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Carl Nelson Consulting

phone 202-841-1914carl@carl-nelson.com SBIR for high tech innovators

Hark,What News?

news and views for entrepreneurs .....as of Sep 17, 2019

Note: Carl Nelson Consulting, Inc is not an investment adviser and may hold a financial interest or client relationship in companies discussed. Looking for older stories? Visit the archives

H. Lundbeck A/S (Denmark) and Alder Pharmeuticals (Bothell, WA; one SBIR) up 84% [Sep 16, 19] committed to transforming migraine treatment and prevention announced a definitive agreement for Lundbeck to acquire Alder. ... transaction is valued at up to $1.95 billion (approximately DKK 13 billion) net of cash, on a fully diluted basis. [joint companies press release, Sep 16, 19]

Novavax up 20% [Sep 16, 19]

Stereotaxis (St Louis, MO; one SBIR in 1992) up 16% [Sep 16, 19]

Karyopharm Therapeutics announced a royalty agreement with HealthCare Royalty Partners for up to $150 million to support the ongoing development and commercialization of XPOVIOTM (selinexor), the Company’s first-in-class, oral SINE compound, which is currently marketed in the U.S. for the treatment of patients with heavily pretreated multiple myeloma. [company press release, Sep 16, 19]

II‐VI announced that it signed a strategic partnership agreement with LITE-ON Technology, a global leader in optoelectronic components, to partner in the volume manufacturing and commercialization of packaged semiconductor lasers for mass-market light detection and ranging (LiDAR). [company press release, Sep 12, 19]

AgeneBio (Baltimore, MD; no prior SBIR, approx $26M NIH grants, founded 2008) has been awarded nearly $500,000 from the Alzheimer’s Drug Discovery Foundation and has been selected to receive a [NIH] SBIR of up to $2.9 million Both awards go towards the development of a first in class therapeutic in AgeneBio, Inc.’s GABA-A a5 program [company press release, Sep 11, 19] prior funding $10M [crunchbase.com]

Tariffs as politics. President Xi Jinping and top Chinese officials have signaled their willingness to accept some pain at home under U.S. tariffs rather than agree to major concessions. China experts say the political cost to Xi of yielding to Trump could be more damaging than living with the tariffs as Xi seeks to solidify his power in the Communist Party while expanding influence over the world economy (The Hill). World's biggest economy spars with world's biggest population.

10X Genomics (Pleasanton CA; no SBIR, founded 2012) up 35% [Sep 12, 19] after $390M IPO. prior funding $242M [crunchbase.com]

Prevail Thera up 17% [Sep 12, 19]

Evelo BioSciences up 17% [Sep 12, 19]

Tocagen (San Diego, CA; $500K SBIR) down 77% [Sep 12, 19] announced that the Toca 5 Phase 3, randomized, multi-center clinical trial evaluating Toca 511 & Toca FC in patients with recurrent high grade glioma (HGG) undergoing resection missed the primary endpoint of overall survival compared to standard of care treatment (11.1 months median compared to 12.2 months, HR=1.06, p=0.6154). In addition, all secondary endpoints showed no meaningful difference between the arms of the trial. The safety, tolerability and adverse event profile of Toca 511 & Toca FC was as expected for this patient population. [company press release, Sep 12, 19]

Catalyst Pharma down 17% [Sep 12, 19]

I am enough of an artist to draw freely upon my imagination. Imagination is more important than knowledge. Knowledge is limited. Imagination encircles the world. [Albert Einstein, 1929]

Nido Biosciences (Boston, MA; no SBIR) raised $4M in equity, according to an SEC filing (Rowan Walrath, BostInno, Sep 11, 19].

Yes today, no tomorrow. President Trump told his advisers that he doesn’t plan to try to bypass Congress and lower capital-gains taxes by indexing gains to inflation, according to three people familiar with the matter. [Wall Street Journal, Sep 11, 19] More important, who would invest where government policy and leaders change at the whim of the executive? Trump disdains our stable government structure wherein law determines the policies and Congress approves the Executive Branch leaders.

Acorda Thera up 27% [Sep 10, 19]

Immunomedics up 17% [Sep 10, 19]

Arcadia Biosciences (Davis, CA) said it raised $9.2 million from a direct offering of its stock to institutional and accredited investors. [Mark Anderson, Sacramento Business Journal, Sep 10. 19]

The Alzheimer's Drug Discovery Foundation (ADDF) has awarded $500,000 to AgeneBio (Baltimore. MD; at least $3M SBIR) to accelerate the first-in-class therapeutic to the clinical stage $2.9 million over 3.5 years from the National Institute on Aging (NIA), adding to the ~$11M of prior NIH investment in this innovative therapeutic program provided through the NIA's AD Drug Development Program and the NIH Blueprint Neurotherapeutics Program. [company press release,, Sep 11, 19]

Holos (Madison, WI; founded 2015) software startup just landed its second contract from the U.S. Air Force to make virtual reality and augmented reality training programs. Holos announced that it has received a $750,000 Phase II SBIR contract with the Air Force. Holos said it will help the Air Force develop VR maintenance and repair training programs. It will also develop a prototype for the Air Force’s Multi-Domain Command Control system. Holos creates VR and AR education software for classrooms, giving teachers and students the ability to create, organize and learn in 3D. For its Air Force applications, the technology is largely the same, but loaded with different content, the company told Wisconsin Inno earlier this year. Holos likens its product to a 3D version of Powerpoint. [Jim Dallke, WisconsinInno, Sep 5, 19] What's the SBIR problem here: What is SBIR for? Like almost every software contract, the contractor can certainly do what it proposes: a sound engineering job by competent engineers. The bureaucratic question for software SBIR is not technical mysteries, but will anyone buy the product - a question best left to ordinary investment and R&D programs. But with agency authority to fund any R&D thing they want with SBIR, mission agencies chose utility while both agency and company claim innovation.

Advisors beware. Regardless of who has advised Mr. Trump on foreign affairs — generals and corporate tycoons, seasoned pros and amateurs — all have proved powerless before a zest for chaos that would have thwarted George Marshall. [NYTimes ediotrial, Sep 11, 19] Trump Rule: When I want your opinion, I'll tell you what it is. Trump will have trouble finding a Kissinger for his Nixon, because as David Graham (WashPo) notes: The problem is not that Trump failed to get along with John Bolton—it's that he doesn't want a national security adviser in the first place.

ACADIA Pharma up 63% [Sep 9, 19] announced that its Phase 3 HARMONY study, a double-blind, placebo-controlled relapse prevention trial evaluating pimavanserin for the treatment of dementia-related psychosis, met its primary endpoint, demonstrating a highly statistically significant longer time to relapse of psychosis with pimavanserin compared to placebo in a planned interim efficacy analysis. [company press release, Sep 9, 19]

Cesca Thera up 17% [Sep 9, 19]

Ardalyx up 15% [Sep 9, 19]

Frequency Therapeutics (Woburn, MA; no SBIR) biotech focused on degenerative diseases, filed to raise $100M in an IPO. It has yet to post a revenue and posted losses of $19.2M last year [Srividya Kalyanaraman, BostonInno, Sep, 9, 19]

Aprea Therapeutics (Boston, MA ans Sweden; no SBIR) biotech focused on cancer therapies, filed to raise $86M in an IPO. It has yet to post a revenue and posted losses of $15.5M in 2018 [Rowan Walrath, BostonInno, Sep, 9, 19]

Platelet BioGenesis (Cambridge, MA; no SBIR) which develops stem cell-derived, on-demand human platelets and platelet-based therapeutics, closed more than $26M in Series A-1 financing. [Rowan Walrath, BostonInno, Sep, 9, 19]

Bio2 Technologies (Woburn, MA; no SBIR) raised about $4.3M as it continues with a clinical trial of its Vitrium resorbable orthopedic biomaterial for musculoskeletal surgery. It seeks to raised about $2.2M more, according to an SEC filing. [Srividya Kalyanaraman, BostonInno, Sep, 9. 19]

Biotech startup Trucode Gene Repair (South San Francisco, CA; no SBIR) announced that it is advancing its next-generation in vivo gene editing technology to correct mutations that cause sickle cell disease, cystic fibrosis, and other devastating genetic disorders. With $34 million from investors, Trucode has now emerged from stealth-mode after establishing a broad and exclusive intellectual property estate for its triplex gene editing technology, assembling a cohesive team of industry veterans, and identifying lead candidates in multiple clinical indications. [company press release, Sep 10, 19]

Plant science company ZeaKal (San Diego, CA; no SBIR, founded 2010) said it closed a $15 million Series C financing round to advance its PhotoSeed technology, which increases crop yield by increasing a plant’s capacity for photosynthesis. [Sarah de Crescenzo, xconomy.com, Sep 10, 19]

Vical (San Diego, CA; $13M SBIR, founded 1987) stockholders late last month OK’d a reverse merger with Brickell Biotech (NASDAQ: BBI). ... was developing treatments for life-threatening infectious diseases, including antiviral and antifungal compounds, announced in June that it planned to become part of Brickell (Boulder, CO; no SBIR) developing drugs for skin diseases. [Sarah de Crescenzo, xconomy.com, Sep 10, 19]

Microbot Medical (Hingham MA; no SBIR) up 44% [Sep 6, 19] will demonstrate a working prototype of the Company's Self-Cleaning Shunt (SCS(TM)). [company press release, Sep 5, 19]

Applied Genetic Technologies up 17% [Sep 6, 19]

Phase BioPharma down 19% [Sep 6, 19]

Plus Thera down 15% [Sep 6, 19]

OpGen is acquiring German molecular diagnostic company Curetis in a move that will create a combined firm worth $24M. OpGen, a precision medicine developer, will make Curetis a wholly owned subsidiary [DCInno, Sep 5, 19]

Adaptive BioTech down 17% [Sep 5, 19]

Plus Thera down 16% [Sep 5, 19]

Veralox Therapeutics (Frederick, MD; $300K SBIR, founded 2017) a preclinical stage company focused on accelerating the development of first-in-class therapeutics for unmet medical needs, announced it has raised a $5.4 million seed funding round. [company press release, Sep 5, 19]

OpGen up 23% [Sep 4, 19]

Immunic down 17% [Sep 4, 19]

Ardelyx down 15% [Sep 4, 19]

Repare Therapeutics (Cambridge, MA and Canada; no SBIR) raised an $82.5 million series B round to take synthetic lethality drugs into humans. [company press release, Sep 4, 19]

Vertex Pharmaceuticals announced a definitive agreement under which Vertex will acquire Semma Therapeutics (Cambridge, MA; no SBIR), pioneering the use of stem cell-derived human islets as a potentially curative treatment for type 1 diabetes, for $950 million in cash. [Vertex press release, Sep 3, 19]

Selecta Biosciences (Watertown, MA; $200K SBIR, founded 2007) raised $5.8M in equity, according to an SEC filing. [Srividya Kalyanaraman, BostonInno, Sep, 4. 19]

Sofregen (Medford, MA; no SBIR) raised $8.1M in equity, according to an SEC filing. [Srividya Kalyanaraman, BostonInno, Sep, 4. 19]

Curamir Therapeutics [Woburn, MA; no SBIR) raised $5.2M in equity and seeks to raise an additional $5M, according to an SEC filing. [Rowan Walrath, BostonInno, Sep, 4. 19]

Ardelyx (Fremont, CA; no SBIR) up 71% [Sep 3, 19], a specialized biopharmaceutical company focused on developing first-in-class medicines to improve treatment for people with cardiorenal diseases, reported positive results from AMPLIFY, a pivotal Phase 3 study of tenapanor in combination with phosphate binders in patients with chronic kidney disease (CKD) on dialysis whose hyperphosphatemia was not previously controlled with binders alone. [company press release, Sep 2, 19] total funding $300M [crunchbase.com]

Liquidia Tech down 19% [Sep 3, 19]

Mirum Pharmaceuticals down 21% [Sep 3, 19] reported financial results for the quarter

PhaseBio Pharmaceuticals down 15% [Sep 3, 19]

drug developer Viela Bio (Gaithersburg, MD; SBIR) filed to go public with a $150M IPO, just more than a year after spinning out from MedImmune. [Kieran McQuilkin, DCInno, Sep 3, 19]

Uncoupling. Instead of giving in to Mr. Trump’s demands, Huawei recently introduced its own operating system, Harmony, an alternative to Android that will reduce Huawei’s reliance on U.S. technology. ...the president’s erratic approach has aggravated the situation by encouraging Mr. Xi to embrace decoupling on his own terms. [Stephen A. Myrow, Wall Street Journal, Sep 3, 19] Meanwhile, President Trump said that Chinese manufacturing would “crumble” if the country did not agree to the United States’ trade terms, as newly released data showed his trade war was washing back to American shores and hurting the factories that the president has aimed to protect. [Ana Swanson, New York Times, Sep 3, 19] Trump marches boldly at the head of the America Alone parade, apparently without looking over his shoulder to see who is following.

Tax cuts were once critical to the Republican Party’s electoral success. Now, polling data show that few Americans believe taxes are the most important issue facing the nation. [Jackson Gode and Vanessa Williamson, Brookings, Sep 3, 19] Which means that Trump and the Republican Congress got away with their tax cuts for the wealthy, nothing for the middle and lower echelons, and a big national debt increase, all justified by a fantasy supply-side economics argument. Now the Republicans will shift back to the case for cutting public spending benefitting the undeserving unwealthy.

OpGen (Gaithersburg, MA; no SBIR) up 18% [Aug 30, 19]

Sonavex (spun out of Johns Hopkins, Baltimore. MD; $1.2M prior SBIR) medical device company announced a $3 million [NIH] Phase II SBIR to use its EchoMark & EchoSure devices to support arteriovenous (AV) fistula maturation and long-term viability. ... for prospective clinical studies and continued [R&D]. [company press release, Aug 29, 19] prior funding $10M [crunchbase.com]

Agilvax (Albuquerque, NM; $2.6M SBIR, founded 2011) raises millions, names new CEO [Albuquerque Business Journal, Aug 29, 19] prior funding $8M [cruchbase.com]

A team led by Dynetics (Arlington, VA and Huntsville, AL; at least 30 SBIRs) technical solutions business will develop prototypes of the Common-Hypersonic Glide Body system under a potential three-year, $351.6M other transaction agreement with the U.S. Army. Dynetics said it will work with Lockheed Martin, Raytheon, and General Atomics’ electromagnetic systems business on the C-HGB prototype development project. [Jane Edwards, GovConWire, Aug 30, 19]

There are twice as many workers over age 60 as there are under 30. [Courtney Buble, GovExec, Aug 30, 19] Fresh blood needed; please ignore the current President's rantings and sign up for the long haul of successive presidents and reasonably stable laws.

Is nothing sacred? President Trump appears to have taken the highly unusual step of releasing an official and relatively high resolution annotated U.S. intelligence image. [New York Times, Aug 30, 19] A gift for all those enemies out there who did not know how good our satellite vision is. Yet simultaneously excoriating an FBI head who sought outside advice about sensitive but unclassified information in a difficult political situation. The bottom line: who is not with me is against me.

Who me, wrong? President Trump rejected the notion that his trade policies were having a negative impact on the U.S. economy, instead blaming “badly run and weak companies” for any business setbacks. [Wall Street Journal, Aug 30, 19]

LogicBio Therapeutics (Cambridge MA; no SBIR) up 29% [Aug 29, 19]

Esperion (Ann Arbor, MI; no SBIR, founded 2008) announced positive top-line results from the Phase 2 bempedoic acid / ezetimibe combination tablet study (1002-058). This was a randomized, double-blind, parallel group study assessing the efficacy and safety of the bempedoic acid / ezetimibe combination tablet compared to ezetimibe and placebo in 179 patients with both hypercholesterolemia and type 2 diabetes. Patients enrolled were on stable background diabetes medications and washed out of lipid modifying therapies. [company press release, Aug 29, 19] total funding $245M [crunchbase.com]

Zogenix, a global pharmaceutical company developing rare disease therapies, announced that it has entered into a definitive agreement to acquire Modis Therapeutics (Oakland, CA; no SBIR, founded 2016) biopharmaceutical focused on developing novel therapies for rare genetic diseases with high unmet medical need. Modis’slead product candidate, MT1621, an investigational deoxynucleoside substrate enhancement therapy,is in late-stage development for the treatment of Thymidine Kinase 2 deficiency (TK2d) .... Modis will receivean upfront payment of $250 million, comprised of $175millionin cashand $75 million in Zogenixcommon stock. Modis is also eligibleto receive additional milestone payments consisting of $100 million upon receipt of [FDA] napproval of MT1621in the U.S. and $50 million upon European Medicines Agencyapproval in Europe. Zogenix will also paya5%royalty on any future net salesof MT1621. [Zogenix press release, Aug 29, 19] Modis $30M Series A in 2018

Not leaving China. according to a survey of U.S.-China Business Council members, 87% said they neither have moved nor plan to shift operations out of China, compared with 90% in a 2018 survey. Only 3% said their China operations were unprofitable, unchanged from a year ago. [Jenny Leonard, Bloomberg News, Aug 29, 19]

Reversal. The .gov now says that children born to US military and USG employees overseas will still be automatically US citizens if the parent is.

Plus Therapeutics up 29% [Aug 28, 19]

PhaseBio Pharma up 17% [Aug 28, 19]

Ionis Pharma (Carlsbad, CA; at least $4M SBIR) announced that GSK exercised its option to license Ionis' antisense medicines for people with chronic hepatitis B virus (CHB) infection following positive Phase 2 results. CHB is a chronic viral infection of the liver that can lead to significant and potentially fatal health conditions, including cirrhosis, liver failure and liver cancer. Current treatments for patients with CHB provide low levels of hepatitis B virus S antigen seroclearance, leaving many patients without a treatment to achieve sustained disease remission. There are more than 200 million patients worldwide living with CHB. [company press release, Aug 27, 19]

Slippery Slope. Trump said he'll pardon U.S. government employees who break laws [seize private land and disregard environmental rules] while working on border barriers, the Washington Post reports. [Defense One, Aug 28, 19]

Miromatrix Medical (Eden Prairie, MN; $600K SBIR), whose long-term goal is to grow human organs using a patient’s own cells, has spun off a portion of its business to create a new startup. ... transferred to Reprise Biomedical, the new business, two existing, FDA-cleared medical devices – Miromesh and Miroderm. Miromesh reinforces soft tissue and is used during plastic and reconstructive surgery, while Miroderm is used for managing wounds. [Maddy Kennedy, MinneInno, Jul 1, 19]

Discouraging military and diplomtic service. Trump administration said that children born to U.S. military members and government employees working overseas will no longer automatically be considered United States citizens. [Morgan Chalfant, The Hill, Aug 28, 19]

Zero meets 12000. “No, I don’t think this president has lied,” she [campaign spokesperson Kayleigh McEnany] told Cuomo, before repeatedly backing the honesty of Trump, who has given more than 12,000 false or misleading statements during his presidency, according to The Washington Post’s Fact Checker. [Timothy Bella, WashPo, Aug 28, 19]

Plus Therapeutics up 42% [Aug 27, 19]

Arcadia Biosciences down 23% [Aug 27, 19]

Arcadia Biosciences up 52% [Aug 26, 19] announced a binding term sheet agreement with Arista Cereal Technologies and Bay State Milling Company for commercialization of its high fiber resistant starch wheat in key wheat markets, including North America, Europe and parts of Asia. [company press release, Aug 26, 19]

Plus Therapeutics up 27% [Aug 26, 19]

Salarius Pharma (Houston, TX; no SBIR) up 21% [Aug 26, 19] The Ivy Brain Tumor Center at the Barrow Neurological Institute and Salarius Pharmaceuticals announced a collaborative partnership to test Salarius' therapeutic candidate, Seclidemstat, for the treatment of glioblastoma. The organizations will launch what they believe is the most comprehensive pre-clinical study to date, evaluating the effect of targeting LSD1 (lysine-specific histone demethylase 1A), a key enzyme that has increased expression in tumors of brain cancer patients. [joint press release, Aug 26, 19]

UES {Dayton, OH; tons of SBIR) won a potential eight-year, $90.3M contract to develop a technology for the U.S. Air Force identify molecular signatures of airmen performance. The company will conduct basic, applied and advanced research on molecular assessment sensing tools and demonstrate signatures in operational environments, the Department of Defense said. [Matthew Nelson, GovConWire, Aug 26, 19]

Taking the Long View. The Fed’s rationale for ignoring Mr. Trump’s pressure campaign is grounded in cold equations. Years of academic research and history show that nations that allow politics to guide interest rates risk more rapid inflation and are prone to painful boom-and-bust cycles. Most of the economics profession sees a monetary policy system free of political influence as an essential precondition for stable growth. [Jeanna Smialek, New York Times, Aug 25, 19]

Progenics Pharma up 17% [Aug 22, 19]

Retrophin (San Diego, CA; no SBIR) down 22% [Aug 22, 19] announced that the Phase 3 FORT Study evaluating the safety and efficacy of fosmetpantotenate compared to placebo in patients with pantothenate kinase-associated neurodegeneration (PKAN) did not meet its primary endpoint and did not demonstrate a difference between treatment groups. The study also did not meet its secondary endpoint. [company press release, Aug 22, 19]

Finch Therapeutics (Somerville, MA; no SBIR, founded 2004), a clinical-stage microbiome therapeutics company, announced the completion of a $53 million Series C financing [to] advance its pipeline of novel microbial therapies, including CP101, a Full-Spectrum Microbiota® (FSM®) therapy delivered in an oral capsule that is designed to contain a diverse community of microbiota and restore a balanced microbiome. [company press release, Aug 22, 19] total funding $95M [crunchbase.com]

Aperiomics (Sterling, VA; SBIR) announced the close of its Series A funding round of $1.8M, taking long strides toward detecting under-diagnosed infections. The startup’s testing kits use genomic sequencing and machine learning to identify pathogens that generally are difficult to diagnose. Doctors send a sample to Aperiomics, which extracts genetic information, identifies the bacteria or virus within the sample and sends back a report. [Kieran McQuilkin, DCInno, Aug 22, 19]

Thumb on the scale. The daily news briefing, which is sent to the [Department of Justice]'s 400-some immigration judges, included a link to a website that has been a known platform for white supremacists. [Reis Thebault, WashPo, Aug 22, 19]

Arcadia Biosiences up 24% [Aug 21, 19]

Harpoon Thera up 20% [Aug 21, 19]

Cree down 16% [Aug 21, 19] as Its Outlook for the Quarter Surprises Wall Street [Barron's, Aug 21, 19]

Rooster Bio (Frederick, MD; $200K SBIR, founded 2012) raises $22M [Baltimore Busiess Journal, Aug 21, 19] prior funding $22M [crunchbase.com]

Oncorus (Cambridge, MA; no SBIR, founded 2015), an oncolytic virus company focused to transform outcomes for cancer patients, announced the completion of an oversubscribed $79.5 million Series B financing. [company press release, Aug 21, 19] prior funding $60M [crunchbase.com]

Enjoy the ride. The federal government will rack up $12.2 trillion in deficits through 2029, according to a new projection from the non-partisan Congressional Budget Office (CBO), an $809 billion increase from its last projection in May. CBO, Congress’s official budgeting scorekeeper, said that the deficits would average 4.7 percent of GDP through the next decade, a significant increase from the 2.9 percent average over the past 50 years. [Niv Elis, The Hill, Aug 21, 19] Economically it means the federal government will spend that much more every year with borrowed money. And since the world is awash in investable cash, there will be little crowding out of private investment by a high cost of private debt. It's a partly Trumpian wonder world if you close your eyes to any eventual demand for debt repayment. It has worked for Trump for decades.

