Precision Biosciences (RESEARCH TRIANGLE PARK, NC; $500K SBIR) up 25% [Nov 14, 19]
XBiotech up 15% [Nov 14, 19]
VistaGen Therapeutics (South San Francico, CA; $9M SBIR) announced topline results from the ELEVATE study, a Phase 2 study of AV-101, its NMDA (N-methyl-D-aspartate) receptor glycine site antagonist, as an adjunctive treatment of major depressive disorder (MDD). In this study, the AV-101 treatment arm did not differentiate from placebo on the primary endpoint (change in the Montgomery-Åsberg Depression Rating Scale (MADRS-10) total score compared to baseline) [company press release, Nov 14, 19]
Exicure (Cambridge, MA; $1.5M SBIR)a pioneer in gene regulatory and immunotherapeutic drugs utilizing spherical nucleic acid (SNA™) technology, today announced that Allergan’s wholly-owned subsidiary, Allergan Pharmaceuticals International Limited, and Exicure, Inc. have entered into a global collaboration agreement to discover and develop novel treatments for hair loss disorders based on Exicure’s proprietary SNA technology. [company press release, Nov 14, 19]
IDEAYA Biosciences (South San Francisco, CA; no SBIR) up 47% [Nov 13, 19] announced financial results and that financial results and significant progress on our Phase 1/2 tissue-agnostic basket trial evaluating IDE196 in patients with solid tumors harboring GNAQ or GNA11 (GNAQ/11) mutations, including metastatic uveal melanoma (MUM), cutaneous melanoma and colorectal cancer. [company press release, Nov 13, 19]
Applied DNASciences (Stony Brook, NY; $1M SBIR) down 72% [Nov 13, 19] Announced Pricing of Upsized $12.0 Million Underwritten Public Offering [company press release [Nov 13, 19]
Molecular Templates (Austin TX; one SBIR in 2010) down 18% [Nov 13, 19] reported financial results
Reata Pharmaceuticals (Plano, TX; at least one SBIR) announced that its investigational drug for those with Alport syndrome, bardoxolone methyl (bard), met the main goal of a Phase 3 clinical trial. After 48 weeks of treatment, patients in the study who received bard saw their kidney function—as measured by a blood test that estimates how much blood passes through filters in the kidneys each minute—improve compared to a placebo ... company now plans to ask the FDA to review the drug. No FDA-approved treatment for Alport syndrome currently exists. [Sarah de Crescenzo, xconomy.com, Nov 12, 19]
China’s venture-capital boom, which spawned some of the world’s most valuable technology companies and dozens of rags-to-riches entrepreneur tales in recent years, has come to an end. [Jing Yang, Wall Street Journal, Nov 14, 19]
Applied DNA Sciences (Stony Brook, NY; $1M SBIR) up 332% [Nov 12, 19] a leader in large-scale Polymerase Chain Reaction (PCR)-based DNA manufacturing, announced the successful DNA tagging of leather at one of the world's largest tanneries based in Asia. The work follows a successful research project undertaken within the UK that demonstrated SigNature(R) DNA could be successfully used to trace the hide of an animal from a farm to the product in a store. [company press release, Nov 11, 19]
Solid Biosciences down 74% [Nov 12, 19] reported that [FDA] has notified the company that IGNITE DMD, its Phase I/II study of SGT-001, has been placed on clinical hold. [company press release, Nov 12, 19]
HDL Therapeutics (Vero Beach, FL, no SBIR, founded 2009) devicemaker announced data from a registrational study of its PDS-2 device. .... the data showed that the treatment, which involves enriching a patient’s plasma with a certain kind of “good” cholesterol, reduced the buildup of plaque by 18% in coronary arteries after seven weeks. [Amirah Al Idrus, Fierce Biotech, Nov 11, 2019] total funding $4.5M [crunchbase.com]
Corindus Vascular Robotics (Waltham, MA; no SBIR) just days after Siemens Healthineers closed its $1.1 billion acquisition of the company, reported that it has completed its first machine-assisted brain surgery procedure in humans. [Conor Hale, Fierce Biotech, Nov 8, 2019]
What matters? Polarized politics mean that voters’ views of the economy are increasingly shaped by their party preference, rather than the other way around. And for some key voting blocs, noneconomic issues such as immigration, race relations and Mr. Trump himself have superseded economic concerns in determining their vote. [Greg Ip,WSJ, Nov 12, 19] A serial fantasizer has an emotional grip on a huge section of the electorate.
89bio (San Francisco, CA and Israel; no SBIR) up 30% [Nov 11, 19] after IPO to raise $89M
NextCure down 53% [Nov 11, 19]
RAPT Therapeutics down 30% [Nov 11, 19]
Exact Sciences completes $2.8B acquisition of Genomic Health [Milwaukee Business Journal, Nov 8, 19]
Destroying a system. Secretary of State Mike Pompeo has been credited with improving State Department staffing and morale, but his treatment of U.S. Foreign Service officers caught in the impeachment inquiry has undercut those efforts, according to current and former career professionals upset over his recent actions. [Jessica Donati, Wall Street Journal, Nov 11, 19] a 17th century scheme to re-elect the monarch at any cost
Hear no evil. E.P.A. to Limit Science Used to Write Public Health Rules [Lisa Friedman, NYTmes, Nov 11, 19] The overriding goal: corporate profits.
RAPT Therapeutics up 26% [Nov 8, 19]
Dermira up 18% [Nov 8, 19]
Anaptys Bio (San Diego, CA; no SBIR) down 72% [Nov 8, 19] announced topline data from its ATLAS trial, a Phase 2b randomized, double-blinded, placebo-controlled, multi-dose study in approximately 300 adult patients treated with etokimab in moderate-to-severe atopic dermatitis. Each of the etokimab dosing arms failed to meet the primary endpoint of the trial. [company press release, Nov 8, 19],
Biotech startup eGenesis (spun out of Harvard in 2014), which is applying gene editing to animal organs in order to make them suitable for human transplant, has raised $100 million to ramp up work on its kidney program and bring it into human testing. [xconomy.com, Nov 8, 19]
A drug that Celgene and Acceleron Pharma developed to treat low red blood cell levels in patients who have a rare blood disorder now has regulatory clearance to enter the market. The FDA on Friday approved luspatercept (Rebloyzl) for patients who have beta thalassemia, an inherited disorder that leads to anemia, or low levels of oxygen-carrying red blood cells. [Frank Vinluan, xconomy.com, Nov 8, 19]
It's a buyer's market for unicorns. Public investors are getting increasingly picky about the financial fundamentals of venture-backed companies planning or carrying out IPOs. That's upending the prior status quo - in which unicorns and their underwriters largely dictated valuations - and impacting the favored startup strategy of scaling fast and breaking things. [Joanna Glasner, Crunchbase, Nov 8, 19]
Big tech threat. A raft of research shows us that trust in liberal democracy, government, media and nongovernmental organisations declines as social media usage rises. ..In the US, of course, personal data is being collected, monetised and weaponised in ways that we are only just beginning to understand, and monopolies are squashing job creation and innovation. At this point, it is harder and harder to argue that the benefits of platform technology vastly outweigh the costs. [Rana Foroohar, The Guardian, Nov 8, 19]
The American people are ill informed, and this quadrennial circus called a presidential election makes matters worse, as it becomes a contest in which candidates compete to proclaim their fealty to American exceptionalism while insisting that no alternative to American global leadership can conceivably exist. They all promise if elected to ensure that ours remains not only the best but the strongest military in the world, now and forever, as if a dearth of military power has somehow hampered U.S. policy. [Andrew Bacevich, Boston Review, April 2016]
RAPT Therapeutics (South San Francisco, CA; no SBIR) up 48% [Nov 7, 19], a clinical-stage immunology-based biopharmaceutical focused on discovering, developing and commercializing oral small molecule therapies for patients with significant unmet needs in oncology and inflammatory diseases, announced the pricing of its [IPO] to raise $36M. [company press release, Nov 7, 19]
DexCom (one SBIR, market cap $14B) up 27% [Nov 7, 19]
Quanterix (Lexington, MA; one SBIR) up 23% [Nov 7, 19] reported quarterly results
Synaptics up 16% [Nov 7, 19]
Arcadia Biosciences down 27% [Nov 7, 19] reported quarterly results
Aerie Pharmaceuticals down 27% [Nov 7, 19] reported quarterly results
Arkuda Therapeutics (Cambridge, MA) leveraging new insights into progranulin and lysosomal biology to develop medicines to change the trajectory of neurodegenerative disease, announced the completion of a $44 million Series A financing. [company press release, Nov 7, 19]
Imbed Biosciences (Fitchburg, WI; $3M SBIR), announced it has closed its Series A Preferred Stock equity financing, which was expanded to $4 million due to investor demand. [company press release, Nov 7, 19]
NASA has a nice piece by Mike DiCicco of Goddard Space Flight Center on commercialization from four NASA SBIR/STTR awardees. Read the stories.. Companies: Serionix (Champaign, IL), Cambrian Innovation (Watertown, MA), Electric Power Systems (Lombard, IL), Zeus (Orangeburg, SC)
Exploiting Insecurity. Right now, we are asking millions of Americans to accept high immigration while they are already living with maximum insecurity. Their wages are declining, their families and communities are fragmenting, their churches are shrinking, government services are being cut, their values and national identity feel unstable. Of course they are going to react with suspicion if suddenly on top of all this they begin to feel like strangers in their own place. [David Brooks, NYTimes, Nov 7, 19] why a scheming insulting amoral liar can get elected President.
The Department of Energy will award $128M to support 75 research projects that seek to advance the development of solar technologies. Most money went to academic and large businessses. Several awards went to former SBIR winners: Energy Materials (Norcross GA one SBIR) won a $4M Solar project award to create new methods to deposit layers of material to make the cell, develop a high-speed process ; Leading Edge Crystal Technologies (Gloucester, MA; one SBIR) won $2.5M to develop a floating-silicon method for producing high-quality single crystalline wafers ; Sunvapor (Livermore, CA ; one SBIR) won $2.5M to show how using enormous tanks that normally store liquefied petroleum gas can be used to accumulate and store solar-generated steam ; Brayton Energy (Hampton,NH; $3M SBIR) won $700K to partner w Oak Ridge Lab to examine examine creep behavior—the tendency to deform under mechanical stress—in thin-sheet nickel alloys; Ceramic Tubular Products (Lynchburg, VA; $3.2M SBIR) won $1.9M to develop silicon carbide composite receiver tubes for molten chloride salt and liquid sodium receivers; Echogen Power Systems, (Akron, OH; $300K SBIR) won $4.4M to develop a large-scale, low-cost, single-shaft compressor for supercritical carbon dioxide (sCO2) power cycles; Osazda Energy (Albuquerque, NM; one SBIR) won $1M to develop a cost-effective metal paste that strengthens the metal connections in solar cells; Scion Plasma (East Lansing, MI; $200K SBIR) won $1M to develop a tool that rapidly deposits transparent conductive oxide onto heterojunction silicon with intrinsic thin layer (HIT) solar cells; Swift Coat (Peoria, AZ; one SBIR) won $1M to make and scale multilayer, anti-reflective and anti-soiling coatings for solar glass [Jane Edwards, govconwire, Nov 7, 19]
NextCure (Beltsville, MD; no SBIR, founded 2015) up 243% [Nov 5, 19] a clinical-stage biopharmaceutical company committed to discovering and developing next-generation immunomedicines for cancer and other immune-related diseases, announced that the company will host and webcast an event with its Chief Medical Officer [to]discuss updated clinical results from the Phase 1 portion of its ongoing trial with NC318 that are being presented earlier in the day at SITC. [company press release, Nov 5, 19]
Paratek Pharma up 25% [Nov 5, 19]
Immunigen up 23% [Nov 5, 19]
Arcadia Biosciences up 19% [Nov 5, 19] announced it has secured its first purchase commitment for its high-fiber bread wheat for 2020 [company press release, Nov 5, 19]
Epizyme up 18% [Nov 5, 19]
Myriad Genetics down 40% [Nov 5, 19] announced large quarterly loss
A single, self-funded competitor ran away with top honors in the latest round of the DARPA Subterranean (SubT) Challenge, which promotes the development of next-gen war robots that can navigate and map underground tunnels and caves. Besting teams from top institutions with an event score of 50 total points, Coordinated Robotics, represented by a single engineer named Kevin Knoedler, won the Virtual Tunnel Circuit event. Knoedler will earn $250,000 for his first-place finish. [Greg Nichols for Robotics, zdnet.com, Nov 5, 19]
Nervous in the service. Last month, [nearly 100-year-old American Foreign Service Association] began a fundraising campaign—soliciting donations from members and the public alike—for a legal defense fund for any FSOs asked to testify before Congress. ... caught in the middle of the impeachment battle. Congress has subpoenaed several AFSA members, who are being told by State not to cooperate. [Eric Katz, govexec.com, Nov 5, 19] Foreign Service has the most demanding entry competition of all government employment. Federal employees in several agencies have reason to fear the President's self-serving political machinations and appointment of unconfrmed lobbyists and their ilk to agency leadership in rejection of the rule of law.
microbiome company Arranta Bio (Watertown, MA: no SBIR, founded 2019) announced the completion of an $82 million funding round and a strategic partnership with Thermo Fisher Scientific. (company press release, Oct 30, 19]
Cancer drug maker Karyopharm Therapeutics reported revenues of $12.8 million for its third quarter, driven by the commercial launch of its recently approved cancer drug, Xpovio, exceeding analyst expectations. [Yahoo Finance, Nov 4, 19]
biotech startup Cocoon Biotech (Cambridge, MA; no SBIR, founded 2013) recently filed an amendment to an SEC Form D to reveal that it sold more than $4 million in a debt offering. [Sean Whooley, massdevice.com, Nov 4, 19] total funding $4.3M [crunchbase.com]
Intrepida Bio (San Diego, CA; no SBIR), a company formed around a preclinical antibody developed by Italian pharmaceutical company Biouniversa. ... backed by $9.5 million ... launched last week, plans to advance work by Biouniversa’s Maria Caterina Turco, who studied a protein, BAG3, that is overexpressed by some cancer tumors—especially pancreatic tumors. [Sarah de Crescenzo, xconomy.com, Nov 4, 19]
Hoth Thera up 42% [Nov 1, 19]
Immunogen up 28% [Nov 1, 19]
Eloxx Pharma up 15% [Nov 1, 19]
Dynetics (Arlington, VA and Huntsville, AL; at least 30 SBIRs) has secured a potential 10-year, $737.9M contract for support services to a facility where the Defense Intelligence Agency assesses data on foreign weapons systems. DoD noted the contract includes a five-year option period that could extend the performance of work through Oct. 31, 2029 [Matthew Nelson, govconwire.com, Nov 4, 19]
Eloxx Pharma (Waltham,MA; no SBIR, founded 2013) up 80% [Oct 31, 19] a clinical-stage biopharmaceutical company dedicated to the discovery and development of novel therapeutics to treat cystic fibrosis, cystinosis and other diseases caused by nonsense mutations limiting production of functional proteins, announced positive data demonstrating that ELX-02 results in a pronounced increase in both CFTR protein expression and mRNA stability further supporting its proposed mechanism of action, and that it was well tolerated with no serious adverse events in the Phase 1 program. [company press release, Oct 31, 19] The data ..., was so persuasive that [FDA] last week approved the three-drug combination, called Trikafta — five months ahead of the agency’s deadline. [Carolyn Y. Johnson, Washington Post, Oct 31, 19] total funding $38M [crunchbase.com]
An FDA advisory committee voted 9-7 to recommend that the agency pull an AMAG Pharmaceuticals drug for preterm birth from the market. The injectable treatment, hydroxyprogesterone caproate (Makena), failed to beat a placebo in a post-marketing study. [Frank Vinluan, xconomy.com, Nov 1, 19]
Tmunity Therapeutics (Philadelphia, PA; no SBIR), in pursuit of its vision to save and improve lives by delivering the full potential of next-generation T-cell immunotherapy, closed a $75 million Series B financing. [conpany press release, Oct 31, 19]
Dicerna Pharmaceuticals (Cambridge, MA; $3M SBIR) announced a research collaboration and licensing agreement with Roche (SIX: RO, ROG; OTCQX: RHHBY) to develop novel therapies for the treatment of chronic hepatitis B virus (HBV) infection using Dicerna’s proprietary GalXC™ RNAi platform technology. will receive $200 million in an initial upfront payment and may be eligible to receive up to an additional $1.47 billion over time for the achievement of specified development, regulatory and commercial milestones. [company press release, Oct 31,19]
Pandion Therapeutics (Cambridge, MA; no SBIR) and Astellas Pharma (Japan) announced a License and Collaboration Agreement directed toward the research, development, and commercialization of locally acting immunomodulators for autoimmune diseases of the pancreas. Pandion could receive up to $45 million as upfront and payments related to research and preclinical activities. Additionally, if Astellas develops and commercializes multiple candidates for multiple pancreatic autoimmune diseases, Pandion is potentially eligible to receive more than $750 million in future development and commercial milestone payments from Astellas. Pandion may also receive royalties on worldwide net sales of any commercial products developed through the collaboration. [joint companies press release, Oct 31, 9]
Oyster Point Pharma (Princeton, NJ; no SBIR), a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization of first-in-class pharmaceutical therapies to treat ocular surface diseases, announced the pricing of its [IPO] to raise $80M [company press release, Oct 30, 19]
Cyclerion Therapeutics (Cambridge, MA; no SBIR) down 80% [Oct 30, 19], a clinical-stage biopharmaceutical company developing soluble guanylate cyclase (sGC) stimulators for the treatment of serious and orphan diseases, announced topline results from its Phase 2 proof-of-concept study of praliciguat ... The study did not meet statistical significance on its primary endpoint of reduction in albuminuria from baseline as compared to placebo, but there was a trend toward improvement across the total intention-to-treat (ITT) study population. [compamy press release, Oct 29, 19] will lay off 30 of its 135 employees [Fierce Biotech, Oct 30, 19]
AMAG Pharma down 22% [Oct30, 19]
Disc Medicine (Cambridge, MA; no SBIR), a new biotech that aims to treat anemia caused by a variety of blood disorders, launched out of Cambridge, MA venture firm Atlas Venture on Tuesday with $50 million. The company is developing drugs to impact hepcidin, a liver hormone that helps the body regulate iron absorption. [Sarah de Crescenzo, xconomy.com, Oct 29, 19]
Fantasy exposed. The drop in business investment once again raises questions about the 2017 tax cuts. Washington Post columnist Catherine Rampell pointed out that business investment was a key selling point for the GOP tax cuts: “Mechanism by which the GOP tax cut was supposed to supercharge growth was by supercharging business investment,” she wrote Wednesday. “Business investment instead *fell* last quarter, by 3% annualized.” [Yuval Rosenberg and Michael Rainey, Fiscal Times, Oct 30, 19] Suckas! The people got a debt charge and the wealthy and business got a huge handout, which they simply banked. The richer you are, the lower your propensity to consume, we learned in Econ101.
Pfizer has dumped a bispecific antibody developed through its collaboration with MacroGenics (Rockville, MD; $2.5M SBIR). The solid tumor drug was the first partner-developed program based on MacroGenics' bispecific platform to enter the clinic, but it has fallen before clearing phase 1. In 2010, MacroGenics granted Pfizer the rights to candidates based on its bispecific antibody platform against two cancer targets. [Nick Paul Taylor, Fierce Biotech, Oct 29, 19]
Gilead Sciences has tapped FierceMedTech Fierce 15 winner Glympse Bio (Cambridge, MA; $800K SBIR) to help develop a non-invasive diagnostic test for nonalcoholic steatohepatitis, also known as the fatty liver disease NASH. [Conor Hale, Fierce Biotech, Oct 29, 19]
While pivoting to gene therapies, microcap Iveric bio (once Ophthotech, New York, no SBIR) posted positive data from its key eye drug Zimura (avacincaptad pegol). [Ben Adams, Fierce Biotech, Oct 28, 19]
mPower Technology (Albuquerque, NM; one SBIR) innovative solar cell technology startup, raised $2.5m in Series A funding [to] commercialize mPower’s solar cell technology, DragonSCALEsTM, in the aerospace market. [finsmes.com, Oct 28, 19]
ShiraTronics (Minneapolis, MN; no SBIR, founded 2019, the first spin off from NuXcel, a medical device accelerator) raised $33 million in Series A financing [to] to accelerate the development of a novel therapy that may significantly impact the lives of millions of patients who suffer from migraine headaches. [company press release, Oct 24, 19]
Nuvation Bio (New York and San Francisco, CA; no SBIR) a stealth biotechnology company developing proprietary therapies focused on oncology, announces the closing of $275 million in an oversubscribed Series A financing. [company press release, Oct 28, 19]
We're keeping the oil… Remember that, I've always said that. Keep the oil. We want to keep the oil — $45 million a month — keep the oil. We've secured the oil." [Donald Trump. Oct 28, 19] To the victor goes the spoils? Regrdless of international law on ownnership of land and mineral rights?
Melinta Thera down 23% [Oct 25, 19]
Rapt Therapeutics (South San Francisco, CA; no SBIR) filed to raise up to $75 million IPO after postponing an earlier attempt [Fierce Biotech, Oct25, 19]
Imagine that: the economists were right. Deficits have nearly doubled under President Trump, despite solid economic growth and low unemployment — and despite Trump’s vow to eliminate the federal debt in eight years. The Republican tax cut legislation of 2017 reduced revenues relative to projections, and bipartisan spending deals have raised spending. The Treasury estimates that the deficit will exceed $1 trillion next year, and budget experts expect it to remain above that level for years to come. [Yuval Rosenberg and Michael Rainey,Fiscal Times, Oct 25, 19] And the Liar-In-Chief and his yes-men were wrong. Another $300B added uselessly to the national debt.
Scientists Were Hunting for the Next Ebola. Now the U.S. Has Cut Off Their Funding. [Donald G. McNeil Jr., New York Times, Oct 25, 19] America Alone awaiting new viral disease invasions, like ebola, that a "national emergency" Mexican Wall won't stop.
Op Gen down 55% [Oct 24, 19]
U.S. government investment continues to decline, while other nations are increasing federal investment and strengthening foundational research. In fact, the White House’s proposed budget for 2020 decreases foundational research funding by 10% and applied research by 14% from the last fiscal year.22 By contrast, China doubled its foundational research funding in the last five years and spent a record $254 billion on R&D in 2017, narrowing the gap between it and the United States in R&D spending. [AN INNOVATION CHALLENGE FOR THE UNITED STATES, Aspen Institute, 2019] While America Alone shrimks its government and rejetcs immigrants.
Trump this week issued an executive order reinstituting the President’s Council of Advisors on Science and Technology (PCAST) to advise the president on matters involving science, technology, education, and innovation policy and named the first seven people to the council. The council will also provide the president with “scientific and technical information that is needed to inform public policy relating to the American economy, the American worker, national and homeland security, and other topics.” [SSTI, Oct 23, 19] But will he ask for or listen to any advice?
