb 22, 19]
Universal Display up 23% [Feb 22, 19] increased its dividend by two-thirds
Liquida Tech up 22% [Feb 22, 19]
Marinus Pharma up 18% [Feb 22, 19]
Aqua Metals up 16% [Feb 22, 19]
Harpoon Thera up 16% [Feb 22, 19]
Karyopharm Thera down 43% [Feb 22, 19] FDA staff raised questions about the therapy’s efficacy and safety. [xconomy.com, Feb 22, 19]
Zosano Pharma down 24% [Feb 22, 19]
Roche (Swiss) agreed to acquire Spark Therapeutics (Philadelphia, PA, no SBIR) for about $4.8 billion. [Wall Street Journal, Feb 25, 19]
Innovation not enough. The fracking industry is struggling to attract investors after nearly a decade of losing money. [Wall Street Journal, Feb 25, 19]
Few law enforcement jobs are more coveted than the FBI’s special agent positions. But the tightest labor market in decades is forcing the bureau to aggressively recruit candidates. [Wall Street Journal, Feb 25,19] Consequences of a sleazy president attacking his own government.
Zosano Pharma (Fremont, CA; no SBIR, founded 2006, IPO 2015) up 171% [Feb 21, 19], a clinical-stage biopharmaceutical company, announced the completion of the second and final goal of the long-term safety study for [proprietary] Qtrypta, in which patients treated migraine attacks over a one year period. The long-term data generated in this trial reinforced the well-tolerated safety profile and strong efficacy results previously reported in the six-month dosing portion of this safety study and in the randomized Phase 2/3 ZOTRIP pivotal study. [company press release, Feb 20, 19] total funding $166M [crunchbase.com]
Four months after Immune Design (no SBIR) halted a late-stage study for its lead cancer vaccine and saw its stock price cut nearly in half, the immunotherapy company is now in line to join Merck’s pipeline in a deal worth approximately $300 million. Merck announced that it has agreed to acquire Immune Design [Frank Vinluan, xconomy.com, Feb 21, 19]
Small-business optimism is down for five straight months and hit a more-than-two-year low in January amid uncertainty about domestic politics and global growth. [Jeff Sparshott, Wall Street Journal, Feb 21, 19]
Everspin Tech up 18% [Feb 20, 19]
Axonics Modulation Technologies (Irving, CA; no SBIR, founded 2012, IPO Nov 2018) up 17% [Feb 20, 19], a medical technology company focused on the development and commercialization of novel implantable Sacral Neuromodulation ("SNM") devices for the treatment of urinary and bowel dysfunction, disclosed today positive top-line results from the ARTISAN-SNM pivotal study, designed to gain marketing approval from the U.S. Food & Drug Administration ("FDA") for the Axonics r-SNM(R) System(1). [company press release, Feb 19, 19] total funding $146M [crunchbase.com]
Galectin Thera up 15% [Feb 20, 19]
Blaze Bioscience (Seattle, WA; no SBIR, founded 2010) Raises $5M to Help Surgeons See Tumors From Healthy Tissue developing “tumor paint” that could help surgeons tell the difference between normal and cancerous tissue [Jeff Buchanan, xconomy.com ,Feb 20, 19] total funding $35M [crunchbase.com]
AstraZeneca retires MedImmune (Gaithersburg, MD; $3.5M SBIR, acquired 2013) brand [Washington Business Journal, Feb 20, 19]
Everspin Tech (Chandler, AZ; $600K SBIR)up 16% [Feb 19, 19] develops and manufactures magnetic RAM or magnetoresistive random-access memory, including stand-alone and embedded MRAM products as well as spin-torque MRAM. [company website]... announces that it commencedshipment of pre-productioncustomer samplesofits 28nm 1-Gigabit(Gb)Spin Torque Transfer Magnetoresistive Random Access Memory (STT-MRAM)product in December 2018.[company press release, Jan 8, 19]
Hoth Therapeutics down 17% [Feb 19, 19]
Danger words. Trump claims "absolute right to .... " declare an emergency despite the clearly framed emergency law that allows Congress to stop such a declaration.
Success. In 2017, Duchenne muscular dystrophy drug maker Sarepta signed a deal with Duke University to research potential cures for the disease using the gene-editing system CRISPR. Now the Duke lab at the center of that research pact is reporting promising results from a trial of CRISPR in mouse models of DMD. [Arlene Weintraub, Fierce Biotech, Feb 18, 19]
Passage Bio (Philadelphia, PA; no SBIR) debuted with a $115.5 million Series A financing ... to develop a portfolio of five therapeutic candidates to treat rare monogenic CNS diseases. These programs are being developed under a research, collaboration and license agreement with the University of Pennsylvania (Penn) and its Gene Therapy Program (GTP) together with the Penn Orphan Disease Center (ODC), with the support of co-founder James M. Wilson, M.D., Ph.D. [company press release, Feb 14, 19]
PureTech’s Vor Biopharma (Boston, MA; no SBIR) raised $42 million in its series A round, which will support the development of its lead asset, an engineered stem cell therapy for acute myeloid leukemia (AML). [Amirah Al Idrus, Fierce Biotech, Feb 14, 19]
Five [DARPA funded] research teams will study the behavior of marine organisms to develop sensors designed to detect and track manned underwater vehicles and drones in strategic waters. [Jane Edwardson, GovConWire, Feb 19, 19] no small biz
In the largest analysis of the issue thus far, investigators have found that the smaller the research team working on a problem, the more likely it was to generate innovative solutions. Large consortiums are still important drivers of progress, but they are best suited to confirming or consolidating novel findings, rather than generating them. The new research [is] published in the journal Nature. .... a trio of investigators led by James A. Evans, a sociologist at the University of Chicago, mined selections from three vast databases: the Web of Science, using more than 42 million articles published since 1950; the United States Patent and Trademark Office, with 5 million patents granted since 1976; and GitHub, with 16 million software projects posted since 2011. [Benedict Carey, NY Times, Feb 13, 19]
Love that
limitless credit card.
It’s no longer cool to
talk about the
federal budget
deficit. President Trump didn't talk about it during his State of the
Union. Neither did Stacey Abrams in her Democratic response. All told,
Washington’s red-ink alarms have gone dead, even though the annual
deficit
will pass the trillion-dollar mark starting in 2022. [Jeff
Sparshott, Wall Street Journal, Feb 19, 19]
The Trump Administration Can’t Get a United Front Against Iran [Defense One, Feb 19, 19] who would trust any Trumpian figure to act in the group's interest?
Hoth Therapeutics (New York, NY; no SBIR, founded 2017) up 25% [Feb 15, 19] developing topical treatments for eczema, raised $7 million from [IPO] [nasdaq.com, Feb 15, 19]
Translate Bio up 27% [Feb 15, 19]
Ablative Solutions (Kalamazoo, MI; no SBIR, founded 2011) medical device company raised a $77 million Series D [Will Flanagan, MinnieInno, Feb 5, 19] offers an alternative to surgical renal denervation for treating hypertension; total prior funding $63M [crunchbase.com]
Soliton (Houston, TX; no SBIR, founded 2012) raised $10M with its IPO; makes a medical device that quickens the tattoo-removal process. [Chris Matthews, Houston Business Journal, Feb 15, 19] prior funding $25M [company website]
Liquidia Tech up 16% [Feb 14, 19]
Caladrius Biosciences [Basking Ridge, NJ; $2M SBIR, founded 2006) down 25% [Feb 14, 19] announced top-line results from The Sanford Project: T-Rex Study, a prospective, randomized, placebo-controlled, double-blind Phase 2a clinical trial [that showed] no improvement in the primary endpoint of preservation of C-peptide levels vs. placebo at 1 year was observed at the group level [company press release, Feb 13, 19] total funding $63M [crunchbase.com]
CryoLife down 15% [Feb 14, 19]
Xeris Pharma down 13% [Feb 14, 19]
FLIR Systems raised its dividend by 6% [Feb 14, 19]
Gemini Bio-Products (West Sacramento, CA; no SBIR) and StemBioSys (San Antonio, TX; no SBIR, founded 2010, total funding $14M [crunchbase]) announce a strategic partnership that will bring StemBioSys’ [develops proprietary stem cell technologies for the regenerative medicine market] entire selection of matrices and cells into the Gemini portfolio. [joint companies press release, Feb 11, 19]
End the ending, prime the pump. Federal Reserve officials are zeroing in on a strategy to end the wind-down of their $4 trillion asset portfolio [Wall Street Journal, Feb 15, 19] national economic mirage relies on government debt boosting by posturing free-market politicians
Arcadia Biosciences up 14% [Feb 13, 19]
XOMA up 14% [Feb 13, 19]
Johnson & Johnson reached a deal to buy medical technology firm Auris Health for about $3.4 billion in cash. J&J said that Auris’s technology will help it develop a digital solution addressing different parts of patients’ lung-cancer treatment. If certain milestones are reached, Auris could also receive as much as $2.35 billion more in the deal. .... [Co-founder] Dr. Frederic Moll is also a co-founder of Intuitive Surgical that makes the da Vinci robotic-assisted surgery system as well as the Ion endoluminal system, designed for lung biopsies. [Allison Prang and Peter Loftus, Wall Street Journal, Feb 13, 19]
CTI BioPharma (Seattle, WA; $200K SBIR) announced that it has received a $10M milestone payment from Teva Pharmaceutical Industries related to the achievement of sales milestones for TRISENOX® (arsenic trioxide). TRISENOX was acquired from CTI BioPharma by Cephalon [which] was subsequently acquired by Teva. [CTI press release, Feb 11, 19]
Linnaeus Therapeutics (Haddonfield, NJ; no SBIR) raised $2.3M [Philadelphia Business Journal, Feb 11, 19] a development stage biotech company engaged in the identification and development of small molecule agents that modulate cellular differentiation for the treatment of cancer and disorders of pigmentation. [company website]
ADMA Biologics (Ramsey, NJ; no SBIR) up 21% [Feb 12, 19] biopharmaceutical and specialty immunoglobulin company that manufactures, markets and develops specialty plasma-derived biologics for the treatment of immune deficiencies and the prevention of certain infectious diseases, announces that it has entered into a senior secured term loan facility for up to $72.5 million. [company press release, Feb 12, 19]
Xeris Pharma (Chicago, IL; $8.7M SBIR, founded 2005) down 21% [Feb 12, 19] announced that it filed a registration [for] a proposed public offering of 5M shares of its common stock [company press release, Feb 11, 19] prior funding $148M [crunchbase.com]
3DEO (Gardena, CA; $1M SBIR, founded 2016), a metal 3D printing company that manufactures parts for medical and other industries, raised $14 million, according to [SEC] filing. [Dana Bartholomew, LA Business Journal, Feb 8, 19]
Neurogene (New York, NY; no SBIR, founded 2018) is breaking into gene therapy with $68.5 million in new funding to support research on experimental treatments for rare, genetic brain disorders, the first of which could start human testing next year. [Frank Vinluan, xconomy,con, Feb 12, 19]
Proteostasis Thera up 22% [Feb 11, 19]
Replimmune up 19% [Feb 11, 19]
CellDex Thera (Hampton, NJ; $600K SBIR) down 19% [Feb 11, 19] after a one-for-fifteen reverse stock split [company press release, Feb 8, 19]
FLIR Systems agreed to purchase Endeavor Robotics (spinout from iRobot, Chelmsford, MA, founded 2016) from Arlington Capital Partners for about $385M in cash to make its entry into the market for unmanned ground vehicles for military, critical infrastructure and public safety applications. ... The transaction came weeks after FLIR acquired Canada-based unmanned aerial systems manufacturer Aeryon Labs for approximately $200M. [Jane Edwards, GovConWire, Feb 11, 19]
Nuvaira (Minneapolis, MN; no SBIR, founded 2008), a developer of novel therapeutic medical devices to treat obstructive lung diseases, announced it has closed a $79 million equity financing. ... the first interventional pulmonary company to pursue and report one-year randomized, double-blinded and sham-controlled clinical evidence in COPD patients from a Phase 2b trial. [company press release, Feb 11, 19] prior funding $69M [crunchbase.com]
A soft future. CB Insights, a firm that tracks start-ups, analyzed a variety of data to create a list of 50 private companies around the world that are on a path to a $1 billion valuation. [Erin Griffith, NY Times, Feb. 10, 19] One of the fifty is doing something to create a new market - in oncology. The rest are mostly software that are almost all certain to work. The only risk is business risk - will it make a profit.
Alpine Immune down 15% [Feb 8, 19]
Gossamer Bio (San Diego, CA; no SBIR, founded 2017) a clinical-stage biopharmaceutical company focused on discovering, acquiring, developing and commercializing therapeutics in the disease areas of immunology, inflammation and oncology, announced its [IPO to raise] $276 million. [company press release, Feb 7, 19] prior funding $330M [crunchbase.com]
Cancer immunotherapy developer Harpoon Therapeutics raising approximately $76 million in [IPO] ... develops immunotherapies that direct the T cells of a patient to target and kill cancer cells. [Frank Vinluan, xconomy.com, Feb 7, 19]
biotech Sirnaomics (Gaithersburg, MD; SBIR) took in another $11 million in investments, following a $25 million raise in mid-2018 led by mainland China and Hong Kong investors. [to] support the company’s oncology and fibrosis clinical programs. [Kieran McQuilkin, DCInno, Feb 7, 19]
iRobot said it paid $8 million in higher tariffs to bring its Chinese-made robots to U.S. markets as a result of the White House’s newly installed trade policies. The company announced it would be moving some production to a manufacturer outside of China for the first time since 2002. [Brian Dowling, xconomy.com, Feb 8, 19]
Enterin (Philadelphia, PA; no SBIR, founded 2016) developing a drug that has the potential to provide a new way to treat Parkinson’s patients, raises $16.7M [John George, Philadelphia Business Journal, Feb 1, 19] prior funding $13M [crunchbase.com]
Trice Medical (Malvern, PA; no SBIR) announced that it is acquiring S.E.G-WAY™ Orthopaedics (Carlsbad, CA; no SBIR), a leader in solutions for minimally invasive orthopedic procedures. SegWAY is best known for its Endoscopic Carpal Tunnel Release (ECTR), a device that supports minimally invasive carpal tunnel surgeries. Trice Medical addresses the growing need for accurate, cost-effective orthopedic diagnostic solutions with its mi-eye™, a fully disposable arthroscopy camera. [Trice press release, Feb 7, 19]
The Army has activated an Artificial Intelligence Task Force on the Carnegie Mellon University campus in Lawrenceville, Pa., that is home to the National Robotics Engineering Center. The university has made many robotic advances, including creating flexible, soft and inflatable robots able to move over rough surfaces. What to watch: The task force is expected to spread to other institutions as the Army searches for cutting-edge advances in robotics and autonomous systems. [Association of the U.S. Army news, Feb 8, 19]
She offers clues, lingering on the nation’s narcissistic impulses, its fights over identity politics and the naivete of thinkers who believed that globalization would break down nationalism rather than intensify it. [Carlos Lozada reviewing Ratner-Rosenhagen's The Ideas That Made America, WashPo, Feb 8, 19]
In the long run, a third or so of the country cannot effectively govern the other two-thirds with an unpopular agenda and a Twitter account. [Jonathan Rauch and Peter Wehner, NYTimes, Feb 8, 19]
Solid Biosciences down 68% [Feb 7, 19] the company has revealed that its SGT-001 candidate achieved low levels of expression of microdystrophin protein at the starting dose in a phase 1/2 trial. Solid Bio says it is working toward escalating the dose used in the trial as soon as it can [Phil Taylor, Fierce Biotech, Feb 7, 19]
Sangamo Thera down 31% [Feb 7, 19] reported preliminary molecular and enzymatic evidence of editing of the human genome in vivo (inside the body). These findings are part of the interim results from the Phase 1/2 CHAMPIONS Study evaluating SB-913, a zinc finger nuclease (ZFN) in vivo genome editing product candidate for the treatment of patients with Mucopolysaccharidosis Type II (MPS II) [company press release, Feb 7, 19]
Xencor (Monrovia, CA; $900K SBIR), a clinical-stage biopharmaceutical company developing engineered monoclonal antibodies for the treatment of autoimmune disease, asthma and allergic disease, and cancer, announced it has entered into a research and license agreement with Genentech, a member of the Roche Group, to develop and commercialize novel IL-15 cytokine therapeutics, including XmAb®24306. XmAb24306 is an IL-15/IL-15Rα cytokine complex engineered with Xencor's bispecific Fc domain and Xtend™ Fc technology and is Xencor's most advanced preclinical cytokine program. ... Genentech will pay Xencor $120 million upfront, and Xencor will be eligible to receive up to $160 million in development milestones for the XmAb24306 program and up to $180 million in development milestones for each new IL-15 drug candidate.[Xencor press release, Feb 5, 19]
Alector (South San Francisco, CA; no SBIR), taking an immunotherapy approach to Alzheimer’s disease and other brain disorders, raised $176 million in an [IPO].[Frank Vinluan, xconomy.com, Feb 6, 19]
Stealth
BioTherapeutics (Newton,
MA; no SBIR, founded 2006) plans
[IPO] to raise $81 million, to help
fund studies of its late-phase asset in multiple indications related to
mitochondria dysfunction. [Conor Hale, Fierce Biotech, Feb
7,
19]
total funding $100M [crunchbase.com]
Trump loves the new NAFTA. Congress doesn’t. and both Democrats and Republicans say it has little chance of passing without significant changes. [Jim Tankersley, New York Times, Feb 7, 19] Trump and any other aspirational leaders must face the reality that the US Constitution gives Congress the ultimate power in any disagreement. There is no binding Treaty until Congress ratifies it. And once ratified, it is the law of the land that the Executive Branch must adninister.
A. Ernest Fitzgerald, a [famous whistle-blowing] Pentagon official tasked with analyzing project expenses died at 92. At one point he noted that any high cost Pentagon system was a bundle of overpriced spare parts flying in close formation. He served in an isolated office, with secretary, from 1970 to 2006. He also cited as Fitzgerald's law that “There are only two phases of a program. The first is, ‘It’s too early to tell.’ The second: ‘It’s too late to stop.’ ” [Harrison Smith, Washington Post, Feb 7, 19]
MacroGenics up 130% [Feb 6, 19] on positive results from Sophia, its late-stage clinical study of the efficacy of margetuximab in patents with HER2-positive metastatic breast cancer. ... said its breast cancer treatment outperformed Roche's (RHHBY) blockbuster Herceptin in a late-stage test. [yahoofinance.com, Feb 6, 19]
XBiotech up 17% [Feb 6, 19]
Immunogen up 14% [Feb 6, 19]
Catabasis Pharma down 24% [Feb 6, 19]
Aeglea BioThera (Austin, TX; no SBIR) down 19% [Feb 6, 19] announced the pricing of an underwritten public offering of of its common stock at $8.00 per share [to] raise $60M [company press release, Feb 6, 19]
Bolt Biotherapeutics (Redwood City, CA; no SBIR, founded 2015) a biotechnology company focused on unleashing the power of the immune system to achieve anti-tumor immunity in patients, announced the completion of a $54M Series B financing [company press release, Feb 5, 19] founded by Ed Engleman, a professor of pathology and medicine at Stanford Medicine. The company’s drug platform is based on technology licensed from Stanford University. [Frank Vinluan, xconomy.com, Feb 5, 19] total funding $30M [crunchbase.com]
JustRight Surgical, now Bolder Surgical (Louisville, CO; no SBIR, founded in 2010), announced it has secured $27 million. ... provides surgeons right-sized surgical instruments to safely and effectively perform minimally invasive surgery in pediatric patients from neonate to teenager. [company press release, Jan 16, 19]
ArcherDX (Boulder, CO; no SBIR, founded 2013) a molecular technology company dedicated to developing breakthrough solutions that advance the application of personalized genomic medicine, is pleased to announce the acquisition of Baby Genes (Golden, CO; no SBIR) focused on empowering individuals to take charge of their health through genetic insights. [ArcherDX press release, Jan 30, 19] total funding $30M [crunchbase.com]
MassDevelopment has issued a $2.4 million Emerging Technology Fund loan to Nano-C (Westwood, MA; $1.3M SBIR, founded 2001), a leading developer of nanostructured carbon for use in electronics and energy applications. Nano-C will use loan proceeds to upgrade its manufacturing facility. [company press release, Jan 16, 19] prior funding $17M [crunchbase.com]
Strella Biotechnology [from University of Pennsylvania] won first prize of $100K for winning the Arizona State University Innovation Open. [Hayley Ringle, Phoenix Business Journal, Feb 6, 19] ... developing a biosensor that can predict the maturity of virtually any fresh fruit. [company website]
“It is not that machines are going to replace chemists. It’s that the chemists who use machines will replace those that don’t.” —Derek Lowe, a longtime drug discovery researcher, tells the New York Times that artificial intelligence techniques will play a growing role within his field. [MIT Tech Rvw, Feb 6, 19]
Amyris (Emeryville, CA; $900K SBIR as Amyris Biotechnologies, founded 2003) up 73% [Feb 5, 19] announced that it has signed a binding term sheet for a planned cannabinoid development, licensing and commercialization partnership valued at up to $255 million (not including significant royalties once the products are commercialized) with a confidential partner. [company press release, Feb 5, 19] total funding $518M [crunchbase.com]
Arcadia Biosciences up 20% [Feb 5, 19]
XBiotech up 16% [Feb 5, 19]
Sustainable Bioproducts (Chicago, IL; $3.6M SBIR) biotech startup making a fermentation process to produce lab-grown protein, announced it has raised $33 million in Series A funding [from] from top investors, including Bill Gates. [Jim Dallke, ChicagoInno, Feb 5, 19] NASA, the National Science Foundation, the National Park Service, the U.S. Environmental Protection Agency (EPA), the U.S. Department of Agriculture (USDA), the State of Montana and Montana State University have provided financial and in-kind support to the company. ... technology emerged out of fundamental research into extremophile organisms that live in Yellowstone National Park’s volcanic springs. [company press release, Feb 4, 19]
Ligand Pharmaceuticals (San Diego, CA; SBIR) announces closing a [$3M] investment in Dianomi Therapeutics (Madison, WI; no SBIR, founded 2017) focused on improving the delivery and efficacy of large and small molecules in the treatment of a variety of diseases and on therapies for inflammatory diseases, such as osteoarthritis and pain. [Ligand press release, Feb 5, 19] Dianomi's proprietary Mineral Coated Microparticle (MCM) technology [was] developed at the University of Wisconsin-Madison, that is uniquely designed to provide stability and controlled release delivery of biologics and small molecule drugs. [Dianomi press release]
argenx (Netherlnds) and Halozyme Therapeutics (San Diego, CA; no SBIR, founded 1998) announced a global collaboration and license agreement that enables use by argenx of Halozyme's ENHANZE® drug delivery technology to develop multiple subcutaneous product formulations for current or future argenx product candidates. The agreement provides argenx exclusive access to ENHANZE® for any product targeting the human neonatal Fc receptor FcRn, including argenx's lead asset efgartigimod (ARGX-113) and up to two additional targets, potentially shortening drug administration time, reducing healthcare practitioner time, and offering additional flexibility and convenience for patients. argenx will pay an upfront payment of $30 million to Halozyme, $10 million per target for future target nominations and potential future payments of up to $160 million per selected target subject to achievement of specified development, regulatory and sales-based milestones. Halozyme will also receive mid-single digit royalties on sales of commercialized products. [joint companies press release, Feb 4, 19] total funding $200M [crunchbase.com]
Money does not spend itself. A new study released by the Senior Executives Association paints a dire picture of the federal workforce, one that is stretched too thin, hampered by old technology and the target of partisan attacks. Without a significant overhaul, agencies may fail to provide adequate services when they are needed most, the researchers found. [Erich Wagner, Government Executive, February 5, 2019] Since 1960, 15% more employees and 400% more money to be spent. Polticians love to demand more from government while shrinking it and its pay rate.