Synlogic (Cambridge MA; no SBIR) down 28% [Aug 20, 19] Synthetic biology startup has stopped development of SYNB1020 after the drug failed to lower blood ammonia levels in a phase 1b/2a trial. The engineered stain of [E-coli] performed no better than placebo in the small trial [Fierce Biotch, Aug 20, 19]

Plus Therapeutics (Cambridge MA; no SBIR) down 22% [Aug 20, 19]

Sarepta Thera (Cambridge MA; no SBIR) down 15% [Aug 20, 19]

Applied Research Associates (Albuquerque, NM; $25M SBIR) won a potential 10-year, $240M contract to provide operational support tools to aid the Defense Threat Reduction Agency in countering risks from weapons of mass destruction. The cost-plus-fixed-fee, indefinite-delivery/indefinite-quantity contract will include research, development, decision support analysis and technical reachback operational support, the [DOD]said. Work will take place at multiple agency-run facilities within Fort Belvoir in Virginia. [Nichols Martin, GovConWire, Aug 20, 19] If SBIR's advocates wanted SBIR to protect local jobs, do they now applaud a company's big contract in Virginia? Will a lot of smart New Mexicans abandon the state for Virginia?

Amyris Biotech (Emeryville, CA; $900K SBIR) up 20% [Aug 19, 19]

Oncternal Thera up 18% [Aug 19, 19]

Plus Therapeutics down 18% [Aug 16, 19]

Siamab Therapeutics (Newton, MA; no SBIR, founded 2006) developing novel glycan-targeted cancer therapeutics, has entered into a strategic agreement valued at up to $202 million with an undisclosed, large commercial-stage biopharmaceutical company under which such company will develop and commercialize antibody-based products targeting a tumor-associated carbohydrate antigen (TACA) identified by Siamab’s proprietary TACA discovery platform. [company press release, Aug 19, 19] prior funding $6.6M [crunchbase.com]

The FDA rejected the new drug application for golodirsen, the follow-up to Exondys 51, Sarepta’s first treatment for Duchenne muscular dystrophy (DMD), the company said in a statement. [Amirah Al Idrus, Fierce Biotech, Aug 19, 19]

Monopar Therapeutics (Wilmette, IL; no SBIR) filed to raise $40 million IPO. [to] start a phase 3 trial of a prophylactic treatment for a side effect of chemoradiotherapy. [Nick Paul Taylor, Fierce Biotech, Aug 16, 19]

Confident but worried. Trump said he is considering measures to bolster the economy [which he lauds in great helth], including a possible [standard trickle-down] reduction in capital-gains taxes, and continued to press the Fed to [huge] cut rates even as he played down warning signs of a possible slowdown. [ Rebecca Ballhaus, Andrew Restuccia, and Richard Rubin, Wall Street Journal, Aug 20, 19]

Solid Biosciences up 43% [Aug 16, 19] reported quarterly financial results

Alpine Immune Sciences up 24% [Aug 16, 19] reported quarterly financial results

Novavax up 18% [Aug 16, 19]

Arcadia Biosciences down 18% [Aug 16, 19] reported quarterly financial results

Jump ahead to next phase. As a result of their August 9, 2019 review, the DSMB recommended that the study be stopped and that all future patients be randomized to receive either REGN-EB3 [from Regeneron] or mAb114 [from Ridgeback BioTherapeutics (Miami. FL, no SBIR, founded 2015)] in what is being considered an extension phase of the study. This recommendation was based on the fact that an early stopping criterion in the protocol had been met. The preliminary results in 499 study participants indicated that those individuals receiving REGN-EB3 or mAb114 had a greater chance of survival compared to those participants in the other two arms. [Ridgeback press release, Aug 12, 19]

IonQ (College Park, MD; no SBIR, funded 2016) is a developer of quantum computing for commercial applications. .. total funding #20M [crunchbase.com] recently reported that its prototype computer, using 11 qubits made of ionized atoms, performed more complex calculations with greater accuracy than any rival machine. [Jeanne Whalen, WashPo, Aug 18, 19]

In designing the plane’s flight controls, the aerospace giant assumed that pilots should be able to sift through a jumble of contradictory warnings and take the proper action 100% of the time within four seconds. That’s about the amount of time that it took you to read this sentence. [Andrew Tangel, Andy Pasztor, and Mark Maremont, Wall Street Journal, Aug 16, 19]

Arcadia Bio up 15% [Aug 15, 19]

Polymath. the first metrologist to use a wave-length of light as a unit of measure, the inventor of the quincuncial projection of the sphere, the first known conceiver of the design and theory of an electric switching-circuit computer. ... fundamental discoveries in science and mathematics: the shape of the Milky Way galaxy; the first precise measurement of the Earth’s gravity and circumference; one of the most accurate and versatile projections of the 3D globe of the Earth onto 2D space; the chemistry of relations and working out the consequences of the discovery of the electron for the periodic table; the axiomisation of the law of the excluded middle, or Peirce’s Law: ((P→Q)→P)→P); existential graphs and the transformation of mathematics into an (quasi-)empirical component of studies on cognition; one of the first studies of the stellar spectra, particularly the spectral properties of argon; the invention of the then most accurate gravimetric pendulum; the first standardisation of the length of the metre by anchoring it to the length of a wavelength of light the most original and the most versatile intellect that the Americas have so far produced - Charles S Peirce (1839-1914),- says the leading Peirce scholar ever, Max Fisch. ... [Daniel Everett, Aeon, Aug 14, 19]

Novovax up 40% [Aug 14, 19] on a market bloodbath day

Solid Biosciences up 24% [Aug 14, 19]

Arcadia Bio up 16% [Aug 13, 19]

Myriad Genetics down 43% [Aug 13, 19] revenue in the fourth quarter was two percent below expectations largely due to lower reimbursement for our expanded carrier screening test,” said [CEO] Capone. [company press release, Aug 13, 19]

Renovacor (Philadelphia, PA; no SBIR), a preclinical-stage biopharmaceutical [Temple University spinoff] company focused on developing transformative gene therapy-based treatments for cardiovascular disease, today announced the successful completion of an $11 million Series A financing [to] advance the Company’s first-of-its-kind gene replacement therapy through filing of an IND in preparation to initiate human clinical trials in DCM patients who have mutations in their BAG3 gene. [company press release, Aug 14, 19]

Landos Biopharma (Blacksburg, VA; no SBIR), focused on the discovery and development of first-in-class oral therapeutics for patients with autoimmune diseases, announced the successful completion of its $60 million Series B financing round [company press release, Aug 13, 19] the first biotech to come out of Xontogeny, the accelerator started by former Sarepta Therapeutics chief Chris Garabedian [Fierce Biotech, Aug 14, 19]

Deciphera Pharma up 80% [Aug 13, 19] Announces Second Quarter 2019 Financial Results "In recent months, we've made substantial progress across our pipeline of novel candidates from our two Phase 3 GIST trials with ripretinib to the addition of DCC-3116, a potential first-in-class autophagy inhibitor aimed at treating mutant RAS cancers," said [CEO]Hoerter. [company press release, Aug 13, 19]

G1 Thera up 19% [Aug 13, 19]

Arcadia Biosciences up 54% [Aug 12, 19]

AMAG Pharma up 14% [Aug 12, 19]

Progenics Pharma down 16% [Aug 12, 19]

Paragon Space Development (Tucson, AZ; $15M SBIR) wins $5M in government contracts Company currently is working on 23 contracts [ Hayley Ringle, Phoenix Businesss Journal, Aug 6, 19] to develop COSMIC is a full flow phase separation device that separates liquid condensate from air with low power draw and low pressure drop in the flow path while supplying the separated condensate at pressure to the Water Processing Assembly (WPA) onboard the International Space Station (ISS). [company press release, Jul 10, 19]

Pay later .. or never. The U.S. budget gap widened further in July as federal spending outpaced revenue collection, bringing the deficit to $867 billion so far this fiscal year, a 27% increase from the same period a year earlier. [Kate Davidson, Wall Street Journal, Aug 12, 19] The wondrous USG credit card with no bank to force re-payment. With neither the Congress nor the POTUS willing to tell their supporters NO.

Arcadia Biosciences up 124% [Aug 9, 19] Verdeca, a joint venture between Arcadia Biosciences and Bioceres Crop Solutions, announced it has successfully completed the regulatory review process and received approval from USDA for its HB4(R) drought tolerant soybeans, which will allow for commercialization in the U.S. market. [company press release, Aug 8, 19]

Ally Therapeutics (Cambridge, MA; no SBIR) gene therapy company raised $10M according to an SEC filing. [Rowan Walrath, BostInno, Aug 9, 19] .... is developing a new technology that enables AAV to evade the innate immune response. [massbio.org]

Castle Biosciences (Friendswood, TX; no SBIR) announced thaat its [IPO] raised $73M. .... a commercial-stage dermatological cancer company focused on providing physicians and their patients with personalized, clinically actionable genomic information to make more accurate treatment decisions. [company press release, Aug 9, 19]

Marrone Bio Innovations (Davis, CA; $500K SBIR) announced that it has entered into a definitive purchase agreement to acquire Pro Farm Technologies OY [Finland], which will increase Marrone Bio’s market share and global platform in the $4.6 billion seed- and soil-treatment market. ... for $32M cash and shares [company press release, Aug 8, 19]

ORIC Pharmaceuticals (South San Francisco, CA; no SBIR), clinical-stage oncology company focused on developing cancer treatments that address mechanisms of therapeutic resistance, announced the closing of a $55 million Series D financing. [which] brings the total capital raised to over $175 million. [company press release, August 8, 19]

Corindus Vascular Robotics (Waltham, MA; no SBIR, founded 2001) up 77% [Aug 8, 19] a leading developer of precision vascular robotics, announced that it has entered into a definitive merger agreement to be acquired by Siemens Healthineers AG [Germany]. [for] approximately $1.1 billion [cash]. [company press relesase, Aug 8,19] prior funding $118M [crunchbase.com]

G1 Therapeutics up 27% [Aug 8, 19]FDA has granted Breakthrough Therapy Designation based on myelopreservation data in small cell lung cancer, an important step toward making trilaciclib available

Calyxt up 21% [Aug 8, 19] Reports 2(nd) Quarter Financial Results

Luna Innovations up 21% [Aug 8, 19]

Cerecor up 21% [Aug 8, 19]

RoosterBio (Frederick, MD; $200K SBIR, founded 2012), disrupting the market by radically simplifying human mesenchymal stem/stromal cell (hMSC) biomanufacturing, announced it has raised in excess of $15 million in an initial Series B financing [to] to expand the biotech startup's team and bolster R&D for its cell and gene therapy solutions. [company press release, Aug 6, 19] prior funding $6M [crunchbase.com]

Nucleus Biologics (San Diego, CA; no SBIR), a leader in precision cell culture, announces the acquisition of Primorigen Biosciences (Madison, WI; $5.4M SBIR, founded 2005). The addition of Primorigen’s Vitronectin XFTM and platform recombinant protein production technology will play a huge role in Nucleus’ strategy of offering traceable, reproducible and xeno-free (XF) cell culture ecosystems for the cell and gene therapy space. [Nucleus press release, Aug 5, 19] [prior funding $2.5M [crunchbase.com]

Blue Water Vaccines (Cincinnati, OH; SBIR), a developer of a universal flu vaccine, raised a $7 million seed round [Cincy Inno, Aug 8, 19]

VIDA Diagnostics (Coralville, IA; $2.4M SBIR, founded 2004) raised an undisclosed amount. total funding $10M [crunchbase.com]

Bayer AG and BlueRock Therapeutics (Cambridge, MA; no SBIR) announced an agreement under which Bayer will fully acquire BlueRock Therapeutics, focused on developing engineered cell therapies in the fields of neurology, cardiology and immunology, using a proprietary induced pluripotent stem cell (iPSC) platform [for] approximately USD 1 billion. [joint compaies press release, Aug 8, 19]

Oroboros Bio (Cambridge, MA; no SBIR) raised $5M in a $10M funding round, according to an SEC filing. [BostInno, Aug 8, 19]

Organovo Holdings (San Diego, CA; $1.6M SBIR) ) announced that it has engaged Roth Capital Partners (“Roth”) as its financial advisor to assist in the exploration of strategic alternatives [after] concluding that the Company had not generated decisive scientific data supporting the prolonged functionality and therapeutic benefit of its lead therapeutic liver tissue candidate, and that the necessary redevelopment of the tissue would require significant time, additional resources and development risks, and would likely not provide sufficient return on investment for the Company’s stockholders. [company press release, Aug 7, 19]

Rhythm Pharmaceuticals (Boston, MA; no SBIR), focused on the development and commercialization of therapeutics for the treatment of rare genetic disorders of obesity, today announced positive topline results from two pivotal, Phase 3 clinical trials evaluating setmelanotide, the company’s melanocortin-4 receptor (MC4R) agonist, for the treatment of pro-opiomelanocortin (POMC) and leptin receptor (LEPR) deficiency obesities. [company press relase, Aug 7, 19]

in the latest survey 87% of [economist] respondents were good to go with “trade war.” [Josh Zumbrun, Wall Steet Journal, Aug 8 19]

Early-stage medical device company, Cardio Flow (St. Paul, MN; no SBIR) received $4.3 million in equity funding from an undisclosed angel investor in early June. [siliconprairienews.com , Aug 8, 19]

Morphic Hodings up 24% [Aug 7, 19]

Athenex down 20% [Aug 7, 19] announced Positive Phase III Results on Oral Paclitaxel plus Encequidar and Increased Product Sales Guidance [company press release, Aug 7, 19]

Xencor down 20% [Aug 7, 19]

Cree and ON Semiconductor announced the execution of a multi-year agreement where Cree will produce and supply its Wolfspeed® silicon carbide wafers to ON Semiconductor, a global semiconductor leader serving customers across the spectrum of electronics applications. The agreement, valued at more than $85 million, provides for the supply of Cree’s advanced 150mm silicon carbide (SiC) bare and epitaxial wafers to ON Semiconductor for use in high-growth markets, such as electric vehicle and industrial applications. [company press release, Aug 6, 19]

Benson Hill Biosystems (St Louis, MO; $700K SBIR, founded 2012), a crop improvement company unlocking the natural diversity of plants, has entered into a partnership with Brownseed Genetics, (Bay City, WI; no SBIR) seed breeder of new corn hybrids that are higher in both oil content and essential amino acids. [Benson press release, Jul 29, 19] Benson total funding $132M including $32M announced Aug 2, 2019 [crunchbase.com]

SSTI and NSF are collaborating to bring important sessions for attendees at this year's conference on how to help your entrepreneurs access SBIR/STTR and how to support commercialization in your region. [SSTI, Aug 7, 19] See conference Agenda. Note that the only listed government SBIR speaker is from NSF, which while it has an interesting SBIR, cannot speak for the mission agencies with over half the SBIR money and a completely different help-ourselves approach.

This, too, shall pass. Trump, who has developed a pattern of endorsing and then abandoning proposed federal responses in the wake of mass shootings, knows the realities of the public debate: Congress has not passed major gun control legislation in two decades. [The Hill, Aug 7, 19]

GlycoMimetics (Rockville, MD; no SBIR) dowwn 69% [Aug 5, 19] [It] and its partner Pfizer disclosed that a 345-patient Phase 3 study, RESET, failed its primary and secondary goals. Rivipansel didn’t get sickle cell patients out of the hospital faster than a placebo, and it didn’t reduce the amount of opioids needed to deal with the pain. [Ben Fidler, xconomy.com, Aug 5, 19]

Prellis Biologics (San Francisco, CA; no SBIR, founded 2016) assembled $8.7 million in new funding alongside positive news from the first transplantation of its vascular tissue scaffolds. is building human tissues for drug development, and ultimately, developing human organs for transplantation. [Conor Hale, Fierce Biotech, Jul 31, 19] prior funding $10M [crunchbase.com]

Few perfect voters. Voters who are highly informed, ideologically consistent and politically active make up a minority of the electorate. [Nate Cohn, NYTimes, Aug 5, 19] The rest are unpredictable.

Discovering the Constitution. the “committee approval” requirements “are unconstitutional and are without legal effect,” say the USDA legal eagles to justify Ag's moving its research stuff to Kansas City for questionable reasons. The POTUS [temporary] chief of staff admitted it was for the purpose of shedding employees without seeking Congressional approval. The few Ag SBIR companes can expect turmoil and uncertainty as half the affected employees said "no go."

BioCardia down 64% [Aug 2,19] Announces Pricing of $10.0 Million Public Offering and Uplisting to Nasdaq [company press release, Aug 2, 19]

Acorda Thera down 49% [Aug 2,19] reported quarterly financials [company press release, Aug 1, 19]

Fluidign down 34% [Aug 2,19] announced financial results for the second quarter [company press release, Aug 1, 19]

A decade after its founding, biotech RegenxBio (Rockville, MD; no SBIR, founded 2009) made three big moves in the last week to get products to market. It struck a deal with Pfizer, giving the pharma giant licensing rights to its tech platform for developing a gene therapy treatment. Then it partnered up with Swiss biopharma Neurimmune AG to develop gene therapies for neurodegenerative diseases. And to top it off, RegenxBio launched a research program surrounding treatments for hereditary angioedema, a life-threatening blood disorder. That's one hell of a week. Read more from the WBJ [subscriber content]. [Kieran McQuilkin, DCInno, Aug 2, 19] total funding $112M [crunchbase.com]

Great tech ugly.The next generation of wireless internet [5G] will provide super-fast service, longer battery lives and a wealth of capabilities. ... providers across the country are facing resistance in installing the equipment, which can be attached to [perched on streetlights, traffic lights and buildings]. Many neighborhood groups consider the additions ugly. [Samm Quinn, Indianapolis Business Journal, Aug 2, 19] Just as ugly as wind turbines around the windy Indiana flatlands. Do they also object to tall towers carrying electricity to their homes and businesses?

Myriad Genetics (SALT LAKE CITY, UT; one SBIR in Y2K) up 54% [Aug 1,19] after the company published a filing with the [SEC] disclosing that UnitedHealthcare will begin covering the GeneSight Psychotropic test on the first day of October. The $2,000 genetic test is used to guide the treatment of individuals with major depressive disorder or anxiety disorders, by providing insight into which drugs they're most likely to respond to. [Yahoo Finance, Aug 1, 19]

Acadia Pharma up 17% [Aug 1,19] reported that its revenue in the second quarter increased 46% year over year to $83.2 million, fueled by continued momentum for antipsychotic drug Nuplazid. This easily topped the consensus Wall Street estimate of a little over $72 million in revenue. [Yahoo Finance, Aug 1, 19]

Abiomed (Danvers, MA; $17M SBIR) down 26% [Aug 1,19] after the company reported mixed quarterly results and lowered full-year guidance.[Yahoo Finance, Aug 1, 19]

Neocis (Miami, FL, one SBIR) raised $30M [Emon Reiser, South Florida Business Journal, Jul 16, 2019] transforming dental implant surgery with advanced robotics [company website]

Pumping the economy. Federal contract spending in fiscal 2018 increased for the third straight year to $559 billion, a 9% increase over 2017 spending and the highest level since 2010, when agencies spent $562 billion. [Courtney Buble, govexec.com, Aug 1, 19] the pump comes from not collecting enough taxes to pay for the stuff. Just like your credit card. Are you at least getting your share of the spending?