Op Gen down 38% [Oct 23, 19] announced the pricing of an underwritten offering [to] raise $9.4M [company press release, Oct 23, 19]
Macrogenics (Rockville, MD; $2.5M SBIR) down 38% [Oct 23, 19] announced topline results from the second pre-specified interim overall survival (OS) analysis for the Phase 3 SOPHIA study of margetuximab in patients with HER2-positive metastatic breast cancer who have previously been treated with anti-HER2-targeted therapies. [company press release, Oct 22, 19]
Athenex up 20% [Oct 22, 19]
Quantum computing firm IonQ (College Park, MD; no SBIR, founded 2016) announced the close of a $55M funding round .... brings its total raised to $77M. The move follows a major milestone for IonQ’s “trapped-ion” technology, which it says offers the most promise for reliable, scalable quantum computing. Recently, the startup built what it claims is the largest programmable quantum computer to date, demonstrating performance benchmarks that no others have yet matched. [DCInno, Oct 21, 19]
Miromatrix Medical (Eden Prairie, MN; $600K prior SBIR, founded 2008) was awarded a $1,97M [NIH] Direct to Phase II SBIR to advance the development of a bioengineered transplantable liver to address the chronic shortage of transplantable livers. [company presss release, Oct 21, 19] prior funding $57M. [crunchbase.com]
Takeda Pharmaceutical (Japan) and COUR Pharmaceutical Development (Skokie, IL; no SBIR) announced that Takeda has acquired an exclusive global license to develop and commercialize the investigational medicine CNP-101/TAK-101, an immune modifying nanoparticle containing gliadin proteins. Based on COUR’s antigen specific immune tolerance platform, TAK-101 is a potential first-in-class treatment targeting the aberrant immune response in celiac disease, a serious autoimmune disease where the ingestion of gluten leads to inflammation and damage in the small intestine. [joint companies press release, Oct 22, 19] ... COUR is set to receive up to $420 million in future payments and royalties on sales of any marketed products resulting from the licence. [Richard Staines, pharmaphorum.com, Oct 23, 19]
Intrepida Bio (San Diego, CA; no SBIR) debuts as a company dedicated to the discovery and development of medicines that modulate the innate immune system to fight cancer and other diseases. An initial $9.5 million equity investment will fund investigational new drug (IND) application-enabling studies of Intrepida’s lead oncology program. [company press release, Oct 2, 19]
GTX Medical (Dutch and Swiss) is merging with NeuroRecovery Technologies (San Juan Capistrano, CA; no SBIR), a pre-revenue device developer the companies announced. [Dana Elfin, medtechdive.com, Oct 22, 19] Two companies focused on restoring movement and the ability to walk in patients with paralysis and spinal cord injuries [Conor Hale, Fierce Biotech, Oct 22, 19]
Seattle Genetics up 15% [Oct 21, 19] announced positive topline results from the HER2CLIMB trial, a randomized, double-blind, placebo-controlled, active comparator pivotal trial evaluating tucatinib. [company press release, Oct 21, 19]
Verseau Therapeutics (Bedford, MA; no SBIR) launched with $50 million in financing [to develop] novel, first-in-class immunotherapies that target modulation of macrophages, the master orchestrators of the immune system. ... will support advancement of Verseau’s macrophage checkpoint modulator (MCM) programs to the clinic. [company press release, Oct 21, 19]
biotech ReadCoor (Cambridge, MA; SBIR) raised $26.8M in equity according to an SEC filing. [Rowan Walrath, BostInno, Oct 21, 19] we envision swifter scientific discoveries, disease diagnosis and drug development from sequencing reads enhanced by panomic spatial data. [company website]
Biz .gov website folds. As of Nov. 12, 2019 Federal Business Opportunities, the website for publishing all public government procurements, will be officially decommissioned. After Veterans Day, the authoritative source for federal solicitations will be under a page on beta.SAM.gov. [Arran Boyd, nextgov.com, Oct 21, 19]
Dermira up 26% [Oct 18, 19] announced that detailed primary results from its Phase 2b dose-ranging study of lebrikizumab are being presented during the 39(th) Annual Fall Clinical Dermatology Conference in Las Vegas, NV. Lebrikizumab is currently being evaluated in a Phase 3 program in adult and adolescent patients with moderate-to-severe atopic dermatitis. [company press release, Oct 17, 19]
The Defense Innovation Unit has released solicitations through Oct. 27 for a multidomain tactical communications system and dismounted assured positioning, navigation and timing platform. Solicitation. [govconwire.com]
Hepion Pharmaceuticals (formerly ContraVir Pharmaceuticals, Edison, NJ; no SBIR) up 43% [Oct 17, 19] focused on the development of therapeutic drugs for the treatment of liver disease arising from non-alcoholic steatohepatitis ("NASH") and chronic viral infection, today announced that the peer-reviewed Journal of Pharmacology and Experimental Therapeutics has published Hepion's research article entitled, "A Pan-Cyclophilin Inhibitor, CRV431, Decreases Fibrosis and Tumor Development in Chronic Liver Disease Models." The study presents findings on CRV431 that highlight its potential as a drug candidate for chronic liver diseases. [company press release, Oct 16, 19]
Syros Pharmaceuticals down 31% [Oct 17, 19]
Ipsen (France) and Blueprint Medicines (Cambridge, MA; no SBIR) announced Ipsen, through its subsidiary Clementia Pharmaceuticals, and Blueprint Medicines have entered into an exclusive, worldwide license agreement for the development and commercialization of BLU-782, an oral, highly selective investigational ALK2 inhibitor being developed for the treatment of fibrodysplasia ossificans progressiva (FOP). [joint companies press release, Oct 16, 19]
Azitra (Framington, CT; $1.8M SBIR), a microbiome company developing treatments for serious skin conditions, raised a $14 million Series A financing [to] expand its management team and begin clinical testing of its experimental medical dermatology products. [Frank Vinluan, xconomy.com, Oct 18, 19]
Editas Medicine began a collaboration with Asklepios Biopharmaceutical (RTP, NC; $3.2M SBIR) to explore gene-editing medicines for neurological diseases. No financial terms were disclosed. [Frank Vinluan, xconomy.com, Oct 18, 19]
biotech Plexium (San Diego,CA; no SBIR) is the latest addition to the growing number of startups aiming to use technology to devise new drugs that can target those currently “undruggable” proteins. The new company, which debuted Thursday, has attracted $28 million in venture financing from investors that believe in its approach, which involves taking advantage of a built-in cellular mechanism known as protein degradation—the process by which cells recycle misfolded or otherwise damaged proteins. [Sarah de Crescenzo, xconomy.com, Oct 17, 19]
Looking downish. "Pressure on economic activity should intensify in the coming months," says Julian Evans-Pritchard, economist at Capital Economics. "Cooling global demand will continue to weigh on exports, fiscal constraints mean that infrastructure spending will wane in the near-term and the recent boom in property construction looks set to unwind." [Jeff Sparshott, Wall Street Journal, Oct 17, 19]
House committee approved with bipartisan support a measure to protect federal scientists and the data they collect from political influence, with proponents saying it would insulate public servants from undue pressures that could compromise their work. The Scientific Integrity Act (H.R. 1709) would prevent agency officials from interfering with scientific research, including through putting their thumbs on the scale of findings or blocking the distribution of data or public communications. [govexec.com] Trumpism's business obsession went too far for comfort in supressing legitimate and apolitical government science.
Achillion Pharma up 72% [Oct 16, 19] Alexion Pharmaceuticals reached a deal to acquire Achillion Pharmaceuticals for $930 million, pending Achillion shareholder and regulatory approval.[Connor Smith, Barron's, Oct. 16, 2019]
Aethlon Medical (San Diego CA; $600K SBIR) up 72% [Oct 16, 19] announced a 1-15 reverse stock split [company press release, Oct 16, 19]
GC Pharma, a manufacturer of influenza vaccines with a global reach, is partnering with Vaxess Technologies (Cambridge, MA; $3M SBIR, founded 2012), a biotech developing the MIMIX smart release patch. They'll work to commercialize Vaxess' flu vaccine patch. [Srividya Kalyanaraman, BostInno, Oct 16, 19] total funding $20M [crunchbase.com]
Reata Pharmaceuticals (Dallas, TX; one SBIR) which kicked things off Oct. 10 with the announcement that it would end its nine-year partnership with AbbVie. This move allows Reata to reclaim the exclusive rights to two drugs in late-stage clinical trials, as well as next-generation drugs that use the same mechanism. Days later, Reata surprised much of Wall Street with positive results from a pivotal clinical trial for omaveloxolone (omav) as a treatment for Friedreich's ataxia, a neuromuscular disease with no approved treatment options. The stock surged 60% following the announcement, adding roughly $1.5 billion to the company's valuation. [David Haen, Motley Fool, Oct 16, 19]
ArsenalBio (South San Francisco, CA; no SBIR) is launching with an $85 million Series A round of funding. ... is developing technology that adds capabilities to a cell therapy similar to the way a software programmer stacks new functions on a computer program. Improving the way a therapy finds its cancer target is one way Arsenal could “program” a cell, [CEO]Drazan says [Frank Vinluan, xconomy.com, Oct 17, 19]
Medical device company Abilitech Medical (Minneapolis, MN; $240K SBIR) won the Minnesota Cup’s Grand Prize on Monday night, securing $50,000 to grow its business. Abilitech landed an additional $25,000 as the competition’ top women-led startup. Prior to Monday night’s finale, Abilitech received $30,000 for winning the Cup’s Life Sciences/Health IT division. This brings the company’s total MN Cup winnings to more than $100,000. Abilitech is creating a device that helps restore mobility to people with upper-limb and neuromuscular conditions. The wearable device fits to the arm, and like a vehicle’s power steering, requires a small percentage of power from the patient to enable a functional range of motion. Abilitech says the device itself is lightweight, easy to use and comfortable. [Maddy Kennedy, MinneInno, Oct 15, 2019]
Tetraphase Pharma up 16% [Oct 15, 19]
Cesca Thera down 20% [Oct 15, 19]
Cyteir Therapeutics (Cambridge, MA; $2.2M SBIR, founded 2012) Adds $40M for Clinical Test of “Synthetically Lethal” Cancer Drug ... has $40.2 million more in cash to support early-stage tests of a drug intended to treat cancer by targeting a tumor repair mechanism. [Frank Vinluan, xconomy.com, Oct 15, 19] prior funding $36M [crunchbase.com]
OpenAI’s robotic hand Dactyl learned to solve a Rubik’s cube with one hand, achieving a new level of dexterity. It managed to solve the cube even under conditions it hadn’t been trained for, such as while wearing a rubber glove, or while being prodded by a stuffed toy giraffe. Read the story. [Karen Hao, MIT Tech Review, Oct 15, 19]
Trying to understand big economic events by studying the data alone, is like trying to understand a religious awakening by looking at the cost of printing religious tracts. [Robert Shiller, Narrative Economics, 2019]
Strangling the golden goose. The trade war between the United States and China will reduce global expansion by nearly a percentage point by the end of 2020, according to the International Monetary Fund (The Hill).The global economy is on pace for the weakest growth since the financial crisis, and tariffs are a big reason (The Wall Street Journal). [The Hill, Oct 16, 19]
Oncternal Therapeutics up 31% [Oct 14, 19]
Arcadia Biosciences up 25% [Oct 14, 19] Expanded its cultivation footprint on Hawaii by 3x, from 10 to 30 acres, through partnerships with two new license holders. Archipelago is seeding the new acreage this month and expects to employ both permanent and seasonal staffers locally to execute the research plan involving crop management and harvest of several new varieties. [joint venture press release, Oct 15, 19]
Descartes Labs (spinout from Los Alamos NL, Santa Fe, NM; $1.5M SBIR, founded 2014) announcing that it has closed a $20 million round of funding [Ingrid Lunden, techcrunch.com, Oct 11, 19] prior funding $38M [crunchbase.com]
Garwood Medical Devices (Buffalo, NY; no SBIR) received a $500K investment from the Western New York Impact Investment Fund. ... makes devices that reduce infection and promote wound healing after joint replacement surgery. ... through an exclusive licensing agreement, uses patented electrical stimulation technology developed at the University at Buffalo [Matt Glynn, Buffalo News, Oct 11, 19]
Vir Biotech (San Francisco, CA; no SBIR) down 30% [Oct 10, 19] after raising $142M in IPO [company press release, Oct 10,19]
Navy experimenting fast SBIR with five page proposals, two-week decision, fast start, fast stop Technology Acceleration solicitation. Great idea if competitiveness and fairness can be maintained. Read Navy Plan.
Five Prime Therapeutics will eliminate approximately 70 positions across all functions. ... is reaffirming its financial guidance and anticipates ending 2019 with $148 to $153 million in cash, cash equivalents and marketable securities. [company press release, Oct 10, 19]
Apple is the world’s single greatest direct cause of inequality. This claim is not polemical, but statistical: Apple redistributes more wealth upward than any corporation or country on the planet. [Robert Homan, Boston Review, Oct 11, 19] Wealth concentration like that in the late 19th century inspired anti-trust laws that broke up economic empires.
Ra Pharmaceuticals up 101% [Oct 10, 19] UCB (Belgium) and Ra Pharmaceuticals (Cambridge, MA; no SBIR) announced their entry into a merger agreement pursuant for which UCB will acquire Ra Pharma [in] a transaction value of approximately $2.1 billion [joint companies press release, Oct 10, 19]
Aruna Bio (Athens, GA; no prior SBIR, founded 2003), a leader in the development of neural exosomes for the treatment of neurodegenerative diseases, announced the company has been awarded a $4.5 million [NIH SBIR] to support research and development leading up to an Investigational New Drug (IND) application for the use of neural stem cell-derived extracellular vesicles (“neural exosomes”) for the treatment of acute ischemic stroke. [company press release, Oct 10, 19] prior funding $24M [crunchbase.com]
Federal agencies fail, on average, 24 percent of the time to notify applicant small businesses of award decisions within required deadlines. A small business has a zero percent chance of being able to plan to start an innovation project within six months if they apply to ARPA-E or the Defense Threat Reduction Agency, both of which never met the deadline. These competitiveness-throttling facts were uncovered in the latest SBIR-related report from the General Accounting Office (GAO), released Sept. 26. “Small Business Innovation Programs: Many Agencies Took Longer to Issue Small Business Awards than Recommended,” reports only 13 of the 28 federal agencies, offices and components included in the analysis were able to make timely awards (within 180 days) more than 50 percent of the time. [SSTI, Oct 10, 19] Considering the Trumpian federal government upheaval, where's any surprise?
Five Prime Thera up 18% [Oct 9, 19]
Catabasis Pharma up 16% [Oct 9, 19]
Mallinckrodt (UK) announced top-line results from a pivotal Phase 3 trial of StrataGraft, an investigational regenerative tissue developed by the company’s subsidiary Stratatech (Madison, WI; $24M SBIR). The life sciences firm said the 71-patient study met both of its primary endpoints in testing the efficacy and safety of a single application of StrataGraft in treating deep, partial-thickness thermal burns. [Jeff Engel, xconomy,com, Oct 9, 19]
Adaptive Phage Therapeutics ( Gaithersburg, MD; no SBIR) landed $7M in fresh capital as it looks to protect people from superbugs. The investment was led by Alexandria Venture Investments and an undisclosed public life sciences company and health care provider. The fresh capital is earmarked for APT's phase 2 clinical trials for PhageBank, its therapy that uses viruses to kill antibiotic-resistant bacteria. [Kieran McQuilkin, DCInno, Oct 9, 19]
ImmunoMolecular Therapeutics (Boston, MA; $200K SBIR) a clinical-stage company developing personalized therapies for autoimmune disease, raised $10M in Series A financing [Rowan Walrath, BostInno, Oct 9, 19]
Trump removed the gate guards, the Tukish Army stormed in shooting, and Trump has not yet mentioned his threat to destroy Turkey's economy.
Advanced Scanners (Austin, TX; no SBIR) making a 3D optical vision platform to track brain movements during brain surgery, announced it has raised a $1.5 million seed round. [AustinInno, Oct 7, 19] Surgical navigation systems rely on the patient’s preoperative MRI to guide the surgeon during surgery. BUT the brain is continuously changing shape during the procedure. The FDA recently warned surgeons that errors in surgical navigation systems are causing patient deaths, serious or life-threatening injuries, failed, aborted or prolonged medical procedures. [company website]
510 Kardiac Devices (Atlanta, GA; no SBIR) medical tech startup that designs cardiovascular devices cardiologists can use to perform procedures to targeted locations within the structures of the heart, raised nearly $3 million of a $3.5 million round, according to a filing with the SEC. [Madison Hogan, AtlantaInno, Oct 1, 19]
U.S. small-businesses optimism has fallen sharply since last summer as owners become unsettled over trade policy, the path for interest rates and the economic outlook. The National Federation of Independent Business's optimism index remains historically elevated but companies appear increasingly cautious. “All indications are that owners are eager to do more, but they’re uncertain about what the future holds and can’t find workers to fill the jobs they have open,” NFIB President Juanita Duggan said. [Jeff Sparshott, Wall Street Journal, Oct 8, 19]
If SBIR managers seen pre-occupied. As Congress continues to widen its net for documents and testimony, employees subject to conflicting demands have two options, legal experts told Government Executive. The first is to violate orders from management and give Congress what it wants, assuming protections under whistleblower law. A second possibility is to exercise federal employees’ statutory “right to disobey” orders that violate laws, rules or regulations. [govexec.com, Oct 8, 19] Not your rice bowl, but the Constitution does say that each house of Congress shall make its own rules. The President has no voice in that. Concepts like presumption of innocence, questioning accusers, trail of evidence, and trial by jury apparently do not apply.
Need a fact check in the insta-world? Some sources.
Akcea Thera (Cambridge, MA; no SBIR) up 31% [Oct 7, 19], a majority-owned affiliate of Ionis Pharmaceuticals. and Pfizer announced that the companies have entered into a worldwide exclusive licensing agreement for AKCEA-ANGPTL3-L(Rx) , an investigational antisense therapy being developed to treat patients with certain cardiovascular and metabolic diseases. Akcea and Ionis will receive a $250 million upfront license fee, which will be split equally between the two companies. Akcea will settle its $125 million obligation to Ionis in Akcea common stock. The companies are also eligible to receive development, regulatory and sales milestone payments of up to $1.3 billion and tiered, double-digit royalties on annual worldwide net sales following marketing approval of AKCEA-ANGPTL3-L(Rx) [joint companies press release, Oct 7, 19]
NGM Biopharma (South San Francisco, CA; no SBIR, founded 2008) down 20% [Oct 7, 19]
Flagship Pioneering, a unique life sciences innovation enterprise, unveiled Cygnal Therapeutics (Cambridge, MA; no SBIR, founded 2017). Cygnal is the first company to develop drugs in the field of exoneural biology, a new understanding of how nerves and neural signaling drive human health and disease. [Flagship press release, Oct 8, 19] With $65 million from Flagship and other unidentified investors [Jonathan Saltzman, Boston Globe, Oct 8, 19]
Omniscient and Omnipotent. if Turkey does anything that I, in my great and unmatched wisdom, consider to be off limits, I will totally destroy and obliterate the Economy of Turkey,” [Trump] wrote [Alexis Simendinger and Al Weaver, DefenseOne, Oct 8, 19]
Arcellx (Gaithersburg, MD; no SBIR) announced it has raised $85 million in an oversubscribed Series B financing [to] advance the Company’s ARC-T + sparX programs, including clinical development of a bivalent BCMA-targeted cell therapy in multiple myeloma, and a CD123-targeted therapy in acute myeloid leukemia. The Series B will also fund earlier stage ARC-T + sparX programs for patients with solid tumors and diseases outside oncology. [company press release, Oct 3, 19]
Tenaya Therapeutics (South San Francisco, CA; no SBIR, founded 2016) announced the successful completion of a $92 million Series B financing [to] to advance and to expand Tenaya’s pipeline and to strengthen the science, capabilities, and intellectual property that provide the foundation for Tenaya’s multi-modality product platforms – Cellular Regeneration, Gene Therapy, and Precision Medicine. ... has raised $142 million since its founding by scientists at the Gladstone Institutes and University of Texas Southwestern Medical Center. [company press release, Oct 3, 19]
Adicet Bio (Menlo Park, CA; no SBIR) focused on the development of allogeneic cell therapies for cancer using innovative gamma delta T cells, announced the completion of an $80 million Series B financing [to] continue to develop our proprietary technology, to enter the clinic in Non-Hodgkin’s Lymphoma and to advance our solid tumor programs. [company press release, Oct 2, 19]
Lantheus Holdings, a leader in the development, manufacture and commercialization of innovative diagnostic imaging agents and products, and Progenics Pharmaceuticals, (Tarrytown, NY; $34M SBIR) an oncology company developing innovative medicines and artificial intelligence to find, fight and follow cancer, announced a definitive agreement for Lantheus to acquire Progenics in an all-stock transaction. [joint companies press release, Oct 2, 19]
ElevateBio (Cambridge, MA) biotechnology holding company, announced it has established and launched HighPassBio, a company dedicated to advancing novel targeted T cell immunotherapies. [Nick Paul Taylor, Fierce Biotech, Oct 1, 2019]
Shares of Minerva Neurosciences fell 28 percent after the company disclosed that a “cyberattack” at one of its contractors delayed enrollment in a Phase 3 trial of its schizophrenia drug roluperidone. Xconomy has more on that drug and its prospects here. [Ben Fidler, xconomy.com, Oct 3. 19]
Vertex Pharmaceuticals and RNA therapeutics developer Ribometrix (Durham, NC; $500K SBIR) announced that the companies have entered into a strategic collaboration to discover and develop novel RNA-targeted small molecule therapeutic candidates for serious diseases. The collaboration will combine Ribometrix’s proprietary discovery platform for identifying and optimizing small molecule therapeutics that modulate RNA function by targeting three-dimensional (3D) RNA structures with Vertex’s scientific, clinical and regulatory capabilities for up to three therapeutic programs, including one ongoing discovery program from Ribometrix. [joint companies press release, Sep 30, 19]NewLink Genetics (Ames, IA; $1.1M SBIR) and Lumos Pharma (Austin, TX; no SBIR) focused on development and commercialization of therapeutics for rare diseases, announced that the companies have entered into a definitive merger agreement. following the closing of the merger, Lumos Pharma will become a wholly-owned subsidiary of NewLink, and NewLink will be renamed Lumos Pharma, [joint companies press release, Sep 30, 19]
Tocagen (San Diego, CA; $500K SBIR) announced a restructuring to focus its resources on the clinical development of Toca 511 and Toca FC ... will reduce its workforce by approximately 65% [company press release, Oct 3, 19]
Cabaletta Bio (Philadelphia, PA; no SBIR) filed to go public to finance early-stage tests of its experimental cell therapies for autoimmune diseases. [Ben Fidler, xconomy.com, Oct 3. 19]
Icosavax (Seattle, WA; no SBIR) announced the launch of the company with a $51 million Series A financing, ... founded on computationally designed self-assembling virus-like particle (VLP) technology developed at the Institute for Protein Design (IPD) at University of Washington School of Medicine ... to advance the company’s first vaccine candidate, IVX-121, for respiratory syncytial virus (RSV) for older adults through Phase 1b clinical studies [company press release, Oct 3, 19]
Pitch, and Catch. The new Air Force SBIR Pitch Days have already met with success and 10 more Pitch Days have been scheduled in 2019. Participants in the Space Pitch Day, scheduled for the first week of November in San Francisco, will be vying for a piece of approximately $40 million in planned awards. Get invited, pitch your story, get an immedite contract. here's how.
The Department of Defense commissioned a pilot study by TechLink of the economic impact of cooperative R&D agreements (CRADAs) at three Defense labs. The study received information on 628 of 645 completed CRADAs from 1996-2018, 168 of which resulted in sales for the lab’s industry partner. Related sales were $8.7 billion, of which $4.9 billion went to the U.S. military, and TechLink’s IMPLAN analysis estimates $3 billion in federal, state and local tax revenues as part of a $23 billion economic impact. Read more. [SSTI, Oct 2, 19]
The one-man government. President Donald Trump has ordered a substantial reduction in the staff of the National Security Council, according to five people familiar with the plans, as the White House confronts an impeachment inquiry touched off by a whistle-blower complaint related to the agency’s work. [JENNIFER JACOBS AND JUSTIN SINK, The Hill, Oct 4, 19]
Aprea Therapeutics (Boston, MA and Sweden; no SBIR) up 32% [Oct 3, 19] focused on developing and commercializing novel cancer therapeutics that reactivate mutant tumor suppressor protein, p53, today announced the pricing of its [IPO] to raise $85M [company press release, Oct 3, 19]
PDS Biotech up 31% [Oct 3, 19] announced a modification of the clinical trial collaboration agreement with a subsidiary of Merck (known as MSD outside the United States and Canada) to evaluate the combination of PDS's lead Versamune(R) -based immunotherapy, PDS0101, with Merck's anti-PD-1 therapy, KEYTRUDA(R) (pembrolizumab), in a Phase II clinical trial. [company press release, Oct 3, 19]
Microbot Medical up 26% [Oct 3, 19]
Catalyst Biosciences up 25% [Oct 3, 19]
Viela Bio up 23% [Oct 3, 19]
ControlRad (Atlanta, GA; no SBIR) with a focus on reducing radiation exposure during fluoroscopically guided procedures, raised $15M in a Series B round l[to] fuel the commercial launch of ControlRad's Trace system. [Madison Hogan, AtlantaInno, Oct 3, 19]
Marquette University has announced longtime Cree CEO, Chuck Swoboda, as the college’s first “Innovator-in-Residence.” [WisconsinInno, Oct 3, 19]
Political science, again. Climate science, under attack. The Guardian: "The treatment of science by the Trump administration has hit a 'crisis point' where research findings are manipulated for political gain, special interests are given improper influence and scientists are targeted for ideological reasons, a nonpartisan taskforce of former government officials has warned." Read the report, released Thursday by the National Task Force on Rule of Law and Democracy. [DefenseOne, Oct 3, 19]
Tetraphase Pharma down 20% [Oct 2, 19]
FLIR Systems announced that it has acquired the intellectual property and certain operating assets of Aria Insights (previously known as CyPhy Works, founded in 2008 by iRobot co-founder Helen Greiner, $1.2M SBIR) Terms not disclosed. [Robotics Business Review, Oct 2, 19]
Thinking Robot Studios (Canadian medical products maker) plans to open an $84 million plant in Buffalo [NY] that would create more than 88 jobs ... customizes and produces devices using industrial 3D printing, according to New York Power Authority documents. [Matt Glynn, Buffalo News, Sep 26, 19]
startup Relativity Space (Los Angeles, CA; founded 2015) announced that it has closed a $140 million Series C funding round ... has ambitious plans to 3D print the entirety of its rockets, reducing workforce costs and increasing the company's ability to iterate on rocket design [Eric Berger, Ars Technica, Oct 1, 19] prior funding $46M [crunchbase.com]
Foxconn (Chinese) launches $100M smart technology center with University of Illinois [David Schuyler, Milwaukee Business Journal, Oct 2, 19]
Vertex Pharmaceuticals is acquiring Semma Therapeutics (Cambridge, MA; no SBIR) for $950M to advance its diabetes treatment portfolio [Rowan Walrath, BostInno, Oct 2, 19]
Selux Diagnostics (Cambridge, MA; $500K SBIR), developing personalized medicine to treat superbug infections and combat antibiotic resistance, met its first milestone three months ahead of schedule for the milestone-based contract worth up to $45M from the Biomedical and Advanced Research Authority (BARDA). [Srividya Kalyanaraman, BostonInno, Oct 2, 19]
Tariff wars taking their toll. Europe's economy may have ground to a halt. IHS Markit's composite purchasing managers index, a measure of business activity, fell to the lowest level in more than six years as a manufacturing downturn showed signs of spreading into the broader economy..... who is winning the trade war? Tariff and trade experts. Hiring for trade-related roles rose 24% in August. [Jeff Sparshott, Wall Street Journal, Oct 2, 19]
Molecular Assemblies (San Diego, CA; $600K SBIR, founded 2013) announced it has raised a $12.2 million Series A financing [to]to advance the company’s proprietary enzymatic DNA synthesis technology to power DNA-based products in synthetic biology. [company press release, Oct 1, 19] total funding $19M [crunchbase.com]
L'etat, c'est moi. ‘A presidency of one’: Key federal agencies increasingly compelled to benefit Trump [Philip Rucker and Robert Costa, Washington Post, Oct 1, 19] Such focus on the Executive cannot be good for federal programs like SBIR that don't support his big business contributors with legacy profit sources.
