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Carl Nelson Consulting

phone/ fax 202-331-9757carl@carl-nelson.com SBIR for high tech innovators

Hark,What News?

news and views for entrepreneurs .....as of Aug 14, 2018

Note: Carl Nelson Consulting, Inc is not an investment adviser and may hold a financial interest or client relationship in companies discussed. Looking for older stories? Visit the archives

Xenetic Bio up 28% [Aug 13, 18]

Idera Pharma up 18% [Aug 13, 18]

Arsanis down 19% [Aug 13, 18] reported financial results

Innovate BioPharma down 14% [Aug 13, 18]

XOMA down 12% [Aug 13, 18]

Cerecor (Baltimore, MD; $1.3M SBIR) down 12% [Aug 13, 18]

Galectin Thera down 10% [Aug 13, 18]

Gemphire Therapeutics is halting its phase 2a trial in pediatric nonalcoholic fatty liver disease (NAFLD) because some patients’ disease got worse. [Amirah Al Idrus, Fierce Biotech, Aug 13,18]

ColdQuanta (Boulder, CO; $9M SBIR, founded 2007) raises $6.75M to make it easier to spin up a limited use-case quantum computer [Matthew Lynley, TechCrunch, Jul 25, 18]

Emergent BioSolutions announced it has entered into an agreement to acquire PaxVax (Redwood City, CA; $7M SBIR, founded 2009), focused on specialty vaccines that protect against existing and emerging infectious diseases, for a $270 million [cash]. [Emergent press release, Aug 13, 18] total fundung $200+M [crunchbase.com]

Boston Scientific announced it has signed an agreement to acquire VENITI (Fremont, CA; no SBIR, founded 2010) which has developed and commercialized the VICI VENOUS STENT® System for treating venous obstructive disease. Boston Scientific has been an investor in VENITI since 2016 and currently owns 25 percent of the company [Boston press release, Aug 13, 18] total fundung $65M [crunchbase.com]

Paragon Bioservices (Baltimore, MD; no SBIR) has raised $5M in a funding round disclosed last week in SEC filings. The company, which develops and manufactures biopharmaceuticals, previously had hauled in $15M in a Series A round [DCInno, Aug 13, 18]

biotech Apexigen (San Carlos, CA; no SBIR, founded 2010) announced the successful completion of its Series B and Series C financings in which it raised a total of $73 million. [company press release, Aug 8, 18] advancing a pipeline of novel product candidates with the potential to address life-threatening and difficult to treat diseases [with] total funding $93M [crunchbase.com]

The U.S. Army has been granted emergency approval by [FDA] to use a new type of freeze-dried plasma on the battlefield. The plasma comes in durable plastic bags, is more portable and less susceptible to damage than the current glass bottle system, as well as easier to reconstitute for medical use. [AUSA, Aug 10, 18]

Universal Display up 14% [Aug 10, 18]

Omeros down 18% [Aug 10, 18]

ViaSat down 14% [Aug 10, 18]

Idera Pharma down 15% [Aug 10, 18]

Synaptics down 11% [Aug 10, 18]

Innovate Biopharma down 11% [Aug 10, 18]

Ambys Medicines (Redwood City, CA; no SBIR) started up with a $60 million Series A and an unusual, broad alliance with Japanese pharma Takeda to develop an array of drugs for liver diseases. [Ben Fidler, Aug 9, 18]

bluebird bio and Regeneron Pharmaceuticals (no SBIR) announced a collaboration to apply their respective technology platforms to the discovery, development and commercialization of novel immune cell therapies for cancer. The collaborators will specifically leverage Regeneron’s VelociSuite®platform technologies for the discovery and characterization of fully human antibodies, as well as T cell receptors (TCRs) directed against tumor-specific proteins and peptides, and bluebird bio will contribute its field-leading expertise in gene transfer and cell therapy. [joint companies press release, Aug 6, 18]

The FDA has just approved Alnylam (one SBIR)’s patisiran (Onpattro), making it the first medicine specifically cleared to treat a rare and deadly disease called hereditary transthyretin amyloidosis (hATTR). The decision is a scientific milestone too: it marks the first-ever approval for a medicine that uses RNA interference (RNAi), a method cells can use to silence a gene before it makes a harmful protein. [xconomy.com, Aug 10, 18]

SQZ Biotechnologies (Watertown, MA; no SBIR) a cell therapy company developing novel treatments for multiple therapeutic areas , announced the completion of an oversubscribed $72 million Series C financing. [company press release, Aug 8, 18]

Akouos (Brookline, MA; $200K SBIR) raised $50 million in a Series A financing round to support work on a gene therapy for hearing loss that it hopes to advance into human testing within three years. [company press release, Aug 8, 18]

Amicus Therapeutics (Cranbury, NJ; no SBIR, IPO 2007) announced that [FDA] has granted accelerated approval of Galafold™ (migalastat) 123 mg capsules. Galafold is an oral, precision medicine for the treatment of adults with a confirmed diagnosis of Fabry disease and an amenable galactosidase alpha gene (GLA) variant based on in vitro assay data. [company press reease, Aug 10, 18]

Sarepta Therapeutics announced that it has made a strategic investment and entered into a license and option agreement with Lacerta Therapeutics (Alachua, FL; no SBIR), a gene therapy company using a constellation of proprietary adeno-associated virus (AAV) vector technologies to develop CNS-targeted treatments and lysosomal storage diseases. Sarepta expects to benefit from Lacerta’s expertise in AAV-based CNS-targeted gene therapies, will gain access to Lacerta’s capsid screening and proprietary OneBac manufacturing platform and process for the licensed products, and bolsters its pipeline to 11 gene therapy programs, with three CNS-focused programs from Lacerta. [Sarepta press release, Aug 6, 18]

Struggling women’s fertility company Ovascience (foundd 2013), which trades at less than $1 a share, will [reverse] merge [with $30M] with Millendo Therapeutics (Ann Arbor, MI; no SBIR). The combined company will be 80 percent owned by Millendo shareholders and focus on drugs for rare endocrine disorders. [Ben Fidler, Aug 10, 18]

Athenex announced that both Phase 3 studies, KX-AK-003 and KX-AK-004, had achieved their primary endpoint of 100% clearance of actinic keratosis (AK) lesions at Day 57 within the face or scalp treatment areas, with each study achieving statistical significance (p<0.0001). Statistical significance (p<0.001) was achieved for both face and scalp subgroups as well. [company press release, Jul 26, 18]

The FDA OK’d the cystic fibrosis medicine ivacaftor/lumacaftor (Orkambi), from Vertex Pharmaceuticals for the estimated 1,300 children between two and five years old who have the most common form of the disease. The drug is already approved for adults. [Ben Fidler, Aug 9, 18]

Ampio Pharmaceuticals shares plunged 78 percent after the company disclosed that the FDA wants it to run another trial of its osteoarthritis drug Ampion before filing for U.S. approval. [Ben Fidler, Aug 9, 18]

Houston NASA meetup. NASA is hosting a pitch night Aug. 27 for innovations in artificial intelligence, autonomous robots, and biotech, among other sectors. The Houston event is part of NASA’s Ignite the Night series in which the space agency is soliciting innovation ideas from startups. Another pitch event will be held Aug. 20 in Denver. Applications to pitch in Houston must be received by Aug. 17. [Angela Shah, xconomy.com, Aug 10, 18]

The reality is that, well before Trump became president, global trade imbalances were shrinking. Figures from the [IMF] show that, as a share of the [GDP], the U.S. current account deficit hit a recent peak of 5.8 percent in 2006 and dropped to 2.4 percent by 2017. ... The implications are unexpected. Even according to Trump’s twisted view of trade, much of the needed adjustments have already occurred. [Robert Samuelson, WashPo, Aug 12, 18] Trump's schemes and political appeal rely on a simplistic and emotionally appealing take on cherry-picked economic facts. Caveat emptor: Buy him at your peril.

Idera Pharma up 27% [Aug 9, 18]

TapImmune up 13% [Aug 9, 18]

BioCryst Pharmaceuticals up 13% [Aug 9, 18]

Sangamo Thera up 11% [Aug 9, 18]

Vuzix up 10% [Aug 9, 18]

Liquida Tech up 10% [Aug 9, 18]

Portola Pharma down 18% [Aug 9, 18] reported a net loss of $106M

Gevo down 18% [Aug 9, 18]

The Mayo Clinic acquired an 10.9% stake in epilepsy treatment neuromod startup NeuroOne (Eden Prairie, MN; no SBIR, founded 2009)’s parent firm, according an SEC filing.... is developing a “thin film” electrode technology, originally from the University of Wisconsin, designed to be implanted in the brain. The film can detect irregular brain activity, accurate to single neurons, to pinpoint the source of seizures and tremors, according to the filing, and has been used in testing at the Mayo Clinic. [Fink Densford, massdevice.com, Aug 7, 18]

A pair of biotech start-ups spun off from University of Minnesota research and the state’s first “public benefit corporation” each have landed key taxpayer-funded grants ... The awards to MNPHARM SBC (no SBIR), Miromatrix Medical (Eden Prairie, MN, $600K SBIR) and Superior Organoid Technologies LLC (St. Paul, MN; no SBIR) —each of roughly $100,000—came from Regenerative Medicine Minnesota (RMM), a publicly-funded initiative established in 2014 with a $43.6 million allocation over a 10-year span. [Don Jacobson, Twin Cities Business, Jul 12, 18] Miromatrix raised $6M in July.

the head of Navy acquisition has stood up a task force to ensure emerging technology makes it into the service's new weapons. [Defense One's Global Business Brief, Aug 8, 18] Every service often talks of innovation but tends to bury it in unavoidable problems with logistics and dogma, until ships or planes start being disabled or killed. If you have proprietary ideas for countering the small-ship Iranian Navy, by all means dial up the Navy.

Don't expect procurement innovation. fewer than half [of government acquisition professionals] rate innovation as important to successful acquisitions. Only oversight rated lower in importance among acquisition professionals, and Chvotkin said it may be because feds are confused about what innovation actually means. [Frank Konkel, NextGov, Jul 19, 18] Government procurement is, after all, protected by a mass of regulation to prevent dumb or corrupt dealing.

The Chinese theft of U.S. intellectual property remains a “critical” threat, with perpetrators who have adapted to evade the structures of a 3-year-old ban on such hacking, according to a top-secret report intelligence officials sent to Congress ... “Most Chinese cyber operations against U.S. private industry that have been detected are focused on cleared defense contractors or IT and communications firms whose products and services support government and private sector networks worldwide,” it reads. One such product, the report says, is CCleaner, a popular consumer application that removes unwanted files from computers. [Patrick Tucker, NextGov, Jul 27, 18]

Collateral Damage. A container ship carrying a $20 million worth of soybeans [70,000-tonnes] has been circling off the Chinese coast for over a month after being caught in the middle of [Trump's] US-China trade war. [Yahoo Finance, Aug 8, 18]

Outrageous.The President of permanent outrage and insult renewed his attacks on NFL players who protest during the national anthem, claiming they “wanted to show their ‘outrage’ at something that most of them are unable to define.” [The Hill, Aug 10, 18] Autocrats hate competition.

Innovative Biopharma up 24% [Aug 8, 18]

Ra Pharma up 11% [Aug 8, 18]

Applied Optoelectronics up 10% [Aug 8, 18]

XOMA down 21% [Aug 8, 18] reported earnings

FDA rejects Pain Therapeutics' lead drug, Company makes major pivot away from painkillers to Alzheimer's [Austin Business Journal, Aug 8, 18]

BioCryst Pharmaceuticals announced the completion of a public offering with gross proceeds of $57M .... [also] announced that the Company has been granted [FDA] Fast Track Designation for BCX7353 for the prevention of angioedema attacks in patients with hereditary angioedema (HAE). [company press releases, Aug 6, 18]

Constitutional liberties be gone. Forty-three percent of Republicans surveyed in a new Ipsos poll said Trump should have the authority to shut down the news media. Almost a third of Americans (29 percent) say “the news media [are] the enemy of the people,” offering support for a false statement often voiced by the president as his opinion [The Hill, Aug 8, 18] Political power from baldfaced lies. What do these people expect from a dictatorship with government control of the news? A reborn enlightened despot from the Middle Ages?

Akcea Thera up 14% [Aug 7, 18]

II-VI up 13% [Aug 7, 18]

Arsanis up 11% [Aug 7, 18]

CryoLife up 10% [Aug 7, 18]

Gemphire Thera (Livonia, MI; no SBIR) down 51% [Aug 7, 18] announced that [FDA] requested that the Company produce data from a sub-chronic toxicology study to provide information to support lifting the partial clinical hold on gemcabene with respect to clinical trials of longer than six months in duration. [company press release, Aug 6, 18]

Luminex down 28% [Aug 7, 18] announced financial results for the second quarter

Spark Thera down 28% [Aug 7, 18] announced financial results for the quarter

TransEnterix down 12% [Aug 7, 18]

Alnylam Pharma is moving forward with plans to double its office and manufacturing space, as well as its staff, by 2020. The FDA will decide on the company's first drug this week. [Allison DeAngelis, Boston Business Journal, Aug 7, 18]

Aziyo Biologics (Silver Spring, MD; no SBIR) raised $10M from seven investors in a funding round ... focuses on regenerative medicine in cardiology, orthopedics and wound care. .. nearly doubling its funding total ... products are used mostly as implants for surgical procedures. [DCInno, Aug 7, 18]

Paratek Pharma up 12% [Aug 6, 18]

Geron up 10% [Aug 6, 18]

Surmodics up 10% [Aug 6, 18]

Zynerba Pharma up 10% [Aug 6, 18]

Translate Bio down 12% [Aug 6, 18]

Regeneron Pharmaceuticals [develops antibody drugs] and Bluebird Bio [gene and cell therapy specialist] have struck a wide-ranging partnership to broaden the reach of their respective cancer immunotherapy work, inking a deal to develop multiple cell therapies together. [Ben Fidler, xconomy.com, Aug 6, 18]

With little surprise, Pain Therapeutics has been hit with a complete response letter from the FDA for Remoxy ER, its extended-release, capsule gel form of the opioid oxycodone. .... According to FDA: “The data submitted in [the] NDA do not support the conclusion that the benefits of [REMOXY] Extended-Release Capsules outweigh the risks,” the company said in a brief update. [Ben Adams, Fierce Biotech, Aug 6, 18]

NewLink Genetics has cut its headcount by a third to buy the time it needs to prove that—despite setbacks—its IDO inhibitor indoximod is still worth pursuing. [Phil Taylor, Fierce Biotech, Aug 1, 18]

Cree accuses employee of stealing secrets worth more than $100 million [Raleigh News & Observer, Aug 6, 18] Hold the pity! An ugly reminder that North Carolina's economic success derives from the textile industry that moved from New England for the cheap ununionized labor. New England's textile industry, in turn, was born from machine designs stolen from England's Industrial Revolution makers. Economics knows no morals.

American companies [particularly Apple] are borrowing money to buy their own shares in what is tantamount to a huge, slow-motion leveraged buyout. ... In some cases, they have done so simply to push up share prices so that management can meet goals for quarterly earnings or metrics that trigger compensation. [Mihir A. Desai, New York Times, Aug 6, 18]

American companies [are also testing government's management abiity] in that they have filed thousands of tariff-exclusion requests since the tariffs on steel and aluminum began this spring. [Jeff Sparshott, Wall Street Journal, Aug 6, 18] How does a caustically shrinking government judge winners and losers in industrial policy? Politics always sounds better than it actually works.

There hasn’t been [a trade war] since the 1930s. That ended so badly the participants created a world trade body to mediate disputes. ... No longer. With the U.S. and China threatening to put tariffs on virtually all the other’s trade and neither side pushing for a new global trade round, “trade war” is becoming the appropriate description. [Bob Davis, Wall Street Journal, Aug 6, 18]

Millions of words have been spilled on covering Chinese history, culture, demographics, and politics will matter over the course of the next 20 years or so, but beyond that, only one thing will matter:Will the Chinese have the world’s best AI? If they do, then they will take over the world if they feel like it. If they do not, then they won’t. [Kevin Drum, Foreign Affairs, J/A18] Will it take an Act of Congress to restore sanity to US international trade?

Energous up 13% [Aug 3, 18]

Immersion down 24% [Aug 3, 18] reported earnings

Idera Pharma down 11% [Aug 3, 18]

Immunomic Therapeutics (Rockville, MD; $600K SBIR, founded 2005) raised $315K in a funding round in SEC filings. The clinical-stage biotech company studies nucleic acid immunotherapy platforms. It has previously raised more than $14M. [Kieran McQuilkin, DCInno, Aug 3, 18]

Please, please, buy our stuff. [SECSTATE] promised a new era of U.S. economic engagement with Southeast Asian countries, extending an olive branch to a region increasingly concerned about a U.S.-China trade fight. [Wall Street Journal, Aug 3, 18] Please also, ignore our manners.

Fisher Ames, a representative from Massachusetts in the first U.S. Congress, once compared autocracy to a merchant ship, “which sails well, but will sometimes strike on a rock, and go to the bottom.” A republic, he said, “is a raft, which would never sink, but then your feet are always in water.” [Daniel Deudney and GJ Eikenberry, Foreign Affairs, J/A18]

DexCom up 31% [Aug 2, 18] "Q2 was a fantastic quarter for DexCom and demonstrates that CGM adoption is increasing significantly," said Kevin Sayer, DexCom's President and CEO. [company press release, Aug 1, 18]

Akcea Thera up 10% [Aug 2, 18]

Epizyme down 24% [Aug 2, 18] reported quarterly results

Marinus Pharma down 13% [Aug 2, 18]

Exact Sciences down 13% [Aug 2, 18]

Ra Pharma down 13% [Aug 2, 18]

Zynerba Pharma down 11% [Aug 2, 18]

SBIR was made permanent for the Defense Department continuing beyond the present expiration date in 2022 by Section 893 of the NDAA2019. Politics at work.

Luna Innovations up 16% [Aug 1, 18]

Neurocrine Biosciences up 13% [Aug 1, 18]

Ameican Superconductor up 12% [Aug 1, 18]

TapImmune up 11% [Aug 1, 18]

NewLink Genetics down 16% [Aug 1, 18]

resTORbio down 14% [Aug 1, 18]

Coap Tech (Baltimore, MD; one SBIR) raises $2.35 million [seed round], moves toward FDA clearance.... developed a technology that allows for more efficient, less-invasive feeding tube placement in hospital patients. [Morgan Eichensehr, Baltimore Business Journal, Jul 24, 18]

Raydiant Oximetry (Sacramento, CA; no SBIR, founded 2016), winner of last year’s startup business competition at UC Davis, has raised a $1 million seed round and secured over $200,000 from [NIH] [ Olivia Rockeman, Sacramento Business Journal, Jul 30, 18] ] developed a better fetal monitor to improve outcomes for mothers and babies during childbirth. [company website]

Illumina up 12% [Jul 31, 18]

nLight down 17% [Jul 31, 18]

Idera Pharma down 13% [Jul 31, 18]

Translate Bio down 10% [Jul 31, 18]

Osram (Germany) has added to its expertise in semiconductor-based optical security technology by acquiring Vixar (Plymouth, MN; $1.4M SBIR, founded 2005 by two former Honeywell engineers). Already a technology leader in infrared LEDs and infrared laser diodes, Osram will have a unique breadth of technological expertise and an expanded product portfolio after bringing on board Vixar’s specialist capabilities in the field of VCSEL [Osram press release, May 3, 18] total Vixar funding $2.5M [crunchbase.com]

Sienna Biopharmaceuticals’ (Westlake Village, CA; no SBIR, founded 2010) acne candidate SNA-001 has comprehensively failed two phase 3 trials. The addition of the silver particle treatment to laser light therapy failed to improve outcomes against three key endpoints, [Fierce Biotech, Jul 30, 18] total funding $86M [crunchbase.com]

Qualcomm to Buy Back $10 Billion of Its Shares [Wall Street Jurnal, Jul 31, 18]

ARCA Biopharma (Westminister, CO; no SBIR, founded 1992) applying a precision medicine approach to developing genetically-targeted therapies for cardiovascular diseases, announced that it has received [FDA] guidance following an End-of-Phase 2 meeting regarding the Phase 3 program for ARCA’s pharmacologically unique beta-blocker Gencaro as a potential genetically-targeted treatment for atrial fibrillation (AF) patients with heart failure (HF). [company press release, July 31, 2018] total funding $90M [crunchbase.com]

More industrial policy. The Trump administration embraced an emerging corner of the financial sector, telling companies that offer new ways to bank and invest that the federal government wants to help them grow. [Wall Street Journal, Aug 1, 18] Standard free market Republicans would be aghast at such a proposition. But they quiver at the thought of opposing Trump's blindly loyal base.