Always about me. “If they don’t want to trade with us anymore, that would be fine with me,” Mr. Trump said. [Wall Street Journal, Aug 1, 19] as he announced more tariffs against China. “Both sides now seem to be settling in for a broad and unremitting trade war that will last at least through this term of Trump’s presidency.” said Eswar Prasad, the former head of the International Monetary Fund’s China division. [New York Times, Aug 1, 19] from fantasyland: "China, they have to pay it," Trump told reporters. "They're paying for these tariffs. We're not. …Until such time as there is a deal, we'll be taxing them." [The Hill, Aug 2, 19] Sure, somebody pays taxes into the US Treasury, but it's almost always paid directly by the importer (usually a domestic firm), and never by the exporting country.. [taxpolicycenter.org]

the uncertainty created by Trump’s policy by whim — nobody knows what he’ll hit next — has surely deterred investment. Why build a manufacturing plant when, for all you know, next week a tweet will destroy your market, your supply chain, or both? [Paul Krugman, NYTimes, Aug 1, 19]

Exact Sciences moved to acquire Genomic Health, and plans to bring their cancer diagnostics up through a single commercial organization. For $2.8B. [Conor Hale, Fierce Biotech, Jul 29, 19]

Backward step. The president said a new deal with Beijing may not come until after the 2020 election, a significant departure from his earlier attempts to exert pressure on China. [Taylor Telford, Damian Paletta, David J. Lynch, Washington Post, Jul 30, 19] Meanwhile, Trump lashed out at China and the Fed, unsettling investors worried about mounting risks to the global outlook. [James Politi and Colby Smith, Financial Times, Jul 30, 19] China is not just another real estate financier to be horn-swoggled by big talk.

The simple math that should keep Republicans up at night: The most common age of Hispanics in America is 11. For whites? 58. [Philip Bump, Washington Post, Jul 30, 19]

ArunA Bio (Athens, GA; no SBIR) a leader in the development of neural exosomes for the treatment of neurodegenerative diseases, announced the completion of a $13 million common stock financing [that] will use the funding to support the development of its neural exosome delivery platform and neural exosome therapies for treating neurodegenerative diseases such as ALS, Huntington’s Disease and stroke. [CEO] Mark Sirgo said the new funding brings ArunA Bio’s total raised to nearly $24M. [company press release, Jul 24, 19]

Solid Biosciences up 34% [Jul 26,19] announced that it has entered into a securities purchase agreement with a select group of institutional investors and accredited investors for a $60 million private placement. [company press release, Jul 26, 19],

Achillion Pharma up 18% [Jul 26,19]

Neuralstem down 36% [Jul 26,19] announced the pricing of its underwritten public offering [to raise] $7,500,000 [company press release, Jul 25, 19]

Castle Biosciences (Friendswood, TX; no SBIR, founded 2007) announced pricing of its [IPO] expected to be $64.0 million. [company press release, Jul 24, 19]

Evelo Biosciences (Cambridge, MA; no SBIR, founded 2015) developing oral biologics that act on cells in the small intestine with systemic therapeutic effects, entered into a loan and security agreement for up to $45M with K2 HealthVentures, a health care investment firm. [company press release, Jul 25, 19] prior funding $132M [crunchbase.com]

Gemphire Therapeutics (Livonia, MI; no SBIR), a clinical-stage biopharmaceutical focused on developing therapies for the treatment of dyslipidemia as well as nonalcoholic fatty liver disease, and NeuroBo Pharmaceuticals (Boston, MA; no SBIR) clinical-stage biotech focused on novel, disease-modifying therapies for neurodegenerative diseases, jointly announced that they have entered into a definitive agreement whereby NeuroBo will [reverse] merge with a wholly-owned subsidiary of Gemphire in an all-stock transaction. [joint press release, Jul 24, 19]

Populism politics. Short-term tax breaks and giveaways from public funds for client groups whose votes you hope to win, combined with a determination to scapegoat and squeeze minorities and the ‘undeserving’ poor, is the very essence of populism. So is the assumption that patriotic-cultural gestures and spectacles like the launching of aircraft carriers will serve as compensation for mean lives. [James Meek, London Review of Books, Jul 26, 19]

Yes men more comfy. Mr. Ratcliffe, a third-term Republican from Texas and a former prosecutor, has embraced Mr. Trump’s theories about the Russia investigation and was among the sharpest questioners of Robert S. Mueller III, the former special counsel, at last week’s hearings. [Maggie Haberman, Julian E. Barnes and Peter Baker, New York Times, Jul 28, 19] Qualification for nation's chief intelligence officer? Won't interfere with the emperor's partisan policy making [increasingly surrounded by loyalists].

Aeglea BioTherapeutics (Austin, TX; no SBIR, founded 2013) up 20% [Jul 25, 19] announced that [FDA] granted Breakthrough Therapy Designation (BTD) to the Company's lead investigational therapy, pegzilarginase, for the treatment of Arginase 1 Deficiency (ARG1-D), a rare progressive disease presenting in early childhood that results in severe complications and early mortality. [company press release, Jul 25, 19] total funding $56M [crunchbase.com]

Neuralstem down 26% [Jul 25,19]

Trade wars easy to .... iRobot The maker of the popular Roomba line of robot vacuums launched its latest iteration called the s9 in late May with a starting price tag of $999. Unfortunately, that is also when tariffs on goods imported from China kicked in. iRobot thus had to raise the price of its already-pricey new vac by $100 to compensate, along with similar increases across several of its other models. [Dan Gallagher, Wall Street Journal, Jul 25, 19] ... easy to lower American profits

iRobot down 17% [Jul 24,19] reported lower earnings

TScan Therapeutics (Cambridge, MA; no SBIR) dedicated to unleashing the power of the immune system through life-changing T cell therapies, announced its Series B financing, with over $48 million raised since the company’s inception. [company press release, Jul 23, 29] TScan’s research is still in the lab, but the company is mapping a course that could lead to human testing in two years. [Frank Vinluan, xconomy.com, Jul 24, 19]

Hoth Thera up 59% [Jul 23,19] focused on unique targeted therapeutics for patients suffering from indications such as atopic dermatitis (eczema) and dermatological and chronic wound disorders, announced initial results of its Pilot Study of the BioLexa Platform's application on diabetic skin ulcers. ... the majority of the (test) wounds, treated with either BioLexa or the carrier base control of BioLexa, were fully closed and re-epithelialized. [company press release, Jul 22, 19]

Achillion Pharma up 29% [Jul 23,19]

Marinus Pharma down 70% [Jul 23,19] results showed that, in the study, ganaxolone administered as a six-hour infusion followed by oral administration was generally safe, well-tolerated and provided clinically meaningful reductions in Hamilton Rating Scale for Depression (HAM-D17) scores at early time points of 6 hours and 24 hours after start of treatment. [company press release, Jul 23, 19]

Acadia Pharmaceuticals’ treatment for Parkinson’s disease-related psychosis failed a Phase 3 trial that was studying use of the drug for schizophrenia patients who haven’t fully responded to existing therapies. [Sarah de Crescenzo, xconomy.ccom, Jul 22, 19]

Frequency Therapeutics (Woburn, MA; no SBIR) a clinical-stage biotech company, closed a $62M Series C funding round. brings the company's total equity financing to $147M. [Rowan Walrath, BostInno, Jul 23, 19]

Don't answer? EPA filed changes to its FOIA rules to the Federal Register, which became effective immediately. The changes affirmatively grant that political appointees, including the administrator and deputy administrators, can respond to FOIA requests, either releasing or withholding documents. [Erich Wagner, govexec.com, Jul 22, 19] Oh, no, says the Congress. The FOIA law specifies only a few reasons [proprietary, investigatory, classified, legal advice] for not releasing the requested document(s). And political embarrassment is not one of them.

Xenetic Biosciences down 31% [Jul 22,19] announced it closed its previously announced $15.0 million underwritten public offering [company press release, Jul 22, 19]

Neuralstem down 18% [Jul 22,19]

3D Glass Solutions (Albuquerque, NM; no SBIR, founded 2006), a leading innovator of glass-based, three-dimensional (3D) passive RF devices, announced it has closed $12 million in series B equity funding, bringing the company’s total equity funding to more than $19 million. [company press release, Jul 9, 19]

Joyn Bio (Boston, MA and Woodland, CA; SBIR), an agtech company entered a partnership with NewLeaf Symbiotics (St. Louis, MO; no SBIR, founded 2012) valued at up to $75M to bring innovation and sustainability to modern agriculture with a new class of microbes that benefit crop health and protection. Joyn will gain access to NewLeaf's library of proprietary, strains of plant colonizing microbes and will engineer those microbes to bring novel disease and pest control options to farmers. [Rowan Walrath, BostInno, Jul 22, 19]

America First — and by ourselves — is now the policy. .. The GOP was once the party of economic expansion through access to world markets. Trump and his team have turned this approach on its head. .. This new party is one that merely responds to the president’s whims, as expressed in tweets of limited depth and base vocabulary. His ideas can and do change without notice or discernible ideological reason. [Judd Gregg, The Hill, Jul 22, 19]

They got their wish. Cotton farmers in Arkansas are hoping for a swift resolution to the trade spat with China. [Wall Street Journal, Jul 22, 19] They enthused for Trump who promised "trade wars are good"'. Now they have both with neither doing well.

Neuralstem (Rockville, MD; $1.9M SBIR) down 31% [Jul 19,19] two days after 1-20 reverse split

Marker Therapeutics (Houston, TX; no SBIR) down 27% [Jul 19, 19] response to preliminary data from a Phase 1/2 clinical trial evaluating its MultiTAA T cell therapy in patients with pancreatic adenocarcinoma, the most common type of pancreatic cancer. Investors appear to have been expecting a more significant treatment effect. [seekingalpha.com, Jul 19. 19]

Finch Therapeutics (Somerville, MA; no SBIR) biotech working on microbiome therapies, raised $53.5M in a funding round, according to an SEC filing. [Rowan Walrath, BostInno, Jul 19, 19] prior funding $41M [crunchbase.com]

Startup Carlsmed (San Diego, CA; no SBIR) and startup spine imaging system company Precisive Surgical (Seattle, WA; no SBIR) have completed a merger to develop a personalized surgical workflow platform [which] will combine clinical intelligence, advanced image recognition, and 3D printing to enable earlier surgical intervention delivering personalized implants to patients with complex, multi-level spinal alignment deviation, according to Carlsmed. [Nancy Crotti,medicaldesignandoutsourcing.com, Jul 19, 19]

Be careful what you wish for. For years, Chinese investment into the United States had been accelerating, with money pouring into autos, tech, energy and agriculture and fueling new jobs. But growing distrust between the two countries has sent Chinese investment plummeting by nearly 90 percent since President Trump took office. [Alan Rappeport, NYTimes, Jul 21, 19]

Outlook darkening. Domestic profits, and the worldwide profits of American firms, peaked relative to GDP in 2012, and have plateaued since then. President Donald Trump’s tax cuts boosted earnings in 2018. But the underlying trend is one of stagnation. [The Economist, Jul 18, 19] Trump and his Republican captives want to run on the strong economy and their trickle-down economic fantasy plus the pull of white nationalsm championed by a serial liar carney-barker.

Leuko (Boston, MA; no SBIR), an MIT-born technology startup developing the first non-invasive white blood cell monitoring device, today announced it has raised $1.8 million in seed financing [company press release, Jul 17, 19]

Pyxis Oncology (Boston, MA; no SBIR), a newly formed immuno-oncology company, launched with a focus on developing a new family of antibody-based immunotherapies derived from novel insights into the biology of the tumor microenvironment. Leaps by Bayer led the Company's USD 22 million Series A financing [joint company press release, Jul 17, 19]

Fulcrum Therapeutics (Cambridge, MA; no SBIR), a clinical-stage biopharmaceutical focused on improving the lives of patients with genetically defined diseases in areas of high unmet medical need, with an initial focus on rare diseases, announced the pricing of its [IPO] with gross proceeds of $72.0 million [company press release, Jul 17, 19]

Longeviti (Cockeysville, MD; no SBIR) raising up to $12.6M , is developing and commercializing implants for use in complex brain surgeries. [Morgan Eichenseh, Baltimore Business Journal, Jul 18, 2019]

The scent of politics and revenge. Trump Says He May Intervene in Huge Pentagon Contract Sought by Amazon. ... For the president to weigh in on the award of a major government contract would be highly unusual, raising questions of improper political influence. [Scott Shane and Karen Weise, New York Times, Jul 19, 19] What relevant and proper contribution could a president make in a contract selection competition within the announced criteria? If he did so, the contract would be tied up for years in the courts, and the DOD would fall even further behind in adapting to the cloud.

scPharmaceuticals (Burlington, MA; no SBIR, founded 2014),up 32% [Jul 17, 19] focused on developing and commercializing products that have the potential to optimize the delivery of infused therapies, advance patient care, and reduce healthcare costs, announced [that] FDA confirmed that it does not believe it will be necessary to conduct additional clinical safety, efficacy, or pharmacology studies as part of scPharmaceuticals' NDA for FUROSCIX. [company press release, Jul 16, 19] total funding $61M [crunchbase.com]

AVROBIO up 20% [Jul 17, 19] announced the pricing of an underwritten public offering [to raise] approximately $120million. [company press release, Jul 16, 19]

Seattle Genetics up 19% [Jul 17, 19]

Xenetic Biosciences down 49% [Jul 17, 19] announced the pricing of an underwritten public offering [to raise] approximately $15 million. [company press release, Jul 17, 19]

The scientists, leaders and investors of Dune Medical Devices (Atlanta, GA; no SBIR, founded 2002 ) [are] working towards eradicating the need for more than one operation to remove cancer from the body—a feat more than 20 companies have been unable to accomplish in the past two decades. The startup, which was founded in Israel in 2004 and later moved its operations to Atlanta, was founded by Dan Hashimshony, who discovered how to differentiate healthy tissue from cancerous tissue using physics and an algorithm. Using the algorithm, Hashimshony developed a pen-like probe that could determine if tissue was cancerous during surgery. [Madison Hogan, AtlInno, Jul 17, 19] total funding $50M [crunchbase.com]

Torque Therapeutics (Cambridge, MA; no SBIR) biotech startup developing immunotherapies for cancers, raised $38.3M in a funding round, according to an SEC filing. [Sri Kalyanaraman, BostInno, Jul 17, 19] earlier announced that [FDA] granted Fast Track designation for Torque’s first Deep-Primed™ T cell immunotherapy program, TRQ-1501 (Deep IL-15 Primed T cells) [company press release, Jun 19, 19]

Black Diamond Therapeutics (Cambridge, MA; no SBIR, founded 2016 in New York) biotech startup developing precision medicines for cancers, raised $44.2M in an $87.2M funding round, according to an SEC filing. [Rowan Walrath, BostInno, Jul 17, 19] prior funding $112M [crunchbase.com]

BioPath Holdings up 33% [Jul 16, 19]

Beta Bionics (Boston, MA; $400K SBIR, founded 2015), a startup using machine learning and artificial intelligence to develop the world’s first autonomous bionic pancreas, closed its Series B and B2 rounds of funding, bringing the company’s total capital to $126M. [Sri Kalyanaraman, BostInno, Jul 16, 19]

Trefoil Therapeutics (San Diego, CA; no SBIR, one $500K NIH grant) announced it raised $28 million in an oversubscribed Series A financing. ... is developing novel engineered fibroblast growth factor-1 proteins (eFGF-1) as a regenerative pharmacologic therapy to treat serious corneal endothelial diseases and epithelial disorders. [company press release, Jun 16, 19] prior funding $5M [crunchbase.com]

Orchestra BioMed (New Hope, PA; no SBIR), a biomedical innovation company providing high-impact solutions for large unmet needs in procedure-based medicine, announced it has completed a $34 million Series B-1 Preferred Stock financing ... Orchestra BioMed’s June 2019 partnership with Terumo included a $30 million up-front payment as well as significant future milestone payments from Terumo and meaningful revenue sharing through sales royalties and exclusive drug formulation supply payments. [company press release, July 10, 19] prior funding $100M [crunchbase.com]

Net loss tariffs. According to data from U.S. Customs and Border Protection, the tariffs President Trump has imposed on Chinese imports have generated $20.8 billion so far, Ana Swanson and Jim Tankersley of The New York Times reported Tuesday. ... But Swanson and Tankersley point out that the president has committed about $28 billion to payments for American farmers hurt by his trade war, leaving a net loss on that basis alone. [Michael Rainey, Financia Times, Jul 16, 19] But have faith, Trump says, "Trade wars are good, and easy to win." and most recently Trump said that there’s still a long way to go to reach a deal with China, threatening to slap tariffs on another $325 billion of Chinese goods. [Yun Li, CNBC, Jul 16, 19]

In the Archives older stories back to 1996

news and views about government programs, politics, attitudes ...1996-1997; 1998; 1999; Y2K; 2001 , 2002-2003 ; 2004-5; 2006; 2007-08 2009-2010; 2011-2012; 2013-14 ; 2015; 2016; 2017-18

BMDO/ MDA including SBIR the doings of star wars

Miscellaneous Stories 1996-1997; 1998-1999; 2000-2001; 2002-2003 ; 2004-5 ; 2006; 2007 2009-2010 ; 2011-2012; 2013-2014; 2015; 2016; 2017

IPO and Venture Markets 1996-1998 .... 1999-2005 ... 2006-present

Quotes steal them if you like

Note: in these old stories, many links are dead, obsolete, or missing

Stories about companies; 1-Al .. Am-Az .. B .. C ... D-E .. F .. G-H .. I-J .. K-L .. M ... N-O ... P ... Q-R .. S1-Se .. ... Sf-Sz .. T-U .... V-Z

Companies in the Archives

10X Genomics ..... 1366 Technologies ... 1st Detect ... 21-Century Silicon ... 21st Century Systems .... 23andMe ... 24M Technologies ... 30 Second Software ... 360fly ..... 3Bar Biologics .... 3C Semiconductor ... 3DEO .... 3D Glass Solutions ..... 3Dnamics ..... 3D Robotics .... 3D Systems ..... 3D Technology Laboratories .... 3F ... 3iNanotech .... 3PrimiR ... 3Scan ..... 3-V Biosciences .... 3VR ... 410 Medical Innovation .... 454 Life Sciences .... 4C Medical Technologies .... 4D Molecular Therapeutics ..... 4s3 Bioscience ... 5D Robotics ..... 7AC Technologies ... 89Bio ... 908Devices ... 9Mile Labs