Dova Pharmaceuticals (Durham, NC; no SBIR) up 38% [Sep 30, 19] announced it has entered into merger with Swedish Orphan Biovitrum AB (Sobi) ... [for] total potential consideration of up to $915M ... to further accelerate growth in our haematology franchise. There is a large unmet medical need within thrombocytopenia and for us this is a great opportunity to be able to give patients access to new and improved treatments. [company press release, Sep 30, 19]
G1 Therapeutics down 33% [Sep 30, 19] announced preliminary results from a Phase 1/2a dose-escalation study of G1T48, an oral selective estrogen receptor d egrader (SERD) [company press release, Sep 29 19]
BioFactura (Frederick, MD; $3M SBIR, founded 2001) announced a contract awarded by the Biomedical Advanced Research and Development Authority (BARDA) valued at up to $67.4 million for the advanced development of its Smallpox Biodefense Therapeutic as a potential medical countermeasure (MCM) for the treatment of smallpox. [company press release, Sep 26, 19] prior funding $8M [crunchbase.com]
Platelet BioGenesis (Cambridge, MA; $1.9M SBIR), the leader in stem cell-derived, on-demand human platelets (PLTs+™) and genetically engineered platelet-based therapeutics, announced that it has signed a $56 million contract with the Biomedical Advanced Research and Development Authority(BARDA), an agency of the US government's Department of Health and Human Services. PBG will use the funding to develop and establish donor-independent platelets as a medical countermeasure for treating victims of a nuclear or radiological event [company press release,Sep 30, 19] prior funding $40M [crunchbase.com]
Seattle Genetics and Astellas Pharma (Japan) announced initial results from the phase 1 clinical trial EV-103. Forty-five patients were evaluated for safety with the combination of the investigational agent enfortumab vedotin and the immune therapy pembrolizumab in previously untreated patients with locally advanced or metastatic urothelial cancer who were ineligible for treatment with cisplatin-based chemotherapy [joint companies press release, Sep 28, 19]
Beam Therapeutics (Cambridge, MA; no SBIR) seven months after raising $135 million in its series B round, filed to raise up to $100 million in its Nasdaq IPO [Amirah Al Idrus, Fierce Biotech, Sep 28, 19]
Buzzy biotech Moderna is to use its mRNA tech to “explore fundamental immunological processes” with researchers at Harvard. [Ben Adams, Fierce Biotech, Sep 28, 19]
Meissa Vaccines (South San Francisco, CA; $1.5M SBIR, founded 2014) raised $30 million to advance a pipeline of vaccines to prevent viral respiratory infections. The series A equips Meissa to run phase 1 and 2 trials of a respiratory syncytial virus (RSV) vaccine while moving other candidates based on its synthetic biology technology toward the clinic. [Nick Paul Taylor, Fierce Biotech, Sep 26, 19] prior funding $33M [crunchbase.com]
Sherlock Biosciences (Cambridge, MA; no SBIR, founded 2019) has been awarded a multi-year contract [amount unspecified] by the [DOD]'s Threat Reduction Agency to develop a diagnostic tool that leverages CRISPR to detect infectious diseases, bio-threats and other health risks. [company press release, Sep 26, 19] prior funding $48M [crunchbase.com]
Access Vascular (Bedford, MA; no SBIR, fouded 2015), a medical device company developing the next generation of intravenous devices from novel biomaterials designed to minimize the risk of bloodstream infection, catheter thrombosis, and vein trauma, announced $6M in new funding. [company press release, Sep 26, 19] prior funding $9M [crunchbase.com]
Phase Bio up 24% [Sep 25, 19] announced the completion of its Phase 2a clinical trial of PB2452. Full data from the trial are planned to be presented at an upcoming medical congress. In the trial, PB2452 achieved immediate and sustained reversal of ticagrelor in older (ages 50-64) and elderly (ages 65-80) subjects on dual antiplatelet therapy of ticagrelor and low-dose aspirin. PB2452 was generally well tolerated, with only minor adverse events reported. [company press release, Sep 24, 19]
UroGen Pharma down 16% [Sep 25, 19]
Two-year-old biotech Viela Bio (Gaithersburg, MD; no SBIR) has set the terms of its initial public offering, looking to raise about $150M. Viela has said it plans to use the capital to get FDA approval for its first prospective product and to launch it commercially. If all goes well, patients could be using the drug by early next year. [Kieran McQuilkin, DCInno, Sep 25, 19]
“The greatest danger that can befall us in coping with this problem of Soviet communism, is that we shall allow ourselves to become like those with whom we are coping,” George Kennan warned in his Long Telegram from Moscow in 1946, at the dawn of the Cold War [quoted by Alex Pascal, Atlantic Monthly, Sep 24, 19] Trump champions doing just that and recommending [at a major UN speech] that other nations do the same. Such things happen all the time: today's problem was yesterday's solution and now all the people [Kennan's contemporaies like Truman, Acheson, Marshall, FDR] who invented that solution are dead. Trump, as no student of history, and no listener to contrary opinion, heads pell-mell into the new-old 1940s problem.
Amphivena Therapeutics (South San Francisco, CA; no SBIR) private clinical stage immuno-oncology company developing T cell engager therapeutics for cancer, announced today the closing of a $62 million Series C financing [to]to study the therapeutic impact of selective MDSC removal in both hematologic and solid cancers and to advance AMV564 and our novel T cell engagement portfolio to the forefront of immuno-oncology.” [company press release, Sep 24, 19] prior funding $73M [crunchbase.com]
Melinta Thera up 22% [Sep 23, 19]
Cesca Thera up 20% [Sep 23, 19]
Plus Thera down 39% [Sep 23, 19] announced the pricing of an underwritten public offering [to] raise $15M [company press release, Sep 23, 29]
Akcea Thera down 22% [Sep 23, 19] said that CEO and COO have left the company. [xconomy.com, Sep 23,19]
Catalyst Pharm down 20% [Sep 23, 19]
Frequency Therapeutics set IPO terms [to] have an initial market cap of $367M,[Rowan Walrath, BostonInno, Sep 23, 19]
Troubled Massachusetts drugmaker Zafgen plans to lay off 48% of its employees after another setback with its diabetes drug. [Srividya Kalyanaraman, BostonInno, Sep, 23, 19]
Delos Capital (China) announces that it has launched Curamir Therapeutics (Woburn, MA) biotechnology company pioneering micro RNA (miRNA) based cancer therapeutics, with a $10 million Series A financing [Delos press release, Sep 20, 19]
Replimmune up 17% [Sep 20, 19]
Biostage (Holliston, MA;$200K SBIR) developing bioengineered organ implants to treat cancer and other life-threatening conditions of the esophagus, bronchus and trachea, raised $1.3M in equity, according to an SEC filing. [Rowan Walrath, BosontInno, Sep 21, 19] prior funding $16M [crunchbase.com]
Verax Biomedical (Marlborough, MA; $2M SBIR) which specializes in platelet bacterial contamination detection in cells and tissues intended for transfusion and transplantation, raised $2.5M in debt, according to an SEC filing. [Srividya Kalyanaraman, BostonInno, Sep, 19, 19] prior funding $64M [crunchbase.com]
microbiome startup Vedanta Biosciences (Cambridge, MA; no SBIR, founded 2010) raised $8M in equity and seeks to raise an additional $8.6M, according to an SEC filing [Rowan Walrath, BostonInno, Sep 21, 19] prior funding $100M [crinchbase.com]
The small business model in the Defense Department is about looking for new ideas for solving problems, Gen. John Murray, commander of Army Futures Command, said. “I have 37 years in the Army, so I tend to think a certain way; I can guarantee you some of these small startups think about solving problems in an entirely different way.” While the Army can struggle to describe its issues in a way that’s easy for small businesses to understand, the larger issue is a lack of trust that the government can sustain small business models in its current funding process, he said. [AUSA's Five Things, Sep 23, 19] The Army's organizaton for instant war needs new ideas that have been thoroughly tested, can be issued in bulk, and have a logistics system (supply, maintenance, and engineering) backing them up. Fighters cannot abide balky equipment.
Boundless Bio (San Diego, CA; SBIR does not do stealth) came out of stealth mode with an announcement that it had raised a $46.4 million Series A financing round to fund the development of cancer drugs targeting tumors that have what’s known as extrachromosomal DNA. [Sarah de Crescenzo, xconomy.com, Sep 19, 19]
Fujifilm Cellular Dynamics is on the verge of opening a $21 million “cleanroom” facility to manufacture stem cells for use in human clinical trials, the Wisconsin State Journal reported. [Jeff Buchanan, xconomy.com, Sep 18, 19]
ACE-083, an experimental drug from Acceleron Pharma failed a Phase 2 study in facioscapulohumeral muscular dystrophy. With the beta thalassemia drug luspatercept, Acceleron could notch its first drug approval next year. [Alex Lash, xconomy.com, Sep 19,19]
Exagen (Vista, CA; one SBIR) which sells diagnostic blood tests for autoimmune diseases, raised $50 million in an IPO. [Alex Lash, xconomy.com, Sep 19,19]
IGM Biosciences (Mountain View, CA; no SBIR) up 52% [Sep 18, 19] announced the pricing of its [IPO] to raise $175M ... develops antibodies for the treatment of cancer [company press release, Sep 17, 19] prior funding $142M [crunchbase.com]
Zynerba Pharma down 22% [Sep 18, 19] the leader in innovative pharmaceutically-produced transdermal cannabinoid therapies for rare and near-rare neuropsychiatric disorders, announced positive top line results from the open label Phase 2 BELIEVE 1 (Open Label Study to Assess the Safety and Efficacy of Zygel(TM) (ZYN002) Administered as a Transdermal Gel to Children and Adolescents with Developmental and Epileptic Encephalopathy) clinical trial. [company press release, Sep 18, 19]
BioCardia (San Carlos, CA; $240K SBIR) up 25% [Sep 17, 19] announced that the independent Data Safety Monitoring Board (DSMB) has completed its prespecified data review for the Phase III pivotal CardiAMP Heart Failure Trial, which included safety follow-up results on 35 patients and all additional data available on the 50 patients randomized in the trial as of August 31, 2019. The DSMB indicated there were no safety concerns with the CardiAMP study results and recommended that the trial continue, as planned. [company press release, Sep 16, 19]
Plus Therapeutics ($240K SBIR) down 15% [Sep 17, 19]
Ziopharm Oncology (Boston, MA; no SBIR) developing immuno-oncology gene and cell therapies, raised $19.5M in equity, according to an SEC filing. [Rowan Walrath, BostonInno, Sep 17, 19]
H. Lundbeck A/S (Denmark) and Alder Pharmeuticals (Bothell, WA; one SBIR) up 84% [Sep 16, 19] committed to transforming migraine treatment and prevention announced a definitive agreement for Lundbeck to acquire Alder. ... transaction is valued at up to $1.95 billion (approximately DKK 13 billion) net of cash, on a fully diluted basis. [joint companies press release, Sep 16, 19]
Novavax up 20% [Sep 16, 19]
Stereotaxis (St Louis, MO; one SBIR in 1992) up 16% [Sep 16, 19]
Karyopharm Therapeutics announced a royalty agreement with HealthCare Royalty Partners for up to $150 million to support the ongoing development and commercialization of XPOVIOTM (selinexor), the Company’s first-in-class, oral SINE compound, which is currently marketed in the U.S. for the treatment of patients with heavily pretreated multiple myeloma. [company press release, Sep 16, 19]
II‐VI announced that it signed a strategic partnership agreement with LITE-ON Technology, a global leader in optoelectronic components, to partner in the volume manufacturing and commercialization of packaged semiconductor lasers for mass-market light detection and ranging (LiDAR). [company press release, Sep 12, 19]
AgeneBio (Baltimore, MD; no prior SBIR, approx $26M NIH grants, founded 2008) has been awarded nearly $500,000 from the Alzheimer’s Drug Discovery Foundation and has been selected to receive a [NIH] SBIR of up to $2.9 million Both awards go towards the development of a first in class therapeutic in AgeneBio, Inc.’s GABA-A a5 program [company press release, Sep 11, 19] prior funding $10M [crunchbase.com]
Tariffs as politics. President Xi Jinping and top Chinese officials have signaled their willingness to accept some pain at home under U.S. tariffs rather than agree to major concessions. China experts say the political cost to Xi of yielding to Trump could be more damaging than living with the tariffs as Xi seeks to solidify his power in the Communist Party while expanding influence over the world economy (The Hill). World's biggest economy spars with world's biggest population.
10X Genomics (Pleasanton CA; no SBIR, founded 2012) up 35% [Sep 12, 19] after $390M IPO. prior funding $242M [crunchbase.com]
Prevail Thera up 17% [Sep 12, 19]
Evelo BioSciences up 17% [Sep 12, 19]
Tocagen (San Diego, CA; $500K SBIR) down 77% [Sep 12, 19] announced that the Toca 5 Phase 3, randomized, multi-center clinical trial evaluating Toca 511 & Toca FC in patients with recurrent high grade glioma (HGG) undergoing resection missed the primary endpoint of overall survival compared to standard of care treatment (11.1 months median compared to 12.2 months, HR=1.06, p=0.6154). In addition, all secondary endpoints showed no meaningful difference between the arms of the trial. The safety, tolerability and adverse event profile of Toca 511 & Toca FC was as expected for this patient population. [company press release, Sep 12, 19]
Catalyst Pharma down 17% [Sep 12, 19]
I am enough of an artist to draw freely upon my imagination. Imagination is more important than knowledge. Knowledge is limited. Imagination encircles the world. [Albert Einstein, 1929]
Nido Biosciences (Boston, MA; no SBIR) raised $4M in equity, according to an SEC filing (Rowan Walrath, BostInno, Sep 11, 19].
Yes today, no tomorrow. President Trump told his advisers that he doesn’t plan to try to bypass Congress and lower capital-gains taxes by indexing gains to inflation, according to three people familiar with the matter. [Wall Street Journal, Sep 11, 19] More important, who would invest where government policy and leaders change at the whim of the executive? Trump disdains our stable government structure wherein law determines the policies and Congress approves the Executive Branch leaders.
Acorda Thera up 27% [Sep 10, 19]
Immunomedics up 17% [Sep 10, 19]
Arcadia Biosciences (Davis, CA) said it raised $9.2 million from a direct offering of its stock to institutional and accredited investors. [Mark Anderson, Sacramento Business Journal, Sep 10. 19]
The Alzheimer's Drug Discovery Foundation (ADDF) has awarded $500,000 to AgeneBio (Baltimore. MD; at least $3M SBIR) to accelerate the first-in-class therapeutic to the clinical stage $2.9 million over 3.5 years from the National Institute on Aging (NIA), adding to the ~$11M of prior NIH investment in this innovative therapeutic program provided through the NIA's AD Drug Development Program and the NIH Blueprint Neurotherapeutics Program. [company press release,, Sep 11, 19]
Holos (Madison, WI; founded 2015) software startup just landed its second contract from the U.S. Air Force to make virtual reality and augmented reality training programs. Holos announced that it has received a $750,000 Phase II SBIR contract with the Air Force. Holos said it will help the Air Force develop VR maintenance and repair training programs. It will also develop a prototype for the Air Force’s Multi-Domain Command Control system. Holos creates VR and AR education software for classrooms, giving teachers and students the ability to create, organize and learn in 3D. For its Air Force applications, the technology is largely the same, but loaded with different content, the company told Wisconsin Inno earlier this year. Holos likens its product to a 3D version of Powerpoint. [Jim Dallke, WisconsinInno, Sep 5, 19] What's the SBIR problem here: What is SBIR for? Like almost every software contract, the contractor can certainly do what it proposes: a sound engineering job by competent engineers. The bureaucratic question for software SBIR is not technical mysteries, but will anyone buy the product - a question best left to ordinary investment and R&D programs. But with agency authority to fund any R&D thing they want with SBIR, mission agencies chose utility while both agency and company claim innovation.
Advisors beware. Regardless of who has advised Mr. Trump on foreign affairs — generals and corporate tycoons, seasoned pros and amateurs — all have proved powerless before a zest for chaos that would have thwarted George Marshall. [NYTimes ediotrial, Sep 11, 19] Trump Rule: When I want your opinion, I'll tell you what it is. Trump will have trouble finding a Kissinger for his Nixon, because as David Graham (WashPo) notes: The problem is not that Trump failed to get along with John Bolton—it's that he doesn't want a national security adviser in the first place.
ACADIA Pharma up 63% [Sep 9, 19] announced that its Phase 3 HARMONY study, a double-blind, placebo-controlled relapse prevention trial evaluating pimavanserin for the treatment of dementia-related psychosis, met its primary endpoint, demonstrating a highly statistically significant longer time to relapse of psychosis with pimavanserin compared to placebo in a planned interim efficacy analysis. [company press release, Sep 9, 19]
Cesca Thera up 17% [Sep 9, 19]
Ardalyx up 15% [Sep 9, 19]
Frequency Therapeutics (Woburn, MA; no SBIR) biotech focused on degenerative diseases, filed to raise $100M in an IPO. It has yet to post a revenue and posted losses of $19.2M last year [Srividya Kalyanaraman, BostonInno, Sep, 9, 19]
Aprea Therapeutics (Boston, MA ans Sweden; no SBIR) biotech focused on cancer therapies, filed to raise $86M in an IPO. It has yet to post a revenue and posted losses of $15.5M in 2018 [Rowan Walrath, BostonInno, Sep, 9, 19]
Platelet BioGenesis (Cambridge, MA; no SBIR) which develops stem cell-derived, on-demand human platelets and platelet-based therapeutics, closed more than $26M in Series A-1 financing. [Rowan Walrath, BostonInno, Sep, 9, 19]
Bio2 Technologies (Woburn, MA; no SBIR) raised about $4.3M as it continues with a clinical trial of its Vitrium resorbable orthopedic biomaterial for musculoskeletal surgery. It seeks to raised about $2.2M more, according to an SEC filing. [Srividya Kalyanaraman, BostonInno, Sep, 9. 19]
Biotech startup Trucode Gene Repair (South San Francisco, CA; no SBIR) announced that it is advancing its next-generation in vivo gene editing technology to correct mutations that cause sickle cell disease, cystic fibrosis, and other devastating genetic disorders. With $34 million from investors, Trucode has now emerged from stealth-mode after establishing a broad and exclusive intellectual property estate for its triplex gene editing technology, assembling a cohesive team of industry veterans, and identifying lead candidates in multiple clinical indications. [company press release, Sep 10, 19]
Plant science company ZeaKal (San Diego, CA; no SBIR, founded 2010) said it closed a $15 million Series C financing round to advance its PhotoSeed technology, which increases crop yield by increasing a plant’s capacity for photosynthesis. [Sarah de Crescenzo, xconomy.com, Sep 10, 19]
Vical (San Diego, CA; $13M SBIR, founded 1987) stockholders late last month OK’d a reverse merger with Brickell Biotech (NASDAQ: BBI). ... was developing treatments for life-threatening infectious diseases, including antiviral and antifungal compounds, announced in June that it planned to become part of Brickell (Boulder, CO; no SBIR) developing drugs for skin diseases. [Sarah de Crescenzo, xconomy.com, Sep 10, 19]
Microbot Medical (Hingham MA; no SBIR) up 44% [Sep 6, 19] will demonstrate a working prototype of the Company's Self-Cleaning Shunt (SCS(TM)). [company press release, Sep 5, 19]
Applied Genetic Technologies up 17% [Sep 6, 19]
Phase BioPharma down 19% [Sep 6, 19]
Plus Thera down 15% [Sep 6, 19]
OpGen is acquiring German molecular diagnostic company Curetis in a move that will create a combined firm worth $24M. OpGen, a precision medicine developer, will make Curetis a wholly owned subsidiary [DCInno, Sep 5, 19]
Adaptive BioTech down 17% [Sep 5, 19]
Plus Thera down 16% [Sep 5, 19]
Veralox Therapeutics (Frederick, MD; $300K SBIR, founded 2017) a preclinical stage company focused on accelerating the development of first-in-class therapeutics for unmet medical needs, announced it has raised a $5.4 million seed funding round. [company press release, Sep 5, 19]
OpGen up 23% [Sep 4, 19]
Immunic down 17% [Sep 4, 19]
Ardelyx down 15% [Sep 4, 19]
Repare Therapeutics (Cambridge, MA and Canada; no SBIR) raised an $82.5 million series B round to take synthetic lethality drugs into humans. [company press release, Sep 4, 19]
Vertex Pharmaceuticals announced a definitive agreement under which Vertex will acquire Semma Therapeutics (Cambridge, MA; no SBIR), pioneering the use of stem cell-derived human islets as a potentially curative treatment for type 1 diabetes, for $950 million in cash. [Vertex press release, Sep 3, 19]
Selecta Biosciences (Watertown, MA; $200K SBIR, founded 2007) raised $5.8M in equity, according to an SEC filing. [Srividya Kalyanaraman, BostonInno, Sep, 4. 19]
Sofregen (Medford, MA; no SBIR) raised $8.1M in equity, according to an SEC filing. [Srividya Kalyanaraman, BostonInno, Sep, 4. 19]Curamir Therapeutics [Woburn, MA; no SBIR) raised $5.2M in equity and seeks to raise an additional $5M, according to an SEC filing. [Rowan Walrath, BostonInno, Sep, 4. 19]
Ardelyx (Fremont, CA; no SBIR) up 71% [Sep 3, 19], a specialized biopharmaceutical company focused on developing first-in-class medicines to improve treatment for people with cardiorenal diseases, reported positive results from AMPLIFY, a pivotal Phase 3 study of tenapanor in combination with phosphate binders in patients with chronic kidney disease (CKD) on dialysis whose hyperphosphatemia was not previously controlled with binders alone. [company press release, Sep 2, 19] total funding $300M [crunchbase.com]
Liquidia Tech down 19% [Sep 3, 19]
Mirum Pharmaceuticals down 21% [Sep 3, 19] reported financial results for the quarter
PhaseBio Pharmaceuticals down 15% [Sep 3, 19]
drug developer Viela Bio (Gaithersburg, MD; SBIR) filed to go public with a $150M IPO, just more than a year after spinning out from MedImmune. [Kieran McQuilkin, DCInno, Sep 3, 19]
Uncoupling. Instead of giving in to Mr. Trump’s demands, Huawei recently introduced its own operating system, Harmony, an alternative to Android that will reduce Huawei’s reliance on U.S. technology. ...the president’s erratic approach has aggravated the situation by encouraging Mr. Xi to embrace decoupling on his own terms. [Stephen A. Myrow, Wall Street Journal, Sep 3, 19] Meanwhile, President Trump said that Chinese manufacturing would “crumble” if the country did not agree to the United States’ trade terms, as newly released data showed his trade war was washing back to American shores and hurting the factories that the president has aimed to protect. [Ana Swanson, New York Times, Sep 3, 19] Trump marches boldly at the head of the America Alone parade, apparently without looking over his shoulder to see who is following.
Tax cuts were once critical to the Republican Party’s electoral success. Now, polling data show that few Americans believe taxes are the most important issue facing the nation. [Jackson Gode and Vanessa Williamson, Brookings, Sep 3, 19] Which means that Trump and the Republican Congress got away with their tax cuts for the wealthy, nothing for the middle and lower echelons, and a big national debt increase, all justified by a fantasy supply-side economics argument. Now the Republicans will shift back to the case for cutting public spending benefitting the undeserving unwealthy.
OpGen (Gaithersburg, MA; no SBIR) up 18% [Aug 30, 19]
Sonavex (spun out of Johns Hopkins, Baltimore. MD; $1.2M prior SBIR) medical device company announced a $3 million [NIH] Phase II SBIR to use its EchoMark & EchoSure devices to support arteriovenous (AV) fistula maturation and long-term viability. ... for prospective clinical studies and continued [R&D]. [company press release, Aug 29, 19] prior funding $10M [crunchbase.com]
Agilvax (Albuquerque, NM; $2.6M SBIR, founded 2011) raises millions, names new CEO [Albuquerque Business Journal, Aug 29, 19] prior funding $8M [cruchbase.com]
A team led by Dynetics (Arlington, VA and Huntsville, AL; at least 30 SBIRs) technical solutions business will develop prototypes of the Common-Hypersonic Glide Body system under a potential three-year, $351.6M other transaction agreement with the U.S. Army. Dynetics said it will work with Lockheed Martin, Raytheon, and General Atomics’ electromagnetic systems business on the C-HGB prototype development project. [Jane Edwards, GovConWire, Aug 30, 19]
There are twice as many workers over age 60 as there are under 30. [Courtney Buble, GovExec, Aug 30, 19] Fresh blood needed; please ignore the current President's rantings and sign up for the long haul of successive presidents and reasonably stable laws.
Is nothing sacred? President Trump appears to have taken the highly unusual step of releasing an official and relatively high resolution annotated U.S. intelligence image. [New York Times, Aug 30, 19] A gift for all those enemies out there who did not know how good our satellite vision is. Yet simultaneously excoriating an FBI head who sought outside advice about sensitive but unclassified information in a difficult political situation. The bottom line: who is not with me is against me.
Who me, wrong? President Trump rejected the notion that his trade policies were having a negative impact on the U.S. economy, instead blaming “badly run and weak companies” for any business setbacks. [Wall Street Journal, Aug 30, 19]
LogicBio Therapeutics (Cambridge MA; no SBIR) up 29% [Aug 29, 19]
Esperion (Ann Arbor, MI; no SBIR, founded 2008) announced positive top-line results from the Phase 2 bempedoic acid / ezetimibe combination tablet study (1002-058). This was a randomized, double-blind, parallel group study assessing the efficacy and safety of the bempedoic acid / ezetimibe combination tablet compared to ezetimibe and placebo in 179 patients with both hypercholesterolemia and type 2 diabetes. Patients enrolled were on stable background diabetes medications and washed out of lipid modifying therapies. [company press release, Aug 29, 19] total funding $245M [crunchbase.com]
Zogenix, a global pharmaceutical company developing rare disease therapies, announced that it has entered into a definitive agreement to acquire Modis Therapeutics (Oakland, CA; no SBIR, founded 2016) biopharmaceutical focused on developing novel therapies for rare genetic diseases with high unmet medical need. Modis’slead product candidate, MT1621, an investigational deoxynucleoside substrate enhancement therapy,is in late-stage development for the treatment of Thymidine Kinase 2 deficiency (TK2d) .... Modis will receivean upfront payment of $250 million, comprised of $175millionin cashand $75 million in Zogenixcommon stock. Modis is also eligibleto receive additional milestone payments consisting of $100 million upon receipt of [FDA] napproval of MT1621in the U.S. and $50 million upon European Medicines Agencyapproval in Europe. Zogenix will also paya5%royalty on any future net salesof MT1621. [Zogenix press release, Aug 29, 19] Modis $30M Series A in 2018
Not leaving China. according to a survey of U.S.-China Business Council members, 87% said they neither have moved nor plan to shift operations out of China, compared with 90% in a 2018 survey. Only 3% said their China operations were unprofitable, unchanged from a year ago. [Jenny Leonard, Bloomberg News, Aug 29, 19]
Reversal. The .gov now says that children born to US military and USG employees overseas will still be automatically US citizens if the parent is.