If them, then us, too. Jane Hardy, the chief executive of a company [Brinly-Hardy, southern Indiana] that makes lawn-care equipment, says she had to lay off 75 employees this summer because of President Trump’s trade war. .... The U.S. Chamber of Commerce estimated the total price tag could hit $39 billion if Trump compensated the losses across all industries [and] called it a “slippery slope” for Trump to determine who gets help and who doesn’t. [Recall the Republican horror for "industrial policy."] [Heather Long, WashPo, Jul 30, 18]

Innovate Biopharma down 20% [Jul 30, 18]

Aduro Biotech down 10% [Jul 30, 18]

The U.S. Navy has awarded 23 companies [of 28 offers] positions on a potential five-year, $794.5 million contract to support the development and fabrication of unmanned undersea vehicles. [Jane Edwards, GovConWire, Jul 30, 18] Rite Solutions (Middletown, RI; $8.2M SBIR, incl one at $3.6M) only SBIR awardee.

Governor Northam announced that Aurora Flight Sciences (lots of SBIR, now a Boeing company), a pioneer in unmanned aircraft and autonomous flight, will invest more than $13.75 million to expand its operation in Manassas [twice a Civil War battlefield] [Virginia state press release, Jul 26, 18].

Ceres Nanosciences (Manassas, VA; $2.2M SBIR) announced it is has received [FDA] Breakthrough Device designation for its new point-of-care Nanotrap® Lyme Antigen Test System. ...requiring only a patient’s urine sample [company press release, Jul 12, 18]

Fine words today. Secretary of State Mike Pompeo said in a speech that the U.S. was committed to growing trade and investment in Asia, and he assured potential strategic and trade partners the U.S. wants partnership, not domination. [Wall Street Jurnal, Jul 30, 18] How will the POTUS step on that message tomorrow with more America Alaone threats?

Master mercurial ingrate Trump lashed out at the powerful public policy and political network built by billionaires Charles and David Koch after it criticized his leadership and broke with its tradition of backing Republican candidates by declining to support [one of] the party’s pick ... “The globalist Koch Brothers, who have become a total joke in real Republican circles, are against Strong Borders and Powerful Trade," Trump tweeted Tuesday. "I never sought their support because I don’t need their money or bad ideas.” [John McCormick, Terrence Dopp, Bloomberg, July 31, 18] And who got the Trumpophile Congress elected?

resTORbio up 13% [Jul 27, 18]

Genprex down 55% [Jul 27, 18]

Xenetic Biosci down 13% [Jul 27, 18]

Apple breaks up with Qualcomm: Will Intel chips mean slower iPhones? - Apple's break from Qualcomm, however, may mean slower iPhones compared to its Android counterparts, as phones using Qualcomm chips outperformed phones using its competitors' chips, according to a recent study. [San Jose Mercury News, Jul 27, 18]

Medical startup Kypha (St Louis, MO; $500K SBIR, founded 2009) raised another $950K [Brian Robbins, St Louis Business Journal, Jul 27, 18] total funding $15M [crunchbase.com]

“The rate of profit...is always highest in the countries which are going fastest to ruin,” [Smith] argued. America’s corporate-profit rate is currently at historical highs. Had regulators read more Smith, the American economy might be in better shape. [The Economist reviewing Jesse Norman's biography of Adam Smith, [Jul 28, 18]

The chaos surrounding the mammoth [immigrant family] reunification task, which had little precedent and no single playbook, shows what happens on the ground when an administration makes or reverses policy on the fly. [ Nour Malas and Alicia A. Caldwell, Wall Street Journal, Jul 27, 18] When a President's only management tool is an off-hours Twitter, and the people who claim to be guardians of religious morality support an amoral President.

Congress and President Trump Are Spending Money and Cutting Taxes Like There Is No Tomorrow. [Howard Gleckman, taxpolicycenter.org, Jul 28, 18] Serving a banquet with borrowed money with no plan for re-payment. Not a fresh idea: W had the same ideas.

Superconductor Tech down 40% [Jul 26, 18]

drug maker Liquidia Technologies (Morrisville, NC; one SBIR) raised $50 million in an [IPO] [Raleigh News & Observer, Jul 26, 18]

resTORbio (Boston, MA; no SBIR) nearly doubled based on positive results the company released from a Phase 2b trial of its drug for respiratory tract infections. The drug, RTB101, is a pill that blocks an enzyme called TORC1. The company says the drug works by boosting immune function, along with other benefits. ResTORbio licensed the drug from Novartis last year. [xconomy.com, Jul 26, 18] total funding $65M [crunchbase.com]

Glaxo SmithKline makes $300M investment in 23andMe, forms 50-50 R&D pact [Fierce Biotech, Jul 26, 18]

Sutro Biopharma (South San Francisco, CA; no SBIR) reeled in an $85.4 million series E that will advance some early-stage programs as well as its cancer pipeline, which includes a pair of antibody-drug conjugates (ADCs). [Amirah Al Idrus, Fierce Biotech, Jul 26, 18] Also, Merck paid Sutro Biopharma $60 million to co-develop a group of protein drugs for cancer and autoimmune diseases. [Ben Fidler, xconomy.com, Jul 27, 18]

Biogen has bolted on a couple of early-stage drug candidates for neuromuscular diseases via a $535 million deal with startup AliveGen [Thousand Oaks, CA; no SBIR). [Phil Taylor, Fierce Biotech, Jul 24, 18]

AbbVie in cooperation with Neurocrine Biosciences (San Diego, CA; $11M SBIR, founded 1992) announced that [FDA] approved ORILISSA™ (elagolix), the first and only oral gonadotropin-releasing hormone (GnRH) antagonist specifically developed for women with moderate to severe endometriosis pain.1,2 [joint companies press release, Jul 26, 18]

A phase 1/2a trial Sarepta Pharma’s gene therapy for Duchenne muscular dystrophy (DMD) has been placed on clinical hold by the FDA after rogue DNA was found in a test sample. [Phil Taylor, Fierce Biotech, Jul 26, 18]

Convelo Therapeutics (Cleveland, OH) launched with plans to develop drugs that regenerate myelin, which helps nerve cells send signals and breaks down in multiple sclerosis. Derrick Rossi, a co-founder of Moderna Therapeutics, Intellia Therapeutics, and Magenta Therapeutics, is Convelo’s president and CEO. [Ben Fidler, xconomy.com, Jul 27, 18]

Trees don't grow to the sky. Investors dumped Facebook shares after the company reported a sharp slowdown in sales growth in coming quarters along with rising spending on security and privacy enhancements. ... Before Facebook’s tumble, more than half the returns in the Standard & Poor’s 500-stock index this year had been provided by just a handful of technology-related stocks, said Savita Subramanian, an equity strategist at Bank of America Merrill Lynch. [Matt Phillips, New York Times, Jul 26, 18]

Trump punts. The agreement with the European Union that President Trump announced week would lower tariffs and other trade barriers, reduce bureaucratic roadblocks and end conflicting regulations for drugs and chemicals. The U.S. was pursuing much the same approach under President Barack Obama, through a deal that Mr. Trump shelved last year. [Chris Stanford, New York Times, Jul 26, 18]

Seeking foreign investors? This year, net inward investment into the United States by multinational corporations—both foreign and American—has fallen almost to zero, an early indicator of the damage being done by the Trump administration’s trade conflicts and its arbitrary bullying of companies and governments. [Adam Posen, Foreign Affairs, Jul 26, 18] Welcome to America Alone.

Strategic wasteland. Scott Irwin, an agricultural economist at the University of Illinois, [Politico’s Catherine Boudreau] says that “farmers’ biggest fear is this could put the United States in the category of an unreliable supplier,” which could make it hard to recover lost customers. “We’ve put a lot of time, effort and energy into building markets like China,” said Stuart Woolf, a farmer in California. “We’re constantly trying to build trust with our strategic partners. With this administration, there doesn’t seem to be any strategic partners,” Woolf added. [Yuval Rosenberg and Michael Rainey, Fiscal Times, Jul 27, 18] The likely winner in the soybean tariff war: Brazil.

iRobot up 17% [Jul 25, 18]]

Innovate Biopharma up 13% [Jul 25, 18]

Menlo Thera up 11% [Jul 25, 18]

Anaptys Bio up 11% [Jul 25, 18]

Superconductor Tech down 29% [Jul 25, 18] Announces Pricing of $9 Million Public Offering [company press release, Jul 25, 18]

GlycoMimetics down 10% [Jul 25, 18]

Alector (South San Francisco, CA; $1.5M SBIR, founded 2013) announced that it raised $133 million in a Series E round, and unveiled the first three immune system-modulating antibodies in its pipeline that will be tested in clinical trials. .... expects to move its drug development program into the clinic later this year, fundraising total now adds up to $415 million [Bernadette Tansey, xconomy.com, Jul 25, 18]

Nabriva Therapeutics (Ireland) announced that it has acquired Zavante Therapeutics (San Diego CA; no SBIR, founded 2015), developing novel therapies to improve the outcomes of hospitalized patients, for upfront consideration of approximately 8.2 million shares of Nabriva. In addition, Zavante Therapeutics’ to receive up to $97.5 million upon the achievement of specified regulatory and commercial milestones. [joint Navibra press release, Jul 24, 18] Zavante total fundung $65M [crunchbase.com]

Trade war casualty. China kills Qualcomm's $44 billion deal for NXP,the latest casualty in the escalating US-China trade tensions. QCOM is now stuck with paying NXP a $2 billion breakup fee.... In March, President Donald Trump blocked a $117 billion takeover of Qualcomm by rival Broadcom (AVGO), arguing that it could help China beat the United States in developing 5G technology. The following month, the Trump administration imposed a crippling ban on Chinese smartphone and telecommunications company ZTE, preventing it from buying crucial parts from American companies. [Sherisse Pham, CNN, Jul 26, 18]

Productivity myth. Popular though the stealth productivity boom is, it is a myth. A new study finds that official statistics do tend to understate productivity, but by less than two decades ago. So even if all the benefits of social networks, online shopping and less invasive surgery were being measured, it probably wouldn’t change the overall picture: Productivity growth is historically slow. The study is by the Hutchins Center on Fiscal and Monetary Policy at the Brookings Institution. [Greg Ip, Wall Street Journal, Jul 25, 18]

The Credit Card State. The amount of corporate taxes collected by the federal government has plunged to historically low levels in the first six months of the year, pushing up the federal budget deficit much faster than economists had predicted. [New York Times, Jul 25, 18] Annual deficit to soon reach $1 trillion (that's $1000 billion) after Republican Congress caved to corporations and other wealthy patrons by accepting the fantasy economic projections from the corporatist Treasury Secretary.

Innovate Biopharma up 25% [Jul 24, 18]

Superconductor Tech down 24% [Jul 24, 18] completed a one-for-ten (1:10) reverse split of its common stock [company press release, Jul 24, 18]

Tapimmuneech down 17% [Jul 24, 18]

Syros Pharma down 11% [Jul 24, 18]

Cerapedics (Westminster, CO; no SBIR, founded Y2K), announced that the company completed a $22 million financing [to] to accelerate the commercial release of i-FACTOR™ Peptide Enhanced Bone Graft and support the execution of a second Level I investigational device exemption (IDE) human clinical study that will broaden our market indication in the $2 billion U.S. spinal market,” said [CEO] Glen A. Kashuba. [company press release, Jul 13, 18]

Miromatrix Medical (Eden Prairie, MN; $600K SBIR) announced raising $15.7 million in Series B-2 funding, surpassing its goal of $10 million ... to bioengineer transplantable organs and save lives by eliminating the organ transplant waiting list, as well as the continued commercialization of Miromatrix’ novel acellular products based on perfusion decellularization. [company press release, Jul 12, 18]

Congress settled on a significant cut a number of the Pentagon’s back office functions. [Government Executive, Jul 24, 18] The usual result is less attention to minor programs like SBIR.

Post truth, no trust. The proliferation and Balkanization of news sources, abetted by the cloak of web anonymity, has left people feeling that they “have been denied trustworthy sources of information,” Mr. Blackburn writes. In response, they “take refuge in believing whatever they would like to be true.” If you can’t trust anyone or anything, you are left only trusting your gut. [Julian Baggini reviewing Blackburn's On Truth, Wall Street Journal, Jul 24, 18]

Friendly fire victims. The government announced a $12 billion plan to assist farmers who have been hurt by President Donald Trump’s trade disputes with China and other trading partners. The plan focuses on Midwest soybean producers. [KEN THOMAS and PAUL WISEMAN, AP, Jul 24, 18] Run more deficit spending to recover votes for political trade charades. “This is becoming more and more like a Soviet-type of economy here: Commissars deciding who’s going to be granted waivers, commissars in the administration figuring out how they’re going to sprinkle around benefits,” said Sen. Ron Johnson (R-WI). [Fiscal Times]

Innovate Biopharma down 14% [Jul 23, 18]

Sangamo Biosciences acquired [for €72 million] French biotech TxCell, adding an experimental technology with the potential to treat autoimmune diseases with cell therapy. [Ben Fidler, xconomy.com, Jul 23, 18]

Ceres Nanosciences (Manassas, VA; $2.2M SBIR) received a designation under the FDA’s Breakthrough Device program, which means its Lyme disease test could get to market much faster. The announcement comes soon after a $9M Series A round at the end of May, bringing its total funding to about $15M. [DCInno, Jul 23, 18]

Investors have pushed U.S. small-cap stocks to record highs while seeking a haven from tariff-related tensions, but the popular trade is beginning to appear vulnerable. ... the Russell 2000, an index that tracks shares of smaller companies, up 11% this year, compared with the S&P 500’s 4.8% gain. ... Russell 2000 is trading at a forward price-to-earnings ratio of 22.4 as of Thursday, compared with the S&P 500’s 16.6 [Danielle Chemtob, Wall Street Journal, Jul 23. 18]

The U.S. Army has chosen 10 firms to compete for rapid prototyping orders under a potential three-year, $192 million contract. [GovConWire, Jul 23, 18] Fibertek had 127 SBIR awards; Trideum two awards.

Loved the promises. Trump’s tax cut hasn’t done anything for workers: Wages were supposed to rise. Instead, they’ve fallen, by Noah Smith, Bloomberg opinion contributor. https://trib.al/G69T9at [The Hill, Jul 24, 18]

Allakos up 12% [Jul 20, 18]

Invuity up 11% [Jul 20, 18]

Zynerba Pharma down 24% [Jul 20, 18] announced the pricing of public [to raise] $32.5 million [company press release, Jul 20, 18]

Rubius Therapeutics (Cambridge, MA; no SBIR, founded 2013), a preclinical biotech developing novel therapies based on red blood cells, raised $241 million by [IPO]. [nasdaq.com, Jul 19, 18] creating RCTs™ as a new class of medicines. Leading applications include programs in cancer, enzyme deficiency diseases and the induction of tolerance to treat autoimmune disease. total funding $245M [crunchbase.com]

Johns Hopkins School of Medicine-born biotech startup Neuraly (Germantown, MD; no SBIR, founded 2016) recently raised $36M in Series A financing as it plots trials for its first drug candidate. [DCInno, Jul 19, 18]

Bristol-Myers Squibb and Gritstone Oncology (Emeryville, CA; no SBIR, founded 2015) announced that the companies have entered into a clinical trial collaboration to evaluate the safety and tolerability of Gritstone’s personalized neoantigen immunotherapy, GRANITE-001, which comprises sequential delivery of neoantigens to patients within an adenovirus-based vector (prime) and a self-replicating RNA-based vector (boost), in combination with Bristol-Myers Squibb’s programmed death-1 (PD-1) immune checkpoint inhibitor, Opdivo (nivolumab), and Opdivo plus Yervoy (ipilimumab), in patients with advanced solid tumors. [joint companies press release, Jul 19, 18] total funding $195M [crunchbase.com]

IFM Therapeutics (Cambridge, MA; no SBIR, founded 2015) is hiving off its NLRP3 stable into a subsidiary dubbed IFM Tre. The new unit, which starts out with $31 million in series A funding, expects to bring its lead asset into phase 1 in 2019. [Amirah Al Idru,s Fierce Biotech, Jul 19, 18] total funding $27M [crunchbase.com]

Pliant Therapeutics (South San Francisco, CA; no SBIR, founded 2016) announced that it has raised $62 million in a Series B financing [to] support the initiationand proof - of-concept clinical trials in idiopathic pulmonary fibrosis (IPF) and primary sclerosing cholangitis (PSC), as well as ongoing drug discovery programs targeting other fibrotic diseases. [company press release, Jul 17, 18] total funding $107M [crunchbase.com]

Velicept Therapeutics (Malvern, PA; no SBIR, founded 2015) with potential treatment for overactive bladders raises $15.5M ... lead new drug candidate was originally discovered by GlaxoSmithKline researchers. [John George, Philadelphia Business Journal, Jul 19, 18] total funding $15M [crunchbase.com]

PTC Therapeutics (South Plainfield, NJ; no SBIR) is looking to gene therapy in a bid to broaden its pipeline, scooping up privately held Agilis Biotherapeutics (Cambridge, MA; no SBIR) in a cash and stock deal..... will pay $50 million up front, plus $150 million in PTC shares, for Agilis. Agilis, based in , could get up to $595 million more depending on the progress of its three most advanced gene therapy programs, which target rare central nervous system disorders. [Frank Vinuan, xconomy.com ,Jul 19, 18]

An Army technology competition aimed at small tech firms and entrepreneurs with big game-changing ideas received 340 entries by its July 11 deadline. The Expeditionary Technology Search, xTechSearch, will offer prizes of up to $200,000 for the best technology that addresses an Army mobilization priority. What to watch: The papers are being reviewed by Army scientists and engineers. Notifications will begin today for those who will be invited to make a face-to-face pitch. [ausa.org, Jul 23, 18]

Allakos (San Carlos, CA; no SBIR, founded 2012) up 33% [Jul 19, 18] after IPO raised $130M; boosting a busy period for health care IPOs. [Investors Business Daily, Jul 19, 18] total funding $#4M [crunchbase.com]

Arcadia BioSci up 11% [Jul 19, 18]

Xenetic BioSci up 10% [Jul 19, 18]

Mersana Thera down 32% [Jul 19, 18] a clinical-stage biopharmaceutical company focused on discovering and developing a pipeline of antibody drug conjugates (ADCs) based on its Dolaflexin® and other proprietary platforms, announced that [FDA] placed the Phase 1 study of XMT-1522 on partial clinical hold. [company press release, Jul 19, 18]

xxxx

Crinetics Pharma up 44% [Jul 18, 18] focused on the discovery, development and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors, announced the pricing of its [IPO to raise $102M] [company press release, Jul 17, 18]

AVROBIO up 17% [Jul 18, 18]

Cocrystal Pharma up 13% [Jul 18, 18]

CTI BioPharma down 33% [Jul 18, 18] announced that it recently conducted a Type B meeting with [FDA] for its lead product candidate pacritinib [to] discuss the regulatory pathway for pacritinib. Based on FDA feedback, the Company plans to conduct a randomized Phase 3 study in patients with myelofibrosis. [company press release, Jul 18, 18]

Innovate BioPharma down 12% [Jul 18, 18]

Xenetic BioSci down 10% [Jul 18, 18]

Tetra Discovery Partners (Grand Rapids, MI; $8.7M SBIR), a biotech advanced its Fragile X Syndrome treatment, BPN14770, to Phase 2 clinical trials. (Fragile X Syndrome is the most common genetic form of autism.) The company said in a press release that its small molecule drug, BPN14770, has shown in mouse studies “the ability to improve the quality of connections between neurons and to improve multiple behavioral outcomes.” [Sarah Schmid Stevenson, xconomy.com, Jul 18, 18]

biotech startup Inari Agriculture (Cambridge, MA; no SBIR, founded 2016) is being introduced today with the mission to transform agriculture and its impact on society and the environment by developing a more personalized plant breeding approach. [Cindy Zimmerman, agwired.com, Jul 18, 18]

A new [DARPA] program called SHort-Range Independent Microrobotic Platforms, or SHRIMP, is looking to reward researchers who can overcome the big barrier to micro-robot fielding: creating strong motors that sip power. [DefOne, Jul 18, 18] read Solicitation ; response date Sept 26, 18. DARPA press release. Military permanent need: high performance, low weight and volume, low power demand. Cost - a secondary goal.