A10 Networks ... A123Systems ... A4 Pharma .... A&G Pharmaceutical ... Aastrom Bioscience .. Abacus Technology ... ... Abaxis .... Abcombi Sciences ..... Abeona Therapeutics ..... AbGenomicsInternational ... Abiomed ... Ablative Solutions .... Ablexis ...... ABL Technologies .... Abpro Therapeutics ..... AbSci .... Absorbent Materials ... Abundant Robotics ..... AbVitro ... Acadia Pharma ... Acambis .. Accel Diagnostics ..... Acceleron Pharma ... Accelrys ... Accentia BioPharmaceuticals ... Accent Therapeutics ..... Accera .... Access Pharmaceuticals ... Access Scientific .... Accion Systems ..... Accumetrics ... AccuraGen ..... Accurate Automation .. Accuray ... Accuri Cytometers ... Acelerox .... Acelity .... AcelRx Pharmaceuticals ... Acera Surgical .... Acer Thrapeutics .... Acetylon Pharmaceuticals ... Achaogen ... Achates Power ..... Achillion Pharmaceuticals ... ACIST Medical Systems .... Acorda Therapeutics ... Acorn Cardiovascular ... Acquia .... AcroMetrix ... AcryMed ... ActaCell ... Actasys .... ACT Biotech ... Active Power ... ActivBiotics ... ActivMedia Robotics .... Acton Pharmaceuticals ... Actuality... Actuate Therapeutics .... Acucela ... AcuFocus .... Aculight ... Acumentrics ... AcuraStem .... Acutus Medical .... Adamas Pharmaceuticals ...... Adamis Pharmaceuticals ... Adapteva .... Adaptimmune Therapeutics .... Adaptive Biotechnologies ..... Adaptive Computing ... Adaptive Phage Therapeutics ..... Adaptive TCR ... Adarza BioSystems ..... Addiction Therapeutix ... Addrenex Pharmaceuticals ... Adelor ... Adenosine Therapeutics ... Adesto Technologies .... Adeza Technologies ... Adherex Technologies ... Adhesys Medical .... Adial Pharmaceuticals .... Adicet Bio .... AdiMab ... ADispell ... Adlyfe .... ADMA Biologics .... Admittance Technologies .... Admune Therapeutics ..... Adnexus Therapeutics ... Adrenergics .... Advanced BioHealing ... ADS Biotechnology ... Aduro BioTech .... Advanced Animal Diagnostics .... Advanced Biologics ..... Advanced Bionics ... Advanced Cell Diagnostics ... Advanced Cell Technology (now sub to Bio-Techne) ... Advanced Ceramics .... Advanced Circulatory ..... Advanced Countermeasures Systems ... Advanced Diamond Technologies .... Advanced Electron Beams ... Advanced Fuel Research ...Advanced Life Sciences ... Advanced Lighting Technologies ... Advanced Liquid Logic ... Advanced Magnetics ... Advanced Photonix .... Advanced Programming Concepts ... Advanced Receiver Technologies .... Advanced Scientific Concepts ..... Advanced Targeting Systems .... Advanced Technology Materials.(ATMI) ... Advanced Uro-Solutions ..... AdvanDx ... Advantic ..... Advaxis ..... Adventrx ... Adverum Biotechnologies ..... Advion BioSciences ... Adynxx ...... Aegea Medical ... Aegerion Pharmaceuticals .... Aeglea BioTherapeutics Holdings ..... Aerial BioPharma .... Aerie Pharmaceuticals ... Aerin Medical ..... AerisPhotonics ...... Aerius Photonics ... Aerodyne Research ... Aero Farms System ... Aerovel ..... AeroVironment ... Aerpio Therapeutics .... AesRX ... AETC ... Aethlon Medical ... Aethon .... Aevi Genomic Medicine ..... Affectiva .... Afferent Pharmaceuticals ..... Affigen .... Affinimark Technologies ... Affinity BioReagents ... Affinium Pharmaceuticals ..... Affinivax .... Affomix .... Affymax ....Affymetrix ... aFraxis ... AgBiome ..... AgeneBio .... Agennix ... Agenovir ..... Agenus .... Agere Pharmaceuticals ..... Agile Materials ... Agile Planet ... AgileSwitch .... Agile Therapeutics .... Agility Robotics ..... Agilis Biotherapeutics .... Agiltron...Agilvax .... Agilyx .... Aagios Pharmaceuticals... AgraQuest .... Agritope... Agrivida ... Agro Biosciences .... Aguila Technologies.....Ahura Scientific.... Aiko Biotechnology ... Aileron Therapeutics .... Aimmune Therapeutics (formerly Allergen Research) ..... airtricity... Airware .... Airxpanders .... Airway Therapeutics .... ait laboratories... Akadeum Life Sciences .... Akamai Physics Akarna Therapeutics ..... Akashi Therapeutics ..... Akcea Therapeutics ..... Akebia .... Akero Therapeutics ... Akermin ..... Akers BioScience ..... Akita Innovations ... Akouos .... Akrevia Thera .... Akron Polymer Systems ..... Akron Surface Technologies ..... Akros Medical .... Alabama Cryogenics ... Alafair Biosciences .... Albany Molecular (AMRI) ...A? nanotech .... Alcon .... Alcresta .... Aldagen ... Aldatu Biosciences ..... Aldea Pharmaceuticals ... . Alder biopharma Aldevon ..... Aldeyra Therapeutics (formerly Aldexa Therapeutics) .... Alector .... Alexar Therapeutics ..... Alexion ... ....Alexza .... Alfalight.... Algaeventure Systems ... Algenetix .... Algeternal .... Algorithmia ..... Alien Technology .... Alimera sciences.... Alios BioPharma ....Aliva biopharmaceuticals ..... AliveGen .... Alivio Therapeutics ..... Alkermes... Alkeus Pharmaceuticals ... Allakos ... Allcast .... Allegro Diagnostics .... Allegro microsystems ... Allena Pharmaceuticals .... Allergy Amulet ..... Allerquest .... Alleviant Medical .... Allied BioScience ..... Allied Minds .... Alliqua .... Allos Alloy Polymers .... Alloy Surfaces ..... Allurion Technologies ... Allylix ... Alnara Pharmaceutical ... Alnylam... Alper Biotech ... Alphabet Energy .... AlphaCore Pharma ... Alphamed.... Alphatec Holdings ..... Alphavax ... Alpine Biosciences .... Alpine Data Labs .... Alpine Immune Sciences ..... Alseres .... Algeternal .... Alta Devices ... AltAir Fuels ... Altair Therapeutics ... Altamira Technologies .... AltaRock ... AltheaDX .... Althea Technologies ... Altimmune ..... Altor ... Altra ... Altura Medical ... Altus Pharmaceuticals ... ALung Technologies ... Alvine Pharmaceuticals .... >Alycone Lifesciences .... Alzeca ..... AMAG Pharmaceuticals ... Alzheon ..... Amaranth Medical .... Ambarella ..... Amberwave ... Ambiq Micro .... Ambit Biosciences .... AMBP Technology ... Ambri .... Ambrx ... Ambry .... Ambys Medicines .... Amendia .... American Bionics ..... American Gene Technologies International .... American Lithium Energy .... American Medical Systems .... American Science and Engineering ... America Stem Cell, now Targagyme .... American Superconductor ... American XTAL .. Ames Technology ... Amgen ... Amicus Therapeutics .... Amionx ..... Amnis ... AMO Pharma ..... Ampio Pharmaceuticals ..... Ampla Pharmaceuticals ... Amplimmune .... Amplyx Pharmaceuticals ..... Amprius .... ARMO BioSciences .... Amylin Pharmaceuticals ... Amylyx ..... Amyris Biotechnologies ... Anacor Pharmaceuticals ... Anadys Pharmaceuticals ... Anakim Biologics .... Analog Computing Solutions .... Analytical Space ..... AnaptysBio ... Anavex Life Sciences .... Anchor Therapeutics ... Ancora Pharmaceuticals ... AnDAPT ..... Anexon .... Anew Optics ... Angeion ... AngioDynamics ... Angiologix ... Angstrom Medica .... Angstron Materials ... Animalgesic Labs .... ANI Pharmaceuticals ... Animetrics .... Anivax .... Anivive Therapeutics ..... Annexon Bioscience ..... ANP Technologies ..... Ansoft ... Ansun Biopharma (formerly NexBio) .... Antegrin Therapeutics ..... Anthera Pharmaceuticals .... Anthos Therapeutics ..... Antigenics ... Anue Systems ... Anulex Technologies ... Anybots ... AOBiome Therapeutics (formerly Nitrocell) .... AOptix Technologies ... Aortica ..... APA Optics (Enterprises) ... Apellis Pharmaceuticals ..... Apexigen ... Aperion Biologics .... Aphios ... Apic Bio .... Apieron ... Apnex Medical ... ApniCure ..... ApoCell .... ApoGen Biotechnologies .... Apollo Diamond ... Apollo Endosurgery ... Apollomics (previously CBT Pharmaceuticals) .... Apoplogic Pharmaceuticals ... Applied Biomolecular Technologies .... Applied Biosystems .... Applied Defense Solutions ..... Applied Genetic Technology ... Applied Nanotech .... Applied NanoWorks ... Applied Optimization ..... Applied Optoelectronics ... Applied Physical Electronics ... Applied Physical Sciences ... Applied Precision ..... Applied Proteomics ..... Applied Quantum Technologies .... Applied Quantum Technology .... Applied Research Associates ... Applied Science and Technology ... Applied Signal Technology ... Applied Therapeutics ...... AppThwack .... Aprecia Pharmaceuticals .... Apricus Biosciences ... APS BioGroup .... Apse .... Aptalis Pharma .... Aptevo Therapeutics ..... Aptima ... AptamiR Therapeutics .... Aptinyx .... Aptose Biosciences .... Aptus Endosystems ... Aquaback Technologies ... Aqua Bounty ... Aquacue .... AquaHarmonics ..... Aqua Metals .... AquaMost ... Aquarius Technologies ... Aquestive Therapeutics .... AqueSys ... Aqueti .... Aquion .... Aradigm .... AragonPharmaceuticals ... Aratana Therapeutics ..... Arbor Biosciences< ..... Arbor Biotechnologie ..... Arbor Pharmaceuticals ... Arbovax ... Arbutus BioPharma (formerly OnCore) ..... Arca Biopharma .... Arcadia Biosciences ..... Arcadia Pharma ..... Arcantatura... Archemix ... ArcherDX ......Arch Innotek ..... Arch Oncology ..... Arch Therapeutics ... Arctic Sand Technologies .... Arcturus Therapeutics .... Arcus Biosciences ..... Ardea Biosciences ... Ardelyx .... Ardian .... Arena Pharmaceuticals ... Argentum ..... Arginetix ... Argo AI ..... ArgonST ... Argos Therapeutics ... Aria CV ... Ariad Pharmaceuticals .. Ariosa Diagnostics ..... Arista MD .... Arista Networks .... ARIZ Precision Medicine .... Arkis BioSciences ....... Arkansas Power Electronics ..... Armadillo Aerospace ... Armetheon .... ARMO BioSciences .... Armonica Technologies .... Armorworks ... Armune BioScience ..... Aro Biotherapeutics .... Aronora ..... Arpeggi .... ArQule ... Arrakis Therapeutics ..... Array ... Array Information Technology ..... Arresto Biosciences .... Arrien Pharmaceuticals ... Arrivo BioVentures ..... Arrowhead Pharmaceuticals ..... Arrowhead Research .... Arsanis ... Arsenal Medical .... Arstasis ... Artel .... Arteriocyte ... Arterys ..... ArthroCare ... Arthrosurface ... Artisan Pharma ... Artizan .... Artrility Medical ..... Arvegenix ..... Arvinas .... Arxan Technologies .... Aryx Therapeutics ..... Aryx ... Arzeda ... Asana Medical (now Regentsys) .... Asante Solutions ..... Ascelegen Therapeutics .... Ascension Orthopedics ... Ascent Solar Technologies .... Ascent Therapeutics .... AsclepiX Therapeutics .... Aseptia .... Ash Access Technology .... AstroWatt .... Aspen Aerogels .... AspenBio Pharma .... Aspen Products Group .... Aspen Technology ... Aspyrian Therapeutics .... Assurex Health ..... Astex Therapeutics ... Asthmapolis .... Astralux ... Astrobotic Technology .... Astronautics Corp. of America ... AstroPower... AstroTerra .. Astrum Solar ... Astute Medical .... Astute Medicales ... Asuragen ... Atacama ..... Atara Biotherapeutics ..... Ataxion .... Athenex (formerly Kinex) ..... Athenix ... Athens Research ..... AtheroGenics ... AtheroMed .... Athersys .... ATI Industrial Automation ... Atlantia ... Atmocean ..... Atmospheric Glow Technologies ... Atomate ... Atomic Medical Innovations ..... Atomometrics ... Atomwise ..... Atoptix .... Atossa Genetics ... Atreaon .... Atreca .... Atreon Orthopedics ..... AtriCure ... Atrium Medical ... ATRP Solutions ... aTyr Pharma ..... Audentes Therapeutics ..... Audience ... Augmenix .... AUM Cardiovascular ... Aura Biosciences .... Auris Health .... Auris Medical .... Auris Surgical Robotics ..... Aurora Algae ... Aurora Flight Sciences .... Aurora Imaging Technology ... Aurora Spectral Technologies ... Auspex Pharmaceuticals ... Ausra ... Auterra .... AuthenTec .... Autolus Therapeutics .... Automated Dynamics ... Automated Medical Instruments .... Autonet ... Aushon Biosystems ... AutoGenomics .... Autonomic Materials .... Autonomic Technologies ..... Autonomous Technologies .... Auxilium Pharmaceuticals ... Avalanche Biotechnologies .... Avanir Pharmaceuticals ... Avant Immunotherapeutics ... Avanti Metal ... Avaxia Biologics ... Avedro ... Avelas Biosciences .... Aveo Pharmaceuticals ... Avery Therapeutics ..... AveXis .... Aviation Resources Delaware .... AVI BioPharma ... Avici Systems ... AvidBiotics .....Avidity Biosciences .... Avid Radiopharmaceuticals ... Avila Therapeutics ... Avinger .... ... Aviragen Therapeutics (formerly Biota Pharmaceuticals) ..... Aviron ..... Avisa Pharma .... Avita Medical Americas ..... Avitude .... Avrobio ..... AVT Simulation .... Aware ... Axcella Health (was Pronutria) ..... Axelo .... Axerion Therapeutics ... Axial Biotech .... Axial Biotherapeutics ..... Axion BioSystems ..... Axion Power ... Axis Clinicals .... Axis Semiconductor ... Axium Nanofibers ...... Axium Pharmaceuticals .... Axogen .... Axonia Medical ....Axonics Modulation Technologies Axsome Therapeutics ..... Axsun Technologies ... Ayasdi ..... Azaya Therapeutics ... Azelon Pharmaceutical ... Azimuth .... Aziyo Biologics ..... Azure Biotech ..... AzurRx BioPharma

Baby Genes .... Bacterial Robotics .... BacterioScan .... Baebies ..... Bagaveev .... Ballard Power ... Bamboo Therapeutics ..... Bandgap ... Banner Life Sciences ..... Banyan Biomarkers ... Bardy Diagnostics .... BarioSurg ..... Baryonyx .... Barrier Therapeutics ... Baseload Renewables .... Basis Science .... Bastion Technologies .... Batu Biologics ..... Bauhaus Software ..... Baxano ... Baxano Surgical .... BayoTech ..... Beacon Biomedical ..... Beacon Power ... Beam Therapeutics ..... Beat Biotherapeutics .... Beeco ... Behavioral Recognition Systems .... Bellicum Pharmaceuticals .... Belmont Instrument .... Benchmark Automation ... BeneChill ... Benefuel ... BeneVir Biopharm .... Bennett Aerospace .... Benson Hill Biosystems ..... Benvenue Medical .... Berg .... BerrieHill Research ... BESS Technologies .... BetaBatt ... BetaLED .... LEDBG Medicine ... Bettergy .... Bexion Pharmaceuticals .... Bina Technologies .... Bind Bioscience ... Bind Therapeutics .... BinOptics ..... BiO2 Medical ... BiO2 Technologies ... BioAmber ... BioAdvanTek ... BioAffinity Technologies ..... Bioanalytical Systems ... BioBehavioral Diagnostics ... BioBridge Global ..... BioCardia ..... BioCentra Molecular Innovations ..... Biocept ... BioChemics ..... BioClin Therapeutics .... Bicycle Therapeutics ..... Bien-Etre Labs ..... BioCold Genesys .... Bioconnect Systems .... BioConsortia ..... BioCritica ... BioCryst Pharmaceuticals ... BioDelivery Sciences ... Biodesix .... BioDirection ..... BioDtech ... BioFactura ... ..... BioE ... BioFire .... BioFluidica ..... Biogenic Reagents .... BioGreenChoice ... BioHaven Pharmaceuticals ..... Bioheart ... Biohelix ... Bio-Imaging Technologies ... Bioincept .... BioKier ..... Biolex Therapeutics ... BioLife4D ..... BioLink Life Sciences ... Biolinq (formerly Electrozyme) ,,,, Biologics ... BioMagnetic Solutions .... BioMarin Pharmaceutical ... BioMarck Pharmaceuticals .... bioMASON ..... Biomatrica ... BioMedical Enterprises ... Biomedical Sciences ..... Biomedical Structures ... BioMedix .... Biomeme .... Biometric Signature ... BioMimetic Therapeutics ... BioMotiv .... BioNano Genomics ... BioNanomatrix ... Bionostics Holdings ... Bio-Path Holdings ..... Biophan Technologies ... Biophysical ... BioProcessors ... Bioptigen ... Bioptix .... BiOptix Diagnostics ..... BioPulping International ... Biopure ... Biorasis ..... BioRelix ... BioResource International ... BioRestorative Therapies (formerly Stem Cell Assurance) .... BioSante Pharmaceuticals ... BioScale .... BioSense Technologies ... BioSensics .... BioSentinel Pharmaceuticals ... BioSig Technologies ..... Biosortia Pharmaceuticals .... BioSphere Medical .... Biostage (formerly Harvard Apparatus Regenerative Technology) ..... BioStructures .... Biosurfaces .... Biosym Technologies later Accelrys .... BioSystem ... Biota Pharmaceuticals .... Bio-Techne ..... BioTechnique .... BioTechPlex ..... Biotectix .... Biotel .... BioTelemetry (formerly CardioNet) ..... BioTex .... Biothera ... BioTheranostics ... Bio Time ... Biotix ... Biotronic NeuroNetwork ..... Biotronik .... BioTrove ... BioVaxys .... Bioventus ..... Biovest International .... BioVex ... BioVirtua ..... Bird Rock Bio (formerly RuiYi) ..... Birich Technologies .... Biscayne Neurotherapeutics ..... Bitstream ... Black Diamond Therapeutics .... Black-I Robotics ... Black Sand ... BlackThorn ..... BladeLogic ... Blasch Precision Ceramics .... Blaze Bioscience ... Blend Therapeutics .... BL Healthcare ... Block Engineering ... Bloom Energy ... Bloo Solar ..... BluDiagnostics ..... Blue Belt Technologies ... Bluebird bio ... BluDiagnostics .... Bluefin Robotics ... Bluegrass Proteins .... Bluegrass Vascular Technologies .... Blueprint Medicines ... BlueRock Therapeutics ..... Blue Sky Batteries ... Bluewater Bio International ... Blue Water Vaccines .... Bolder Surgical ... Bolt Biotherapeutics .... Bolt Threads .... Boom Supersonic ..... Boragen .... Boston Biochem ... Boston Biomedical ... Boston Dynamics ... Boston Engineering ... Boston Micromachines ... Boston Micromachines (formally Boston Electrometallurgical .... Boston-Power ... Boston Therapeutics ... Bot Dolly .... Boundless ... BoXZY ..... Braeburn Pharmaceuticals ..... BrainCells ... BrainScope .... Brain Sentry .... Brain Tunnelgenix Technologies .... BrainXell ..... Branch Medical Group ..... Brayton Energy .... Breathe Technologies ... Breethe .... Breonics ... BreviTest Technologies ..... Brewer Science ... Bridger Photonics .... Bridgelux ... Brightsource Energy ... Bright View ... Brimrose Corp of America ... Briteseed .... Brock Rogers Surgical ... Bromium .... Brooks Automation ... Bruker Daltonics .... Buffalo BioLabs ..... Burl Concepts ..... Burr Oak