Plus Therapeutics up 29% [Aug 28, 19]
PhaseBio Pharma up 17% [Aug 28, 19]
Ionis Pharma (Carlsbad, CA; at least $4M SBIR) announced that GSK exercised its option to license Ionis' antisense medicines for people with chronic hepatitis B virus (CHB) infection following positive Phase 2 results. CHB is a chronic viral infection of the liver that can lead to significant and potentially fatal health conditions, including cirrhosis, liver failure and liver cancer. Current treatments for patients with CHB provide low levels of hepatitis B virus S antigen seroclearance, leaving many patients without a treatment to achieve sustained disease remission. There are more than 200 million patients worldwide living with CHB. [company press release, Aug 27, 19]
Slippery Slope. Trump said he'll pardon U.S. government employees who break laws [seize private land and disregard environmental rules] while working on border barriers, the Washington Post reports. [Defense One, Aug 28, 19]
Miromatrix Medical (Eden Prairie, MN; $600K SBIR), whose long-term goal is to grow human organs using a patient’s own cells, has spun off a portion of its business to create a new startup. ... transferred to Reprise Biomedical, the new business, two existing, FDA-cleared medical devices – Miromesh and Miroderm. Miromesh reinforces soft tissue and is used during plastic and reconstructive surgery, while Miroderm is used for managing wounds. [Maddy Kennedy, MinneInno, Jul 1, 19]
Discouraging military and diplomtic service. Trump administration said that children born to U.S. military members and government employees working overseas will no longer automatically be considered United States citizens. [Morgan Chalfant, The Hill, Aug 28, 19]
Zero meets 12000. “No, I don’t think this president has lied,” she [campaign spokesperson Kayleigh McEnany] told Cuomo, before repeatedly backing the honesty of Trump, who has given more than 12,000 false or misleading statements during his presidency, according to The Washington Post’s Fact Checker. [Timothy Bella, WashPo, Aug 28, 19]
Plus Therapeutics up 42% [Aug 27, 19]
Arcadia Biosciences down 23% [Aug 27, 19]
Arcadia Biosciences up 52% [Aug 26, 19] announced a binding term sheet agreement with Arista Cereal Technologies and Bay State Milling Company for commercialization of its high fiber resistant starch wheat in key wheat markets, including North America, Europe and parts of Asia. [company press release, Aug 26, 19]
Plus Therapeutics up 27% [Aug 26, 19]
Salarius Pharma (Houston, TX; no SBIR) up 21% [Aug 26, 19] The Ivy Brain Tumor Center at the Barrow Neurological Institute and Salarius Pharmaceuticals announced a collaborative partnership to test Salarius' therapeutic candidate, Seclidemstat, for the treatment of glioblastoma. The organizations will launch what they believe is the most comprehensive pre-clinical study to date, evaluating the effect of targeting LSD1 (lysine-specific histone demethylase 1A), a key enzyme that has increased expression in tumors of brain cancer patients. [joint press release, Aug 26, 19]
UES {Dayton, OH; tons of SBIR) won a potential eight-year, $90.3M contract to develop a technology for the U.S. Air Force identify molecular signatures of airmen performance. The company will conduct basic, applied and advanced research on molecular assessment sensing tools and demonstrate signatures in operational environments, the Department of Defense said. [Matthew Nelson, GovConWire, Aug 26, 19]
Taking the Long View. The Fed’s rationale for ignoring Mr. Trump’s pressure campaign is grounded in cold equations. Years of academic research and history show that nations that allow politics to guide interest rates risk more rapid inflation and are prone to painful boom-and-bust cycles. Most of the economics profession sees a monetary policy system free of political influence as an essential precondition for stable growth. [Jeanna Smialek, New York Times, Aug 25, 19]
Progenics Pharma up 17% [Aug 22, 19]
Retrophin (San Diego, CA; no SBIR) down 22% [Aug 22, 19] announced that the Phase 3 FORT Study evaluating the safety and efficacy of fosmetpantotenate compared to placebo in patients with pantothenate kinase-associated neurodegeneration (PKAN) did not meet its primary endpoint and did not demonstrate a difference between treatment groups. The study also did not meet its secondary endpoint. [company press release, Aug 22, 19]
Finch Therapeutics (Somerville, MA; no SBIR, founded 2004), a clinical-stage microbiome therapeutics company, announced the completion of a $53 million Series C financing [to] advance its pipeline of novel microbial therapies, including CP101, a Full-Spectrum Microbiota® (FSM®) therapy delivered in an oral capsule that is designed to contain a diverse community of microbiota and restore a balanced microbiome. [company press release, Aug 22, 19] total funding $95M [crunchbase.com]
Aperiomics (Sterling, VA; SBIR) announced the close of its Series A funding round of $1.8M, taking long strides toward detecting under-diagnosed infections. The startup’s testing kits use genomic sequencing and machine learning to identify pathogens that generally are difficult to diagnose. Doctors send a sample to Aperiomics, which extracts genetic information, identifies the bacteria or virus within the sample and sends back a report. [Kieran McQuilkin, DCInno, Aug 22, 19]
Thumb on the scale. The daily news briefing, which is sent to the [Department of Justice]'s 400-some immigration judges, included a link to a website that has been a known platform for white supremacists. [Reis Thebault, WashPo, Aug 22, 19]
Arcadia Biosiences up 24% [Aug 21, 19]
Harpoon Thera up 20% [Aug 21, 19]
Cree down 16% [Aug 21, 19] as Its Outlook for the Quarter Surprises Wall Street [Barron's, Aug 21, 19]
Rooster Bio (Frederick, MD; $200K SBIR, founded 2012) raises $22M [Baltimore Busiess Journal, Aug 21, 19] prior funding $22M [crunchbase.com]
Oncorus (Cambridge, MA; no SBIR, founded 2015), an oncolytic virus company focused to transform outcomes for cancer patients, announced the completion of an oversubscribed $79.5 million Series B financing. [company press release, Aug 21, 19] prior funding $60M [crunchbase.com]
Enjoy the ride. The federal government will rack up $12.2 trillion in deficits through 2029, according to a new projection from the non-partisan Congressional Budget Office (CBO), an $809 billion increase from its last projection in May. CBO, Congress’s official budgeting scorekeeper, said that the deficits would average 4.7 percent of GDP through the next decade, a significant increase from the 2.9 percent average over the past 50 years. [Niv Elis, The Hill, Aug 21, 19] Economically it means the federal government will spend that much more every year with borrowed money. And since the world is awash in investable cash, there will be little crowding out of private investment by a high cost of private debt. It's a partly Trumpian wonder world if you close your eyes to any eventual demand for debt repayment. It has worked for Trump for decades.
Synlogic (Cambridge MA; no SBIR) down 28% [Aug 20, 19] Synthetic biology startup has stopped development of SYNB1020 after the drug failed to lower blood ammonia levels in a phase 1b/2a trial. The engineered stain of [E-coli] performed no better than placebo in the small trial [Fierce Biotch, Aug 20, 19]
Plus Therapeutics (Cambridge MA; no SBIR) down 22% [Aug 20, 19]
Sarepta Thera (Cambridge MA; no SBIR) down 15% [Aug 20, 19]
Applied Research Associates (Albuquerque, NM; $25M SBIR) won a potential 10-year, $240M contract to provide operational support tools to aid the Defense Threat Reduction Agency in countering risks from weapons of mass destruction. The cost-plus-fixed-fee, indefinite-delivery/indefinite-quantity contract will include research, development, decision support analysis and technical reachback operational support, the [DOD]said. Work will take place at multiple agency-run facilities within Fort Belvoir in Virginia. [Nichols Martin, GovConWire, Aug 20, 19] If SBIR's advocates wanted SBIR to protect local jobs, do they now applaud a company's big contract in Virginia? Will a lot of smart New Mexicans abandon the state for Virginia?
Amyris Biotech (Emeryville, CA; $900K SBIR) up 20% [Aug 19, 19]
Oncternal Thera up 18% [Aug 19, 19]
Plus Therapeutics down 18% [Aug 16, 19]
Siamab Therapeutics (Newton, MA; no SBIR, founded 2006) developing novel glycan-targeted cancer therapeutics, has entered into a strategic agreement valued at up to $202 million with an undisclosed, large commercial-stage biopharmaceutical company under which such company will develop and commercialize antibody-based products targeting a tumor-associated carbohydrate antigen (TACA) identified by Siamab’s proprietary TACA discovery platform. [company press release, Aug 19, 19] prior funding $6.6M [crunchbase.com]
The FDA rejected the new drug application for golodirsen, the follow-up to Exondys 51, Sarepta’s first treatment for Duchenne muscular dystrophy (DMD), the company said in a statement. [Amirah Al Idrus, Fierce Biotech, Aug 19, 19]
Monopar Therapeutics (Wilmette, IL; no SBIR) filed to raise $40 million IPO. [to] start a phase 3 trial of a prophylactic treatment for a side effect of chemoradiotherapy. [Nick Paul Taylor, Fierce Biotech, Aug 16, 19]
Confident but worried. Trump said he is considering measures to bolster the economy [which he lauds in great helth], including a possible [standard trickle-down] reduction in capital-gains taxes, and continued to press the Fed to [huge] cut rates even as he played down warning signs of a possible slowdown. [ Rebecca Ballhaus, Andrew Restuccia, and Richard Rubin, Wall Street Journal, Aug 20, 19]
Solid Biosciences up 43% [Aug 16, 19] reported quarterly financial results
Alpine Immune Sciences up 24% [Aug 16, 19] reported quarterly financial results
Novavax up 18% [Aug 16, 19]
Arcadia Biosciences down 18% [Aug 16, 19] reported quarterly financial results
Jump ahead to next phase. As a result of their August 9, 2019 review, the DSMB recommended that the study be stopped and that all future patients be randomized to receive either REGN-EB3 [from Regeneron] or mAb114 [from Ridgeback BioTherapeutics (Miami. FL, no SBIR, founded 2015)] in what is being considered an extension phase of the study. This recommendation was based on the fact that an early stopping criterion in the protocol had been met. The preliminary results in 499 study participants indicated that those individuals receiving REGN-EB3 or mAb114 had a greater chance of survival compared to those participants in the other two arms. [Ridgeback press release, Aug 12, 19]
IonQ (College Park, MD; no SBIR, funded 2016) is a developer of quantum computing for commercial applications. .. total funding #20M [crunchbase.com] recently reported that its prototype computer, using 11 qubits made of ionized atoms, performed more complex calculations with greater accuracy than any rival machine. [Jeanne Whalen, WashPo, Aug 18, 19]
In designing the plane’s flight controls, the aerospace giant assumed that pilots should be able to sift through a jumble of contradictory warnings and take the proper action 100% of the time within four seconds. That’s about the amount of time that it took you to read this sentence. [Andrew Tangel, Andy Pasztor, and Mark Maremont, Wall Street Journal, Aug 16, 19]
Arcadia Bio up 15% [Aug 15, 19]
Polymath. the first metrologist to use a wave-length of light as a unit of measure, the inventor of the quincuncial projection of the sphere, the first known conceiver of the design and theory of an electric switching-circuit computer. ... fundamental discoveries in science and mathematics: the shape of the Milky Way galaxy; the first precise measurement of the Earth’s gravity and circumference; one of the most accurate and versatile projections of the 3D globe of the Earth onto 2D space; the chemistry of relations and working out the consequences of the discovery of the electron for the periodic table; the axiomisation of the law of the excluded middle, or Peirce’s Law: ((P→Q)→P)→P); existential graphs and the transformation of mathematics into an (quasi-)empirical component of studies on cognition; one of the first studies of the stellar spectra, particularly the spectral properties of argon; the invention of the then most accurate gravimetric pendulum; the first standardisation of the length of the metre by anchoring it to the length of a wavelength of light the most original and the most versatile intellect that the Americas have so far produced - Charles S Peirce (1839-1914),- says the leading Peirce scholar ever, Max Fisch. ... [Daniel Everett, Aeon, Aug 14, 19]
news and views about government programs, politics, attitudes ...1996-1997; 1998; 1999; Y2K; 2001 , 2002-2003 ; 2004-5; 2006; 2007-08 2009-2010; 2011-2012; 2013-14 ; 2015; 2016; 2017-18
BMDO/ MDA including SBIR the doings of star wars
Miscellaneous Stories 1996-1997; 1998-1999; 2000-2001; 2002-2003 ; 2004-5 ; 2006; 2007 2009-2010 ; 2011-2012; 2013-2014; 2015; 2016; 2017
IPO and Venture Markets 1996-1998 .... 1999-2005 ... 2006-present
Quotes steal them if you like
Note: in these old stories, many links are dead, obsolete, or missing
Stories about companies; 1-Al .. Am-Az .. B .. C ... D-E .. F .. G-H .. I-J .. K-L .. M ... N-O ... P ... Q-R .. S1-Se .. ... Sf-Sz .. T-U .... V-Z
10X Genomics ..... 1366
Technologies ... 1st Detect ...
21-Century Silicon ... 21st Century
Systems .... 23andMe ... 24M Technologies
... 30
Second Software ... 360fly ..... 3Bar Biologics .... 3C Semiconductor
... 3DEO .... 3D Glass Solutions ..... 3Dnamics ..... 3D
Robotics .... 3D Systems
..... 3D Technology
Laboratories
.... 3F ... 3iNanotech .... 3PrimiR ...
3Scan ..... 3-V
Biosciences
.... 3VR ... 410 Medical Innovation .... 454 Life Sciences .... 4C
Medical Technologies .... 4D Molecular Therapeutics ..... 4s3
Bioscience ... 5D Robotics
..... 7AC
Technologies ... 89Bio ... 908Devices ... 9Mile Labs
A10 Networks ... A123Systems ... A4 Pharma .... A&G
Pharmaceutical ... Aastrom
Bioscience
.. Abacus Technology ... ... Abaxis .... Abcombi Sciences
.....
Abeona Therapeutics
..... AbGenomicsInternational
... Abiomed ... Ablative Solutions .... Ablexis
...... ABL
Technologies .... Abpro
Therapeutics ..... AbSci .... Absorbent
Materials ... Abundant Robotics ..... AbVitro ...
Acadia Pharma ... Acambis
.. Accel Diagnostics ..... Acceleron Pharma
... Accelrys
... Accentia
BioPharmaceuticals ... Accent Therapeutics ..... Accera ....
Access Pharmaceuticals
...
Access
Scientific .... Accion Systems ..... Accumetrics
... AccuraGen ..... Accurate
Automation
.. Accuray ... Accuri Cytometers
... Acelerox ....
Acelity .... AcelRx
Pharmaceuticals ...
Acera Surgical .... Acer Thrapeutics .... Acetylon
Pharmaceuticals ... Achaogen ... Achates
Power .....
Achillion
Pharmaceuticals ... ACIST Medical Systems .... Acorda
Therapeutics
... Acorn
Cardiovascular ... Acquia .... AcroMetrix
... AcryMed ...
ActaCell ... Actasys .... ACT Biotech ... Active
Power ...
ActivBiotics
... ActivMedia Robotics .... Acton Pharmaceuticals
...
Actuality... Actuate
Therapeutics .... Acucela ... AcuFocus ....
Aculight
...
Acumentrics ... AcuraStem .... Acutus Medical .... Adamas
Pharmaceuticals ......
Adamis Pharmaceuticals
... Adapteva .... Adaptimmune Therapeutics .... Adaptive
Biotechnologies ..... Adaptive
Computing
... Adaptive
Phage Therapeutics ..... Adaptive TCR ... Adarza BioSystems
.....
Addiction
Therapeutix
...
Addrenex Pharmaceuticals ... Adelor ... Adenosine
Therapeutics
... Adesto Technologies .... Adeza Technologies ... Adherex
Technologies ... Adhesys Medical .... Adial Pharmaceuticals .... Adicet
Bio .... AdiMab
... ADispell ... Adlyfe .... ADMA
Biologics .... Admittance
Technologies
.... Admune Therapeutics ..... Adnexus
Therapeutics ... Adrenergics .... Advanced
BioHealing ... ADS Biotechnology ... Aduro BioTech
.... Advanced Animal Diagnostics .... Advanced Biologics ..... Advanced
Bionics
... Advanced Cell Diagnostics ... Advanced Cell
Technology (now sub to Bio-Techne) ... Advanced Ceramics
.... Advanced
Circulatory .....
Advanced Countermeasures
Systems ... Advanced Diamond
Technologies .... Advanced Electron Beams ...
Advanced Fuel
Research ...Advanced Life Sciences ... Advanced Lighting
Technologies ... Advanced Liquid Logic
...
Advanced Magnetics ... Advanced Photonix ....
Advanced
Programming Concepts ... Advanced Receiver
Technologies .... Advanced Scientific Concepts ..... Advanced Targeting
Systems
.... Advanced
Technology
Materials.(ATMI) ... Advanced Uro-Solutions ..... AdvanDx ...
Advantic ..... Advaxis ..... Adventrx
... Adverum Biotechnologies ..... Advion BioSciences
...
Adynxx ...... Aegea
Medical ... Aegerion Pharmaceuticals .... Aeglea
BioTherapeutics
Holdings ..... Aerial BioPharma .... Aerie
Pharmaceuticals
... Aerin Medical ..... AerisPhotonics ...... Aerius
Photonics
... Aerodyne Research ... Aero Farms System
... Aerovel ..... AeroVironment ... Aerpio
Therapeutics .... AesRX
...
AETC ... Aethlon Medical
... Aethon .... Aevi Genomic Medicine .....
Affectiva
.... Afferent
Pharmaceuticals ..... Affigen .... Affinimark
Technologies
... Affinity BioReagents ... Affinium
Pharmaceuticals ..... Affinivax .... Affomix ....
Affymax ....Affymetrix ... aFraxis ... AgBiome ..... AgeneBio
....
Agennix ... Agenovir ..... Agenus .... Agere
Pharmaceuticals ..... Agile
Materials
... Agile
Planet ... AgileSwitch .... Agile Therapeutics ....
Agility
Robotics ..... Agilis Biotherapeutics .... Agiltron...Agilvax ....
Agilyx ....
Aagios
Pharmaceuticals... AgraQuest .... Agritope... Agrivida
... Agro Biosciences .... Aguila
Technologies.....Ahura Scientific.... Aiko Biotechnology
... Aileron Therapeutics .... Aimmune Therapeutics
(formerly
Allergen Research) ..... airtricity... Airware .... Airxpanders ....
Airway Therapeutics .... ait laboratories... Akadeum Life Sciences ....
Akamai
Physics
Akarna
Therapeutics
..... Akashi Therapeutics ..... Akcea Therapeutics ..... Akebia ....
Akero Therapeutics ... Akermin ..... Akers BioScience ..... Akita
Innovations
... Akouos ....
Akrevia Thera .... Akron
Polymer Systems ..... Akron Surface
Technologies ..... Akros Medical ....
Alabama
Cryogenics ... Alafair Biosciences .... Albany Molecular
(AMRI) ...A?
nanotech .... Alcon .... Alcresta
.... Aldagen
... Aldatu Biosciences ..... Aldea
Pharmaceuticals
... .
Alder biopharma Aldevon ..... Aldeyra Therapeutics (formerly
Aldexa Therapeutics) .... Alector .... Alexar Therapeutics .....
Alexion
... ....Alexza ....
Alfalight.... Algaeventure Systems ... Algenetix .... Algeternal
.... Algorithmia ..... Alien Technology
.... Alimera sciences.... Alios BioPharma ....Aliva
biopharmaceuticals ..... AliveGen .... Alivio Therapeutics .....
Alkermes...
Alkeus Pharmaceuticals ...
Allakos ... Allcast ....
Allegro Diagnostics ....
Allegro
microsystems ... Allena Pharmaceuticals .... Allergy Amulet
.....
Allerquest
.... Alleviant Medical .... Allied BioScience ..... Allied Minds ....
Alliqua .... Allos
Alloy Polymers .... Alloy
Surfaces .....
Allurion Technologies ... Allylix ... Ally Therapeutics ....
Alnara Pharmaceutical
...
Alnylam... Alper Biotech ... Alphabet Energy .... AlphaCore Pharma ...
Alphamed.... Alphatec
Holdings .....
Alphavax ... Alpine Biosciences .... Alpine Data
Labs .... Alpine Immune Sciences ..... Alseres ..... Algeternal
.... Alta Devices ... AltAir Fuels ... Altair
Therapeutics
... Altamira Technologies .... AltaRock
... AltheaDX .... Althea
Technologies ... Altimmune ..... Altor ...
Altra ...
Altura Medical ... Altus Pharmaceuticals ...
ALung
Technologies
... Alvine Pharmaceuticals ....
>Alycone
Lifesciences .... Alzeca ..... AMAG Pharmaceuticals
... Alzheon ..... Amaranth Medical .... Ambarella .....
Amberwave
... Ambiq
Micro ....
Ambit
Biosciences .... AMBP
Technology ... Ambri .... Ambrx ...
Ambry .... Ambys Medicines .... Amendia .... American Bionics .....
American
Gene Technologies International .... American Lithium Energy ....
American Medical Systems ....
American Science and Engineering
... America Stem Cell, now Targagyme .... American
Superconductor
... American XTAL .. Ames
Technology ... Amgen ... Amicus Therapeutics .... Amionx ..... Amnis
...
AMO
Pharma ..... Ampio Pharmaceuticals ..... Ampla
Pharmaceuticals ... Amplimmune .... Amplyx Pharmaceuticals
.....
Amprius .... ARMO
BioSciences
.... Amylin
Pharmaceuticals
... Amylyx ..... Amyris
Biotechnologies ... Anacor Pharmaceuticals ...
Anadys
Pharmaceuticals ... Anakim Biologics ....
Analog Computing
Solutions .... Analytical Space ..... AnaptysBio
... Anavex Life Sciences .... Anchor Therapeutics ...
Ancora Pharmaceuticals
... AnDAPT ..... Anexon .... Anew Optics ... Angeion ...
AngioDynamics
... Angiologix ... Angstrom Medica .... Angstron
Materials
... Animalgesic Labs .... ANI Pharmaceuticals ...
Animetrics .... Anivax .... Anivive Therapeutics ..... Annexon
Bioscience ..... ANP Technologies
..... Ansoft
... Ansun Biopharma (formerly NexBio) .... Antegrin
Therapeutics
..... Anthera
Pharmaceuticals .... Anthos Therapeutics .....
Antigenics ... Anue Systems ... Anulex Technologies
... Anybots ... AOBiome Therapeutics
(formerly
Nitrocell) .... AOptix Technologies
... Aortica ..... APA
Optics (Enterprises) ... Apellis Pharmaceuticals
.....
Apexigen ... Aperion
Biologics
.... Aphios
... Apic Bio .... Apieron ... Apnex Medical
... ApniCure .....
ApoCell ....
ApoGen Biotechnologies .... Apollo
Diamond
... Apollo Endosurgery ... Apollomics
(previously CBT
Pharmaceuticals) .... Apoplogic Pharmaceuticals
... Applied Biomolecular Technologies .... Applied Biosystems
.... Applied Defense Solutions ..... Applied Genetic Technology ...
Applied Nanotech ....
Applied
NanoWorks ... Applied Optimization ..... Applied
Optoelectronics ... Applied Physical Electronics ...
Applied Physical Sciences ... Applied Precision ..... Applied
Proteomics ..... Applied Quantum Technologies .... Applied Quantum
Technology
.... Applied Research Associates
... Applied
Science and Technology ... Applied Signal
Technology
... Applied Therapeutics ...... AppThwack ....
Aprecia Pharmaceuticals ....
Apricus
Biosciences
... APS BioGroup .... Apse .... Aptalis Pharma .... Aptevo
Therapeutics .....
Aptima ... AptamiR
Therapeutics .... Aptinyx .... Aptose
Biosciences .... Aptus
Endosystems ... Aquaback Technologies ...
Aqua Bounty
... Aquacue .... AquaHarmonics ..... Aqua Metals .... AquaMost
...
Aquarius
Technologies ... Aquestive Therapeutics ....
AqueSys
... Aqueti .... Aquion .... Aradigm ....
AragonPharmaceuticals
...
Aratana
Therapeutics ..... Arbor Biosciences< ..... Arbor Biotechnologie
..... Arbor Pharmaceuticals
...
Arbovax
... Arbutus BioPharma (formerly OnCore) ..... Arca Biopharma ....
Arcadia Biosciences ..... Arcadia Pharma ..... Arcantatura...
Archemix
... ArcherDX ......Arch Innotek ..... Arch Oncology ..... Arch
Therapeutics
... Arctic Sand Technologies .... Arcturus Therapeutics ....
Arcus Biosciences ..... Ardea Biosciences ...
Ardelyx .... Ardian .... Arena Pharmaceuticals
... Argentum ..... Arginetix
... Argo AI ..... ArgonST ... Argos Therapeutics ... Aria CV
...
Ariad Pharmaceuticals .. Ariosa Diagnostics ..... Arista MD
....
Arista Networks .... ARIZ Precision
Medicine .... Arkis BioSciences ....... Arkansas Power Electronics
.....
Armadillo Aerospace
... Armetheon .... ARMO BioSciences .... Armonica
Technologies .... Armorworks
... Armune BioScience ..... Aro Biotherapeutics
.... Aronora ..... Arpeggi
.... ArQule ... Arrakis Therapeutics .....