Organogenesis down 14% [Feb 4, 19]
Monteris Medical (Plymouth, MN; no SBIR, founded 1999) which makes tumor-destroying laser technology, has secured $10.7 million of the $17 million of [planned] equity financing [Alex Wittenberg, Minneapolis / St. Paul Business Journal, Jan 28, 19] prior funding $132M [crunchbase.com]
Infinera up 17% [Feb 1, 19] announced the expansion of its portfolio of metro packet-optical solutions with the introduction of the Infinera 7100 PSX-3S platform. The compact, high-density 1 rack unit (1RU) 7100 PSX-3S platform enables cost-effective access and aggregation of diverse metro traffic types, including high-speed Ethernet and 10 gigabits per second (Gb/s) and 100 Gb/s wavelength-division multiplexing (WDM). [company press release, Jan 30, 19]
II-VI up 14% [Jan 31, 19] reported good earnings
EM Photonics (Newark, DE; $29M SBIR) agreed to pay $2.75 million to resolve claims that it defrauded the Navy, Air Force, NASA, and other federal agencies, according to a statement from the U.S. Department of Justice. received about $18 million in contracts for the U.S. Army, Navy and Air Force, among other federal agencies. .... develops complex algorithms for modeling various physical conditions in fluid dynamics, structural mechanics, and electromagnetic fields [Josephine Peterson and Karl Baker, Delaware News Journal, Jan 30, 19]
Cullinan Oncology (Cambridge, MA; no SBIR) and The Wistar Institute (Philadelphia, PA) announced an agreement to accelerate the development of VK-2019, a novel EBNA1 (Epstein-Barr Nuclear Antigen 1) inhibitor discovered by The Wistar Institute. [joint press release, Jan 30, 19] total funding $150M [crunchbase.com]
Alpine Immune Sciences (Seattle, WA; no SBIR) a leading immunotherapy company dedicated to developing innovative treatments for patients suffering from cancer and autoimmune/inflammatory diseases, announced it has entered into a definitive securities purchase of common stock expected to result in gross proceeds of $25 million [company press release, Jan 16, 19]
Startup Act reintroduced, would expand federal innovation support. Senators Jerry Moran (R-Kan.) and Mark Warner (D-Va.), co-signed by Senators Roy Blunt (R-Mo.) and Amy Klobuchar (D-Minn.), re-introduced the Startup Act today. The bill would enact an array of innovation policies, including reauthorizing Regional Innovation Strategies, creating a new commercialization grant program, and implementing a startup visa. SSTI has endorsed the bill and hopes to see the legislation passed by the 116th Congress. Read more. Sounds good to politcians, BUT, who would fund it, run it, and on what criteria?
Dewpoint Therapeutics (Cambridge, MA and Dresden, Germany; no SBIR, founded 2018), translating the emerging area of biomolecular condensates into drug discovery, launched with a $60 million Series A. ... is harnessing recent insights into biomolecular condensates elucidated by founders Anthony Hyman of the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden and Richard Young of the Whitehead Institute with the goal to uncover treatments for the toughest diseases. Biomolecular condensates have long been known but historically understudied because they are difficult to analyze with traditional drug discovery methods like protein crystallography and biochemical activity assays. [company press release, Jan 30, 19]
OncoCyte (once a subsidiary of BioTime, Alameda, CA; no SBIR, founded 2009), a developer of novel, non-invasive tests for the early detection of cancer, announced positive results from its key R&D Validation study demonstrating the accuracy of the Company’s DetermaVu™ liquid biopsy test for lung cancer. The R&D Validation study demonstrated a sensitivity of 90% (95% CI 82%-95%) and specificity of 75% (95% CI 68%-81%) of DetermaVu™ on a prospectively collected cohort of 250 patient blood samples that were blinded to laboratory operators. [company press release, Jan 30, 19]
Miracle cancelled.. [Taiwan] Electronics giant Foxconn reversed course and announced that the huge Wisconsin plant that was supposed to bring a bounty of blue-collar factory jobs back to the Midwest — and was lured with billions in tax incentives — will instead be primarily a research and development center staffed by scientists and engineers [for college graduates]..... company originally planned to build high-tech liquid crystal display screens in a project President Donald Trump had proudly pointed to as a sign of a resurgence in American manufacturing. ... because the [2017] global market environment has shifted. [AP, Jan 30, 19]
"They are wrong! Perhaps Intelligence should go back to school!" [Twitter-in-Chief]. Sen. Mark R. Warner (D-Va.), the vice chair of the Senate Intelligence Committee, also weighed in. “The President has a dangerous habit of undermining the intelligence community to fit his alternate reality. People risk their lives for the intelligence he just tosses aside on Twitter.” [WashPo, Jan 31, 19]
Voyager Therapeutics (Cambridge, MA; no SBIR) up 38% [Jan 29, 19] cut a deal with Neurocrine Biosciences (San Diego, CA) to bankroll the [development] journey—and forfeit some of the financial upside for the product known as VY-AADC [for] $115 million in cash and buying $50 million worth of the company’s shares. [Ben Fidler, xconomy.com, Jan 29, 19]
Zynerba Pharma up 25% [Jan 29, 19]
Lyndra Therapeutics [Watertown, MA; no SBIR, founded 2015), which is moving toward making daily pills a thing of the past, today announced it has raised $55 million in Series B financing, funds it will use for Phase II clinical trials, expansion of its Phase I pipeline and manufacturing scale-up. [company press release, Jan 29, 19] prior funding $84M [crunchbase.com]
Arbor Biosciences ((acquired two weeks ago by Chiral Technologies (part of DAICEL CORPORATION, West Chester, PA)), Ann Arbor, MI; no SBIR) focused on next-generation-sequencing target enrichment and synthetic biology, has a new partnership with the International Wheat Genome Sequencing Consortium, an organization developing a “gold-standard reference genome for bread wheat,” Arbor said in a press release. The partnership will focus on the Chinese Spring variety of wheat. [Sarah Schmid Stevenson, xconomy.com, Jan 29, 19]
Born to lead? Mary C. Daly was a high-school dropout in a small town outside St. Louis who believed her best option in life was to become a bus driver. ... Today Daly, 56, is president of the Federal Reserve Bank of San Francisco, making her one of the most powerful shapers of economic policy in the United States. [Heather Long, Washington Post, Jan 27, 19]
Einstein said. ‘For knowledge is limited, whereas imagination embraces the entire world, stimulating progress, giving birth to evolution.’ [quoted by Steven Shapin reviewing Pimental's The Rhinoceros and the Megatherium, London Review of Books, March 2019]
Fantasy exposed, again. “A large majority of respondents—84%—indicate that one year after its passage, the 2017 Tax Cuts and Jobs Act has not caused their firms to change hiring or investment plans,” said Kevin Swift, president of NABE and chief economist at the American Chemistry Council. [Yuval Rosenberg and Michael Rainey, Fiscal Times, Jan 29, 19] Trickle-down benefits of tax cuts for the wealthy remain a fantasy.
FLIR Systems (Wilsonville, OR, $1.6M SBIR, founded 1978) announced that it has acquired Aeryon Labs (Canada), a leading developer of high-performance unmanned aerial systems (UAS) for the global military, public safety, and critical infrastructure markets for $200 million. Aeryon’s vertical takeoff and landing quad-copter airframes integrate multiple sensors, including FLIR thermal technology, to provide users with immediate high-resolution intelligence, surveillance, and reconnaissance (ISR) capability. [company press release, Jan 28, 19]
ArcherDX (Boulder, CO; no SBIR, founded 2013), a molecular technology company dedicated to developing breakthrough solutions that advance the application of personalized genomic medicine, announced that [FDA] granted a Breakthrough Device designation (formerly Expedited Access Pathway program) for ArcherDx’s companion diagnostic assay application. [company press release, Jan 9, 19] total funding $35M [crunchbase.com]
Not as many new companies have been forming since 2000 — for reasons that experts don’t totally understand — and existing companies have been expanding at a slower rate. (The pace of job cuts has also fallen, which is why the unemployment rate has stayed low.) Rather than starting new projects, companies are sitting on big piles of cash or distributing it to their shareholders. ... Over all, though, the generational gap in both income and wealth is growing. [David Leonhardt, NY Times, Jan 28, 19]
A changed world. The sum of US imports and exports as a percentage of GDP nearly doubled from 1986, when this ratio was 16.9 percent, to 30.9 percent in 2013, only to decline slightly to 26.5 percent in 2016 (based on data from the World Development Indicators of the World Bank at https://data.worldbank.org/indicator/NE.TRD.GNFS.ZS?locations=US). [Joel Slemrod, J Economic Perspectives, Fall 2018]
Mersana Thera down 17% [Jan 25, 19]
Talee Bio (Philadelphia, PA; $400K SBIR) a development stage biopharmaceutical focused on developing gene therapy treatments for cystic fibrosis, announced agreements with the Cystic Fibrosis Foundation (CF Foundation) to fund the preclinical development of two mutation-agnostic gene therapy product candidates, TL-101 and TL-102. The CF Foundation committed up to $4.5 million to expedite the development of both product candidates for all people with cystic fibrosis, and particularly those individuals with no viable treatment options for the underlying cause of the disease. [company press release, Jan 23, 19]
DayZero Diagnostics (Boston, MA; no SBIR, founded 2016) an infectious disease diagnostic company using genome sequencing and machine learning to enable rapid and precise treatment in an era of growing antibiotic resistance, announced the completion of a $8.6M Series A round. .... developing a sequencing-based rapid diagnostic that identifies, within hours, both the species and the antibiotic resistance profile of a bacterial pathogen. [company press release, Jan 23 19] prior funding $12M [crunchbase.com]
Pharma giant AbbVie reported that The latest quarter included a charge of $4.1 billion to reflect the diminished value of AbbVie’s 2016 acquisition of Stemcentrx (no SBIR), whose experimental cancer drug fared poorly in clinical testing. AbbVie previously had big sales expectations for the drug. [AbbVie press release, Jan 24, 19] In 2015 Stemcentryx had raised $500 million and is valued at $3 billion, people familiar with its finances say, a nearly unprecedented value for a company with no revenue, facing the usual R&D obstacles, and that almost no one has heard of. [previously reported, Antonio Regalado, technologyreview.com, September 8, 2015]
Vertex Pharma has regained limited rights to two DNA-dependent protein kinase (DNA-PK) inhibitors from Merck KGaA. Merck licensed the drugs and other assets for $230 million upfront two years ago but has now granted Vertex the right to use them in certain gene-editing applications. [Nick Paul Taylor, Fierce Biotech, Jan 23, 19]
Johnson & Johnson is eyeing robotic surgery maven Auris Health, and plans to purchase it above its $2 billion valuation, according to reports. [Conor Hale, Fierce Biotech, Jan 23, 19]
Attune Pharmaceuticals (New York, NY; ?? SBIR, founded 2018) focused on the discovery and development of novel, orally-administered, small molecule therapeutics for the treatment of rare diseases, announced the completion of a $23 million Series B financing [to] to advance Attune’s pipeline, which includes the ongoing clinical development of ATN-249, a novel orally-administered plasma kallikrein inhibitor for the treatment of Hereditary Angioedema (HAE). HAE is a rare genetic condition that causes episodic, potentially life-threatening swellings that can affect any part of the body. [company press release, Jan 23, 19]
For the third time, the FDA has halted testing of an experimental cervical cancer therapy from Advaxis, axalimogene filolisbac. The stoppage is related to manufacturing problems, not safety issues, according to the Princeton, NJ-based firm, which also lost a partnership with Amgen last month. [Alex Lash, xconomy.com, Jan 25, 19]
The stock price of Editas Medicine sank nearly 20 percent after CEO Katrine Bosley announced without warning she will leave in March. The news comes as Editas prepares to start its first clinical test: An experimental gene-editing therapy for an inherited form of blindness. [Alex Lash, xconomy.com, Jan 25, 19]
at the annual meeting of the National Tax Association in November 2017, one of the keynote speakers began his remarks by asserting that if one set a monkey in front of a typewriter and, after some period, saved only those parts of what had been typed having to do with tax reform, the resulting tax law would be better than what the Republicans were poised to legislate. The speaker was Harvard economist and former Secretary of the Treasury Lawrence Summers. [Joel Slemrod, J Economic Perspectives, Fall 2018] Taxation always suffers from the political fantasy that what the present power group wants would be good for everybody. One-year economic returrns say that the critics were right.
Tell us that tale again. Trump advisers lied again and again, Mueller says. The question is, why? [WashPo, Jan 27, 19] Let's consult our mirrors for the culprit as we insist our politicians and the media tell us what we want to hear. That tax cuts will boost everyone's economic health, that a concrte wall will stop narcotics, opiods, and hard-working immigrants. And the internet lets us choose our own supporters and echo chambers.
An early prototype of Boeing’s self-driving air taxi completed its first flight, marking what could be an early breakthrough in the company’s vision for autonomous, on-demand flight. The aircraft successfully took off, hovered and landed, all of which employed its autonomous navigation and landing systems, according to a [compamy] release... The test marks an early milestone for Boeing’s Aurora Flight Sciences (Manassas, VA; $25M SBIR) subsidiary, which it acquired in 2017 for a sum that wasn’t disclosed. [Aaron Gregg, WashPo, Jan 23, 19]
Plenty of capital. Over the six-year period from 2013 to 2018, as total venture capital investments nearly tripled, growing from $47.5 billion in 2013 to nearly $131 billion in 2014, the number of deals increased by just 13.5 percent according to new data from the NVCA-PitchBook Venture Capital Monitor. The $131 billion in total VC investments in 2018 is the largest amount since PitchBook began tracking the data in 2006 and the first year since the height of the dot-com boom that annual capital investment eclipsed $100 billion. [SSTI, Jan 23, 19] The idea that small biz needs SBIR, because there is too little money being invested in innovation, looks silly when viewed thru a VC lens, especially when government agencies have autonomy to fund whatever they want.
New data from the U.S. Chamber of Commerce suggests the extended government shutdown is having a significant adverse effect on 41,000 small businesses across all 50 states. Small government contractors have lost $2.3 billion in revenue thus far 34 days into the shutdown, with another $29 billion at risk if the shutdown continues, Neil Bradley, executive vice president and chief policy officer at the U.S. Chamber of Commerce, told reporters. [Frank Konkel, NextGov, Jan 24, 19] Small biz thinking about who has responsible attitude for election 2020?
Trump fore-runners. Conflict of Inerest. George Washington was a stockholder when the [Bank of England] was financing the war to put down his rebellion. ..... Ready, fire, aim. The charismatic Montague Norman, is attributed with a large role in the development of the ‘“mystique” of the central banker’. He hated experts, and preferred to make decisions by instinct, turning to economists not to tell him what to do, but to supply explanations for things he had already done. [Jamie Martin reviewing David Kynaston's history of the Bank, LondonRB, Jan 24, 19]
Microbot Medical (Hingham, MA; no SBIR) up 21% [Jan 23, 19] announced $2.5M new funding ... [recently] demonstrated an activated Self-Cleaning Shunt (SCS(TM) ) The Company's SCS(TM) was activated from a working prototype of its customized headset that is intended to be used periodically by either the patient or the healthcare provider for the operation of the SCS(TM). [press release, Jan 17, 19]
Oculogica (New York NY; no SBIR, founded 2013), a pioneer in algorithm-based neuro-diagnostics, announced that [FDA] granted their De Novo request for the commercialization of EyeBOX®, the first non-invasive, baseline-free tool to aid in the diagnosis of concussion. Oculogica plans to market the device for use in pediatrics ages 5 and older and adults up to 67 years of age, starting with a pilot launch for select, qualified sites. [company press release, Jan 3, 19] total funding $7M [crunchbase.com]
Gossamer Bio (San Diego, CA; no SBIR, founded 2017), a clinical-stage biopharmaceutical company focused on therapeutics in the disease areas of immunology, inflammation and oncology, announced a proposed [$230 million] IPO. [company press release, Jan 23, 19] total funding $330M [crunchbase.com]
Translate Bio (Lexington, MA; no SBIR), a clinical-stage messenger RNA (mRNA) therapeutics company developing a new class of potentially transformative medicines to treat diseases caused by protein or gene dysfunction, announced that the Company has received verbal notification from [FDA] that the Agency has completed its review of the Company’s Investigational New Drug Application (IND) submission for MRT5201 for the treatment of ornithine transcarbamylase (OTC) deficiency and has additional clinical and nonclinical questions. ... The FDA is placing the IND on clinical hold until [certain] questions are resolved.[company press release, Jan 23, 19]
Generex Biotechnology (Miramar, FL and Canada; no SBIR), an integrated healthcare holding company [company website], completes $15M acquisition of Regentys. [South Florida Business Journal, Jan 7, 19]
Altimmune up 16% [Jan 22, 19]
Organogenesis down 29% [Jan 22, 19]
Editas Medicine down 20% [Jan 22, 19]
Cocrystal Pharma down 16% [Jan 22, 19]
Although we may think we have the most sophisticated understanding of finance than anyone before us, the recurrence of financial crises and other financial problems over time, as demonstrated in this book, suggests that we could use some history lessons. [Yongseok Shin reviewing William N. Goetzmann’s Money Changes Everything: How Finance Made Civilization Possible, J Economic Literature, Dec 2018]
Russia Says He’s a Spy. His Lawyer Says He Just Wanted Photos of a Cathedral. [New York Times, Jan 23, 19] Rule: avoid places without rule of law, or you could become a trading asset. .
Eden no more. Sir David Attenborough [long time naturalist] has warned that “the Garden of Eden is no more”, as he urged political and business leaders from around the world to make a renewed push to tackle climate change before the damage is irreparable. [Grahame Wearden, The Guardian, Jan 22, 19] as Greenland’s enormous ice sheet is melting at such an accelerated rate [more than 400 billion tons per year] that it may have reached a “tipping point,” and could become a major factor in sea-level rise around the world within two decades, scientists said in a study [just] published .[John Schwartz, New York Times, Jan 21, 19]
Organogenesis down 45% [Jan 18, 19]
Immunomedics down 26% [Jan 18, 19] announced it has received a Complete Response Letter (CRL) from [FDA] for the Biologics License Application (BLA) seeking accelerated approval of sacituzumab govitecan for the treatment of patients with metastatic triple-negative breast cancer (mTNBC) who have received at least two prior therapies for metastatic disease. [company press release, Jan 17, 19]
ALung Technologies raises $5M [Patty Tascarella, Pittsburgh Business Times, Jan 9, 19]
More proteins for DNA. Dr Romesberg and his colleagues have been encouraging their new, “semisynthetic” cells to use the expanded alphabet to make proteins that could not previously have existed, and which might have properties that are both novel and useful. Now they think they have found one. In collaboration with a spin-off firm Synthorx (LaJolla, CA; no SBIR, founded 2014), they hope to create a less toxic and more effective version of a cancer drug called interleukin-2. [The Economist, Jan 18,19] total funding $79M [crunchbase.com]
The Pentagon’s out-there-thinking department, DARPA, is working on autonomous attack swarms more like a murmuration of starlings than a formation of fighter-bombers. What human operators could co-ordinate such dynamics? [The Economist, Jan 18, 19] Note: DARPA is required by law to put 3% of its external contracts into SBIR, and looks for novelty; why not for you, out-there-thinker with swarm control ideas.
Trumponomics disappoint. The tax-cut steroid wore off within six months of its passage. Corporate investment rose at a 10% annual rate in the first half of 2018 but then slowed to 2.5% in the third quarter. According to the Institute for Supply Management, new orders for manufacturing equipment plunged 11 points in December. The logical explanation is that corporations won’t invest unless they expect an adequate return on such investments. That return depends on there being enough buyers for the goods and services they produce. But there aren’t enough. [Robert Reich, The Guardian, Jan 18, 19] No matter: Trump's base doesn't read eonomics, they just applaud his atmospherics.
Organogenesis down 60% [Jan 17, 19]
DARPA has awarded Exquadrum (Adelanto, CA; 48 SBIRs) and Dynetics (Huntsville, AL; 32 SBIRs) a contract to develop technology for hypersonic weapons. Called the Operational Fires (OpFires) Propulsion System program, "the program aims to develop and demonstrate a novel ground-launched system for hypersonic boost glide weapons to penetrate modern enemy air defenses and rapidly and precisely engage critical time sensitive targets," the companies said in a joint statement. [DefenseOne, Jan 17, 19]
there has never been a better example of the unforeseen benefits of pure research because no one guessed that a technique of such power and universality would emerge from what appeared to be a fascinating but arcane corner of biology [Peter Forbes reviewing A Crack in Creation by Jennifer Doudna and Samuel Sternberg].
Lessons Learned. The Army published a study of the U.S. war in Iraq that criticizes decisions of some of the service’s most senior officers and outlines hard-learned lessons from the conflict. [Wall Street Journal, Jan 17, 19] The Army believes in learning lessons from its adventures.