C12 Energy ... C2Sense .... C3Nano ... C4 Therapeutics .... C8 Sciences .... C9 ... Cabaletta Bio .... CABG Medical .... Cadence Pharma .... CadheRx Therapeutics ..... Caisson Biotech .... Calabazas Creek Research .... Caladrius Bioscience ... Cala Health ..... Calando Pharmaceuticals ... Calbiotech .... Calera ... Caliber Biotherapeutics .... Calibra Medical ... Calient ... California Wave Power Technologies ..... Calimmune ..... Caliper Life Sciences .... CaliSolar ... Calistoga Pharmaceuticals ... Calithera BioSciences .... Calixa Therapeutics ... Callidus Biopharma ... Calporta Therapeutics .... Calspan .... Caltech Metals ... Calysta .... Calyxt ..... Cambridge Endoscopic Devices ... Cambridge Heart .... Cambridge Research & Instrumentation ... Cambrios Technologies .... CAMX ..... Candela Laser .... Cancer Genetics .... Cancer Prevention Pharmaceuticals .... CanDiag .... Canopy Biosciences ..... Capesym ... Capillary Biomedical ..... Capio Biosciences .... Capnia ... CAPP Medical ..... Capricor Therapeutics .... Cara Therapeutics .... Carbon ..... Carbon Design Systems ... Carbtex Technology .... Carbylan Therapeutics ..... Cardeas Pharma .... CardiacAssist ..... Cardiac Concepts ... Cardiac Dimensions ... Cardiac Science ..... Cardialen ..... CardiAQ Valve Technologies ... Cardica ... CardioDx ... CardioFocus ... CardioInsight Technologies ..... Cardiokinetix ..... CardioMag ... CardioMEMS .... Cardionomic .... CardioNXT ..... Cardiorobotics ... Cardiosolutions ... Cardiosolv .... CardioSpectra ... CardioTech ... Cardiovate ..... CardiOx ... Cardioxyl Pharmaceuticals .... CareDx (formerly XDx) .... Caribou Biosciences ..... Carigent Therapeutics .... Carisma Thera (formerly CARMA Therapeutics) ..... Carmot Therapeutics ..... Carnegie Robotics .... Carnegie Speech ... .... Carnot BioSciences .... CaroGen .... Carter Aviation Technologies .... Carticept Medical ... Cartiva ..... Cascade Designs ... Cascade Microtech ... Cascadian Therapeutics (formerly Oncothyreon) ..... Casma Therapeutics .... Castle Pharmaceuticals .... Castle Creek Pharmaceuticals Catabasis Pharmaceuticals ... Catadon Systems ... Catalyst Biosciences ... Catalyst Pharma .... Catalytic Innovations ..... Catalyze ..... Catelectric .... Cebix .... Cedarburg Pharmaceuticals .... Cedilla Therapeutics ..... CeeTox ... Celadon ... Celator Pharmaceuticals ... CelcuityCeldara Medical ..... Celladon .... Cellara .... Cell Care Therapeutics ..... Cellceutix .... CellCyte Genetics ... Cell Design Labs ..... Celldex Therapeutics ... ..... Cellectar ... Cellerant Therapeutics ... Celleration .... Cell Genesys ... CellRight Technologies ..... Cellular Bioengineering ... ... Cellular Bioengineering ..... Cellular Biomedicine Group ..... Cellular Dynamics International .... Cell>Point .... CellSavers ..... Cellscape .... Cellscript ..... Cell Signaling Technology ...Cell Therapeutics (now CTI BioPharma) ... CellTraffix ... CeloNova Biosciences ..... Cel-Sci .... Celsion ... Celtaxsys ..... Celula..... Celularity ..... CellzDirect ... Cempra Pharmaceuticals. .... CeNeRx BioPharma ... Centocor .... Centrexion Therapeutics ..... Centrose ... Centice .. Century Therapeutics .... Centritec Seals ... Cephalon ... Cepheid ... Cephalon ... Ception Therapeutics ... Cequent Pharmaceuticals ... Cerebras Systems ..... Ceradyne ... Ceramitron ... Cerapedics .... Ceramatec ... Cerevast Therapeutics .... Cerealus Holdings ... Cerecor .... Ceregene ... Cerahelix .. Ceres Nanosciences ..... Cerexa .... Cerion Enterprises ... Cermet ... Cernostics ..... Cerulean Pharma ... Cerus ... Cervel Neurotech .... Cesca Therapeutics .... Ceterix Orthopaedics ... CFD Research .. CFX Battery .... CGI Pharmaceuticals ... ChaCha ... Chantilly BioPharma .... Chapman Innovations ... Charles River Analytics .... Charles River Lab ... Charter Medical ..... Chase Therapeutics .... CHASM .... Chatham Therapeutics ..... Checkerspot ..... Chemat ... Chembio Diagnostic Systems .... ChemImage ... Chemir Analytical Services ... ChemoCentryx ... Chemtura .... Chesapeake Sciences ...Chesson Labs ... Chiasma .... Chimera Bioengineering ..... Chimerix ... Chlorogen ... Choice Therapeutics ... Chondrogenics ... Chordia Therapeutics .... Chorum Technologies .... ChromaCode ..... ChromaDex ..... Chronix Biomedical ... Chrysalis BioTherapeutics .... Cibus Global ... Cidara Therapeutics .... Ciena ....Ciencia ... Cilion .... CimaBay Thera ..... CinCor Pharma .... CinRx .... Ciranova ... Circle Technologies ..... Cirius Therapeutics ..... CivaTech Oncology .... CiVi Biopharma ..... Civitas Therapeutics ..... Claret Medical .... Clarassance ..... Claresta Solutions .... Clark-MXR ...Claros Diagnostics .... Clean Diesel Technologies ... Clear Catheter Systems .... ClearCount Medical Solutions .... ClearEdge Power .... Clear Guide Medical .... Clearside Biomedical ... Cleave Biosciences ... Cleveland BioLabs ... Cleveland Polymer Technologies ..... CleverSet ... Clinical Data ... Cloudant ... CloudMade ... Cloud Pharmaceuticals (formerly Teradiscoveries) .... Clovis Oncology ... Clovis Tech ..... CMC Biologics .... C-Motive Technologies .... CoAdna,Holdings ..... CoAxia .... Cobalt Biofuels ... Cocrystal Discovery ... Codexis ... Codiak BioSciences ..... Codon Devices ... Co-D Therapeutics .... Cofactor Genomics .... Cogenra .... Cogentix Medical ..... Cognex ...Cognition Therapeutics .... Cognitive Code ... Cohera Medical .... Coherus Biosciences .... Cohesive Technologies ... ColdQuanta .... ColdWatt ... Collagenex Pharmaceuticals ... Collegium Pharmaceutical ... CoLucid Pharmaceuticals ... Columbia Labs ..... CombiMatrix ... CombinatoRx ..... Combined Energies .... Combinent BioMedical Systems ... Comet Therapeutics .... Comfort Motion Technologies ... Commonwealth Biotechnologies ... Commonwealth Fusion Systems ..... Compact Membrane Systems ...Compass Therapeutics .... Compellent Technologies ... Compendia Bioscience ..... Complete Genomics .... Complexa ..... Conatus Pharmaceuticals ... Concert Pharmaceuticals .... Concordia Fibers ...Concurrent Technologies ... Conductus .. Confluence Life Sciences ..... ConforMIS ... Cognigen .... Conispire .... ConjuGon .. Connecticut Valley Bindery ... Consonus Technologies ... Constellation Pharmaceuticals .... Context Therapeutics ..... Contour Energy Systems ControlRadSystems ..... Convelo Therapeutics .... Conventus Orthopaedics ..... Convergen ... ConverGene .... Convio .... Convoy Therapeutics .... Cool-Bio .... CoolCAD Electronics .... CoolChip Technologies .... Cool Earth Solar .... Cooligy ... CoolTech .... Corbus Pharmaceuticals ..... Corcept Therapeutics ... Cordex Systems .... CoreStreet ... CoreTek ... .Corgenix Medical ... Corindus ....Corinthian Ophthalmic ... Corium International .... Corixa .... CorMatrix Cardiovascular .... Cornami ..... Cornerstone Research ... Cornerstone BioPharma then Cornerstone Therapeutics ..... Cornerstone Therapeutics .... Coronado Biosciences ... CorQuest Medical ..... Correx ... Corridor Pharmaceuticals ... Cortana ..... Cortendo AB ..... Cortexyme .... Corvidia Therapeutics ..... Corvus Pharmaceuticals ..... CosmosID ..... CoStim Pharmaceuticals .... Cougar Biotechnology ... Coulbourn Instruments .... Coulter Pharmaceuticals ... Cour Pharmaceutical Development .... Coverity ..... Creare ... Creative Hybrid Solutions .... Creatv MicroTech .... Cree Research ... Crescendo Bioscience .... Crinetics Pharmaceuticals .... CrispTek .... Critical Therapeutics .... CritiTech ... Crossbar .... Cross Current ..... CrossFire ... Cruise Automation .... Crux Biomedical ... CryoCor ... CryoLife ... Cryomedical Sciences ..... Cryptonite ..... Crystal IS ... Crystal Systems ... Crystallume ... CSA Engineering ... CS-Keys ... CTD Holdings ..... CTI BioPharma (formerly Cell Therapeutics) .... Cubist Pharmaceuticals ... Cue Biopharma .... Cullinan Oncology ..... Cumberland Pharma .... CuraGen ... Current Motor ... Curtana Pharmaceuticals .... Custom Electronics .... CVD Equipment ..... CVRx ... CV Therapeutics ... Cyanotech ..... Cyberdyne .... CyberKey Solutions ... Cyberkinetics Neurotechnology ... Cybernet Systems ... CyberOptics ... Cydan .... Cykloburn Technologies ..... CymaBay Therapeutics .... Cymbet ... CyMedica Orthopedics ..... Cymer ... Cynosure ... Cyntellect ... Cypher Genomics ... CyPhy Works ... Cypress Bioscience ... Cyrus Biotechnology ..... Cyteir Therapeutics ..... Cyterix Pharmaceuticals ... CytImmune .... CytoBioScience ..... Cytocentrics ..... CytoCore (formerly Molecular Diagnostics) ..... Cytocybernetics ..... CytoDyn .... Cytogel Pharma .... Cytokinetics ... Cytometix ....CytomX ... Cytonome .... Cytori Therapeutics ... Cytophil CytoSolv ... Cytosorbents ..... Cytovas ... CytRx ..... Cytyc ... CyVek

Dabble ..... Dairyvative Technologies ..... Daktari Diagnostics ... Dance Biopharm .... Dara BioSciences ... Daré Bioscience Operations .... Dart Therapeutics ... DaStrong .... Datafiniti .... Data Physics ... DataRobot ..... Dato (formerly GraphLab) .... Datuit .... daydream.io ..... Daylight Solutions .... DayStar ... DayZero Diagnostics ..... DBS Energy ... DCL Medical Laboratories ... Deca-Medics ... deciBel Research .... Decibel Therapeutics ..... DecImmune Therapeutics ... Deciphera Pharmaceuticals ..... Decision Biomarkers ... Deepwater Wind .. Defense Engineering .... Defense Research Associates .... Defibtech ... Dekkun .... Delcath ... Delinia ..... Deltanoid Pharmaceuticals ... Denali Medical ... Denali Therapeutics ..... Dendreon ... DeNovo Sciences .... DeNovis ... Deposition Sciences .... DermAvance Pharmaceuticals ... DermBiont .... Dermira ... Desalitech .... Descartes Labs ..... Design Knowledge ..... DesignMedix ..... Detcon ..... DE Technologies ... Devicix ..... Dew & Ken Group ... Dewey Electronics ... Dewpoint Therapeutics .... Dexcom ... Dharmacon ..... Diagnostic Biochips .... Diagnostic Hybrids ... DiaMedica ..... Diamond Foundry ..... Dianomi Therapeutics .... Diatomix ..... Dicerna Pharmaceuticals ... Diffusion Pharma ..... DiFusion Technologies ... Digene ..... Digirad ... DigiSight Technologies ..... Digital Fusion ... Digital Lumens ... Digital Optics ... Dignify Therapeutics .... Dimien .... Dimension Therapeutics .... DioGenix .... Dipexium Pharmaceuticals ..... Directed Manufacturing .... Directed Perception .. Disarm Therapeutics .... Disc Dynamics ... Discovery Genomics ..... Discovery Labs .... Displaytech ... Distributed Energy Systems ... Divergence ... Diversified Energy ... D. Light ... DMC Biotechnologies ... DNAnexus ..... DNAPrint Genomics ... DNAtrix .... DNV GL .... Dova Pharma ..... DoX Systems ... Dracen Pharma ..... Dragon Systems .. Dragoon ITCN ..... Drilling Info ... DrillMap .... DropWise .... DR Technologies ..... DrugCendR .... DSM .... DT Solar ... DuBay Ingredients ... duPont Aerospace ... Dura Biotech .... Durata Therapeutics ... Durin Technologies .... DVS Sciences .... DxUpClose .... Dyadic International ..... Dyax ...DynaBil Industries ... Dynasil ... Dynavax Technologies ... Dyne Thrapeutics ... Dynetics .... Dynogen Pharmaceuticals

E3 Clean .... Eagle Optoelectronics ... Earl Energy .... EarLens .... Earth Networks .... Earthrise Nutritionals ... eASIC ..... Eboo Pharmaceuticals .... EBR Systems ..... Ebullient .... Echelon .... Echodyne ..... Echometrix ... EchoPixel ..... Echo Therapeutics (was Sontra)... ECI Biotech ... ECM Technologies ..... Ecocurrent ... EcoPesticides .... EcoPro Polymers ..... Eccrine Systems ..... Ecovative Design ... Edaptive Computing .... Eden Bioscience ... Edenspace Systems ... Edge Therapeutics ..... Edico Genome .... Edison Agrosciences ..... Editas Medicine .... EEStor ... Effector Therapeutics .... Egalet .... eGenesis .... Eiger BioPharmaceuticals ..... Eikos ... E-Ink ... EIS .... Ekos ... EKR Therapeutics .... Ekso ... Elcelyx Therapeutics ... Electrical Geodesics ..... ElectroCell Technologies ... ElectroChemical Systems ... Electro Energy ...Electromed ... Electro Optical Sciences ... Electro Scientific ... Electrozyme .... Elementary Robotics .... Elemetric Instruments ... ElevateBio .... Elevation Pharmaceuticals ... Eleven Biotherapeutics ... Elira Therapeutics ..... Elixir Biopharm ... Elixirgen Therapeutics ..... Elixir Pharmaceuticals ... Ellipse Technologies ..... Elon ... Elstar Therapeutics ..... eMagin .. Embera NeuroTherapeutics .... Embodied .... EmboMedics ..... Embrex .. EMCORE ... Emerald BioStructures .... Emergent BioSolutions ... Emergent Technologies ... EM Photonics .... Empire Genomics .... Empire Robotics .... EMRes Technologies ... Emtora Biosciences (formerly Rapamycin Holdings) .... Emulate .... Enable Injections ...... Enanta Pharmaceuticals ..... EnChroma ..... Encite ... Encoded Genomics .... Encoded Therapeutics .... Encompass Bioscience ..... Encore Vision .... Encysive Pharmaceuticals ... Endeavor Robotics ..... Endece ... Endgame Technologies ... EndoChoice .... Endocyte ... EndoGastric Solutions ... Endo International ..... Endoscopic Technologies ... Endosee ..... EndoStim .... Endotherapeutics ..... Ener1 ... EnerG2 ... Energen ... Energesis Pharmaceuticals .... Energetiq Technology ... Energid Technologies ... Energous ..... Ener-G-Rotors ... Energy Control ... Energy Conversion Devices . .. Energy Focus ..... Energy Recovery ... Energy Solutions ... Energy Storage Systems ..... EnerMat Technologies ..... EnerMed ..... Enertech Environmental ... EnerVault ... Engineered BioPharmaceuticals .... Engineered Propulsion ...Engineous Software ... Enlibrium ..... Enlight Bioscience ... EnSync Energy Systems (formerly ZBB Energy) ..... Ensysce Biosciences ... Entasis Therapeutics ..... Entech ... Entegrion ... Entellus Medical ..... Entera Biotech .... Entergem Ventures .... EnteroMedics ... Entia Biosciences ..... Entira Bio .... Entopica Therapeutics ... EntreMed ... Entrada Therapeutics ..... Entra Pharmaceuticals ... ENTrigue Surgical ... Envia Systems .. Entrotech Life Sciences ..... Entvantage Diagnostics ..... EnviroFlight ..... Envisia Therapeutics ..... Envistacom .... EnVivo Pharma ... Enzenia ... Enzium ... Enzo Biochem ... Enzymatics ... EnzyMed ..... Enzyvant ..... EO2 Concepts .... EOIR ... Eonix .... EpiBiome .... EpiBone .... Epicentre Biotechnologies .... Epic Sciences .... Epic Systems ..... Epicypher .... EpiEP ... Epion ... Epiphany Solar Water Systems .... Epitomics ... Epiva Biosciences ..... EpiVax ... EpiWorks .... Epix Pharmaceuticals ... Epizyme ... Eppin Pharma .... EqualLogic ... Equex ... Equillium .... Equipment Concepts ... EraGen Biosciences ... Erallo Technologies ... Erasca .... Ercole Biotech ... ERT ..... Escalier Biosciences BV ..... Escalon Medical .... E-Scape Bio ..... Escient Pharmaceuticals ..... Escoublac .... eScription ... eSolar ... Eso-Technologies ... Esperance Pharmaceuticals ..... Esperion Therapeutics ..... Essential Biotechnology ..... Essential Medical .... Essentient .... Essex... Eta Devices ..... Eta-Gen .... Etegent Technologies ... E-Tek Dynamics ... Eton Pharma ..... Euclid Labs .... Euclises Pharmaceuticals ..... Eureka Therapeutics ..... Euthymics Bioscience ... EVapt .... Evelo Therapeutics .... Evena Medical ..... Ever Cat Fuels ... Evergen Biotechnologies ... Evergreen Solar ... Everspin Technologies .... Evestra .... Evident Technologies ... Evofem Biosciences .... Evoke Pharma ..... Evolution Robotics ... Evolv .... Evolve BioSystems ....Evolved By Nature ..... EWI .... Exact Sciences .... Exagen Diagnostics ... Excelimmune ... Excel Technology .... Excision BioTherapeutics ..... Exelixis ..... Exelixis Plant Sciences ... Exemplar Genetics .... Exo ..... Exogenesis ..... Exone .... Exonics Therapeutics .... Exosome Diagnostics ..... Exovita .... Biosciences .... ExploraMed NC4 ... Expression Analysis .... Exquadrum .... Exsulin ....Extreme Molding ... Extremity Innovations ... EyeGate Pharmaceuticals ... EyeNetra .... EyeTel

Fallbrook Technologies ... Famigo ... Faraday Pharmaceuticals .... Farodox Energy Storage ... FarSounder ... Far-Tech.... FastCAP Systems ... Fate Therapeutics ... Fathom .... Fe3 Medical .... FEI ... Femasys .... Femta Pharmaceuticals .... Ferrate Treatment Technologies ... Ferric Contrast ...... FerroKin BioSciences .... Fervo Energy .... Feuz Manufacturing ... FGC Plasma Solutions ..... Fiber and Sensor .... Fiberight ... Fiber Materials ... Fibersense ... Fiberstar .... Bio-Ingredient Technologies ... Fibertek .... Fibrocell Science ... FibroGen ... Filter Sensing Technologies ... Finally Light Bulb ..... Finch Therapeutics Group ..... FineLine Prototyping .... Finisar ... Fire Alarm Specialty Design ..... Firefly BioWorks ... Firefly Energy .... Firefly LED ... First Solar ... Fisker Automotive ... Five Prime Therapeutics .... Flex Biomedical ... Flexion Therapeutics ... Flex Pharma .... Flextronics America .... Flexus Biosciences .... FLIR Systems .. FloDesign Wind Turbine ... FlowCardia ... FlowMedica .... FlowMetric .... Flow Metrix ... FluGen ... Fluidic Energy ... Fluidigm ... Fluid Innovation Group ... Fluidnet ... Fluidnet FluoroPharma ... Fog Pharma ..... Foghorn Therapeutics .... FokusLabs .... FoldRx Pharmaceuticals ... Follica ... Footnote .... Foresight Biotherapeutics .... Forest Devices .... Forge Therapeutics ..... F-Origin ... Forma Therapeutics ... Formlabs .... For-Robin ..... ForSight Vision5 .... Fortis Therapeutics ..... Forty Seven ..... Forum Pharmaceuticals ..... Forus Health ... Foster-Miller .... Foundation Medicine ... Fox Chase Chemical Diversity Center .... Fractal Antenna Systems ... Fractyl Labs ..... Freedom Meditech ... Free Flow Power ... Free Form Fibers .... Freenome ..... Froedtert Health ..... Frontier NanoSystems ..... Frontier Technology ..... Front Range Biosciences .... FTL Solar ... FuelCell Energy ... Fuel Tech .. Fulcrum Therapeutics ..... Fulgent Therapeutics ..... Full Spectrum Genetics .... Furiex .... Fused Innocation. ... Fusion Coolant Systems ... Future Technologies

G1 Therapeutics ..... G3 .... Gadusol Laboratories (aka Seaceuticals) ..... Galderma .... Galectin Thera ..... Galenea ... Galena Biopharma .... Galera Therapeutics ..... Galil Medical ..... Galleon Pharmaceuticals ... GAM Enterprises .... GameSalad ... Gamma Medica Ideas ... Garland Technology ..... Garwood Medical Devices ..... GATR Technologies ..... G-Con .... Gecko Biomedical .... Gecko Robotics .... Gel Combs .... Gelesis ... Geltech ... Gema Diagnostics .... GEMFIRE .. Gemin X Pharmaceuticals ... Gemmus Pharma ... Gemneo Bioscience ..... Gemphire Therapeutics ...... Gemstone Biotherapeutics ..... Gen9 ... Genaera ... Genalyte ... Genapsys .... GenAudio .... Gene by Gene .... GeneCentric Diagnostics ... Genelabs Technologies ... Gene Logic ... Geneoscopy ..... General Compression ... General Pneumatics ..... Generation Bio ..... Generex Biotechnology ... Gene Security Network .... GeneSegues Therapeutics ..... GenesisLabs .... GeneSystems ... Genetesis .... Genetic Networks ..... Genetix Pharmaceuticals ... GeneTx Biotherapeutics ..... Geneu .... Genia Technologies .... GenMark Diagnostics .... Genoa Pharmaceuticals ..... Genocea Biosciences ... Genomatica ... Genome Profiling ... GenomeQuest ... Genomic Health ... Genomind .... Genoptix Medical Laboratory ... Genor ... Genprex .... Gen-Probe ... GenSpera .... GenTel BioSciences ... Gentris ... GenturaDx ...nbsp; GenVec ... GenWay Biotech ..... Genzyme .... Geocent .... Geocove ..... Geomagic ... GeoMed Analytical ... GeoVax Labs ... Geospiza ... Germfalcon ..... Geron ... Gevo ..... GI Dynamics ... GigOptix ... Gilead Sciences .... Giner . .. Ginkgo BioWorks .... Glauconix ..... Glaukos .... GlideLine Systems ... Gliknik ... Global Blood Therapeutics ...... Global Cancer Diagnostics ..... Global Positions ... Global Blood Therapeutics .... GlobeImmune .... Gloucester Pharmaceuticals ... Glowforge ..... GlucaGo ... GlycoFi ... GlycoMimetics .... GlyGenix ... Glympse Bio .... Glyscend ..... GlySens ... GMZ Energy ... GnuBio .... Goddard Labs .... Goldfinch Bio ..... Good Start Genetics .... Gore Photonics ... Gossamer Bio ..... Gotham Biotech .... Gotham Therapeutics ..... GPC-Rx ... gRadiant Research ... Gradiant .... GraftWorx ..... Grail ..... Graphene Energy ... Graphenix Development .... Graphic Surgery ... GraphLab (now Dato) .... Grassroots Biotechnology ... Greatbatch ... GrayBug ..... Graybug Vision ..... Great Basin Scientific ..... GreatGrow Maryland ....Great North Lab .... GreatPoint Energy ... Green & Grow .... GreenFuel Technologies .... Greenlight Biosciences .... GreenMark Biomedical ..... Green Mountain Radio Research .... GreenSight Agronomics ..... Green Sulfcrete ..... GreenTech America ... Greenwich Geriatrics .... GridBridge .... Grid Therapeutics ..... Gritstone Oncology ..... GRO Biosciences ..... Group14 Technologies ..... Grove Instruments ... Grow Home Organics .... GSI Technology ... GT Advanced Technologies ... GTC Biotherapeutics ... G-Tech Medical .... GT Equipment .... GTI Diagnostics ... GT Medical Technologies ..... GTx .... Guardant Health .... Guided Surgery Solutions .... Guided Therapeutics .... .... Guided Therapy Systems ..... Gynesonics ..... G-Zero Therapeutics