Biotech stocks are hot tickets once again on Wall Street and that is bringing a wave of initial public offerings. The risk is the high demand for these companies is offset by a wave of new supply. [Charley Grant, Wall Street Journal, Jul 18, 18]

Back, forth, up, down, for, against, ally, foe. Rolf Mowatt-Larssen, a 25-year CIA officer now at Harvard's Belfer Center, writes at Just Security: "If there is a silver lining in this disastrous trip, surely NATO, as well as leaders in Germany and the United Kingdom, must now realize that they cannot trust what the US President says, appears to do, or promises. This lesson will be useful for our allies in forging a more independent pathway moving forward, until this American nightmare is over." [The D Brief, Jul 18, 18]

Zosano Pharma up 13% [Jul 17, 18]

Biocept (San Diego CA; one SBIR, market cap $16M) down 11% [Jul 17, 18]

Genprex, a clinical-stage biopharmaceutical company working on cancer treatments, raised an additional $10 million. ... Seeking Alpha recently reported on the company’s prospects, ... noting that the company’s Phase II trial has been suspended for more than a year. [Brent Wistrom, Austin Inno, May 31, 2018]

Shattuck Labs (Austin, TX; no SBIR, founded 2016), a biotech that licensed technology from cancer drug developer Heat Biologics, added $46.6M equity round, according to [SEC] securities filing. [David Holley, xconomy.com, May 30, 18] developing a breakthrough platform for immunotherapy [company website]

Kypha (St Louis, MO; $500K SBIR, founded 2009), a biotechnology startup, acquired Biosensia, a medical device firm in Ireland. Terms not disclosed. .... has developed a diagnostic tool that analyzes inflammation. Biosensia has developed a point-of-care diagnosis system that produces laboratory quality quantitative and qualitative results with a disposable cartridge for up to 24 analytes in a multiplex format. [Brian Feldt, St Louis Post Dispatch, Jul 16, 18] total funding $14M [crunchbase.com]

Genetesis (Mason, OH; no SBIR, founded 2013), a medical device company using biomagnetic imaging for ER chest pain triage, raised a $7.5 million Series A [Will Flanagan, WisconsinInno, Jul 6, 18] total funding $9M [crunchbase.com]

Vergent Bioscience (Minneapolis, MN; no SBIR, founded 2014), a biotech startup that aims to make it easier for physicians to see cancerous tissue during surgery, raised $8.7 million to fund clinical trials. ... developing a molecularly-targeted probe that binds to enzymes overexpressed in tumor tissue, activating a brightly fluorescing dye. [company press release., Jun 12, 18] total fundong $9M [crunchbase.com]

DOD has released a memorandum that would authorize contracting officers to use a competitive procedure to procure “innovative” commercial technologies and services as part of four-year pilot program in a move to encourage participation from non-traditional contractors, Federal News Radio reported. DoD’s acquisition officials will release “general solicitations” and competitively pick [fixed-price] proposals based on a peer review conducted by subject matter experts under the “commercial solutions opening” method authorized by the fiscal 2017 National Defense Authorization Act. [Jane Edwards, GovConWire, Jul 17, 18] Keep in minds that military equipment has to be ready to deploy from the Arctic tundra to the rainforest tropical jungle next week.

The world's second biggest private funder of medical research, the London-based charity Wellcome Trust, announced it will provide £250 million [the Wellcome Leap Fund] for unconventional research that could transform science or health. ... earmarked for ideas shut out from traditional funding because they are less likely to succeed, and for projects with researchers who lack a background in the life sciences but bring other expertise. .. first research programs could start in late 2020. [Science, Jul 13, 18]

Oh, those promises. The updated federal budget now includes a projected 2019 deficit of $1.085 trillion — more than double the $526 billion the White House called for in its 2018 budget. “This is a striking acknowledgement following almost two years of claims that economic growth unleashed by these policies will wipe deficits away,” said Maya MacGuineas, president of the Committee for a Responsible Federal Budget. [Fiscal Times, Jul 16, 18] Never mind, the baseless hand-waving helped pass the Aid-for-the-Wealthy tax cuts, a prime Republican [donor] objective for decades. The Gilded Age with the best government money can buy is progressing nicely.

Innovate BioPharma down 66% [Jul 16, 18] apparently spurred by a filing related to a proposed stock offering. Innovate filed a securities registration statement amendment [Motley Fool, Jul 16, 18]

Compass Therapeutics (Cambridge, MA; no SBIR, founded 2014) committed to the ambitious goal of comprehensively drugging the human immune system, today announced the closing of the final $49 million of its $132 million Series A financing [to] advance its next-generation antibody-based therapeutics into the clinic. [company press release, Jul 12, 18] total funding $116M [crunchbase.com]

Nohla Therapeutics (Seattle, WA; no SBIR, founded 2015) a leading developer of universal, off-the-shelf cell therapies for patients with hematologic malignanies and other critical diseases, announced the second closing of its Series B financing, bringing the total amount raised in this round to $56 M. [company press release, Jul 11, 18] also announced that the U.S. Food and Drug Administration (FDA) has granted Nohla’s lead product candidate, dilanubicel (NLA101), Orphan Drug Designation for reduction of morbidity and mortality associated with hematopoietic stem cell transplant (HSCT). [company press release, Jul 16, 18] total funding $120M [crunchbase.com]

Vaccinex (Rochester, NY; $4.4M SBIR, founded 2001), developing antibody therapies to combat cancer and neurological diseases, filed [for IPO] to raise up to $46 million [nasdaq.com, Jul 16, 18] total funding $12M [crunchbase.com]

C-Motive Technologies (Madison, WI; $1.6M SBIR, founded 2012) startup that’s seeking to commercialize a new type of electric motor that it claims will produce less heat and can be built with lighter materials than the motors currently on the market, like those made with cobalt. “We’re eliminating the rare earth magnets" says [CEO] Justin Reed. The company recently raised a $750,000 round of convertible debt financing from a group of angel investors, Reed says. [xconomy.com, Jul 16, 18]

Biolife Solutions up 10% [Jul 13, 18]

SCYNEXIS (Jersey City, NJ; $400K SBIR, market cap $90M), developing innovative therapies for difficult-to-treat and often life-threatening infections, announced positive results from its Phase 2b, dose-finding study (the DOVE study) evaluating oral SCY-078 for the treatment of vulvovaginal candidiasis (VVC). SCY-078, the first representative of a novel oral and intravenous triterpenoid antifungal family, is in clinical development for the treatment of multiple serious fungal infections, including VVC, invasive candidiasis (IC), invasive aspergillosis (IA) and refractory invasive fungal infections. [company press release, Jul 10, 18]

II‐VI (Saxonburg, PA; $3M SBIR, market cap $2.7B), a leading provider of solutions for optical networks, today announced that in order to address increased demand for its differentiated product portfolio, it plans to expand the capacity of its 980 nm pump laser production lines, including wafer fab and chip on carrier assembly in Zurich, Switzerland and in Calamba, Philippines, and pump laser module assembly in Shenzhen, China. [company press release, Jul 9, 18]

Elixirgen Therapeutics (Baltimore, MD; no SBIR) raised $4 million in a Series A funding round from University of Tokyo Edge Capital (UTEC). .... a biotech focused on curing humanity’s ailments through innovations in stem cell biology. [company press release, Jul 9, 18]

While top companies are getting more productive, gains are stalling for everyone else. And the gap between the two is widening .... Since the 2008 financial crisis, U.S. productivity has grown by about 1.2% a year. half the rate it clocked in the 1970s and around one-third of what it was in the decades after World War II, once adjusted to strip out the temporary effects of economic booms and busts. [Jason Douglas, Jon Sindreu and Georgi Kantchev, Wall Street Journal, Jul 15, 18] The economic effects of the 2008 crash caused the political revolt that got Trump elected, who the economists would also say has no workable solution, including "America Alone".

Carelessly Unintended Consequences. Profits are soaring, but paychecks are stagnant. Companies complain about a shortage of workers, but they seem reluctant to raise wages. A sinking nationwide unemployment rate masks many of the struggles workers face: Hourly earnings have moved forward at a crawl, with higher prices giving workers less buying power than they had last summer. Unions are weakening, and companies have the ability to look for cheaper workers overseas. [JOUMANA KHATIB AND LANCE BOOTH, New York Times, Jul 13, 18] Maybe the deplorables will discover the obvious - only the rich matter.

"We find tax cuts lead to higher reported capital income and a decrease in wage and salary income. These effects are concentrated among top earners, and we find no effects for those reporting less than $200,000 in income," the authors [Ethan Rouen of Harvard Business School and Suresh Nallareddy and Juan Carlos Suárez Serrato of Duke University] wrote. [Fiscal Times, Jul 13, 18] You of course are free to believe the econo-rantings of the Libertarian Knights of Over-Taxed Wealth. They voted against the woman by overlooking the charade of the alternative.

Zogenix (Emeryville, CA; no SBIR, market cap $1.6B) up 21% [Jul 12, 18] reported positive top-line results from its second confirmatory Phase 3 study (Study 1504) for its investigational drug, ZX008 (low-dose fenfluramine hydrochloride), for the treatment of children and young adults with Dravet syndrome. [company press release, Jul 12, 18]

Biolife Solutions up 10% [Jul 12, 18]

Otsuka Pharmaceutical (Japan) is expanding its pipeline and U.S. reach with an agreement to acquire clinical-stage drug developer Visterra (Waltham, MA; one SBIR, founded 2007) for $430 million cash. [Frank Vinluan, xconomy.com, Jul 11, 18] total funding $125M [crunchbase.com]

Mr Know-it-all. “I would have done it much differently,” Mr. Trump said. “I actually told Theresa May how to do it, but she didn’t listen to me.” [CHRIS STANFORD, New York Times,, Jul 12, 18] After all, who needs allies when he knows it all and doesn’t want to fix international institutions, just destroy them [Paul Krugman, NYT, Jul 12, 18]? For thinking about consequences of Trumpism, read the history of the US 1890s Gilded Age.

AXT up 15% [Jul 11, 18]

Myriad Genetics up 13% [Jul 11, 18]

BioCryst Pharmaceuticals (Durham, NC) is ending a plan to merge with Idera Pharmaceuticals and form a single company focused on rare diseases. ... following a meeting that saw shareholders vote overwhelmingly against the proposal. [Frank Vinluan, xconomy.com, Jun 10, 18]

Endless growth arguments. A new analysis from the Federal Reserve Bank of San Francisco suggests that most growth estimates are too generous, and the U.S. economy may not see much additional growth in the wake of the tax cuts. [Yuval Rosenberg and Michael Rainey, Fiscal Times, Jul 11, 18] The taxcutters project what they want to hear, and the professional economists seek valid estimates. The US economy is so large and complex that estimates have wide confidence bands. Bottom line: the wealthy got what they paid a lot for, and the unwealthy will have to take whatever is left over. Whatever happens, the federal Treasury will be in ever growing debt as the nation endlessly spends on its imaginary credit card faster than it collects revenue to pay for its purchases. How depressing the the so-called conservative Republicans created the financial mess to encourage wealthy supporters to pay the Republican re-election campaign bills.

Gevo down 10% [Jul 10, 18]

A CTI BioPharma (formerly Cell Therapetics, Seattle, WA; no SBIR) treatment for a form of non-Hodgkin lymphoma has failed a clinical trial key for maintaining its approval in Europe, casting doubt on the drug’s prospects with the FDA... said its drug, pixantrone, failed to meet the goal of improving progression-free survival, which is the length of time a patient lives without the disease worsening. [Frank Vinluan, xconomy.com, Jul 9, 18] total funding $85M [crunchbase.com]

A drug [luspatercept, as a treatment for beta-thalassemia] from Celgene and Acceleron Pharma (Cambridge, MA; no SBIR) has met the main goals of a late-stage test as a treatment for a rare blood disorder, the second set of positive results that the partners have released for the drug in as many weeks. [Frank Vinluan, xconomy.com, Jul 9, 18]

Dynacure [French, founded 2016) raised $55M to take an antisense oligonucleotide therapy into the clinic. ... the centronuclear myopathy (CNM) prospect from its cofounder, Ionis Pharmaceuticals. [Nick Paul Taylor, Fierce Biotech, Jul 6, 18]

Athenex is picking up $100 million, licensing a cancer-fighting enzyme and launching a new Chinese joint venture built around T-cell receptor tech. [Amirah Al Idrus, Fierce Biotech, Jul 2, 2018]

Thomas Jefferson University (Philadelphia, PA) with a national reputation for transdisciplinary learning and innovation, and BioVaxys LLC (NYC, NY; no SBIR), clinical stage biotechnology company, announced they have entered into an exclusive worldwide license agreement for a technology comprising highly-targeted, patient-specific, immunotherapeutic vaccines to treat ovarian cancer, melanoma, and other solid tumor types. [Thomas Jefferson press release, Jul 9, 18]

Pulmonx® (Redwood City, CA; no SBIR, founded 1998) announced that [FDA] approved the Zephyr® Endobronchial Valve System for treating severe emphysema patients. ... the first minimally-invasive device approved in the US for treating patients with severe emphysema, a progressive and life-threatening form of chronic obstructive pulmonary disease (COPD). [company press release, Jun 29, 18] total funding $99M [crunchbase.com]

Gevo up 19% [Jul 9, 18]

Innovate Biopharma up 14% [Jul 9, 18]

CTI Biopharma down 14% [Jul 6, 18]

Xenetic Biosciences down 12% [Jul 6, 18]

Biodesix (Boulder, CO; no SBIR), a molecular diagnostics company, announced that [it] acquired Integrated Diagnostics (Seattle, WA; $1M SBIR) The agreement includes the XL2 test, Indi’s lead oncology product, which offers a noninvasive means of ruling out cancer for patients with suspicious lung nodules. Financial terms not disclosed. [Biodesix press release, Jul 9, 18]

miRecule (Gaithersburg, MD; $300K SBIR, founded 2016) raising $1M to stop cancer tumors , using microRNA therapeutics to treat cancers [Sara Gilgore, Washington Business Journal, Jul 3, 2018]

Becton, Dickinson announced it has completed the acquisition of TVA Medical (Austin, TX; no SBIR) that develops minimally invasive vascular access [FDA approved] solutions for patients with chronic kidney disease requiring hemodialysis. [BD press release, Jul 9, 18]

The British Business Bank, a public company owned by the U.K. government, unveiled last week a £2.5 billion fund called British Patient Capital that will make long-term investments in technology companies and others with high potential for growth. [Science, Jun 29, 18]

Venture capitalists now talk about “kill zones”, areas they will not invest in because one of the big players may squeeze the life out of startups or buy them up at a low price. [The Economist, Jun 29, 18]

Innovative muscles. He snipped a tiny piece of muscle from the baby’s abdomen. Dr. McCully grabbed it and raced down the hall. Twenty minutes later, he was back with a test tube of the precious mitochondria. Dr. Emani used an echocardiogram to determine where to inject them. He injected a billion mitochondria, in about a quarter of a teaspoon of fluid. Within two days, the baby had a normal heart, strong and beating quickly. ... The baby had had a heart attack, [at Massachusetts General Hospital] most likely while she was still in the womb. Her heart was profoundly damaged; a large portion of the muscle was dead, or nearly so, leading to the cardiac arrest. [Gina Kolata, New York Times, Jul 9, 18]

Microsoft is setting up an [medical] innovation hub in Durham's Chesterfield building so its scientists and Duke University's can work together. [Raleigh News & Observer, Jul 9 18]

Trump's shrinkgov plan Creating an energy innovation office to handle applied research programs at the Department of Energy (DOE) could improve coordination—but some groups see it as a way to dismantle DOE's Advanced Research Projects Agency-Energy. Trump ran on a pledge to shrink government, but to date he has shown little interest in winning over the law-makers who hold sway over such changes. ... But like previous reshuffling attempts by his Democratic and Republican predecessors, the plan is likely to face a tepid response from Congress. [Science, Jun 29, 18] Trump wins with his base when he thunders some grand pronouncement, true or false, that creates lightning. He will need continual thundering to divert attention from the many things that nevr happen or do more harm than good.

Competition and trade-war catching up. Xiaomi’s public debut was supposed to value the Chinese gadget maker at $100 billion and set the stage for a global coming-out party for some of China’s most successful technology companies. When Xiaomi finished its first day of trading, the company was worth only $48 billion, weakness that could hang over the rest of the Chinese tech players waiting to go public. [Alexandra Stevenson, NY Times, Jul 8, 18]

Xenetic Bio up 22% [Jul 6, 18]

Restoration Robotics down 11% [Jul 6, 18]

Innovate Biopharma down 10% [Jul 6, 18]

Tricida down 10% [Jul 6, 18]

CoolTech (Baltimore, MD; no SBIR, founded 2011) looks to raise $3M, plans for clinical studies [Morgan Eichensehr, Baltimore Business Journal, Jul 5, 18] develops CoolStat, a novel trans-nasal energy removal technology used for cooling for prehospital cardiac arrest. Total funding $2M [crunchbase.com]

In the Archives older stories back to 1996

news and views about government programs, politics, attitudes ...1996-1997; 1998; 1999; Y2K; 2001 , 2002-2003 ; 2004-5; 2006; 2007-08 2009-2010; 2011-2012; 2013-14 ; 2015; 2016; 2017-18

BMDO/ MDA including SBIR the doings of star wars

Miscellaneous Stories 1996-1997; 1998-1999; 2000-2001; 2002-2003 ; 2004-5 ; 2006; 2007 2009-2010 ; 2011-2012; 2013-2014; 2015; 2016; 2017

IPO and Venture Markets 1996-1998 .... 1999-2005 ... 2006-present

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10X Genomics ..... 1366 Technologies ... 1st Detect ... 21-Century Silicon ... 21st Century Systems .... 23andMe ... 24M Technologies ... 30 Second Software ... 360fly ..... 3Bar Biologics .... 3C Semiconductor ... 3D Glass Solutions ..... 3Dnamics ..... 3D Robotics .... 3D Systems ..... 3D Technology Laboratories .... 3F ... 3PrimiR ... 3Scan ..... 3-V Biosciences .... 3VR ... 410 Medical Innovation .... 454 Life Sciences .... 4C Medical Technologies .... 4s3 Bioscience ... 5D Robotics ..... 7AC Technologies ... 908Devices ... 9Mile Labs