Array ... Array Information Technology ..... Arresto
Biosciences .... Arrien Pharmaceuticals ... Arrivo
BioVentures ..... Arrowhead Pharmaceuticals ..... Arrowhead
Research .... Arsanis ... Arsenal Medical
.... Arstasis ... Artel .... Arteriocyte
... Arterys
..... ArthroCare
...
Arthrosurface ... Artisan Pharma ... Artizan .... Artrility
Medical ..... ArunA Bio .... Arvegenix ..... Arvinas .... Arxan
Technologies .... Aryx
Therapeutics ..... Aryx
... Arzeda
... Asana Medical (now Regentsys) .... Asante Solutions .....
Ascelegen
Therapeutics .... Ascension
Orthopedics ... Ascent
Solar Technologies ....
Ascent
Therapeutics .... AsclepiX Therapeutics .... Aseptia .... Ash
Access Technology ....
AstroWatt .... Aspen Aerogels .... AspenBio
Pharma .... Aspen Products Group ....
Aspen
Technology
... Aspyrian Therapeutics .... Assurex Health ..... Astex
Therapeutics ...
Asthmapolis
.... Astralux
... Astrobotic Technology ....
Astronautics Corp. of
America ... AstroPower... AstroTerra ..
Astrum Solar ... Astute
Medical ....
Astute Medicales ... Asuragen
... Atacama ..... Atara Biotherapeutics ..... Ataxion ....
Athenex
(formerly
Kinex) ..... Athenix
... Athens Research ..... AtheroGenics ... AtheroMed ....
Athersys .... ATI Industrial
Automation
... Atlantia ... Atmocean .....
Atmospheric Glow
Technologies ...
Atomate ... Atomic Medical Innovations .....
Atomometrics
... Atomwise ..... Atoptix .... Atossa
Genetics
... Atreaon ....
Atreca .... Atreon Orthopedics
..... AtriCure ... Atrium
Medical ... ATRP Solutions ... aTyr Pharma .....
Audentes
Therapeutics ..... Audience
... Augmenix
.... AUM
Cardiovascular ... Aura Biosciences ....
Auris Health .... Auris Medical .... Auris Surgical Robotics
..... Aurora
Algae ... Aurora Flight
Sciences ....
Aurora
Imaging Technology ...
Aurora Spectral Technologies
... Auspex
Pharmaceuticals ... Ausra ... Auterra
.... AuthenTec .... Autolus Therapeutics .... Automated Dynamics ...
Automated
Medical Instruments .... Autonet ... Aushon
Biosystems ... AutoGenomics .... Autonomic Materials
.... Autonomic Technologies ..... Autonomous Technologies
....
Auxilium
Pharmaceuticals ... Avalanche
Biotechnologies ....
Avanir Pharmaceuticals
... Avant Immunotherapeutics ... Avanti Metal ...
Avaxia
Biologics ... Avedro ... Avelas Biosciences ....
Aveo
Pharmaceuticals
... Avery Therapeutics ..... AveXis .... Aviation Resources
Delaware .... AVI
BioPharma ... Avici Systems ... AvidBiotics
.....Avidity
Biosciences .... Avid
Radiopharmaceuticals
... Avila Therapeutics ... Avinger ....
... Aviragen Therapeutics (formerly Biota
Pharmaceuticals)
..... Aviron ..... Avisa Pharma .... Avita Medical Americas .....
Avitude .... Avrobio
..... AVT Simulation .... Aware ... Axcella Health (was Pronutria)
.....
Axelo .... Axerion Therapeutics
... Axial
Biotech .... Axial Biotherapeutics ..... Axion BioSystems
.....
Axion Power
... Axis Clinicals .... Axis
Semiconductor
... Axium Nanofibers ...... Axium Pharmaceuticals .... Axogen
.... Axonia Medical ....Axonics Modulation Technologies
Axsome Therapeutics ..... Axsun Technologies ... Ayasdi
..... Azaya
Therapeutics ... Azelon Pharmaceutical ... Azimuth
.... Aziyo Biologics ..... Azure Biotech ..... AzurRx BioPharma
Baby Genes .... Bacterial Robotics .... BacterioScan ....
Baebies
..... Bagaveev
.... Ballard
Power ... Bamboo Therapeutics ..... Bandgap ... Banner Life
Sciences ..... Banyan Biomarkers ... Bardy
Diagnostics .... BarioSurg ..... Baryonyx .... Barrier
Therapeutics ... Baseload Renewables .... Basis
Science
.... Bastion
Technologies
.... Batu Biologics ..... Bauhaus Software ..... Baxano ...
Baxano Surgical .... BayoTech ..... Beacon Biomedical ..... Beacon
Power ... Beam Therapeutics ..... Beat
Biotherapeutics .... Beeco
... Behavioral Recognition Systems .... Bellicum
Pharmaceuticals .... Belmont Instrument ....
Benchmark
Automation ... BeneChill
... Benefuel ... BeneVir Biopharm ....
Bennett
Aerospace .... Benson Hill
Biosystems ..... Benvenue
Medical .... Berg .... BerrieHill
Research
... BESS Technologies .... BetaBatt
...
BetaLED ....
LEDBG Medicine
... Bettergy .... Bexion Pharmaceuticals .... Bina
Technologies .... Bind
Bioscience ... Bind Therapeutics .... BinOptics ..... BiO2
Medical
... BiO2
Technologies
...
BioAmber ... BioAdvanTek ... BioAffinity
Technologies .....
Bioanalytical Systems
... BioBehavioral Diagnostics ... BioBridge
Global
..... BioCardia .....
BioCentra Molecular Innovations ..... Biocept
...
BioChemics ..... BioClin Therapeutics .... Bicycle Therapeutics .....
Bien-Etre
Labs ..... BioCold Genesys .... Bioconnect Systems .... BioConsortia
..... BioCritica
... BioCryst Pharmaceuticals ...
BioDelivery Sciences ... Biodesix .... BioDirection ..... BioDtech ...
BioFactura ... ..... BioE ...
BioFire .... BioFluidica ..... Biogenic
Reagents
.... BioGreenChoice ... BioHaven Pharmaceuticals ..... Bioheart
...
Biohelix ... Bio-Imaging Technologies
...
Bioincept .... BioKier ..... Biolex Therapeutics
... BioLife4D ..... BioLink Life
Sciences
... Biolinq (formerly Electrozyme) ,,,, Biologics
...
BioMagnetic Solutions ....
BioMarin
Pharmaceutical
... BioMarck
Pharmaceuticals .... bioMASON ..... Biomatrica ...
BioMedical
Enterprises
... Biomedical Sciences ..... Biomedical
Structures ...
BioMedix .... Biomeme .... Biometric
Signature
... BioMimetic Therapeutics
... BioMotiv .... BioNano
Genomics ... BioNanomatrix ... Bionostics
Holdings
... Bio-Path Holdings ..... Biophan Technologies
... Biophysical ... BioProcessors ...
Bioptigen
... Bioptix .... BiOptix Diagnostics ..... BioPulping
International
...
Biopure ... Biorasis ..... BioRelix ... BioResource
International
...
BioRestorative Therapies (formerly Stem Cell Assurance) ....
BioSante Pharmaceuticals ... BioScale
.... BioSense
Technologies ... BioSensics .... BioSentinel
Pharmaceuticals
... BioSig Technologies ..... Biosortia Pharmaceuticals ....
BioSphere Medical
.... Biostage (formerly Harvard Apparatus
Regenerative
Technology) ..... BioStructures .... Biosurfaces .... Biosym
Technologies later Accelrys
....
BioSystem
...
Biota Pharmaceuticals .... Bio-Techne ..... BioTechnique ....
BioTechPlex .....
Biotectix
....
Biotel
.... BioTelemetry (formerly CardioNet) ..... BioTex
....
Biothera
... BioTheranostics ... Bio Time ...
Biotix
... Biotronic NeuroNetwork ..... Biotronik ....
BioTrove
... BioVaxys .... Bioventus ..... Biovest International ....
BioVex
... BioVirtua ..... Bird Rock Bio (formerly RuiYi) .....
Birich
Technologies .... Biscayne Neurotherapeutics ..... Bitstream
... Black
Diamond Therapeutics .... Black-I Robotics
... Black Sand ... BlackThorn
..... BladeLogic
... Blasch Precision Ceramics .... Blaze
Bioscience ... Blend
Therapeutics ....
BL Healthcare ... Block Engineering ...
Bloom Energy
... Bloo Solar ..... BluDiagnostics ..... Blue Belt
Technologies
...
Bluebird
bio ...
BluDiagnostics .... Bluefin Robotics ... Bluegrass
Proteins
.... Bluegrass
Vascular
Technologies .... Blueprint
Medicines ...
BlueRock Therapeutics ..... Blue
Sky Batteries ... Bluewater Bio International ... Blue Water
Vaccines .... Bolder Surgical ... Bolt
Biotherapeutics .... Bolt Threads ....
Boom Supersonic ..... Boragen .... Boston Biochem
... Boston Biomedical ... Boston Dynamics
...
Boston Engineering ... Boston Micromachines ... Boston
Micromachines (formally Boston
Electrometallurgical .... Boston-Power
...
Boston
Therapeutics ... Bot Dolly .... Boundless ... BoXZY
..... Braeburn Pharmaceuticals ..... BrainCells
... BrainScope .... Brain Sentry ....
Brain Tunnelgenix
Technologies .... BrainXell ..... Branch Medical Group ..... Brayton
Energy
.... Breathe
Technologies ... Breethe .... Breonics ...
BreviTest
Technologies
..... Brewer
Science ... Bridger Photonics .... Bridgelux
... Brightsource Energy ... Bright View
...
Brimrose Corp of America ... Briteseed .... Brock Rogers Surgical
...
Bromium
.... Brooks
Automation ...
Bruker Daltonics .... Buffalo BioLabs ..... Burl
Concepts
..... Burr Oak
C12 Energy ... C2Sense .... C3Nano
... C4 Therapeutics .... C8
Sciences ....
C9 ... Cabaletta Bio .... CABG Medical ....
Cadence Pharma ....
CadheRx
Therapeutics
.....
Caisson Biotech .... Calabazas
Creek
Research .... Caladrius
Bioscience ... Cala Health ..... Calando
Pharmaceuticals
... Calbiotech .... Calera ... Caliber Biotherapeutics ....
Calibra
Medical ... Calient ... California Wave Power
Technologies ..... Calimmune ..... Caliper Life Sciences
....
CaliSolar ... Calistoga Pharmaceuticals ...
Calithera
BioSciences .... Calixa
Therapeutics ... Callidus Biopharma ... Calporta
Therapeutics
.... Calspan .... Caltech Metals ... Calysta .... Calyxt .....
Cambridge
Endoscopic Devices ... Cambridge Heart
.... Cambridge
Research & Instrumentation ... Cambrios
Technologies .... CAMX ..... Candela Laser ....
Cancer
Genetics .... Cancer Prevention
Pharmaceuticals .... CanDiag .... Canopy Biosciences ..... Capesym
... Capillary
Biomedical ..... Capio Biosciences .... Capnia
... CAPP Medical ..... Capricor Therapeutics .... Cara
Therapeutics .... Carbon .....
Carbon
Design
Systems ... Carbtex Technology
.... Carbylan Therapeutics ..... Cardeas
Pharma ....
CardiacAssist ..... Cardiac Concepts ...
Cardiac
Dimensions
... Cardiac Science ..... Cardialen ..... CardiAQ Valve
Technologies ... Cardica
... CardioDx
... Cardio Flow ..... CardioFocus ... CardioInsight
Technologies .....
Cardiokinetix ..... CardioMag ... CardioMEMS .... Cardionomic ....
CardioNXT ..... Cardiorobotics
...
Cardiosolutions ... Cardiosolv .... CardioSpectra ... CardioTech
... Cardiovate ..... CardiOx ...
Cardioxyl
Pharmaceuticals
.... CareDx (formerly XDx) .... Caribou Biosciences
.....
Carigent Therapeutics .... Carisma Thera (formerly CARMA Therapeutics)
..... Carlsme .... Carmot Therapeutics
..... Carnegie Robotics
.... Carnegie Spee .... ... .... Carnot BioSciences ....
CaroGen .... Carter Aviation Technologies .... Carticept
Medical ... Cartiva ..... Cascade Designs ...
Cascade
Microtech
... Cascadian Therapeutics (formerly Oncothyreon) ..... Casma
Therapeutics .... Castle Pharmaceuticals .... Castle Creek
Pharmaceuticals
Catabasis Pharmaceuticals ... Catadon
Systems ... Catalyst Biosciences ... Catalyst Pharma
.... Catalytic Innovations ..... Catalyze ..... Catelectric
.... Cebix .... Cedarburg Pharmaceuticals .... Cedilla
Therapeutics ..... CeeTox
... Celadon ... Celator Pharmaceuticals
... CelcuityCeldara Medical ..... Celladon .... Cellara .... Cell Care
Therapeutics ..... Cellceutix
.... CellCyte
Genetics ... Cell Design Labs ..... Celldex Therapeutics
... ..... Cellectar ... Cellerant
Therapeutics
... Celleration .... Cell Genesys ... CellRight
Technologies
..... Cellular
Bioengineering
...
... Cellular Bioengineering ..... Cellular Biomedicine Group
.....
Cellular Dynamics International .... Cell>Point
.... CellSavers ..... Cellscape .... Cellscript
..... Cell
Signaling Technology ...Cell
Therapeutics (now CTI
BioPharma)
... CellTraffix ... CeloNova Biosciences
..... Cel-Sci
.... Celsion ...
Celtaxsys ..... Celula..... Celularity ..... CellzDirect ...
Cempra Pharmaceuticals.
.... CeNeRx
BioPharma ... Centocor .... Centrexion Therapeutics .....
Centrose ... Centice .. Century Therapeutics .... Centritec
Seals ... Cephalon
... Cepheid
... Cephalon ... Ception Therapeutics
... Cequent
Pharmaceuticals ... Cerebras Systems ..... Ceradyne ...
Ceramitron
... Cerapedics
.... Ceramatec
... Cerevast Therapeutics .... Cerealus Holdings
... Cerecor .... Ceregene ...
Cerahelix
.. Ceres Nanosciences ..... Cerexa .... Cerion
Enterprises ...
Cermet ... Cernostics ..... Cerulean Pharma
... Cerus ... Cervel Neurotech .... Cesca
Therapeutics
....
Ceterix
Orthopaedics ... CFD Research ..
CFX Battery
.... CGI Pharmaceuticals ... ChaCha
... Chantilly BioPharma .... Chapman
Innovations ... Charles River Analytics .... Charles
River
Lab ... Charter Medical ..... Chase Therapeutics .... CHASM
.... Chatham
Therapeutics .....
Checkerspot ..... Chemat
... Chembio Diagnostic
Systems .... ChemImage ... Chemir Analytical
Services ...
ChemoCentryx
... Chemtura ....
Chesapeake Sciences
...Chesson Labs ... Chiasma .... Chimera
Bioengineering ..... Chimerix
... Chlorogen ... Choice Therapeutics
... Chondrogenics
... Chordia
Therapeutics .... Chorum Technologies
.... ChromaCode
..... ChromaDex
..... Chronix
Biomedical
... Chrysalis BioTherapeutics .... Cibus
Global
... Cidara Therapeutics .... Ciena
....Ciencia ...
Cilion .... CimaBay Thera ..... CinCor Pharma .... CinRx ....
Ciranova
... Circle
Technologies ..... Cirius Therapeutics ..... CivaTech
Oncology
.... CiVi Biopharma ..... Civitas Therapeutics
..... Claret Medical .... Clarassance ..... Claresta
Solutions
.... Clark-MXR ...Claros
Diagnostics
.... Clean Diesel
Technologies ... Clear Catheter Systems .... ClearCount
Medical
Solutions .... ClearEdge
Power .... Clear Guide Medical .... Clearside
Biomedical ... Cleave Biosciences ... Cleveland BioLabs ...
Cleveland
Polymer Technologies ..... CleverSet ... Clinical Data
... Cloudant ... CloudMade ... Cloud
Pharmaceuticals
(formerly Teradiscoveries) .... Clovis
Oncology ... Clovis Tech ..... CMC Biologics .... C-Motive Technologies
.... CoAdna,Holdings ..... CoAxia ....
Cobalt
Biofuels
...
Cocrystal Discovery ... Codexis
... Codiak BioSciences ..... Codon
Devices ... Co-D Therapeutics .... Cofactor
Genomics ....
Cogenra .... Cogentix Medical ..... Cognex
...Cognition
Therapeutics .... Cognitive Code
... Cohera
Medical .... Coherus Biosciences .... Cohesive
Technologies ... ColdQuanta .... ColdWatt ... Collagenex
Pharmaceuticals ...
Collegium Pharmaceutical ... CoLucid Pharmaceuticals
... Columbia Labs ..... CombiMatrix ...
CombinatoRx
..... Combined Energies .... Combinent
BioMedical Systems ... Comet Therapeutics .... Comfort Motion
Technologies
...
Commonwealth Biotechnologies ... Commonwealth
Fusion Systems ..... Compact Membrane Systems ...Compass
Therapeutics .... Compellent Technologies ... Compendia
Bioscience
.....
Complete
Genomics ....
Complexa
..... Conatus
Pharmaceuticals ... Concert
Pharmaceuticals
.... Concordia Fibers ...Concurrent Technologies ...
Conductus
.. Confluence Life Sciences ..... ConforMIS ...
Cognigen
.... Conispire
.... ConjuGon .. Connecticut
Valley Bindery ... Consonus Technologies
...
Constellation
Pharmaceuticals .... Context Therapeutics ..... Contour Energy
Systems ControlRadSystems ..... Convelo
Therapeutics ....
Conventus
Orthopaedics ..... Convergen
... ConverGene .... Convio .... Convoy
Therapeutics
.... Cool-Bio
.... CoolCAD Electronics .... CoolChip Technologies
....
Cool Earth
Solar
.... Cooligy ... CoolTech .... Corbus
Pharmaceuticals
..... Corcept
Therapeutics
...
Cordex Systems .... CoreStreet ... CoreTek ...
.Corgenix
Medical
... Corindus ....Corinthian
Ophthalmic ... Corium International .... Corixa
....
CorMatrix
Cardiovascular
.... Cornami ..... Cornerstone Research
... Cornerstone BioPharma then Cornerstone
Therapeutics
..... Cornerstone Therapeutics .... Coronado
Biosciences ... CorQuest Medical ..... Correx ... Corridor
Pharmaceuticals
... Cortana ..... Cortendo AB ..... Cortexyme ....
Corvidia
Therapeutics ..... Corvus
Pharmaceuticals
..... CosmosID ..... CoStim Pharmaceuticals
.... Cougar
Biotechnology ...
Coulbourn
Instruments .... Coulter Pharmaceuticals ... Cour
Pharmaceutical
Development .... Coverity ..... Creare ...
Creative
Hybrid Solutions .... Creatv MicroTech .... Cree
Research ... Crescendo Bioscience .... Crinetics
Pharmaceuticals
....
CrispTek .... Critical Therapeutics .... CritiTech
... Crossbar .... Cross Current ..... CrossFire
... Cruise Automation .... Crux Biomedical
...
CryoCor ...
CryoLife ... Cryomedical Sciences ..... Cryptonite .....
Crystal
IS
...
Crystal Systems ... Crystallume ... CSA
Engineering ... CS-Keys ... CTD Holdings
..... CTI
BioPharma (formerly
Cell Therapeutics) .... Cubist
Pharmaceuticals
... Cue Biopharma .... Cullinan Oncology ..... Cumberland Pharma ....
CuraGen ... Current Motor
...
Curtana Pharmaceuticals .... Custom Electronics .... CVD
Equipment ..... CVRx
... CV
Therapeutics ... Cyanotech ..... Cyberdyne .... CyberKey Solutions
... Cyberkinetics Neurotechnology ... Cybernet Systems
... CyberOptics ... Cydan .... Cykloburn
Technologies ..... CymaBay
Therapeutics
.... Cymbet ... CyMedica Orthopedics ..... Cymer
...
Cynosure ... Cyntellect ... Cypher Genomics ... CyPhy Works
... Cypress Bioscience ... Cyrus Biotechnology .....
Cyteir
Therapeutics ..... Cyterix
Pharmaceuticals ...
CytImmune .... CytoBioScience ..... Cytocentrics ..... CytoCore
(formerly Molecular
Diagnostics) ..... Cytocybernetics ..... CytoDyn
.... Cytogel Pharma
.... Cytokinetics
... Cytometix ....CytomX ...
Cytonome
....
Cytori Therapeutics ... Cytophil CytoSolv
... Cytosorbents ..... Cytovas ... CytRx ..... Cytyc
...
CyVek
Dabble ..... Dairyvative Technologies ..... Daktari Diagnostics ... Dance Biopharm .... Dara BioSciences ... Daré Bioscience Operations .... Dart Therapeutics ... DaStrong .... Datafiniti .... Data Physics ... DataRobot ..... Dato (formerly GraphLab) .... Datuit .... daydream.io ..... Daylight Solutions .... DayStar ... DayZero Diagnostics ..... DBS Energy ... DCL Medical Laboratories ... Deca-Medics ... deciBel Research .... Decibel Therapeutics ..... DecImmune Therapeutics ... Deciphera Pharmaceuticals ..... Decision Biomarkers ... Deepwater Wind .. Defense Engineering .... Defense Research Associates .... Defibtech ... Dekkun .... Delcath ... Delinia ..... Deltanoid Pharmaceuticals ... Denali Medical ... Denali Therapeutics ..... Dendreon ... DeNovo Sciences .... DeNovis ... Deposition Sciences .... DermAvance Pharmaceuticals ... DermBiont .... Dermira ... Desalitech .... Descartes Labs ..... Design Knowledge ..... DesignMedix ..... Detcon ..... DE Technologies ... Devicix ..... Dew & Ken Group ... Dewey Electronics ... Dewpoint Therapeutics .... Dexcom ... Dharmacon ..... Diagnostic Biochips .... Diagnostic Hybrids ... DiaMedica ..... Diamond Foundry ..... Dianomi Therapeutics .... Diatomix ..... Dicerna Pharmaceuticals ... Diffusion Pharma ..... DiFusion Technologies ... Digene ..... Digirad ... DigiSight Technologies ..... Digital Fusion ... Digital Lumens ... Digital Optics ... Dignify Therapeutics .... Dimien .... Dimension Therapeutics .... DioGenix .... Dipexium Pharmaceuticals ..... Directed Manufacturing .... Directed Perception .. Disarm Therapeutics .... Disc Dynamics ... Discovery Genomics ..... Discovery Labs .... Displaytech ... Distributed Energy Systems ... Divergence ... Diversified Energy ... D. Light ... DMC Biotechnologies ... DNAnexus ..... DNAPrint Genomics ... DNAtrix .... DNV GL .... Dova Pharma ..... DoX Systems ... Dracen Pharma ..... Dragon Systems .. Dragoon ITCN ..... Drilling Info ... DrillMap .... DropWise .... DR Technologies ..... DrugCendR .... DSM .... DT Solar ... DuBay Ingredients ... Dune Medical Devices ..... duPont Aerospace ... Dura Biotech .... Durata Therapeutics ... Durin Technologies .... DVS Sciences .... DxUpClose .... Dyadic International ..... Dyax ...DynaBil Industries ... Dynasil ... Dynavax Technologies ... Dyne Thrapeutics ... Dynetics .... Dynogen Pharmaceuticals
E3 Clean .... Eagle
Optoelectronics ... Earl Energy .... EarLens .... Earth Networks ....
Earthrise
Nutritionals ... eASIC ..... Eboo Pharmaceuticals .... EBR
Systems ..... Ebullient
....
Echelon .... Echodyne
..... Echometrix ... EchoPixel ..... Echo Therapeutics (was
Sontra)... ECI Biotech
... ECM Technologies ..... Ecocurrent
... EcoPesticides .... EcoPro Polymers .....
Eccrine Systems ..... Ecovative
Design ... Edaptive
Computing .... Eden
Bioscience
... Edenspace
Systems ... Edge Therapeutics ..... Edico Genome .... Edison
Agrosciences ..... Editas
Medicine .... EEStor
... Effector
Therapeutics .... Egalet .... eGenesis .... Eiger BioPharmaceuticals
..... Eikos ... E-Ink
... EIS .... Ekos ... EKR Therapeutics .... Ekso
...
Elcelyx Therapeutics ... Electrical
Geodesics .....
ElectroCell
Technologies
... ElectroChemical Systems ... Electro Energy
...Electromed ... Electro Optical Sciences ...
Electro
Scientific ... Electrozyme ....
Elementary Robotics ....
Elemetric Instruments
... ElevateBio .... Elevation Pharmaceuticals
... Eleven
Biotherapeutics ... Elira Therapeutics
..... Elixir Biopharm ... Elixirgen Therapeutics ..... Elixir
Pharmaceuticals ...
Ellipse Technologies ..... Elon ...
Elstar Therapeutics ..... eMagin .. Embera
NeuroTherapeutics .... Embodied ....
EmboMedics
.....
Embrex ..
EMCORE
...
Emerald BioStructures
.... Emergent BioSolutions ...
Emergent
Technologies ... EM Photonics .... Empire Genomics
.... Empire
Robotics ....
EMRes Technologies
... Emtora Biosciences (formerly Rapamycin Holdings) .... Emulate ....
Enable
Injections ...... Enanta Pharmaceuticals ..... EnChroma ..... Encite
...
Encoded Genomics .... Encoded Therapeutics .... Encompass Bioscience
..... Encore
Vision .... Encysive
Pharmaceuticals ... Endeavor Robotics ..... Endece
...
Endgame Technologies
... EndoChoice .... Endocyte ... EndoGastric
Solutions
... Endo International ..... Endoscopic
Technologies ... Endosee ..... EndoStim
.... Endotherapeutics ..... Ener1
... EnerG2 ... Energen
... Energesis Pharmaceuticals .... Energetiq
Technology ... Energid Technologies ... Energous
..... Ener-G-Rotors
... Energy Control ... Energy Conversion
Devices .