The [SBA] has stopped approving routine small-business loans because of the shutdown. The result: Business owners are halting plans for expansion and repairs, and considering costlier sources of cash, Ruth Simon reports. [Jeff Sparshott, Wall Street Journal, Jan 17, 19]
Re-launch the viewgraphs, and now power-points. the new[Trump announced] missile-defense strategy rests most of its hopes on other technologies that essentially do not exist, and may never do so. The review says, for example, that the F-35 Joint Strike Fighter could be networked with new sensors and outfitted with new missiles to take out adversary missiles on the launch pad. Tests have shown that the F-35 can do this. But the jet has to be in the enemy’s airspace already. [Patrick Tucker, DefenseOne, Jan 17, 19] We have added defense with the Trump reality show.
by being so brazen and uncooperative during its rise, China has actually activated the antibodies that will help prevent its success. [Kori Schake, in her book Safe Passage, 2017] a lesson to be recognized about the Trump adninstration, if not within
Lipstick for the pig. U.S. officials are debating ratcheting back tariffs on Chinese imports as a way to calm markets and give Beijing an incentive to make deeper concessions in a trade battle that has rattled global economies. [Wall Street Journal, Jan 17, 19] Expect such a concession to be touted as one step back to take two steps forward.
Vaccinex (Rochester, NY; $4.5M SBIR) up 21% [Jan 16, 19] announced today that it has completed subject enrollment for the SIGNAL trial. SIGNAL is a Phase 2, multi-center, randomized, double-blind, placebo controlled study in subjects with early manifest and late prodromal Huntington's disease (HD) to assess the safety, tolerability, pharmacokinetics, and efficacy of VX15/2503 (pepinemab). [company press release, Jan 16, 19] total funding $12M [crunchbase.com]
Cerecor up 16% [Jan 16, 19]
Aptinyx down 66% [Jan 16, 19] reported that NYX-2925 did not achieve statistically significant separation from placebo on primary endpoint [company press release, Jan 16, 19]
Ligand Pharma down 16% [Jan 16, 19]
Krystal Biotech (Pittburgh, PA; no SBIR) ), a gene therapy company developing topical and intradermal "off-the-shelf" treatments for rare dermatological diseases, today announces that construction of Ancoris, a new state-of-the-art Good Manufacturing Practice (GMP) facility, is complete. The new facility is located near the Company’s headquarters in Pittsburgh and will support clinical and commercial manufacturing of Krystal’s lead product candidate, KB103, for the treatment of dystrophic epidermolysis bullosa (DEB). The facility will be officially open in 1Q 2019 following completion of the first engineering run. [company press release, Jan 15, 19] total funding $7M plus IPO $45M [crunchbase.com]
FUJIFILM Cellular Dynamics (Madison, WI), a leading developer and manufacturer of human induced pluripotent stem cells (iPSCs) and tissue-specific cells differentiated from iPSCs, has announced the launch of its newest product, iCell® Microglia. Microglia are the immune cells of the central nervous system responsible for fundamental physiological and pathological processes. Differentiated from human iPSCs, iCell Microglia will be used in life science research to enable the study and development of therapies for degenerative neurological diseases such as Alzheimer’s disease. [company press release, Jan 8, 19]
Five Prime Therapeutics is cutting its headcount by 20 percent, part of a cash-saving effort the company is making to focus on the cancer drugs it has already advanced into clinical trials. ... Five Prime also has an alliance with Bristol-Myers Squibb, which paid the biotech $350 million up front in 2015. The most advanced program in the alliance, cabiralizumab, is an antibody drug that blocks a protein called colony-stimulating factor-1. The drug is now in two Phase 2 studies in pancreatic cancer. [Frank Vinluan, xconomy.com, Jan 15, 19]
If not evidence, what? We're pleased to release a new evidence report as part of our Straight Talk on Evidence initiative. The report—"FDR’s call for 'bold, persistent experimentation': An antidote to 40-year stagnation in key areas of social policy (part two in a series)"—is posted on the Straight Talk website. Straight Talk on Evidence is an initiative of the Laura and John Arnold Foundation's (LJAF) Evidence-Based Policy team. [Jon Baron, VP of Evidence-Based Policy, Laura and John Arnold Foundation] Jon was a House staffer on SBIR and then an imaginative head of DOD's SBIR office in the Clinton Years.
What price glory, for a Wall? Federal contractors can’t count on receiving any compensation for lost labor. With nine of the 15 major federal agencies unfunded, some federal contractors and their employees are taking drastic measures to try to stay afloat. Low- and middle-wage workers are looking for new jobs, small- and medium-size firms have stopped paying employees and may have to fire some people, and the financial institutions that support those companies are assuming greater risk, Andrew Duehren reports. “How long can it go on? We’re counting the days until we’re out of business.” —Gary Shumaker, president and CEO of C2 Solutions Group. ... President [glory-seeking] Trump's top economic adviser said the broader impact of the shutdown remains fairly limited [Jeff Sparshott, Wall Street Journal, Jan 15, 19] The President doesn't need his salary, and his staff dare not speak truth.
Proteostasis Thera down 15% [Jan 14, 19]
Cree announces that it signed a multi-year agreement to produce and supply its Wolfspeed® silicon carbide (SiC) wafers to STMicroelectronics, a global semiconductor leader serving customers across the spectrum of electronics applications. The agreement governs the supply of a quarter billion dollars of Cree’s advanced 150mm silicon carbide bare and epitaxial wafers to STMicroelectronics (Swiss) during this period of extraordinary growth and demand for silicon carbide power devices. [company press release, Jan 7, 19]
biotech Sirnaomics (Gaithersburg, MD, $1.2M SBIR, founded 2007) has taken in another $11M in investments, following a $25M raise in mid-2018 led by mainland China and Hong Kong investors. ... to support the company’s oncology and fibrosis clinical programs. Read more from Washington Business Journal. [DCInno, Jan 14, 19]
Autolus Therapeutics (England) said it plans to create up to 170 jobs at its new U.S. headquarters and manufacturing facility in Rockville MD over the next three years and invest about $28 million in Shady Grove Life Sciences Center. .. will get a boost from a $200,000 Economic Development Fund conditional grant from the county, while the state of Maryland is providing a $525,000 "Advantage Maryland" conditional loan. [Washington Business Journal, Jan 14, 19]
Xencor (Monrovia, CA, $900K SBIR, founded 1997), a clinical-stage biopharmaceutical company developing engineered monoclonal antibodies for the treatment of autoimmune disease, asthma and allergic disease and cancer, today announced it will regain rights to develop and commercialize XmAb13676, a CD20 x CD3 bispecific antibody, from Novartis effective June 20, 2019, due to strategic pipeline reprioritization by Novartis. [company press release, Jan 14, 19] total funding $108M [crunchbase.com]
Apollomics (previously CBT Pharmaceuticals, Foster City, CA and China), an innovative biopharmaceutical company committed to the discovery and development of oncology combination therapies, announced that it has raised $100 million in a Series B financing., Foster City and China), an innovative biopharmaceutical company committed to the discovery and development of oncology combination therapies, announced that it has raised $100 million in a Series B financing. [company press release, Jan 14, 19]
PQ Bypass (Sunnyvale, CA; no SBIR, founded 2009) has gathered $60 million in equity financing to move forward with its minimally invasive technology for treating long blockages in leg arteries caused by peripheral artery disease. [company press release, Jan 8, 19] prior funding $10M [crunchbase.com]
Locus Biosciences (Research Triangle Park, NC; no SBIR) developing precision antibacterial therapies, announced it has entered into an exclusive collaboration and license agreement with Janssen Pharmaceuticals to develop, manufacture and commercialize CRISPR-Cas3-enhanced bacteriophage ("crPhage™") products targeting two key bacterial pathogens for the potential treatment of infections of the respiratory tract and other organ systems. .. Locus will receive $20 million in initial payments, and is eligible to receive up to a total of $798 million in potential future development and commercial milestone payments, and royalties on any product sales. [company press release, Jan 3, 19]
Black Diamond Therapeutics (Cambridge, MA and Switzerland) developing next-generation precision medicines for cancer, announced the completion of an oversubscribed Series B financing of $85 million [to] accelerate the development of Black Diamond’s pipeline and to expand its mutation, allostery and pharmacology (MAP) computational and discovery platform for identifying and targeting allosteric oncogenic mutations [company press release, Jan 10, 19]
Beta Bionics (Boston, MA, no SBIR, founded 2105) a medical technology company leveraging lifelong, machine-learning, artificial intelligence to develop and commercialize the world’s first autonomous bionic pancreas – announced that the company has now completed its Series B equity financing, which has reached a total of $63 million. [company press release, Jan 8, 19]
Boston Metal (Woburn MA; no SBIR) announced that it has raised $20M in a Series A funding round led by Breakthrough Energy Ventures with participation from Prelude Ventures and The Engine [which] accelerates the first industrial-scale deployments of Boston Metal’s molten oxide electrolysis (MOE) technology for the production of ferroalloys. The new funding also supports the continued scale-up of MOE for the production of emissions-free steel.... invented at the lab-scale at MIT and Boston Metal has since scaled the technology over 1,000x. [company press release, Jan 10, 19] Venture Breakhrough is $1-billion Bill Gates-chaired. The idea sounds a lot like a derivative of an earlier MIT spinout Molten Metal advoacated by the then MIT Tech spin-out leader John Preston.
OSSIO (Woburn, MA; no SBIR), an orthopedic fixation company, announced that its OSSIOfiber™ Bone Pin Family has received 510(k) market clearance from the U.S. Food and Drug Administration (FDA). This first of its kind technology features a proprietary bio-integrative material to provide stability and secure bone fixation during the healing process, leaving no permanent hardware behind. [company press release, Jan 7, 19]
Massachusetts startups raised $12B across 660 deals in 2018. Some notable ones include Cambridge Telematics (software Cambridge, MA; no SBIR) $500M, and Relay Therapeutics (Cambridge, MA; no SBIR) [at the intersection of computation and biotechnology] [company website], $400M. [Srividya (Sri) Kalyanaraman, BostInno, Jan 11, 19]
James P. Allison, once an outsider from the small Texas town of Alice, who went on to discover how T cells could be programmed to fight cancerous tumors. ... a basic science researcher happy to be wrong 99 times to be right once.” ... the fact that Allison won the Nobel Prize in Physiology or Medicine this past October assures immunotherapy its rightful place in the fight against cancer. [Mimi Swartz reviewing Graeber's THE BREAKTHROUGH Immunotherapy and the Race to Cure Cancer, NY Times, Jan 12, 19]
Generative adversarial networks (GANs) are the hottest neural network technique around. But they could also give us insight into how AI algorithms “think,” writes Karen Hao. ... Researchers fed a GAN various photos of scenery—trees, grass, buildings, and sky. They found that, over time, it learned to organize the pixels into sensible groups without being explicitly told how [MIT Tech Rvw, Jan 10, 19]
Modern science depends on money, institutions and oodles of brainpower. Partly because its government can marshal all three, China is hurtling up the rankings of scientific achievement. An analysis of 17.2m papers in 2013-18, by Nikkei, a Japanese publisher, and Elsevier, a scientific publisher, found that more came from China than from any other country in 23 of the 30 busiest fields, such as sodium-ion batteries and neuron-activation analysis. [The Economist, Jan 12,19]
Yesterday's Solution.The Trump administration is readying guidance that could let states remodel their Medicaid programs to more closely resemble block grant proposals, according to people familiar with the discussions. [Wall Street Journal, Jan 12, 19] Republicans love to propose block grants that would transform the idea of a United States into the original idea of confederation of states. The people who hate the federal income tax seek the same backwalk without admitting the reality that led to federal direct taxation. Perhaps SBIR could also evolve from a national competition to a formal fair-share program. Why all this talk: today's problem was yesterday's solution.
Discussion. Trump's Day: The president meets with state and community leaders at the White House this afternoon to discuss border security. [Jerry Seib, WSJ, Jan 11, 19] Look for the conventional Army idea: If I want your opinion, I'll tell you what it is.
Ben succeeds, state cuts funding An independent economic analysis of the Ben Franklin Technology Partners reveals its impact on Pennsylvania’s economy — boosting the overall economy by $4.1 billion between 2012 and 2016, helping to create 11,407 high-paying jobs and generating $385 million in tax receipts for the state. Because the jobs were created in industries that pay 52 percent higher than the average nonfarm salary in Pennsylvania, the impact on the state’s GSP was greater, according to the report. However, such impact is threatened by decreasing state funding in the program, [which] has dropped more than 50 percent since 2007-08. [SSTI, Jan 19, 19]
Organogenesis (Canton, MA; two SBIRs) up 513% [Jan 9, 19] re-cleared for market listing
Axsome Thera down 15% [Jan 9, 19]
AVROBIO down 17% [Jan 8, 19]
Intact Vascular (Wayne, PA; no SBIR, founded 2011), a developer of medical devices for minimally invasive peripheral vascular procedures, today announced the first commercial use of its Tack Endovascular System® in multiple hospitals within Germany. A novel therapy for dissection repair following balloon angioplasty, the Tack® implant is a first-of-its kind device for patients with peripheral arterial disease (PAD) and/or critical limb ischemia (CLI). [company press release, Jan 8, 19] total funding $90M [crunchbase.com]
Banner Life Sciences LLC (High Point, NC; no SBIR, founded 1999) specialty pharmaceutical company, announced that [FDA] granted tentative approval on November 16, 2018 of the Company’s New Drug Application for BAFIERTAM, ™ a novel fumarate bioequivalent alternative to a prodrug of BAFIERTAM , Tecfidera ® (dimethyl fumarate) of Biogen, Inc. , as treatment for patients with relapsing forms of multiple sclerosis [company press release, Jan 2, 19]
Small-capitalization companies are projected to notch another year of big profit gains, potentially making their shares a haven for investors as earnings at larger firms slow. Analysts are expecting firms in the Russell 2000 index of small-capitalization companies collectively to post double-digit profit gains throughout 2019, according to financial-data provider Refinitiv, far outpacing the S&P 500. Russell 2000 companies tend to have market capitalizations of $300 million to $2 billion. [Michael Wursthorn, Wall Street Journal, Jan 8, 19] Professional guess-work in a fluid world.
La meme chose. Although he had little understanding of the challenges, he parlayed a line of blather into a seat at the table. Before long, there was a proposal..... No, no, not a Wall in 2016; a nineteenth century railroad .... to build a Pan-American Railway, backed by governmental subsidies. [Charkes Morris reviewing Rutkow's The Longest Line on the Map, Wall Street Journal, Jan 8, 19] Le plus ca change, la meme chose.
Shutdown for SBIR. The Greenwoods have useful advice for SBIR hopefuls during federal shutdown at www.g-jgreenwood.com.
Axsome Therapeutics New York, NY; no SBIR, founded 2012) up 161% [Jan 7, 19] a clinical-stage biopharmaceutical company developing novel therapies for the management of central nervous system (CNS) disorders, today announced that AXS-05, a novel, oral, investigational NMDA receptor antagonist with multimodal activity, met the prespecified primary endpoint and significantly improved symptoms of depression in the ASCEND Phase 2 trial in major depressive disorder (MDD). .... also announced that today it raised approximately $23.3 million through the sale of [common] shares. [company press release, Jan 7, 19] total funding $7M [crunchbase.com]
Exact Sciences up 15% [Jan 7, 19]
Axogen down 23% [Jan 7, 19] provided a business update, including preliminary unaudited fourth quarter and full year 2018 results [company press release, Jan 7, 19]
Alector (South San Franciso, CA; $1.5M SBIR, founded 2013) filed to go public [forr $150M] to fund human tests of its experimental therapies for degenerative brain disorders such as Alzheimer’s disease. [xconomy.com, Jan 7, 19] thas raised total of $194.5M in funding over 5 rounds [company website]
Frequency Therapeutics (Woburn, MA; no SBIR, founded 2015) reeled in $42 million in a Series B round for its hearing loss drugs. ... expects to release data this year from its first clinical trial, which is testing a drug injected into the ear to spur growth of sensory cells. [Frank Vinluan, xconomy.com, Jan 7, 19] total funding $76M [crunchbase.com]
Keros Therapeutics (Lexington, MA; no SBIR) raised $23 million in Series B financing, which will help the startup move two drugs for rare neuromuscular diseases through to mid-stage clinical testing. [Frank Vinluan, xconomy.com, Jan 7, 19] prior funding $11M [crunchbase.com]
Apic Bio (Cambridge, MA; no SBIR, founded 2017) receiving $40 million in Series A financing. The -based startup is working on gene therapies for a genetic form of ALS, and a rare lung and liver disease called Alpha-1. [Frank Vinluan, xconomy.com, Jan 7, 19] prior funding $11M [crunchbase.com]
Eight months after gene sequencing company10x Genomics (Pleasanton, CA; SBIR) raised $125 million in debt and equity financing, the company now has an additional infusion of cash. ... announced that the equity portion of last year’s funding, a $50 million Series D round, has been extended by $35 million. [Frank Vinluan, xconomy.com, Jan 7,19]
Cancer drug developer Stelexis Therapeutics (New York, NY; no SBIR, founded 2017) announced that it closed a $43 million Series A financing to expand its proprietary platform to discover and selectively target pre-cancerous stem cells. [company press release, Jan 7. 19]
Got/need security clearance during shutdown? finances continue to top the reasons for security clearance denial and revocation. ... security clearance holders do have good reasons to be concerned that financial hardships brought about by the shutdown could affect their security clearance. [Lindy Kyzer, govexec.com, January 7, 2019] Taking heart because you trust The Donald to act in your best interest?
Thousands of federal contractors are already feeling the pinch. According to Bloomberg’s Christopher Flavelle and Paul Murphy, contractors could see more than $200 million per day in lost or delayed revenue due to the shutdown. Not all contractors are suffering equally, though, since they vary considerably in size and include defense giants such as Boeing and General Dynamics that can more readily weather the storm. [Fiscal Times, Jan 7, 19] Note that funded agencies, like DOD, have the money to pay the contractors.
[L]et me beat any unreformed supply-siders to the punch on one final topic: There is little or no evidence that the Tax Cuts and Jobs Act of 2017 had much of an impact on wages — and certainly workers haven’t seen the absurd $4,000 per employee windfall President Donald Trump’s economic advisers and political allies made before the tax cut was passed by Congress. [Barry Ritholtz, Fiscal Times, Jan 7, 19]
Epizyme up 33% [Jan 4, 19]
Sienna Biopharmaceuticals up 26% [Jan 4, 19] to Present at Dermatology Summit [company press release, Jan 4, 19]
Suro Biopharma up 22% [Jan 4, 19]
Idera Pharma up 17% [Jan 4, 19]
Catalyst Biosciences up 15% [Jan 4, 19]
Esperion Therapeutics(Ann Arbor, MI; no SBIR) announced that they have entered into a licensing agreement with Daiichi Sankyo Europe (DSE) providing DSE with exclusive rights to commercialize bempedoic acid and the bempedoic acid / ezetimibe combination pill in the European Economic Area and Switzerland. The agreement combines Esperion Therapeutics’ first-in-class ATP Citrate Lyase (ACL) inhibitor, bempedoic acid, with Daiichi Sankyo’s European commercial capabilities which includes more than 1000 professionals dedicated to the commercialization of cardiovascular (CV) products, as well as synergies with their existing portfolio of novel oral anticoagulant and antiplatelet products ... Esperion to Receive $300 Million in Upfront and Near-term Milestones – – Up to $900 Million in Total Milestones [company press release, Jan 4, 19]
Poseida Therapeutics (San Diego, CA; no SBIR) filed for [IPO] to raise up to $115 million, .... working on a form of personalized immunotherapy for the treatment of cancer called CAR-T, or chimeric antigen receptor T cell therapy, with hopes to address some the current limitations of current CAR-T therapies. [MarketWatch, Jan 4, 19]
Locus Biosciences (Morrisville, NC; no SBIR) a developer of precision antibacterial therapies, has signed an exclusive collaboration and license agreement with Janssen Pharmaceuticals, one of the Janssen Pharmaceutical Companies of Johnson & Johnson. The deal could be worth up to $818 million. The companies will team up to develop, manufacture and commercialize a product targeting a key bacterial pathogen for the potential treatment of infections of the respiratory tract and other organ systems. [ncbiotech, Jan 4, 19]
Cabaletta Bio, a cell therapy startup spun out of the University of Pennsylvania, raised a $50 million Series B. [Frank Vinluan, xconomy.com, Jan 4. 19]
Immusoft (Seattle, WA; $300K SBIR, founded 2009) developing technology to genetically reprogram patients’ B cells outside the body to produce therapeutic proteins, said it raised $20 million from investors. [Jeff Buchanan, xconomy.com, Jan 4, 19] prior funding $12M [crunchbase.com]
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BMDO/ MDA including SBIR the doings of star wars
Miscellaneous Stories 1996-1997; 1998-1999; 2000-2001; 2002-2003 ; 2004-5 ; 2006; 2007 2009-2010 ; 2011-2012; 2013-2014; 2015; 2016; 2017
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Note: in these old stories, many links are dead, obsolete, or missing
Stories about companies; 1-Al .. Am-Az .. B .. C ... D-E .. F .. G-H .. I-J .. K-L .. M ... N-O ... P ... Q-R .. S1-Se .. ... Sf-Sz .. T-U .... V-Z
10X Genomics ..... 1366
Technologies ... 1st Detect ...
21-Century Silicon ... 21st Century
Systems .... 23andMe ... 24M Technologies
... 30
Second Software ... 360fly ..... 3Bar Biologics .... 3C Semiconductor
... 3D Glass Solutions ..... 3Dnamics ..... 3D
Robotics .... 3D Systems
..... 3D Technology
Laboratories
.... 3F ... 3iNanotech .... 3PrimiR ...
3Scan ..... 3-V
Biosciences
.... 3VR ... 410 Medical Innovation .... 454 Life Sciences .... 4C
Medical Technologies .... 4D Molecular Therapeutics ..... 4s3
Bioscience ... 5D Robotics
..... 7AC
Technologies ... 89Bio ... 908Devices ... 9Mile Labs
A10 Networks ... A123Systems ... A&G
Pharmaceutical ... Aastrom
Bioscience
.. Abacus Technology ... ... Abaxis .... Abcombi Sciences
.....
Abeona Therapeutics
..... AbGenomicsInternational
... Abiomed ... Ablexis
...... ABL
Technologies .... Abpro
Therapeutics ..... AbSci .... Absorbent
Materials ... Abundant Robotics ..... AbVitro ...