2 Energy Now ...... H2O Score ..... H2Pump ... H2Sonics .... H3 Biomedicine ... HNC Software ... Halozyme ... Hana Biosciences .... Hansen Energy and Environmental .... Hansen Medical ... Haplogen Genomics ..... Harbor Technologies .. Hardcore Computer ... HarkerBio .... Harmony Enterprises .... Harpoon Medical .... Harpoon Therapeutics .... Harvard Apparatus Regenerative Technology .... Harrisvaccines .... Harvard Bioscience ... Harvest Automation .... Harvest Power ... Harvest Technologies .... Healionics .. Health Diagnostics Laboratories .... HealthMyne .... Healthtronics .... Hearforward ... Heartland Robotics .... HeartWare International ... Heat Biologics .... ... HeatGenie ... Helicos BioSciences ... Helion Energy .... Heliovolt ... Helius Medical Technologies ..... Helix Therapeutics ... Helomics (formerly Precision Therapeutics) ..... Hemadvance ..... HemaQuest Pharmaceuticals ... Hemarrest ... Hemera Biosciences .... Hemispherx Biopharma .... HemoGenyx .... Hemoshear Therapeutics ..... HemoSonics..... Hemostasis ... Hennepin Life Sciences .... Hepregen ... Heraeus Medical Components .... Herley Industries ... Hermes Biosciences ... HexaTech .... Hexfuel .... Hibernaid .... Highbury Defense Group .... High Impact Environmental .... High Performance Technologies ... High Point Pharmaceuticals ..... Histogen .... HighRes Biosolutions .... Histogenics ... HistoRx ... HistoSonics .... HJM Precision ..... HocusLocus ..... Hoku Scientific ... Holaira .... Hollingsworth & Vose .... Hollis-Eden Pharmaceuticals ... Holomni .... Homology Medicine ..... Honeycomb Batteries .... Hontek ... Hookipa Pharma .... Hoopers Island Oyster Aquaculture ... Hoppe Tool .... Hoth Therapeutics ..... Howe Industries .... Hsiri Therapeutics ..... HTG Molecular ..... HTSS ... Humacyte ... Humanetics ..... Human Genome Sciences ... Human Metabolome Technologies .... HuTerra .... Huya Bioscience International .... Hybritech ..... Hybrivet .... HYCOR Biomedical ... Hydra Biosciences ... HydroCision ... Hydrogen Safety ... HydroLogic Industries .... Hygeia Therapeutics ... HyperBranch Medical Technologies ... Hyperion Therapeutics ... HyperMed ... HYPRES .. Hy-SyEnce ... HyTrust

IAP ... IBC Advanced .... iBiquity Digital ..... Ibis .... Iblogix .... IBT Laboratories ... Icagen .... Icardiac.... Ichor Medical Systems .... Iconic Therapeutics ..... Icos.... ICX.... Idaho.... Ideal Converters ... Ideapaint.... Ideaya Biosciences ..... Idera Pharmaceuticals ..... ID Genomics .... Idevices ... IDx ..... iFirst Medical Technologies ...... IFM Therapeutics ..... Igenica Biotherapeutics .... IGM Biosciences ..... Ignyta.... Ii-IV .... Ikaria... Ikonisys... Illinois Superconductor.... Illumigen.... Illumina.... Illuminating Diagnostics ..... Illuminoss.... Illumitex.... Imagen Energy .... Imagevision.... Imaging Biometrics... Imagineoptix ... Imago Instruments... Imanis Life... Imbed Biosciences... Imetalx... Immco... Immersion... Immtech... Immucell .... Immucor .... Immune... ... Immune... Immune Pharma .... Immunetics... Immunex... Immunexcite... Immuneworks... Immunexpress ..... Immunic ..... Immunicon... ImmunoCellular Thera .... ImmunoChemistry Technologies ..... Immunocore... Immunogen... Immunome ..... Immunomedics..... Immunomic Therapeutics ..... Immunophotonics ... Immurx... .... Immusant... Immusoft ..... Impact Biomedicines .... Impact Proteomics .... Impact Science... Impel Neuropharma... Imperium Renewables... Impinj... Implant Sciences... Impossible Foods .... Imprimis Pharmaceuticals .... Imprint Energy .... Impulse Monitoring ... Imricor Medical Systems ..... Imris ..... Imthera... I-nalysis ... Inari Agriculture .... InCarda Therapeutics .... INCELL .... Incelldx ..... Incitor (now XF Technologies) .... Incodema3D ..... Incontrol Research... InCube Labs ..... Incyte ....Incytu... Indalo Therapeutics ..... Indiana Nanotech... Indi Molecular ... Industrial Heat ..... Industrial Perception... Inentec ... InfaCare Pharmaceutical .... Infarct Reduction Technologies .... Infinera... ... Infinia... Infinite Electronics .... Infinity... Infinium .... Inform Genomics... Infoscitex... Inframat... Infraredx... Infrascan... Inf Robotics ... Infusion Medical ... Ingeneus... Ingeneron ..... Inhibitex... Inhibkase Therapeutics .... Inhibrx< .... INI Power... Inland Labs ..... Inmobly .... InnAVasc Medical .... Inneroptic... Innerpulse... Innocrin Pharmaceuticals ..... Innography... ... Innopad... Innotec ..... Innovalight... Innovari Energy Design Microplate Scientific... pulmonary solutions.... silicon... Innovate Biopharmaceuticals ..... Innovative Spinal... Innovative... Innoventiontech ... Innovention (now Ccardiorobotics) ... Innovative Trauma or... Innovolt ... Innowave... ... ... Innoviva ... Innov-x... Inocucor ..... Inorganic Specialists... Inotek... Ino .... Inova Labs Biomedical... Inovio... Inovise Medical ..... Inozyme Pharmaceuticals ..... Inphase... ... Inphi... Inpria ..... Inscripta ..... Insert MRI... Insight... ..Insite Vision...... Insitu... InSitu Biologics ..... Insmed... Inspired Solar Systems ... Inspire... Insulet Labs ... Intact Vascular... Intaglio... Intalio ... Intarcia Therapeutics ... Integenx... Integra Group Diagnostics... Integral Molecular ..... Integrated BioTherapeutics .... Integrated Diagnostics .... Integrated Diagnostics InDi .... Integrated DNA Technologies ..... Integrated Fuel... ... Integration Associates... Intelect Medical Intelleflex ... Intellia Therapeutics ..... Intellicyt Automation Bio-systems ... Intelligent Devices .... Intelligent Epitaxy Technology ..... Intellimedix ..... Intelliphage.... Intellirad Control... .Intellisense .... Intelomed ....Inter-4... Interactive Supercomputing ... Interdigital Interlace .... Intermagnetics General ...Intermolecular ... Intermune.... International Stem Cell ... Interrad Medical ..... IntersectENT .... Intersense... Intersystems ... Intervalve.... InterVene .... Intevac.... Intra-Cellular Therapies ..... Intralase ...... Intralytix .... Intrexon ..... Intrinsic Therapeutics .... Intrinsity.... Introgen.... ... Intuitive Biosciences .... Intuitive Genomics ..... Intuitive Surgical.... Invenra .... Invensense .... Inventev ..... Inverness Innovations.... Invirsa ..... Invertix.... Invictus.... Inview Technology.... Inviragen.... Invisage Technologies .... ....InvisionHeart .... Invision Medical .... Invitae.... Invitrogen.... ...Invivosciences.... Invivo Therapeutics= Holdings .... Invuity.... Inx Medical.... IoGyn .... Iomai.... ... Iomed.... IOmet Pharma ..... Ion America Optics..... Ionic Materials ..... Ion Torrent.... Iovance Biotherapeutics ..... Iovation.... Iowa Thin Film.... Ipierian.... IPG Photonics.... ... Iquum ...Irhythm... iRobot... Iroko...Ironbridge.... ... Ironwood.... ... .... Irvine Sensors... .... biopolymer . .... Ischemia Care.... iSee ..... iSIGHT Partners ..... Isis.... Island Ddata.... Isogenis.... Isomark.... IsoPlexis .... Isoray.... Isothermal.... Isthmus Biosciences ..... IstoTechnologies.... itaconix.... I-Therapeutix..... Itherxm Pharmaceuticals.... Itraumacare... .. Itseez ..... Itzbig ..... Iwalk

Jade Therapeutics ..... J&Y ... Janssen Biotech .... Janus Biotherapuetics ... Javelin Pharmaceuticals ... Javelin Semiconductor ... JDP Therapeutics ..... Jennerex ... Jnana Therapeutics ..... Joule Biotechnologies .... Jounce Therapeutics .... Joyent .... Joylux .... Juno Therapeutics ..... Just Biotherapeutics

K2M .... K2 Therapeutics .... KAER Biotherapeutics .... Kala Pharmaceuticals ... Kaleido Biosciences ..... Kallyope ..... KaloBios Pharmaceuticals ..... Kalocyte .... Kalon Biotherapeutics ..... KalVista Pharmaceuticals .... Karius ..... Karuna Therapeutics ... Karyopharm Therapeutics ... Kateeva ..... Kayo Technology ..... KaZaK ... KC BioMediX ... KCI .... KDH Defense Systems ... Kebotix .... Keithley Instrument ... Kelyniam ... Kenall Manufacturing ..... Kensey-Nash ... Kent Displays ... Kentucky BioProcessing .... KeraNetics .... Keros Therapeutics ..... Kezar Life Sciences ..... KeyW .... Kilawatt Technologies ... Kindara .... KinDex ... KindHeart ..... KineMed .... Kinestral Technologies ..... Kineta ... Kinetic Concepts .... Kinex Pharmaceuticals .... Kingbright .... Kior ..... Kips Bay Medical ... Kite Pharma ..... Kitware ... Kiva Systems ... KLD Energy Technologies .... Klotho Therapeutics .... KMel Robotics .... Knightscope ..... Knome ... Knopp Neurosciences .... KNOW Bio ..... Know Labs .... KnuEdge .... Koam Engineering Systems .... Kodiak Sciences .... Kolltan Pharmaceuticals ... Komoku ... Kona Medical .... Konarka ... Koning ... Kopin .. KOR Electronics ... Koronis Pharmaceuticals ... Kosan Biosciences ... Kosmetikos .... Kovio ... KPI Therapeutics (from Kineta)... Kraig Biocraft ..... Kratos Defense & Security Solutions .... Kronos Advanced Technologies ... Krystal Biotech .... KSE ... KSQ Therapeutics ..... Kultevat ..... Kura Oncology .... Kumu Networks .... KVH .. Kylin Therapeutics ... Kyma ....Kymera Therapeutics ..... Kymeta ... Kyn Therapeutics .... Kyocera Solar .... Kypha ..... Kyras Therapeutics ..... Kyron Clinical Imaging .... Kytopen

LAAMScience ... LaBelle Associates ..... LabNow ...Laborie Medical Technologies ... Labrys Biologics ... Lacerta Therapeutics ..... Lactic Solutions ..... Laguna Pharmaceuticals (formerly ChanRx) ..... La Jolla Pharmaceutical ... Lake Shore Cryotronics .... Landec .... Landos Biopharma .... Lantern Pharma ..... Lantheus ... Lantos Technologies ... Lariat Biosciences .... Laser Design .... Lasergen ..... LaserMax ..... LaserMotive ... Laser Tissue Welding .... Lattice Biologics ..... Lattice Biotech .... Lawrie ... Lazarus Effect ..... LDR Holding ..... Lead Therapeutics ... LeafBio .... LeCroy ... LED Lighting Fixtures ... Lehigh Technologies .... Leica Microsystems ..... LetoSolutions .... Lexicon Genetics ... LexaGene ..... Lexicon Pharmaceuticals ... Leyden Energy ... Libra BioSciences .... LifeCell ... LifeGen Technologies ... Life Image ... LifeMine Therapeutics .... LifeSprout .... Life Technologies .... Ligand Pharmaceuticals ....Ligon Discovery ... Lightpointe ... Light Sciences Oncology ... LightWorks Optics .... Lilliputian Systems .... Lily Robotics ..... Linares Management Associates .. Lingotek ... Linnaeus Therapeutics .... LinQuest .... Lionano .... Lion Biotechnologies ..... Lipocine .... LipoScience ... Liquid Biotech ..... Liquidia Technologies ... Liquid Light ... Liquid Metal Battery ... LiquidPiston ... Liquid Robotics ... Liquid X Printed Metals .... LiQuifix ... Lithium Technology ... LiveData ... . LiveLeaf Bioscience .... LKC Technologies ... Locana.... Locus Biosciences .... Lodo Therapeutics .... Logical Therapeutics ... LogicBio Therapeutics ..... Logos Tech ... Lohocla Research ..... Lombard Medical ..... Longeveron ..... LonoCloud ..... Lookingglass ..... Loon Medical ..... Lotus Tissue Repair ... Loxo Oncology ... LPath Thera .... Lq3 Pharmaceuticals .... LS9 ... Luca Technologies .... Lucerno Dynamics .... Lucidux ... Lucigen .... LumaSense Technologies .... Lumena Pharmaceuticals .... Lumen Bioscience .... Lumencor ... Lumense .... Lumera ... Lumicell Diagnostics ... Luminar Technologies ..... Luminary Micro ... Luminex .... Luminus Devices ... Lumisyn ..... Lumitex ... LumiThera .... Lumos Pharma .... Luna Innovations ... Luna Technologies ... Lung Therapeutics .... Lutonix ... Luxtera ... Lycera ... LyGenesis ..... Lyncean ..... Lyndra Therapeutic ... Lynntech ... Lynx Biosciences ... Lyra Therapeutics ..... Lysosomal Therapeutics .... Lytro Therapeutics

M3 Biotechnology .... MabVax .... MacAulay-Brown ..... Macrochem ... MacroFab ..... Macrogenics ... Macrolide Pharma ..... Macrophage Therapeutics .... Madison Vaccines .... Madrigal Pharmaceuticals ..... MagBioSense ..... Magenta Therapeutics ..... Magic Leap ..... MagneMotion ... Magnesium Development ..... Magnetek ... Magnolia Medical Technologies .... Magnolia Optical Technologies ... Magnolia Solar ... Mainstay Medical International ...... Mainstream Engineering ... Major Pharmaceuticals .... Mako Surgical ... Manhattan Scientifics ..... Mantra Bio ..... >Manufcturing Techniques ..... MapInfo ...MAP Pharmaceuticals ... Mapp Biopharmaceuticals .... Marathon Pharmaceuticals ..... Marcadia Biotech ... Marina Biotech ... Marinus Pharmaceuticals ... Maritime Applied Physics .... Marrone Bio Innovations .... Martek Biosciences ... Mascoma ... Mashery ... Mason Box ... Masten Space Systems ... Masterson Industries .... Mast Therapeutics (formerly ADVENTRX) .... Material Sciences ... Material Technologies ... MathStar ... Mati Therapeutics .... Matouk Textiles ... Matritech ... Matrix Product Development .....Matrix Research .... Matrix Sensors ... Maverick Therapeutics .... MAX BioPharma ... MaxCyte ...... Maxdem ... Maxpower ... Maxygen .... Maze Therapeutics .... MBio Diagnostics .... MC10 .... MCube .... M Cubed Technologies .... MD Biosciences ..... MDSolarSciences ... Mebias Discovery ..... Mechanical Technology ... Mechanology ... Medafor ... Medarex ... MediBeacon .... Medicago USA .... Medical21 ..... Medical Cyberworlds .... Medical Device Logistics ... MedicaMetrix... Medgenics ..... MediciNova ..... Medicool Technologies .... MedImmune .. Medina Medical .... Mediomics .... Medior Therapeutics .... Medis ... MEDITE Group .... Medivation ... Mednology Solutions .... Medrobotics ... MedShape .... MedSocket (formerly 1CDS) ...... Medsphere Systems ..... MedTel ..... MEI Pharma ..... Meka .... MELA Sciences .... Melinta Therapeutics .... Melior Discovery .... Memjet ...Memry ... Memsic ... MEMS Optical...Menlo Therapeutics ..... MER ... Mercator Therapeutics ... Mercury Computer Systems .... Merganser Biotech .... Merge Technologies ... MeriaGTx ..... Meridian Bioscience ... Meritage Pharma ..... Merkatum ... Merrimack Pharmaceuticals ... Meryx .... Mersana Therapeutics ... Mesa Photonics ... Mesocopic Devices ... Metabasis ... Metabiota .... Metabolic Solutions Development .... Metabolex .... Metabolix ... MetaCarta ... Metacrine .... Metactive Medical ..... Metal Oxygen Separation Technologies ... Metamark Genetics ... MetaModix ... Metavention ..... Metompkin Seafood .... MetroLaser ... MGC Diagnostics ... MIACH Orthopaedics ..... Misaole .... Micell Technologies ... Michelman ... Micracor .... Micrel ... MicroCoating ... Micracor .... Microbe Detectives ... Microbia ... Microbot Medical ... Microfluidics International (Microbia) ... MicroGreen Polymers .... MicroIslet ... Microlin Bio .... MicroMask ... Micronics ... MicroOptical (New Mexico)... MicroOptical (Massachusetts) ... MicroOptx ..... MicroPower Technologies ... MICROrganic Technologies .... MicrowSat Systems .... Microscopy Innovations ..... Microstaq ... MicroTransponder ..... Microvision ... MicuRx Pharmaceuticals .... Midori Renewables ..... Mid Valley Industries ... Millendo Therapeutics (born as Attercor) ..... Million Concepts ..... Miltec .... MiMedx Group .... MimiVax .... Minerva Biotechnologies ... Minerva Neurosciences .... Minerva Surgical .... Minimally Invasive Devices .... Minnesota Thermal Science ..... Minnetronix ... MIOX ..... Mirador Biomedical ... Mira Dx ... MiRagen Therapeutics ..... Miramar Labs .... Mirati Therapeutics ..... miRecule .... Mirimus ... Mirina ... Mirna Therapeutics.... Miromatrix Medical ... Mirus Bio ....Mirum Pharmaceuticals ..... Mission Bio ..... Mission Research ... Mississippi Polymer ... Mithridion ... Mitochon Pharmaceuticals ..... Mnemosyne Pharmaceuticals ... Mobile Robots ... Mobius Therapeutics ..... Moderna Therapeutics .... Modern Meadow .... Modern Technology Solutions .... Moduline Systems .... Modumetal ..... MOgene Green Chemicals .... Molecular Biometrics ... Mohawk Innovative Technology ..... Molecular Detection ... Molecular Diagnostics .... Molecular Imprints ... Molecular Insight Pharmaceuticals ... MolecularMD ... Molecular Sensing ... Molecular Templates .... Moleculin Biotech ..... Molten Metal .. MoMelan Technologies ... Momenta Pharmaceuticals ... Monebo ... Monogram Biosciences .... Monteris Medical ..... Morphic Therapeutics ..... Morphormics ... Morphotek ... Morris Innovative Research ... Mortara Instrument ... MortaSecurity .... Motif ... Motricity ... Motus Therapeutics .... Mound Laser & Photonics Center ..... Movia Robotics ..... Moximed .... MPP Group ... MPSP ... MSNW .... Mudawar Thermal Systems ..... Munksjo Paper ... Muons ... Muse bio .... Myco Technology .... Myocor ... MyoKardia ... Myomo ... Myonexus Therapeutic ..... Myovant Sciences ..... Myriad Genetics ... Myriant Technologies ... Mystic Pharmaceuticals