.. Energy Focus ..... Energy Recovery ... Energy
Solutions
... Energy Storage Systems ..... EnerMat Technologies .....
EnerMed ..... Enertech
Environmental ... EnerVault ... Engineered
BioPharmaceuticals
.... Engineered Propulsion ...Engineous
Software
... Enlibrium ..... Enlight
Bioscience ... EnSync Energy Systems (formerly ZBB Energy)
.....
Ensysce Biosciences ... Entasis
Therapeutics ..... Entech
... Entegrion ... Entellus Medical .....
Entera
Biotech .... Entergem Ventures .... EnteroMedics
... Entia Biosciences ..... Entira Bio .... Entopica
Therapeutics
...
EntreMed
... Entrada Therapeutics ..... Entra Pharmaceuticals
... ENTrigue Surgical ...
Envia
Systems .. Entrotech Life Sciences ..... Entvantage
Diagnostics
..... EnviroFlight ..... Envisia Therapeutics
..... Envistacom .... EnVivo
Pharma ... Enzenia ... Enzium
... Enzo Biochem ... Enzymatics ... EnzyMed ..... Enzyvant
.....
EO2
Concepts
.... EOIR
... Eonix ....
EpiBiome ....
EpiBone .... Epicentre
Biotechnologies .... Epic Sciences .... Epic Systems ..... Epicypher
.... EpiEP ...
Epion
... Epiphany Solar Water Systems .... Epitomics
...
Epiva Biosciences ..... EpiVax ... EpiWorks .... Epix
Pharmaceuticals ... Epizyme
...
Eppin Pharma .... EqualLogic ... Equex
... Equillium .... Equipment
Concepts ...
EraGen Biosciences ... Erallo Technologies
... Erasca .... Ercole
Biotech ... ERT ..... Escalier Biosciences BV ..... Escalon
Medical
.... E-Scape
Bio ..... Escient Pharmaceuticals ..... Escoublac
....
eScription
... eSolar ... Eso-Technologies
... Esperance Pharmaceuticals ..... Esperion
Therapeutics
..... Essential Biotechnology
..... Essential Medical .... Essentient ....
Essex... Eta Devices ..... Eta-Gen .... Etegent
Technologies
... E-Tek
Dynamics ... Eton Pharma ..... Euclid
Labs .... Euclises Pharmaceuticals ..... Eureka
Therapeutics ..... Euthymics
Bioscience ... EVapt .... Evelo
Therapeutics ....
Evena Medical ..... Ever Cat Fuels
...
Evergen Biotechnologies ... Evergreen Solar ... Everspin
Technologies .... Evestra ....
Evident
Technologies ... Evofem Biosciences ....
Evoke Pharma .....
Evolution
Robotics ... Evolv .... Evolve BioSystems ....Evolved By Nature .....
EWI .... Exact
Sciences .... Exagen
Diagnostics ... Excelimmune ... Excel
Technology .... Excision BioTherapeutics ..... Exelixis .....
Exelixis
Plant Sciences ... Exemplar Genetics .... Exo .....
Exogenesis
..... Exone .... Exonics Therapeutics .... Exosome
Diagnostics ..... Exovita .... Biosciences .... ExploraMed
NC4 ...
Expression
Analysis .... Exquadrum .... Exsulin
....Extreme Molding ... Extremity Innovations ... EyeGate
Pharmaceuticals ... EyeNetra .... EyeTel
Fallbrook
Technologies
... Famigo ... Faraday Pharmaceuticals .... Farodox
Energy
Storage
...
FarSounder ... Far-Tech.... FastCAP Systems ...
Fate
Therapeutics
... Fathom .... Fe3 Medical .... FEI ... Femasys
.... Femta
Pharmaceuticals
.... Ferrate
Treatment Technologies ... Ferric Contrast ...... FerroKin
BioSciences ....
Fervo Energy .... Feuz Manufacturing ... FGC Plasma Solutions
..... Fiber and Sensor ....
Fiberight ...
Fiber Materials ... Fibersense ... Fiberstar ....
Bio-Ingredient
Technologies ... Fibertek .... Fibrocell Science
... FibroGen ... Filter
Sensing Technologies ...
Finally Light
Bulb ..... Finch Therapeutics Group ..... FineLine Prototyping ....
Finisar
... Fire Alarm
Specialty Design .....
Firefly
BioWorks ... Firefly Energy .... Firefly LED
...
First Solar ... Fisker Automotive ... Five Prime
Therapeutics .... Flex Biomedical
... Flexion Therapeutics ... Flex Pharma
.... Flextronics
America ....
Flexus Biosciences .... FLIR Systems
.. FloDesign
Wind Turbine ... FlowCardia
...
FlowMedica .... FlowMetric .... Flow Metrix
...
FluGen
... Fluidic Energy ... Fluidigm ... Fluid Innovation
Group
... Fluidnet ... Fluidnet
FluoroPharma
... Fog Pharma ..... Foghorn
Therapeutics .... FokusLabs .... FoldRx Pharmaceuticals
...
Follica ...
Footnote .... Foresight Biotherapeutics .... Forest Devices .... Forge
Therapeutics .....
F-Origin
... Forma
Therapeutics ...
Formlabs
.... For-Robin ..... ForSight Vision5 .... Fortis Therapeutics .....
Forty Seven ..... Forum Pharmaceuticals ..... Forus
Health ... Foster-Miller .... Foundation Medicine
... Fox Chase Chemical Diversity Center ....
Fractal
Antenna Systems ... Fractyl Labs ..... Freedom Meditech
... Free
Flow Power ... Free Form Fibers .... Freenome ..... Froedtert
Health ..... Frontier
NanoSystems ..... Frontier Technology ..... Front Range Biosciences
.... FTL Solar
...
FuelCell Energy
... Fuel Tech
.. Fulcrum Therapeutics ..... Fulgent Therapeutics ..... Full
Spectrum Genetics .... Furiex
.... Fused
Innocation.
...
Fusion
Coolant Systems ... Future Technologies
G1 Therapeutics ..... G3 .... Gadusol Laboratories (aka
Seaceuticals) ..... Galderma .... Galectin Thera ..... Galenea ...
Galena
Biopharma
.... Galera
Therapeutics ..... Galil Medical ..... Galleon
Pharmaceuticals ... GAM Enterprises .... GameSalad
... Gamma Medica Ideas ... Garland
Technology .....
Garwood Medical Devices ..... GATR Technologies ..... G-Con .... Gecko
Biomedical .... Gecko Robotics .... Gel Combs .... Gelesis ...
Geltech ...
Gema Diagnostics .... GEMFIRE .. Gemin X Pharmaceuticals
... Gemmus
Pharma ... Gemneo Bioscience ..... Gemphire Therapeutics
......
Gemstone
Biotherapeutics
..... Gen9 ...
Genaera ...
Genalyte
... Genapsys .... GenAudio .... Gene by Gene .... GeneCentric
Diagnostics
... Genelabs Technologies ... Gene
Logic ... Geneoscopy ..... General Compression
...
General
Pneumatics
..... Generation Bio ..... Generex
Biotechnology ... Gene Security Network .... GeneSegues
Therapeutics ..... GenesisLabs ....
GeneSystems ... Genetesis .... Genetic Networks ..... Genetix
Pharmaceuticals
... GeneTx Biotherapeutics ..... Geneu .... Genia
Technologies
.... GenMark Diagnostics
.... Genoa Pharmaceuticals ..... Genocea
Biosciences
... Genomatica
... Genome Profiling ... GenomeQuest ... Genomic Health
...
Genomind ....
Genoptix
Medical
Laboratory ... Genor ... Genprex .... Gen-Probe
...
GenSpera
.... GenTel BioSciences ... Gentris ... GenturaDx
...nbsp; GenVec ... GenWay Biotech ..... Genzyme .... Geocent
.... Geocove ..... Geomagic
... GeoMed
Analytical ... GeoVax Labs ...
Geospiza
... Germfalcon ..... Geron ...
Gevo
..... GI Dynamics
...
GigOptix
... Gilead Sciences .... Giner . ..
Ginkgo BioWorks
.... Glauconix ..... Glaukos
.... GlideLine
Systems ... Gliknik ... Global Blood
Therapeutics
...... Global Cancer Diagnostics ..... Global Positions ...
Global Blood Therapeutics ....
GlobeImmune ....
Gloucester Pharmaceuticals ... Glowforge ..... GlucaGo ...
GlycoFi
... GlycoMimetics .... GlyGenix ... Glympse Bio
.... Glyscend .....
GlySens
... GMZ
Energy
... GnuBio
.... Goddard Labs .... Goldfinch Bio ..... Good Start Genetics
.... Gore
Photonics ... Gossamer Bio ..... Gotham Biotech .... Gotham
Therapeutics ..... GPC-Rx
... gRadiant Research ... Gradiant ....
GraftWorx
..... Grail ..... Graphene
Energy
... Graphenix Development .... Graphic
Surgery ... GraphLab (now Dato) .... Grassroots Biotechnology
...
Greatbatch
... GrayBug ..... Graybug Vision ..... Great Basin Scientific .....
GreatGrow Maryland ....Great North Lab .... GreatPoint Energy
... Green & Grow .... GreenFuel
Technologies .... Greenlight Biosciences .... GreenMark Biomedical
..... Green Mountain Radio
Research .... GreenSight Agronomics ..... Green Sulfcrete
.....
GreenTech America
... Greenwich Geriatrics .... GridBridge .... Grid
Therapeutics
..... Gritstone
Oncology
..... GRO Biosciences ..... Group14 Technologies ..... Grove
Instruments
... Grow Home Organics
.... GSI Technology ... GT Advanced
Technologies ...
GTC Biotherapeutics ... G-Tech Medical .... GT
Equipment .... GTI
Diagnostics
... GT Medical
Technologies ..... GTx .... Guardant Health .... Guided Surgery
Solutions
....
Guided
Therapeutics
.... .... Guided Therapy Systems ..... Gynesonics .....
G-Zero
Therapeutics
2 Energy Now ...... H2O Score ..... H2Pump ...
H2Sonics
.... H3
Biomedicine ... HNC Software ... Halozyme ...
Hana
Biosciences .... Hansen Energy and Environmental
....
Hansen Medical ... Haplogen Genomics ..... Harbor
Technologies .. Hardcore Computer ... HarkerBio .... Harmony
Enterprises ....
Harpoon Medical .... Harpoon Therapeutics .... Harvard Apparatus
Regenerative Technology .... Harrisvaccines .... Harvard Bioscience
... Harvest Automation .... Harvest Power ...
Harvest Technologies .... Healionics .. Health Diagnostics
Laboratories .... HealthMyne ....
Healthtronics
.... Hearforward
... Heartland Robotics .... HeartWare International
... Heat
Biologics .... ... HeatGenie ... Helicos
BioSciences
... Helion Energy .... Heliovolt ...
Helius Medical
Technologies ..... Helix
Therapeutics
... Helomics (formerly Precision Therapeutics)
.....
Hemadvance ..... HemaQuest Pharmaceuticals ... Hemarrest ... Hemera
Biosciences .... Hemispherx Biopharma .... HemoGenyx .... Hemoshear
Therapeutics ..... HemoSonics..... Hemostasis
... Hennepin Life Sciences .... Hepregen ... Heraeus Medical
Components .... Herley Industries
... Hermes Biosciences ... HexaTech
.... Hexfuel .... Hibernaid .... Highbury Defense
Group .... High Impact
Environmental
.... High Performance
Technologies ... High Point Pharmaceuticals .....
Histogen
.... HighRes Biosolutions .... Histogenics
... HistoRx
... HistoSonics .... HJM
Precision .....
HocusLocus ..... Hoku
Scientific
... Holaira .... Hollingsworth & Vose .... Hollis-Eden
Pharmaceuticals ... Holomni .... Homology Medicine
.....
Honeycomb Batteries .... Hontek
... Hookipa Pharma .... Hoopers Island
Oyster Aquaculture ...
Hoppe Tool
.... Hoth Therapeutics ..... Howe Industries .... Hsiri
Therapeutics ..... HTG
Molecular ..... HTSS
...
Humacyte
...
Humanetics ..... Human
Genome
Sciences ...
Human
Metabolome Technologies .... HuTerra .... Huya Bioscience International
.... Hybritech ..... Hybrivet .... HYCOR
Biomedical ...
Hydra Biosciences ...
HydroCision ... Hydrogen
Safety ... HydroLogic Industries .... Hygeia
Therapeutics
... HyperBranch Medical
Technologies ... Hyperion Therapeutics ... HyperMed
... HYPRES .. Hy-SyEnce
... HyTrust
IAP ... IBC Advanced .... iBiquity Digital ..... Ibis
....
Iblogix
.... IBT
Laboratories
... Icagen .... Icardiac.... Ichor Medical Systems .... Iconic
Therapeutics ..... Icos.... ICX....
Idaho.... Ideal
Converters ... Ideapaint.... Ideaya Biosciences ..... Idera
Pharmaceuticals ..... ID Genomics ....
Idevices
... IDx ..... iFirst Medical Technologies ...... IFM
Therapeutics
..... Igenica
Biotherapeutics .... IGM Biosciences ..... Ignyta.... Ii-IV
.... Ikaria... Ikonisys... Illinois Superconductor.... Illumigen....
Illumina.... Illuminating Diagnostics ..... Illuminoss....
Illumitex.... Imagen Energy .... Imagevision.... Imaging
Biometrics... Imagineoptix ... Imago Instruments... Imanis
Life...
Imbed Biosciences... Imetalx... Immco... Immersion... Immtech...
Immucell .... Immucor ....
Immune... ... Immune... Immune Pharma .... Immunetics...
Immunex...
Immunexcite...
Immuneworks... Immunexpress ..... Immunic ..... Immunicon...
ImmunoCellular Thera
.... ImmunoChemistry
Technologies ..... Immunocore...
Immunogen... Immunome ..... Immunomedics..... Immunomic Therapeutics
.....
Immunophotonics ... Immurx... .... Immusant...
Immusoft ..... Impact Biomedicines .... Impact Proteomics
.... Impact Science...
Impel
Neuropharma... Imperium Renewables... Impinj... Implant
Sciences... Impossible Foods .... Imprimis Pharmaceuticals .... Imprint
Energy .... Impulse
Monitoring ... Imricor Medical Systems ..... Imris .....
Imthera...
I-nalysis ... Inari Agriculture .... InCarda Therapeutics ....
INCELL .... Incelldx
..... Incitor (now XF
Technologies) .... Incodema3D ..... Incontrol
Research... InCube Labs ..... Incyte ....Incytu... Indalo
Therapeutics ..... Indiana
Nanotech... Indi Molecular ... Industrial Heat ..... Industrial
Perception...
Inentec ... InfaCare Pharmaceutical .... Infarct Reduction
Technologies .... Infinera...
... Infinia... Infinite Electronics .... Infinity... Infinium
.... Inform
Genomics... Infoscitex... Inframat... Infraredx... Infrascan... Inf
Robotics ... Infusion Medical ... Ingeneus... Ingeneron .....
Inhibitex... Inhibkase
Therapeutics .... Inhibrx< .... INI
Power... Inland Labs ..... Inmobly .... InnAVasc Medical ....
Inneroptic...
Innerpulse... Innocrin Pharmaceuticals ..... Innography...
... Innopad... Innotec ..... Innovalight...
Innovari Energy Design Microplate Scientific...
pulmonary solutions.... silicon... Innovate Biopharmaceuticals .....
Innovative Spinal...
Innovative... Innoventiontech ... Innovention (now
Ccardiorobotics) ... Innovative Trauma or...
Innovolt ...
Innowave... ... ... Innoviva ...
Innov-x... Inocucor ..... Inorganic Specialists... Inotek...
Ino
.... Inova
Labs
Biomedical... Inovio... Inovise Medical ..... Inozyme Pharmaceuticals
..... Inphase...
... Inphi... Inpria ..... Inscripta ..... Insert MRI...
Insight...
..Insite Vision...... Insitu... InSitu
Biologics ..... Insmed... Inspired Solar Systems ...
Inspire...
Insulet
Labs
... Intact Vascular... Intaglio... Intalio ... Intarcia
Therapeutics ...
Integenx... Integra Group Diagnostics... Integral Molecular .....
Integrated BioTherapeutics
.... Integrated
Diagnostics .... Integrated
Diagnostics InDi .... Integrated DNA Technologies ..... Integrated
Fuel...
... Integration Associates... Intelect
Medical
Intelleflex ... Intellia Therapeutics .....
Intellicyt
Automation Bio-systems ...
Intelligent Devices .... Intelligent Epitaxy Technology .....
Intellimedix ..... Intelliphage.... Intellirad
Control...
.Intellisense .... Intelomed ....Inter-4... Interactive Supercomputing
... Interdigital
Interlace ....
Intermagnetics General ...Intermolecular ... Intermune....
International Stem Cell ... Interrad Medical ..... IntersectENT ....
Intersense...
Intersystems ...
Intervalve.... InterVene .... Intevac.... Intra-Cellular Therapies
.....
Intralase ...... Intralytix .... Intrexon ..... Intrinsic Therapeutics
.... Intrinsity....
Introgen....
... Intuitive Biosciences .... Intuitive Genomics ..... Intuitive
Surgical.... Invenra ....
Invensense .... Inventev ..... Inverness
Innovations.... Invirsa ..... Invertix.... Invictus.... Inview
Technology....
Inviragen.... Invisage Technologies ....
....InvisionHeart .... Invision Medical ....
Invitae....
Invitrogen.... ...Invivosciences.... Invivo Therapeutics=
Holdings .... Invuity....
Inx Medical.... IoGyn .... Iomai.... ... Iomed....
IOmet
Pharma ..... Ion America Optics..... Ionic Materials ..... Ion
Torrent.... Iovance Biotherapeutics ..... Iovation.... Iowa Thin
Film....
Ipierian.... IPG Photonics.... ... Iquum
...Irhythm...
iRobot... Iroko...Ironbridge.... ... Ironwood....
... .... Irvine Sensors... .... biopolymer
. .... Ischemia Care.... iSee ..... iSIGHT
Partners
.....
Isis.... Island Ddata....
Isogenis.... Isomark.... IsoPlexis .... Isoray....
Isothermal....
Isthmus Biosciences ..... IstoTechnologies....
itaconix....
I-Therapeutix..... Itherxm Pharmaceuticals.... Itraumacare... .. Itseez
..... Itzbig ..... Iwalk
Jade Therapeutics ..... J&Y ... Janssen Biotech .... Janus Biotherapuetics ... Javelin Pharmaceuticals ... Javelin Semiconductor ... JDP Therapeutics ..... Jennerex ... Jnana Therapeutics ..... Joule Biotechnologies .... Jounce Therapeutics .... Joyent .... Joylux .... Joyn Bio .... Juno Therapeutics ..... Just Biotherapeutics
K2M .... K2 Therapeutics .... KAER
Biotherapeutics .... Kala
Pharmaceuticals ... Kaleido Biosciences .....
Kallyope ..... KaloBios Pharmaceuticals ..... Kalocyte .... Kalon
Biotherapeutics ..... KalVista Pharmaceuticals .... Karius ..... Karuna
Therapeutics ...
Karyopharm Therapeutics ... Kateeva
..... Kayo
Technology ..... KaZaK
... KC BioMediX ... KCI .... KDH Defense Systems
... Kebotix .... Keithley Instrument ...
Kelyniam ...
Kenall
Manufacturing
..... Kensey-Nash
... Kent Displays ... Kentucky
BioProcessing ....
KeraNetics .... Keros Therapeutics ..... Kezar Life Sciences ..... KeyW
.... Kilawatt
Technologies ... Kindara .... KinDex ... KindHeart ..... KineMed ....
Kinestral Technologies ..... Kineta ...
Kinetic
Concepts .... Kinex
Pharmaceuticals .... Kingbright .... Kior .....
Kips Bay
Medical ... Kite Pharma ..... Kitware ...
Kiva Systems ... KLD
Energy Technologies .... Klotho Therapeutics .... KMel
Robotics .... Knightscope
.....
Knome ...
Knopp
Neurosciences .... KNOW Bio ..... Know Labs .... KnuEdge ....
Koam
Engineering Systems .... Kodiak Sciences
.... Kolltan
Pharmaceuticals
...
Komoku ... Kona Medical .... Konarka ... Koning ...
Kopin
.. KOR
Electronics ...
Koronis Pharmaceuticals ... Kosan Biosciences ... Kosmetikos
....
Kovio ... KPI
Therapeutics (from Kineta)... Kraig Biocraft ..... Kratos Defense
& Security
Solutions
.... Kronos Advanced
Technologies ... Krystal Biotech .... KSE
... KSQ Therapeutics ..... Kultevat ..... Kura Oncology ....
Kumu Networks .... KVH
.. Kylin
Therapeutics
...
Kyma ....Kymera Therapeutics ..... Kymeta
... Kyn Therapeutics .... Kyocera
Solar .... Kypha ..... Kyras Therapeutics ..... Kyron Clinical Imaging
.... Kytopen
LAAMScience ... LaBelle
Associates .....
LabNow
...Laborie Medical Technologies ... Labrys Biologics ... Lacerta
Therapeutics ..... Lactic
Solutions ..... Laguna
Pharmaceuticals (formerly ChanRx) ..... La Jolla
Pharmaceutical
... Lake Shore Cryotronics .... Landec
.... Landos Biopharma .... Lantern
Pharma ..... Lantheus
...
Lantos
Technologies ... Lariat Biosciences .... Laser
Design .... Lasergen ..... LaserMax ..... LaserMotive
... Laser Tissue
Welding .... Lattice Biologics ..... Lattice
Biotech ....
Lawrie ... Lazarus Effect ..... LDR
Holding
..... Lead
Therapeutics
... LeafBio .... LeCroy ... LED Lighting
Fixtures
... Lehigh
Technologies .... Leica Microsystems
.....
LetoSolutions .... Lexicon
Genetics
... LexaGene ..... Lexicon Pharmaceuticals ... Leuko .... Leyden Energy
...
Libra
BioSciences .... LifeCell ... LifeGen
Technologies ...
Life Image ... LifeMine Therapeutics .... LifeSprout ....
Life Technologies
....
Ligand
Pharmaceuticals ....Ligon Discovery ... Lightpointe
... Light Sciences Oncology ... LightWorks Optics
....
Lilliputian Systems
.... Lily Robotics ..... Linares Management
Associates
.. Lingotek
... Linnaeus Therapeutics .... LinQuest .... Lionano .... Lion
Biotechnologies ..... Lipocine ....
LipoScience
...
Liquid Biotech ..... Liquidia
Technologies ...
Liquid Light ...
Liquid Metal
Battery ...
LiquidPiston ... Liquid Robotics ... Liquid X Printed Metals
....
LiQuifix ...
Lithium Technology
... LiveData ... . LiveLeaf
Bioscience .... LKC Technologies ... Locana.... Locus Biosciences ....
Lodo
Therapeutics .... Logical
Therapeutics
... LogicBio Therapeutics ..... Logos
Tech
... Lohocla Research
.....
Lombard Medical ..... Longeveron ..... Longeviti .... LonoCloud .....
Lookingglass ..... Loon Medical
..... Lotus Tissue
Repair
...
Loxo Oncology ... LPath Thera .... Lq3 Pharmaceuticals ....
LS9
...
Luca
Technologies .... Lucerno Dynamics .... Lucidux ...
Lucigen
.... LumaSense Technologies .... Lumena
Pharmaceuticals .... Lumen Bioscience .... Lumencor
... Lumense .... Lumera ... Lumicell Diagnostics
... Luminar Technologies ..... Luminary Micro ...
Luminex .... Luminus Devices ... Lumisyn
..... Lumitex
... LumiThera .... Lumos Pharma .... Luna Innovations
... Luna Technologies
... Lung Therapeutics .... Lutonix
... Luxtera
... Lycera ... LyGenesis ..... Lyncean ..... Lyndra
Therapeutic ... Lynntech ... Lynx Biosciences ... Lyra Therapeutics
..... Lysosomal Therapeutics ....
Lytro Therapeutics
M3 Biotechnology .... MabVax .... MacAulay-Brown
..... Macrochem ...
MacroFab ..... Macrogenics
... Macrolide Pharma ..... Macrophage Therapeutics ....
Madison
Vaccines .... Madrigal Pharmaceuticals ..... MagBioSense ..... Magenta
Therapeutics ..... Magic Leap
..... MagneMotion ...
Magnesium Development ..... Magnetek ... Magnolia
Medical
Technologies .... Magnolia Optical
Technologies
... Magnolia Solar ... Mainstay Medical International ......
Mainstream Engineering ... Major
Pharmaceuticals .... Mako Surgical
... Manhattan Scientifics ..... Mantra Bio .....
>Manufcturing Techniques ..... MapInfo
...MAP
Pharmaceuticals
... Mapp
Biopharmaceuticals .... Marathon Pharmaceuticals ..... Marcadia
Biotech
... Marina Biotech ... Marinus
Pharmaceuticals
... Maritime Applied Physics ....Marker Therapeutics ....
Marrone Bio Innovations
....
Martek Biosciences ...
Mascoma ... Mashery
... Mason Box ... Masten Space Systems
... Masterson Industries .... Mast Therapeutics
(formerly
ADVENTRX) .... Material Sciences ... Material
Technologies ... MathStar ... Mati
Therapeutics .... Matouk
Textiles ... Matritech ... Matrix Product Development
.....Matrix
Research ....
Matrix Sensors ... Maverick Therapeutics .... MAX
BioPharma
...
MaxCyte ...... Maxdem
... Maxpower ... Maxygen ....
Maze Therapeutics .... MBio Diagnostics
.... MC10 .... MCube .... M
Cubed Technologies .... MD Biosciences ..... MDSolarSciences
... Mebias Discovery ..... Mechanical
Technology
...
Mechanology ... Medafor ...
Medarex ...
MediBeacon .... Medicago USA .... Medical21 ..... Medical Cyberworlds
.... Medical
Device Logistics ...
MedicaMetrix... Medgenics ..... MediciNova .....
Medicool
Technologies .... MedImmune ..