Acadia Pharma ... Acambis
.. Accel Diagnostics ..... Acceleron Pharma
... Accelrys
... Accentia
BioPharmaceuticals ... Accent Therapeutics ..... Accera ....
Access Pharmaceuticals
...
Access
Scientific .... Accion Systems ..... Accumetrics
... AccuraGen ..... Accurate
Automation
.. Accuray ... Accuri Cytometers
... Acelerox ....
Acelity .... AcelRx
Pharmaceuticals ...
Acera Surgical ....
Acetylon
Pharmaceuticals ... Achaogen ... Achates
Power .....
Achillion
Pharmaceuticals ... ACIST Medical Systems .... Acorda
Therapeutics
... Acorn
Cardiovascular ... Acquia .... AcroMetrix
... AcryMed ...
ActaCell ... Actasys .... ACT Biotech ... Active
Power ...
ActivBiotics
... ActivMedia Robotics .... Acton Pharmaceuticals
...
Actuality... Acucela ... AcuFocus ....
Aculight
...
Acumentrics ... AcuraStem .... Acutus Medical .... Adamas
Pharmaceuticals ......
Adamis Pharmaceuticals
... Adapteva .... Adaptimmune Therapeutics .... Adaptive
Biotechnologies ..... Adaptive
Computing
... Adaptive
Phage Therapeutics ..... Adaptive TCR ... Adarza BioSystems
.....
Addiction
Therapeutix
...
Addrenex Pharmaceuticals ... Adelor ... Adenosine
Therapeutics
... Adesto Technologies .... Adeza Technologies ... Adherex
Technologies ... Adhesys Medical .... Adial Pharmaceuticals .... Adicet
Bio .... AdiMab
... ADispell ... Adlyfe .... Admittance
Technologies
.... Admune Therapeutics ..... Adnexus
Therapeutics ... Adrenergics .... Advanced
BioHealing ... ADS Biotechnology ... Aduro BioTech
.... Advanced Animal Diagnostics .... Advanced Biologics ..... Advanced
Bionics
... Advanced Cell Diagnostics ... Advanced Cell
Technology (now sub to Bio-Techne) ... Advanced Ceramics
.... Advanced
Circulatory .....
Advanced Countermeasures
Systems ... Advanced Diamond
Technologies .... Advanced Electron Beams ...
Advanced Fuel
Research ...Advanced Life Sciences ... Advanced Lighting
Technologies ... Advanced Liquid Logic
...
Advanced Magnetics ... Advanced Photonix ....
Advanced
Programming Concepts ... Advanced Receiver
Technologies .... Advanced Scientific Concepts ..... Advanced Targeting
Systems
.... Advanced
Technology
Materials.(ATMI) ... Advanced Uro-Solutions ..... AdvanDx ...
Advantic ..... Advaxis ..... Adventrx
... Adverum Biotechnologies ..... Advion BioSciences
...
Adynxx ...... Aegea
Medical ... Aegerion Pharmaceuticals .... Aeglea
BioTherapeutics
Holdings ..... Aerial BioPharma .... Aerie
Pharmaceuticals
... Aerin Medical ..... AerisPhotonics ...... Aerius
Photonics
... Aerodyne Research ... Aero Farms System
... Aerovel ..... AeroVironment ... Aerpio
Therapeutics .... AesRX
...
AETC ... Aethlon Medical
... Aethon .... Aevi Genomic Medicine .....
Affectiva
.... Afferent
Pharmaceuticals ..... Affigen .... Affinimark
Technologies
... Affinity BioReagents ... Affinium
Pharmaceuticals ..... Affinivax .... Affomix ....
Affymax ....Affymetrix ... aFraxis ... AgBiome ..... AgeneBio
....
Agennix ... Agenovir ..... Agenus .... Agere
Pharmaceuticals ..... Agile
Materials
... Agile
Planet ... AgileSwitch .... Agile Therapeutics ....
Agility
Robotics ..... Agilis Biotherapeutics .... Agiltron...Agilvax ....
Agilyx ....
Aagios
Pharmaceuticals... AgraQuest .... Agritope... Agrivida
... Agro Biosciences .... Aguila
Technologies.....Ahura Scientific.... Aiko Biotechnology
... Aileron Therapeutics .... Aimmune Therapeutics
(formerly
Allergen Research) ..... airtricity... Airware .... Airxpanders ....
Airway Therapeutics .... ait laboratories... Akadeum Life Sciences ....
Akamai
Physics
Akarna
Therapeutics
..... Akashi Therapeutics ..... Akcea Therapeutics ..... Akebia ....
Akero Therapeutics ... Akermin ..... Akers BioScience ..... Akita
Innovations
... Akouos ....
Akrevia Thera .... Akron
Polymer Systems ..... Akron Surface
Technologies ..... Akros Medical ....
Alabama
Cryogenics ... Alafair Biosciences .... Albany Molecular
(AMRI) ...A?
nanotech .... Alcon .... Alcresta
.... Aldagen
... Aldatu Biosciences ..... Aldea
Pharmaceuticals
... .
Alder biopharma Aldevon ..... Aldeyra Therapeutics (formerly
Aldexa Therapeutics) .... Alector .... Alexar Therapeutics .....
Alexion
... ....Alexza ....
Alfalight.... Algaeventure Systems ... Algenetix .... Algeternal
.... Algorithmia ..... Alien Technology
.... Alimera sciences.... Alios BioPharma ....Aliva
biopharmaceuticals ..... AliveGen .... Alivio Therapeutics .....
Alkermes...
Alkeus Pharmaceuticals ...
Allakos ... Allcast ....
Allegro Diagnostics ....
Allegro
microsystems ... Allena Pharmaceuticals .... Allergy Amulet
.....
Allerquest
.... Alleviant Medical .... Allied BioScience ..... Allied Minds ....
Alliqua .... Allos
Alloy Polymers .... Alloy
Surfaces .....
Allurion Technologies ... Allylix ... Alnara Pharmaceutical
...
Alnylam... Alper Biotech ... Alphabet Energy .... AlphaCore Pharma ...
Alphamed.... Alphatec
Holdings .....
Alphavax ... Alpine Biosciences .... Alpine Data
Labs .... Alpine Immune Sciences ..... Alseres ....
Algeternal
.... Alta Devices ... AltAir Fuels ... Altair
Therapeutics
... Altamira Technologies .... AltaRock
... AltheaDX .... Althea
Technologies ... Altimmune ..... Altor ...
Altra ...
Altura Medical ... Altus Pharmaceuticals ...
ALung
Technologies
... Alvine Pharmaceuticals .... Alzeca
..... AMAG
Pharmaceuticals
... Alzheon ..... Amaranth Medical .... Ambarella .....
Amberwave
... Ambiq
Micro ....
Ambit
Biosciences .... AMBP
Technology ... Ambri .... Ambrx ...
Ambry .... Ambys Medicines .... Amendia .... American Bionics .....
American
Gene Technologies International .... American Lithium Energy ....
American Medical Systems ....
American Science and Engineering
... America Stem Cell, now Targagyme .... American
Superconductor
... American XTAL .. Ames
Technology ... Amgen ... Amicus Therapeutics .... Amionx ..... Amnis
...
AMO
Pharma ..... Ampio Pharmaceuticals ..... Ampla
Pharmaceuticals ... Amplimmune .... Amplyx Pharmaceuticals
.....
Amprius .... ARMO
BioSciences
.... Amylin
Pharmaceuticals
... Amylyx ..... Amyris
Biotechnologies ... Anacor Pharmaceuticals ...
Anadys
Pharmaceuticals ... Anakim Biologics ....
Analog Computing
Solutions .... Analytical Space ..... AnaptysBio
... Anavex Life Sciences .... Anchor Therapeutics ...
Ancora Pharmaceuticals
... AnDAPT ..... Anexon .... Anew Optics ... Angeion ...
AngioDynamics
... Angiologix ... Angstrom Medica .... Angstron
Materials
... Animalgesic Labs .... ANI Pharmaceuticals ...
Animetrics .... Anivax .... Anivive Therapeutics ..... Annexon
Bioscience ..... ANP Technologies
..... Ansoft
... Ansun Biopharma (formerly NexBio) .... Antegrin
Therapeutics
..... Anthera
Pharmaceuticals ....
Antigenics ... Anue Systems ... Anulex Technologies
... Anybots ... AOBiome Therapeutics
(formerly
Nitrocell) .... AOptix Technologies
... Aortica ..... APA
Optics (Enterprises) ... Apellis Pharmaceuticals
.....
Apexigen ... Aperion
Biologics
.... Aphios
...
Apieron ... Apnex Medical ... ApniCure .....
ApoCell ....
ApoGen Biotechnologies .... Apollo
Diamond
... Apollo Endosurgery ... Apoplogic
Pharmaceuticals
... Applied Biomolecular Technologies .... Applied Biosystems
.... Applied Defense Solutions ..... Applied Genetic Technology ...
Applied Nanotech ....
Applied
NanoWorks ... Applied Optimization ..... Applied
Optoelectronics ... Applied Physical Electronics ...
Applied Physical Sciences ... Applied Precision ..... Applied
Proteomics ..... Applied Quantum Technologies .... Applied Quantum
Technology
.... Applied Research Associates
... Applied
Science and Technology ... Applied Signal
Technology
... AppThwack .... Aprecia Pharmaceuticals ....
Apricus
Biosciences
... APS BioGroup .... Apse .... Aptalis Pharma .... Aptevo
Therapeutics .....
Aptima ... AptamiR
Therapeutics .... Aptinyx .... Aptose
Biosciences .... Aptus
Endosystems ... Aquaback Technologies ...
Aqua Bounty
... Aquacue .... AquaHarmonics ..... Aqua Metals .... AquaMost
...
Aquarius
Technologies ... Aquestive Therapeutics ....
AqueSys
... Aqueti .... Aquion .... Aradigm ....
AragonPharmaceuticals
...
Aratana
Therapeutics ..... Arbor BiotechnologieArbor Pharmaceuticals
...
Arbovax
... Arbutus BioPharma (formerly OnCore) ..... Arca Biopharma ....
Arcadia Biosciences ..... Arcadia Pharma ..... Arcantatura...
Archemix
... ArcherDX ......Arch Innotek ..... Arch Therapeutics
... Arctic Sand Technologies .... Arcturus Therapeutics ....
Arcus Biosciences ..... Ardea Biosciences ...
Ardelyx .... Ardian .... Arena Pharmaceuticals
... Argentum ..... Arginetix
... Argo AI ..... ArgonST ... Argos Therapeutics ... Aria CV
...
Ariad Pharmaceuticals .. Ariosa Diagnostics ..... Arista MD
....
Arista Networks .... ARIZ Precision
Medicine .... Arkis BioSciences ....... Arkansas Power Electronics
.....
Armadillo Aerospace
... Armetheon .... ARMO BioSciences .... Armonica
Technologies .... Armorworks
... Armune BioScience ..... Aro Biotherapeutics
.... Aronora ..... Arpeggi
.... ArQule ... Arrakis Therapeutics .....
Array ... Array Information Technology ..... Arresto
Biosciences .... Arrien Pharmaceuticals ... Arrivo
BioVentures ..... Arrowhead Pharmaceuticals ..... Arrowhead
Research .... Arsanis ... Arsenal Medical
.... Arstasis ... Artel .... Arteriocyte
... Arterys
..... ArthroCare
...
Arthrosurface ... Artisan Pharma ... Artrility Medical .....
Arvegenix ..... Arvinas .... Arxan Technologies .... Aryx
Therapeutics ..... Aryx
... Arzeda
... Asana Medical (now Regentsys) .... Asante Solutions .....
Ascelegen
Therapeutics .... Ascension
Orthopedics ... Ascent
Solar Technologies ....
Ascent
Therapeutics .... AsclepiX Therapeutics .... Aseptia .... Ash
Access Technology ....
AstroWatt .... Aspen Aerogels .... AspenBio
Pharma .... Aspen Products Group ....
Aspen
Technology
... Aspyrian Therapeutics .... Assurex Health ..... Astex
Therapeutics ...
Asthmapolis
.... Astralux
... Astrobotic Technology ....
Astronautics Corp. of
America ... AstroPower... AstroTerra ..
Astrum Solar ... Astute
Medical ....
Astute Medicales ... Asuragen
... Atacama ..... Atara Biotherapeutics ..... Ataxion ....
Athenex
(formerly
Kinex) ..... Athenix
... Athens Research ..... AtheroGenics ... AtheroMed ....
Athersys .... ATI Industrial
Automation
... Atlantia ... Atmocean .....
Atmospheric Glow
Technologies ...
Atomate ... Atomic Medical Innovations .....
Atomometrics
... Atomwise ..... Atoptix .... Atossa
Genetics
... Atreaon ....
Atreon Orthopedics
..... AtriCure ... Atrium
Medical ... ATRP Solutions ... aTyr Pharma .....
Audentes
Therapeutics ..... Audience
... Augmenix
.... AUM
Cardiovascular ... Aura Biosciences ....
Auris Health .... Auris Medical .... Auris Surgical Robotics
..... Aurora
Algae ... Aurora Flight
Sciences ....
Aurora
Imaging Technology ...
Aurora Spectral Technologies
... Auspex
Pharmaceuticals ... Ausra ... Auterra
.... AuthenTec
....
Automated Dynamics ...
Automated
Medical Instruments .... Autonet ... Aushon
Biosystems
... AutoGenomics .... Autonomic Materials
.... Autonomic Technologies ..... Autonomous Technologies
....
Auxilium
Pharmaceuticals ... Avalanche
Biotechnologies ....
Avanir Pharmaceuticals
... Avant Immunotherapeutics ... Avanti Metal ...
Avaxia
Biologics ... Avedro ... Avelas Biosciences ....
Aveo
Pharmaceuticals
... Avery Therapeutics ..... AveXis .... Aviation Resources
Delaware .... AVI
BioPharma ... Avici Systems ... AvidBiotics
.....Avidity
Biosciences .... Avid
Radiopharmaceuticals
... Avila Therapeutics ... Avinger ....
... Aviragen Therapeutics (formerly Biota
Pharmaceuticals)
..... Aviron ..... Avita Medical Americas ..... Avitude .... Avrobio
..... AVT Simulation .... Aware ... Axcella Health (was Pronutria)
.....
Axelo .... Axerion Therapeutics
... Axial
Biotech .... Axial Biotherapeutics ..... Axion BioSystems
.....
Axion Power
... Axis Clinicals .... Axis
Semiconductor
... Axium Nanofibers ...... Axium Pharmaceuticals .... Axogen
.... Axonia Medical ....Axonics Modulation Technologies
Axsun
Technologies ... Ayasdi ..... Azaya
Therapeutics ... Azelon Pharmaceutical ... Azimuth
.... Aziyo Biologics ..... Azure Biotech ..... AzurRx BioPharma
Bacterial Robotics .... BacterioScan .... Baebies
..... Bagaveev
.... Ballard
Power ... Bamboo Therapeutics ..... Bandgap ... Banyan Biomarkers ...
Bardy
Diagnostics .... BarioSurg ..... Baryonyx .... Barrier
Therapeutics ... Baseload Renewables .... Basis
Science
.... Bastion
Technologies
.... Batu Biologics ..... Bauhaus Software ..... Baxano ...
Baxano Surgical .... BayoTech ..... Beacon Biomedical ..... Beacon
Power ... Beam Therapeutics ..... Beat
Biotherapeutics .... Beeco
... Behavioral Recognition Systems .... Bellicum
Pharmaceuticals .... Belmont Instrument ....
Benchmark
Automation ... BeneChill
... Benefuel ... BeneVir Biopharm ....
Bennett
Aerospace .... Benson Hill
Biosystems ..... Benvenue
Medical .... Berg .... BerrieHill
Research
... BESS Technologies .... BetaBatt
...
BetaLED ....
LEDBG Medicine
... Bettergy .... Bexion Pharmaceuticals .... Bina
Technologies .... Bind
Bioscience ... Bind Therapeutics .... BinOptics ..... BiO2
Medical
... BiO2
Technologies
...
BioAmber ... BioAdvanTek ... BioAffinity
Technologies .....
Bioanalytical Systems
... BioBehavioral Diagnostics ... BioBridge
Global
..... BioCardia .....
BioCentra Molecular Innovations ..... Biocept
...
BioChemics ..... BioClin Therapeutics .... Bicycle Therapeutics .....
Bien-Etre
Labs ..... Bioconnect Systems .... BioConsortia ..... BioCritica
... BioCryst Pharmaceuticals ...
BioDelivery Sciences ... Biodesix .... BioDirection ..... BioDtech
..... BioE ...
BioFire .... BioFluidica ..... Biogenic
Reagents
.... BioGreenChoice ... BioHaven Pharmaceuticals ..... Bioheart
...
Biohelix ... Bio-Imaging Technologies
...
Bioincept .... BioKier ..... Biolex Therapeutics
... BioLife4D ..... BioLink Life
Sciences
... Biolinq (formerly Electrozyme) ,,,, Biologics
...
BioMagnetic Solutions ....
BioMarin
Pharmaceutical
... BioMarck
Pharmaceuticals .... bioMASON ..... Biomatrica ...
BioMedical
Enterprises
... Biomedical Sciences ..... Biomedical
Structures ...
BioMedix .... Biomeme .... Biometric
Signature
... BioMimetic Therapeutics
... BioMotiv .... BioNano
Genomics ... BioNanomatrix ... Bionostics
Holdings
... Bio-Path Holdings ..... Biophan Technologies
... Biophysical ... BioProcessors ...
Bioptigen
... Bioptix .... BiOptix Diagnostics ..... BioPulping
International
...
Biopure ... Biorasis ..... BioRelix ... BioResource
International
...
BioRestorative Therapies (formerly Stem Cell Assurance) ....
BioSante Pharmaceuticals ... BioScale
.... BioSense
Technologies ... BioSensics .... BioSentinel
Pharmaceuticals
... BioSig Technologies ..... Biosortia Pharmaceuticals ....
BioSphere Medical
.... Biostage (formerly Harvard Apparatus
Regenerative
Technology) ..... BioStructures .... Biosurfaces .... Biosym
Technologies later Accelrys
....
BioSystem
...
Biota Pharmaceuticals .... Bio-Techne ..... BioTechnique ....
BioTechPlex .....
Biotectix
....
Biotel
.... BioTelemetry (formerly CardioNet) ..... BioTex
....
Biothera
... BioTheranostics ... Bio Time ...
Biotix
... Biotronic NeuroNetwork ..... Biotronik ....
BioTrove
... BioVaxys .... Bioventus ..... Biovest International ....
BioVex
... BioVirtua ..... Bird Rock Bio (formerly RuiYi) .....
Birich
Technologies .... Biscayne Neurotherapeutics ..... Bitstream
... Black-I Robotics
... Black Sand ... BlackThorn
..... BladeLogic
... Blasch Precision Ceramics .... Blaze
Bioscience ... Blend
Therapeutics ....
BL Healthcare ... Block Engineering ...
Bloom Energy
... Bloo Solar ..... BluDiagnostics ..... Blue Belt
Technologies
...
Bluebird
bio ...
BluDiagnostics .... Bluefin Robotics ... Bluegrass
Proteins
.... Bluegrass
Vascular
Technologies .... Blueprint
Medicines ...
BlueRock Therapeutics ..... Blue
Sky Batteries ... Bluewater Bio International ... Bolt Threads ....
Boom Supersonic ..... Boragen .... Boston Biochem
... Boston Biomedical ... Boston Dynamics
...
Boston Engineering ... Boston Micromachines ... Boston
Micromachines (formally Boston
Electrometallurgical .... Boston-Power
...
Boston
Therapeutics ... Bot Dolly .... Boundless ... BoXZY
..... Braeburn Pharmaceuticals ..... BrainCells
... BrainScope .... Brain Sentry ....
Brain Tunnelgenix
Technologies .... BrainXell ..... Branch Medical Group ..... Brayton
Energy
.... Breathe
Technologies ... Breethe .... Breonics ...
BreviTest
Technologies
..... Brewer
Science ... Bridger Photonics .... Bridgelux
... Brightsource Energy ... Bright View
...
Brimrose Corp of America ... Briteseed .... Brock Rogers Surgical
...
Bromium
.... Brooks
Automation ...
Bruker Daltonics .... Buffalo BioLabs ..... Burl
Concepts
..... Burr Oak
C12 Energy ... C2Sense .... C3Nano
... C4 Therapeutics .... C8
Sciences ....
C9 ... Cabaletta Bio .... CABG Medical ....
Cadence Pharma ....
CadheRx
Therapeutics
.....
Caisson Biotech .... Calabazas
Creek
Research .... Caladrius
Bioscience ... Cala Health ..... Calando
Pharmaceuticals
... Calbiotech .... Calera ... Caliber Biotherapeutics ....
Calibra
Medical ... Calient ... California Wave Power
Technologies ..... Calimmune ..... Caliper Life Sciences
....
CaliSolar ... Calistoga Pharmaceuticals ...
Calithera
BioSciences .... Calixa
Therapeutics ... Callidus Biopharma ... Calporta
Therapeutics
.... Calspan .... Caltech Metals ... Calysta .... Calyxt .....
Cambridge
Endoscopic Devices ... Cambridge Heart
.... Cambridge
Research & Instrumentation ... Cambrios
Technologies .... CAMX ..... Candela Laser ....
Cancer
Genetics .... Cancer Prevention
Pharmaceuticals .... CanDiag .... Canopy Biosciences ..... Capesym
... Capillary
Biomedical ..... Capio Biosciences .... Capnia
... CAPP Medical ..... Capricor Therapeutics .... Cara
Therapeutics .... Carbon .....
Carbon
Design
Systems ... Carbtex Technology
.... Carbylan Therapeutics ..... Cardeas
Pharma ....
CardiacAssist ..... Cardiac Concepts ...
Cardiac
Dimensions
... Cardiac Science ..... Cardialen ..... CardiAQ Valve
Technologies ... Cardica
... CardioDx
... CardioFocus ... CardioInsight Technologies .....
Cardiokinetix ..... CardioMag ... CardioMEMS .... Cardionomic ....
CardioNXT ..... Cardiorobotics
...
Cardiosolutions ... Cardiosolv .... CardioSpectra ... CardioTech
... Cardiovate ..... CardiOx ...
Cardioxyl
Pharmaceuticals
.... CareDx (formerly XDx) .... Caribou Biosciences
.....