A10 Networks ... A123Systems ... A&G Pharmaceutical ... Aastrom Bioscience .. Abacus Technology ... ... Abaxis .... Abcombi Sciences ..... Abeona Therapeutics ..... AbGenomicsInternational ... Abiomed ... Ablexis ...... ABL Technologies .... Abpro Therapeutics ..... AbSci .... Absorbent Materials ... Abundant Robotics ..... AbVitro ... Acadia Pharma ... Acambis .. Accel Diagnostics ..... Acceleron Pharma ... Accelrys ... Accentia BioPharmaceuticals ... Accent Therapeutics ..... Accera .... Access Pharmaceuticals ... Access Scientific .... Accion Systems ..... Accumetrics ... AccuraGen ..... Accurate Automation .. Accuray ... Accuri Cytometers ... Acelerox .... Acelity .... AcelRx Pharmaceuticals ... Acera Surgical .... Acetylon Pharmaceuticals ... Achaogen ... Achates Power ..... Achillion Pharmaceuticals ... ACIST Medical Systems .... Acorda Therapeutics ... Acorn Cardiovascular ... Acquia .... AcroMetrix ... AcryMed ... ActaCell ... Actasys .... ACT Biotech ... Active Power ... ActivBiotics ... ActivMedia Robotics .... Acton Pharmaceuticals ... Actuality... Acucela ... AcuFocus .... Aculight ... Acumentrics ... AcuraStem .... Acutus Medical .... Adamas Pharmaceuticals ...... Adamis Pharmaceuticals ... Adapteva .... Adaptimmune Therapeutics .... Adaptive Biotechnologies ..... Adaptive Computing ... Adaptive Phage Therapeutics ..... Adaptive TCR ... Adarza BioSystems ..... Addiction Therapeutix ... Addrenex Pharmaceuticals ... Adelor ... Adenosine Therapeutics ... Adesto Technologies .... Adeza Technologies ... Adherex Technologies ... Adhesys Medical .... Adial Pharmaceuticals .... Adicet Bio .... AdiMab ... ADispell ... Adlyfe .... Admittance Technologies .... Admune Therapeutics ..... Adnexus Therapeutics ... Adrenergics .... Advanced BioHealing ... ADS Biotechnology ... Aduro BioTech .... Advanced Animal Diagnostics .... Advanced Biologics ..... Advanced Bionics ... Advanced Cell Diagnostics ... Advanced Cell Technology (now sub to Bio-Techne) ... Advanced Ceramics .... Advanced Circulatory ..... Advanced Countermeasures Systems ... Advanced Diamond Technologies .... Advanced Electron Beams ... Advanced Fuel Research ...Advanced Life Sciences ... Advanced Lighting Technologies ... Advanced Liquid Logic ... Advanced Magnetics ... Advanced Photonix .... Advanced Programming Concepts ... Advanced Receiver Technologies .... Advanced Scientific Concepts ..... Advanced Targeting Systems .... Advanced Technology Materials.(ATMI) ... Advanced Uro-Solutions ..... AdvanDx ... Advantic ..... Advaxis ..... Adventrx ... Adverum Biotechnologies ..... Advion BioSciences ... Adynxx ...... Aegea Medical ... Aegerion Pharmaceuticals .... Aeglea BioTherapeutics Holdings ..... Aerial BioPharma .... Aerie Pharmaceuticals ... Aerin Medical ..... AerisPhotonics ...... Aerius Photonics ... Aerodyne Research ... Aero Farms System ... AeroVironment ... Aerpio Therapeutics .... AesRX ... AETC ... Aethlon Medical ... Aethon .... Aevi Genomic Medicine ..... Affectiva .... Afferent Pharmaceuticals ..... Affigen .... Affinimark Technologies ... Affinity BioReagents ... Affinium Pharmaceuticals ..... Affinivax .... Affomix .... Affymax ....Affymetrix ... aFraxis ... AgBiome ..... AgeneBio .... Agennix ... Agenovir ..... Agenus .... Agere Pharmaceuticals ..... Agile Materials ... Agile Planet ... AgileSwitch .... Agile Therapeutics .... Agility Robotics ..... Agiltron...Agilvax .... Agilyx .... Aagios Pharmaceuticals... AgraQuest .... Agritope... Agrivida ... Agro Biosciences .... Aguila Technologies.....Ahura Scientific.... Aiko Biotechnology ... Aileron Therapeutics .... Aimmune Therapeutics (formerly Allergen Research) ..... airtricity... Airware .... Airxpanders .... Airway Therapeutics .... ait laboratories... Akadeum Life Sciences .... Akamai Physics Akarna Therapeutics ..... Akashi Therapeutics ..... Akcea Therapeutics ..... Akebia .... akermin ..... Akers BioScience ..... Akita Innovations ... Akron Polymer Systems ..... Akron Surface Technologies ..... Akros Medical .... Alabama Cryogenics ... Alafair Biosciences .... Albany Molecular (AMRI) ...A? nanotech .... Alcon .... Alcresta .... Aldagen ... Aldatu Biosciences ..... Aldea Pharmaceuticals ... . Alder biopharma Aldevon ..... Aldeyra Therapeutics (formerly Aldexa Therapeutics) .... Alector .... Alexar Therapeutics ..... Alexion ... ....Alexza .... Alfalight.... Algaeventure Systems ... Algenetix .... Algeternal .... Algorithmia ..... Alien Technology .... Alimera sciences.... Alios BioPharma ....Aliva biopharmaceuticals ..... Alivio Therapeutics ..... Alkermes... Alkeus Pharmaceuticals ... Allakos ... Allcast .... Allegro Diagnostics .... Allegro microsystems ... Allena Pharmaceuticals .... Allergy Amulet ..... Allerquest .... Alleviant Medical .... Allied BioScience ..... Allied Minds .... Alliqua .... Allos Alloy Polymers .... Alloy Surfaces ..... Allurion Technologies ... Allylix ... Alnara Pharmaceutical ... Alnylam... Alper Biotech ... Alphabet Energy .... AlphaCore Pharma ... Alphamed.... Alphatec Holdings ..... Alphavax ... Alpine Biosciences .... Alpine Data Labs .... Alpine Immune Sciences ..... Alseres .... Algeternal .... Alta Devices ... AltAir Fuels ... Altair Therapeutics ... Altamira Technologies .... AltaRock ... AltheaDX .... Althea Technologies ... Altimmune ..... Altor ... Altra ... Altura Medical ... Altus Pharmaceuticals ... ALung Technologies ... Alvine Pharmaceuticals .... Alzeca ..... AMAG Pharmaceuticals ... Alzheon ..... Amaranth Medical .... Ambarella ..... Amberwave ... Ambiq Micro .... Ambit Biosciences .... AMBP Technology ... Ambri .... Ambrx ... Ambry .... Amendia .... American Bionics ..... American Gene Technologies International .... American Lithium Energy .... American Medical Systems .... American Science and Engineering ... America Stem Cell, now Targagyme .... American Superconductor ... American XTAL .. Ames Technology ... Amgen ... Amicus Therapeutics .... Amionx ..... Amnis ... AMO Pharma ..... Ampio Pharmaceuticals ..... Ampla Pharmaceuticals ... Amplimmune .... Amplyx Pharmaceuticals ..... Amprius .... ARMO BioSciences .... Amylin Pharmaceuticals ... Amylyx ..... Amyris Biotechnologies ... Anacor Pharmaceuticals ... Anadys Pharmaceuticals ... Anakim Biologics .... Analog Computing Solutions .... Analytical Space ..... AnaptysBio ... Anavex Life Sciences .... Anchor Therapeutics ... Ancora Pharmaceuticals ... AnDAPT ..... Anexon .... Anew Optics ... Angeion ... AngioDynamics ... Angiologix ... Angstrom Medica .... Angstron Materials ... Animalgesic Labs .... ANI Pharmaceuticals ... Animetrics .... Anivax .... Anivive Therapeutics ..... Annexon Bioscience ..... ANP Technologies ..... Ansoft ... Ansun Biopharma (formerly NexBio) .... Antegrin Therapeutics ..... Anthera Pharmaceuticals .... Antigenics ... Anue Systems ... Anulex Technologies ... Anybots ... AOBiome Therapeutics (formerly Nitrocell) .... AOptix Technologies ... Aortica ..... APA Optics (Enterprises) ... Apellis Pharmaceuticals ..... Apexigen ... Aperion Biologics .... Aphios ... Apieron ... Apnex Medical ... ApniCure ..... ApoCell .... ApoGen Biotechnologies .... Apollo Diamond ... Apollo Endosurgery ... Apoplogic Pharmaceuticals ... Applied Biomolecular Technologies .... Applied Biosystems .... Applied Defense Solutions ..... Applied Genetic Technology ... Applied Nanotech .... Applied NanoWorks ... Applied Optimization ..... Applied Optoelectronics ... Applied Physical Electronics ... Applied Physical Sciences ... Applied Precision ..... Applied Proteomics ..... Applied Quantum Technologies .... Applied Quantum Technology .... Applied Research Associates ... Applied Science and Technology ... Applied Signal Technology ... AppThwack .... Aprecia Pharmaceuticals .... Apricus Biosciences ... APS BioGroup .... Apse .... Aptalis Pharma .... Aptevo Therapeutics ..... Aptima ... AptamiR Therapeutics .... Aptinyx .... Aptose Biosciences .... Aptus Endosystems ... Aquaback Technologies ... Aqua Bounty ... Aquacue .... AquaHarmonics ..... Aqua Metals .... AquaMost ... Aquarius Technologies ... AqueSys ... Aqueti .... Aquion .... Aradigm .... AragonPharmaceuticals ... Aratana Therapeutics ..... Arbor BiotechnologieArbor Pharmaceuticals ... Arbovax ... Arbutus BioPharma (formerly OnCore) ..... Arca Biopharma .... Arcadia Biosciences ..... Arcadia Pharma ..... Arcantatura... Archemix ... ArcherDX ......Arch Innotek ..... Arch Therapeutics ... Arctic Sand Technologies .... Arcturus Therapeutics .... Arcus Biosciences ..... Ardea Biosciences ... Ardelyx .... Ardian .... Arena Pharmaceuticals ... Argentum ..... Arginetix ... Argo AI ..... ArgonST ... Argos Therapeutics ... Aria CV ... Ariad Pharmaceuticals .. Ariosa Diagnostics ..... Arista MD .... Arista Networks .... Arkis BioSciences Arkansas Power Electronics ..... Armadillo Aerospace ... Armetheon .... ARMO BioSciences .... Armonica Technologies .... 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Astrum Solar ... Astute Medical .... Astute Medicales ... Asuragen ... Atacama ..... Atara Biotherapeutics ..... Ataxion .... Athenex (formerly Kinex) ..... Athenix ... Athens Research ..... AtheroGenics ... AtheroMed .... Athersys .... ATI Industrial Automation ... Atlantia ... Atmocean ..... Atmospheric Glow Technologies ... Atomate ... Atomic Medical Innovations ..... Atomometrics ... Atomwise ..... Atoptix .... Atossa Genetics ... Atreaon .... Atreon Orthopedics ..... AtriCure ... Atrium Medical ... ATRP Solutions ... aTyr Pharma ..... Audentes Therapeutics ..... Audience ... Augmenix .... AUM Cardiovascular ... Aura Biosciences .... Auris Medical .... Auris Surgical Robotics ..... Aurora Algae ... Aurora Flight Sciences .... Aurora Imaging Technology ... Aurora Spectral Technologies ... Auspex Pharmaceuticals ... Ausra ... Auterra .... AuthenTec .... Automated Dynamics ... Automated Medical Instruments .... Autonet ... Aushon Biosystems ... AutoGenomics .... Autonomic Materials .... Autonomic Technologies ..... Autonomous Technologies .... Auxilium Pharmaceuticals ... Avalanche Biotechnologies .... Avanir Pharmaceuticals ... Avant Immunotherapeutics ... Avanti Metal ... Avaxia Biologics ... Avedro ... Avelas Biosciences .... Aveo Pharmaceuticals ... Avery Therapeutics ..... AveXis .... Aviation Resources Delaware .... AVI BioPharma ... Avici Systems ... AvidBiotics .....Avidity Biosciences .... Avid Radiopharmaceuticals ... Avila Therapeutics ... Avinger .... ... Aviragen Therapeutics (formerly Biota Pharmaceuticals) ..... Aviron ..... Avita Medical Americas ..... Avitude .... Avrobio ..... AVT Simulation .... Aware ... Axcella Health (was Pronutria) ..... Axelo .... Axerion Therapeutics ... Axial Biotech .... Axial Biotherapeutics ..... Axion BioSystems ..... Axion Power ... Axis Clinicals .... Axis Semiconductor ... Axium Nanofibers ...... Axium Pharmaceuticals .... Axogen .... Axonia Medical ... Axsun Technologies ... Ayasdi ..... Azaya Therapeutics ... Azelon Pharmaceutical ... Azimuth .... Aziyo Biologics ..... Azure Biotech

Bacterial Robotics .... BacterioScan .... Baebies ..... Bagaveev .... Ballard Power ... Bamboo Therapeutics ..... Bandgap ... Banyan Biomarkers ... BarioSurg ..... Baryonyx .... Barrier Therapeutics ... Baseload Renewables .... Basis Science .... Bastion Technologies .... Batu Biologics ..... Bauhaus Software ..... Baxano ... Baxano Surgical .... BayoTech ..... Beacon Biomedical ..... Beacon Power ... Beam Therapeutics ..... Beat Biotherapeutics .... Beeco ... Behavioral Recognition Systems .... Bellicum Pharmaceuticals .... Belmont Instrument .... Benchmark Automation ... BeneChill ... Benefuel ... BeneVir Biopharm .... Benson Hill Biosystems ..... Benvenue Medical .... Berg .... BerrieHill Research ... BESS Technologies .... BetaBatt ... BetaLED .... LEDBG Medicine ... Bettergy .... Bexion Pharmaceuticals .... Bina Technologies .... Bind Bioscience ... Bind Therapeutics .... BinOptics ..... BiO2 Medical ... BiO2 Technologies ... BioAmber ... BioAdvanTek ... BioAffinity Technologies ..... Bioanalytical Systems ... BioBehavioral Diagnostics ... BioBridge Global ..... BioCardia ..... BioCentra Molecular Innovations ..... Biocept ... BioChemics ..... BioClin Therapeutics .... Bicycle Therapeutics ..... Bioconnect Systems .... BioConsortia ..... BioCritica ... BioCryst Pharmaceuticals ... BioDelivery Sciences ... Biodesix .... BioDirection ..... BioE ... BioFire .... BioFluidica ..... Biogenic Reagents .... BioGreenChoice ... BioHaven Pharmaceuticals ..... Bioheart ... Biohelix ... Bio-Imaging Technologies ... Bioincept .... BioKier ..... Biolex Therapeutics ... BioLife4D ..... BioLink Life Sciences ... Biolinq (formerly Electrozyme) ,,,, Biologics ... BioMagnetic Solutions .... BioMarin Pharmaceutical ... BioMarck Pharmaceuticals .... bioMASON ..... Biomatrica ... BioMedical Enterprises ... Biomedical Sciences ..... Biomedical Structures ... BioMedix .... Biomeme .... Biometric Signature ... BioMimetic Therapeutics ... BioMotiv .... BioNano Genomics ... BioNanomatrix ... Bionostics Holdings ... Bio-Path Holdings ..... Biophan Technologies ... Biophysical ... BioProcessors ... Bioptigen ... Bioptix .... BiOptix Diagnostics ..... BioPulping International ... Biopure ... Biorasis ..... BioRelix ... BioResource International ... BioRestorative Therapies (formerly Stem Cell Assurance) .... BioSante Pharmaceuticals ... BioScale .... BioSense Technologies ... BioSensics .... BioSentinel Pharmaceuticals ... BioSig Technologies ..... Biosortia Pharmaceuticals .... BioSphere Medical .... Biostage (formerly Harvard Apparatus Regenerative Technology) ..... BioStructures .... Biosurfaces .... Biosym Technologies later Accelrys .... BioSystem ... Biota Pharmaceuticals .... Bio-Techne ..... BioTechnique .... BioTechPlex ..... Biotectix .... Biotel .... BioTelemetry (formerly CardioNet) ..... BioTex .... Biothera ... BioTheranostics ... Bio Time ... Biotix ... Biotronic NeuroNetwork ..... Biotronik .... BioTrove ... Bioventus ..... Biovest International .... BioVex ... BioVirtua ..... Bird Rock Bio (formerly RuiYi) ..... Birich Technologies .... Bitstream ... Black-I Robotics ... Black Sand ... BlackThorn ..... BladeLogic ... Blasch Precision Ceramics .... Blaze Bioscience ... Blend Therapeutics .... BL Healthcare ... Block Engineering ... Bloom Energy ... Bloo Solar ..... BluDiagnostics ..... Blue Belt Technologies ... Bluebird bio ... BluDiagnostics .... Bluefin Robotics ... Bluegrass Proteins .... Bluegrass Vascular Technologies .... Blueprint Medicines ... BlueRock Therapeutics ..... Blue Sky Batteries ... Bluewater Bio International ... Bolt Threads .... Boom Supersonic ..... Boragen .... Boston Biochem ... Boston Biomedical ... Boston Dynamics ... Boston Engineering ... Boston Micromachines ... Boston-Power ... Boston Therapeutics ... Bot Dolly .... Boundless ... BoXZY ..... Braeburn Pharmaceuticals ..... BrainCells ... BrainScope .... Brain Sentry .... Brain Tunnelgenix Technologies .... BrainXell ..... Branch Medical Group ..... Brayton Energy .... Breathe Technologies ... Breethe .... Breonics ... BreviTest Technologies ..... Brewer Science ... Bridger Photonics .... Bridgelux ... Brightsource Energy ... Bright View ... Brimrose Corp of America ... Briteseed .... Brock Rogers Surgical ... Bromium .... Brooks Automation ... Bruker Daltonics .... Buffalo BioLabs ..... Burl Concepts ..... Burr Oak