Medina Medical .... Mediomics .... Medior Therapeutics .... Medis
... MEDITE Group .... Medivation ... Mednology Solutions ....
Medrobotics ...
MedShape .... MedSocket (formerly 1CDS) ...... Medsphere Systems .....
MedTel ..... MEI Pharma
..... Meka .... MELA
Sciences .... Melinta Therapeutics .... Melior Discovery .... Memjet
...Memry ...
Memsic ... MEMS Optical...Menlo Therapeutics ..... MER
...
Mercator Therapeutics ... Mercury Computer
Systems .... Merganser Biotech ....
Merge
Technologies ... MeriaGTx ..... Meridian Bioscience
... Meritage Pharma ..... Merkatum ... Merrimack
Pharmaceuticals
... Meryx .... Mersana Therapeutics ... Mesa
Photonics ... Mesocopic
Devices ... Metabasis ... Metabiota .... Metabolic Solutions
Development .... Metabolex .... Metabolix
... MetaCarta ... Metacrine .... Metactive Medical
.....
Metal Oxygen
Separation Technologies ... Metamark Genetics ...
MetaModix
... Metavention ..... Metompkin Seafood .... MetroLaser ...
MGC
Diagnostics
...
MIACH Orthopaedics ..... Misaole .... Micell
Technologies
... Michelman ... Micracor .... Micrel ... MicroCoating ...
Micracor ....
Microbe Detectives
... Microbia ... Microbot Medical ... Microfluidics International
(Microbia)
... MicroGreen
Polymers .... MicroIslet ...
Microlin Bio ....
MicroMask ...
Micronics ... MicroOptical (New
Mexico)... MicroOptical
(Massachusetts) ... MicroOptx ..... MicroPower Technologies
...
MICROrganic Technologies .... MicrowSat
Systems .... Microscopy Innovations ..... Microstaq
... MicroTransponder ..... Microvision ... MicuRx
Pharmaceuticals
.... Midori Renewables
..... Mid Valley
Industries
... Millendo Therapeutics (born as
Attercor) ..... Million Concepts ..... Miltec .... MiMedx Group ....
MimiVax ....
Minerva
Biotechnologies
... Minerva Neurosciences .... Minerva Surgical
.... Minimally Invasive Devices .... Minnesota
Thermal Science ..... Minnetronix ... MIOX ..... Mirador Biomedical
... Mira Dx ... MiRagen
Therapeutics .....
Miramar Labs .... Mirati Therapeutics ..... miRecule .... Mirimus ...
Mirina ... Mirna
Therapeutics.... Miromatrix Medical ...
Mirus Bio ....Mirum Pharmaceuticals ..... Mission Bio ..... Mission
Research ...
Mississippi Polymer ... Mithridion ...
Mitochon Pharmaceuticals ..... Mnemosyne
Pharmaceuticals ...
Mobile Robots ... Mobius Therapeutics ..... Moderna Therapeutics ....
Modern Meadow .... Modern Technology Solutions
.... Moduline Systems .... Modumetal ..... MOgene Green Chemicals ....
Molecular
Biometrics
... Mohawk
Innovative Technology ..... Molecular
Detection ... Molecular Diagnostics .... Molecular Imprints
... Molecular
Insight
Pharmaceuticals ... MolecularMD ... Molecular
Sensing ...
Molecular
Templates
.... Moleculin Biotech ..... Molten
Metal .. MoMelan Technologies ... Momenta
Pharmaceuticals ... Monebo ... Monogram Biosciences
.... Monteris Medical ..... Morphic Therapeutics
.....
Morphormics
... Morphotek
...
Morris
Innovative Research ... Mortara Instrument ...
MortaSecurity .... Motif ... Motricity
... Motus Therapeutics .... Mound Laser
& Photonics Center ..... Movia Robotics ..... Moximed .... MPP
Group ... MPSP ...
MSNW ....
Mudawar Thermal
Systems
.....
Munksjo Paper ... Muons ... Muse bio .... Myco
Technology
....
Myocor
... MyoKardia
...
Myomo
... Myonexus Therapeutic ..... Myovant Sciences
.....
Myriad Genetics
...
Myriant
Technologies
... Mystic Pharmaceuticals
N12 Technologies
... (N30 Pharmaceuticals) now Nivalis Thera .... NABsys
... Nalas
Engineering ....
Nammi Therapeutics ..... NanOasis Technologies
... NanoBio
...
Nanobiosym ... Nano-C ... NanoCellect (formerly NanoSort)
.....
Nanocomp Technologies ...
NanoCoolers ... Nanocopoeia ... NanoCor Therapeutics
...Nanodynamics (Buffalo) ... Nano DX ..... Nanodynamics
(NYC)...
NanoeXa
.... Nanofiber Solutions ... Nanogen ... NanoGraf (formery SiNode)
..... NanoGram .... nanoGriptech
..... NanoGuard Technologies .... NanoH2O ...
Nanohmics ... NanoLab
... NanoLite Systems ... NanoLogix ...
NanoLumens
..... Nanomaterials
Research
... NanoMatrix ... NanoMedex ... NanoMedicalSystems
...
NanoMedical Systems .. Nanomix ... nanoMR ..... Nanophase
Technologies
... NanoPhotonica ... Nanopore Diagnostics ..... Nanoptek
... Nanoramic
Laboratories (formerly FastCap Systems) ..... nanoRETE .... Nanoscale
Components ...
Nanoscale
Materials
... Nanosolar ...
Nanosonic ... Nanospectra Biosciences .... Nanosphere ... NanoSteel
...
Nanostim .... NanoString
Technologies .... Nanosys ...
NanoSystems ... Nano Tailor ... Nanotek Instruments
.....
Nano-Terra ... Nanotherapeutics ..... NanoTune Technologies
... Nanova
....
Nanovation
Technologies ... NanoVault Medical .... NanoVibronix ... NanoViricides
... NanoVision Diagnostics .... NantCell
..... Nantero
... Napo
Pharmaceuticals ... NantKwest ..... Narus
Biotechnologies ..... Nascentric
... Nastech
Pharmaceutical ... Natera .... National Technical Systems
..... Natural Molecular Testing ..... NaturalNano ...
Nature's
First .....
Natus Medical ... Naverus ... Navidea
Biopharmaceuticals ... Navini Networks
... Navire Pharmaceuticals .... Navitor Pharmaceuticals ....
Navmar Applied Sciences
... NBD Nanotechnologies ....NCD Technologies
.... nContact
Surgical ...
Neah Power ... Near Infinity .... Neato Robotics ... Necci
.... Nektar
Therapeutics ... Nekton
Research
.... NemaMetrix .... NeoChord ... Neogen
.... NeoGenomics ..... Neograft
..... NeoLight ..... Neon Therapeutics ....
NeoPhotonics ... Neoprobe
...
Neos Therapeutics ..... NeoSync ..... Neothetics .... Neotron
...
NephroGenex .... Nereus
Pharmaceuticals ... Nest .... Netcentric .... Netezza ...
NetLogics
Microsystems... Netspeed Systems ...... Net Watch
Solutions
..... NetworkFab
...
NeurAccel
Biosciences ...
Neurala .... Neural Analytics .... Neuralstem .... Neuraly
..... Neuraptive
Therapeutics .....
Neuro
Amp .... Neurobiological
Technologies
...
NeuroChaos Solutions .... Neurocrine Biosciences
...
NeuroDx Development ... NeuroEM .... Neurodyne Medical ...
Neurofluidics ....Neurogastrx .... Neurogen
... NeurogesX ...
Neurognostics .. NeuroHabilitation .... NeuroLogica
.... NeuroLutions ..... NeuroMap
... Neuro Kinetics ....
NeuroMetrix... Neurona Therapeutics .... Neuronetics .
Neuronex .. NeuroOne ..... NeuroPace
...
NeuroPhage
Pharmaceuticals
... Neuron Systems ... NeuroPointDX
..... Neuroptix
... Neuroscience .... NeuroSigma .... NeuroTek .... Neurotrack ....
NeuroTronik .... Neurotrope ..... Neurovance
... NeuroVigil ...
Neurovascular
Diagnostics ..... NeuroVision Imaging .... NeuroVista ....
NeuroVive
.... NeuWave
Medical ...Nevro ... New Dominion Enterprises ..... NewLeaf
Symbiotics .... NewLink Genetics
.... Newlink genetics england ... biolabs ...
new
era technology ... New Haven Pharmaceuticals ... Nexant
...Nexbio
... NexImmune .... NexPlanar .... NextCODE Health ....
NextCure ..... Nextio ....
NEXTracker
....Nextreme Thermal Solutions ... NextStep Robotics .....
Nexus
Biosystems ..... NG1 Technologies .... NGM Biopharmaceuticals .... Nico
..... Night Vision ...
Nimblegen Systems ... Nimble Storage .... Nimble Therapeutics
.... Nimbus Discovery ... Nimbus
Therapeutic
.....
Ninepoint
...Niowave ... NIRvana Sciences .... Nitero....
Nitric Biotherapeutics
....Nitricgen ... Nitride Solutions .... Nitrogenics .....
Nitromed ...Nitronex
... Nivalis Therapeutics formerly N30 Thera ..... NKT
Therapeutics ...
Nlight ... NMT Medical .... Noah
Technologies ....
Noble Fiber
... Nocion Therapeutics .... Nohla Therapeutics
.... Noivatone .... Nok Nok
Labs .... Nomadics .... NONA Composites .... Noninvasix ....
Nonvolatile
Electronics .... Nora Therapeutics .... Norian ... NorMedix
.....
Normoxys
.... Norse .... Northeast Photosciences
... Northstar Medical
Radioisotopes .... Northstar Photonics...
Northwest Biotherapeutics .. Norwich Technologies ....
Nostopharma .... Notice
Ttechnologies ... .Novacea
... Novalar Pharmaceuticals ... Novalux
... Novan
Therapeutics .... NovaScan
... Nova Synthetix .... Novatek ... NovaTorque
... NovaTract
Surgical
... Novavax .... Novazyme Pharmaceuticals ..... Novecon
Technologies ... Novella
Clinical
.... Novelos
Pharmaceuticals
... Novelos Therapeutics ... Noveome Biotherapeutic
.....
Novian Health .... Novira
Therapeutics ...
Novocell ... Novogy
... Novomer ...
Novophage ... Novo Sol-u-tions MD .... Novosource ...
Novozymes .... Novus Biologicals ....
Noxilizer
... Nox Technologies ... NP Photonics ...
NPS Pharma ..... NRGindependence ..... NSS Labs
..... Nucelis
.... Nuclea
Bioechnologies ... Nufern .... NuGEN Technologies ..... NuMat
Technologies ..... NuMedii
.... NumereX .... NUMiX Materials ..... NuPathe .... Nurel
(now PeriphaGen) .... Nurix Therapeutics ... Nuron
Biotech ... Nutrabiotix
... Nutrient Recovery and Upcycling .... NuVant
... Nuvaira .... NuVascular Technologies .... Nuve .....
Nuventix ...
Nuvera Biosciences ... Nuvera Fuel Cells.. . Nuvotronics
.....
Nuvox
Pharma ..... Nu Waves ..... NxThera ... Nvision
Biomedical
Technologies ..... NZ
Applied Technologies
Oak-Mitsui .... Oasys ...
ObjectVideo
... Obsidian Therapeutics ..... OBS
Medical ... Ocarina Networks ... Ocata Thera ...
Occipital
....
Ocean Power
Technologies
... Ocean Renewable Power .... Ocera Thera .... OCI ...
Ocugen ..... Ocular
Therapeutix
....
Oculeve
... Oculogica ..... Oculus ... Oddpost
... Odyssey Systems
Consulting Group ... Oil Chem
Technologies ... OLEDWorks .... Omeros
... OmniGene Bioproducts ... OmniGuide ...
OmniLytics
... Omniox ..... OmniSonics Medical Technologies
... Omnis
PharmaRebiotix .... Omni
Water Solutions ... Onboard Dynamics .... ONCE Innovations
.....
OnChip
Power .... Oncobiologics ..... OncoCyte
.... Oncogenex
... Oncolmmune ..... Oncolinx .... Oncolix ..... Oncolytics
Biotech
...
OncoMed
Pharmaceuticals .... OncoNano Medicine .... Onconova
Therapeutics
...Oncoscope
...
OnCore Biopharma ..... OncoResponse ..... Oncorus .....
OncoSec
Medical
.... OncoTartis ...... Oncothyreon
... Oncovista Innovative Therapies ..... Oncternal
Therapeutics ... Onduo ..... One
Resonance Sensors .... Onexio Biosystems .... Onko Solutions .... ONL
Therapeutics ....
On-Q-ity .... Onspira Therapeutics .... On Target
Laboratories
.... Ontela ..... On-X
Life
Technologies ....
Onyx
Pharmaceuticals ... Oorja
Protonics .... Open Algae ... Open Monoclonal Technology
.....
Open Silicon
... OpenWater
Power .... Opertech Bio ..... Opexa
Therapeutics
... OpGen ... OPNET Technologies
... Opsonix .... OptTek
Systems ... Optelecom ...Optelecom-NKF ... Optherion ...
Optical
Concepts .. Optigain .. Optimal Technologies ... Optimus
Technologies .... OptiNose .... Optivision
...
Optofluidics ... OptoLum ..... Optonicus .... Opto Technology
...
Optomec
....
OPX
Biotech
... Oragenics .... OraMerix
... Orasi Medical ... OraSure
Technologies ....
Orbital
Technologies
... Orbotix .... Orchard Therapeutics .....
Orchestra BioMed .... Orchid
Cellmark
... Oregon Iron
Works .... Orexigen
Therapeutics
... Organic Research .... Organogenesis ...
Organovo
..
ORIC Pharmaceuticals ..... Oricula Therapeutics .... Origin
Medsystems ..... OriginOil
... Orion Energy Systems ... Orion Genomics ...
Ormet
Circuits ... Oroboros Bio .... Orologic...
OrphoMed ..... Ortel ...
OrthoAccel
Technologies ... Ortho Kinematics
.... Oryx Technology ...Oscient Pharamceuticals ...Oscilla
Power
.... Osiris
Therapeutics ... OSI Pharmaceuticals ... Oso Biopharmaceuticals
Manufacturing .... Osprey Medical ....
Ossianix
... OSSIO ..... Ostendo Technologies ...
Osteotech ... Osterhout Design Group .... OtoNexus Medical
Technologies .... Otonomy .... OtoSense
.... Ottomatika .... Outset Medical .... OvaScience ...
>Ovid Therapeutics ..... Oxalo Therapeutics .... Oxford
Performance Materials ... Oxis International .... Oxygen
Biotherapeutics
P3I ... Pace Packaging .... Pacific Biosciences
.... Padlock Therapeutics .... Pain Therapeutics ...
PaizaBio .... Palvella Therapeutics ... Palantir Technologies ....
Palleon Pharmaceuticals ....
Palmaz Scientific ..... Palmer
Labs
...
Paloma Pharmaceuticals ... Panacea Solutions ....
Panacos
... Pandion ..... Pandromics ..... Pan Genome Systems .... Panomics
..... PanTheryx .... Paper
Battery ....
PapGene .... Parabricks .... Paradigm Diagnostics
.... Paradigm Sensors
... Paradromics ..... ParaGen Technologies ..... Paragon
Bioservices ..... Paragon Dynamics .... Paragon Space
Development ...
Paragonix Technologies .... Parasol Therapeutics
... Paratek
Pharmaceuticals .... Parexel International .... Parhelion .... Parion
Sciences
... ParkerVision .... Partner Therapeutics ..... Partpic ....
Passage Bio ... Passport
Systems ... Pasteuria Bioscience ... Pathfinder ...
PathoGenetix
... PathoVax ..... Pathway Genomics .... PatientStream ...
PatientWise ...
Patton Medical Devices ... Patton Surgical .... Pavilion
Technologies ... Pax Streamline ... PaxVax ...
PDI Therapeutics ..... PDL
BioPharma ... PDS Biotechnology ..... Pearl
Therapeutics
... Pear Therapeutics ..... PECA Labs
.... Pediatric Bioscience .... Peerless Technologies .... Pegasus
Sustainability Solutions ....
Pelican
Products ..... PellePharm .... Pellion
Tech ... Peloton Therapeutics ..... Peninsula
Pharmaceuticals ..... PennAlt Organics ..... Penumbra .....
PeproMene Bio .... Peptimed
... Peptilogics .... Peptimmune
... Perceptive Navigation ..... Perceptive Sciences
... Perceptron ....
PercipEnz
Technologies
... Peregrine Semiconductor .... PeriphaGen .... Permeon
Biologics
...
Perosphere .... Perscitus Biosciences ... Perseon .....
Persimmon
Technologies ....
PersonalBee ... Personalis ...... Personal Genome
Diagnostics
.... Pervasis Therapeutics
... Pervasive
.... Petra Pharma ..... Pfenex ...
Pharmacyclics
.... PharmaJet .... PharmAkea Therapeutics ....
Pharmasset
... PharmAthene
... PharmatrophiX .... PhaseBio
Pharmaceuticals .... Phase Bioscience ... PhaseRx ....
Phigenix
..... Phoenix (formerly Phoenix Nuclear Labs) ..... Phoenix
Biotechnology .... Phoenix
Nuclear Labs ...
Phoenix Science .. Phononic
Devices
... Photobit ... Photolitec .....
PhotoMedex
... Photonics
Innovations ... Photon-X ....
PhotoSonix Medical .... PhotoThera
...
Photronics ... Phoundry Pharmaceuticals .... Phraxis
.... Phrixus
Pharmaceuticals ..... Phurnace
Software ... PhylloTech ..... Phylonix
.... Phylos Bioscience ..... Physcient .... Physical
Optics... Physical
Sciences
... PhysioGenix
... PhysioSonics ... PhytoTech ... Picolight ....
Picometrix
... Piedmont Biofuels .... Pieris Pharmaceuticals ..... Pika
Energy ... Pilus
Energy ....
Pinger
...
Pinnacle Technology ... Pioneer Surgical
Technology .... Pionyr Immunotherapeutics ..... Pivot
Bio ..... Pixelligent .... Pixel
Optics .. Pixim ... Pixtronix ... Plakous Therapeutics .....
Planar Energy
...
Planar Systems ... Planet Labs .... Plano Microwave ..... Plasan ...
PlasmaTech Biopharmaceuticals .... Platelet
BioGenesis .... Platypus
... Play-i
.... PLC
Medical Systems
... Plextronics ... Plexxikon
... Pliant Therapeutics .... Plug
Power ... Pluromed ... PLx Pharma ..... PLX Technology ....
PMT
.... PMV Pharmaceuticals .... PneumRx .....
Point Source .... Polarean ..... Polatis
.... Polychromix
...
Polyera ... PolyMedica ... PolyMedix ... Polymer
Technology
Systems ... Polynoma ..... PolyNova .... PolyPlus ... PolyRemedy ...
Polysciences ... Polystor ... Portola
Pharmaceuticals ... Poseida Therapeutics .... Possis
Medical ... Pothole Pros ... PowerGenix ...
Powerlight
... Power
Precise Solutions ... PowerVision ... Pozen ... PQ
Bypass .... Prairie
Technologies ..... Pranalytica ... Praxis Biotechnology .....
Precipio ... Precision Biopsy
... Precision BioSciences
.... Precision for Medicine .... Precision Genome
Engineering .... Precision Ocular Metrology ..... Precision Optics
...
Precision
Therapeutics (now Helomics) .... Precision Virologics .... Precisive
Surgical .... Predictive
Biosciences
... Pregmama ..... Prellis Biologics .... Presage
Biosciences
... Presidio
Pharmaceuticals
.... Pressure BioSciences
... PreTalen ..... Prevail Therapeutics ..... Preventice .....
Prevention
Pharmaceuticals ....
Prieto Battery ..... Primary Data ..... Primera
Biosciences ... Primordial .... Primorigen Biosciences
... Primus Power .... Princeton Satellite
Systems ..... Principia Biopharma ....
Prism
Solar Technologies .... Procept BioRobotics ..... ProCertus
BioPharm
... Processa Pharmaceuticals .....
Proclara
Biosciences (formerly
NeuroPhage
Pharmaceuticals) .... Procyrion .... Profectus BioSciences .
.. Progenics
Pharmaceuticals
... Progenity .... Progeny Systems ..... Prologic
...
Promedior
...
Promega ..... Promentis .... Prometheus Laboratories
.... Pronutria ..... Propagenix ..... Propeller
Health ....
Propulsive Wing
.... ProstaGene ....
Protagonist
Therapeutics .... Protein Foundry ..... Protein Sciences
... ProteinSimple (formerly Cell
Biosciences) .... Proteon Therapeutics
...
Proteostasis
Therapeutics
... Proteotech ... Proteus
Biomedical
... Proteus Digital Health .... Protez Pharmaceuticals
.... Prothena .... ProThera Biologics ...
Proto Labs ... Proton Energy Systems ...Protonex ..
Prototype
Productions .Provagen ... Provenance Biopharmaceuticals
... Provention Bio .... Proventys
... Provista Diagnostics .... Pryor Medical Devices .....
PsiKick
..... pSivida
... PTC Therapeutics
.... Pulmatrix ... Pulmonx .... Pulmotect ..... Pulse
Aerospace .... Pulse
Electronics ....
PulseTherapeutics .... Puma Biotechnology ..... PUR
Biologics ..... Pure Bioscience .... Purfresh
... Purillume ..... Pursuit Vascular ... PurThread
.... PvP
Biologics ..... Pyran ... Pyxis Oncology
Qcept Technologies .... Qcue .... QD Vision
...
QED ... qFuzion ..... Qioptiq
... QM Power
... Qpex .... QPixel ... QR
Pharma
... QSpex .... Qteros
... QuaDPharma .... Quadra-Aerrow International ...
Quadraspec
...
Quad Technologies .... Qualcomm ... QualityMetric
...
Qualtech Systems ....
Qualtré ... Quanterix
... QuantRx Biomedical
.... Quanttus .... QuantTera .... Quantum Circuits ..... Quantum
Epitaxial
Designs ... Quantum Fuel Systems... Quantum Logic
Devices
... Quantum Materials .... QuantumSphere
.... Quantum Xchange .... Quark
Biotech ... Quark
Pharmaceuticals ... Qubitekk ..... Quentis Therapeutics .....
Quick–Med
Technologies .... Quid ..... Quidel
... Quincy
Bioscience
... Quintessence Biosciences ... Quorum
Systems
Radant Technologies ... Radiabeam Technologies
... Radiance Technologies .... Radiant Photonics...Radiation
Monitoring Devices
... RadioMedix ... Radius
Health ....
Rafagen ... Rainbow Organic Farms ... RainDance
Technologies
...
RainStorm ...
Rain Water Solutions ... Rallybio ..... Raland Therapeutics .... RaNA
Therapeutic ...
RAN Biotechnologies .... Range Fuels
... Rapamycin Holdings ..... RaPharmaceuticals
... Rapid Diagnostek ... Rapid
Micro Biosystems
... Rapiscan ... RareCyte ..... Raser Technologies
.... Raydiance ... Raydiant Oximetry .... Raymond
.... Raze
Therapeutics
.... RE2
.... Ready Robotics ..... Reata Pharmaceuticals .... Rebellion
Photonics .... Rebion ..... Rebiotix ....
Receptor Logic ...
Receptos
..... Recodagen ...
Recombinetics
... ReconRobotics
.. Recovery Engineering ..... Recro Pharma ....
Recursion
.... Redox Power
Systems .... Red
Rock
Biofuels .... RedShift BioAnalytics .... Redwood Robotics .... RedZone
Robotics .... RefleXion
Medical .... Refuge Biotechnologies .... Regado
Biosciences
... ReGear Life Sciences ..... ReGen
Biologics ... Regenerative
Medical Solutions ..... Regenerative Sciences ... Regentys
(formerly Asana Medical) .... Regenxbio
....
Regulus Therapeutics ... Rehabtics .... Relay Therapeutics
..... ReliantHeart ....
ReliefBand Technologies ..... Relievant Medsystems
..... Relypsa .... Remedy Plan Therapeutics .... Remedium
Technologies ... RemoteReality .... Rempex
Pharmaceuticals .... Renaissance Services ..... Renegade
Materials .... Reneo
Pharmaceuticals ..... Renerva ..... ReNeuroGen .... Renewable
Alternatives
... Renewable Energy Group .... Renmatix .....
Renovacor
..... RenovoDerm ..... Renovia .... Renovion .... Renovis ...
Rentech ... Replidyne
...
Repligen .. Replimune Group .... Research Frontiers
.. Research Innovations ..... Resolve
Therapeutics
... Resolvyx
Pharmaceuticals ... Resonetics ..... Respicardia
... Respira
Therapeutics .... Response Genetics
...
Restoration Robotics ..... resTORbio ..... Restore Medical ... Retectix
..... Retek
...Rethink
Robotics ... Retia Medical .... Retriever
Technology
.... RetroSense Therapeutics ..... Reva Medical
... Revance Therapeutics Pharmaceutical ....
Revegen
... ReVision Optics ....
ReVision
Therapeutics .... Revitope Oncology ..... ReVivo Medical
....
RevMedx .... ReVolt Tech
... Revolution
Medicines .... ReWalk
Robotics (Israel) .... Rexahn
Pharmaceuticals
... Rex Computing ..... RF Code ...
RFMicron
.. RFS Pharma ..... RF Surgical.
.... Rgenix .... Rhenium
Alloys .. Rheos Medicines ..... Rheostat
Therapeutics ..... Rheumco .... Rhevision
... Rho ... Rhythm Pharmaceuticals ... Rhythmia
Medical
... Ribometrix ....
RiboNova .... Ribon Therapeutics ..... Rib-X
Pharmaceuticals ... Rice Technology ..... Ridgetop
Group ... Rigel Pharmaceuticals .... RightEye ..... RightHand
Robotics .... Rinat
Pharmaceuticals
.... Rinovum Women’s Health ..... Rio Grande Neurosciences .....
RipCode ... Rite
Solutions .... Ritter
Pharmaceuticals ..... River Vision Development ..... Rive Technology
... RJA Dispersions ... R.L. Phillips ...