N12 Technologies ... (N30 Pharmaceuticals) now Nivalis Thera .... NABsys ... Nalas Engineering .... Nammi Therapeutics ..... NanOasis Technologies ... NanoBio ... Nanobiosym ... Nano-C ... NanoCellect (formerly NanoSort) ..... Nanocomp Technologies ... NanoCoolers ... Nanocopoeia ... NanoCor Therapeutics ...Nanodynamics (Buffalo) ... Nano DX ..... Nanodynamics (NYC)... NanoeXa .... Nanofiber Solutions ... Nanogen ... NanoGraf (formery SiNode) ..... NanoGram .... nanoGriptech ..... NanoGuard Technologies .... NanoH2O ... Nanohmics ... NanoLab ... NanoLite Systems ... NanoLogix ... NanoLumens ..... Nanomaterials Research ... NanoMatrix ... NanoMedex ... NanoMedicalSystems ... NanoMedical Systems .. Nanomix ... nanoMR ..... Nanophase Technologies ... NanoPhotonica ... Nanopore Diagnostics ..... Nanoptek ... Nanoramic Laboratories (formerly FastCap Systems) ..... nanoRETE .... Nanoscale Components ... Nanoscale Materials ... Nanosolar ... Nanosonic ... Nanospectra Biosciences .... Nanosphere ... NanoSteel ... Nanostim .... NanoString Technologies .... Nanosys ... NanoSystems ... Nano Tailor ... Nanotek Instruments ..... Nano-Terra ... Nanotherapeutics ..... NanoTune Technologies ... Nanova .... Nanovation Technologies ... NanoVault Medical .... NanoVibronix ... NanoViricides ... NanoVision Diagnostics .... NantCell ..... Nantero ... Napo Pharmaceuticals ... NantKwest ..... Narus Biotechnologies ..... Nascentric ... Nastech Pharmaceutical ... Natera .... National Technical Systems ..... Natural Molecular Testing ..... NaturalNano ... Nature's First ..... Natus Medical ... Naverus ... Navidea Biopharmaceuticals ... Navini Networks ... Navire Pharmaceuticals .... Navitor Pharmaceuticals .... Navmar Applied Sciences ... NBD Nanotechnologies ....NCD Technologies .... nContact Surgical ... Neah Power ... Near Infinity .... Neato Robotics ... Nektar Therapeutics ... Nekton Research .... NemaMetrix .... NeoChord ... Neogen .... NeoGenomics ..... Neograft ..... NeoLight ..... Neon Therapeutics .... NeoPhotonics ... Neoprobe ... Neos Therapeutics ..... NeoSync ..... Neothetics .... Neotron ... NephroGenex .... Nereus Pharmaceuticals ... Nest .... Netcentric .... Netezza ... NetLogics Microsystems... Netspeed Systems ...... Net Watch Solutions ..... NetworkFab ... NeurAccel Biosciences ... Neurala .... Neural Analytics .... Neuralstem .... Neuraly ..... Neuraptive Therapeutics ..... Neuro Amp .... Neurobiological Technologies ... NeuroChaos Solutions .... Neurocrine Biosciences ... NeuroDx Development ... NeuroEM .... Neurodyne Medical ... Neurofluidics ....Neurogastrx .... Neurogen ... NeurogesX ... Neurognostics .. NeuroHabilitation .... NeuroLogica .... NeuroLutions ..... NeuroMap ... Neuro Kinetics .... NeuroMetrix... Neurona Therapeutics .... Neuronetics . Neuronex .. NeuroOne ..... NeuroPace ... NeuroPhage Pharmaceuticals ... Neuron Systems ... NeuroPointDX ..... Neuroptix ... Neuroscience .... NeuroSigma .... NeuroTek .... Neurotrack .... NeuroTronik .... Neurotrope ..... Neurovance ... NeuroVigil ... Neurovascular Diagnostics ..... NeuroVision Imaging .... NeuroVista .... NeuroVive .... NeuWave Medical ...Nevro ... New Dominion Enterprises ..... NewLeaf Symbiotics .... NewLink Genetics .... Newlink genetics england ... biolabs ... new era technology ... New Haven Pharmaceuticals ... Nexant ...Nexbio ... NexImmune .... NexPlanar .... NextCODE Health .... NextCure ..... Nextio .... NEXTracker ....Nextreme Thermal Solutions ... NextStep Robotics ..... Nexus Biosystems ..... NG1 Technologies .... NGM Biopharmaceuticals .... Nico ..... Night Vision ... Nimblegen Systems ... Nimble Storage .... Nimble Therapeutics .... Nimbus Discovery ... Nimbus Therapeutic ..... Ninepoint ...Niowave ... NIRvana Sciences .... Nitero.... Nitric Biotherapeutics ....Nitricgen ... Nitride Solutions .... Nitrogenics ..... Nitromed ...Nitronex ... Nivalis Therapeutics formerly N30 Thera ..... NKT Therapeutics ... Nlight ... NMT Medical .... Noah Technologies .... Noble Fiber ... Nocion Therapeutics .... Nohla Therapeutics .... Noivatone .... Nok Nok Labs .... Nomadics .... NONA Composites .... Noninvasix .... Nonvolatile Electronics .... Nora Therapeutics .... Norian ... NorMedix ..... Normoxys .... Norse .... Northeast Photosciences ... Northstar Medical Radioisotopes .... Northstar Photonics... Northwest Biotherapeutics .. Norwich Technologies .... Nostopharma .... Notice Ttechnologies ... .Novacea ... Novalar Pharmaceuticals ... Novalux ... Novan Therapeutics .... NovaScan ... Nova Synthetix .... Novatek ... NovaTorque ... NovaTract Surgical ... Novavax .... Novazyme Pharmaceuticals ..... Novecon Technologies ... Novella Clinical .... Novelos Pharmaceuticals ... Novelos Therapeutics ... Noveome Biotherapeutic ..... Novian Health .... Novira Therapeutics ... Novocell ... Novogy ... Novomer ... Novophage ... Novo Sol-u-tions MD .... Novosource ... Novozymes .... Novus Biologicals .... Noxilizer ... Nox Technologies ... NP Photonics ... NPS Pharma ..... NRGindependence ..... NSS Labs ..... Nucelis .... Nuclea Bioechnologies ... Nufern .... NuGEN Technologies ..... NuMat Technologies ..... NuMedii .... NumereX .... NUMiX Materials ..... NuPathe .... Nurel (now PeriphaGen) .... Nurix Therapeutics ... Nuron Biotech ... Nutrabiotix ... Nutrient Recovery and Upcycling .... NuVant ... Nuvaira .... NuVascular Technologies .... Nuve ..... Nuventix ... Nuvera Biosciences ... Nuvera Fuel Cells.. . Nuvotronics ..... Nuvox Pharma ..... Nu Waves ..... NxThera ... Nvision Biomedical Technologies ..... NZ Applied Technologies

Oak-Mitsui .... Oasys ... ObjectVideo ... Obsidian Therapeutics ..... OBS Medical ... Ocarina Networks ... Ocata Thera ... Occipital .... Ocean Power Technologies ... Ocean Renewable Power .... Ocera Thera .... OCI ... Ocugen ..... Ocular Therapeutix .... Oculeve ... Oculogica ..... Oculus ... Oddpost ... Odyssey Systems Consulting Group ... Oil Chem Technologies ... OLEDWorks .... Omeros ... OmniGene Bioproducts ... OmniGuide ... OmniLytics ... Omniox ..... OmniSonics Medical Technologies ... Omnis PharmaRebiotix .... Omni Water Solutions ... Onboard Dynamics .... ONCE Innovations ..... OnChip Power .... Oncobiologics ..... OncoCyte .... Oncogenex ... Oncolmmune ..... Oncolinx .... Oncolix ..... Oncolytics Biotech ... OncoMed Pharmaceuticals .... OncoNano Medicine .... Onconova Therapeutics ...Oncoscope ... OnCore Biopharma ..... OncoResponse ..... Oncorus ..... OncoSec Medical .... OncoTartis ...... Oncothyreon ... Oncovista Innovative Therapies ..... Oncternal Therapeutics ... Onduo ..... One Resonance Sensors .... Onexio Biosystems .... Onko Solutions .... ONL Therapeutics .... On-Q-ity .... Onspira Therapeutics .... On Target Laboratories .... Ontela ..... On-X Life Technologies .... Onyx Pharmaceuticals ... Oorja Protonics .... Open Algae ... Open Monoclonal Technology ..... Open Silicon ... OpenWater Power .... Opertech Bio ..... Opexa Therapeutics ... OpGen ... OPNET Technologies ... Opsonix .... OptTek Systems ... Optelecom ...Optelecom-NKF ... Optherion ... Optical Concepts .. Optigain .. Optimal Technologies ... Optimus Technologies .... OptiNose .... Optivision ... Optofluidics ... OptoLum ..... Optonicus .... Opto Technology ... Optomec .... OPX Biotech ... Oragenics .... OraMerix ... Orasi Medical ... OraSure Technologies .... Orbital Technologies ... Orbotix .... Orchard Therapeutics ..... Orchestra BioMed .... Orchid Cellmark ... Oregon Iron Works .... Orexigen Therapeutics ... Organic Research .... Organogenesis ... Organovo .. ORIC Pharmaceuticals ..... Oricula Therapeutics .... Origin Medsystems ..... OriginOil ... Orion Energy Systems ... Orion Genomics ... Ormet Circuits ... Orologic... OrphoMed ..... Ortel ... OrthoAccel Technologies ... Ortho Kinematics .... Oryx Technology ...Oscient Pharamceuticals ...Oscilla Power .... Osiris Therapeutics ... OSI Pharmaceuticals ... Oso Biopharmaceuticals Manufacturing .... Osprey Medical .... Ossianix ... OSSIO ..... Ostendo Technologies ... Osteotech ... Osterhout Design Group .... OtoNexus Medical Technologies .... Otonomy .... OtoSense .... Ottomatika .... Outset Medical .... OvaScience ... >Ovid Therapeutics ..... Oxalo Therapeutics .... Oxford Performance Materials ... Oxis International .... Oxygen Biotherapeutics

P3I ... Pace Packaging .... Pacific Biosciences .... Padlock Therapeutics .... Pain Therapeutics ... PaizaBio .... Palvella Therapeutics ... Palantir Technologies .... Palleon Pharmaceuticals .... Palmaz Scientific ..... Palmer Labs ... Paloma Pharmaceuticals ... Panacea Solutions .... Panacos ... Pandion ..... Pandromics ..... Pan Genome Systems .... Panomics ..... PanTheryx .... Paper Battery .... PapGene .... Parabricks .... Paradigm Diagnostics .... Paradigm Sensors ... Paradromics ..... ParaGen Technologies ..... Paragon Bioservices ..... Paragon Dynamics ... Paragonix Technologies .... Parasol Therapeutics ... Paratek Pharmaceuticals .... Parexel International .... Parhelion .... Parion Sciences ... ParkerVision .... Partner Therapeutics ..... Partpic .... Passage Bio ... Passport Systems ... Pasteuria Bioscience ... Pathfinder ... PathoGenetix ... PathoVax ..... Pathway Genomics .... PatientStream ... PatientWise ... Patton Medical Devices ... Patton Surgical .... Pavilion Technologies ... Pax Streamline ... PaxVax ... PDI Therapeutics ..... PDL BioPharma ... PDS Biotechnology ..... Pearl Therapeutics ... Pear Therapeutics ..... PECA Labs .... Pediatric Bioscience .... Peerless Technologies .... Pegasus Sustainability Solutions .... Pelican Products ..... PellePharm .... Pellion Tech ... Peloton Therapeutics ..... Peninsula Pharmaceuticals ..... PennAlt Organics ..... Penumbra ..... PeproMene Bio .... Peptimed ... Peptilogics .... Peptimmune ... Perceptive Navigation ..... Perceptive Sciences ... Perceptron .... PercipEnz Technologies ... Peregrine Semiconductor .... PeriphaGen .... Permeon Biologics ... Perosphere .... Perscitus Biosciences ... Perseon ..... Persimmon Technologies .... PersonalBee ... Personalis ...... Personal Genome Diagnostics .... Pervasis Therapeutics ... Pervasive .... Petra Pharma ..... Pfenex ... Pharmacyclics .... PharmaJet .... PharmAkea Therapeutics .... Pharmasset ... PharmAthene ... PharmatrophiX .... PhaseBio Pharmaceuticals .... Phase Bioscience ... PhaseRx .... Phigenix ..... Phoenix (formerly Phoenix Nuclear Labs) ..... Phoenix Biotechnology .... Phoenix Nuclear Labs ... Phoenix Science .. Phononic Devices ... Photobit ... Photolitec ..... PhotoMedex ... Photonics Innovations ... Photon-X .... PhotoSonix Medical .... PhotoThera ... Photronics ... Phoundry Pharmaceuticals .... Phraxis .... Phrixus Pharmaceuticals ..... Phurnace Software ... PhylloTech ..... Phylonix .... Phylos Bioscience ..... Physcient .... Physical Optics... Physical Sciences ... PhysioGenix ... PhysioSonics ... PhytoTech ... Picolight .... Picometrix ... Piedmont Biofuels .... Pieris Pharmaceuticals ..... Pika Energy ... Pilus Energy .... Pinger ... Pinnacle Technology ... Pioneer Surgical Technology .... Pionyr Immunotherapeutics ..... Pivot Bio ..... Pixelligent .... Pixel Optics .. Pixim ... Pixtronix ... Plakous Therapeutics ..... Planar Energy ... Planar Systems ... Planet Labs .... Plano Microwave ..... Plasan ... PlasmaTech Biopharmaceuticals .... Platelet BioGenesis .... Platypus ... Play-i .... PLC Medical Systems ... Plextronics ... Plexxikon ... Pliant Therapeutics .... Plug Power ... Pluromed ... PLx Pharma ..... PLX Technology .... PMT .... PMV Pharmaceuticals .... PneumRx ..... Point Source .... Polarean ..... Polatis .... Polychromix ... Polyera ... PolyMedica ... PolyMedix ... Polymer Technology Systems ... Polynoma ..... PolyNova .... PolyPlus ... PolyRemedy ... Polysciences ... Polystor ... Portola Pharmaceuticals ... Poseida Therapeutics .... Possis Medical ... Pothole Pros ... PowerGenix ... Powerlight ... Power Precise Solutions ... PowerVision ... Pozen ... PQ Bypass .... Prairie Technologies ..... Pranalytica ... Praxis Biotechnology ..... Precipio ... Precision Biopsy ... Precision BioSciences .... Precision for Medicine .... Precision Genome Engineering .... Precision Ocular Metrology ..... Precision Optics ... Precision Therapeutics (now Helomics) .... Precision Virologics .... Predictive Biosciences ... Pregmama ..... Presage Biosciences ... Presidio Pharmaceuticals .... Pressure BioSciences ... PreTalen ..... Prevail Therapeutics ..... Preventice ..... Prevention Pharmaceuticals .... Prieto Battery ..... Primary Data ..... Primera Biosciences ... Primordial .... Primorigen Biosciences ... Primus Power .... Princeton Satellite Systems ..... Principia Biopharma .... Prism Solar Technologies .... Procept BioRobotics ..... ProCertus BioPharm ... Processa Pharmaceuticals ..... Proclara Biosciences (formerly NeuroPhage Pharmaceuticals) .... Procyrion .... Profectus BioSciences . .. Progenics Pharmaceuticals ... Progenity .... Progeny Systems ..... Prologic ... Promedior ... Promega ..... Promentis .... Prometheus Laboratories .... Pronutria ..... Propagenix ..... Propeller Health .... Propulsive Wing .... ProstaGene .... Protagonist Therapeutics .... Protein Foundry ..... Protein Sciences ... ProteinSimple (formerly Cell Biosciences) .... Proteon Therapeutics ... Proteostasis Therapeutics ... Proteotech ... Proteus Biomedical ... Proteus Digital Health .... Protez Pharmaceuticals .... Prothena .... ProThera Biologics ... Proto Labs ... Proton Energy Systems ...Protonex .. Prototype Productions .Provagen ... Provenance Biopharmaceuticals ... Provention Bio .... Proventys ... Provista Diagnostics .... Pryor Medical Devices ..... PsiKick ..... pSivida ... PTC Therapeutics .... Pulmatrix ... Pulmonx .... Pulmotect ..... Pulse Aerospace .... Pulse Electronics .... PulseTherapeutics .... Puma Biotechnology ..... PUR Biologics ..... Pure Bioscience .... Purfresh ... Purillume ..... Pursuit Vascular ... PurThread .... PvP Biologics

Qcept Technologies .... Qcue .... QD Vision ... QED ... qFuzion ..... Qioptiq ... QM Power ... Qpex .... QPixel ... QR Pharma ... QSpex .... Qteros ... QuaDPharma .... Quadra-Aerrow International ... Quadraspec ... Quad Technologies .... Qualcomm ... QualityMetric ... Qualtech Systems .... Qualtré ... Quanterix ... QuantRx Biomedical .... Quanttus .... QuantTera .... Quantum Circuits ..... Quantum Epitaxial Designs ... Quantum Fuel Systems... Quantum Logic Devices ... Quantum Materials .... QuantumSphere .... Quantum Xchange .... Quark Biotech ... Quark Pharmaceuticals ... Qubitekk ..... Quentis Therapeutics ..... Quick–Med Technologies .... Quid ..... Quidel ... Quincy Bioscience ... Quintessence Biosciences ... Quorum Systems

Radant Technologies ... Radiabeam Technologies ... Radiance Technologies .... Radiant Photonics...Radiation Monitoring Devices ... RadioMedix ... Radius Health .... Rafagen ... Rainbow Organic Farms ... RainDance Technologies ... RainStorm ... Rain Water Solutions ... Rallybio ..... Raland Therapeutics .... RaNA Therapeutic ... RAN Biotechnologies .... Range Fuels ... Rapamycin Holdings ..... RaPharmaceuticals ... Rapid Diagnostek ... Rapid Micro Biosystems ... Rapiscan ... RareCyte ..... Raser Technologies .... Raydiance ... Raydiant Oximetry .... Raymond .... Raze Therapeutics .... RE2 .... Ready Robotics ..... Reata Pharmaceuticals .... Rebellion Photonics .... Rebion ..... Rebiotix .... Receptor Logic ... Receptos ..... Recodagen ... Recombinetics ... ReconRobotics .. Recovery Engineering ..... Recro Pharma .... Recursion .... Redox Power Systems .... Red Rock Biofuels .... RedShift BioAnalytics .... Redwood Robotics .... RedZone Robotics .... RefleXion Medical .... Refuge Biotechnologies .... Regado Biosciences ... ReGear Life Sciences ..... ReGen Biologics ... Regenerative Medical Solutions ..... Regenerative Sciences ... Regentys (formerly Asana Medical) .... Regenxbio .... Regulus Therapeutics ... Rehabtics .... Relay Therapeutics ..... ReliantHeart .... ReliefBand Technologies ..... Relievant Medsystems ..... Relypsa .... Remedy Plan Therapeutics .... Remedium Technologies ... RemoteReality .... Rempex Pharmaceuticals .... Renaissance Services ..... Renegade Materials .... Reneo Pharmaceuticals ..... Renerva ..... ReNeuroGen .... Renewable Alternatives ... Renewable Energy Group .... Renmatix ..... RenovoDerm ..... Renovia .... Renovion .... Renovis ... Rentech ... Replidyne ... Repligen .. Replimune Group .... Research Frontiers .. Research Innovations ..... Resolve Therapeutics ... Resolvyx Pharmaceuticals ... Resonetics ..... Respicardia ... Respira Therapeutics .... Response Genetics ... Restoration Robotics ..... resTORbio ..... Restore Medical ... Retectix ..... Retek ...Rethink Robotics ... Retia Medical .... Retriever Technology .... RetroSense Therapeutics ..... Reva Medical ... Revance Therapeutics Pharmaceutical .... Revegen ... ReVision Optics .... ReVision Therapeutics .... Revitope Oncology ..... ReVivo Medical .... RevMedx .... ReVolt Tech ... Revolution Medicines .... ReWalk Robotics (Israel) .... Rexahn Pharmaceuticals ... Rex Computing ..... RF Code ... RFMicron .. RFS Pharma ..... RF Surgical. .... Rgenix .... Rhenium Alloys .. Rheos Medicines ..... Rheostat Therapeutics ..... Rheumco .... Rhevision ... Rho ... Rhythm Pharmaceuticals ... Rhythmia Medical ... Ribometrix .... RiboNova .... Ribon Therapeutics ..... Rib-X Pharmaceuticals ... Rice Technology ..... Ridgetop Group ... Rigel Pharmaceuticals .... RightEye ..... RightHand Robotics .... Rinat Pharmaceuticals .... Rinovum Women’s Health ..... Rio Grande Neurosciences ..... RipCode ... Rite Solutions .... Ritter Pharmaceuticals ..... River Vision Development ..... Rive Technology ... RJA Dispersions ... R.L. Phillips ... RMH Sciences ... Robb Surgical Devices .... Robopsy ... Robotic FX ... Robotics VISION Technologies ..... Robotic Technology ... Rocket Pharmaceuticals .... Rockwell Medical ..... Rocky Research .... Rodeo Therapeutics ..... Rodin Therapeutics ... Roka Bioscience ..... RoosterBio .... RootPath .... Rosina Food Products .... Ross Valve ..... Rotational Medical .... RotoMetrics ..... RoverMed Biosciences ..... Rowbot Systems .... Royole ..... RQx Pharmaceuticals .... RRE Solar .... Rubicon Tech ... Rubigo Therapeutics .... Rubitection ..... Rubius Therapeutics .... RubrYc Therapeutics ..... Rules-Based Medicine ... Rushford Hypersonic ... Ruud Lighting ..... RxFunction ... RXi Pharmaceuticals ... RxMedic .... Rypos