Carigent Therapeutics .... Carisma Thera (formerly CARMA Therapeutics)
..... Carmot Therapeutics
..... Carnegie Robotics
.... Carnegie Speech
... .... Carnot BioSciences .... CaroGen .... Carter Aviation
Technologies
.... Carticept
Medical ... Cartiva ..... Cascade Designs ...
Cascade
Microtech
... Cascadian Therapeutics (formerly Oncothyreon) ..... Casma
Therapeutics .... Castle
Biosciences ..... Catabasis Pharmaceuticals
... Catadon
Systems ... Catalyst Biosciences ... Catalytic
Innovations ..... Catalyze ..... Catelectric
.... Cebix .... Cedarburg Pharmaceuticals .... Cedilla
Therapeutics ..... CeeTox
... Celadon ... Celator Pharmaceuticals
... CelcuityCeldara Medical ..... Celladon .... Cellara .... Cell Care
Therapeutics ..... Cellceutix
.... CellCyte
Genetics ... Cell Design Labs ..... Celldex Therapeutics
... ..... Cellectar ... Cellerant
Therapeutics
... Celleration .... Cell Genesys ... CellRight
Technologies
..... Cellular
Bioengineering
...
... Cellular Bioengineering ..... Cellular Biomedicine Group
.....
Cellular Dynamics International .... Cell>Point
.... CellSavers ..... Cellscape .... Cellscript
..... Cell
Signaling Technology ...Cell
Therapeutics (now CTI
BioPharma)
... CellTraffix ... CeloNova Biosciences
..... Cel-Sci
.... Celsion ...
Celtaxsys ..... Celula..... Celularity ..... CellzDirect ...
Cempra Pharmaceuticals.
.... CeNeRx
BioPharma ... Centocor .... Centrexion Therapeutics .....
Centrose ... Centice
...
Centritec
Seals ... Cephalon
... Cepheid
... Cephalon ... Ception Therapeutics
... Cequent
Pharmaceuticals ... Cerebras Systems ..... Ceradyne ...
Ceramitron
... Cerapedics
.... Ceramatec
... Cerevast Therapeutics .... Cerealus Holdings
... Cerecor .... Ceregene ...
Cerahelix
.. Ceres Nanosciences ..... Cerexa .... Cerion
Enterprises ...
Cermet ... Cernostics ..... Cerulean Pharma
... Cerus ... Cervel Neurotech .... Cesca
Therapeutics
....
Ceterix
Orthopaedics ... CFD Research ..
CFX Battery
.... CGI Pharmaceuticals ... ChaCha
... Chantilly BioPharma .... Chapman
Innovations ... Charles River Analytics .... Charles
River
Lab ... Charter Medical ..... Chase Therapeutics .... CHASM
.... Chatham
Therapeutics .....
Checkerspot ..... Chemat
... Chembio Diagnostic
Systems .... ChemImage ... Chemir Analytical
Services ...
ChemoCentryx
... Chemtura ....
Chesapeake Sciences
...Chesson Labs ... Chiasma .... Chimera
Bioengineering ..... Chimerix
... Chlorogen ... Choice Therapeutics
... Chondrogenics
... Chordia
Therapeutics .... Chorum Technologies
.... ChromaCode
..... ChromaDex
..... Chronix
Biomedical
... Chrysalis BioTherapeutics .... Cibus
Global
... Cidara Therapeutics .... Ciena
....Ciencia ...
Cilion .... CimaBay Thera ..... CinRx .... Ciranova
... Circle
Technologies ..... Cirius Therapeutics ..... CivaTech
Oncology
.... CiVi Biopharma ..... Civitas Therapeutics
..... Claret Medical .... Clarassance ..... Claresta
Solutions
.... Clark-MXR ...Claros
Diagnostics
.... Clean Diesel
Technologies ... Clear Catheter Systems .... ClearCount
Medical
Solutions .... ClearEdge
Power .... Clear Guide Medical .... Clearside
Biomedical ... Cleave Biosciences ... Cleveland BioLabs ...
Cleveland
Polymer Technologies ..... CleverSet ... Clinical Data
... Cloudant ... CloudMade ... Cloud
Pharmaceuticals
(formerly Teradiscoveries) .... Clovis
Oncology ... Clovis Tech ..... CMC Biologics .... C-Motive Technologies
.... CoAdna,Holdings ..... CoAxia ....
Cobalt
Biofuels
...
Cocrystal Discovery ... Codexis
... Codiak BioSciences ..... Codon
Devices ... Co-D Therapeutics .... Cofactor
Genomics ....
Cogenra .... Cogentix Medical ..... Cognex
...Cognition
Therapeutics .... Cognitive Code
... Cohera
Medical .... Coherus Biosciences .... Cohesive
Technologies ... ColdQuanta .... ColdWatt ... Collagenex
Pharmaceuticals ...
Collegium Pharmaceutical ... CoLucid Pharmaceuticals
... Columbia Labs ..... CombiMatrix ...
CombinatoRx
..... Combined Energies .... Combinent
BioMedical Systems ... Comfort Motion Technologies
...
Commonwealth Biotechnologies ... Commonwealth
Fusion Systems ..... Compact Membrane Systems ...Compass
Therapeutics .... Compellent Technologies ... Compendia
Bioscience
.....
Complete
Genomics ....
Complexa
..... Conatus
Pharmaceuticals ... Concert
Pharmaceuticals
.... Concordia Fibers ...Concurrent Technologies ...
Conductus
.. Confluence Life Sciences ..... ConforMIS ...
Cognigen
.... Conispire
.... ConjuGon .. Connecticut
Valley Bindery ... Consonus Technologies
...
Constellation
Pharmaceuticals .... Context Therapeutics ..... Contour Energy
Systems ControlRadSystems ..... Convelo
Therapeutics ....
Conventus
Orthopaedics ..... Convergen
... ConverGene .... Convio .... Convoy
Therapeutics
.... Cool-Bio
.... CoolCAD Electronics .... CoolChip Technologies
....
Cool Earth
Solar
.... Cooligy ... CoolTech .... Corbus
Pharmaceuticals
..... Corcept
Therapeutics
...
Cordex Systems .... CoreStreet ... CoreTek ...
.Corgenix
Medical
... Corindus ....Corinthian
Ophthalmic ... Corium International .... Corixa
....
CorMatrix
Cardiovascular
.... Cornami ..... Cornerstone Research
... Cornerstone BioPharma then Cornerstone
Therapeutics
..... Cornerstone Therapeutics .... Coronado
Biosciences ... CorQuest Medical ..... Correx ... Corridor
Pharmaceuticals
... Cortana ..... Cortendo AB ..... Cortexyme ....
Corvidia
Therapeutics ..... Corvus
Pharmaceuticals
..... CosmosID ..... CoStim Pharmaceuticals
.... Cougar
Biotechnology ...
Coulbourn
Instruments .... Coulter Pharmaceuticals ... Cour
Pharmaceutical
Development .... Coverity ..... Creare ...
Creative
Hybrid Solutions .... Creatv MicroTech .... Cree
Research ... Crescendo Bioscience .... Crinetics
Pharmaceuticals
....
CrispTek .... Critical Therapeutics .... CritiTech
... Crossbar .... Cross Current ..... CrossFire
... Cruise Automation .... Crux Biomedical
...
CryoCor ...
CryoLife ... Cryomedical Sciences ..... Cryptonite .....
Crystal
IS
...
Crystal Systems ... Crystallume ... CSA
Engineering ... CS-Keys ... CTD Holdings
..... CTI
BioPharma (formerly
Cell Therapeutics) .... Cubist
Pharmaceuticals
... Cue Biopharma .... Cumberland Pharma .... CuraGen ... Current Motor
...
Curtana Pharmaceuticals .... Custom Electronics .... CVD
Equipment ..... CVRx
... CV
Therapeutics ... Cyanotech ..... Cyberdyne .... CyberKey Solutions
... Cyberkinetics Neurotechnology ... Cybernet Systems
... CyberOptics ... Cydan .... Cykloburn
Technologies ..... CymaBay
Therapeutics
.... Cymbet ... CyMedica Orthopedics ..... Cymer
...
Cynosure ... Cyntellect ... Cypher Genomics ... CyPhy Works
... Cypress Bioscience ... Cyrus Biotechnology .....
Cyteir
Therapeutics ..... Cyterix
Pharmaceuticals ...
CytImmune .... CytoBioScience ..... Cytocentrics ..... CytoCore
(formerly Molecular
Diagnostics) ..... Cytocybernetics ..... CytoDyn
.... Cytogel Pharma
.... Cytokinetics
... Cytometix ....CytomX ...
Cytonome
....
Cytori Therapeutics ... Cytophil CytoSolv
... Cytosorbents ..... Cytovas ... CytRx ..... Cytyc
...
CyVek
Dabble ..... Dairyvative Technologies ..... Daktari Diagnostics ... Dance Biopharm .... Dara BioSciences ... Daré Bioscience Operations .... Dart Therapeutics ... DaStrong .... Datafiniti .... Data Physics ... DataRobot ..... Dato (formerly GraphLab) .... Datuit .... daydream.io ..... Daylight Solutions .... DayStar ... DBS Energy ... DCL Medical Laboratories ... Deca-Medics ... Decibel Therapeutics ..... DecImmune Therapeutics ... Deciphera Pharmaceuticals ..... Decision Biomarkers ... Deepwater Wind .. Defense Engineering .... Defense Research Associates .... Defibtech ... Dekkun .... Delcath ... Delinia ..... Deltanoid Pharmaceuticals ... Denali Medical ... Denali Therapeutics ..... Dendreon ... DeNovo Sciences .... DeNovis ... Deposition Sciences .... DermAvance Pharmaceuticals ... Dermira ... Desalitech .... Descartes Labs ..... Design Knowledge ..... DesignMedix ..... Detcon ..... DE Technologies ... Devicix ..... Dew & Ken Group ... Dewey Electronics ... Dexcom ... Dharmacon ..... Diagnostic Biochips .... Diagnostic Hybrids ... DiaMedica ..... Diamond Foundry ..... Diatomix ..... Dicerna Pharmaceuticals ... Diffusion Pharma ..... DiFusion Technologies ... Digene ..... Digirad ... DigiSight Technologies ..... Digital Fusion ... Digital Lumens ... Digital Optics ... Dignify Therapeutics .... Dimien .... Dimension Therapeutics .... DioGenix .... Dipexium Pharmaceuticals ..... Directed Manufacturing .... Directed Perception .. Disarm Therapeutics .... Disc Dynamics ... Discovery Genomics ..... Discovery Labs .... Displaytech ... Distributed Energy Systems ... Divergence ... Diversified Energy ... D. Light ... DMC Biotechnologies ... DNAnexus ..... DNAPrint Genomics ... DNAtrix .... DNV GL .... Dova Pharma ..... DoX Systems ... Dracen Pharma ..... Dragon Systems .. Dragoon ITCN ..... Drilling Info ... DrillMap .... DropWise .... DR Technologies ..... DrugCendR .... DSM .... DT Solar ... DuBay Ingredients ... duPont Aerospace ... Dura Biotech .... Durata Therapeutics ... Durin Technologies .... DVS Sciences .... DxUpClose .... Dyadic International ..... Dyax ...DynaBil Industries ... Dynasil ... Dynavax Technologies ... Dynetics .... Dynogen Pharmaceuticals
E3 Clean .... Eagle
Optoelectronics ... Earl Energy .... EarLens .... Earth Networks ....
Earthrise
Nutritionals ... eASIC ..... Eboo Pharmaceuticals .... EBR
Systems ..... Ebullient
....
Echelon .... Echodyne
..... Echometrix ... EchoPixel ..... Echo Therapeutics (was
Sontra)... ECI Biotech
... ECM Technologies ..... Ecocurrent
... EcoPesticides .... EcoPro Polymers .....
Eccrine Systems ..... Ecovative
Design ... Edaptive
Computing .... Eden
Bioscience
... Edenspace
Systems ... Edge Therapeutics ..... Edico Genome .... Edison
Agrosciences ..... Editas
Medicine .... EEStor
... Effector
Therapeutics .... Egalet .... eGenesis .... Eiger BioPharmaceuticals
..... Eikos ... E-Ink
... EIS .... Ekos ... EKR Therapeutics .... Ekso
...
Elcelyx Therapeutics ... Electrical
Geodesics .....
ElectroCell
Technologies
... ElectroChemical Systems ... Electro Energy
...Electromed ... Electro Optical Sciences ...
Electro
Scientific ... Elementary Robotics ....
Elemetric Instruments
... Elevation Pharmaceuticals ... Eleven
Biotherapeutics ... Elira Therapeutics
..... Elixir Biopharm ... Elixirgen Therapeutics ..... Elixir
Pharmaceuticals ...
Ellipse Technologies ..... Elon ...
Elstar Therapeutics ..... eMagin .. Embera
NeuroTherapeutics .... Embodied ....
EmboMedics
.....
Embrex ..
EMCORE
...
Emerald BioStructures
.... Emergent BioSolutions ...
Emergent
Technologies ... Empire Genomics .... Empire
Robotics ....
EMRes Technologies
... Emulate .... Enable
Injections ...... Enanta Pharmaceuticals ..... EnChroma ..... Encite
...
Encoded Genomics .... Encompass Bioscience ..... Encore
Vision .... Encysive
Pharmaceuticals ... Endeavor Robotics ..... Endece
...
Endgame Technologies
... EndoChoice .... Endocyte ... EndoGastric
Solutions
... Endo International ..... Endoscopic
Technologies ... Endosee ..... EndoStim
.... Endotherapeutics ..... Ener1
... EnerG2 ... Energen
... Energesis Pharmaceuticals .... Energetiq
Technology ... Energid Technologies ... Energous
..... Ener-G-Rotors
... Energy Control ... Energy Conversion
Devices .
.. Energy Focus ..... Energy Recovery ... Energy
Solutions
... Energy Storage Systems ..... EnerMat Technologies .....
EnerMed ..... Enertech
Environmental ... EnerVault ... Engineered
BioPharmaceuticals
.... Engineered Propulsion ...Engineous
Software
... Enlibrium ..... Enlight
Bioscience ... EnSync Energy Systems (formerly ZBB Energy)
.....
Ensysce Biosciences ... Entasis
Therapeutics ..... Entech
... Entegrion ... Entellus Medical .....
Entera
Biotech .... Entergem Ventures .... EnteroMedics
... Entia Biosciences ..... Entira Bio .... Entopica
Therapeutics
...
EntreMed
... Entrada Therapeutics ..... Entra Pharmaceuticals
... ENTrigue Surgical ...
Envia
Systems .. Entrotech Life Sciences ..... Entvantage
Diagnostics
..... EnviroFlight ..... Envisia Therapeutics
..... Envistacom .... EnVivo
Pharma ... Enzenia ... Enzium
... Enzo Biochem ... Enzymatics ... EnzyMed ..... Enzyvant
.....
EO2
Concepts
.... EOIR
... Eonix ....
EpiBiome ....
EpiBone .... Epicentre
Biotechnologies .... Epic Sciences .... Epic Systems ..... Epicypher
.... EpiEP ...
Epion
... Epiphany Solar Water Systems .... Epitomics
...
Epiva Biosciences ..... EpiVax ... EpiWorks .... Epix
Pharmaceuticals ... Epizyme
...
Eppin Pharma .... EqualLogic ... Equex
... Equillium .... Equipment
Concepts ...
EraGen Biosciences ... Erallo Technologies
... Erasca .... Ercole
Biotech ... ERT ..... Escalier Biosciences BV ..... Escalon
Medical
.... E-Scape
Bio ..... Escient Pharmaceuticals ..... Escoublac
....
eScription
... eSolar ... Eso-Technologies
... Esperance Pharmaceuticals ..... Esperion
Therapeutics
..... Essential Biotechnology
..... Essential Medical .... Essentient ....
Essex... Eta Devices ..... Eta-Gen .... Etegent
Technologies
... E-Tek
Dynamics ... Euclid
Labs .... Euclises Pharmaceuticals ..... Eureka
Therapeutics ..... Euthymics
Bioscience ... EVapt .... Evelo
Therapeutics ....
Evena Medical ..... Ever Cat Fuels
...
Evergen Biotechnologies ... Evergreen Solar ... Everspin
Technologies .... Evestra ....
Evident
Technologies ... Evoke Pharma .....
Evolution
Robotics ... Evolv .... Evolve BioSystems ....EWI .... Exact
Sciences .... Exagen
Diagnostics ... Excelimmune ... Excel
Technology .... Excision BioTherapeutics ..... Exelixis .....
Exelixis
Plant Sciences ... Exemplar Genetics .... Exo .....
Exogenesis
..... Exone ....
Exosome Diagnostics ..... Exovita
Biosciences .... ExploraMed
NC4 ...
Expression
Analysis .... Exquadrum .... Exsulin
....Extreme Molding ... Extremity Innovations ... EyeGate
Pharmaceuticals ... EyeNetra .... EyeTel
Fallbrook
Technologies
... Famigo ... Faraday Pharmaceuticals .... Farodox
Energy
Storage
...
FarSounder ... Far-Tech.... FastCAP Systems ...
Fate
Therapeutics
... Fathom .... Fe3 Medical .... FEI ... Femasys
.... Femta
Pharmaceuticals
.... Ferrate
Treatment Technologies ... Ferric Contrast ...... FerroKin
BioSciences ....
Fervo Energy .... Feuz Manufacturing ... FGC Plasma Solutions
..... Fiber and Sensor ....
Fiberight ...
Fiber Materials ... Fibersense ... Fiberstar ....
Bio-Ingredient
Technologies ... Fibertek .... Fibrocell Science
... FibroGen ... Filter
Sensing Technologies ...
Finally Light
Bulb ..... Finch Therapeutics Group ..... FineLine Prototyping ....
Finisar
... Fire Alarm
Specialty Design .....
Firefly
BioWorks ... Firefly Energy .... Firefly LED
...
First Solar ... Fisker Automotive ... Five Prime
Therapeutics .... Flex Biomedical
... Flexion Therapeutics ... Flex Pharma
.... Flextronics
America ....
Flexus Biosciences .... FLIR Systems
.. FloDesign
Wind Turbine ... FlowCardia
...
FlowMedica .... FlowMetric .... Flow Metrix
...
FluGen
... Fluidic Energy ... Fluidigm ... Fluid Innovation
Group
... Fluidnet ... Fluidnet
FluoroPharma
... Fog Pharma ..... Foghorn
Therapeutics .... FokusLabs .... FoldRx Pharmaceuticals
...
Follica ...
Footnote .... Foresight Biotherapeutics .... Forest Devices .... Forge
Therapeutics .....
F-Origin
... Forma
Therapeutics ...
Formlabs
.... For-Robin ..... ForSight Vision5 .... Fortis Therapeutics .....
Forty Seven ..... Forum Pharmaceuticals ..... Forus
Health ... Foster-Miller .... Foundation Medicine
... Fox Chase Chemical Diversity Center ....
Fractal
Antenna Systems ... Fractyl Labs ..... Freedom Meditech
... Free
Flow Power ... Free Form Fibers .... Freenome ..... Froedtert
Health ..... Frontier
NanoSystems ..... Frontier Technology ..... Front Range Biosciences
.... FTL Solar
...
FuelCell Energy
... Fuel Tech
.. Fulcrum Therapeutics ..... Fulgent Therapeutics ..... Full
Spectrum Genetics .... Furiex
.... Fused
Innocation.
...
Fusion
Coolant Systems ... Future Technologies
G1 Therapeutics ..... G3 .... Gadusol Laboratories (aka
Seaceuticals) ..... Galderma .... Galectin Thera ..... Galenea ...
Galena
Biopharma
.... Galera
Therapeutics ..... Galil Medical ..... Galleon
Pharmaceuticals ... GAM Enterprises .... GameSalad
... Gamma Medica Ideas ... Garland
Technology .....
Garwood Medical Devices ..... GATR Technologies ..... G-Con .... Gecko
Biomedical .... Gecko Robotics .... Gel Combs .... Gelesis ...
Geltech ...
Gema Diagnostics .... GEMFIRE .. Gemin X Pharmaceuticals
... Gemmus
Pharma ... Gemneo Bioscience ..... Gemphire Therapeutics
......
Gemstone
Biotherapeutics
..... Gen9 ...
Genaera ...
Genalyte
... Genapsys .... GenAudio .... Gene by Gene .... GeneCentric
Diagnostics
... Genelabs Technologies ... Gene
Logic ... Geneoscopy ..... General Compression
...
General
Pneumatics
..... Generation Bio ..... Generex
Biotechnology ... Gene Security Network .... GeneSegues
Therapeutics ..... GenesisLabs ....
GeneSystems ... Genetesis .... Genetic Networks ..... Genetix
Pharmaceuticals
... GeneTx Biotherapeutics ..... Geneu .... Genia
Technologies
.... GenMark Diagnostics
.... Genoa Pharmaceuticals ..... Genocea
Biosciences
... Genomatica
... Genome Profiling ... GenomeQuest ... Genomic Health
...
Genomind ....
Genoptix
Medical
Laboratory ... Genor ... Genprex .... Gen-Probe
...
GenSpera
.... GenTel BioSciences ... Gentris ... GenturaDx
...nbsp; GenVec ... GenWay Biotech ..... Genzyme .... Geocent
.... Geocove ..... Geomagic
... GeoMed
Analytical ... GeoVax Labs ...
Geospiza
... Germfalcon ..... Geron ...
Gevo
..... GI Dynamics
...
GigOptix
... Gilead Sciences .... Giner . ..
Ginkgo BioWorks
.... Glauconix ..... Glaukos
.... GlideLine
Systems ... Gliknik ... Global Blood
Therapeutics
...... Global Cancer Diagnostics ..... Global Positions ...
Global Blood Therapeutics ....
GlobeImmune ....
Gloucester Pharmaceuticals ... Glowforge ..... GlucaGo ...
GlycoFi
... GlycoMimetics .... GlyGenix ... Glympse Bio
.... Glyscend .....
GlySens
... GMZ
Energy
... GnuBio
.... Goddard Labs .... Goldfinch Bio ..... Good Start Genetics
.... Gore
Photonics ... Gossamer Bio ..... Gotham Biotech .... Gotham
Therapeutics ..... GPC-Rx
... gRadiant Research ... Gradiant ....
GraftWorx
..... Grail ..... Graphene
Energy
... Graphenix Development .... Graphic
Surgery ... GraphLab (now Dato) .... Grassroots Biotechnology
...