C12 Energy ... C2Sense .... C3Nano ... C4 Therapeutics .... C8 Sciences .... C9 ... CABG Medical .... Cadence Pharma .... CadheRx Therapeutics ..... Caisson Biotech .... Calabazas Creek Research .... Caladrius Bioscience ... Cala Health ..... Calando Pharmaceuticals ... Calbiotech .... Calera ... Caliber Biotherapeutics .... Calibra Medical ... Calient ... California Wave Power Technologies ..... Calimmune ..... Caliper Life Sciences .... CaliSolar ... Calistoga Pharmaceuticals ... Calithera BioSciences .... Calixa Therapeutics ... Callidus Biopharma ... Calporta Therapeutics .... Calspan .... Caltech Metals ... Calysta .... Calyxt ..... Cambridge Endoscopic Devices ... Cambridge Heart .... Cambridge Research & Instrumentation ... Cambrios Technologies .... CAMX ..... Candela Laser .... Cancer Genetics .... Cancer Prevention Pharmaceuticals .... CanDiag .... Canopy Biosciences ..... Capesym ... Capio Biosciences .... Capnia ... CAPP Medical ..... Capricor Therapeutics .... Cara Therapeutics .... Carbon ..... Carbon Design Systems ... Carbtex Technology .... Carbylan Therapeutics ..... Cardeas Pharma .... CardiacAssist ..... Cardiac Concepts ... Cardiac Dimensions ... Cardiac Science ..... Cardialen ..... CardiAQ Valve Technologies ... Cardica ... CardioDx ... CardioFocus ... CardioInsight Technologies ..... Cardiokinetix ..... CardioMag ... CardioMEMS .... Cardionomic .... CardioNXT ..... Cardiorobotics ... Cardiosolutions ... Cardiosolv .... CardioSpectra ... CardioTech ... Cardiovate ..... CardiOx ... Cardioxyl Pharmaceuticals .... CareDx (formerly XDx) .... Caribou Biosciences ..... Carigent Therapeutics .... Carisma Thera (formerly CARMA Therapeutics) ..... Carmot Therapeutics ..... Carnegie Robotics .... Carnegie Speech ... CaroGen .... Carter Aviation Technologies .... Carticept Medical ... Cartiva ..... Cascade Designs ... Cascade Microtech ... Cascadian Therapeutics (formerly Oncothyreon) ..... Casma Therapeutics .... Castle Biosciences ..... Catabasis Pharmaceuticals ... Catadon Systems ... Catalyst Biosciences ... Catalytic Innovations ..... Catalyze ..... Catelectric .... Cebix .... Cedarburg Pharmaceuticals .... Cedilla Therapeutics ..... CeeTox ... Celadon ... Celator Pharmaceuticals ... CelcuityCeldara Medical ..... Celladon .... Cellara .... Cellceutix .... CellCyte Genetics ... Cell Design Labs ..... Celldex Therapeutics ... ..... Cellectar ... Cellerant Therapeutics ... Celleration .... Cell Genesys ... CellRight Technologies ..... Cellular Bioengineering ... ... Cellular Bioengineering ..... Cellular Biomedicine Group ..... Cellular Dynamics International .... Cell>Point .... CellSavers ..... Cellscape .... Cellscript ..... Cell Signaling Technology ...Cell Therapeutics (now CTI BioPharma) ... CellTraffix ... CeloNova Biosciences ..... Cel-Sci .... Celsion ... Celtaxsys ..... Celula..... Celularity ..... CellzDirect ... Cempra Pharmaceuticals. .... CeNeRx BioPharma ... Centocor .... Centrexion Therapeutics ..... Centrose ... Centice ... Centritec Seals ... Cephalon ... Cepheid ... Cephalon ... Ception Therapeutics ... Cequent Pharmaceuticals ... Cerebras Systems ..... Ceradyne ... Ceramitron ... Cerapedics .... Ceramatec ... Cerevast Therapeutics .... Cerealus Holdings ... Cerecor .... Ceregene ... Cerahelix .. Ceres Nanosciences ..... Cerexa .... Cerion Enterprises ... Cermet ... Cernostics ..... Cerulean Pharma ... Cerus ... Cervel Neurotech .... Cesca Therapeutics .... Ceterix Orthopaedics ... CFD Research .. CFX Battery .... CGI Pharmaceuticals ... ChaCha ... Chantilly BioPharma .... Chapman Innovations ... Charles River Analytics .... Charles River Lab ... Charter Medical ..... Chatham Therapeutics ..... Checkerspot ..... Chemat ... Chembio Diagnostic Systems .... ChemImage ... Chemir Analytical Services ... ChemoCentryx ... Chemtura .... Chesapeake Sciences ...Chesson Labs ... Chiasma .... Chimera Bioengineering ..... Chimerix ... Chlorogen ... Choice Therapeutics ... Chondrogenics ... Chordia Therapeutics .... Chorum Technologies .... ChromaCode ..... ChromaDex ..... Chronix Biomedical ... Chrysalis BioTherapeutics .... Cibus Global ... Cidara Therapeutics .... Ciena ....Ciencia ... Cilion .... CimaBay Thera ..... CinRx .... Ciranova ... Circle Technologies ..... Cirius Therapeutics ..... CivaTech Oncology .... CiVi Biopharma ..... Civitas Therapeutics ..... Claret Medical .... Clarassance ..... Claresta Solutions .... Clark-MXR ...Claros Diagnostics .... Clean Diesel Technologies ... Clear Catheter Systems .... ClearCount Medical Solutions .... ClearEdge Power .... Clear Guide Medical .... Clearside Biomedical ... Cleave Biosciences ... Cleveland BioLabs ... Cleveland Polymer Technologies ..... CleverSet ... Clinical Data ... Cloudant ... CloudMade ... Cloud Pharmaceuticals (formerly Teradiscoveries) .... Clovis Oncology ... Clovis Tech ..... CMC Biologics .... C-Motive Technologies .... CoAdna,Holdings ..... CoAxia .... Cobalt Biofuels ... Cocrystal Discovery ... Codexis ... Codiak BioSciences ..... Codon Devices ... Co-D Therapeutics .... Cofactor Genomics .... Cogenra .... Cogentix Medical ..... Cognex ...Cognition Therapeutics .... Cognitive Code ... Cohera Medical .... Coherus Biosciences .... Cohesive Technologies ... ColdWatt ... Collagenex Pharmaceuticals ... Collegium Pharmaceutical ... CoLucid Pharmaceuticals ... Columbia Labs ..... CombiMatrix ... CombinatoRx ..... Combined Energies .... Combinent BioMedical Systems ... Comfort Motion Technologies ... Commonwealth Biotechnologies ... Compact Membrane Systems ... Compellent Technologies ... Compendia Bioscience ..... Complete Genomics .... Complexa ..... Conatus Pharmaceuticals ... Concert Pharmaceuticals .... Concordia Fibers ...Concurrent Technologies ... Conductus .. Confluence Life Sciences ..... ConforMIS ... Cognigen .... Conispire .... ConjuGon .. Connecticut Valley Bindery ... Consonus Technologies ... Constellation Pharmaceuticals .... Context Therapeutics ..... Contour Energy Systems ControlRadSystems ..... Conventus Orthopaedics ..... Convergen ... ConverGene .... Convio .... Convoy Therapeutics .... Cool-Bio .... CoolCAD Electronics .... CoolChip Technologies .... Cool Earth Solar .... Cooligy ... Corbus Pharmaceuticals ..... Corcept Therapeutics ... Cordex Systems .... CoreStreet ... CoreTek ... .Corgenix Medical ... Corindus ....Corinthian Ophthalmic ... Corium International .... Corixa .... CorMatrix Cardiovascular .... Cornami ..... Cornerstone Research ... Cornerstone BioPharma then Cornerstone Therapeutics ..... Cornerstone Therapeutics .... Coronado Biosciences ... CorQuest Medical ..... Correx ... Corridor Pharmaceuticals ... Cortana ..... Cortendo AB ..... Cortexyme .... Corvidia Therapeutics ..... Corvus Pharmaceuticals ..... CosmosID ..... CoStim Pharmaceuticals .... Cougar Biotechnology ... Coulbourn Instruments .... Coulter Pharmaceuticals ... Cour Pharmaceutical Development .... Coverity ..... Creare ... Creative Hybrid Solutions .... Creatv MicroTech .... Cree Research ... Crescendo Bioscience .... Crinetics Pharmaceuticals .... CrispTek .... Critical Therapeutics .... CritiTech ... Crossbar .... Cross Current ..... CrossFire ... Cruise Automation .... Crux Biomedical ... CryoCor ... CryoLife ... Cryomedical Sciences ..... Cryptonite ..... Crystal IS ... Crystal Systems ... Crystallume ... CSA Engineering ... CS-Keys ... CTD Holdings ..... CTI BioPharma (formerly Cell Therapeutics) .... Cubist Pharmaceuticals ... Cue Biopharma .... Cumberland Pharma .... CuraGen ... Current Motor ... Curtana Pharmaceuticals .... Custom Electronics .... CVD Equipment ..... CVRx ... CV Therapeutics ... Cyanotech ..... Cyberdyne .... CyberKey Solutions ... Cyberkinetics Neurotechnology ... Cybernet Systems ... CyberOptics ... Cydan .... Cykloburn Technologies ..... CymaBay Therapeutics .... Cymbet ... CyMedica Orthopedics ..... Cymer ... Cynosure ... Cyntellect ... Cypher Genomics ... CyPhy Works ... Cypress Bioscience ... Cyrus Biotechnology ..... Cyteir Therapeutics ..... Cyterix Pharmaceuticals ... CytImmune .... CytoBioScience ..... Cytocentrics ..... CytoCore (formerly Molecular Diagnostics) ..... Cytocybernetics ..... CytoDyn .... Cytogel Pharma .... Cytokinetics ... Cytometix ....CytomX ... Cytonome .... Cytori Therapeutics ... Cytophil CytoSolv ... Cytosorbents ..... Cytovas ... CytRx ..... Cytyc ... CyVek

Dabble ..... Dairyvative Technologies ..... Daktari Diagnostics ... Dance Biopharm .... Dara BioSciences ... Daré Bioscience Operations .... Dart Therapeutics ... DaStrong .... Datafiniti .... Data Physics ... DataRobot ..... Dato (formerly GraphLab) .... Datuit .... daydream.io ..... Daylight Solutions .... DayStar ... DBS Energy ... DCL Medical Laboratories ... Deca-Medics ... Decibel Therapeutics ..... DecImmune Therapeutics ... Deciphera Pharmaceuticals ..... Decision Biomarkers ... Deepwater Wind .. Defense Engineering .... Defense Research Associates .... Defibtech ... Dekkun .... Delcath ... Delinia ..... Deltanoid Pharmaceuticals ... Denali Medical ... Denali Therapeutics ..... Dendreon ... DeNovo Sciences .... DeNovis ... Deposition Sciences .... DermAvance Pharmaceuticals ... Dermira ... Desalitech .... Descartes Labs ..... Design Knowledge ..... DesignMedix ..... Detcon ..... DE Technologies ... Devicix ..... Dew & Ken Group ... Dewey Electronics ... Dexcom ... Dharmacon ..... Diagnostic Biochips .... Diagnostic Hybrids ... DiaMedica ..... Diamond Foundry ..... Diatomix ..... Dicerna Pharmaceuticals ... Diffusion Pharma ..... DiFusion Technologies ... Digene ..... Digirad ... DigiSight Technologies ..... Digital Fusion ... Digital Lumens ... Digital Optics ... Dignify Therapeutics .... Dimension Therapeutics .... DioGenix .... Dipexium Pharmaceuticals ..... Directed Manufacturing .... Directed Perception .. Disarm Therapeutics .... Disc Dynamics ... Discovery Genomics ..... Discovery Labs .... Displaytech ... Distributed Energy Systems ... Divergence ... Diversified Energy ... D. Light ... DNAnexus ..... DNAPrint Genomics ... DNAtrix .... DNV GL .... Dova Pharma ..... DoX Systems ... Dracen Pharma ..... Dragon Systems .. Dragoon ITCN ..... Drilling Info ... DrillMap .... DropWise .... DR Technologies ..... DrugCendR .... DSM .... DT Solar ... DuBay Ingredients ... duPont Aerospace ... Dura Biotech .... Durata Therapeutics ... Durin Technologies .... DVS Sciences .... DxUpClose .... Dyadic International ..... Dyax ...DynaBil Industries ... Dynasil ... Dynavax Technologies ... Dynetics .... Dynogen Pharmaceuticals

E3 Clean .... Eagle Optoelectronics ... Earl Energy .... EarLens .... Earth Networks .... Earthrise Nutritionals ... eASIC ..... Eboo Pharmaceuticals .... EBR Systems ..... Ebullient .... Echelon .... Echodyne ..... Echometrix ... EchoPixel ..... Echo Therapeutics (was Sontra)... ECI Biotech ... ECM Technologies ..... Ecocurrent ... EcoPesticides .... EcoPro Polymers ..... Eccrine Systems ..... Ecovative Design ... Edaptive Computing .... Eden Bioscience ... Edenspace Systems ... Edge Therapeutics ..... Edico Genome .... Edison Agrosciences ..... Editas Medicine .... EEStor ... Effector Therapeutics .... Egalet .... eGenesis .... Eiger BioPharmaceuticals ..... Eikos ... E-Ink ... EIS .... Ekos ... EKR Therapeutics .... Ekso ... Elcelyx Therapeutics ... Electrical Geodesics ..... ElectroCell Technologies ... ElectroChemical Systems ... Electro Energy ...Electromed ... Electro Optical Sciences ... Electro Scientific ... Elemetric Instruments ... Elevation Pharmaceuticals ... Eleven Biotherapeutics ... Elira Therapeutics ..... Elixir Pharmaceuticals ... Elixir Biopharm ... Ellipse Technologies ..... Elon ... Elstar Therapeutics ..... eMagin .. Embera NeuroTherapeutics .... Embodied .... EmboMedics ..... Embrex .. EMCORE ... Emerald BioStructures .... Emergent BioSolutions ... Emergent Technologies ... Empire Genomics .... Empire Robotics .... EMRes Technologies ... Emulate .... Enable Injections ...... Enanta Pharmaceuticals ..... EnChroma ..... Encite ... Encoded Genomics .... Encompass Bioscience ..... Encore Vision .... Encysive Pharmaceuticals ... Endeavor Robotics ..... Endece ... Endgame Technologies ... EndoChoice .... Endocyte ... EndoGastric Solutions ... Endo International ..... Endoscopic Technologies ... Endosee ..... EndoStim .... Endotherapeutics ..... Ener1 ... EnerG2 ... Energen ... Energesis Pharmaceuticals .... Energetiq Technology ... Energid Technologies ... Energous ..... Ener-G-Rotors ... Energy Control ... Energy Conversion Devices . .. Energy Focus ..... Energy Recovery ... Energy Solutions ... Energy Storage Systems ..... EnerMat Technologies ..... EnerMed ..... Enertech Environmental ... EnerVault ... Engineered BioPharmaceuticals .... Engineered Propulsion ...Engineous Software ... Enlibrium ..... Enlight Bioscience ... EnSync Energy Systems (formerly ZBB Energy) ..... Ensysce Biosciences ... Entasis Therapeutics ..... Entech ... Entegrion ... Entellus Medical ..... Entergem Ventures .... EnteroMedics ... Entia Biosciences ..... Entopica Therapeutics ... EntreMed ... Entra Pharmaceuticals ... ENTrigue Surgical ... Envia Systems .. Entrotech Life Sciences ..... Entvantage Diagnostics ..... EnviroFlight ..... Envisia Therapeutics ..... EnVivo Pharma ... Enzenia ... Enzium ... Enzo Biochem ... Enzymatics ... EnzyMed ..... Enzyvant ..... EO2 Concepts .... EOIR ... Eonix .... EpiBiome .... EpiBone .... Epicentre Biotechnologies .... Epic Sciences .... Epic Systems ..... Epicypher .... EpiEP ... Epion ... Epiphany Solar Water Systems .... Epitomics ... Epiva Biosciences ..... EpiVax ... EpiWorks .... Epix Pharmaceuticals ... Epizyme ... Eppin Pharma .... EqualLogic ... Equex ... Equipment Concepts ... EraGen Biosciences ... Erallo Technologies ... Ercole Biotech ... ERT ..... Escalier Biosciences BV ..... Escalon Medical .... E-Scape Bio ..... Escient Pharmaceuticals ..... Escoublac .... eScription ... eSolar ... Eso-Technologies ... Esperance Pharmaceuticals ..... Esperion Therapeutics ..... Essential Biotechnology ..... Essential Medical .... Essentient .... Essex... Eta Devices ..... Eta-Gen .... Etegent Technologies ... E-Tek Dynamics ... Euclid Labs .... Euclises Pharmaceuticals ..... Eureka Therapeutics ..... Euthymics Bioscience ... EVapt .... Evelo Therapeutics .... Evena Medical ..... Ever Cat Fuels ... Evergen Biotechnologies ... Evergreen Solar ... Everspin Technologies .... Evestra .... Evident Technologies ... Evoke Pharma ..... Evolution Robotics ... Evolv .... Evolve BioSystems ....EWI .... Exact Sciences .... Exagen Diagnostics ... Excelimmune ... Excel Technology .... Excision BioTherapeutics ..... Exelixis ..... Exelixis Plant Sciences ... Exemplar Genetics .... Exo ..... Exogenesis ..... Exone .... Exosome Diagnostics ..... Exovita Biosciences .... ExploraMed NC4 ... Expression Analysis ....Exsulin ....Extreme Molding ... Extremity Innovations ... EyeGate Pharmaceuticals ... EyeNetra .... EyeTel

Fallbrook Technologies ... Famigo ... Faraday Pharmaceuticals .... Farodox Energy Storage ... FarSounder ... Far-Tech.... FastCAP Systems ... Fate Therapeutics ... Fathom .... Fe3 Medical .... FEI ... Femasys .... Femta Pharmaceuticals .... Ferrate Treatment Technologies ... Ferric Contrast ...... FerroKin BioSciences .... Feuz Manufacturing ... FGC Plasma Solutions ..... Fiber and Sensor .... Fiberight ... Fiber Materials ... Fibersense ... Fiberstar .... Bio-Ingredient Technologies Fibrocell Science ... FibroGen ... Filter Sensing Technologies ... Finally Light Bulb ..... Finch Therapeutics Group ..... FineLine Prototyping .... Finisar ... Fire Alarm Specialty Design ..... Firefly BioWorks ... Firefly Energy .... Firefly LED ... First Solar ... Fisker Automotive ... Five Prime Therapeutics .... Flex Biomedical ... Flexion Therapeutics ... Flextronics America .... Flexus Biosciences .... FLIR Systems .. FloDesign Wind Turbine ... FlowCardia ... FlowMedica .... FlowMetric .... Flow Metrix ... FluGen ... Fluidic Energy ... Fluidigm ... Fluid Innovation Group ... Fluidnet ... Fluidnet FluoroPharma ... Fog Pharma ..... Foghorn Therapeutics .... FokusLabs .... FoldRx Pharmaceuticals ... Follica ... Footnote .... Foresight Biotherapeutics .... Forest Devices .... Forge Therapeutics ..... F-Origin ... Forma Therapeutics ... Formlabs .... For-Robin ..... ForSight Vision5 .... Fortis Therapeutics ..... Forty Seven ..... Forum Pharmaceuticals ..... Forus Health ... Foster-Miller .... Foundation Medicine ... Fox Chase Chemical Diversity Center .... Fractal Antenna Systems ... Fractyl Labs ..... Freedom Meditech ... Free Flow Power ... Free Form Fibers .... Freenome ..... Frontier NanoSystems ..... FTL Solar ... FuelCell Energy ... Fuel Tech .. Fulcrum Therapeutics ..... Fulgent Therapeutics ..... Full Spectrum Genetics .... Furiex .... Fused Innocation. ... Fusion Coolant Systems

G1 Therapeutics ..... G3 .... Gadusol Laboratories (aka Seaceuticals) ..... Galderma .... Galectin Thera ..... Galenea ... Galena Biopharma .... Galera Therapeutics ..... Galil Medical ..... Galleon Pharmaceuticals ... GAM Enterprises .... GameSalad ... Gamma Medica Ideas ... Garland Technology ..... Garwood Medical Devices ..... GATR Technologies ..... G-Con .... Gecko Biomedical .... Gel Combs .... Gelesis ... Geltech ... Gema Diagnostics .... GEMFIRE .. Gemin X Pharmaceuticals ... Gemmus Pharma ... Gemneo Bioscience ..... Gemphire Therapeutics ...... Gemstone Biotherapeutics ..... Gen9 ... Genaera ... Genalyte ... Genapsys .... GenAudio .... Gene by Gene .... GeneCentric Diagnostics ... Genelabs Technologies ... Gene Logic ... Geneoscopy ..... General Compression ... General Pneumatics ..... Generation Bio ..... Generex Biotechnology ... Gene Security Network .... GeneSegues Therapeutics ..... GenesisLabs .... GeneSystems ... Genetesis .... Genetic Networks ..... Genetix Pharmaceuticals ... GeneTx Biotherapeutics ..... Geneu .... Genia Technologies .... GenMark Diagnostics .... Genoa Pharmaceuticals ..... Genocea Biosciences ... Genomatica ... Genome Profiling ... GenomeQuest ... Genomic Health ... Genomind .... Genoptix Medical Laboratory ... Genor ... Genprex .... Gen-Probe ... GenSpera .... GenTel BioSciences ... Gentris ... GenturaDx ...nbsp; GenVec ... GenWay Biotech ..... Genzyme .... Geocent .... Geocove ..... Geomagic ... GeoMed Analytical ... GeoVax Labs ... Geospiza ... Germfalcon ..... Geron ... Gevo ..... GI Dynamics ... GigOptix ... Gilead Sciences .... Giner . .. Ginkgo BioWorks .... Glauconix ..... Glaukos .... GlideLine Systems ... Gliknik ... Global Blood Therapeutics ...... Global Cancer Diagnostics ..... Global Positions ... Global Blood Therapeutics .... GlobeImmune .... Gloucester Pharmaceuticals ... Glowforge ..... GlucaGo ... GlycoFi ... GlycoMimetics .... GlyGenix ... Glyscend ..... GlySens ... GMZ Energy ... GnuBio .... Goddard Labs .... Goldfinch Bio ..... Good Start Genetics .... Gore Photonics ... Gossamer Bio ..... Gotham Biotech .... GPC-Rx ... gRadiant Research ... Gradiant .... GraftWorx ..... Grail ..... Graphene Energy ... Graphenix Development .... Graphic Surgery ... GraphLab (now Dato) .... Grassroots Biotechnology ... Greatbatch ... GrayBug ..... Graybug Vision ..... Great Basin Scientific ..... GreatGrow Maryland .... GreatPoint Energy ... Green & Grow .... GreenFuel Technologies .... Greenlight Biosciences .... Green Mountain Radio Research .... GreenSight Agronomics ..... Green Sulfcrete ..... GreenTech America ... Greenwich Geriatrics .... GridBridge .... Grid Therapeutics ..... Gritstone Oncology ..... GRO Biosciences ..... Group14 Technologies ..... Grove Instruments ... Grow Home Organics .... GSI Technology ... GT Advanced Technologies ... GTC Biotherapeutics ... G-Tech Medical .... GT Equipment .... GTI Diagnostics ... GT Medical Technologies ..... GTx .... Guardant Health .... Guided Surgery Solutions .... Guided Therapeutics .... .... Guided Therapy Systems ..... Gynesonics ..... G-Zero Therapeutics