S2 ... Sadasis .... SafeShot .... Saffron Technology .... Sage Electrochromics ... SADAR 3D .... Sage Science ... Sage Therapeutics ...Sakti3 ... Salarius Pharmaceuticals ..... Salient Surgical Technologies ... Salix Pharmaceuticals ... Salutaris Medical Devices ..... SAM Medical .... Sancilio Pharmaceuticals .... Sand 9 . .. Sandia Biotech .... Sangamo Biosciences ... Sangart ... Santalis Pharmaceuticals ..... Santarus .... Sanuwave Health .... Sapheon .... Sapphire Energy .... SARbarcode .... Sarda Technologies ... Sarepta Therapeutics .... SatCon Technology ... Satori Pharmaceuticals .... Savara Pharmaceuticals .... Savi ... SBH Sciences ... Scanadu ..... Scholar Rock .... Sciaderm ..... SciClone Pharmaceuticals ... Sciencescape ..... Scientific Conservation .... Scientific Research ... Scientific Solutions ... Scientific Systems ... SciFluor Life Sciences ... Scilex Pharmaceuticals .... Scinovia ..... Scioderm .... SciQuest ... Scopic Software ... Scout Bio .... Scynexis ... SD Catalyst Group ... SDL .. SeaChange ... Seacoast Science ... Seahawk Biosystems ... Seahorse Bioscience ... Seaside Therapeutics .... Seattle BioMed ..... Seattle Genetics ... Seattle Medical Tech .... Sebacia .... Second Genome .... Second Sight Medical Products ... Securboration ..... Secure Computing ... Sedia Biosciences ..... Seeo ....Segetis ... S.E.G-WAY Orthopaedics .... Seldon Labs ... Selecta Biosciences ... SELLAS Life Sciences Group .... SeLux Diagnostics .... Sema4 Natalis ..... Semiconductor Laser ... SemiProbe ... Semler Scientific .... Semma Therapeutics .... Semnur Pharmaceuticals .... Semprius ... Semprus BioSciences .... Sencera International ... SenesTech ..... SenGenix .... Senior Scientific ..... Seno Medical Instruments .... Senomyx ... SensAble Technologies ... Sense .... Sense Diagnostics .... Senseonics ..... Sensintel .... Sensiotec ... Sensors Unlimited ... SensorTran ... Sentelligence ... Senti Biosciences ..... Sentient Technologies ..... SentreHEART ..... Sepracor ... SeprOx .... SeQual Technologies ... Sequella ... Sequel Pharmaceuticals .... Sequenom ... Sequenta ... Sequent Medical .... SeraCare Life Sciences ... Seragon Pharmaceuticals .... Seraxis ..... Seres Therapeutics (formerly Seres Health) .... Serenex ... Sermonix Pharmaceuticals .... Servergy ..... SetPoint Medical .... Seurat Therapeutics ..... Seventh Sense Biosystems ... SGB Biofuels ..... SGX Pharmaceuticals ... Shamrock Energy ... Shape Pharmaceuticals ..... Shape Security .... Shapeways .... Sharklet Technologies ..... Sharp Edge Labs ..... Sherlock Biosciences Shift Labs ..... Shift Pharmaceuticals ..... Shiloh Labs ....Shine Medical Technologies ... Shore Thing Shellfish .... Shuttle Pharmaceuticals ..... Si-Bone .... Sicel Technologies ... SiCortex ... Sideris Pharmaceuticals ..... SI Diamond Technology .... Sienna Biopharmaceuticals ..... Sierra Energy ..... Sierra Monolithics ... Sierra Nevada ... Siga Technologies ... SiGe Semiconductor ... Sigilon Therapeutics .... Sigma Labs (NM) .... Sigma Technologies .... SignalFX (formerly Signal Fuse) ..... Signal Genetics .... Signature Genomic Laboratories ... Sila Nanotechnologies .... Silarus Therapeutics .... Silatronix .. Silent Power ... Silicon Biosystems Menarini ..... SiliconBlue .... Silicon Laboratories ... Silicon Mountain Design .. Silicon Space Technology .... Silk .... SilkTech Biopharmaceuticals ..... Silk Tech .... Siluria ... Silverbrook ... Silverback ..... Silvergate Pharmaceuticals .... Silver Spring Networks ... Simbol Materials ... Simply Incredible Foods ... SiMPore ... Simulation Technology and Applied Research ... Simulution ... Singlera Genomics ..... Singulex ... Sinmat ... SiNode Systems ..... Sintact Medical Systems ..... Sion Power ... SiOnyx ... Sioux Manufacturing ... Sirga Advanced Biopharma .... Sirion Therapeutics ... Sirnaomics ..... Sirna Therapeutics ... Sirtris Pharmaceuticals ... Sisu Global Health ..... Sitari Pharma ..... Skybox Imaging .... Skyhawk Therapeutics ..... Skyline Medical .... Skyonic ... SLI .. SLIPS Technologies ..... SmartCells ... Smart Modular Technologies ... SmartSpark Energy Systems ... Smart Structures .... Smart Wires ..... SmartZyme BioPharma .... Smisson-Cartledge Biomedical ... Smooth-Stone ... SNP Bio ..... Socrates Health Solutions .... Soft Machines .... Soft Robotics ..... SoftSwitching Technologies ... Soft Tissue Regeneration ... Soladigm (now View) ..... SolAero Technologies ..... Solaicx .... Solais Lighting .... Solana Surgical ..... SolaranRx ..... SolarBridge Technologies ... Solar Connection .... Solarea ..... Solaria ... Solarmer Energy ... Solar Power Technologies ... SolarWinds ... Solazyme ... Solexant ... Solexel ... SolFocus ... Soliant ... Solid Biosciences .... Solid Concepts ..... SolidEnergy .... Solidus Biosciences ..... SolidWorks ... Soliris .... Soliton ..... Solixia ... Solix Biofuels ... SolMap Pharmaceuticals ... SoloHealth ... Solomon Technologies ... Solo Power .... Solstice Biologics .... Soluble Therapeutics .... Solx .... Solyndra ... Soma .... SomaDetect .... SomaLogic .... Somatic Labs ..... Somaxon Pharmaceuticals .... Somerset Therapeutics .... Somna Therapeutics ... Sonalysts ... Soneter .... Sonex Aircraft ... Sonitus Medical ... Sonivate ..... SonoSite ... Sonovex .... Sontra Medical ... Sonus Pharmaceuticals ... Sophiris Bio .... Sophono ..... Soraa .... Sorrento Therapeutics .... Soteira ... Sostena .... Sotera Wireless ... Sound Pharmaceuticals ..... Sourcefire ... Source MDx ... Southwall Technologies ... Southwest Windpower ... Space Dev ... Spaltudaq ... Spansion .... Sparkbuy ..... SparkCharge .... Spark Therapeutics .... Sparo Labs ..... Spatial Photonics ... SPEC ..... Spectra254 .... Spectragenetics .... Spectral Energies ..... Spectral Systems ..... Spectranetics ... SpectraWatt ... Spectro Coating ... SpectrumS4 .... Speech Tails ... Speer Medical .... Spero Therapeutics ..... Spinal Modulation ..... Spinal Restoration ... Spinal Simplicity ..... Spinal Stabilization Technologies ..... SpineEX .... SpineGuard ... Spineology ... Spine Wave .. Spintech .... Spin Transfer Technologies .... SpiralGenetics .... Spiral Therapeutics .... Spiration ... Spire ... Spirox (formerly Nasoform) ..... Spoonflower .... Spotfire ... Spot On Sciences ... Spredfast ... Spring Bank Pharmaceuticals ... SpringLeaf Therapeutics ... SpringWorks .... SpringWorks Therapeutics .... SPR Therapeutics .... Spyrix ....SQZ Biotech ..... SRL ... Staktek Holdings ... Standard Bariatrics .... STAR Cryoelectronics ... Starfire ... Startech Environmental ... Startup Circle Pharma .... StarVision Technologies .... Stasys Medical ..... SteadyMed Therapeutics ..... Stealth BioTherapeutics ..... Stealth Therapeutics ... Steel City Optronics .... Stellaray .... Stellar Biotech .... Stellar Science .... Stellent .... Stemagen ... StemBioSys .... Stem Cell Assurance (Now BioRestorative Therapies) .... StemCells ... Stemcentrx ..... StemCo Biomedical ... Stemgent ... StemImmune .... Stemina Biomarker Discovery ... Stemonix ..... Stem Pharm .... Stereotaxis ... Sterilmed ...... Sterling Semiconductor ..... StimMed ..... Stirling Energy .... Stoke Therapeutics ..... Stottler Henke ... Straight Flight .... Stratagene ... Strata Oncology ..... Stratasys ... Stratatech ... Strategic Response Initiatives .... Stratos Genomics ... Strella Biotechnology ..... Stromedix .... Strongbridge Biopharma ..... Sucampo Pharmaceuticals ..... Summit Technology .... Sun BioPharma ..... Sun Catalytix .... Sunesis Pharmaceuticals .... SunHealth Solutions ... Suniva .... Sunovion Pharmaceuticals ... SunPower ... Sun Power Biodiesel ... Sunrise Ridge Algae ....Sunshine Heart .... Suntech ... Suono ..... Superconductive Components ... Superconductor Technologies ... SuperDimension ... SuperFlex ..... Superior Organoid Technologies ..... Supernus Pharmaceuticals .... SuperPower ... Superprotonic .... SupraSensor ..... Surefire Medical .... Surface Logix ... Surface Oncology ..... Surgient ... SurgiQuest .... Surmet ... SurModics ... Suro Biopharma ..... Suros Surgical Systems ..... Surrozen .... SURVICE Engineering ..... Sustainable Bioproducts .... Sustainable Oils .... SustainX ... Sutro Biopharma ..... Sutron ..... SutroVax ..... SuturePro Technologies (now Ceterix) .... SuviCA .... SuVolta ... Suzlon Rotor ... SVS ... SPEC ... Swallow Solutions .... SweetSpot Diabetes Care ... Swift Biosciences .... Syagen Technology ... Symbiomix Therapeutics ..... Symbiont Web ... Symbotic ... Symetrix .... Symic Biomedical ..... Symyx Technologies ... Synack .... Synageva BioPharma ... SynAm Vaccine .... SynapDx .... Synaptics ... SynCardia Systems ..,.. Synchroneuron .... SynchroPET .... Syndax Pharmaceuticals ... Syndexa Pharmaceuticals .... Synedgen .... Synergy Biomedical .... Synergy Pharma ..... SynGen .... Synlogic ..... Synopsys .... SynSonix .... Synta Pharmaceuticals ... Syntax-Brillian ... SyntheMed ... Synthetic Biologics ..... Synthetic Genomics .... SyntheZyme ..... Synthorx .... Syntimmune ..... Syntrix Biosystems .... Syntronics .... Synvitrobio ..... Syros Pharmaceuticals .... Sysgain .... Syslogic .... Systagenix Wound Management ..... Systems and Processes Engineering SPEC ... Systima Technologies ..... Sytera

T2 Biosystems ... T3D Therapeutics ..... Tabula ... Taconic BioSciences ..... Tactical Engineering and Analysis ..... Tactile Systems Technology .... Tactiva Therapeutics ..... TAI Diagnostics ..... Talaris Therapeutics .... Talecris Biotherapeutics ... Talee Bio ..... Taligen Therapeutics ... Talima Therapeutics ... Tal Medical ... Talon Therapeutics ... Tandem Diabetes Care ... Tangen Biosciences ..... Tango Therapeutics ..... Tanox ..Tantaline .... TapImmune .... Tarari ... .Targacept ... TargeGen ... Targ-Anox ... Targanta ... Targazyme (formerly)America Stem Cell.... Targeson ... Targeted Genetics ... Targeted Growth ... Taris Biomedical .... Tarveda Therapeutics ..... Tascent .... Tauriga Sciences .... Taxa Biotechnologies ..... Taxon Biosciences .... Taxus Cardium (formerly Cardium Therapeutics) ... Taylor Devices ..... TCR² Therapeutics ..... TDA Research .... Tealium ..... TearScience ... TearSolutions .... Tech-X .... Techniscan Medical Systems ... Technology and Devices Int'l ... TechTol Imaging ... TELA Bio ..... Telecardia ... TeleContinuity ... Telefactor ..... Telemedicine Up Close operates as DxUpClose ...... Telik ... Tempest Therapeutics ..... Templex Technology... Tempus ..... Tenax Therapeutics .... Tenaya Therapeutics ..... Tendril ... Tendyne Holdings ..... Tensha Therapeutics ... Tepha ... TeraDiode .... TeraDiscoveries (now Cloud Pharma) .... Terapio ... TeraStor ... Terrabon ... Terrajoule ... TerraMetrics ... Terumo BCT .... Terus Technologies .... TESARO .... TeselaGen Biotechnology .... Tessera Technologies ... Tethys BioScience .... Tetra Discovery Partners .... Tetragenetics ... TetraLogic Pharmaceuticals ... Tetraphase Pharmaceuticals ... TetraVue ... Tezzaron Semiconductor .... TFF Pharmaceuticals .... TGS Knee Innovations ... TG Therapeutics .... Thar Pharma .... Thalchemy ..... The ExOne .... The Medicines ..... Therabron Therapeutics ..... Theraclone Sciences ... Theragenics .... Therametric Technologies ... Theranos .... Therion Biologics ... Thermacore ... Thermage ... Thermal Gradiant .... Thermal Spray Technologies .... ThermalTherapeutic Systems ... Thermedical ... ThermoAura .... ThermoCeramiX .... ThermoGenesis .... Thermon ... TherOx .... Thesan Pharmaceuticals .... Theseus... Thetis Pharmaceuticals ... ThingMagic... Third Wave Technologies .. Thoratech Tech ... Thorley Industries .... ThreeRivers 3D ..... Threshold Pharmaceuticals .... Thrive Earlier Detection ..... ThromboVision .... Thyritope Biosciences .... Tiax ... Tibbetts Industries ... Tibion ..... Tiburio Therapeutics ..... Tilera ... Tillges Technologies ... Tilos Therapeutics .... Tioma Therapeutics ..... TissueGene ..... TissueLink ... Tissue Regeneration Systems .... Titan Pharmaceuticals .... Titan Spine ..... TJ Technologies .... TLC Precision Wafer ... Tmunity Therapeutics .... Tobira Therapeutics .... Tocagen ... Tokai Pharmaceuticals .... Tolerx .... TomoTherapy ... Tone Tree ..... Topia Technology .... TopicalRemedy .... Topokine Therapeutics .... Torax Medical ... Torque Therapeutics ..... Total Immersion ... TotipotentRx .... Totus Solutions .... Toyon Research ..... TP Therapeutics ..... Trace Genomics ..... Tracon Pharmaceuticals ... TranS1 .... TransAstra .... Transatomic Power .... Transcend Medical ...Transcept Pharmaceuticals .... TransCorp ..... Transcriptic ..... TransEnterix ... Transgenomic ... Translattice ..... TransMedics ... Transmeta ... TransMolecular ... Transphorm ..... TransTech .... TransTech Pharma (now vTv Therapeutics) ... Transzyme Transzyme Pharma ... Traverse Biosciences ... Traycer Diagnostic Systems ..... Trellis Bioscience ... Trellis Earth Products ... Trethera .... Trevena ... Trevi Therapeutics ..... Trex Enterprises ... Triad Semiconductor .... Tri Alpha Energy ..... Triangle BioSystems .... Tribogenics .... Tribologix .... Trice Medical .... Trice Orthopedics .... Tricida ..... Trident Systems ... Trilumina .... Trimble Navigation .... Trimeris ... Triquint Semiconductor ... Triton Systems ... Trius Therapeutics ... TriVascular Technologies .... Trovagene ..... Trubion Pharmaceuticals ... Tru-D SmartUVC ..... True Diagnostics .... True Health Diagnostics .... True North Therapeutics .... Truestone ..... TruTouch Technologies ..... Try Eco ..... Tryton Medical ... Tularik .... Turtle Mountain Communications .... TVA Medical ... Tvardi Therapeutics .... Twelve .... Twentyeight-Seven Therapeutics ...... Twin Star Medical ... Twist Bioscience ..... TwoXAR ..... Tyme Technologies .... TypeZero Technologies .... Tyrosine Pharmaceuticals .... Tyrx

uBiome .... UCAN ... UES ... Ulthera .... UltraCell ... Ultragenyx .... Ultralife Batteries ... Ultramet... Ultradian Diagnostics ..... Ultraviolet Sciences ... Unbounded Robotics .... Unchained Labs .... UNIAX ... Unica ... Unidym ... UniEnergy Technologies ..... Unified Nexsys .... Unilife ..... Uni-Pixel .... Uniqure .... United Devices ... United Therapeutics ... United Therapies ..... Unity Biotechnology .... Universal Cells ...... Universal Display ... Universal Robots ..... Universal Technical Resources .... Universal Technology .... Unleash Immuno Oncolytics ..... Unum Therapeutics .... Unwired Nation ... Uptake Medical ... UQM Technologies ... Urbix Resources .... Urigen Pharmaceuticals .... UroGene Pharma ..... US Nanocorp ... Uroplasty ..... US Bioscience ..... US Silicones ... UTC Power .... Utilidata ... Utron ..... UVision360

Vaccinex ..... Vaccinogen .... Vader Systems ..... VakSea .... Vala Sciences ....Valencell ... Valence Technology .... Validity Sensors ... Valmont Industries .... Vanda Pharmaceuticals ... Vanguard Space Technologies ..... Vapogenix ..... Variant Pharmaceuticals ..... Vascudyne ..... Vascular Biogenics (also VBL Therapeutics) ..... Vascular Designs ... Vascular Genesis ..... Vascular Pathways ... Vascular Pharmaceuticals .... Vascular Solutions ..... Vasculox .... VasoGenix Pharmaceuticals ... Vasoptic Medical ..... Vast Therapeutics .... Vativ Technologies ... Vaxart ... Vaxess Technologies .... VaxGen ... VaxInnate ... vCalc .... Vecna Tech ... Vectorlogics .... Vedanta Biosciences .... Veeva Systems .... Veezyon ... VeinAid ... Velano Vascular .... Velicept Therapeutic ..... Velocimed ... Velomedix ... VelosBio ..... VenatoRx Pharmaceuticals ..... Venaxis ..... Vendormate .... Veniti ... Vensun Pharmaceuticals .... VentiRx ... Ventria Bioscience ... Ventrix ..... Ventrus Biosciences ... Veracode ... Veracyte ... Veran Medical Technologies ..... Verastem ... VeraSun Energy ... VerAvanti .... Verax Biomedical ... Verdezyne ... Vergent Bioscience ..... VerinataHealth ... Verenium ... Vericel (formerly Aastrom Bio) .... Verifica-BG ... Veritas Genetics ..... Vermillion .... Vermont Composites ...Veros Systems ... Verrica Pharmaceuticals .... Versar .... Versartis ... Vestagen Technical Textiles .... Vestaron .... VerteCore ..... VerteraSpine ..... Vertex Pharmaceuticals ... VeruTEK Technologies ... Verve Therapeutic .... Vesper Medical ..... Vextec ... VGBioCogCubed .... V-Glass .... VGo Communications ... VGX Pharmaceuticals ..... ViaCell ... ViaCyte .... Viacor .... Viamet Pharmaceuticals ... ViaSat ... Via Separations .... Vical . .. Vicarious .... Vicus Technologies .... Vidacare ... View ..... Vigene Biosciences .... Viking Therapeutics .... Vion Pharmaceuticals ... ViraCor Laboratories ... Viracta Therapeutics ..... Viral Genetics .... Virdante Pharmaceuticals ... Virdia .... Virent Energy Systems ... Viresco Energy ... Virobay .... ViroPharma . .. ViroXis ... Virtify . VirtualScopics .... Virtusa ... Viscardia ..... VisEn Medical ... VisiGen Biotechnologies ... VisionGate ..... VisionQuest ..... Vision-Sciences ... Vistagen Therapeutics ... Vistec Lithography ... Visterra ... Visualase .... Vitae Pharmaceuticals ..... VitalMedix ... Vital Therapies ...... Vital Vio .... VitaPath Genetics ... Vitriflex .... Vium ..... Vivex Biomedical .... Vividion Therapeutics ..... Vivisimo .... Vixar ... Vixel ... Vixiar Medical ..... Vizzario .... Vlingo ... VLST ..... VMware ... Voci Technologies .... Volcano .... VoltServer ... VORAGO Technologies (previously Silicon Space Technology) ..... Vorbeck Materials ... Vor BioPharma ..... Vortex Biosciences ..... Vortex Medical ... Voxel .. voxeljet ..... Voyager Therapeutics .... Vtesse .... VT Silicon .... vTv Therapeutics (formerly TransTech Pharma) ..... VUV Analytics .... Vuzix .... Vyriad .... Vyrx Pharmaceuticals ..... VytronUS

WaferGen Biosystems ... Wakonda Technologies ... Walker Magnetics Group ... Waste2Watergy .... Waveband ..... Wave Computing ..... Waveguide ..... WaveRx ... Weinberg Medical Physics .... WellStat Therapeutics .... Whole Biome ..... Whole Trees ..... WiBotic .... Wicab ..... WildcatDiscovery .... Wiliot ..... Willow Garage ... Wilocity .... Wilson Greatbatch .. Wilson Tool International .... Wilson Wolf Manufacturing ... WiMax.com ... Windlift ... Windtree Therapeutics ..... WinSanTor .... Wintegra ... WISErg .... Wizbe Innovations ... WMR Biomedical (now Arsenal Medical) ... Wolf Technical Services ... WoundZoom .... Woven Orthopedic Technologies .... Wright Materials Research ... Wright Therapy Products ..... W Solar Group

X4 Pharmaceuticals ..... Xanofi ... Xanthus Pharmaceuticals ... XBiotech USA ..... X-Body Biosciences ... Xcede Technologies ..... XCELL BIOLOGIX ..... Xcell Biosciences .... Xcellerex ... XChanger Companies .... Xencor .... X-energy ..... Xenetic Biosciences .... Xenex Disinfection Services .... Xenex Healthcare Services ... XenoGen Biosystems .... Xenomics ... Xenoport ... Xeris Pharmaceuticals ... Xetrios Therapeutics .... XF Technologies .... xG Technology .... Xidex ... Xitronix ... XL Hybrids ... Xlumena .... Xoc Pharmaceuticals ..... Xollai ... Xolve (formerly Graphene Solutions) ... Xoma ... XProSciences (now Icagen) ..... X-Ray Optical .... X-Spine .... XSunX ... Xtalic .. Xtant Medical Holdings ..... Xtent ...Xtreme Power ... XTuit Pharmaceuticals .... Xunlight .... XyloCor Therapeutics .... Xynomic Pharma

Yan Engines ... Yardney Technical Products .... Y-Carbon ... Yulex .... Yumanity Therapeutics .... Yurie

Z ... Zacharon Pharmaceuticals .... ZafGen .... Zavante Therapeutics ..... ZBB Energy ... ZeaChem ... ZeaKal .... Zebra Imaging .... Zebra Medical Vision (Israel) ..... Ze-gen ... ZenBio ... Zenomics .... Zenverge ..... Zeo .... Zephyr Technology ... ZeptoMetrix .... ZeroFOX .... Zero Locus .... Zero Mass Water .... ZetaRx Biosciences .... Zeteo Tech .... Zilker Labs ... Zinc Matrix Power ... Zintera ..... Ziopharm Oncology ... Ziptronix .... Zogenix ... Zosano Pharma ... ZPower ... ZS Genetics ..... zSpace ..... ZS Pharma ... ZSX Medical .... Zumobi ... Zunum Aero ..... Zurex Pharma ... Zwitter Technology .... Zyga Technology .... Zygo ... Zymergen ..... ZymoGenetics ... Zynerba Pharmaceuticals .....Zymeworks ..... Zyomyx ... Zystor Therapeutics ... Zyvex Technologies

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