RMH
Sciences ...
Robb Surgical Devices .... Robopsy ...
Robotic FX ... Robotics VISION
Technologies ..... Robotic Technology
... Rocket Pharmaceuticals .... Rockwell Medical
..... Rocky Research .... Rodeo Therapeutics ..... Rodin
Therapeutics ... Roka
Bioscience
.....
RoosterBio .... RootPath .... Rosina Food Products ....
Ross Valve ..... Rotational
Medical .... RotoMetrics ..... RoverMed Biosciences ..... Rowbot
Systems .... Royole ..... RQx
Pharmaceuticals .... RRE
Solar ....
Rubicon Tech ...
Rubigo Therapeutics .... Rubitection ..... Rubius Therapeutics ....
RubrYc Therapeutics ..... Rules-Based
Medicine
... Rushford Hypersonic ... Ruud Lighting ..... RxFunction
...
RXi Pharmaceuticals
...
RxMedic .... Rypos
S2 ... Sadasis .... SafeShot .... Saffron
Technology
.... Sage
Electrochromics ... SADAR 3D .... Sage Science ... Sage
Therapeutics ...Sakti3 ... Salarius
Pharmaceuticals .....
Salient Surgical
Technologies
... Salix
Pharmaceuticals ... Salutaris Medical Devices ..... SAM Medical ....
Sancilio
Pharmaceuticals .... Sand 9 .
.. Sandia Biotech .... Sangamo
Biosciences
... Sangart
... Santalis Pharmaceuticals ..... Santarus .... Sanuwave
Health
.... Sapheon .... Sapphire
Energy ....
SARbarcode .... Sarda
Technologies ...
Sarepta Therapeutics .... SatCon
Technology ...
Satori Pharmaceuticals
.... Savara Pharmaceuticals .... Savi ...
SBH
Sciences ...
Scanadu ..... Scholar Rock .... Sciaderm ..... SciClone
Pharmaceuticals
... Sciencescape ..... Scientific
Conservation .... Scientific Research ...
Scientific
Solutions ... Scientific Systems ... SciFluor Life Sciences ... Scilex
Pharmaceuticals .... Scinovia ..... Scioderm .... SciQuest ...
Scopic Software
... Scout Bio .... scPharmaceuticals ..... Scynexis ...
SD Catalyst
Group ... SDL .. SeaChange ...
Seacoast Science
... Seahawk Biosystems ... Seahorse
Bioscience
... Seaside Therapeutics .... Seattle BioMed .....
Seattle
Genetics
...
Seattle Medical Tech .... Sebacia .... Second Genome ....
Second
Sight Medical
Products ... Securboration ..... Secure
Computing ... Sedia Biosciences ..... Seeo
....Segetis ... S.E.G-WAY Orthopaedics .... Seldon
Labs ... Selecta Biosciences
... SELLAS Life Sciences Group .... SeLux
Diagnostics .... Sema4
Natalis
..... Semiconductor
Laser ... SemiProbe ... Semler
Scientific
.... Semma Therapeutics .... Semnur
Pharmaceuticals .... Semprius ... Semprus
BioSciences .... Sencera International ...
SenesTech .....
SenGenix ....
Senior Scientific ..... Seno Medical
Instruments .... Senomyx
... SensAble Technologies ... Sense .... Sense
Diagnostics
....
Senseonics ..... Sensintel .... Sensiotec ...
Sensors
Unlimited
... SensorTran ... Sentelligence
... Senti Biosciences ..... Sentient
Technologies ..... SentreHEART ..... Sepracor
... SeprOx .... SeQual Technologies ... Sequella ...
Sequel
Pharmaceuticals .... Sequenom ... Sequenta ...
Sequent
Medical
.... SeraCare Life Sciences ... Seragon
Pharmaceuticals .... Seraxis ..... Seres Therapeutics (formerly Seres
Health) .... Serenex
... Sermonix
Pharmaceuticals .... Servergy .....
SetPoint Medical .... Seurat Therapeutics ..... Seventh Sense
Biosystems ...
SGB
Biofuels ..... SGX
Pharmaceuticals ...
Shamrock Energy ... Shape Pharmaceuticals ..... Shape Security ....
Shapeways .... Sharklet
Technologies ..... Sharp Edge Labs ..... Sherlock Biosciences
Shift Labs ..... Shift Pharmaceuticals ..... Shiloh
Labs ....Shine
Medical Technologies
... Shore
Thing Shellfish .... Shuttle
Pharmaceuticals ..... Si-Bone .... Sicel Technologies ...
SiCortex
... Sideris Pharmaceuticals ..... SI
Diamond Technology .... Sienna Biopharmaceuticals ..... Sierra Energy
..... Sierra Monolithics
... Sierra Nevada ...
Siga Technologies ...
SiGe Semiconductor ... Sigilon Therapeutics ....
Sigma Labs
(NM) .... Sigma
Technologies .... SignalFX (formerly Signal Fuse) ..... Signal Genetics
.... Signature
Genomic Laboratories
... Sila Nanotechnologies .... Silarus Therapeutics
.... Silatronix ..
Silent
Power ... Silicon Biosystems Menarini ..... SiliconBlue
....
Silicon Laboratories ...
Silicon
Mountain
Design .. Silicon Space Technology .... Silk .... SilkTech
Biopharmaceuticals ..... Silk Tech .... Siluria
... Silverbrook
... Silverback ..... Silvergate Pharmaceuticals .... Silver
Spring Networks
... Simbol Materials ... Simply Incredible Foods ... SiMPore
...
Simulation
Technology and Applied Research ... Simulution
... Singlera Genomics ..... Singulex ... Sinmat
... SiNode Systems .....
Sintact Medical Systems
..... Sion
Power
... SiOnyx ... Sioux Manufacturing ...
Sirga Advanced
Biopharma .... Sirion Therapeutics ...
Sirnaomics ..... Sirna
Therapeutics ... Sirtris Pharmaceuticals ... Sisu Global
Health
..... Sitari Pharma .....
Skybox Imaging .... Skyhawk Therapeutics ..... Skyline Medical
....
Skyonic
... SLI .. SLIPS Technologies .....
SmartCells
... Smart Modular
Technologies ... SmartSpark Energy Systems ...
Smart
Structures .... Smart Wires ..... SmartZyme BioPharma ....
Smisson-Cartledge Biomedical ...
Smooth-Stone
...
SNP Bio ..... Socrates Health Solutions .... Soft Machines
....
Soft Robotics ..... SoftSwitching
Technologies
... Soft Tissue
Regeneration ... Soladigm (now View) ..... SolAero
Technologies ..... Solaicx ....
Solais Lighting
....
Solana Surgical ..... SolaranRx ..... SolarBridge
Technologies ... Solar Connection ....
Solarea .....
Solaria ...
Solarmer
Energy ...
Solar Power Technologies ... SolarWinds
... Solazyme
... Solexant ... Solexel ... SolFocus ... Soliant
... Solid Biosciences .... Solid Concepts ..... SolidEnergy
....
Solidus Biosciences
..... SolidWorks
... Soliris .... Soliton ..... Solixia
... Solix
Biofuels
... SolMap
Pharmaceuticals ... SoloHealth ... Solomon
Technologies
... Solo Power .... Solstice Biologics .... Soluble Therapeutics ....
Solx ....
Solyndra ... Soma .... SomaDetect .... SomaLogic
.... Somatic Labs
..... Somaxon
Pharmaceuticals .... Somerset Therapeutics .... Somna Therapeutics ...
Sonalysts ...
Soneter .... Sonex Aircraft ... Sonitus Medical
... Sonivate ..... SonoSite
... Sonovex .... Sontra Medical ... Sonus
Pharmaceuticals
...
Sophiris
Bio .... Sophono ..... Soraa .... Sorrento Therapeutics ....
Soteira
... Sostena .... Sotera Wireless ... Sound Pharmaceuticals
.....
Sourcefire
... Source MDx
... Southwall Technologies ... Southwest Windpower
...
Space Dev ...
Spaltudaq ... Spansion .... Sparkbuy ..... SparkCharge .... Spark
Therapeutics ....
Sparo Labs .....
Spatial Photonics
...
SPEC ..... Spectra254 .... Spectragenetics .... Spectral Energies .....
Spectral
Systems .....
Spectranetics ...
SpectraWatt ... Spectro Coating ... SpectrumS4 ....
Speech
Tails ... Speer Medical .... Spero Therapeutics ..... Spinal
Modulation ..... Spinal
Restoration
... Spinal Simplicity ..... Spinal
Stabilization Technologies ..... SpineEX .... SpineGuard ...
Spineology
... Spine Wave .. Spintech .... Spin
Transfer
Technologies ....
SpiralGenetics .... Spiral Therapeutics .... Spiration
... Spire
... Spirox (formerly Nasoform) ..... Spoonflower .... Spotfire ... Spot
On Sciences ...
Spredfast
... Spring Bank Pharmaceuticals ... SpringLeaf Therapeutics
... SpringWorks .... SpringWorks Therapeutics ....
SPR Therapeutics
.... Spyrix ....SQZ
Biotech ..... SRL ... Staktek Holdings ... Standard
Bariatrics .... STAR Cryoelectronics
... Starfire ... Startech Environmental
... Startup Circle Pharma .... StarVision
Technologies .... Stasys Medical ..... SteadyMed Therapeutics
..... Stealth BioTherapeutics ..... Stealth
Therapeutics ... Steel City Optronics ....
Stellaray
.... Stellar Biotech .... Stellar Science ....
Stellent .... Stemagen ... StemBioSys .... Stem Cell Assurance (Now
BioRestorative Therapies) .... StemCells
... Stemcentrx ..... StemCo
Biomedical ... Stemgent ...
StemImmune ....
Stemina Biomarker
Discovery ... Stemonix ..... Stem Pharm .... Stereotaxis ...
Sterilmed ...... Sterling
Semiconductor ..... StimMed ..... Stirling Energy .... Stoke
Therapeutics ..... Stottler
Henke ... Straight Flight .... Stratagene ... Strata Oncology
..... Stratasys
... Stratatech
... Strategic Response Initiatives .... Stratos
Genomics
... Strella Biotechnology ..... Stromedix ....
Strongbridge
Biopharma .....
Sucampo Pharmaceuticals ..... Summit
Technology
.... Sun BioPharma ..... Sun Catalytix
.... Sunesis
Pharmaceuticals
.... SunHealth Solutions ... Suniva ....
Sunovion
Pharmaceuticals
... SunPower ... Sun Power Biodiesel ...
Sunrise
Ridge Algae ....Sunshine Heart .... Suntech ...
Suono ..... Superconductive
Components ... Superconductor Technologies ... SuperDimension ...
SuperFlex ..... Superior
Organoid Technologies ..... Supernus
Pharmaceuticals .... SuperPower ... Superprotonic
.... SupraSensor .....
Surefire
Medical
.... Surface
Logix
... Surface Oncology ..... Surgient ...
SurgiQuest
.... Surmet
... SurModics ... Suro Biopharma .....
Suros Surgical Systems
..... Surrozen .... SURVICE Engineering ..... Sustainable
Bioproducts .... Sustainable Oils ....
SustainX ... Sutro Biopharma ..... Sutron .....
SutroVax ..... SuturePro
Technologies (now Ceterix) .... SuviCA .... SuVolta ... Suzlon Rotor
... SVS
... SPEC ... Swallow Solutions .... SweetSpot Diabetes Care
... Swift Biosciences .... Syagen Technology
... Symbiomix Therapeutics ..... Symbiont Web
...
Symbotic ...
Symetrix .... Symic Biomedical ..... Symyx
Technologies
... Synack .... Synageva BioPharma ... SynAm Vaccine
....
SynapDx
....
Synaptics ... SynCardia Systems ..,.. Synchroneuron ....
SynchroPET .... Syndax
Pharmaceuticals
... Syndexa Pharmaceuticals .... Synedgen ....
Synergy
Biomedical
....
Synergy Pharma ..... SynGen .... Synlogic ..... Synopsys .... SynSonix
.... Synta
Pharmaceuticals ... Syntax-Brillian ... SyntheMed
... Synthetic Biologics ..... Synthetic Genomics
.... SyntheZyme .....
Synthorx ....
Syntimmune ..... Syntrix
Biosystems .... Syntronics .... Synvitrobio ..... Syros
Pharmaceuticals .... Sysgain .... Syslogic .... Systagenix Wound
Management .....
Systems and Processes Engineering
SPEC ... Systima Technologies ..... Sytera
T2
Biosystems ... T3D Therapeutics ..... Tabula ... Taconic
BioSciences ..... Tactical Engineering and Analysis ..... Tactile
Systems
Technology .... Tactiva Therapeutics ..... TAI Diagnostics .....
Talaris Therapeutics .... Talecris Biotherapeutics
... Talee Bio ..... Taligen Therapeutics
...
Talima Therapeutics ... Tal Medical ... Talon Therapeutics
... Tandem Diabetes Care ...
Tangen Biosciences
..... Tango
Therapeutics ..... Tanox ..Tantaline
.... TapImmune .... Tarari ...
.Targacept ...
TargeGen
... Targ-Anox ... Targanta
... Targazyme (formerly)America Stem Cell....
Targeson
... Targeted Genetics ... Targeted Growth
... Taris Biomedical .... Tarveda Therapeutics
..... Tascent .... Tauriga
Sciences
.... Taxa Biotechnologies ..... Taxon
Biosciences .... Taxus
Cardium (formerly Cardium Therapeutics) ... Taylor
Devices ..... TCR² Therapeutics ..... TDA
Research .... Tealium ..... TearScience
... TearSolutions .... Tech-X ....
Techniscan Medical Systems
... Technology
and Devices Int'l ... TechTol Imaging ... TELA Bio .....
Telecardia ...
TeleContinuity ... Telefactor ..... Telemedicine
Up Close operates as DxUpClose ...... Telik ... Tempest
Therapeutics ..... Templex
Technology... Tempus ..... Tenax Therapeutics .... Tenaya
Therapeutics ..... Tendril
...
Tendyne
Holdings ..... Tensha Therapeutics ...
Tepha
... TeraDiode .... TeraDiscoveries (now Cloud
Pharma) ....
Terapio ... TeraStor ...
Terrabon ...
Terrajoule ... TerraMetrics ... Terumo BCT .... Terus
Technologies .... TESARO ....
TeselaGen
Biotechnology .... Tessera
Technologies ... Tethys BioScience .... Tetra
Discovery
Partners .... Tetragenetics
... TetraLogic Pharmaceuticals ...
Tetraphase
Pharmaceuticals ... TetraVue ... Tezzaron
Semiconductor .... TFF Pharmaceuticals .... TGS Knee Innovations
... TG Therapeutics .... Thar Pharma .... Thalchemy ..... The
ExOne .... The Medicines ..... Therabron Therapeutics ..... Theraclone
Sciences
...
Theragenics
.... Therametric Technologies ... Theranos
....
Therion
Biologics ... Thermacore ... Thermage
...
Thermal Gradiant .... Thermal Spray Technologies
....
ThermalTherapeutic Systems
... Thermedical ...
ThermoAura ....
ThermoCeramiX .... ThermoGenesis .... Thermon ... TherOx ....
Thesan
Pharmaceuticals .... Theseus...
Thetis Pharmaceuticals ...
ThingMagic... Third Wave Technologies .. Thoratech
Tech
... Thorley Industries .... ThreeRivers 3D ..... Threshold
Pharmaceuticals .... Thrive Earlier Detection .....
ThromboVision .... Thyritope Biosciences
.... Tiax ... Tibbetts Industries
... Tibion ..... Tiburio
Therapeutics ..... Tilera ... Tillges
Technologies ... Tilos Therapeutics .... Tioma Therapeutics .....
TissueGene ..... TissueLink
... Tissue Regeneration Systems .... Titan
Pharmaceuticals .... Titan Spine ..... TJ Technologies .... TLC
Precision Wafer
... Tmunity Therapeutics .... Tobira Therapeutics ....
Tocagen
...
Tokai Pharmaceuticals .... Tolerx .... TomoTherapy
... Tone Tree ..... Topia Technology .... TopicalRemedy ....
Topokine Therapeutics
.... Torax
Medical ... Torque Therapeutics ..... Total Immersion
...
TotipotentRx .... Totus Solutions .... Toyon Research ..... TP
Therapeutics ..... Trace
Genomics ..... Tracon
Pharmaceuticals
... TranS1
.... TransAstra .... Transatomic Power .... Transcend Medical
...Transcept
Pharmaceuticals
.... TransCorp
..... Transcriptic ..... TransEnterix ... Transgenomic
...
Translattice
.....
TransMedics
... Transmeta ... TransMolecular
... Transphorm .....
TransTech
.... TransTech Pharma (now vTv Therapeutics) ... Transzyme
Transzyme Pharma ... Traverse
Biosciences ... Traycer
Diagnostic Systems ..... Trefoil Thera .... Trellis
Bioscience
... Trellis Earth Products ... Trethera
.... Trevena
... Trevi Therapeutics ..... Trex Enterprises ... Triad
Semiconductor .... Tri Alpha
Energy ..... Triangle
BioSystems .... Tribogenics
....
Tribologix
.... Trice Medical .... Trice
Orthopedics .... Tricida ..... Trident Systems ... Trilumina ....
Trimble Navigation
.... Trimeris
... Triquint
Semiconductor ...
Triton Systems ... Trius Therapeutics ...
TriVascular
Technologies .... Trovagene ..... Trubion
Pharmaceuticals ... Tru-D SmartUVC ..... True Diagnostics
....
True Health Diagnostics
.... True North Therapeutics .... Truestone ..... TruTouch Technologies
..... Try Eco ..... Tryton
Medical
... TScan Therapeutics ..... Tularik .... Turtle Mountain
Communications .... TVA Medical
... Tvardi Therapeutics .... Twelve .... Twentyeight-Seven
Therapeutics ...... Twin Star Medical ... Twist
Bioscience
..... TwoXAR ..... Tyme Technologies .... TypeZero Technologies ....
Tyrosine
Pharmaceuticals
....
Tyrx
uBiome .... UCAN ... UES
... Ulthera .... UltraCell ... Ultragenyx
....
Ultralife Batteries
...
Ultramet... Ultradian
Diagnostics ..... Ultraviolet Sciences ... Unbounded Robotics
.... Unchained Labs .... UNIAX
... Unica
... Unidym ... UniEnergy Technologies ..... Unified
Nexsys
.... Unilife ..... Uni-Pixel .... Uniqure
.... United
Devices ... United
Therapeutics
... United Therapies ..... Unity Biotechnology .... Universal
Cells ...... Universal
Display ... Universal
Robots ..... Universal
Technical Resources .... Universal
Technology .... Unleash Immuno
Oncolytics ..... Unum Therapeutics .... Unwired
Nation ... Uptake Medical
... UQM Technologies ... Urbix Resources ....
Urigen
Pharmaceuticals
.... UroGene Pharma ..... US
Nanocorp ... Uroplasty ..... US Bioscience ..... US
Silicones ... UTC Power .... Utilidata ... Utron
.....
UVision360
Vaccinex ..... Vaccinogen .... Vader Systems ..... VakSea ....
Vala Sciences
....Valencell ... Valence Technology .... Validity
Sensors
... Valmont Industries .... Vanda Pharmaceuticals
... Vanguard Space Technologies ..... Vapogenix ..... Variant
Pharmaceuticals ..... Vascudyne ..... Vascular
Biogenics (also VBL Therapeutics) .....
Vascular
Designs ... Vascular Genesis ..... Vascular Pathways
...
Vascular Pharmaceuticals ....
Vascular Solutions .....
Vasculox .... VasoGenix
Pharmaceuticals ... Vasoptic Medical ..... Vast Therapeutics
.... Vativ
Technologies ... Vaxart ... Vaxess
Technologies ....
VaxGen
...
VaxInnate ... vCalc .... Vecna Tech ...
Vectorlogics
....
Vedanta
Biosciences
.... Veeva Systems .... Veezyon
... VeinAid ... Velano Vascular .... Velicept
Therapeutic
..... Velocimed ...
Velomedix
... VelosBio ..... VenatoRx Pharmaceuticals ..... Venaxis
..... Vendormate
....
Veniti ... Vensun
Pharmaceuticals ....
VentiRx
...
Ventria Bioscience
... Ventrix ..... Ventrus
Biosciences ... Veracode
... Veracyte
... Veran Medical Technologies ..... Verastem
... VeraSun Energy
... VerAvanti .... Verax
Biomedical ... Verdezyne ... Vergent Bioscience .....
VerinataHealth ...
Verenium ... Vericel (formerly Aastrom Bio) .... Verifica-BG
... Veritas Genetics .....
Vermillion .... Vermont
Composites ...Veros Systems ... Verrica Pharmaceuticals .... Versar
.... Versartis ...
Vestagen
Technical
Textiles .... Vestaron .... VerteCore ..... VerteraSpine ..... Vertex
Pharmaceuticals ... VeruTEK Technologies ... Verve
Therapeutic .... Vesper
Medical
..... Vextec
... VGBioCogCubed .... V-Glass .... VGo
Communications ... VGX Pharmaceuticals ..... ViaCell
... ViaCyte
.... Viacor
.... Viamet Pharmaceuticals
... ViaSat
... Via Separations .... Vical . .. Vicarious .... Vicus Technologies
.... Vidacare VIDA Diagnostics ..... ... View .....
Vigene Biosciences .... Viking
Therapeutics .... Vion
Pharmaceuticals
... ViraCor Laboratories ... Viracta Therapeutics ..... Viral
Genetics ....
Virdante Pharmaceuticals ...
Virdia
.... Virent Energy Systems ... Viresco Energy
... Virobay .... ViroPharma . .. ViroXis ...
Virtify .
VirtualScopics
.... Virtusa
... Viscardia ..... VisEn Medical ... VisiGen
Biotechnologies
... VisionGate ..... VisionQuest ..... Vision-Sciences
... Vistagen
Therapeutics ... Vistec
Lithography ... Visterra ...
Visualase .... Vitae Pharmaceuticals ..... VitalMedix
... Vital Therapies ...... Vital Vio .... VitaPath Genetics
... Vitriflex .... Vium ..... Vivex Biomedical
.... Vividion Therapeutics ..... Vivisimo .... Vixar
... Vixel ... Vixiar Medical ..... Vizzario .... Vlingo
... VLST ..... VMware ... Voci Technologies .... Volcano ....
VoltServer ... VORAGO Technologies (previously Silicon
Space Technology) ..... Vorbeck Materials
... Vor BioPharma ..... Vortex Biosciences ..... Vortex
Medical
... Voxel
.. voxeljet ..... Voyager Therapeutics
.... Vtesse ....
VT
Silicon
.... vTv Therapeutics (formerly TransTech Pharma) ..... VUV Analytics
.... Vuzix .... Vyriad .... Vyrx
Pharmaceuticals ..... VytronUS
WaferGen
Biosystems ...
Wakonda Technologies ... Walker Magnetics Group ...
Waste2Watergy
.... Waveband
..... Wave Computing ..... Waveguide ..... WaveRx ... Weinberg Medical
Physics .... WellStat
Therapeutics .... Whole Biome ..... Whole
Trees
.....
WiBotic .... Wicab ..... WildcatDiscovery .... Wiliot .....
Willow Garage
...
Wilocity
.... Wilson
Greatbatch
.. Wilson Tool International .... Wilson Wolf Manufacturing
...
WiMax.com ...
Windlift ... Windtree
Therapeutics ..... WinSanTor .... Wintegra ... WISErg .... Wizbe
Innovations ...
WMR
Biomedical (now Arsenal Medical) ... Wolf Technical
Services ... WoundZoom .... Woven Orthopedic Technologies
....
Wright Materials Research
... Wright Therapy Products ..... W Solar
Group
X4 Pharmaceuticals ..... Xanofi ... Xanthus
Pharmaceuticals
... XBiotech USA ..... X-Body Biosciences
... Xcede Technologies ..... XCELL BIOLOGIX .....
Xcell Biosciences
....
Xcellerex ... XChanger
Companies .... Xencor .... X-energy ..... Xenetic Biosciences ....
Xenex
Disinfection Services .... Xenex
Healthcare Services ... XenoGen Biosystems .... Xenomics
... Xenoport ... Xeris
Pharmaceuticals ... Xetrios Therapeutics .... XF
Technologies .... xG Technology .... Xidex ... Xitronix
... XL
Hybrids ... Xlumena .... Xoc Pharmaceuticals ..... Xollai ...
Xolve
(formerly
Graphene Solutions)
... Xoma
... XProSciences (now Icagen) ..... X-Ray Optical .... X-Spine
.... XSunX
...
Xtalic .. Xtant Medical
Holdings ..... Xtent ...Xtreme Power
... XTuit Pharmaceuticals ....
Xunlight .... XyloCor Therapeutics .... Xynomic
Pharma
Yan Engines ... Yardney Technical Products .... Y-Carbon ... Yulex .... Yumanity Therapeutics .... Yurie
Z ... Zacharon Pharmaceuticals .... ZafGen .... Zavante Therapeutics ..... ZBB Energy ... ZeaChem ... ZeaKal .... Zebra Imaging .... Zebra Medical Vision (Israel) ..... Ze-gen ... ZenBio ... Zenomics .... Zenverge ..... Zeo .... Zephyr Technology ... ZeptoMetrix .... ZeroFOX .... Zero Locus .... Zero Mass Water .... ZetaRx Biosciences .... Zeteo Tech .... Zilker Labs ... Zinc Matrix Power ... Zintera ..... Ziopharm Oncology ... Ziptronix .... Zogenix ... Zosano Pharma ... ZPower ... ZS Genetics ..... zSpace ..... ZS Pharma ... ZSX Medical .... Zumobi ... Zunum Aero ..... Zurex Pharma ... Zwitter Technology .... Zyga Technology .... Zygo ... Zymergen ..... ZymoGenetics ... Zynerba Pharmaceuticals .....Zymeworks ..... Zyomyx ... Zystor Therapeutics ... Zyvex Technologies