2 Energy Now ...... H2O Score ..... H2Pump ... H2Sonics .... H3 Biomedicine ... HNC Software ... Halozyme ... Hana Biosciences .... Hansen Energy and Environmental .... Hansen Medical ... Haplogen Genomics ..... Harbor Technologies .. Hardcore Computer ... HarkerBio .... Harmony Enterprises .... Harpoon Medical .... Harvard Apparatus Regenerative Technology .... Harrisvaccines .... Harvard Bioscience ... Harvest Automation .... Harvest Power ... Harvest Technologies .... Healionics .. Health Diagnostics Laboratories .... HealthMyne .... Healthtronics .... Hearforward ... Heartland Robotics .... HeartWare International ... Heat Biologics .... ... HeatGenie ... Helicos BioSciences ... Helion Energy .... Heliovolt ... Helius Medical Technologies ..... Helix Therapeutics ... Helomics (formerly Precision Therapeutics) ..... Hemadvance ..... HemaQuest Pharmaceuticals ... Hemarrest ... Hemera Biosciences .... Hemispherx Biopharma .... HemoGenyx .... HemoSonics ..... Hemostasis ... Hennepin Life Sciences .... Hepregen ... Heraeus Medical Components .... Herley Industries ... Hermes Biosciences ... HexaTech .... Hexfuel .... Hibernaid .... High Impact Environmental .... High Performance Technologies ... High Point Pharmaceuticals ..... Histogen .... HighRes Biosolutions .... Histogenics ... HistoRx ... HistoSonics .... HJM Precision ..... HocusLocus ..... Hoku Scientific ... Holaira .... Hollingsworth & Vose .... Hollis-Eden Pharmaceuticals ... Holomni .... Homology Medicine ..... Honeycomb Batteries .... Hontek ... Hoopers Island Oyster Aquaculture ... Hoppe Tool .... Hsiri Therapeutics ..... HTG Molecular ..... HTSS ... Humacyte ... Humanetics ..... Human Genome Sciences ... Human Metabolome Technologies .... HuTerra .... Huya Bioscience International .... Hybritech ..... Hybrivet .... HYCOR Biomedical ... Hydra Biosciences ... HydroCision ... Hydrogen Safety ... HydroLogic Industries .... Hygeia Therapeutics ... HyperBranch Medical Technologies ... Hyperion Therapeutics ... HyperMed ... HYPRES .. Hy-SyEnce ... HyTrust

IAP ... IBC Advanced .... iBiquity Digital ..... Ibis .... Iblogix .... IBT Laboratories ... Icagen .... Icardiac.... Ichor Medical Systems .... Iconic Therapeutics ..... Icos.... ICX.... Idaho.... Ideal Converters ... Ideapaint.... Ideaya Biosciences ..... Idera Pharmaceuticals ..... ID Genomics .... Idevices ... IDx ..... iFirst Medical Technologies ...... IFM Therapeutics ..... Igenica Biotherapeutics .... Ignyta.... Ii-IV .... Ikaria... Ikonisys... Illinois Superconductor.... Illumigen.... Illumina.... Illuminating Diagnostics ..... Illuminoss.... Illumitex.... Imagen Energy .... Imagevision.... Imaging Biometrics... Imagineoptix ... Imago Instruments... Imanis Life... Imbed Biosciences... Imetalx... Immco... Immersion... Immtech... Immucell .... Immucor .... Immune... ... Immune... Immune Pharma .... Immunetics... Immunex... Immunexcite... Immuneworks... Immunexpress ..... Immunicon... ImmunoCellular Thera .... ImmunoChemistry Technologies ..... Immunocore... Immunogen... Immunome ..... Immunomedics..... Immunomic Therapeutics ..... Immunophotonics ... Immurx... .... Immusant... Immusoft ..... Impact Biomedicines .... Impact Science... Impel Neuropharma... Imperium Renewables... Impinj... Implant Sciences... Impossible Foods .... Imprimis Pharmaceuticals .... Imprint Energy .... Impulse Monitoring ... Imricor Medical Systems ..... Imris ..... Imthera... I-nalysis ... INCELL .... Incelldx ..... Incitor (now XF Technologies) .... Incodema3D ..... Incontrol Research... InCube Labs ..... Incyte ....Incytu... Indalo Therapeutics ..... Indiana Nanotech... Indi Molecular ... Industrial Heat ..... Industrial Perception... Inentec ... InfaCare Pharmaceutical .... Infarct Reduction Technologies .... Infinera... ... Infinia... Infinity... Infinium .... Inform Genomics... Infoscitex... Inframat... Infraredx... Infrascan... Inf Robotics ... Infusion Medical ... Ingeneus... Ingeneron ..... Inhibitex... Inhibkase Therapeutics .... INI Power... Inland Labs ..... Inmobly .... InnAVasc Medical .... Inneroptic... Innerpulse... Innocrin Pharmaceuticals ..... Innography... ... Innopad... Innotec ..... Innovalight... Innovari Energy Design Microplate Scientific... pulmonary solutions.... silicon... Innovate Biopharmaceuticals ..... Innovative Spinal... Innovative... Innoventiontech ... Innovention (now Ccardiorobotics) ... Innovative Trauma or... Innovolt ... Innowave... ... ... Innoviva ... Innov-x... Inocucor ..... Inorganic Specialists... Inotek... Ino .... Inova Labs Biomedical... Inovio... Inovise Medical ..... Inozyme Pharmaceuticals ..... Inphase... ... Inphi... Inpria ..... Inscripta ..... Insert MRI... Insight... ..Insite Vision...... Insitu... InSitu Biologics ..... Insmed... Inspired Solar Systems ... Inspire... Insulet Labs ... Intact Vascular... Intaglio... Intalio ... Intarcia Therapeutics ... Integenx... Integra Group Diagnostics... Integral Molecular ..... Integrated BioTherapeutics .... Integrated Diagnostics .... Integrated Diagnostics InDi .... Integrated DNA Technologies ..... Integrated Fuel... ... Integration Associates... Intelect Medical Intelleflex ... Intellia Therapeutics ..... Intellicyt Automation Bio-systems ... Intelligent Devices .... Intelligent Epitaxy Technology ..... Intellimedix ..... Intelliphage.... Intellirad Control... .Intellisense .... Intelomed ....Inter-4... Interactive Supercomputing ... Interdigital Interlace .... Intermagnetics General ...Intermolecular ... Intermune.... International Stem Cell ... Interrad Medical ..... IntersectENT .... Intersense... Intersystems ... Intervalve.... Intevac.... Intra-Cellular Therapies ..... Intralase ...... Intralytix .... Intrexon ..... Intrinsity.... Introgen.... ... Intuitive Biosciences .... Intuitive Genomics ..... Intuitive Surgical.... Invenra .... Invensense .... Inventev ..... Inverness Innovations.... Invirsa ..... Invertix.... Invictus.... Inview Technology.... Inviragen.... Invisage Technologies .... ....InvisionHeart .... Invision Medical .... Invitae.... Invitrogen.... ...Invivosciences.... Invivo Therapeutics= Holdings .... Invuity.... Inx Medical.... IoGyn .... Iomai.... ... Iomed.... IOmet Pharma ..... Ion America Optics..... Ionic Materials ..... Ion Torrent.... Iovance Biotherapeutics ..... Iovation.... Iowa Thin Film.... Ipierian.... IPG Photonics.... ... Iquum ...Irhythm... iRobot... Iroko...Ironbridge.... ... Ironwood.... ... .... Irvine Sensors... .... biopolymer . .... Ischemia Care.... iSee ..... iSIGHT Partners ..... Isis.... Island Ddata.... Isogenis.... Isomark.... IsoPlexis .... Isoray.... Isothermal.... Isthmus Biosciences ..... IstoTechnologies.... itaconix.... I-Therapeutix..... Itherxm Pharmaceuticals.... Itraumacare... .. Itseez ..... Itzbig ..... Iwalk

Jade Therapeutics ..... J&Y ... Janssen Biotech .... Janus Biotherapuetics ... Javelin Pharmaceuticals ... Javelin Semiconductor ... JDP Therapeutics ..... Jennerex ... Jnana Therapeutics ..... Joule Biotechnologies .... Jounce Therapeutics .... Joyent .... Joylux .... Juno Therapeutics ..... Just Biotherapeutics

K2M .... K2 Therapeutics .... KAER Biotherapeutics .... Kala Pharmaceuticals ... Kallyope ..... KaloBios Pharmaceuticals ..... >Kalocyte .... Kalon Biotherapeutics ..... KalVista Pharmaceuticals .... Karius ..... Karyopharm Therapeutics ... Kateeva ..... Kayo Technology ..... KaZaK ... KC BioMediX ... KCI .... KDH Defense Systems ... Keithley Instrument ... Kelyniam ... Kenall Manufacturing ..... Kensey-Nash ... Kent Displays ... Kentucky BioProcessing .... KeraNetics .... Kezar Life Sciences ..... KeyW .... Kilawatt Technologies ... Kindara .... KinDex ... KindHeart ..... KineMed .... Kinestral Technologies ..... Kineta ... Kinetic Concepts .... Kinex Pharmaceuticals .... Kingbright .... Kior ..... Kips Bay Medical ... Kite Pharma ..... Kitware ... Kiva Systems ... KLD Energy Technologies .... Klotho Therapeutics .... KMel Robotics .... Knightscope ..... Knome ... Knopp Neurosciences .... KNOW Bio ..... KnuEdge .... Kodiak Sciences .... Kolltan Pharmaceuticals ... Komoku ... Kona Medical .... Konarka ... Koning ... Kopin .. KOR Electronics ... Koronis Pharmaceuticals ... Kosan Biosciences ... Kosmetikos .... Kovio ... KPI Therapeutics (from Kineta)... Kraig Biocraft ..... Kratos Defense & Security Solutions .... Kronos Advanced Technologies ... Krystal Biotech .... KSE ... KSQ Therapeutics ..... Kultevat ..... Kura Oncology .... Kumu Networks .... KVH .. Kylin Therapeutics ... Kyma ....Kymera Therapeutics ..... Kymeta ... Kyn Therapeutics .... Kyocera Solar .... Kypha ..... Kyras Therapeutics ..... Kyron Clinical Imaging .... Kytopen

LAAMScience ... LaBelle Associates ..... LabNow ...Laborie Medical Technologies ... Labrys Biologics ... Lactic Solutions ..... Laguna Pharmaceuticals (formerly ChanRx) ..... La Jolla Pharmaceutical ... Lake Shore Cryotronics .... Landec .... Landos Biopharma .... Lantern Pharma ..... Lantheus ... Lantos Technologies ... Lariat Biosciences .... Laser Design .... Lasergen ..... LaserMax ..... LaserMotive ... Laser Tissue Welding .... Lattice Biologics ..... Lattice Biotech .... Lawrie ... Lazarus Effect ..... LDR Holding ..... Lead Therapeutics ... LeafBio .... LeCroy ... LED Lighting Fixtures ... Lehigh Technologies .... Leica Microsystems ..... LetoSolutions .... Lexicon Genetics ... Lexicon Pharmaceuticals ... Leyden Energy ... Libra BioSciences .... LifeCell ... LifeGen Technologies ... Life Image ... LifeMine Therapeutics .... LifeSprout .... Life Technologies .... Ligand Pharmaceuticals ....Ligon Discovery ... Lightpointe ... Light Sciences Oncology ... LightWorks Optics .... Lilliputian Systems .... Lily Robotics ..... Linares Management Associates .. Lingotek ... Lionano .... Lion Biotechnologies ..... Lipocine .... LipoScience ... Liquid Biotech ..... Liquidia Technologies ... Liquid Light ... Liquid Metal Battery ... LiquidPiston ... Liquid Robotics ... Liquid X Printed Metals .... LiQuifix ... Lithium Technology ... LiveData ... . LiveLeaf Bioscience .... Locus Biosciences .... Lodo Therapeutics .... Logical Therapeutics ... LogicBio Therapeutics ..... Logos Tech ... Lohocla Research ..... Lombard Medical ..... Longeveron ..... LonoCloud ..... Lookingglass ..... Loon Medical ..... Lotus Tissue Repair ... Loxo Oncology ... LPath Thera .... Lq3 Pharmaceuticals .... LS9 ... Luca Technologies .... Lucerno Dynamics .... Lucidux ... Lucigen .... LumaSense Technologies .... Lumena Pharmaceuticals .... Lumen Bioscience .... Lumencor ... Lumense .... Lumera ... Lumicell Diagnostics ... Luminary Micro ... Luminex .... Luminus Devices ... Lumisyn ..... Lumitex ... LumiThera .... Lumos Pharma .... Luna Innovations ... Luna Technologies ... Lung Therapeutics .... Lutonix ... Luxtera ... Lycera ... LyGenesis ..... Lyncean ..... Lynntech ... Lynx Biosciences ... Lysosomal Therapeutics .... Lytro Therapeutics

M3 Biotechnology .... MabVax .... MacAulay-Brown ..... Macrochem ... MacroFab ..... Macrogenics ... Macrolide Pharma ..... Macrophage Therapeutics .... Madison Vaccines .... Madrigal Pharmaceuticals ..... MagBioSense ..... Magenta Therapeutics ..... Magic Leap ..... MagneMotion ... Magnesium Development ..... Magnetek ... Magnolia Medical Technologies .... Magnolia Optical Technologies ... Magnolia Solar ... Mainstay Medical International ...... Mainstream Engineering ... Major Pharmaceuticals .... Mako Surgical ... Manhattan Scientifics ..... Mantra Bio ..... MapInfo ...MAP Pharmaceuticals ... Mapp Biopharmaceuticals .... Marathon Pharmaceuticals ..... Marcadia Biotech ... Marina Biotech ... Marinus Pharmaceuticals ... Maritime Applied Physics .... Marrone Bio Innovations .... Martek Biosciences ... Mascoma ... Mashery ... Mason Box ... Masten Space Systems ... Masterson Industries .... Mast Therapeutics (formerly ADVENTRX) .... Material Sciences ... Material Technologies ... MathStar ... Mati Therapeutics .... Matouk Textiles ... Matritech ... Matrix Product Development .....Matrix Research .... Matrix Sensors ... Maverick Therapeutics .... MAX BioPharma ... MaxCyte ...... Maxdem ... Maxpower ... Maxygen .... MBio Diagnostics .... MC10 .... MCube .... M Cubed Technologies .... MD Biosciences ..... MDSolarSciences ... Mebias Discovery ..... Mechanical Technology ... Mechanology ... Medafor ... Medarex ... MediBeacon .... Medicago USA .... Medical21 ..... Medical Cyberworlds .... Medical Device Logistics ... MedicaMetrix... Medgenics ..... MediciNova ..... Medicool Technologies .... MedImmune .. Medina Medical .... Mediomics .... Medior Therapeutics .... Medis ... MEDITE Group .... Medivation ... Mednology Solutions .... Medrobotics ... MedShape .... MedSocket (formerly 1CDS) ...... Medsphere Systems ..... MedTel ..... MEI Pharma ..... Meka .... MELA Sciences .... Melinta Therapeutics .... Melior Discovery .... Memjet ...Memry ... Memsic ... MEMS Optical...Menlo Therapeutics ..... MER ... Mercator Therapeutics ... Mercury Computer Systems .... Merganser Biotech .... Merge Technologies ... MeriaGTx ..... Meridian Bioscience ... Meritage Pharma ..... Merkatum ... Merrimack Pharmaceuticals ... Meryx .... Mersana Therapeutics ... Mesa Photonics ... Mesocopic Devices ... Metabasis ... Metabiota .... Metabolic Solutions Development .... Metabolex .... Metabolix ... MetaCarta ... Metacrine .... Metactive Medical ..... Metal Oxygen Separation Technologies ... Metamark Genetics ... MetaModix ... Metavention ..... Metompkin Seafood .... MetroLaser ... MGC Diagnostics ... Misaole .... Micell Technologies ... Michelman ... Micracor .... Micrel ... MicroCoating ... Micracor .... Microbe Detectives ... Microbia ... Microbot Medical ... Microfluidics International (Microbia) ... MicroGreen Polymers .... MicroIslet ... Microlin Bio .... MicroMask ... Micronics ... MicroOptical (New Mexico)... MicroOptical (Massachusetts) ... MicroOptx ..... MicroPower Technologies ... MICROrganic Technologies .... MicrowSat Systems .... Microscopy Innovations ..... Microstaq ... MicroTransponder ..... Microvision ... MicuRx Pharmaceuticals .... Midori Renewables ..... Mid Valley Industries ... Millendo Therapeutics (born as Attercor) ..... Million Concepts ..... Miltec .... MiMedx Group .... MimiVax .... Minerva Biotechnologies ... Minerva Neurosciences .... Minerva Surgical .... Minimally Invasive Devices .... Minnesota Thermal Science ..... Minnetronix ... MIOX ..... Mirador Biomedical ... Mira Dx ... MiRagen Therapeutics ..... Miramar Labs .... Mirati Therapeutics ..... Mirimus ... Mirina ... Mirna Therapeutics.... Miromatrix Medical ... Mirus Bio ... Mission Research ... Mississippi Polymer ... Mithridion ... Mitochon Pharmaceuticals ..... Mnemosyne Pharmaceuticals ... Mobile Robots ... Mobius Therapeutics ..... Moderna Therapeutics .... Modern Meadow .... Modern Technology Solutions .... Moduline Systems .... Modumetal ..... MOgene Green Chemicals .... Molecular Biometrics ... Mohawk Innovative Technology ..... Molecular Detection ... Molecular Diagnostics .... Molecular Imprints ... Molecular Insight Pharmaceuticals ... MolecularMD ... Molecular Sensing ... Molecular Templates .... Moleculin Biotech ..... Molten Metal .. MoMelan Technologies ... Momenta Pharmaceuticals ... Monebo ... Monogram Biosciences .... Monteris Medical ..... Morphic Therapeutics ..... Morphormics ... Morphotek ... Morris Innovative Research ... Mortara Instrument ... MortaSecurity .... Motricity ... Motus Therapeutics .... Mound Laser & Photonics Center ..... Movia Robotics ..... Moximed .... MPP Group ... MPSP ... MSNW .... Mudawar Thermal Systems ..... Munksjo Paper ... Muons ... Muse bio .... Myco Technology .... Myocor ... MyoKardia ... Myomo ... Myonexus Therapeutic ..... Myovant Sciences ..... Myriad Genetics ... Myriant Technologies ... Mystic Pharmaceuticals