Greatbatch
... GrayBug ..... Graybug Vision ..... Great Basin Scientific .....
GreatGrow Maryland ....
GreatPoint Energy
... Green & Grow .... GreenFuel
Technologies .... Greenlight Biosciences .... GreenMark Biomedical
..... Green Mountain Radio
Research .... GreenSight Agronomics ..... Green Sulfcrete
.....
GreenTech America
... Greenwich Geriatrics .... GridBridge .... Grid
Therapeutics
..... Gritstone
Oncology
..... GRO Biosciences ..... Group14 Technologies ..... Grove
Instruments
... Grow Home Organics
.... GSI Technology ... GT Advanced
Technologies ...
GTC Biotherapeutics ... G-Tech Medical .... GT
Equipment .... GTI
Diagnostics
... GT Medical
Technologies ..... GTx .... Guardant Health .... Guided Surgery
Solutions
....
Guided
Therapeutics
.... .... Guided Therapy Systems ..... Gynesonics .....
G-Zero
Therapeutics
2 Energy Now ...... H2O Score ..... H2Pump ...
H2Sonics
.... H3
Biomedicine ... HNC Software ... Halozyme ...
Hana
Biosciences .... Hansen Energy and Environmental
....
Hansen Medical ... Haplogen Genomics ..... Harbor
Technologies .. Hardcore Computer ... HarkerBio .... Harmony
Enterprises ....
Harpoon Medical .... Harpoon Therapeutics .... Harvard Apparatus
Regenerative Technology .... Harrisvaccines .... Harvard Bioscience
... Harvest Automation .... Harvest Power ...
Harvest Technologies .... Healionics .. Health Diagnostics
Laboratories .... HealthMyne ....
Healthtronics
.... Hearforward
... Heartland Robotics .... HeartWare International
... Heat
Biologics .... ... HeatGenie ... Helicos
BioSciences
... Helion Energy .... Heliovolt ...
Helius Medical
Technologies ..... Helix
Therapeutics
... Helomics (formerly Precision Therapeutics)
.....
Hemadvance ..... HemaQuest Pharmaceuticals ... Hemarrest ... Hemera
Biosciences .... Hemispherx Biopharma .... HemoGenyx .... Hemoshear
Therapeutics ..... HemoSonics..... Hemostasis
... Hennepin Life Sciences .... Hepregen ... Heraeus Medical
Components .... Herley Industries
... Hermes Biosciences ... HexaTech
.... Hexfuel .... Hibernaid .... Highbury Defense
Group .... High Impact
Environmental
.... High Performance
Technologies ... High Point Pharmaceuticals .....
Histogen
.... HighRes Biosolutions .... Histogenics
... HistoRx
... HistoSonics .... HJM
Precision .....
HocusLocus ..... Hoku
Scientific
... Holaira .... Hollingsworth & Vose .... Hollis-Eden
Pharmaceuticals ... Holomni .... Homology Medicine
.....
Honeycomb Batteries .... Hontek
... Hoopers Island Oyster Aquaculture ...
Hoppe Tool
.... Hoth Therapeutics ..... Hsiri Therapeutics ..... HTG
Molecular ..... HTSS
...
Humacyte
...
Humanetics ..... Human
Genome
Sciences ...
Human
Metabolome Technologies .... HuTerra .... Huya Bioscience International
.... Hybritech ..... Hybrivet .... HYCOR
Biomedical ...
Hydra Biosciences ...
HydroCision ... Hydrogen
Safety ... HydroLogic Industries .... Hygeia
Therapeutics
... HyperBranch Medical
Technologies ... Hyperion Therapeutics ... HyperMed
... HYPRES .. Hy-SyEnce
... HyTrust
IAP ... IBC Advanced .... iBiquity Digital ..... Ibis
....
Iblogix
.... IBT
Laboratories
... Icagen .... Icardiac.... Ichor Medical Systems .... Iconic
Therapeutics ..... Icos.... ICX....
Idaho.... Ideal
Converters ... Ideapaint.... Ideaya Biosciences ..... Idera
Pharmaceuticals ..... ID Genomics ....
Idevices
... IDx ..... iFirst Medical Technologies ...... IFM
Therapeutics
..... Igenica
Biotherapeutics .... Ignyta.... Ii-IV
.... Ikaria... Ikonisys... Illinois Superconductor.... Illumigen....
Illumina.... Illuminating Diagnostics ..... Illuminoss....
Illumitex.... Imagen Energy .... Imagevision.... Imaging
Biometrics... Imagineoptix ... Imago Instruments... Imanis
Life...
Imbed Biosciences... Imetalx... Immco... Immersion... Immtech...
Immucell .... Immucor ....
Immune... ... Immune... Immune Pharma .... Immunetics...
Immunex...
Immunexcite...
Immuneworks... Immunexpress ..... Immunicon... ImmunoCellular Thera
.... ImmunoChemistry
Technologies ..... Immunocore...
Immunogen... Immunome ..... Immunomedics..... Immunomic Therapeutics
.....
Immunophotonics ... Immurx... .... Immusant...
Immusoft ..... Impact Biomedicines .... Impact Proteomics
.... Impact Science...
Impel
Neuropharma... Imperium Renewables... Impinj... Implant
Sciences... Impossible Foods .... Imprimis Pharmaceuticals .... Imprint
Energy .... Impulse
Monitoring ... Imricor Medical Systems ..... Imris .....
Imthera...
I-nalysis ... Inari Agriculture .... InCarda Therapeutics ....
INCELL .... Incelldx
..... Incitor (now XF
Technologies) .... Incodema3D ..... Incontrol
Research... InCube Labs ..... Incyte ....Incytu... Indalo
Therapeutics ..... Indiana
Nanotech... Indi Molecular ... Industrial Heat ..... Industrial
Perception...
Inentec ... InfaCare Pharmaceutical .... Infarct Reduction
Technologies .... Infinera...
... Infinia... Infinity... Infinium
.... Inform
Genomics... Infoscitex... Inframat... Infraredx... Infrascan... Inf
Robotics ... Infusion Medical ... Ingeneus... Ingeneron .....
Inhibitex... Inhibkase
Therapeutics .... INI
Power... Inland Labs ..... Inmobly .... InnAVasc Medical ....
Inneroptic...
Innerpulse... Innocrin Pharmaceuticals ..... Innography...
... Innopad... Innotec ..... Innovalight...
Innovari Energy Design Microplate Scientific...
pulmonary solutions.... silicon... Innovate Biopharmaceuticals .....
Innovative Spinal...
Innovative... Innoventiontech ... Innovention (now
Ccardiorobotics) ... Innovative Trauma or...
Innovolt ...
Innowave... ... ... Innoviva ...
Innov-x... Inocucor ..... Inorganic Specialists... Inotek...
Ino
.... Inova
Labs
Biomedical... Inovio... Inovise Medical ..... Inozyme Pharmaceuticals
..... Inphase...
... Inphi... Inpria ..... Inscripta ..... Insert MRI...
Insight...
..Insite Vision...... Insitu... InSitu
Biologics ..... Insmed... Inspired Solar Systems ...
Inspire...
Insulet
Labs
... Intact Vascular... Intaglio... Intalio ... Intarcia
Therapeutics ...
Integenx... Integra Group Diagnostics... Integral Molecular .....
Integrated BioTherapeutics
.... Integrated
Diagnostics .... Integrated
Diagnostics InDi .... Integrated DNA Technologies ..... Integrated
Fuel...
... Integration Associates... Intelect
Medical
Intelleflex ... Intellia Therapeutics .....
Intellicyt
Automation Bio-systems ...
Intelligent Devices .... Intelligent Epitaxy Technology .....
Intellimedix ..... Intelliphage.... Intellirad
Control...
.Intellisense .... Intelomed ....Inter-4... Interactive Supercomputing
... Interdigital
Interlace ....
Intermagnetics General ...Intermolecular ... Intermune....
International Stem Cell ... Interrad Medical ..... IntersectENT ....
Intersense...
Intersystems ...
Intervalve....
Intevac.... Intra-Cellular Therapies .....
Intralase ...... Intralytix .... Intrexon ..... Intrinsity....
Introgen....
... Intuitive Biosciences .... Intuitive Genomics ..... Intuitive
Surgical.... Invenra ....
Invensense .... Inventev ..... Inverness
Innovations.... Invirsa ..... Invertix.... Invictus.... Inview
Technology....
Inviragen.... Invisage Technologies ....
....InvisionHeart .... Invision Medical ....
Invitae....
Invitrogen.... ...Invivosciences.... Invivo Therapeutics=
Holdings .... Invuity....
Inx Medical.... IoGyn .... Iomai.... ... Iomed....
IOmet
Pharma ..... Ion America Optics..... Ionic Materials ..... Ion
Torrent.... Iovance Biotherapeutics ..... Iovation.... Iowa Thin
Film....
Ipierian.... IPG Photonics.... ... Iquum
...Irhythm...
iRobot... Iroko...Ironbridge.... ... Ironwood....
... .... Irvine Sensors... .... biopolymer
. .... Ischemia Care.... iSee ..... iSIGHT
Partners
.....
Isis.... Island Ddata....
Isogenis.... Isomark.... IsoPlexis .... Isoray....
Isothermal....
Isthmus Biosciences ..... IstoTechnologies....
itaconix....
I-Therapeutix..... Itherxm Pharmaceuticals.... Itraumacare... .. Itseez
..... Itzbig ..... Iwalk
Jade Therapeutics ..... J&Y ... Janssen Biotech .... Janus Biotherapuetics ... Javelin Pharmaceuticals ... Javelin Semiconductor ... JDP Therapeutics ..... Jennerex ... Jnana Therapeutics ..... Joule Biotechnologies .... Jounce Therapeutics .... Joyent .... Joylux .... Juno Therapeutics ..... Just Biotherapeutics
K2M .... K2 Therapeutics .... KAER
Biotherapeutics .... Kala
Pharmaceuticals ... Kallyope ..... KaloBios
Pharmaceuticals
..... >Kalocyte .... Kalon
Biotherapeutics ..... KalVista Pharmaceuticals .... Karius .....
Karyopharm Therapeutics ... Kateeva
..... Kayo
Technology ..... KaZaK
... KC BioMediX ... KCI .... KDH Defense Systems
... Kebotix .... Keithley Instrument ...
Kelyniam ...
Kenall
Manufacturing
..... Kensey-Nash
... Kent Displays ... Kentucky
BioProcessing ....
KeraNetics .... Kezar Life Sciences ..... KeyW .... Kilawatt
Technologies ... Kindara .... KinDex ... KindHeart ..... KineMed ....
Kinestral Technologies ..... Kineta ...
Kinetic
Concepts .... Kinex
Pharmaceuticals .... Kingbright .... Kior .....
Kips Bay
Medical ... Kite Pharma ..... Kitware ...
Kiva Systems ... KLD
Energy Technologies .... Klotho Therapeutics .... KMel
Robotics .... Knightscope
.....
Knome ...
Knopp
Neurosciences .... KNOW Bio ..... KnuEdge .... Koam
Engineering Systems .... Kodiak Sciences
.... Kolltan
Pharmaceuticals
...
Komoku ... Kona Medical .... Konarka ... Koning ...
Kopin
.. KOR
Electronics ...
Koronis Pharmaceuticals ... Kosan Biosciences ... Kosmetikos
....
Kovio ... KPI
Therapeutics (from Kineta)... Kraig Biocraft ..... Kratos Defense
& Security
Solutions
.... Kronos Advanced
Technologies ... Krystal Biotech .... KSE
... KSQ Therapeutics ..... Kultevat ..... Kura Oncology ....
Kumu Networks .... KVH
.. Kylin
Therapeutics
...
Kyma ....Kymera Therapeutics ..... Kymeta
... Kyn Therapeutics .... Kyocera
Solar .... Kypha ..... Kyras Therapeutics ..... Kyron Clinical Imaging
.... Kytopen
LAAMScience ... LaBelle
Associates .....
LabNow
...Laborie Medical Technologies ... Labrys Biologics ... Lacerta
Therapeutics ..... Lactic
Solutions ..... Laguna
Pharmaceuticals (formerly ChanRx) ..... La Jolla
Pharmaceutical
... Lake Shore Cryotronics .... Landec
.... Landos Biopharma .... Lantern
Pharma ..... Lantheus
...
Lantos
Technologies ... Lariat Biosciences .... Laser
Design .... Lasergen ..... LaserMax ..... LaserMotive
... Laser Tissue
Welding .... Lattice Biologics ..... Lattice
Biotech ....
Lawrie ... Lazarus Effect ..... LDR
Holding
..... Lead
Therapeutics
... LeafBio .... LeCroy ... LED Lighting
Fixtures
... Lehigh
Technologies .... Leica Microsystems
.....
LetoSolutions .... Lexicon
Genetics
... Lexicon Pharmaceuticals ... Leyden Energy ... Libra
BioSciences .... LifeCell ... LifeGen
Technologies ...
Life Image ... LifeMine Therapeutics .... LifeSprout ....
Life Technologies
....
Ligand
Pharmaceuticals ....Ligon Discovery ... Lightpointe
... Light Sciences Oncology ... LightWorks Optics
....
Lilliputian Systems
.... Lily Robotics ..... Linares Management
Associates
.. Lingotek
... LinQuest .... Lionano .... Lion Biotechnologies ..... Lipocine ....
LipoScience
...
Liquid Biotech ..... Liquidia
Technologies ...
Liquid Light ...
Liquid Metal
Battery ...
LiquidPiston ... Liquid Robotics ... Liquid X Printed Metals
....
LiQuifix ...
Lithium Technology
... LiveData ... . LiveLeaf
Bioscience .... Locus Biosciences .... Lodo Therapeutics .... Logical
Therapeutics
... LogicBio Therapeutics ..... Logos
Tech
... Lohocla Research
.....
Lombard Medical ..... Longeveron ..... LonoCloud .....
Lookingglass ..... Loon Medical
..... Lotus Tissue
Repair
...
Loxo Oncology ... LPath Thera .... Lq3 Pharmaceuticals ....
LS9
...
Luca
Technologies .... Lucerno Dynamics .... Lucidux ...
Lucigen
.... LumaSense Technologies .... Lumena
Pharmaceuticals .... Lumen Bioscience .... Lumencor
... Lumense .... Lumera ... Lumicell Diagnostics
...
Luminary
Micro ...
Luminex .... Luminus Devices ... Lumisyn
..... Lumitex
... LumiThera .... Lumos Pharma .... Luna Innovations
... Luna
Technologies
... Lung Therapeutics .... Lutonix
...
Luxtera
... Lycera ... LyGenesis ..... Lyncean .....
Lynntech ... Lynx Biosciences ... Lyra Therapeutics ..... Lysosomal
Therapeutics ....
Lytro Therapeutics
M3 Biotechnology .... MabVax .... MacAulay-Brown
..... Macrochem ...
MacroFab ..... Macrogenics
... Macrolide Pharma ..... Macrophage Therapeutics ....
Madison
Vaccines .... Madrigal Pharmaceuticals ..... MagBioSense ..... Magenta
Therapeutics ..... Magic Leap
..... MagneMotion ...
Magnesium Development ..... Magnetek ... Magnolia
Medical
Technologies .... Magnolia Optical
Technologies
... Magnolia Solar ... Mainstay Medical International ......
Mainstream Engineering ... Major
Pharmaceuticals .... Mako Surgical
... Manhattan Scientifics ..... Mantra Bio .....
>Manufcturing Techniques ..... MapInfo
...MAP
Pharmaceuticals
... Mapp
Biopharmaceuticals .... Marathon Pharmaceuticals ..... Marcadia
Biotech
... Marina Biotech ... Marinus
Pharmaceuticals
... Maritime Applied Physics .... Marrone Bio Innovations
....
Martek Biosciences ...
Mascoma ... Mashery
... Mason Box ... Masten Space Systems
... Masterson Industries .... Mast Therapeutics
(formerly
ADVENTRX) .... Material Sciences ... Material
Technologies ... MathStar ... Mati
Therapeutics .... Matouk
Textiles ... Matritech ... Matrix Product Development
.....Matrix
Research ....
Matrix Sensors ... Maverick Therapeutics .... MAX
BioPharma
...
MaxCyte ...... Maxdem
... Maxpower ... Maxygen ....
MBio Diagnostics
.... MC10 .... MCube .... M
Cubed Technologies .... MD Biosciences ..... MDSolarSciences
... Mebias Discovery ..... Mechanical
Technology
...
Mechanology ... Medafor ...
Medarex ...
MediBeacon .... Medicago USA .... Medical21 ..... Medical Cyberworlds
.... Medical
Device Logistics ...
MedicaMetrix... Medgenics ..... MediciNova .....
Medicool
Technologies .... MedImmune ..
Medina Medical .... Mediomics .... Medior Therapeutics .... Medis
... MEDITE Group .... Medivation ... Mednology Solutions ....
Medrobotics ...
MedShape .... MedSocket (formerly 1CDS) ...... Medsphere Systems .....
MedTel ..... MEI Pharma
..... Meka .... MELA
Sciences .... Melinta Therapeutics .... Melior Discovery .... Memjet
...Memry ...
Memsic ... MEMS Optical...Menlo Therapeutics ..... MER
...
Mercator Therapeutics ... Mercury Computer
Systems .... Merganser Biotech ....
Merge
Technologies ... MeriaGTx ..... Meridian Bioscience
... Meritage Pharma ..... Merkatum ... Merrimack
Pharmaceuticals
... Meryx .... Mersana Therapeutics ... Mesa
Photonics ... Mesocopic
Devices ... Metabasis ... Metabiota .... Metabolic Solutions
Development .... Metabolex .... Metabolix
... MetaCarta ... Metacrine .... Metactive Medical
.....
Metal Oxygen
Separation Technologies ... Metamark Genetics ...
MetaModix
... Metavention ..... Metompkin Seafood .... MetroLaser ...
MGC
Diagnostics
...
MIACH Orthopaedics ..... Misaole .... Micell
Technologies
... Michelman ... Micracor .... Micrel ... MicroCoating ...
Micracor ....
Microbe Detectives
... Microbia ... Microbot Medical ... Microfluidics International
(Microbia)
... MicroGreen
Polymers .... MicroIslet ...
Microlin Bio ....
MicroMask ...
Micronics ... MicroOptical (New
Mexico)... MicroOptical
(Massachusetts) ... MicroOptx ..... MicroPower Technologies
...
MICROrganic Technologies .... MicrowSat
Systems .... Microscopy Innovations ..... Microstaq
... MicroTransponder ..... Microvision ... MicuRx
Pharmaceuticals
.... Midori Renewables
..... Mid Valley
Industries
... Millendo Therapeutics (born as
Attercor) ..... Million Concepts ..... Miltec .... MiMedx Group ....
MimiVax ....
Minerva
Biotechnologies
... Minerva Neurosciences .... Minerva Surgical
.... Minimally Invasive Devices .... Minnesota
Thermal Science ..... Minnetronix ... MIOX ..... Mirador Biomedical
... Mira Dx ... MiRagen
Therapeutics .....
Miramar Labs .... Mirati Therapeutics ..... miRecule .... Mirimus ...
Mirina ... Mirna
Therapeutics.... Miromatrix Medical ...
Mirus Bio ....Mirum Pharmaceuticals ..... Mission Bio ..... Mission
Research ...
Mississippi Polymer ... Mithridion ...
Mitochon Pharmaceuticals ..... Mnemosyne
Pharmaceuticals ...
Mobile Robots ... Mobius Therapeutics ..... Moderna Therapeutics ....
Modern Meadow .... Modern Technology Solutions
.... Moduline Systems .... Modumetal ..... MOgene Green Chemicals ....
Molecular
Biometrics
... Mohawk
Innovative Technology ..... Molecular
Detection ... Molecular Diagnostics .... Molecular Imprints
... Molecular
Insight
Pharmaceuticals ... MolecularMD ... Molecular
Sensing ...
Molecular
Templates
.... Moleculin Biotech ..... Molten
Metal .. MoMelan Technologies ... Momenta
Pharmaceuticals ... Monebo ... Monogram Biosciences
.... Monteris Medical ..... Morphic Therapeutics
.....
Morphormics
... Morphotek
...
Morris
Innovative Research ... Mortara Instrument ...
MortaSecurity .... Motricity
... Motus Therapeutics .... Mound Laser
& Photonics Center ..... Movia Robotics ..... Moximed .... MPP
Group ... MPSP ...
MSNW ....
Mudawar Thermal
Systems
.....
Munksjo Paper ... Muons ... Muse bio .... Myco
Technology
....
Myocor
... MyoKardia
...
Myomo
... Myonexus Therapeutic ..... Myovant Sciences
.....
Myriad Genetics
...
Myriant
Technologies
... Mystic Pharmaceuticals
N12 Technologies
... (N30 Pharmaceuticals) now Nivalis Thera .... NABsys
... Nalas
Engineering ....
NanOasis Technologies ... NanoBio
...
Nanobiosym ... Nano-C ... NanoCellect (formerly NanoSort)
.....
Nanocomp Technologies ...
NanoCoolers ... Nanocopoeia ... NanoCor Therapeutics
...Nanodynamics (Buffalo) ... Nano DX ..... Nanodynamics
(NYC)...
NanoeXa
.... Nanofiber Solutions ... Nanogen ... NanoGraf (formery SiNode)
..... NanoGram .... nanoGriptech
..... NanoH2O ... Nanohmics ... NanoLab
... NanoLite Systems ... NanoLogix ...
NanoLumens
..... Nanomaterials
Research
... NanoMatrix ... NanoMedex ... NanoMedicalSystems
...
NanoMedical Systems .. Nanomix ... nanoMR ..... Nanophase
Technologies
... NanoPhotonica ... Nanopore Diagnostics ..... Nanoptek
... Nanoramic
Laboratories (formerly FastCap Systems) ..... nanoRETE .... Nanoscale
Components ...
Nanoscale
Materials
... Nanosolar ...
Nanosonic ... Nanospectra Biosciences .... Nanosphere ... NanoSteel
...
Nanostim .... NanoString
Technologies .... Nanosys ...
NanoSystems ... Nano Tailor ... Nanotek Instruments
.....
Nano-Terra ... Nanotherapeutics ..... NanoTune Technologies
... Nanova
....