N12 Technologies ... (N30 Pharmaceuticals) now Nivalis Thera .... NABsys ... Nalas Engineering .... NanOasis Technologies ... NanoBio ... Nanobiosym ... Nano-C ... NanoCellect (formerly NanoSort) ..... Nanocomp Technologies ... NanoCoolers ... Nanocopoeia ... NanoCor Therapeutics ...Nanodynamics (Buffalo) ... Nano DX ..... Nanodynamics (NYC)... NanoeXa .... Nanofiber Solutions ... Nanogen ... NanoGram .... nanoGriptech ..... NanoH2O ... Nanohmics ... NanoLab ... NanoLite Systems ... NanoLogix ... NanoLumens ..... Nanomaterials Research ... NanoMatrix ... NanoMedex ... NanoMedicalSystems ... NanoMedical Systems .. Nanomix ... nanoMR ..... Nanophase Technologies ... NanoPhotonica ... Nanopore Diagnostics ..... Nanoptek ... nanoRETE .... Nanoscale Components ... Nanoscale Materials ... Nanosolar ... Nanosonic ... Nanospectra Biosciences .... Nanosphere ... NanoSteel ... Nanostim .... NanoString Technologies .... Nanosys ... NanoSystems ... Nano Tailor ... Nanotek Instruments ..... Nano-Terra ... Nanotherapeutics ..... NanoTune Technologies ... Nanova .... Nanovation Technologies ... NanoVault Medical .... NanoViricides ... NanoVision Diagnostics .... Nantero ... Napo Pharmaceuticals ... NantKwest ..... Narus Biotechnologies ..... Nascentric ... Nastech Pharmaceutical ... Natera .... National Technical Systems ..... Natural Molecular Testing ..... NaturalNano ... Nature's First ..... Natus Medical ... Naverus ... Navidea Biopharmaceuticals ... Navini Networks ... Navire Pharmaceuticals .... Navitor Pharmaceuticals .... Navmar Applied Sciences ... NBD Nanotechnologies ....NCD Technologies .... nContact Surgical ... Neah Power ... Near Infinity .... Neato Robotics ... Nektar Therapeutics ... Nekton Research .... NemaMetrix .... NeoChord ... Neogen .... Neograft ..... NeoLight ..... Neon Therapeutics .... NeoPhotonics ... Neoprobe ... Neos Therapeutics ..... NeoSync ..... Neothetics .... Neotron ... NephroGenex .... Nereus Pharmaceuticals ... Nest .... Netezza ... NetLogics Microsystems... Netspeed Systems ...... Net Watch Solutions ..... NetworkFab ... NeurAccel Biosciences ... Neurala .... Neural Analytics .... Neuralstem .... Neuraptive Therapeutics ..... Neuro Amp .... Neurobiological Technologies ... NeuroChaos Solutions .... Neurocrine Biosciences ... NeuroDx Development ... NeuroEM .... Neurodyne Medical ... Neurofluidics ....Neurogastrx .... Neurogen ... NeurogesX ... Neurognostics .. NeuroHabilitation .... NeuroLogica .... NeuroLutions ..... NeuroMap ... Neuro Kinetics .... NeuroMetrix... Neurona Therapeutics .... Neuronetics . Neuronex .. NeuroPace ... NeuroPhage Pharmaceuticals ... Neuron Systems ... NeuroPointDX ..... Neuroptix ... Neuroscience .... NeuroTek .... Neurotrack .... NeuroTronik .... Neurotrope ..... Neurovance ... NeuroVigil ... Neurovascular Diagnostics ..... NeuroVision Imaging .... NeuroVista .... NeuroVive .... NeuWave Medical ...Nevro ... New Dominion Enterprises ..... NewLeaf Symbiotics .... NewLink Genetics .... Newlink genetics england ... biolabs ... new era technology ... New Haven Pharmaceuticals ... Nexant ...Nexbio ... NexImmune .... NexPlanar .... NextCODE Health .... NextCure ..... Nextio .... NEXTracker ....Nextreme Thermal Solutions ... NextStep Robotics ..... Nexus Biosystems ..... NG1 Technologies .... NGM Biopharmaceuticals .... Nico ..... Night Vision ... Nimblegen Systems ... Nimble Storage .... Nimbus Discovery ... Nimbus Therapeutic ..... Ninepoint ...Niowave ... NIRvana Sciences .... Nitero.... Nitric Biotherapeutics ....Nitricgen ... Nitride Solutions .... Nitrogenics ..... Nitromed ...Nitronex ... Nivalis Therapeutics formerly N30 Thera ..... NKT Therapeutics ... Nlight ... NMT Medical .... Noah Technologies .... Noble Fiber ... Nohla Therapeutics .... Noivatone .... Nok Nok Labs .... Nomadics .... NONA Composites .... Noninvasix .... Nonvolatile Electronics .... Nora Therapeutics .... Norian ... NorMedix ..... Normoxys .... Norse .... Northeast Photosciences ... Northstar Medical Radioisotopes .... Northstar Photonics... Northwest Biotherapeutics .. Norwich Technologies .... Nostopharma .... Notice Ttechnologies ... .Novacea ... Novalar Pharmaceuticals ... Novalux ... Novan Therapeutics .... NovaScan ... Nova Synthetix .... Novatek ... NovaTorque ... NovaTract Surgical ... Novavax .... Novazyme Pharmaceuticals ..... Novecon Technologies ... Novella Clinical .... Novelos Pharmaceuticals ... Novelos Therapeutics ... Noveome Biotherapeutic ..... Novian Health .... Novira Therapeutics ... Novocell ... Novogy ... Novomer ... Novophage ... Novo Sol-u-tions MD .... Novosource ... Novozymes .... Novus Biologicals .... Noxilizer ... Nox Technologies ... NP Photonics ... NPS Pharma ..... NRGindependence ..... NSS Labs ..... Nucelis .... Nuclea Bioechnologies ... Nufern .... NuGEN Technologies ..... NuMat Technologies ..... NuMedii .... NumereX .... NUMiX Materials ..... NuPathe .... Nurel (now PeriphaGen) .... Nuron Biotech ... Nutrabiotix ... Nutrient Recovery and Upcycling .... NuVant ... NuVascular Technologies .... Nuve ..... Nuventix ... Nuvera Biosciences ... Nuvera Fuel Cells.. . Nuvotronics ..... Nuvox Pharma ..... Nu Waves ..... NxThera ... Nvision Biomedical Technologies ..... NZ Applied Technologies

Oak-Mitsui .... Oasys ... ObjectVideo ... Obsidian Therapeutics ..... OBS Medical ... Ocarina Networks ... Ocata Thera ... Occipital .... Ocean Power Technologies ... Ocean Renewable Power .... Ocera Thera .... OCI ... Ocugen ..... Ocular Therapeutix .... Oculeve ... Oculus ... Oddpost ... Odyssey Systems Consulting Group ... Oil Chem Technologies ... OLEDWorks .... Omeros ... OmniGene Bioproducts ... OmniGuide ... OmniLytics ... Omniox ..... OmniSonics Medical Technologies ... Omnis PharmaRebiotix .... Omni Water Solutions ... Onboard Dynamics .... ONCE Innovations ..... OnChip Power .... Oncobiologics ..... Oncogenex ... Oncolmmune ..... Oncolinx .... Oncolix ..... Oncolytics Biotech ... OncoMed Pharmaceuticals .... OncoNano Medicine .... Onconova Therapeutics ...Oncoscope ... OnCore Biopharma ..... OncoResponse ..... Oncorus ..... OncoSec Medical .... OncoTartis ...... Oncothyreon ... Oncovista Innovative Therapies ..... Onduo ..... One Resonance Sensors .... Onko Solutions .... ONL Therapeutics .... On-Q-ity .... Onspira Therapeutics .... On Target Laboratories .... Ontela ..... On-X Life Technologies .... Onyx Pharmaceuticals ... Oorja Protonics .... Open Algae ... Open Monoclonal Technology ..... Open Silicon ... OpenWater Power .... Opertech Bio ..... Opexa Therapeutics ... OpGen ... OPNET Technologies ... Opsonix .... OptTek Systems ... Optelecom ...Optelecom-NKF ... Optherion ... Optical Concepts .. Optigain .. Optimal Technologies ... Optimus Technologies .... OptiNose .... Optivision ... Optofluidics ... OptoLum ..... Optonicus .... Opto Technology ... Optomec .... OPX Biotech ... Oragenics .... OraMerix ... Orasi Medical ... OraSure Technologies .... Orbital Technologies ... Orbotix .... Orchard Therapeutics ..... Orchid Cellmark ... Oregon Iron Works .... Orexigen Therapeutics ... Organic Research .... Organogenesis ... Organovo .. ORIC Pharmaceuticals ..... Oricula Therapeutics .... Origin Medsystems ..... OriginOil ... Orion Energy Systems ... Orion Genomics ... Ormet Circuits ... Orologic... OrphoMed ..... Ortel ... OrthoAccel Technologies ... Ortho Kinematics .... Oryx Technology ...Oscient Pharamceuticals ...Oscilla Power .... Osiris Therapeutics ... OSI Pharmaceuticals ... Oso Biopharmaceuticals Manufacturing .... Osprey Medical .... Ossianix ... Ostendo Technologies ... Osteotech ... Osterhout Design Group .... OtoNexus Medical Technologies .... Otonomy .... OtoSense .... Ottomatika .... Outset Medical .... OvaScience ... >Ovid Therapeutics ..... Oxford Performance Materials ... Oxis International .... Oxygen Biotherapeutics

P3I ... Pace Packaging .... Pacific Biosciences .... Padlock Therapeutics .... Pain Therapeutics ... PaizaBio .... Palantir Technologies .... Palleon Pharmaceuticals .... Palmaz Scientific ..... Palmer Labs ... Paloma Pharmaceuticals ... Panacea Solutions .... Panacos ... Pandion ..... Pandromics ..... Pan Genome Systems .... Panomics ..... PanTheryx .... Paper Battery .... PapGene .... Paradigm Diagnostics .... Paradigm Sensors ... Paradromics ..... ParaGen Technologies ..... Paragon Dynamics ... Paragonix Technologies .... Parasol Therapeutics ... Paratek Pharmaceuticals .... Parexel International .... Parion Sciences ... ParkerVision .... Partner Therapeutics ..... Partpic .... Passport Systems ... Pasteuria Bioscience ... Pathfinder ... PathoGenetix ... PathoVax ..... Pathway Genomics .... PatientStream ... PatientWise ... Patton Medical Devices ... Patton Surgical .... Pavilion Technologies ... Pax Streamline ... PaxVax ... PDI Therapeutics ..... PDL BioPharma ... Pearl Therapeutics ... Pear Therapeutics ..... PECA Labs .... Pediatric Bioscience .... Peerless Technologies .... Pegasus Sustainability Solutions .... Pelican Products ..... Pellion Tech ... Peloton Therapeutics ..... Peninsula Pharmaceuticals ..... PennAlt Organics ..... Penumbra ..... PeproMene Bio .... Peptimed ... Peptilogics .... Peptimmune ... Perceptive Navigation ..... Perceptive Sciences ... Perceptron .... PercipEnz Technologies ... Peregrine Semiconductor .... PeriphaGen .... Permeon Biologics ... Perosphere .... Perscitus Biosciences ... Perseon ..... Persimmon Technologies .... PersonalBee ... Personalis ...... Personal Genome Diagnostics .... Pervasis Therapeutics ... Pervasive .... Petra Pharma ..... Pfenex ... Pharmacyclics .... PharmaJet .... PharmAkea Therapeutics .... Pharmasset ... PharmAthene ... PharmatrophiX .... PhaseBio Pharmaceuticals .... Phase Bioscience ... PhaseRx .... Phigenix ..... Phoenix Biotechnology .... Phoenix Nuclear Labs ... Phoenix Science .. Phononic Devices ... Photobit ... Photolitec ..... PhotoMedex ... Photonics Innovations ... Photon-X .... PhotoSonix Medical .... PhotoThera ... Photronics ... Phoundry Pharmaceuticals .... Phrixus Pharmaceuticals ..... Phurnace Software ... Phylonix .... Phylos Bioscience ..... Physcient .... Physical Optics... Physical Sciences ... PhysioGenix ... PhysioSonics ... PhytoTech ... Picolight .... Picometrix ... Piedmont Biofuels .... Pieris Pharmaceuticals ..... Pika Energy ... Pilus Energy .... Pinger ... Pinnacle Technology ... Pioneer Surgical Technology .... Pionyr Immunotherapeutics ..... Pixelligent .... Pixel Optics .. Pixim ... Pixtronix ... Plakous Therapeutics ..... Planar Energy ... Planar Systems ... Planet Labs .... Plano Microwave ..... Plasan ... PlasmaTech Biopharmaceuticals .... Platelet BioGenesis .... Platypus ... Play-i .... PLC Medical Systems ... Plextronics ... Plexxikon ... Pliant Therapeutics .... Plug Power ... Pluromed ... PLx Pharma ..... PLX Technology .... PMT .... PMV Pharmaceuticals .... PneumRx ..... Point Source .... Polarean ..... Polatis .... Polychromix ... Polyera ... PolyMedica ... PolyMedix ... Polymer Technology Systems ... Polynoma ..... PolyNova .... PolyPlus ... PolyRemedy ... Polysciences ... Polystor ... Portola Pharmaceuticals ... Possis Medical ... Pothole Pros ... PowerGenix ... Powerlight ... Power Precise Solutions ... PowerVision ... Pozen ... Prairie Technologies ..... Pranalytica ... Praxis Biotechnology ..... Precision Biopsy ... Precision BioSciences .... Precision for Medicine .... Precision Genome Engineering .... Precision Ocular Metrology ..... Precision Optics ... Precision Therapeutics (now Helomics) .... Precision Virologics .... Predictive Biosciences ... Pregmama ..... Presage Biosciences ... Presidio Pharmaceuticals .... Pressure BioSciences ... PreTalen ..... Prevail Therapeutics ..... Preventice ..... Prevention Pharmaceuticals .... Prieto Battery ..... Primary Data ..... Primera Biosciences ... Primordial .... Primorigen Biosciences ... Primus Power .... Princeton Satellite Systems ..... Principia Biopharma .... Prism Solar Technologies .... Procept BioRobotics ..... ProCertus BioPharm ... Processa Pharmaceuticals ..... Proclara Biosciences (formerly NeuroPhage Pharmaceuticals) .... Procyrion .... Profectus BioSciences . .. Progenics Pharmaceuticals ... Progenity .... Prologic ... Promedior ... Promega ..... Promentis .... Pronutria ..... Propagenix ..... Propeller Health .... Propulsive Wing .... ProstaGene .... Protagonist Therapeutics .... Protein Foundry ..... Protein Sciences ... ProteinSimple (formerly Cell Biosciences) .... Proteon Therapeutics ... Proteostasis Therapeutics ... Proteotech ... Proteus Biomedical ... Proteus Digital Health .... Protez Pharmaceuticals .... Prothena .... ProThera Biologics ... Proto Labs ... Proton Energy Systems ...Protonex .. Prototype Productions .Provagen ... Provenance Biopharmaceuticals ... Provention Bio .... Proventys ... Provista Diagnostics .... Pryor Medical Devices ..... PsiKick ..... pSivida ... PTC Therapeutics .... Pulmatrix ... Pulmotect ..... Pulse Electronics .... PulseTherapeutics .... Puma Biotechnology ..... PUR Biologics ..... Pure Bioscience .... Purfresh ... Purillume ..... Pursuit Vascular ... PurThread .... PvP Biologics

Qcept Technologies .... Qcue .... QD Vision ... QED ... qFuzion ..... Qioptiq ... QM Power ... QPixel ... QR Pharma ... QSpex .... Qteros ... QuaDPharma .... Quadra-Aerrow International ... Quadraspec ... Quad Technologies .... Qualcomm ... QualityMetric ... Qualtech Systems .... Qualtré ... Quanterix ... QuantRx Biomedical .... Quanttus .... QuantTera .... Quantum Circuits ..... Quantum Epitaxial Designs ... Quantum Fuel Systems... Quantum Logic Devices ... Quantum Materials .... QuantumSphere .... Quark Biotech ... Quark Pharmaceuticals ... Quentis Therapeutics ..... Quick–Med Technologies .... Quid ..... Quidel ... Quincy Bioscience ... Quintessence Biosciences ... Quorum Systems

Radant Technologies ... Radiabeam Technologies ... Radiance Technologies .... Radiant Photonics...Radiation Monitoring Devices ... RadioMedix ... Radius Health .... Rafagen ... Rainbow Organic Farms ... RainDance Technologies ... RainStorm ... Rain Water Solutions ... Rallybio ..... Raland Therapeutics .... RaNA Therapeutic ... RAN Biotechnologies .... Range Fuels ... Rapamycin Holdings ..... RaPharmaceuticals ... Rapid Diagnostek ... Rapid Micro Biosystems ... Rapiscan ... RareCyte ..... Raser Technologies .... Raydiance ... Raymond .... Raze Therapeutics .... RE2 .... Ready Robotics ..... Reata Pharmaceuticals .... Rebellion Photonics .... Rebion ..... Rebiotix .... Receptor Logic ... Receptos ..... Recodagen ... Recombinetics ... ReconRobotics .. Recovery Engineering ..... Recro Pharma .... Recursion .... Redox Power Systems .... Red Rock Biofuels .... Redwood Robotics .... RedZone Robotics .... RefleXion Medical .... Refuge Biotechnologies .... Regado Biosciences ... ReGear Life Sciences ..... ReGen Biologics ... Regenerative Medical Solutions ..... Regenerative Sciences ... Regenxbio .... Regulus Therapeutics ... Rehabtics .... Relay Therapeutics ..... ReliantHeart .... ReliefBand Technologies ..... Relievant Medsystems ..... Relypsa .... Remedium Technologies ... RemoteReality .... Rempex Pharmaceuticals .... Renaissance Services ..... Renegade Materials .... Reneo Pharmaceuticals ..... Renewable Alternatives ... Renewable Energy Group .... Renmatix ..... RenovoDerm .... Renovion .... Renovis ... Rentech ... Replidyne ... Repligen .. Replimune Group .... Research Frontiers .. Resolve Therapeutics ... Resolvyx Pharmaceuticals ... Resonetics ..... Respicardia ... Respira Therapeutics .... Response Genetics ... Restoration Robotics .....Restore Medical ... Retectix ..... Retek ...Rethink Robotics ... Retriever Technology .... RetroSense Therapeutics ..... Reva Medical ... Revance Therapeutics Pharmaceutical .... Revegen ... ReVision Optics .... ReVision Therapeutics .... Revitope Oncology ..... ReVivo Medical .... RevMedx .... ReVolt Tech ... Revolution Medicines .... ReWalk Robotics (Israel) .... Rexahn Pharmaceuticals ... Rex Computing ..... RF Code ... RFMicron .. RFS Pharma ..... RF Surgical. .... Rgenix .... Rhenium Alloys .. Rheos Medicines ..... Rheumco .... Rhevision ... Rho ... Rhythm Pharmaceuticals ... Rhythmia Medical ... RiboNova ...... Rib-X Pharmaceuticals ... Rice Technology ..... Ridgetop Group ... Rigel Pharmaceuticals .... RightEye ..... RightHand Robotics .... Rinat Pharmaceuticals .... Rinovum Women’s Health ..... Rio Grande Neurosciences ..... RipCode ... River Vision Development ..... Rive Technology ... RJA Dispersions ... R.L. Phillips ... RMH Sciences ... Robb Surgical Devices .... Robopsy ... Robotic FX ... Robotics VISION Technologies ..... Robotic Technology ... Rocket Pharmaceuticals .... Rockwell Medical ..... Rocky Research .... Rodin Therapeutics ... Roka Bioscience ..... RoosterBio .... Rosina Food Products .... Ross Valve ..... Rotational Medical .... RotoMetrics ..... RoverMed Biosciences ..... Rowbot Systems .... Royole ..... RQx Pharmaceuticals .... RRE Solar .... Rubicon Tech ... Rubigo Therapeutics .... Rubitection ..... Rubius Therapeutics .... RubrYc Therapeutics ..... Rules-Based Medicine ... Rushford Hypersonic ... Ruud Lighting ..... RxFunction ... RXi Pharmaceuticals ... RxMedic .... Rypos

S2 ... Sadasis .... SafeShot .... Saffron Technology .... Sage Electrochromics ... SADAR 3D .... Sage Science ... Sage Therapeutics ...Sakti3 ... Salarius Pharmaceuticals ..... Salient Surgical Technologies ... Salix Pharmaceuticals ... Salutaris Medical Devices ..... SAM Medical .... Sancilio Pharmaceuticals .... Sand 9 . .. Sandia Biotech .... Sangamo Biosciences ... Sangart ... Santalis Pharmaceuticals ..... Santarus .... Sanuwave Health .... Sapheon .... Sapphire Energy .... SARbarcode .... Sarda Technologies ... Sarepta Therapeutics .... SatCon Technology ... Satori Pharmaceuticals .... Savara Pharmaceuticals .... Savi ... SBH Sciences ... Scanadu ..... Scholar Rock .... Sciaderm ..... SciClone Pharmaceuticals ... Sciencescape ..... Scientific Conservation .... Scientific Research ... Scientific Solutions ... Scientific Systems ... SciFluor Life Sciences ... Scilex Pharmaceuticals .... Scinovia ..... Scioderm .... SciQuest ... Scopic Software ... Scout Bio .... Scynexis ... SD Catalyst Group ... SDL .. SeaChange ... Seacoast Science ... Seahawk Biosystems ... Seahorse Bioscience ... Seaside Therapeutics .... Seattle BioMed ..... Seattle Genetics ... Seattle Medical Tech .... Sebacia .... Second Genome .... Second Sight Medical Products ... Securboration ..... Secure Computing ... Sedia Biosciences ..... Seeo ....Segetis ... Seldon Labs ... Selecta Biosciences ... SELLAS Life Sciences Group .... Sema4 Natalis ..... Semiconductor Laser ... SemiProbe ... Semler Scientific .... Semma Therapeutics .... Semnur Pharmaceuticals .... Semprius ... Semprus BioSciences .... Sencera International ... SenesTech ..... SenGenix .... Senior Scientific ..... Seno Medical Instruments .... Senomyx ... SensAble Technologies ... Sense .... Sense Diagnostics .... Senseonics ..... Sensintel .... Sensiotec ... Sensors Unlimited ... SensorTran ... Sentelligence ... Senti Biosciences ..... Sentient Technologies ..... SentreHEART ..... Sepracor ... SeprOx .... SeQual Technologies ... Sequella ... Sequel Pharmaceuticals .... Sequenom ... Sequenta ... Sequent Medical .... SeraCare Life Sciences ... Seragon Pharmaceuticals .... Seraxis ..... Seres Health .... Serenex ... Sermonix Pharmaceuticals .... Servergy ..... SetPoint Medical .... Seurat Therapeutics ..... Seventh Sense Biosystems ... SGB Biofuels ..... SGX Pharmaceuticals ... Shamrock Energy ... Shape Pharmaceuticals ..... Shape Security .... Shapeways .... Sharklet Technologies ..... Sharp Edge Labs ..... Shift Labs ..... Shiloh Labs ....Shine Medical Technologies ... Shore Thing Shellfish .... Shuttle Pharmaceuticals ..... Si-Bone .... Sicel Technologies ... SiCortex ... Sideris Pharmaceuticals ..... SI Diamond Technology .... Sienna Biopharmaceuticals ..... Sierra Energy ..... Sierra Monolithics ... Sierra Nevada ... Siga Technologies ... SiGe Semiconductor ... Sigilon Therapeutics .... Sigma Labs (NM) .... Sigma Technologies .... SignalFX (formerly Signal Fuse) ..... Signal Genetics .... Signature Genomic Laboratories ... Sila Nanotechnologies .... Silarus Therapeutics .... Silatronix .. Silent Power ... Silicon Biosystems Menarini ..... SiliconBlue .... Silicon Laboratories ... Silicon Mountain Design .. Silicon Space Technology .... Siluria ... Silverbrook ... Silverback ..... Silvergate Pharmaceuticals .... Silver Spring Networks ... Simbol Materials ... Simply Incredible Foods ... SiMPore ... Simulation Technology and Applied Research ... Simulution ... Singlera Genomics ..... Singulex ... Sinmat ... SiNode Systems ..... Sintact Medical Systems ..... Sion Power ... SiOnyx ... Sioux Manufacturing ... Sirga Advanced Biopharma .... Sirion Therapeutics ... Sirnaomics ..... Sirna Therapeutics ... Sirtris Pharmaceuticals ... Sisu Global Health ..... Sitari Pharma ..... Skybox Imaging .... Skyhawk Therapeutics ..... Skyline Medical .... Skyonic ... SLI .. SLIPS Technologies ..... SmartCells ... Smart Modular Technologies ... SmartSpark Energy Systems ... Smart Structures .... Smart Wires ..... Smisson-Cartledge Biomedical ... Smooth-Stone ... SNP Bio ..... Socrates Health Solutions .... Soft Machines .... Soft Robotics ..... SoftSwitching Technologies ... Soft Tissue Regeneration ... Soladigm (now View) ..... SolAero Technologies ..... Solaicx .... Solais Lighting .... Solana Surgical ..... SolaranRx ..... SolarBridge Technologies ... Solar Connection .... Solarea ..... Solaria ... Solarmer Energy ... Solar Power Technologies ... SolarWinds ... Solazyme ... Solexant ... Solexel ... SolFocus ... Soliant ... Solid Biosciences .... Solid Concepts ..... SolidEnergy .... Solidus Biosciences ..... SolidWorks ... Soliris .... Soliton ..... Solixia ... Solix Biofuels ... SolMap Pharmaceuticals ... SoloHealth ... Solomon Technologies ... Solo Power .... Solstice Biologics .... Soluble Therapeutics .... Solx .... Solyndra ... Soma .... SomaLogic .... Somatic Labs ..... Somaxon Pharmaceuticals ....Somna Therapeutics ... Sonalysts ... Soneter .... Sonex Aircraft ... Sonitus Medical ... Sonivate ..... SonoSite ... Sonovex .... Sontra Medical ... Sonus Pharmaceuticals ... Sophiris Bio .... Sophono ..... Soraa .... Sorrento Therapeutics .... Soteira ... Sostena .... Sotera Wireless ... Sound Pharmaceuticals ..... Sourcefire ... Source MDx ... Southwall Technologies ... Southwest Windpower ... Space Dev ... Spaltudaq ... Spansion .... Sparkbuy ..... Spark Therapeutics .... Sparo Labs ..... Spatial Photonics ... SPEC ..... Spectra254 .... Spectragenetics .... Spectral Energies ..... Spectral Systems ..... Spectranetics ... SpectraWatt ... Spectro Coating ... SpectrumS4 .... Speech Tails ... Speer Medical .... Spero Therapeutics ..... Spinal Modulation ..... Spinal Restoration ... Spinal Simplicity ..... SpineGuard ... Spineology ... Spine Wave .. Spintech .... Spin Transfer Technologies .... SpiralGenetics .... Spiration ... Spire ... Spirox (formerly Nasoform) ..... Spoonflower .... Spotfire ... Spot On Sciences ... Spredfast ... Spring Bank Pharmaceuticals ... SpringLeaf Therapeutics ... SpringWorks Therapeutics .... Spyrix ....SQZ Biotech ..... SRL ... Staktek Holdings ... Standard Bariatrics .... STAR Cryoelectronics ... Starfire ... Startech Environmental ... Startup Circle Pharma .... StarVision Technologies .... Stasys Medical ..... SteadyMed Therapeutics ..... Stealth Therapeutics ... Steel City Optronics .... Stellaray .... Stellar Biotech .... Stellar Science .... Stellent .... Stemagen ... StemBioSys .... Stem Cell Assurance (Now BioRestorative Therapies) .... StemCells ... Stemcentrx ..... StemCo Biomedical ... Stemgent ... StemImmune .... Stemina Biomarker Discovery ... Stemonix ..... Stem Pharm .... Stereotaxis ... Sterilmed ...... Sterling Semiconductor ..... StimMed ..... Stirling Energy .... Stoke Therapeutics ..... Stottler Henke ... Straight Flight .... Stratagene ... Strata Oncology ..... Stratasys ... Stratatech ... Strategic Response Initiatives .... Stratos Genomics ... Stromedix .... Strongbridge Biopharma ..... Sucampo Pharmaceuticals ..... Summit Technology .... Sun BioPharma ..... Sun Catalytix .... Sunesis Pharmaceuticals .... SunHealth Solutions ... Suniva .... Sunovion Pharmaceuticals ... SunPower ... Sun Power Biodiesel ... Sunrise Ridge Algae ....Sunshine Heart .... Suntech ... Suono ..... Superconductive Components ... Superconductor Technologies ... SuperDimension ... SuperFlex ..... SuperPower ... Superprotonic .... SupraSensor ..... Surefire Medical .... Surface Logix ... Surface Oncology ..... Surgient ... SurgiQuest .... Surmet ... SurModics ... Suros Surgical Systems ..... Surrozen .... Sustainable Oils .... SustainX ... Sutro Biopharma ..... Sutron ..... SutroVax ..... SuturePro Technologies (now Ceterix) .... SuviCA .... SuVolta ... Suzlon Rotor ... SVS ... SPEC ... Swallow Solutions .... SweetSpot Diabetes Care ... Swift Biosciences .... Syagen Technology ... Symbiomix Therapeutics ..... Symbiont Web ... Symbotic ... Symetrix .... Symic Biomedical ..... Symyx Technologies ... Synack .... Synageva BioPharma ... SynAm Vaccine .... SynapDx .... Synaptics ... SynCardia Systems ..,.. Synchroneuron .... SynchroPET .... Syndax Pharmaceuticals ... Syndexa Pharmaceuticals .... Synedgen .... Synergy Biomedical .... Synergy Pharma ..... SynGen .... Synlogic ..... Synopsys .... SynSonix .... Synta Pharmaceuticals ... Syntax-Brillian ... SyntheMed ... Synthetic Biologics ..... Synthetic Genomics .... SyntheZyme ..... Synthorx .... Syntimmune ..... Syntrix Biosystems .... Syntronics .... Synvitrobio ..... Syros Pharmaceuticals .... Sysgain .... Syslogic .... Systagenix Wound Management ..... Systems and Processes Engineering SPEC ... Systima Technologies ..... Sytera

T2 Biosystems ... T3D Therapeutics ..... Tabula ... Taconic BioSciences ..... Tactile Systems Technology .... Tactiva Therapeutics ..... TAI Diagnostics ..... Talecris Biotherapeutics ... Taligen Therapeutics ... Talima Therapeutics ... Tal Medical ... Talon Therapeutics ... Tandem Diabetes Care ... Tangen Biosciences ..... Tango Therapeutics ..... Tanox ..Tantaline .... TapImmune .... Tarari ... .Targacept ... TargeGen ... Targ-Anox ... Targanta ... Targazyme (formerly)America Stem Cell.... Targeson ... Targeted Genetics ... Targeted Growth ... Taris Biomedical .... Tarveda Therapeutics ..... Tascent .... Tauriga Sciences .... Taxa Biotechnologies ..... Taxon Biosciences .... Taxus Cardium (formerly Cardium Therapeutics) ... Taylor Devices ..... TCR² Therapeutics ..... TDA Research .... Tealium ..... TearScience ... Tech-X .... Techniscan Medical Systems ... Technology and Devices Int'l ... TechTol Imaging ... TELA Bio ..... Telecardia ... TeleContinuity ... Telefactor ..... Telemedicine Up Close operates as DxUpClose ...... Telik ... Tempest Therapeutics ..... Templex Technology... Tempus ..... Tenax Therapeutics .... Tenaya Therapeutics ..... Tendril ... Tendyne Holdings ..... Tensha Therapeutics ... Tepha ... TeraDiode .... TeraDiscoveries (now Cloud Pharma) .... Terapio ... TeraStor ... Terrabon ... Terrajoule ... TerraMetrics ... Terumo BCT .... Terus Technologies .... TESARO .... TeselaGen Biotechnology .... Tessera Technologies ... Tethys BioScience .... Tetra Discovery Partners .... Tetragenetics ... TetraLogic Pharmaceuticals ... Tetraphase Pharmaceuticals ... TetraVue ... Tezzaron Semiconductor .... TFF Pharmaceuticals .... TGS Knee Innovations ... TG Therapeutics .... Thar Pharma .... Thalchemy ..... The ExOne .... The Medicines ..... Therabron Therapeutics ..... Theraclone Sciences ... Theragenics .... Therametric Technologies ... Theranos .... Therion Biologics ... Thermacore ... Thermage ... Thermal Gradiant .... Thermal Spray Technologies .... ThermalTherapeutic Systems ... Thermedical ... ThermoAura .... ThermoCeramiX .... ThermoGenesis .... Thermon ... TherOx .... Thesan Pharmaceuticals .... Theseus... Thetis Pharmaceuticals ... ThingMagic... Third Wave Technologies .. Thoratech Tech ... Thorley Industries .... ThreeRivers 3D ..... Threshold Pharmaceuticals ... ThromboVision .... Thyritope Biosciences .... Tiax ... Tibbetts Industries ... Tibion ..... Tilera ... Tillges Technologies ... Tioma Therapeutics ..... TissueGene ..... TissueLink ... Tissue Regeneration Systems .... Titan Pharmaceuticals .... Titan Spine ..... TJ Technologies .... TLC Precision Wafer ... Tmunity Therapeutics .... Tobira Therapeutics .... Tocagen ... Tokai Pharmaceuticals .... Tolerx .... TomoTherapy ... Tone Tree ..... Topia Technology .... TopicalRemedy .... Topokine Therapeutics .... Torax Medical ... Torque Therapeutics ..... Total Immersion ... TotipotentRx .... Totus Solutions .... Trace Genomics ..... Tracon Pharmaceuticals ... TranS1 .... Transatomic Power .... Transcend Medical ...Transcept Pharmaceuticals .... TransCorp ..... Transcriptic ..... TransEnterix ... Transgenomic ... Translattice ..... TransMedics ... Transmeta ... TransMolecular ... Transphorm ..... TransTech .... TransTech Pharma (now vTv Therapeutics) ... Transzyme Transzyme Pharma ... Traverse Biosciences ... Traycer Diagnostic Systems ..... Trellis Bioscience ... Trellis Earth Products ... Trevena ... Trevi Therapeutics ..... Trex Enterprises ... Triad Semiconductor .... Tri Alpha Energy ..... Triangle BioSystems .... Tribogenics .... Tribologix .... Trice Orthopedics .... Tricida ..... Trident Systems ... Trilumina .... Trimble Navigation .... Trimeris ... Triquint Semiconductor ... Triton Systems ... Trius Therapeutics ... TriVascular Technologies .... Trovagene ..... Trubion Pharmaceuticals ... Tru-D SmartUVC ..... True Diagnostics .... True Health Diagnostics .... True North Therapeutics ..... TruTouch Technologies ..... Try Eco ..... Tryton Medical ... Tularik .... Turtle Mountain Communications .... TVA Medical ... Twelve .... Twin Star Medical ... Twist Bioscience ..... TwoXAR ..... Tyrosine Pharmaceuticals .... Tyrx

uBiome .... UCAN ... UES ... Ulthera .... UltraCell ... Ultragenyx .... Ultralife Batteries ... Ultramet... Ultradian Diagnostics ..... Ultraviolet Sciences ... Unbounded Robotics .... Unchained Labs .... UNIAX ... Unica ... Unidym ... UniEnergy Technologies ..... Unified Nexsys .... Unilife ..... Uni-Pixel .... Uniqure .... United Devices ... United Therapeutics ... United Therapies ..... Unity Biotechnology .... Universal Cells ...... Universal Display ... Universal Robots ..... Universal Technical Resources .... Universal Technology .... Unleash Immuno Oncolytics ..... Unum Therapeutics .... Unwired Nation ... Uptake Medical ... UQM Technologies ... Urbix Resources .... Urigen Pharmaceuticals .... UroGene Pharma ..... US Nanocorp ... Uroplasty ..... US Bioscience ..... US Silicones ... UTC Power .... Utilidata ... Utron ..... UVision360

Vaccinex ..... Vaccinogen .... Vader Systems ..... Vala Sciences ....Valencell ... Valence Technology .... Validity Sensors ... Valmont Industries .... Vanda Pharmaceuticals ... Vanguard Space Technologies ..... Vapogenix ..... Vascular Biogenics (also VBL Therapeutics) ..... Vascular Designs ... Vascular Genesis ..... Vascular Pathways ... Vascular Pharmaceuticals .... Vascular Solutions ..... Vasculox .... VasoGenix Pharmaceuticals ... Vasoptic Medical ..... Vativ Technologies ... Vaxart ... Vaxess Technologies .... VaxGen ... VaxInnate ... vCalc .... Vecna Tech ... Vectorlogics .... Vedanta Biosciences .... Veeva Systems .... Veezyon ... VeinAid ... Velano Vascular .... Velicept Therapeutic ..... Velocimed ... Velomedix ... VenatoRx Pharmaceuticals ..... Venaxis ..... Vendormate .... Veniti ... Vensun Pharmaceuticals .... VentiRx ... Ventria Bioscience ... Ventrix ..... Ventrus Biosciences ... Veracode ... Veracyte ... Veran Medical Technologies ..... Verastem ... VeraSun Energy ... VerAvanti .... Verax Biomedical ... Verdezyne ... Vergent Bioscience ..... VerinataHealth ... Verenium ... Vericel (formerly Aastrom Bio) .... Verifica-BG ... Veritas Genetics ..... Vermillion .... Vermont Composites ...Veros Systems ... Verrica Pharmaceuticals .... Versar .... Versartis ... Vestagen Technical Textiles .... Vestaron .... VerteraSpine ..... Vertex Pharmaceuticals ... VeruTEK Technologies ... Vesper Medical ..... Vextec ... VGBioCogCubed .... V-Glass .... VGo Communications ... VGX Pharmaceuticals ..... ViaCell ... ViaCyte .... Viacor .... Viamet Pharmaceuticals ... ViaSat ... Via Separations .... Vical . .. Vicarious .... Vicus Technologies .... Vidacare ... View ..... Viking Therapeutics .... Vion Pharmaceuticals ... ViraCor Laboratories ... Viracta Therapeutics ..... Viral Genetics .... Virdante Pharmaceuticals ... Virdia .... Virent Energy Systems ... Viresco Energy ... Virobay .... ViroPharma . .. ViroXis ... Virtify . VirtualScopics .... Virtusa ... Viscardia ..... VisEn Medical ... VisiGen Biotechnologies ... VisionGate ..... VisionQuest ..... Vision-Sciences ... Vistagen Therapeutics ... Vistec Lithography ... Visterra ... Visualase .... Vitae Pharmaceuticals ..... VitalMedix ... Vital Therapies ...... Vital Vio .... VitaPath Genetics ... Vitriflex .... Vium ..... Vivex Biomedical .... Vividion Therapeutics ..... Vivisimo .... Vixar ... Vixel ... Vixiar Medical ..... Vizzario .... Vlingo ... VLST ..... VMware ... Voci Technologies .... Volcano .... VoltServer ... VORAGO Technologies (previously Silicon Space Technology) ..... Vorbeck Materials ... Vor BioPharma ..... Vortex Biosciences ..... Vortex Medical ... Voxel .. voxeljet ..... Voyager Therapeutics .... Vtesse .... VT Silicon .... vTv Therapeutics (formerly TransTech Pharma) ..... VUV Analytics .... Vuzix .... Vyriad .... Vyrx Pharmaceuticals ..... VytronUS

WaferGen Biosystems ... Wakonda Technologies ... Walker Magnetics Group ... Waste2Watergy .... Waveband ..... Wave Computing ..... Waveguide ..... WaveRx ... Weinberg Medical Physics .... WellStat Therapeutics .... Whole Biome ..... Whole Trees ..... WiBotic .... Wicab ..... WildcatDiscovery .... Wiliot ..... Willow Garage ... Wilocity .... Wilson Greatbatch .. Wilson Tool International .... Wilson Wolf Manufacturing ... WiMax.com ... Windlift ... Windtree Therapeutics ..... WinSanTor .... Wintegra ... WISErg .... Wizbe Innovations ... WMR Biomedical (now Arsenal Medical) ... Wolf Technical Services ... WoundZoom .... Woven Orthopedic Technologies .... Wright Materials Research ... Wright Therapy Products ..... W Solar Group

X4 Pharmaceuticals ..... Xanofi ... Xanthus Pharmaceuticals ... XBiotech USA ..... X-Body Biosciences ... Xcede Technologies ..... XCELL BIOLOGIX ..... Xcell Biosciences .... Xcellerex ... XChanger Companies .... Xencor .... X-energy ..... Xenetic Biosciences .... Xenex Disinfection Services .... Xenex Healthcare Services ... XenoGen Biosystems .... Xenomics ... Xenoport ... Xeris Pharmaceuticals ... Xetrios Therapeutics .... XF Technologies .... xG Technology .... Xidex ... Xitronix ... XL Hybrids ... Xlumena .... Xoc Pharmaceuticals ..... Xollai ... Xolve (formerly Graphene Solutions) ... Xoma ... XProSciences (now Icagen) ..... X-Ray Optical .... X-Spine .... XSunX ... Xtalic .. Xtant Medical Holdings ..... Xtent ...Xtreme Power ... XTuit Pharmaceuticals .... Xunlight .... Xynomic Pharma

Yan Engines ... Yardney Technical Products .... Y-Carbon ... Yulex .... Yumanity Therapeutics .... Yurie

Z ... Zacharon Pharmaceuticals .... ZafGen .... Zavante Therapeutics ..... ZBB Energy ... ZeaChem ... ZeaKal .... Zebra Imaging .... Zebra Medical Vision (Israel) ..... Ze-gen ... ZenBio ... Zenomics .... Zenverge ..... Zeo .... Zephyr Technology ... ZeptoMetrix .... ZeroFOX .... Zero Locus .... ZetaRx Biosciences .... Zilker Labs ... Zinc Matrix Power ... Zintera ..... Ziopharm Oncology ... Ziptronix .... Zogenix ... Zosano Pharma ... ZPower ... ZS Genetics ..... zSpace ..... ZS Pharma ... ZSX Medical .... Zumobi ... Zunum Aero ..... Zurex Pharma ... Zwitter Technology .... Zyga Technology .... Zygo ... Zymergen ..... ZymoGenetics ... Zynerba Pharmaceuticals .....Zymeworks ..... Zyomyx ... Zystor Therapeutics ... Zyvex Technologies

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