Nanovation
Technologies ... NanoVault Medical .... NanoViricides
... NanoVision Diagnostics .... NantCell
..... Nantero
... Napo
Pharmaceuticals ... NantKwest ..... Narus
Biotechnologies ..... Nascentric
... Nastech
Pharmaceutical ... Natera .... National Technical Systems
..... Natural Molecular Testing ..... NaturalNano ...
Nature's
First .....
Natus Medical ... Naverus ... Navidea
Biopharmaceuticals ... Navini Networks
... Navire Pharmaceuticals .... Navitor Pharmaceuticals ....
Navmar Applied Sciences
... NBD Nanotechnologies ....NCD Technologies
.... nContact
Surgical ...
Neah Power ... Near Infinity .... Neato Robotics ... Nektar
Therapeutics ... Nekton
Research
.... NemaMetrix .... NeoChord ... Neogen
.... NeoGenomics ..... Neograft
..... NeoLight ..... Neon Therapeutics ....
NeoPhotonics ... Neoprobe
...
Neos Therapeutics ..... NeoSync ..... Neothetics .... Neotron
...
NephroGenex .... Nereus
Pharmaceuticals ... Nest .... Netcentric .... Netezza ...
NetLogics
Microsystems... Netspeed Systems ...... Net Watch
Solutions
..... NetworkFab
...
NeurAccel
Biosciences ...
Neurala .... Neural Analytics .... Neuralstem .... Neuraly
..... Neuraptive
Therapeutics .....
Neuro
Amp .... Neurobiological
Technologies
...
NeuroChaos Solutions .... Neurocrine Biosciences
...
NeuroDx Development ... NeuroEM .... Neurodyne Medical ...
Neurofluidics ....Neurogastrx .... Neurogen
... NeurogesX ...
Neurognostics .. NeuroHabilitation .... NeuroLogica
.... NeuroLutions ..... NeuroMap
... Neuro Kinetics ....
NeuroMetrix... Neurona Therapeutics .... Neuronetics .
Neuronex .. NeuroOne ..... NeuroPace
...
NeuroPhage
Pharmaceuticals
... Neuron Systems ... NeuroPointDX
..... Neuroptix
... Neuroscience .... NeuroTek .... Neurotrack ....
NeuroTronik .... Neurotrope ..... Neurovance
... NeuroVigil ...
Neurovascular
Diagnostics ..... NeuroVision Imaging .... NeuroVista ....
NeuroVive
.... NeuWave
Medical ...Nevro ... New Dominion Enterprises ..... NewLeaf
Symbiotics .... NewLink Genetics
.... Newlink genetics england ... biolabs ...
new
era technology ... New Haven Pharmaceuticals ... Nexant
...Nexbio
... NexImmune .... NexPlanar .... NextCODE Health ....
NextCure ..... Nextio ....
NEXTracker
....Nextreme Thermal Solutions ... NextStep Robotics .....
Nexus
Biosystems ..... NG1 Technologies .... NGM Biopharmaceuticals .... Nico
..... Night Vision ...
Nimblegen Systems ... Nimble Storage ....
Nimbus Discovery ... Nimbus Therapeutic
.....
Ninepoint
...Niowave ... NIRvana Sciences .... Nitero....
Nitric Biotherapeutics
....Nitricgen ... Nitride Solutions .... Nitrogenics .....
Nitromed ...Nitronex
... Nivalis Therapeutics formerly N30 Thera ..... NKT
Therapeutics ...
Nlight ... NMT Medical .... Noah
Technologies ....
Noble Fiber
... Nohla Therapeutics .... Noivatone .... Nok Nok
Labs
....
Nomadics .... NONA Composites .... Noninvasix ....
Nonvolatile
Electronics .... Nora Therapeutics .... Norian ... NorMedix
.....
Normoxys
.... Norse .... Northeast Photosciences
... Northstar Medical
Radioisotopes .... Northstar Photonics...
Northwest Biotherapeutics .. Norwich Technologies ....
Nostopharma .... Notice
Ttechnologies ... .Novacea
... Novalar Pharmaceuticals ... Novalux
... Novan
Therapeutics .... NovaScan
... Nova Synthetix .... Novatek ... NovaTorque
... NovaTract
Surgical
... Novavax .... Novazyme Pharmaceuticals ..... Novecon
Technologies ... Novella
Clinical
.... Novelos
Pharmaceuticals
... Novelos Therapeutics ... Noveome Biotherapeutic
.....
Novian Health .... Novira
Therapeutics ...
Novocell ... Novogy
... Novomer ...
Novophage ... Novo Sol-u-tions MD .... Novosource ...
Novozymes .... Novus Biologicals ....
Noxilizer
... Nox Technologies ... NP Photonics ...
NPS Pharma ..... NRGindependence ..... NSS Labs
..... Nucelis
.... Nuclea
Bioechnologies ... Nufern .... NuGEN Technologies ..... NuMat
Technologies ..... NuMedii
.... NumereX .... NUMiX Materials ..... NuPathe .... Nurel
(now PeriphaGen) ....
Nuron
Biotech ... Nutrabiotix
... Nutrient Recovery and Upcycling .... NuVant
... NuVascular Technologies .... Nuve ..... Nuventix ...
Nuvera Biosciences ... Nuvera Fuel Cells.. . Nuvotronics
.....
Nuvox
Pharma ..... Nu Waves ..... NxThera ... Nvision
Biomedical
Technologies ..... NZ
Applied Technologies
Oak-Mitsui .... Oasys ...
ObjectVideo
... Obsidian Therapeutics ..... OBS
Medical ... Ocarina Networks ... Ocata Thera ...
Occipital
....
Ocean Power
Technologies
... Ocean Renewable Power .... Ocera Thera .... OCI ...
Ocugen ..... Ocular
Therapeutix
....
Oculeve
... Oculus ... Oddpost
... Odyssey Systems
Consulting Group ... Oil Chem
Technologies ... OLEDWorks .... Omeros
... OmniGene Bioproducts ... OmniGuide ...
OmniLytics
... Omniox ..... OmniSonics Medical Technologies
... Omnis
PharmaRebiotix .... Omni
Water Solutions ... Onboard Dynamics .... ONCE Innovations
.....
OnChip
Power .... Oncobiologics ..... Oncogenex
... Oncolmmune ..... Oncolinx .... Oncolix ..... Oncolytics
Biotech
...
OncoMed
Pharmaceuticals .... OncoNano Medicine .... Onconova
Therapeutics
...Oncoscope
...
OnCore Biopharma ..... OncoResponse ..... Oncorus .....
OncoSec
Medical
.... OncoTartis ...... Oncothyreon
... Oncovista Innovative Therapies ..... Onduo ..... One
Resonance Sensors .... Onko
Solutions .... ONL
Therapeutics ....
On-Q-ity .... Onspira Therapeutics .... On Target
Laboratories
.... Ontela ..... On-X
Life
Technologies ....
Onyx
Pharmaceuticals ... Oorja
Protonics .... Open Algae ... Open Monoclonal Technology
.....
Open Silicon
... OpenWater
Power .... Opertech Bio ..... Opexa
Therapeutics
... OpGen ... OPNET Technologies
... Opsonix .... OptTek
Systems ... Optelecom ...Optelecom-NKF ... Optherion ...
Optical
Concepts .. Optigain .. Optimal Technologies ... Optimus
Technologies .... OptiNose .... Optivision
...
Optofluidics ... OptoLum ..... Optonicus .... Opto Technology
...
Optomec
....
OPX
Biotech
... Oragenics .... OraMerix
... Orasi Medical ... OraSure
Technologies ....
Orbital
Technologies
... Orbotix .... Orchard Therapeutics ..... Orchid
Cellmark
... Oregon Iron
Works .... Orexigen
Therapeutics
... Organic Research .... Organogenesis ...
Organovo
..
ORIC Pharmaceuticals ..... Oricula Therapeutics .... Origin
Medsystems ..... OriginOil
... Orion Energy Systems ... Orion Genomics ...
Ormet
Circuits ... Orologic... OrphoMed ..... Ortel ...
OrthoAccel
Technologies ... Ortho Kinematics
.... Oryx Technology ...Oscient Pharamceuticals ...Oscilla
Power
.... Osiris
Therapeutics ... OSI Pharmaceuticals ... Oso Biopharmaceuticals
Manufacturing .... Osprey Medical ....
Ossianix
... Ostendo Technologies ...
Osteotech ... Osterhout Design Group .... OtoNexus Medical
Technologies .... Otonomy .... OtoSense
.... Ottomatika .... Outset Medical .... OvaScience ...
>Ovid Therapeutics ..... Oxalo Therapeutics .... Oxford
Performance Materials ... Oxis International .... Oxygen
Biotherapeutics
P3I ... Pace Packaging .... Pacific Biosciences
.... Padlock Therapeutics .... Pain Therapeutics ...
PaizaBio .... Palantir Technologies .... Palleon Pharmaceuticals ....
Palmaz Scientific ..... Palmer
Labs
...
Paloma Pharmaceuticals ... Panacea Solutions ....
Panacos
... Pandion ..... Pandromics ..... Pan Genome Systems .... Panomics
..... PanTheryx .... Paper
Battery ....
PapGene .... Parabricks .... Paradigm Diagnostics
.... Paradigm
Sensors
... Paradromics ..... ParaGen Technologies ..... Paragon
Bioservices ..... Paragon Dynamics
...
Paragonix Technologies .... Parasol Therapeutics
... Paratek
Pharmaceuticals .... Parexel International .... Parion Sciences
... ParkerVision .... Partner Therapeutics ..... Partpic ....
Passport
Systems ... Pasteuria Bioscience ... Pathfinder ...
PathoGenetix
... PathoVax ..... Pathway Genomics .... PatientStream ...
PatientWise ...
Patton Medical Devices ... Patton Surgical .... Pavilion
Technologies ... Pax Streamline ... PaxVax ...
PDI Therapeutics ..... PDL
BioPharma ... PDS Biotechnology ..... Pearl
Therapeutics
... Pear Therapeutics ..... PECA Labs
.... Pediatric Bioscience .... Peerless Technologies .... Pegasus
Sustainability Solutions ....
Pelican
Products ..... PellePharm .... Pellion
Tech ... Peloton Therapeutics ..... Peninsula
Pharmaceuticals ..... PennAlt Organics ..... Penumbra .....
PeproMene Bio .... Peptimed
... Peptilogics .... Peptimmune
... Perceptive Navigation ..... Perceptive Sciences
... Perceptron ....
PercipEnz
Technologies
... Peregrine Semiconductor .... PeriphaGen .... Permeon
Biologics
...
Perosphere .... Perscitus Biosciences ... Perseon .....
Persimmon
Technologies ....
PersonalBee ... Personalis ...... Personal Genome
Diagnostics
.... Pervasis Therapeutics
... Pervasive
.... Petra Pharma ..... Pfenex ...
Pharmacyclics
.... PharmaJet .... PharmAkea Therapeutics ....
Pharmasset
... PharmAthene
... PharmatrophiX .... PhaseBio
Pharmaceuticals .... Phase Bioscience ... PhaseRx ....
Phigenix
..... Phoenix Biotechnology .... Phoenix
Nuclear Labs ...
Phoenix Science .. Phononic
Devices
... Photobit ... Photolitec .....
PhotoMedex
... Photonics
Innovations ... Photon-X ....
PhotoSonix Medical .... PhotoThera
...
Photronics ... Phoundry Pharmaceuticals .... Phrixus
Pharmaceuticals ..... Phurnace
Software ...
Phylonix
.... Phylos Bioscience ..... Physcient .... Physical
Optics... Physical
Sciences
... PhysioGenix
... PhysioSonics ... PhytoTech ... Picolight ....
Picometrix
... Piedmont Biofuels .... Pieris Pharmaceuticals ..... Pika
Energy ... Pilus
Energy ....
Pinger
...
Pinnacle Technology ... Pioneer Surgical
Technology .... Pionyr Immunotherapeutics ..... Pivot
Bio ..... Pixelligent .... Pixel
Optics .. Pixim ... Pixtronix ... Plakous Therapeutics .....
Planar Energy
...
Planar Systems ... Planet Labs .... Plano Microwave ..... Plasan ...
PlasmaTech Biopharmaceuticals .... Platelet
BioGenesis .... Platypus
... Play-i
.... PLC
Medical Systems
... Plextronics ... Plexxikon
... Pliant Therapeutics .... Plug
Power ... Pluromed ... PLx Pharma ..... PLX Technology ....
PMT
.... PMV Pharmaceuticals .... PneumRx .....
Point Source .... Polarean ..... Polatis
.... Polychromix
...
Polyera ... PolyMedica ... PolyMedix ... Polymer
Technology
Systems ... Polynoma ..... PolyNova .... PolyPlus ... PolyRemedy ...
Polysciences ... Polystor ... Portola
Pharmaceuticals ...
Possis Medical ... Pothole Pros ... PowerGenix ...
Powerlight
... Power
Precise Solutions ... PowerVision ... Pozen ...
Prairie
Technologies ..... Pranalytica ... Praxis Biotechnology .....
Precision Biopsy
...
Precision BioSciences
.... Precision for Medicine .... Precision Genome
Engineering .... Precision Ocular Metrology ..... Precision Optics
...
Precision
Therapeutics (now Helomics) .... Precision Virologics .... Predictive
Biosciences
... Pregmama ..... Presage Biosciences
... Presidio
Pharmaceuticals
.... Pressure BioSciences
... PreTalen ..... Prevail Therapeutics ..... Preventice .....
Prevention
Pharmaceuticals ....
Prieto Battery ..... Primary Data ..... Primera
Biosciences ... Primordial .... Primorigen Biosciences
... Primus Power .... Princeton Satellite
Systems ..... Principia Biopharma ....
Prism
Solar Technologies .... Procept BioRobotics ..... ProCertus
BioPharm
... Processa Pharmaceuticals .....
Proclara
Biosciences (formerly
NeuroPhage
Pharmaceuticals) .... Procyrion .... Profectus BioSciences .
.. Progenics
Pharmaceuticals
... Progenity .... Progeny Systems ..... Prologic
...
Promedior
...
Promega .....
Promentis
.... Pronutria ..... Propagenix ..... Propeller
Health ....
Propulsive Wing
.... ProstaGene ....
Protagonist
Therapeutics .... Protein Foundry ..... Protein Sciences
... ProteinSimple (formerly Cell
Biosciences) .... Proteon Therapeutics
...
Proteostasis
Therapeutics
... Proteotech ... Proteus
Biomedical
... Proteus Digital Health .... Protez Pharmaceuticals
.... Prothena .... ProThera Biologics ...
Proto Labs ... Proton Energy Systems ...Protonex ..
Prototype
Productions .Provagen ... Provenance Biopharmaceuticals
... Provention Bio .... Proventys
... Provista Diagnostics .... Pryor Medical Devices .....
PsiKick
..... pSivida
... PTC Therapeutics
.... Pulmatrix ... Pulmonx .... Pulmotect ..... Pulse
Electronics ....
PulseTherapeutics .... Puma Biotechnology ..... PUR
Biologics ..... Pure Bioscience .... Purfresh
... Purillume ..... Pursuit Vascular ... PurThread
.... PvP
Biologics
Qcept Technologies .... Qcue .... QD Vision
...
QED ... qFuzion ..... Qioptiq
... QM Power
... Qpex .... QPixel ... QR
Pharma
... QSpex .... Qteros
... QuaDPharma .... Quadra-Aerrow International ...
Quadraspec
...
Quad Technologies .... Qualcomm ... QualityMetric
...
Qualtech Systems ....
Qualtré ... Quanterix
... QuantRx Biomedical
.... Quanttus .... QuantTera .... Quantum Circuits ..... Quantum
Epitaxial
Designs ... Quantum Fuel Systems... Quantum Logic
Devices
... Quantum Materials .... QuantumSphere
.... Quantum Xchange .... Quark
Biotech ... Quark
Pharmaceuticals ... Qubitekk ..... Quentis Therapeutics .....
Quick–Med
Technologies .... Quid ..... Quidel
... Quincy
Bioscience
... Quintessence Biosciences ... Quorum
Systems
Radant Technologies ... Radiabeam Technologies
... Radiance Technologies .... Radiant Photonics...Radiation
Monitoring Devices
... RadioMedix ... Radius
Health ....
Rafagen ... Rainbow Organic Farms ... RainDance
Technologies
...
RainStorm ...
Rain Water Solutions ... Rallybio ..... Raland Therapeutics .... RaNA
Therapeutic ...
RAN Biotechnologies .... Range Fuels
... Rapamycin Holdings ..... RaPharmaceuticals
... Rapid Diagnostek ... Rapid
Micro Biosystems
... Rapiscan ... RareCyte ..... Raser Technologies
.... Raydiance ... Raydiant Oximetry .... Raymond
.... Raze
Therapeutics
.... RE2
.... Ready Robotics ..... Reata Pharmaceuticals .... Rebellion
Photonics .... Rebion ..... Rebiotix ....
Receptor Logic ...
Receptos
..... Recodagen ...
Recombinetics
... ReconRobotics
.. Recovery Engineering ..... Recro Pharma ....
Recursion
.... Redox Power
Systems .... Red
Rock
Biofuels .... RedShift BioAnalytics .... Redwood Robotics .... RedZone
Robotics .... RefleXion
Medical .... Refuge Biotechnologies .... Regado
Biosciences
... ReGear Life Sciences ..... ReGen
Biologics ... Regenerative
Medical Solutions ..... Regenerative Sciences ... Regentys
(formerly Asana Medical) .... Regenxbio
....
Regulus Therapeutics ... Rehabtics .... Relay Therapeutics
..... ReliantHeart ....
ReliefBand Technologies ..... Relievant Medsystems
..... Relypsa .... Remedy Plan Therapeutics .... Remedium
Technologies ... RemoteReality .... Rempex
Pharmaceuticals .... Renaissance Services ..... Renegade
Materials .... Reneo
Pharmaceuticals ..... Renerva ..... ReNeuroGen .... Renewable
Alternatives
... Renewable Energy Group .... Renmatix .....
RenovoDerm ..... Renovia .... Renovion .... Renovis ...
Rentech ... Replidyne
...
Repligen .. Replimune Group .... Research Frontiers
.. Research Innovations ..... Resolve
Therapeutics
... Resolvyx
Pharmaceuticals ... Resonetics ..... Respicardia
... Respira
Therapeutics .... Response Genetics
...
Restoration Robotics ..... resTORbio ..... Restore Medical ... Retectix
..... Retek
...Rethink
Robotics ... Retia Medical .... Retriever
Technology
.... RetroSense Therapeutics ..... Reva Medical
... Revance Therapeutics Pharmaceutical ....
Revegen
... ReVision Optics ....
ReVision
Therapeutics .... Revitope Oncology ..... ReVivo Medical
....
RevMedx .... ReVolt Tech
... Revolution
Medicines .... ReWalk
Robotics (Israel) .... Rexahn
Pharmaceuticals
... Rex Computing ..... RF Code ...
RFMicron
.. RFS Pharma ..... RF Surgical.
.... Rgenix .... Rhenium
Alloys .. Rheos Medicines ..... Rheostat
Therapeutics ..... Rheumco .... Rhevision
... Rho ... Rhythm Pharmaceuticals ... Rhythmia
Medical
... Ribometrix ....
RiboNova .... Ribon Therapeutics ..... Rib-X
Pharmaceuticals ... Rice Technology ..... Ridgetop
Group ... Rigel Pharmaceuticals .... RightEye ..... RightHand
Robotics .... Rinat
Pharmaceuticals
.... Rinovum Women’s Health ..... Rio Grande Neurosciences .....
RipCode ... Rite
Solutions .... Ritter
Pharmaceuticals ..... River Vision Development ..... Rive Technology
... RJA Dispersions ... R.L. Phillips ...
RMH
Sciences ...
Robb Surgical Devices .... Robopsy ...
Robotic FX ... Robotics VISION
Technologies ..... Robotic Technology
... Rocket Pharmaceuticals .... Rockwell Medical
..... Rocky Research .... Rodin Therapeutics ... Roka
Bioscience
.....
RoosterBio .... RootPath .... Rosina Food Products ....
Ross Valve ..... Rotational
Medical .... RotoMetrics ..... RoverMed Biosciences ..... Rowbot
Systems .... Royole ..... RQx
Pharmaceuticals .... RRE
Solar ....
Rubicon Tech ...
Rubigo Therapeutics .... Rubitection ..... Rubius Therapeutics ....
RubrYc Therapeutics ..... Rules-Based
Medicine
... Rushford Hypersonic ... Ruud Lighting ..... RxFunction
...
RXi Pharmaceuticals
...
RxMedic .... Rypos
S2 ... Sadasis .... SafeShot .... Saffron
Technology
.... Sage
Electrochromics ... SADAR 3D .... Sage Science ... Sage
Therapeutics ...Sakti3 ... Salarius
Pharmaceuticals .....
Salient Surgical
Technologies
... Salix
Pharmaceuticals ... Salutaris Medical Devices ..... SAM Medical ....
Sancilio
Pharmaceuticals .... Sand 9 .
.. Sandia Biotech .... Sangamo
Biosciences
... Sangart
... Santalis Pharmaceuticals ..... Santarus .... Sanuwave
Health
.... Sapheon .... Sapphire
Energy ....
SARbarcode .... Sarda
Technologies ...
Sarepta Therapeutics .... SatCon
Technology ...
Satori Pharmaceuticals
.... Savara Pharmaceuticals .... Savi ...
SBH
Sciences ...
Scanadu ..... Scholar Rock .... Sciaderm ..... SciClone
Pharmaceuticals
... Sciencescape ..... Scientific
Conservation .... Scientific Research ...
Scientific
Solutions ... Scientific Systems ... SciFluor Life Sciences ... Scilex
Pharmaceuticals .... Scinovia ..... Scioderm .... SciQuest ...
Scopic Software
... Scout Bio .... Scynexis ...
SD Catalyst
Group ... SDL .. SeaChange ...
Seacoast Science
... Seahawk Biosystems ... Seahorse
Bioscience
... Seaside Therapeutics .... Seattle BioMed .....
Seattle
Genetics
...
Seattle Medical Tech .... Sebacia .... Second Genome ....
Second
Sight Medical
Products ... Securboration ..... Secure
Computing ... Sedia Biosciences ..... Seeo
....Segetis ... Seldon
Labs ... Selecta Biosciences
... SELLAS Life Sciences Group .... SeLux
Diagnostics .... Sema4
Natalis
..... Semiconductor
Laser ... SemiProbe ... Semler
Scientific
.... Semma Therapeutics .... Semnur
Pharmaceuticals .... Semprius ... Semprus
BioSciences .... Sencera International ...
SenesTech .....
SenGenix ....
Senior Scientific ..... Seno Medical
Instruments .... Senomyx
... SensAble Technologies ... Sense .... Sense
Diagnostics
....
Senseonics ..... Sensintel .... Sensiotec ...
Sensors
Unlimited
... SensorTran ... Sentelligence
... Senti Biosciences ..... Sentient
Technologies ..... SentreHEART ..... Sepracor
... SeprOx .... SeQual Technologies ... Sequella ...
Sequel
Pharmaceuticals .... Sequenom ... Sequenta ...
Sequent
Medical
.... SeraCare Life Sciences ... Seragon
Pharmaceuticals .... Seraxis ..... Seres Health .... Serenex
... Sermonix
Pharmaceuticals .... Servergy .....
SetPoint Medical .... Seurat Therapeutics ..... Seventh Sense
Biosystems ...
SGB
Biofuels ..... SGX
Pharmaceuticals ...
Shamrock Energy ... Shape Pharmaceuticals ..... Shape Security ....
Shapeways .... Sharklet
Technologies ..... Sharp Edge Labs ..... Shift Labs ..... Shift
Pharmaceuticals ..... Shiloh
Labs ....Shine
Medical Technologies
... Shore
Thing Shellfish .... Shuttle
Pharmaceuticals ..... Si-Bone .... Sicel Technologies ...
SiCortex
... Sideris Pharmaceuticals ..... SI
Diamond Technology .... Sienna Biopharmaceuticals ..... Sierra Energy
..... Sierra Monolithics
... Sierra Nevada ...
Siga Technologies ...
SiGe Semiconductor ... Sigilon Therapeutics ....
Sigma Labs
(NM) .... Sigma
Technologies .... SignalFX (formerly Signal Fuse) ..... Signal Genetics
.... Signature
Genomic Laboratories
... Sila Nanotechnologies .... Silarus Therapeutics
.... Silatronix ..
Silent
Power ... Silicon Biosystems Menarini ..... SiliconBlue
....
Silicon Laboratories ...
Silicon
Mountain
Design .. Silicon Space Technology .... Silk .... Silk Tech ....
Siluria ...
Silverbrook
... Silverback ..... Silvergate Pharmaceuticals .... Silver
Spring Networks
... Simbol Materials ... Simply Incredible Foods ... SiMPore
...
Simulation
Technology and Applied Research ... Simulution
... Singlera Genomics ..... Singulex ... Sinmat
... SiNode Systems .....
Sintact Medical Systems
..... Sion
Power
... SiOnyx ... Sioux Manufacturing ...
Sirga Advanced
Biopharma .... Sirion Therapeutics ...
Sirnaomics ..... Sirna
Therapeutics ... Sirtris Pharmaceuticals ... Sisu Global
Health
..... Sitari Pharma .....
Skybox Imaging .... Skyhawk Therapeutics ..... Skyline Medical
....
Skyonic
... SLI .. SLIPS Technologies .....
SmartCells
... Smart Modular
Technologies ... SmartSpark Energy Systems ...
Smart
Structures .... Smart Wires ..... SmartZyme BioPharma ....
Smisson-Cartledge Biomedical ...
Smooth-Stone
...
SNP Bio ..... Socrates Health Solutions .... Soft Machines
....
Soft Robotics ..... SoftSwitching
Technologies
... Soft Tissue
Regeneration ... Soladigm (now View) ..... SolAero
Technologies ..... Solaicx ....
Solais Lighting
....
Solana Surgical ..... SolaranRx ..... SolarBridge
Technologies ... Solar Connection ....
Solarea .....
Solaria ...
Solarmer
Energy ...
Solar Power Technologies ... SolarWinds
... Solazyme
... Solexant ... Solexel ... SolFocus ... Soliant
... Solid Biosciences .... Solid Concepts ..... SolidEnergy
....
Solidus Biosciences
..... SolidWorks
... Soliris .... Soliton ..... Solixia
... Solix
Biofuels
... SolMap
Pharmaceuticals ... SoloHealth ... Solomon
Technologies
... Solo Power .... Solstice Biologics .... Soluble Therapeutics ....
Solx ....
Solyndra ... Soma .... SomaLogic .... Somatic Labs
..... Somaxon
Pharmaceuticals ....Somna Therapeutics ...
Sonalysts ...
Soneter .... Sonex Aircraft ... Sonitus Medical
... Sonivate ..... SonoSite
... Sonovex .... Sontra Medical ... Sonus
Pharmaceuticals
...
Sophiris
Bio .... Sophono ..... Soraa .... Sorrento Therapeutics ....
Soteira
... Sostena .... Sotera Wireless ... Sound Pharmaceuticals
.....
Sourcefire
... Source MDx
... Southwall Technologies ... Southwest Windpower
...
Space Dev ...
Spaltudaq ... Spansion .... Sparkbuy ..... SparkCharge .... Spark
Therapeutics ....
Sparo Labs .....
Spatial Photonics
...
SPEC ..... Spectra254 .... Spectragenetics .... Spectral Energies .....
Spectral
Systems .....
Spectranetics ...
SpectraWatt ... Spectro Coating ... SpectrumS4 ....
Speech
Tails ... Speer Medical .... Spero Therapeutics ..... Spinal
Modulation ..... Spinal
Restoration
... Spinal Simplicity ..... Spinal
Stabilization Technologies ..... SpineEX .... SpineGuard ...
Spineology
... Spine Wave .. Spintech .... Spin
Transfer
Technologies ....
SpiralGenetics .... Spiral Therapeutics .... Spiration
... Spire
... Spirox (formerly Nasoform) ..... Spoonflower .... Spotfire ... Spot
On Sciences ...
Spredfast
... Spring Bank Pharmaceuticals ... SpringLeaf Therapeutics
... SpringWorks Therapeutics .... SPR Therapeutics
.... Spyrix ....SQZ
Biotech ..... SRL ... Staktek Holdings ... Standard
Bariatrics .... STAR Cryoelectronics
... Starfire ... Startech Environmental
... Startup Circle Pharma .... StarVision
Technologies .... Stasys Medical ..... SteadyMed Therapeutics
..... Stealth
Therapeutics ... Steel City Optronics ....
Stellaray
.... Stellar Biotech .... Stellar Science ....
Stellent .... Stemagen ... StemBioSys .... Stem Cell Assurance (Now
BioRestorative Therapies) .... StemCells
... Stemcentrx ..... StemCo
Biomedical ... Stemgent ...
StemImmune ....
Stemina Biomarker
Discovery ... Stemonix ..... Stem Pharm .... Stereotaxis ...
Sterilmed ...... Sterling
Semiconductor ..... StimMed ..... Stirling Energy .... Stoke
Therapeutics ..... Stottler
Henke ... Straight Flight .... Stratagene ... Strata Oncology
..... Stratasys
... Stratatech
... Strategic Response Initiatives .... Stratos
Genomics
... Stromedix .... Strongbridge
Biopharma .....
Sucampo Pharmaceuticals ..... Summit
Technology
.... Sun BioPharma ..... Sun Catalytix
.... Sunesis
Pharmaceuticals
.... SunHealth Solutions ... Suniva ....
Sunovion
Pharmaceuticals
... SunPower ... Sun Power Biodiesel ...
Sunrise
Ridge Algae ....Sunshine Heart .... Suntech ...
Suono ..... Superconductive
Components ... Superconductor Technologies ... SuperDimension ...
SuperFlex ..... Superior
Organoid Technologies ..... Supernus
Pharmaceuticals .... SuperPower ... Superprotonic
.... SupraSensor .....
Surefire
Medical
.... Surface
Logix
... Surface Oncology ..... Surgient ...
SurgiQuest
.... Surmet
... SurModics ... Suros Surgical Systems
..... Surrozen .... SURVICE Engineering ..... Sustainable Oils ....
SustainX ... Sutro Biopharma ..... Sutron .....
SutroVax ..... SuturePro
Technologies (now Ceterix) .... SuviCA .... SuVolta ... Suzlon Rotor
... SVS
... SPEC ... Swallow Solutions .... SweetSpot Diabetes Care
... Swift Biosciences .... Syagen Technology
... Symbiomix Therapeutics ..... Symbiont Web
...
Symbotic ...
Symetrix .... Symic Biomedical ..... Symyx
Technologies
... Synack .... Synageva BioPharma ... SynAm Vaccine
....
SynapDx
....
Synaptics ... SynCardia Systems ..,.. Synchroneuron ....
SynchroPET .... Syndax
Pharmaceuticals
... Syndexa Pharmaceuticals .... Synedgen ....
Synergy
Biomedical
....
Synergy Pharma ..... SynGen .... Synlogic ..... Synopsys .... SynSonix
.... Synta
Pharmaceuticals ... Syntax-Brillian ... SyntheMed
... Synthetic Biologics ..... Synthetic Genomics
.... SyntheZyme .....
Synthorx ....
Syntimmune ..... Syntrix
Biosystems .... Syntronics .... Synvitrobio ..... Syros
Pharmaceuticals .... Sysgain .... Syslogic .... Systagenix Wound
Management .....
Systems and Processes Engineering
SPEC ... Systima Technologies ..... Sytera
T2
Biosystems ... T3D Therapeutics ..... Tabula ... Taconic
BioSciences ..... Tactical Engineering and Analysis ..... Tactile
Systems
Technology .... Tactiva Therapeutics ..... TAI Diagnostics .....
Talecris Biotherapeutics
... Taligen Therapeutics
...
Talima Therapeutics ... Tal Medical ... Talon Therapeutics
... Tandem Diabetes Care ...
Tangen Biosciences
..... Tango
Therapeutics ..... Tanox ..Tantaline
.... TapImmune .... Tarari ...
.Targacept ...
TargeGen
... Targ-Anox ... Targanta
... Targazyme (formerly)America Stem Cell....
Targeson
... Targeted Genetics ... Targeted Growth
... Taris Biomedical .... Tarveda Therapeutics
..... Tascent .... Tauriga
Sciences
.... Taxa Biotechnologies ..... Taxon
Biosciences .... Taxus
Cardium (formerly Cardium Therapeutics) ... Taylor
Devices ..... TCR² Therapeutics ..... TDA
Research .... Tealium ..... TearScience
...
Tech-X .... Techniscan Medical Systems
... Technology
and Devices Int'l ... TechTol Imaging ... TELA Bio .....
Telecardia ...
TeleContinuity ... Telefactor ..... Telemedicine
Up Close operates as DxUpClose ...... Telik ... Tempest
Therapeutics ..... Templex
Technology... Tempus ..... Tenax Therapeutics .... Tenaya
Therapeutics ..... Tendril
...
Tendyne
Holdings ..... Tensha Therapeutics ...
Tepha
... TeraDiode .... TeraDiscoveries (now Cloud
Pharma) ....
Terapio ... TeraStor ...
Terrabon ...
Terrajoule ... TerraMetrics ... Terumo BCT .... Terus
Technologies .... TESARO ....
TeselaGen
Biotechnology .... Tessera
Technologies ... Tethys BioScience .... Tetra
Discovery
Partners .... Tetragenetics
... TetraLogic Pharmaceuticals ...
Tetraphase
Pharmaceuticals ... TetraVue ... Tezzaron
Semiconductor .... TFF Pharmaceuticals .... TGS Knee Innovations
... TG Therapeutics .... Thar Pharma .... Thalchemy ..... The
ExOne .... The Medicines ..... Therabron Therapeutics ..... Theraclone
Sciences
...
Theragenics
.... Therametric Technologies ... Theranos
....
Therion
Biologics ... Thermacore ... Thermage
...
Thermal Gradiant .... Thermal Spray Technologies
....
ThermalTherapeutic Systems
... Thermedical ...
ThermoAura ....
ThermoCeramiX .... ThermoGenesis .... Thermon ... TherOx ....
Thesan
Pharmaceuticals .... Theseus...
Thetis Pharmaceuticals ...
ThingMagic... Third Wave Technologies .. Thoratech
Tech
... Thorley Industries .... ThreeRivers 3D ..... Threshold
Pharmaceuticals ...
ThromboVision .... Thyritope Biosciences
.... Tiax
...
Tibbetts Industries
... Tibion ..... Tiburio
Therapeutics ..... Tilera ...
Tillges
Technologies ... Tioma Therapeutics ..... TissueGene ..... TissueLink
... Tissue Regeneration Systems .... Titan
Pharmaceuticals .... Titan Spine ..... TJ Technologies .... TLC
Precision Wafer
... Tmunity Therapeutics .... Tobira Therapeutics ....
Tocagen
...
Tokai Pharmaceuticals .... Tolerx .... TomoTherapy
... Tone Tree ..... Topia Technology .... TopicalRemedy ....
Topokine Therapeutics
.... Torax
Medical ... Torque Therapeutics ..... Total Immersion
...
TotipotentRx .... Totus Solutions .... TP Therapeutics ..... Trace
Genomics ..... Tracon
Pharmaceuticals
... TranS1
.... Transatomic Power .... Transcend Medical ...Transcept
Pharmaceuticals
.... TransCorp
..... Transcriptic ..... TransEnterix ... Transgenomic
...
Translattice
.....
TransMedics
... Transmeta ... TransMolecular
... Transphorm .....
TransTech
.... TransTech Pharma (now vTv Therapeutics) ... Transzyme
Transzyme Pharma ... Traverse
Biosciences ... Traycer
Diagnostic Systems ..... Trellis
Bioscience
... Trellis Earth Products ...
Trevena
... Trevi Therapeutics ..... Trex Enterprises ... Triad
Semiconductor .... Tri Alpha
Energy ..... Triangle
BioSystems .... Tribogenics
....
Tribologix
.... Trice
Orthopedics .... Tricida ..... Trident Systems ... Trilumina ....
Trimble Navigation
.... Trimeris
... Triquint
Semiconductor ...
Triton Systems ... Trius Therapeutics ...
TriVascular
Technologies .... Trovagene ..... Trubion
Pharmaceuticals ... Tru-D SmartUVC ..... True Diagnostics
....
True Health Diagnostics
.... True North Therapeutics .... Truestone ..... TruTouch Technologies
..... Try Eco ..... Tryton
Medical
... Tularik .... Turtle Mountain
Communications .... TVA Medical
... Tvardi Therapeutics .... Twelve .... Twentyeight-Seven
Therapeutics ...... Twin Star Medical ... Twist
Bioscience
..... TwoXAR ..... Tyme Technologies .... TypeZero Technologies ....
Tyrosine
Pharmaceuticals
....
Tyrx
uBiome .... UCAN ... UES
... Ulthera .... UltraCell ... Ultragenyx
....
Ultralife Batteries
...
Ultramet... Ultradian
Diagnostics ..... Ultraviolet Sciences ... Unbounded Robotics
.... Unchained Labs .... UNIAX
... Unica
... Unidym ... UniEnergy Technologies ..... Unified
Nexsys
.... Unilife ..... Uni-Pixel .... Uniqure
.... United
Devices ... United
Therapeutics
... United Therapies ..... Unity Biotechnology .... Universal
Cells ...... Universal
Display ... Universal
Robots ..... Universal
Technical Resources .... Universal
Technology .... Unleash Immuno
Oncolytics ..... Unum Therapeutics .... Unwired
Nation ... Uptake Medical
... UQM Technologies ... Urbix Resources ....
Urigen
Pharmaceuticals
.... UroGene Pharma ..... US
Nanocorp ... Uroplasty ..... US Bioscience ..... US
Silicones ... UTC Power .... Utilidata ... Utron
.....
UVision360
Vaccinex ..... Vaccinogen .... Vader Systems .....
Vala
Sciences
....Valencell ... Valence Technology .... Validity
Sensors
... Valmont Industries .... Vanda Pharmaceuticals
... Vanguard Space Technologies ..... Vapogenix ..... Variant
Pharmaceuticals ..... Vascudyne ..... Vascular
Biogenics (also VBL Therapeutics) .....
Vascular
Designs ... Vascular Genesis ..... Vascular Pathways
...
Vascular Pharmaceuticals ....
Vascular Solutions .....
Vasculox .... VasoGenix
Pharmaceuticals ... Vasoptic Medical ..... Vast Therapeutics
.... Vativ
Technologies ... Vaxart ... Vaxess
Technologies ....
VaxGen
...
VaxInnate ... vCalc .... Vecna Tech ...
Vectorlogics
....
Vedanta
Biosciences
.... Veeva Systems .... Veezyon
... VeinAid ... Velano Vascular .... Velicept
Therapeutic
..... Velocimed ...
Velomedix
... VelosBio ..... VenatoRx Pharmaceuticals ..... Venaxis
..... Vendormate
....
Veniti ... Vensun
Pharmaceuticals ....
VentiRx
...
Ventria Bioscience
... Ventrix ..... Ventrus
Biosciences ... Veracode
... Veracyte
... Veran Medical Technologies ..... Verastem
... VeraSun Energy
... VerAvanti .... Verax
Biomedical ... Verdezyne ... Vergent Bioscience .....
VerinataHealth ...
Verenium ... Vericel (formerly Aastrom Bio) .... Verifica-BG
... Veritas Genetics .....
Vermillion .... Vermont
Composites ...Veros Systems ... Verrica Pharmaceuticals .... Versar
.... Versartis ...
Vestagen
Technical
Textiles .... Vestaron .... VerteCore ..... VerteraSpine ..... Vertex
Pharmaceuticals ... VeruTEK Technologies ... Vesper
Medical
..... Vextec
... VGBioCogCubed .... V-Glass .... VGo
Communications ... VGX Pharmaceuticals ..... ViaCell
... ViaCyte
.... Viacor
.... Viamet Pharmaceuticals
... ViaSat
... Via Separations .... Vical . .. Vicarious .... Vicus Technologies
.... Vidacare
... View ..... Viking
Therapeutics .... Vion
Pharmaceuticals
... ViraCor Laboratories ... Viracta Therapeutics ..... Viral
Genetics ....
Virdante Pharmaceuticals ...
Virdia
.... Virent Energy Systems ... Viresco Energy
... Virobay .... ViroPharma . .. ViroXis ...
Virtify .
VirtualScopics
.... Virtusa
... Viscardia ..... VisEn Medical ... VisiGen
Biotechnologies
... VisionGate ..... VisionQuest ..... Vision-Sciences
... Vistagen
Therapeutics ... Vistec
Lithography ... Visterra ...
Visualase .... Vitae Pharmaceuticals ..... VitalMedix
... Vital Therapies ...... Vital Vio .... VitaPath Genetics
... Vitriflex .... Vium ..... Vivex Biomedical
.... Vividion Therapeutics ..... Vivisimo .... Vixar
... Vixel ... Vixiar Medical ..... Vizzario .... Vlingo
... VLST ..... VMware ... Voci Technologies .... Volcano ....
VoltServer ... VORAGO Technologies (previously Silicon
Space Technology) ..... Vorbeck Materials
... Vor BioPharma ..... Vortex Biosciences ..... Vortex
Medical
... Voxel
.. voxeljet ..... Voyager Therapeutics
.... Vtesse ....
VT
Silicon
.... vTv Therapeutics (formerly TransTech Pharma) ..... VUV Analytics
.... Vuzix .... Vyriad .... Vyrx
Pharmaceuticals ..... VytronUS
WaferGen
Biosystems ...
Wakonda Technologies ... Walker Magnetics Group ...
Waste2Watergy
.... Waveband
..... Wave Computing ..... Waveguide ..... WaveRx ... Weinberg Medical
Physics .... WellStat
Therapeutics .... Whole Biome ..... Whole
Trees
.....
WiBotic .... Wicab ..... WildcatDiscovery .... Wiliot .....
Willow Garage
...
Wilocity
.... Wilson
Greatbatch
.. Wilson Tool International .... Wilson Wolf Manufacturing
...
WiMax.com ...
Windlift ... Windtree
Therapeutics ..... WinSanTor .... Wintegra ... WISErg .... Wizbe
Innovations ...
WMR
Biomedical (now Arsenal Medical) ... Wolf Technical
Services ... WoundZoom .... Woven Orthopedic Technologies
....
Wright Materials Research
... Wright Therapy Products ..... W Solar
Group
X4 Pharmaceuticals ..... Xanofi ... Xanthus
Pharmaceuticals
... XBiotech USA ..... X-Body Biosciences
... Xcede Technologies ..... XCELL BIOLOGIX .....
Xcell Biosciences
....
Xcellerex ... XChanger
Companies .... Xencor .... X-energy ..... Xenetic Biosciences ....
Xenex
Disinfection Services .... Xenex
Healthcare Services ... XenoGen Biosystems .... Xenomics
... Xenoport ... Xeris
Pharmaceuticals ... Xetrios Therapeutics .... XF
Technologies .... xG Technology .... Xidex ... Xitronix
... XL
Hybrids ... Xlumena .... Xoc Pharmaceuticals ..... Xollai ...
Xolve
(formerly
Graphene Solutions)
... Xoma
... XProSciences (now Icagen) ..... X-Ray Optical .... X-Spine
.... XSunX
...
Xtalic .. Xtant Medical
Holdings ..... Xtent ...Xtreme Power
... XTuit Pharmaceuticals ....
Xunlight .... XyloCor Therapeutics .... Xynomic
Pharma
Yan Engines ... Yardney Technical Products .... Y-Carbon ... Yulex .... Yumanity Therapeutics .... Yurie
Z ... Zacharon Pharmaceuticals .... ZafGen .... Zavante Therapeutics ..... ZBB Energy ... ZeaChem ... ZeaKal .... Zebra Imaging .... Zebra Medical Vision (Israel) ..... Ze-gen ... ZenBio ... Zenomics .... Zenverge ..... Zeo .... Zephyr Technology ... ZeptoMetrix .... ZeroFOX .... Zero Locus .... Zero Mass Water .... ZetaRx Biosciences .... Zilker Labs ... Zinc Matrix Power ... Zintera ..... Ziopharm Oncology ... Ziptronix .... Zogenix ... Zosano Pharma ... ZPower ... ZS Genetics ..... zSpace ..... ZS Pharma ... ZSX Medical .... Zumobi ... Zunum Aero ..... Zurex Pharma ... Zwitter Technology .... Zyga Technology .... Zygo ... Zymergen ..... ZymoGenetics ... Zynerba Pharmaceuticals .....Zymeworks ..... Zyomyx ... Zystor Therapeutics ... Zyvex Technologies